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COX

COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.
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Cat. No. Product Name CAS No. Purity Chemical Structure
TN3482 Bakkenolide B
化合物 TN3482
18455-98-6 98%
Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.
TN4062 Flavidin
化合物 TN4062
83924-98-5 98%
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should...
T19886 Cirsilineol
甲基条叶蓟素
41365-32-6 98%
Cirsilineol (Eupatrin) 是从 Artemisia vestita Wall 的草本植物中分离出来的,具有免疫抑制、抗增殖和抗肿瘤特性。 Cirsilineol 通过线粒体途径选择性诱导细胞凋亡。
T16419 Oxyphenbutazone
羟布宗
129-20-4 98%
Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively...
TN2327 Zedoarondiol
化合物Zedoarondiol
98644-24-7 98%
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs...
TN4582 Moracin T
化合物 TN4582
1146113-27-0 98%
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
TN4748 Penduletin
化合物 TN4748
569-80-2 98%
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
TN2534 1-Hydroxy-2,3,5-trimethoxyxanthone
化合物 TN2534
22804-49-5 98%
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
TN4212 Hirsutanonol
(S)-1,7-双(3,4-二羟基苯基)-5-羟基-3-庚酮
41137-86-4 98%
Hirsutanonol 是来自桤木树皮的次生代谢物。 Hirsutanonol 具有有效的抗氧化和自由基清除活性,并对线粒体脂质过氧化具有抑制作用。 Hirsutanonol 可用于治疗特应性皮炎的研究。
T11169 Eicosatetraynoic acid
化合物 T11169
1191-85-1 98%
Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygen...
TN4463 Lupeolic acid
化合物 TN4463
87355-32-6 98%
Lupeolic acid has anti-inflammatory activity.
TN4064 Flavoglaucin
化合物 TN4064
523-73-9 98%
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
TN1755 Hyperforin
贯叶金丝桃素
11079-53-1 98%
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
T11660 Insulin levels modulator
化合物 T11660
1019254-94-4 98%
Insulin level regulators can be used to treat diabetes.
TN4783 Picralinal
化合物 TN4783
20045-06-1 98%
Picralinal has anti-inflammatory and analgesic effects.
TN4489 Manassantin A
化合物 TN4489
88497-87-4 98%
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
TN5149 Tirotundin
化合物 TN5149
56377-67-4 98%
Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
TN4860 Pueroside B
化合物 TN4860
100692-54-4 98%
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
TN3839 Desoxo-narchinol A
化合物 TN3839
53859-06-6 98%
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity agains...
TN2223 Soyacerebroside I
化合物Soyacerebroside I
114297-20-0 98%
Soyacerebroside I demonstrates a potent tyrosinase inhibitory activity.
Bakkenolide B
TN3482
Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.
Flavidin
TN4062
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should...
Cirsilineol
T19886
Cirsilineol (Eupatrin) 是从 Artemisia vestita Wall 的草本植物中分离出来的,具有免疫抑制、抗增殖和抗肿瘤特性。 Cirsilineol 通过线粒体途径选择性诱导细胞凋亡。
Oxyphenbutazone
T16419
Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively...
Zedoarondiol
TN2327
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs...
Moracin T
TN4582
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
Penduletin
TN4748
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
1-Hydroxy-2,3,5-trimethoxyxanthone
TN2534
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
Hirsutanonol
TN4212
Hirsutanonol 是来自桤木树皮的次生代谢物。 Hirsutanonol 具有有效的抗氧化和自由基清除活性,并对线粒体脂质过氧化具有抑制作用。 Hirsutanonol 可用于治疗特应性皮炎的研究。
Eicosatetraynoic acid
T11169
Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygen...
Lupeolic acid
TN4463
Lupeolic acid has anti-inflammatory activity.
Flavoglaucin
TN4064
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
Hyperforin
TN1755
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
Insulin levels modulator
T11660
Insulin level regulators can be used to treat diabetes.
Picralinal
TN4783
Picralinal has anti-inflammatory and analgesic effects.
Manassantin A
TN4489
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
Tirotundin
TN5149
Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
Pueroside B
TN4860
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
Desoxo-narchinol A
TN3839
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity agains...
Soyacerebroside I
TN2223
Soyacerebroside I demonstrates a potent tyrosinase inhibitory activity.
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