PARP

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes such as DNA repair, genomic stability, and programmed cell death.

Cat. No.	Product Name	CAS No.	Purity
TN2511	Britannilactone diacetate 化合物 TN2511	1286694-67-4	98%
TN2511	1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airwa...
TN1458	Buddlejasaponin IV 醉鱼草皂苷 Ⅳ	139523-30-1	98%
TN1458	Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-ka...
T16979	Talazoparib tosylate 化合物 T16979	1373431-65-2	98%
T16979	Talazoparib tosylate is a novel and potent PARP1/2 (n IC50: 0.57 nM for PARP1).
TN4999	Serratenediol 化合物 TN4999	2239-24-9	98%
TN4999	Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects be...
TN3619	Cedrusin 化合物 TN3619	75775-36-9	98%
TN3619	Cedrusin shows a cytotoxic effect on A375 and HeLa cells.
TN4340	Ivangustin 化合物 TN4340	14164-59-1	98%
TN4340	Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines.
TN4637	Neogrifolin 化合物 TN4637	23665-96-5	98%
TN4637	Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ...
T12366	PARP14 inhibitor H10 化合物 T12366	2084811-68-5	98%
T12366	PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
TN2106	Protodeltonin 化合物 TN2106	94992-08-2	98%
TN2106	Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhi...
TN4341	IVHD-valtrate 化合物 TN4341	28325-56-6	98%
TN4341	VHD-valtrate has anticancer effects against human ovarian cancer cells in vitro and in vivo, it is a potential therapeutic agent for ovarian cancer, providing a ...
TN3922	Effusanin E 化合物 TN3922	76470-15-0	98%
TN3922	Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
TN1139	Dehydrocavidine 岩黄连碱	83218-34-2	98%
TN1139	Dehydrocavidine (Dehydrocorydaline) 具有抗肿瘤活性，它通过诱导调节 Bax/Bcl-2 介导的细胞凋亡、激活半胱天冬酶以及切割 PARP 来抑制 MCF-7 细胞增殖。
TN3070	4beta-Hydroxywithanolide E 化合物 TN3070	54334-04-2	98%
TN3070	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progr...
TN1837	Kuguaglycoside C 化合物 TN1837	1041631-93-9	98%
TN1837	Kuguaglycoside C induces caspase-independent cell death, and is involved, at least in part, in the mechanism underlying cell necroptosis.
TN4028	Euchrestaflavanone B 化合物 TN4028	87402-91-3	98%
TN4028	Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanon...
TN4046	Excisanin A 化合物 TN4046	78536-37-5	98%
TN4046	ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
T5526	Glycoborinine 化合物 T5526	233279-39-5	98%
T5526	Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. Glycoborinine has photo-ac...
TN1728	Hellebrigenin 蟾蜍它里定	465-90-7	98%
TN1728	Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. H...
TN4271	Isochamaejasmine 异狼毒素	93859-63-3	98%
TN4271	Isochamaejasmine 分离自 S. chamaejasme L. 中分离出来，可抑制 NF-κB 活化。 Isochamaejasmine 通过抑制 Bcl-2 家族蛋白的活性诱导白血病细胞凋亡，可用于抗癌研究。
TN3614	Cearoin 化合物 TN3614	52811-37-7	98%
TN3614	Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...