PPAR

In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms.

Cat. No.	Product Name	CAS No.	Purity
T69146	Suksdorfin 化合物 Suksdorfin	53023-17-9	98%
T69146	Suksdorfin 具有降血糖作用，可促进脂肪细胞分化并增强脂联素的产生，可激活过氧化物酶体增殖物激活受体 γ （PPARγ），可促进脂肪细胞对胰岛素依赖性葡萄糖的摄取，可用于肥胖相关研究。
T15243	Ertiprotafib 化合物 T15243	251303-04-5	98%
T15243	Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPA...
TN5091	Tagitinin A 化合物 TN5091	59979-61-2	98%
TN5091	Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the g...
T27519	GW 9578 化合物 GW 9578	247923-29-1	98%
T27519	GW 9578 是一种具有选择性和有效性的 PPARα 激动剂，具有有效的降脂活性，可用于研究牛皮癣，关节炎，脱发，哮喘和I型糖尿病。
TN2228	Soyasaponin Aa 大豆皂苷Aa	117230-33-8	98%
TN2228	Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the down...
TN4094	Gallocatechin gallate 化合物 TN4094	5127-64-0	98%
TN4094	Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation throu...
TN5149	Tirotundin 化合物 TN5149	56377-67-4	98%
TN5149	Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
TN4860	Pueroside B 化合物 TN4860	100692-54-4	98%
TN4860	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
TN3152	6-Acetonyldihydrochelerythrine 化合物 TN3152	22864-92-2	98%
TN3152	6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
T14356	AVE-8134 化合物 T14356	304025-09-0	98%
T14356	AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.
TN2535	1-Hydroxy-2-oxopomolic acid 化合物 TN2535	217466-37-0	98%
TN2535	1β-Hydroxy-2-oxopomolic acid inhibits adipocyte differentiation through downregulation of various adipocytokines by blocking PPARγ and C/EBPα expression.
T10327	Ankaflavin 红曲黄素	50980-32-0	98%
T10327	Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induc...
T12529	Pparδ agonist 2 化合物 T12529	870884-12-1	98%
T12529	Pparδ agonist 2 is an agonist of PPARδ.
TN1703	Glycyrin 格里西轮	66056-18-6	98%
TN1703	Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
T11754	Ketorolac-d5 化合物 T11754	1215767-66-0	98%
T11754	Ketorolac D5, a deuterium-labeled version of Ketorolac, is a non-steroidal anti-inflammatory agent that functions as a nonselective COX inhibitor. It exhibits IC...
T15748	LG100754 化合物LG100754	180713-37-5	98%
T15748	LG100754 (UVI 2112)是一种通过RXR 发挥作用的胰岛素增敏剂。LG100754是RXR 二聚体调节剂。LG100754是RXR:RXR 同二聚体拮抗剂，以及RXR:PPARα和RXR:PPPARγ异二聚体的激动剂。
TQ0272	Balaglitazone 巴格列酮	199113-98-9	98%
TQ0272	Balaglitazone is a selective partial agonist for PPARγ (EC50: 1.351 μM for human PPARγ).
T17189	U-46619 化合物U-46619	56985-40-1	98%
T17189	U-46619是一种有效的TXA2激动剂，是一种血栓素A2类似物（内过氧化物），有诱导肌球蛋白轻链9 (Myl9)基因缺失小鼠主动脉平滑肌(SM)收缩的功能。
TN2641	15-Methoxypinusolidic acid 化合物 TN2641	769928-72-5	98%
TN2641	15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methox...
T10506	PPAR agonist 1 化合物 T10506	539813-69-9	98%
T10506	PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.