核受体

核受体 (Nuclear Receptors) 是一类负责感应类固醇、甲状腺激素、维生素等分子的蛋白质。核受体对动物具有特异性，因此不存在于原生生物、藻类、真菌或植物中。人类中有47个核受体。这些细胞内受体与其他蛋白质一起调节特定基因的表达，从而控制生物体的发育、稳态和代谢。核受体与其他类别受体的区别在于它们对基因组DNA的直接控制。因此，这些受体被归类为转录因子。核受体对基因表达的调节通常发生在配体存在的情况下。配体与核受体的结合导致构象变化，激活受体。结果是基因表达的上调或下调。核受体在胚胎发育和成体稳态中都起着关键作用。

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Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-00762	ER alpha Protein, Human, Recombinant (His) ER alpha Protein, Human, Recombinant (His)	Human	E. coli
TMPJ-00762	Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of severa...
TMPY-02706	Vitamin D Receptor/VDR Protein, Human, Recombinant (His) Vitamin D Receptor/VDR Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
TMPY-02706	VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor), also known as NR1I1, belongs to the NR1I family, NR1 subfamily. It is composed of three domains: a modulati...
TMPY-02987	Vitamin D Receptor/VDR Protein, Mouse, Recombinant (His) Vitamin D Receptor/VDR Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
TMPY-02987	VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor), also known as NR1I1, belongs to the NR1I family, NR1 subfamily. It is composed of three domains: a modulati...
TMPY-06821	THRB Protein, Human, Recombinant (His) THRB Protein, Human, Recombinant (His)	Human	E. coli
TMPY-06821	Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation dom...
TMPY-06830	PPAR alpha/PPARA Protein, Human, Recombinant (His) PPAR alpha/PPARA Protein, Human, Recombinant (His)	Human	E. coli
TMPY-06830	Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in ...
TMPY-06837	PPAR alpha/PPARA Protein, Mouse, Recombinant (His) PPAR alpha/PPARA Protein, Mouse, Recombinant (His)	Mouse	E. coli
TMPY-06837	Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in ...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
TMPY-02575	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte diffe...