Hydroxylase

Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound. In biochemistry, hydroxylation reactions are often facilitated by enzymes called hydroxylases. Hydroxylation is the first step in the oxidative degradation of organic compounds in air. It is extremely important in detoxification since hydroxylation converts lipophilic compounds into water-soluble (hydrophilic) products that are more readily removed by the kidneys or liver and excreted. Some drugs (for example, steroids) are activated or deactivated by hydroxylation.

Cat. No.	Product Name	CAS No.	Purity
T10142	P-Ethynylphenylalanine 4-乙炔基苯丙氨酸	278605-15-5	98.04%
T10142	p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) 是一种色氨酸羟化酶(TPH)抑制剂，具有竞争性、有效性、选择性和可逆性，Ki 为32.6 μM。
T3268	Mildronate 米屈肼	76144-81-5	98%
T3268	Mildronate (Meldonium) 是心血管保护药，能够竞争性的抑制 BBOX1和 OCTN2。作用于人重组 BBOX 的(IC50:34-62 μM)、人 OCTN2 (EC50:21 μM)。它 n 能够诱导长链脂肪酸代谢从线粒体向过氧化物酶体的重定向。
T15796	LX-1031 化合物LX-1031	945976-76-1	97.97%
T15796	LX-1031 是一种有效的色氨酸 5-羟化酶抑制剂。 LX-1031 减少外周5-羟色胺的合成。
T13383	Zamicastat 化合物Zamicastat	1080028-80-3	97.43%
T13383	Zamicastat (BIA 5-1058) 是多巴胺 β-羟化酶 (DBH) 抑制剂，可透过血脑屏障引起中枢和周边效应，具有降血压作用。它也是一种浓度依赖性的双重 P-gp 和 BCRP 抑制剂，IC50值分别为 73.8 和 17.0 μM。
T10142L	P-Ethynylphenylalanine hydrochloride 化合物p-Ethynylphenylalanine hydrochloride	188640-63-3
T10142L	p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) 是一种高效的、可逆的、选择性的、竞争性的色氨酸羟化酶 (TPH) 抑制剂，其Ki=32.6 μM。
T83969	Casein 酪蛋白	9000-71-9	98%
T83969	Casein 是一种具有多种作用的牛奶蛋白，参与新型药物递送系统，通过其胃内凝血特性以不同的方式影响餐后氨基酸递送。
T15779	LP-533401 hydrochloride 化合物 T15779	1040526-12-2	98%
T15779	LP-533401 hydrochloride is an inhibitor of tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.
T61214	EWP 815 化合物EWP 815	20231-01-0	98%
T61214	EWP 815 is a disulfiram analogue that functions as a powerful inhibitor of Ins(1,4) P 2 phosphatase, Ins(1,4,5) P 3 5-phosphatase, and dopamine β-hydroxylase act...