TNF

Tumor necrosis factor (TNF, cachexin, or cachectin; once named as tumor necrosis factor alpha or TNFα) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNF is a member of the TNF superfamily, consisting of various transmembrane proteins with a homologous TNF domain.

Cat. No.	Product Name	CAS No.	Purity
TN3144	6,4'-Dihydroxy-7-methoxyflavanone 6,4'-二羟基-7-甲氧基二氢黄酮	189689-32-5	98%
TN3144	6,4'-Dihydroxy-7-methoxyflavanone 是一种从 Dalbergia odorifera T. Chen (Leguminosae) 的心材中分离出来的生物活性化合物，具有抗氧化、抗炎和神经保护作用。 6,4'-二羟基-7-甲氧基黄烷酮可用于治疗破骨性骨病如骨质疏松症、类风湿性关节炎和牙周病的...
TN2102	Procurcumenol 原莪述烯醇	21698-40-8	98%
TN2102	Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a).
TN4164	Grandifloroside 化合物 TN4164	61186-24-1	98%
TN4164	Grandifloroside shows good antioxidative and potent anti-inflammatory activities, it also exhibits potent inhibitory activity against TNF-α and 5α-reductase, sug...
TN4420	Latifolin 化合物 TN4420	10154-42-4	98%
TN4420	Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-ÎºB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
TN4490	Manassantin B 化合物 TN4490	88497-88-5	98%
TN4490	Manassantin B is a potent inhibitor of NF-ÎºB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-ÎºB. It also possesses anti-EBV ...
TN1882	Lucidenic acid D 赤芝酸D	98665-16-8	98%
TN1882	Lucidenic acid D2 is a nartural product from G. lucidum AF.
TN4146	Glutinol acetate 化合物 TN4146	6426-44-4	98%
TN4146	Glutinol acetate shows significant cytotoxic activity against four human cancer cell lines (HL-60, SK-OV-3, A549, and HT-29), with GI(50) in the range of 11.1-17...
TN1228	25S-Inokosterone 25S-牛膝甾酮	19595-18-7	98%
TN1228	25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2...
TN5019	Siegeskaurolic acid 化合物Siegeskaurolic acid	52645-97-3	98%
TN5019	Siegeskaurolic acid 是一种具有抗炎活性的天然产物。
TN3914	Echinatine 化合物 TN3914	480-83-1	98%
TN3914	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and...
TN4879	Questinol 化合物 TN4879	35688-09-6	98%
TN4879	Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit th...
TN4194	Heliangin 化合物 TN4194	13323-48-3	98%
TN4194	Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-ÎºB pathway on LPS-induced RAW 264.7 cells...
TN1354	Aaptamine 化合物Aaptamine	85547-22-4	98%
TN1354	Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
TN4334	Isotaxiresinol 化合物 TN4334	26194-57-0	98%
TN4334	Isotaxiresinol prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activa...
TMA2576	Episappanol 化合物 TMA2576	111254-18-3	98%
TMA2576	Episappanol has anti-inflammatory activity , it can significantly inhibit the secretion of the pro-inflammatory cytokines interleukin (IL-6) and tumor necrosis f...
TN1086	Dehydrotrametenolic acid 松苓新酸	6879-05-6	98%
TN1086	Dehydrotrametenolic acid (Dehydroeburicoic acid) 是从茯苓的菌核中分离的一种甾醇，具有抗肿瘤活性、抗炎和抗糖尿病作用。它通过 caspase-3途径诱导细胞凋亡。
TN4162	Goshonoside F5 化合物 TN4162	90851-28-8	98%
TN4162	Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
T38635	Kdo2-Lipid A ammonium Kdo2-Lipid A铵盐	1246298-62-3	98%
T38635	Kdo2-Lipid A ammonium (KLA）是一种具有选择性和有效性的 TLR4 激动剂，属于一种脂多糖。Kdo2-Lipid A ammonium 促使 TNF 和 PGE2 的释放。
T13175	TNF-α-IN-1 化合物TNF-α-IN-1	444287-49-4	98%
T13175	TNF-α-IN-1是 TNF-α 抑制剂。
TN3692	Conduritol A 化合物 TN3692	526-87-4	98%
TN3692	Conduritol A has a hypoglycemic effect, can have an effect on regulating the metabolism of blood lipid, free-radical scavenging, enhancing the antioxidant abilit...