Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
TN3726 | Cudraflavone B
化合物 TN3726
|
19275-49-1 | 98% |
|
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo... | ||||
TN4046 | Excisanin A
化合物 TN4046
|
78536-37-5 | 98% |
|
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote... | ||||
TN1728 | Hellebrigenin
蟾蜍它里定
|
465-90-7 | 98% |
|
Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. H... | ||||
TN3517 | Bisacurone
化合物 TN3517
|
120681-81-4 | 98% |
|
Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressi... | ||||
T10275 | AKT-IN-3
化合物 T10275
|
2374740-21-1 | 98% |
|
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exh... | ||||
TN1379 | Alphitolic acid
化合物Alphitolic acid
|
19533-92-7 | 98% |
|
Alphitolic acid is a potent Hh/GLI signaling inhibitor, it shows an important relationship between Hh/GLI signaling inhibition, the decrease of BCL2, and cytotox... | ||||
TN3655 | Cimiside E
化合物 TN3655
|
154822-57-8 | 98% |
|
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,... | ||||
T16155 | MSN-125
化合物 T16155
|
1592908-16-1 | 98% |
|
MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxic... | ||||
TN3486 | Bakkenolide IIIa
化合物 TN3486
|
915289-60-0 | 98% |
|
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB... | ||||
TN3806 | Dehydroglyasperin C
化合物 TN3806
|
199331-35-6 | 98% |
|
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop... | ||||
TN1462 | Cajanin
2',4',5-三羟基-7-甲氧基异黄酮
|
32884-36-9 | 98% |
|
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol ef... | ||||
T11960 | MBM-55
化合物MBM-55
|
2083622-09-5 | 99.98% |
|
MBM-55 是一种有效的中心体相关激酶 2 (NEK2) 抑制剂,IC50 为 1 nM。 MBM-55 通过诱导细胞周期停滞和凋亡有效抑制癌细胞的增殖。 | ||||
T3881 | Vaccarin
王不留行黄酮苷
|
53452-16-7 | 99.97% |
|
Vaccarin 是从王不留行中提取的一种黄酮糖苷,可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。 | ||||
T6S0525 | Farrerol
杜鹃素
|
24211-30-1 | 99.96% |
|
Farrerol 是一种杜鹃花的生物活性成分,具有抗氧化、抗肿瘤、抗炎、神经保护和肝保护等多种功能。 | ||||
T2492 | Perifosine
哌立福新
|
157716-52-4 | 99.94% |
|
Perifosine (KRX-0401) 是一种具有口服活性的烷基磷酸胆碱 Akt 抑制剂,具有抗肿瘤活性。 | ||||
T6S0781 | Phellodendrine
黄柏碱
|
6873-13-8 | 99.94% |
|
Phellodendrine (Phallodendrin) 是异喹啉生物碱,是黄柏皮层中的重要特征成分之一。它具有良好的抗氧化,抗炎作用。它通过调节AKT/NF-κB 途径抵抗 AAPH 诱导的氧化应激。 | ||||
T2P2806 | Hederacolchiside A1
革叶常春藤皂苷 A1
|
106577-39-3 | 99.92% |
|
Hederacolchiside A1 (Raddeanoside R13) 是从白头翁中分离的一种有抗利什曼原虫和抗肿瘤增殖活性的天然产物。 | ||||
T13803 | N-Oleoyl glycine
化合物N-Oleoyl glycine
|
2601-90-3 | 99.92% |
|
N-Oleoyl glycine 是一种脂氨酸。在 3T3-L1 脂肪细胞中,N-Oleoyl glycine 通过激活CB1受体和Akt 信号通路来刺激脂肪形成。 | ||||
T6S0619 | Pachymic acid
茯苓酸
|
29070-92-6 | 99.91% |
|
Pachymic acid (3-O-Acetyltumulosic acid) 是来自茯苓的一种三萜,可抑制Akt 和ERK 信号传导途径。 | ||||
T3001 | Honokiol
和厚朴酚
|
35354-74-6 | 99.87% |
|
Honokiol (NSC-293100) 是厚朴提取物的活性成分,靶向多种信号分子,具有抗氧化,抗炎,抗血管生成和抗癌活性。它可抑制 Akt 的激活并增强 ERK1/ERK2 的磷酸化。 |