Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
TN4913 | Riddelline
化合物 TN4913
|
23246-96-0 | 98% |
|
Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver. | ||||
TN3691 | Communic acid
化合物 TN3691
|
2761-77-5 | 98% |
|
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic... | ||||
TN4227 | Horminone
化合物 TN4227
|
21887-01-4 | 98% |
|
Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi,... | ||||
T17071 | Thiarabine
化合物 T17071
|
26599-17-7 | 98% |
|
Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis. | ||||
TN1374 | α-Chaconine
阿尔法卡茄碱
|
20562-03-2 | 98% |
|
Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Al... | ||||
TN5011 | Shizukaol B
化合物 TN5011
|
142279-40-1 | 98% |
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl... | ||||
TN2529 | 1-Decarboxy-3-oxo-ceanothic acid
化合物 TN2529
|
214150-74-0 | 98% |
|
1-Decarboxy-3-oxo-ceanothic acid shows in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, the cytotoxic effect is mediated, at least in par... | ||||
T13479 | 2-Keto-D-galactose
D-半乳糖酮
|
54142-77-7 | 98% |
|
2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells. | ||||
TN4437 | Licorisoflavan A
化合物 TN4437
|
129314-37-0 | 98% |
|
Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential for the development of novel host-modulating ... | ||||
T15094 | Dehydroaltenusin
脱氢阿霉素
|
31186-13-7 | 98% |
|
Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM). Dehydroaltenusin inhibits ma... | ||||
T73367 | Zn(BQTC)
化合物 Zn(BQTC)
|
2785342-54-1 | 98% |
|
Zn(BQTC)为高效线粒体DNA(mtDNA)及核DNA(nDNA)抑制剂,能对二者造成严重损伤,进而影响线粒体与核功能。该化合物激活DNA损伤诱导的细胞凋亡信号通路并对A549R细胞显示出选择性抗增殖效果,适用于抗癌研究领域。 | ||||
T74630 | RNA polymerase II-IN-1
化合物 RNA polymerase II-IN-1
|
2891451-07-1 | 98% |
|
RNA polymerase II-IN-1(compound 19iv)是一款鹅膏毒素类化合物,能够抑制RNA聚合酶II(Pol II),其半抑制浓度IC50为36.66 nM。该化合物相较于α-Amanitin,对癌细胞展现出更高的细胞毒性,而对正常细胞的毒性较低。 | ||||
T36667 | 2'-Deoxyadenosine-5'-triphosphate
2'-脱氧腺苷 5'-三磷酸酯
|
1927-31-7 | 98% |
|
2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) 是一种天然存在的小分子核苷酸,在细胞中用于DNA合成或复制。2'-Deoxyadenosine-5'-triphosphate (dATP) 是 DNA 聚合酶的底物。2'-D... | ||||
TQ0016 | NKP-1339
化合物NKP-1339
|
197723-00-5 | 98% |
|
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. | ||||
T16749 | Rifalazil
利福拉齐
|
129791-92-0 | 98% |
|
Rifalazil is a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymeras... | ||||
TMA0291 | Dehydroglyasperin D
化合物 TMA0291
|
517885-72-2 | 98% |
|
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h... | ||||
TN2507 | 1,6,7-Trihydroxyxanthone
化合物 TN2507
|
25577-04-2 | 98% |
|
1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell gro... | ||||
T23384 | SR 11302
化合物SR 11302
|
160162-42-5 | 98% |
|
SR 11302 是一种类视黄醇,是一种激活蛋白-1 转录因子抑制剂,能够特异性抑制 AP-1 活性,而不会激活视黄酸反应元件 (RARE) 的转录。 | ||||
TN1660 | Ganoderic acid C1
灵芝酸C1
|
95311-97-0 | 98% |
|
Ganoderic acid C1 是分离自 G. lucidum 中的天然产物,能够抑制小鼠巨噬细胞TNF-α 的生成。 | ||||
TN5153 | Torilin
窃衣素
|
13018-10-5 | 98% |
|
Torilin 是一种睾酮5α还原酶抑制剂,它(IC50=31.7+/-4.23μM)对5α还原酶的抑制作用强于α-亚麻酸(IC50=160.3+/-24.62μM),但弱于非那雄胺(IC50=0.38+/-0.06μM)。Torilin 具有免疫调节、肝脏保护和抗炎特性,它通过限制 TAK1介导的 MAP 激酶和 NF... |