ROS

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen (O2) produces superoxide (•O−2), which is the precursor of most other reactive oxygen species.In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis. However, during times of environmental stress (e.g., UV or heat exposure), ROS levels can increase dramatically.

Cat. No.	Product Name	CAS No.	Purity
TN3653	Cimidahurinine 化合物 TN3653	142542-89-0	98%
TN3653	Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity...
TMA0291	Dehydroglyasperin D 化合物 TMA0291	517885-72-2	98%
TMA0291	Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...
TN1241	3,8''-Biapigenin 化合物3,8'-Biapigenin	101140-06-1	98%
TN1241	3, 8''-Biapigenin can modulate intracellular ROS production.
TN4399	Kushenol C 化合物 TN4399	99119-73-0	98%
TN4399	Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2)....
TN3726	Cudraflavone B 化合物 TN3726	19275-49-1	98%
TN3726	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
TN3364	Agrimonolide 仙鹤草内酯	21499-24-1	98%
TN3364	Agrimonolide 是一种来自异香豆素的化合物，主要存在于草药Agrimonia pilosa Ledeb 中，具有显著的生物活性。Agrimonolide 通过抑制脂多糖（LPS）诱导的JAK-STATs 和p38 MAPKs 信号通路的激活而发挥抗炎作用。Agrimonolide 及其衍生物去甲阿戈莫内德已显示...
TN3872	Diosbulbin D 化合物 TN3872	66756-57-8	98%
TN3872	Diosbulbin D shows direct toxic effect on hepatocytes, the mechanism could be associated with oxidative stress.
TN1821	Kaempferol 3-O-arabinoside 山奈酚-3-O-α-L-吡喃阿拉伯糖苷	99882-10-7	98%
TN1821	Kaempferol-3-O-α±-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antioxid...
TN5264	Xanthoxyletin 化合物 TN5264	84-99-1	98%
TN5264	Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory ...
T5526	Glycoborinine 化合物 T5526	233279-39-5	98%
T5526	Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. Glycoborinine has photo-ac...
TN1910	Malvidin chloride 氯化锦葵色素	643-84-5	98%
TN1910	Malvidin chloride has anti-spermatogenic, and antioxidant activities. It can prevent endothelial dysfunction by inhibiting ROS and XO-1.
TN3517	Bisacurone 化合物 TN3517	120681-81-4	98%
TN3517	Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressi...
TN3614	Cearoin 化合物 TN3614	52811-37-7	98%
TN3614	Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...
TN4785	Picrasidine I 化合物 TN4785	100234-59-1	98%
TN4785	Picrasidine I has antiosteoclastogenic effect by inhibiting inflammation induced activation of MAPKs, NF-ÎºB and ROS generation followed by suppressing the gene ...
TN3655	Cimiside E 化合物 TN3655	154822-57-8	98%
TN3655	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
T22318	Taletrectinib 化合物DS-6051b	1505515-69-4	99.96%
T22318	Taletrectinib (AB-106) 是具有口服活力的、选择性的 ROS1/NTRK 抑制剂。它对重组 ROS1、NTRK1、NTRK2 和 NTRK3 有较强的抑制作用，IC50值分别为 0.207、0.622、2.28 和 0.98 nM。它还抑制 ROS1 G2032R 和其他抗 Crizotinib 的 ...
T0877	Gallic acid 没食子酸	149-91-7	99.95%
T0877	Gallic acid (Benzoic acid) 是一种天然多羟基酚类化合物，具有抑制环氧合酶-2 的自由基清除作用，还具有抗菌、抗氧化、抗菌、抗炎和抗肿瘤活性。
T3061	Lorlatinib 劳拉替尼	1454846-35-5	99.93%
T3061	Lorlatinib (PF-6463922) 是一种具有口服活性，选择性，脑渗透性和 ATP 竞争性的ROS1/ALK 抑制剂，具有抗癌活性。它对 ROS1、野生型 ALK 和 ALKL1196M 的Ki 值分别为 <0.025 nM、<0.07 nM 和 0.7 nM。
T4309	CIL56 化合物CIL56	300802-28-2	99.91%
T4309	CIL56 (CA3) 是一种选择性铁死亡诱导剂，可通过产生铁依赖性活性氧来诱导细胞铁死亡。
T1630	Tiopronin 硫普罗宁	1953-02-2	99.87%
T1630	Tiopronin (Acadione) 是可扩散的抗氧化剂，是重金属中毒的解毒剂和辐射防护剂。它可控制胱氨酸沉淀和排泄的速度，有用于胱氨酸尿症、类风湿性关节炎和肝病的研究潜力。