GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product Name	CAS No.	Purity
TN1717	Guvacine 去甲槟榔次碱	498-96-4	98%
TN1717	Guvacine can enhance the inhibition of spinal neurones by GABA.
T12867L	SCH 50911 化合物 T12867L	733717-87-8	98%
T12867L	SCH 50911 is (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid and is a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, b...
T17215	Valnoctamide 化合物 T17215	4171-13-5	98%
T17215	Valnoctamide inhibits benzodiazepine-refractory status epilepticus. Valnoctamide acts directly on GABAA receptors.
TN4440	Limonexic acid 化合物 TN4440	99026-99-0	98%
TN4440	Limonexic acid shows antinociceptive actions , it produces dose-related inhibition of glutamate- and capsaicin-induced pain. Limonexic acid can effectively prote...
T15737	Lesogaberan 化合物 T15737	344413-67-8	98%
T15737	Lesogaberan is an effective and selective GABAB receptor agonist (EC50: 8.6 nM for human recombinant GABAB receptors). For rat brain GABAB and GABAA receptors, t...
T10456	Bamaluzole 巴马鲁唑	87034-87-5	98%
T10456	Bamaluzole is an agonist of GABA receptor.
TN4322	Isopulegol 化合物 TN4322	7786-67-6	98%
TN4322	Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
T10869L	CP-409092 化合物 T10869L	194098-25-4	98%
T10869L	CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.
T9946	MIDD0301 化合物MIDD0301	2187489-08-1	98%
T9946	MIDD0301是一种有效的正变构α5β3γ选择性GABAA 受体（GABAAR）配体，EC50为17 nM。
TN1842	Kushenol I 苦参醇	99119-69-4	98%
TN1842	Kushenol I is a GABAA receptor modulator, it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).Kushenol I is shown to be activ...
T12867	SCH 50911 hydrochloride 化合物 T12867	160415-07-6	98%
T12867	SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).
T11350	GABAB receptor antagonist 1 化合物 T11350	797-17-1	98%
T11350	(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective an...
T17306	(R)-Baclofen hydrochloride (R)-巴氯芬盐酸盐	63701-55-3	98%
T17306	Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to...
T4S1616	Sanggenon D 桑根酮D	81422-93-7	98%
T4S1616	Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamma...
TN3702	(-)-Corlumine 化合物 TN3702	79082-64-7	98%
TN3702	Corlumine exhibits spasmolytic and GABA antagonist activity.
T4655	Pipequaline 哌夸林	77472-98-1	98%
T4655	Pipequaline (PK-8165) 是一种苯二氮卓受体部分激动剂，有抗焦虑作用。
TN3868	Dihydroxyaflavinine 化合物 TN3868	76410-56-5	98%
TN3868	Dihydroxyaflavinine is a fungal toxin, it inhibits non-competitively GABAA receptor channel expressed in Xenopus oocytes.Dihydroxyaflavinine shows oral toxicity ...
TN4298	Isohyenanchin 化合物 TN4298	19417-00-6	98%
TN4298	Isohyenanchin is the potent antagonist of RDLac homo-oligomers, it is also a weak antagonist of ionotropic GABA receptors.
T12044	(-)-Bicuculline methochloride 化合物 T12044	53552-05-9	98%
T12044	(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
T3927	Phellopterin 珊瑚菜素	2543-94-4	99.99%
T3927	Phellopterin 是一种分离自P. trifoliata 中的天然产物。它能够调节 Akt 和 PKC 通路，抑制 TNF-alpha 诱导的 VCAM-1 表达，进而减少单核细胞与内皮细胞的粘附。