MMP

Matrix metallopeptidases (MMPs), also known as matrix metalloproteinases or matrixins, are metalloproteinases that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily.

Cat. No.	Product Name	CAS No.	Purity
T12539L	Prinomastat 普啉司他	192329-42-3	98%
T12539L	Prinomastat inhibits MMP-2, MMP-3 and MMP-9 (Kis: 0.05 nM, 0.3 nM and 0.26 nM, respectively). Prinomastat crosses the blood-brain barrier. It also has antitumor ...
T17201	UK 356618 化合物 T17201	230961-08-7	98%
T17201	UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).
TN4978	Scutellarein-7-O-glucoside 化合物 TN4978	26046-94-6	98%
TN4978	Scutellarein-7-O-glucoside inhibites MMP-2 activity.
TN1998	Notoginsenoside T5 三七皂苷T5	769932-34-5	98%
TN1998	Total panax notoginsenosides (TPNS) are the main active ingredients in San-Chi, the root of(Burk) F.H. Chen, which belongs to the Araliaceae family and has been ...
T16137	MRS1177 化合物 T16137	183721-13-3	98%
T16137	MRS1177 is an effective and selective antagonist of the human Adenosine A3 receptor (hA3AR) (Ki: 0.3 nM).
T13249	UK-370106 化合物 T13249	230961-21-4	98%
T13249	UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronecti...
T28985	TMI-1 化合物TMI-1	287403-39-8	98%
T28985	TMI-1 (WAY-171318) 是一种有效的抑制剂，用于抑制去整合素金属酶17 (ADAM17) 和其他基质金属蛋白酶MMPs。TMI-1 能够有效地抑制LPS 诱导的人原代单核细胞和人全血中TNF-α的分泌。TMI-1 在三阴性 (TN) 和过度表达ERBB2的乳腺肿瘤细胞系中选择性地诱导Caspase 依赖的细...
T10461	Batimastat sodium salt 化合物 T10461	130464-84-5	98%
T10461	Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).
TN4046	Excisanin A 化合物 TN4046	78536-37-5	98%
TN4046	ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
T14312	Apratastat 化合物 T14312	287405-51-0	98%
T14312	Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) an...
T16986	Tanomastat 化合物 T16986	179545-77-8	98%
T16986	Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 30...
TN5153	Torilin 窃衣素	13018-10-5	98%
TN5153	Torilin 是一种睾酮5α还原酶抑制剂，它（IC50=31.7+/-4.23μM）对5α还原酶的抑制作用强于α-亚麻酸（IC50=160.3+/-24.62μM），但弱于非那雄胺（IC50=0.38+/-0.06μM）。Torilin 具有免疫调节、肝脏保护和抗炎特性，它通过限制 TAK1介导的 MAP 激酶和 NF...
T1402	Fenofibric acid 非诺贝特酸	42017-89-0	99.94%
T1402	Fenofibric acid (FNF acid) 是 fenofibrate 的活性代谢物，是PPAR 激动剂，对 PPARα、PPARγ 和 PPARδ 的EC50值分别为 22.4、1.47 和 1.06 µM。它抑制COX-2的活性，IC50值为 48 nM。
T1592	Acetohydroxamic acid 乙酰氧肟酸	546-88-3	99.91%
T1592	Acetohydroxamic acid (N-Hydroxyacetamide) 是一种不可逆的细菌和植物尿素酶抑制剂，可研究慢性尿路感染。
T4082	Astragaloside 黄芪甲苷	17429-69-5	99.9%
T4082	Astragaloside 是黄芪中的主要活性成分之一。
T1687	Doxycycline 多西环素	564-25-0	99.88%
T1687	Doxycycline (Doxiciclina) 属于四环素类抗生素，是一种广谱的金属蛋白酶 (MMP) 抑制剂，具有口服活性。Doxycycline 具有抗菌活性和抗肿瘤活性。
T7044	Norepinephrine 去甲肾上腺素	51-41-2	99.84%
T7044	Norepinephrine (Levophed) 是β1选择性的肾上腺素能受体激动剂，EC50值为 5.37 μM。它可上调鼻咽癌肿瘤细胞中血管内皮生长因子、基质金属蛋白酶MMP-2和MMP-9的表达。
T3414	Morroniside 莫诺苷	25406-64-8	99.84%
T3414	Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用，可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T2993	Cordycepin 虫草素	73-03-0	99.78%
T2993	Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞中，剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。
T77617	MMP-9-IN-6 化合物MMP-9-IN-6	2241964-36-1	99.75%
T77617	MMP-9-IN-6 是一种 MMP-9 抑制剂，其 IC50 值为50 μM, 具有较好的抗溃疡功效。MMP-9-IN-6 具有潜在的抗肿瘤活性，可用于研究组织重塑、伤口修复和动脉粥样硬化。