PDK

In the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in humans. It is implicated in the development and progression of melanomas.PDPK1 is a master kinase, which is crucial for the activation of AKT/PKB and many other AGC kinases including PKC, S6K, SGK. An important role for PDPK1 is in the signalling pathways activated by several growth factors and hormones including insulin signaling.

Cat. No.	Product Name	CAS No.	Purity
TMA2474	δ-Tocotrienol δ-生育三烯酚	25612-59-3	97.38%
δ-Tocotrienol (Delta-Tocotrienol) 是一种维生素 E，存在于蔬菜，水果，种子，坚果，谷物和油等。维生素 E 是抗氧化剂、神经保护剂和抗癌剂，可以降低胆固醇和其他脂质，保护心血管疾病。
T12412L	PDK4-IN-1 hydrochloride 化合物PDK4-IN-1 hydrochloride	2310262-11-2	98%
PDK4-IN-1 hydrochloride 是一种蒽醌衍生物，对丙酮酸脱氢酶激酶 4有抑制作用，IC50为 84 nM，具有口服活性。它抑制细胞转化和细胞增殖并诱导细胞凋亡。它具有抗过敏，抗糖尿病和抗癌作用。
T19783	Dehydroabiethylamine 脱氢松香胺	1446-61-3	98%
Dehydroabiethylamine (NSC-2955) 是肝脏 CYP2B 活性的诱导剂。 Dehydroabiethylamine 抑制丙酮酸脱氢酶激酶 (PDK) 和细胞内胆固醇转运，具有抗肿瘤活性。
T4046	BX517 化合物BX517	850717-64-5	98%
BX517 (PDK1 inhibitor 2) 是一种选择性 PDK1抑制剂，其 IC50=6 nM。
T0809	Dicoumarol 双香豆素	66-76-2	98%
Dicoumarol (Dicumarol) 是一种 NAD(P)H: 醌氧化还原酶 1 和PDK1的抑制剂，它们的IC50值分别为 0.37 和 19.42 μM。

Cat. No.

Product Name

CAS No.

Purity

Chemical Structure

TMA2474

δ-Tocotrienol

δ-生育三烯酚

25612-59-3

97.38%