首页 工具
登录
购物车
COX

COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.
1 2 3 4 5 ... 20
Cat. No. Product Name CAS No. Purity Chemical Structure
TN2775 2-Methoxystypandrone
化合物 TN2775
85122-21-0 98%
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
TN4446 Longiferone B
化合物 TN4446
1639810-67-5 98%
Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression.
T10152L 4-Methylamino antipyrine hydrochloride
化合物 T10152L
856307-27-2 98%
4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibit...
TN4420 Latifolin
化合物 TN4420
10154-42-4 98%
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
TN3922 Effusanin E
化合物 TN3922
76470-15-0 98%
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
TN4586 Mulberrofuran A
化合物 TN4586
68978-04-1 98%
Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy...
TN4584 Morolic acid
化合物 TN4584
559-68-2 98%
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent change...
T17036 Tenidap
化合物 T17036
120210-48-2 98%
Tenidap is a non-steroidal anti-inflammatory drug and is a selective COX-1 inhibitor (IC50: 0.03 µM and 1.2 µM for COX-1 and COX-2, respectively). Tenidap is als...
TN5019 Siegeskaurolic acid
化合物Siegeskaurolic acid
52645-97-3 98%
Siegeskaurolic acid 是一种具有抗炎活性的天然产物。
T13263 COX/5-LO-IN-1
化合物 T13263
154355-75-6 98%
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.
TN4879 Questinol
化合物 TN4879
35688-09-6 98%
Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit th...
TN3070 4beta-Hydroxywithanolide E
化合物 TN3070
54334-04-2 98%
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progr...
T4S1616 Sanggenon D
桑根酮D
81422-93-7 98%
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamma...
T15630 Tilmacoxib
替马考昔
180200-68-4 98%
Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).
T15449 GW-406381
化合物 T15449
221148-46-5 98%
GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats followin...
TN4162 Goshonoside F5
化合物 TN4162
90851-28-8 98%
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
TN3810 Dehydroperilloxin
化合物 TN3810
263241-09-4 98%
Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC(50) value of 30.4 microM.
T12419 PF-04634817 succinate
化合物 T12419
2140301-98-8 98%
PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.
TN4581 Moracin D
化合物 TN4581
69120-07-6 98%
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
TN1562 Dehydromiltirone
去氢丹参新酮
116064-77-8 98%
Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF...
2-Methoxystypandrone
TN2775
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
Longiferone B
TN4446
Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression.
4-Methylamino antipyrine hydrochloride
T10152L
4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibit...
Latifolin
TN4420
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
Effusanin E
TN3922
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
Mulberrofuran A
TN4586
Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy...
Morolic acid
TN4584
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent change...
Tenidap
T17036
Tenidap is a non-steroidal anti-inflammatory drug and is a selective COX-1 inhibitor (IC50: 0.03 µM and 1.2 µM for COX-1 and COX-2, respectively). Tenidap is als...
Siegeskaurolic acid
TN5019
Siegeskaurolic acid 是一种具有抗炎活性的天然产物。
COX/5-LO-IN-1
T13263
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.
Questinol
TN4879
Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit th...
4beta-Hydroxywithanolide E
TN3070
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progr...
Sanggenon D
T4S1616
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamma...
Tilmacoxib
T15630
Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).
GW-406381
T15449
GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats followin...
Goshonoside F5
TN4162
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
Dehydroperilloxin
TN3810
Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC(50) value of 30.4 microM.
PF-04634817 succinate
T12419
PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.
Moracin D
TN4581
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
Dehydromiltirone
TN1562
Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF...
1 2 3 4 5 ... 20
联系我们
400-820-0310

上海市静安区江场三路238号8楼