5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product Name	CAS No.	Purity
T16283	Neocarzinostatin 化合物 T16283	9014-02-2	98%
T16283	Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic. It recognizes double-stranded DNA bulge and induces DNA double strand breaks (DSBs). Neocar...
TN2116	Pteropodine 钩藤碱 C	5629-60-7	98%
TN2116	Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects,...
T10996	Deramciclane 化合物 T10996	120444-71-5	98%
T10996	Deramciclane has high affinity for 5-HT2A and 5-HT2C receptors. It acts as an antagonist in both receptor subtypes and has inverse agonist properties for 5-HT2C ...
T17253	WAY 163909 化合物 T17253	428868-32-0	98%
T17253	WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).
T15552	Iferanserin 化合物 T15552	58754-46-4	98%
T15552	Iferanserin (S-MPEC) is a selective antagonist of the 5-HT receptor (serotonin receptor) with an affinity for 5-HT2A receptors. Iferanserin has the potential fo...
TN1755	Hyperforin 贯叶金丝桃素	11079-53-1	98%
TN1755	Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
T22340	Granisetron 格拉司琼	109889-09-0	98%
T22340	Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
T10192	7-Desmethyl-3-hydroxyagomelatine 化合物 T10192	166527-00-0	98%
T10192	7-Desmethyl-3-hydroxyagomelatine is a metabolite of Agomelatine and has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and 5...
T26622	Ampreloxetine 阿普罗西汀	1227056-84-9	98%
T26622	Ampreloxetine (TD-9855) 是一种)去甲肾上腺素再摄取抑制剂，可用来研究神经系统疾病。
T16399	Opiranserin 化合物Opiranserin	1441000-45-8	98%
T16399	Opiranserin 是一种非阿片类和非 NSAID 镇痛候选药物，是 2 型甘氨酸转运蛋白 (GlyT2) 和 5-羟色胺受体 2A (5HT2A) 的双重拮抗剂，IC50分别为 0.86 和 1.3 μM。它可用于术后疼痛的研究，对 rP2X3 有拮抗作用，IC50为0.87 μM。
T10294	AM9405 化合物 T10294	T10294	98%
T10294	AM9405是一种新型的外周活性大麻素1型 (CB1)和5-羟色胺3型受体激动剂。 AM9405抑制回肠和结肠的抽搐收缩，IC50分别为45.71 和 0.076 nM。AM9405 在生理条件下显着减缓小鼠肠道蠕动.
T12843	SB-399885 hydrochloride 化合物 T12843	402713-81-9	98%
T12843	SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.
T16556	PNU-142633 化合物 T16556	187665-65-2	98%
T16556	PNU-142633 has anti-migraine efficacy. PNU-142633 is a high affinity and selective 5-HT1D receptor agonist (Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor...
T10611	Brexpiprazole S-oxide D8 化合物 T10611	2748605-29-8	98%
T10611	Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is...
T10344	AP521 化合物 T10344	151227-08-6	98%
T10344	AP521 is an agonist of the human 5-HT1A receptor (IC50: 94 nM).
TN1790	Isopteropodine 钩藤碱 E	5171-37-9	98%
TN1790	Isopteropodine (Uncarine E) 是从 Hamelia patens micropropagated 分离得到的一种异育亨宾型辛吲哚生物碱.具有抗菌活性，可刺激机体免疫系统。Isopteropodine 是 M1 型毒蕈碱乙酰胆碱 (muscarinic M1) 受体及 5-HT2 受体的正向调节剂...
T21360	Asenapine 阿塞那平	65576-45-6	98%
T21360	Asenapine (Org 5222) 是5-HT受体、肾上腺素受体、多巴胺受体和组胺受体拮抗剂，具有抗精神病作用，可用于治疗精神分裂症和与双相 1 型障碍相关的躁狂或混合发作。
T12631	(R)-Mirtazapine D3 化合物 T12631	T12631	98%
T12631	(R)-Mirtazapine D3 is a deuterium labeled (R)-Mirtazapine.(R)-Mirtazapine is a antagonist of 5-HT3 receptor.
T10267	Agomelatine (L(+)-Tartaric acid) 阿戈美拉汀 L(+)-酒石酸	824393-18-2	98%
T10267	Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and ...
T10498	5-HT2A antagonist 1 化合物 T10498	204643-75-4	98%
T10498	5-HT2A antagonist 1 is a 5-HT2A antagonist. It may be useful in the treatment of gastrointestinal disorders circulatory disorders.