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Search Results for " ki) "

Targets Recommended: Adenosine Receptor

2502

抑制剂 & 化合物

146

天然产物

84

重组蛋白

39

同位素

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Cat. No.	Product Name	Target	Signaling Pathways
T9238	KI-7	Adenosine Receptor	GPCR/G Protein; Neuroscience
	KI-7 是一种A2B 腺苷受体阳性变构调节剂。它增强选择性 A2B 腺苷受体激动剂 BAY 60-6583 和腺苷诱导的 cAMP 积累，EC50分别为 2390 nM 和 2550 nM。它也增强非选择性 A2B 腺苷受体激动剂 NECA 诱导的 cAMP 积累，EC50为 445.8 nM。
T11758L	KI696	Nrf2	Immunology/Inflammation
	KI696 是一种高亲和力探针，可有效抑制 Keap1 和 NRF2 的相互作用。
T2446	KI8751	EGFR; VEGFR; FGFR; PDGFR; c-Kit	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Ki8751 是一种有效的 VEGFR2 抑制剂，其 IC50=0.9 nM。
T11758	KI696 isomer	Nrf2	Immunology/Inflammation
	KI696 isomer 是 KI696 的异构体，是一种亲和力较低的探针，可用于研究免疫和代谢疾病。
T6347	Ki16198	LPA Receptor; LPL Receptor	GPCR/G Protein
	Ki16198 是一种可口服的 LPA 受体拮抗剂，是 Ki16425 的甲酯衍生物。它抑制 LPA1 和 LPA3 诱导的肌醇磷酸的Ki值分别为 0.34 和 0.93 μM，可用于胰腺癌发生和转移的研究。
T6108	Ki16425 Debio 0719	LPA Receptor; LPL Receptor	GPCR/G Protein
	Ki16425 (Debio 0719) 是一种竞争性、有效和可逆的 LPA1、LPA2 和 LPA3 拮抗剂，Ki 分别为 0.34、6.5 和 0.93 μM。它可抑制LPA 诱导的 HEK293A 细胞中 YAP/TAZ 的去磷酸化，降低LPA 诱导的 p42/p44 MAPK 激活。
T4315	Ki20227 N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲	c-Fms; VEGFR; CSF-1R; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Ki20227 是一种高效的、口服具有活性的、选择性的CSF1R(c-Fms 酪氨酸激酶)抑制剂，对 CSF1R，VEGFR2，c-Kit 和PDGFRβ的IC50分别为 2 nM，12 nM，451 nM 和 217 nM。它可以阻止破骨细胞分化和溶骨性破坏。
T68313	KI-328	Others	Others
	KI-328 is a novel KIT inhibitor. KI-328 shows selective potency against KIT kinase for the in vitro kinase assay, and inhibits the growth of wild-type (Wt)- and mutant-KIT-expressing cells, while it has little potency against D816V-KIT.
T69162	Ki23057	Others	Others
	Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treating drug-resistant gastric cancer cells, especially when used in combination with SN38, PTX, or VP16. The apoptosis process might be the main mechanism underlying the synergistic effect of these combinations. The ERCC1 and p53 genes may play an integral role in the synergism betwee...
T74402	FAP-PI3KI1	Others	Others
	FAP-PI3KI1 是一种成纤维细胞活化蛋白 (FAP) 靶向 PI3K 抑制剂，可选择性靶向表达 FAP 的人特发性肺纤维化 (IPF)细胞并有效抑制胶原蛋白合成，减少胶原蛋白沉积。
T15712	Laropiprant MK-0524	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Laropiprant (MK-0524) 是 DP receptor 的选择性拮抗剂，Ki 为 0.57 nM，对 TP 受体的 Ki 为 2.95 nM。
T5587	CGP71683 hydrochloride CGP71683A,盐酸CGP71683	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	CGP71683 hydrochloride (CGP71683A) 是竞争性的神经肽受体拮抗剂，Ki 值为 1.3 nM。
T4607	CAY 10465 CAY10465,CAY10465 Exclusive	AhR; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism
	CAY 10465 是一种选择性和高亲和力的芳香烃受体(AhR)激动剂，Ki 值为 0.2 nM。
T2373	Vipadenant CEB-4520,BIIB-014	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Vipadenant (CEB-4520) 是一种腺苷受体拮抗剂，抑制 A2A 和 A1 活性的 Ki 值分别为 1.3 和 68 nM。
T10261	AGN 196996	Others; Retinoid Receptor; Autophagy	Autophagy; Metabolism; Others
	AGN 196996是一种高效且具有选择性的RARα抑制剂（Ki：2 nM）。AGN 196996对RARβ和RARγ的亲和性极低，Ki 分别为1087 nM 和8523 nM。
TQ0084	lumateperone Tosylate ITI-007,Lumateperone甲苯磺酸盐	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	lumateperone Tosylate (ITI-007) 是5-HT 2A 受体拮抗剂，Ki 为 0.54 nM，突触前 D2受体的部分激动剂和突触后 D2受体的拮抗剂，Ki 为 32 nM。
T15682	L-371,257	Oxytocin Receptor; Vasopressin Receptor	Endocrinology/Hormones; GPCR/G Protein
	L-371,257 是催产素受体的竞争性拮抗剂，pA2 为 8.4，Ki 为 19 nM。 L-371,257 对加压素受体 1a 的 Ki 值为 3.7 nM。
T27800	LAS38096 LAS 38096,LAS-38096	Adenosine Receptor	GPCR/G Protein; Neuroscience
	LAS38096 是一种A2B 腺苷受体拮抗剂（Ki ：17 nM），具有强效性、选择性和高效性。
T23782	Benzolamide CL-11366,W 1803,CL 11366,CL11366,苯唑拉胺,W-1803	Carbonic Anhydrase	Metabolism
	Benzolamide (CL 11366) 是碳酸酐酶 (CA) 抑制剂，抑制hCA I(Ki:15 nM)、hCA II(Ki:9 nM)、EcoCAγ(Ki:94 nM)、VchCAγ(Ki:78 nM)、CAS3(Ki:54 nM)。它可用于研究青光眼和癫痫。
T39284	EST73502 HCl	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	EST73502 是 μ-阿片受体激动剂 (Ki = 64 nM) 激动剂和 σ1 受体拮抗剂 (Ki = 118 nM)。 EST73502 显示出镇痛活性。
T41247	Thioperamide maleate MR-12842 maleate,硫丙咪胺马来酸	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Thioperamide maleate (MR-12842 maleate) 是一种有效且选择性的 H3 受体拮抗剂 (Ki = 4.3 nM)，可抑制 [3H]histamine 的合成 (Ki = 31 nM)。
T15595L	IRL-1620 acetate IRL-1620 acetate（142569-99-1 free base）	Endothelin Receptor	GPCR/G Protein
	IRL-1620 acetate 是一种有效的特异性内啡肽 B 受体 (ETB) 激动剂，Ki 为 16 pM，相比于ETA，其Ki 为 19 μM。
T14069	A-3 hydrochloride	CaMK; Casein Kinase; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Neuroscience; Stem Cells; Tyrosine Kinase/Adaptors
	A-3 hydrochloride 是一种细胞可渗透的、可逆的、ATP 竞争性非选择性拮抗剂。它抑制 PKA 、酪蛋白激酶 II 和肌球蛋白轻链激酶，Ki 值分别为4.3 µM、5.1 µM 和7.4 µM。它还抑制 PKC 和酪蛋白激酶 I 的活性，Ki 分别为 47 µM 和 80 µM。
T15270	Fananserin RP 62203,法南色林	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Fananserin 是一种有效的、特异性的、口服活性的 5-HT2 拮抗剂（大鼠 5-HT2A 的 Ki = 0.37 nM）。 Fananserin 是人 D4 受体的拮抗剂 (Ki = 2.93 nM)。
T2420	PHT-427 PHT 427,CS-0223	Apoptosis; Akt; PDK	Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	PHT-427 (CS-0223) 是一种 Akt 和 PDPK1双重抑制剂，与 Akt 和 PDPK1 中的 PH 结构域有亲和性，Ki 分别为 2.7 μM 和 5.2 μM。
T1749	AL 082D06 D-06,AL082D06	Glucocorticoid Receptor	Endocrinology/Hormones
	AL 082D06 (D-06) 是非甾体类糖皮质激素受体 (GR) 选择性拮抗剂(Ki:210 nM)。
T1865	S1RA E-52862,4-(2-((5-甲基-1-(2-萘基)-1H-吡唑-3-基)氧基)乙基)吗啉	Sigma receptor	GPCR/G Protein
	S1RA (E-52862) 是一种有效且特异性的 sigma-1受体拮抗剂，Ki 为17nM，对 σ2R 具有良好的选择性，Ki 值大于 1000 nM。
T37696	NOS1-IN-1 nNOS Inhibitor I	NOS	Immunology/Inflammation
	NOS1-IN-1（nNOS Inhibitor I）是一种强效、选择性和细胞渗透性 nNOS 抑制剂（Ki：120 nM）。NOS1-IN-1 对 eNOS 的 Ki 值为 39 μM，对 iNOS 的 Ki 值为 325 μM。
T7343	PF-04979064	PI3K; mTOR	PI3K/Akt/mTOR signaling
	PF-04979064 是一种选择性 PI3K/mTOR 双重激酶抑制剂，能够抑制 PI3Kα (Ki=0.13 nM) 和 mTOR (Ki=1.42 nM)。
T28531	Facinicline hydrochloride RG3487	5-HT Receptor; AChR	GPCR/G Protein; Neuroscience
	Facinicline hydrochloride (RG3487) 是一种口服有效的烟碱α7 receptor 部分激动剂，对人 nAChR 的 Ki 值为 6 nM。它可改善啮齿类动物的认知和感觉运动门控。它与5-HT3受体结合的 Ki 为 1.2 nM。
T2017	U-104 NSC-213841,MST-104	Carbonic Anhydrase	Metabolism
	U-104 (NSC-213841) 是 CA IX 和 CA XII 碳酸酐酶 (CA) 抑制剂，其 Ki 分别为 45.1 nM 和 4.5 nM。小鼠模型中，它能够表现出明显的抑制肿瘤生长的作用。
T12306	OMDM-5	Cannabinoid Receptor; Endogenous Metabolite; TRP/TRPV Channel	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
	OMDM-5 是有效的、选择性的anandamide 细胞摄取抑制剂，Ki 为 4.8 μM。它是VR1 (TRPV1)激动剂，EC50为 75 nM，显示出对大麻素 1 型受体 (CB1) 的弱配体活性 (Ki=4.9 μM)。
T14151	AKR1C1-IN-1	NADPH	Metabolism
	AKR1C1-IN-1 是高选择性 AKR1C1抑制剂(Ki:4 nM)。
T35347	Et-29 NRD167	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Et-29 是一种特异性的 SIRT5 抑制剂，Ki 为 40 nM。
T2009	SB-3CT	MMP	Proteases/Proteasome
	SB-3CT 是一种可透过血脑屏障的、竞争性的金属蛋白酶MMP-2和MMP-9抑制剂，Ki 分别为 13.9 nM、600 nM。他对明胶酶具有高选择性。它具有神经保护和抗癌作用。
T15811	LY2955303	Others; Retinoid Receptor	Metabolism; Others
	LY2955303 是一种有效的特异性视黄酸受体 γ 拮抗剂（RARγ，Ki = 1.09 nM）。
T11799	L-745870 hydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	L-745870 hydrochloride 是可透过血脑屏障的、选择性的、具有口服活性的多巴胺 D4受体拮抗剂，Ki=0.43 nM。它对 D2(Ki 为 960 nM) 和 D3(Ki 为 2300 nM) 受体的亲和力相对较弱，对 5-HT2受体，sigma 位点和 α-肾上腺素受体表现出中等亲和力。
T0713	Drofenine hydrochloride 盐酸六氢芬宁,Hexahydroadiphenine hydrochloride	AChE	Neuroscience
	Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) 是竞争性胆碱酯酶抑制剂，ki=3 uM。
T37793	A2B receptor antagonist 2 A2B receptor antagonist 2	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2B receptor antagonist 2 是腺苷受体 A2B 的拮抗剂（rA1 的 Ki = 2.30 μM，rA2A 的 Ki = 6.8 μM，hA2B 的 3.44 μM）。
T2688	LY310762 LY310762 HCl	5-HT Receptor	GPCR/G Protein; Neuroscience
	LY310762 是 5-HT1D 受体拮抗剂，Ki 为 249 nM。
T8419	XP-59	SARS-CoV	Microbiology/Virology
	XP-59 是一种 SARS-CoV Mpro 抑制剂，其 Ki 值为 0.1 nM。
T12911	Sigma-1 receptor antagonist 2	Sigma receptor	GPCR/G Protein
	Sigma-1 receptor antagonist 2 是有效的sigma 1受体选择性拮抗剂，与 σ1 和 σ2 受体结合的Ki 分别为 3.88 和 1288 nM。
TP1957L	PKI (5-24) Acetate(99534-03-9 free base)	PKA	Tyrosine Kinase/Adaptors
	PKI (5-24) Acetate(99534-03-9 free base) 是一种高亲和力 PKA 抑制剂 (Ki = 2.3 nM)。
T5047	PD-168077 maleate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	PD-168077 maleate 是多巴胺 D4受体选择性激动剂，其 Ki=9 nM。
T7292	FITM 4-氟-N-[4-[6-(异丙基氨基)嘧啶-4-基]-1,3-噻唑-2-基]-N-甲基苯甲酰胺	GluR	Neuroscience
	FITM 是mGlu1受体的一种负变构调节剂，Ki 值为2.5 nM。
T6022	LY404039 pomaglumetad	Glucocorticoid Receptor; GluR	Endocrinology/Hormones; Neuroscience
	LY404039 (pomaglumetad) 是可口服的mGluR2和mGluR3选择性激动剂，有抗精神病和抗焦虑的作用。它对重组人mGluR2和mGluR3的Ki 分别为 149 和 92 nM，比对其他受体/转运蛋白的抑制性高 100 倍以上。
T5484	GSK467	Histone Demethylase; Histone Methyltransferase	Chromatin/Epigenetic
	GSK467 是一种有效的、选择性的 KDM5 (JARID1) 抑制剂，Ki 值为10 nM。
T22959	m-Chlorophenylbiguanide hydrochloride 1-(3-Chlorophenyl)biguanidehydrochloride,1-(3-氯苯基)双胍	5-HT Receptor	GPCR/G Protein; Neuroscience
	m-Chlorophenylbiguanide hydrochloride 是一种 5-HT3 受体激动剂。它选择性结合 5-HT3(Ki: 0.002 µM) 超过 5-HT1A(Ki: 10 µM) 和 5-HT2(Ki: 10 µM) 受体，但也结合多巴胺转运蛋白上的高亲和力和低亲和力位点( DAT；IC50：在大鼠尾状壳核突触体膜中分别为 0.4 和 34.8 µM）。
T10691	CAY10595	GPR	Endocrinology/Hormones; GPCR/G Protein
	CAY10595 是 CRTh2 (DP2) 受体的拮抗剂，Ki 为 10 nM。
T14927	Centrinone LCR-263	PLK; Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Centrinone (LCR-263) 是 polo 样激酶 4 的可逆抑制剂，对PLK4的Ki 值为0.16 nM。

化合物

Cat.No: T9238

Target: Adenosine Receptor

Cat.No: T11758L

Target: Nrf2

Cat.No: T2446

Target: EGFR, VEGFR, FGFR, PDGFR, c-Kit

Cat.No: T11758

Target: Nrf2

Cat.No: T6347

Target: LPA Receptor, LPL Receptor

Cat.No: T6108

Synonym: Debio 0719

Target: LPA Receptor, LPL Receptor

Cat.No: T4315

Synonym: N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲

Target: c-Fms, VEGFR, CSF-1R, PDGFR, c-Kit

Cat.No: T68313

Target: Others

Cat.No: T69162

Target: Others

Cat.No: T74402

Target: Others

Cat.No: T15712

Synonym: MK-0524

Target: Prostaglandin Receptor

CGP71683 hydrochloride

Cat.No: T5587

Synonym: CGP71683A,盐酸CGP71683

Target: Neuropeptide Y Receptor

Cat.No: T4607

Synonym: CAY10465,CAY10465 Exclusive

Target: AhR, Aryl Hydrocarbon Receptor

Cat.No: T2373

Synonym: CEB-4520,BIIB-014

Target: Adenosine Receptor

Cat.No: T10261

Target: Others, Retinoid Receptor, Autophagy

lumateperone Tosylate

Cat.No: TQ0084

Synonym: ITI-007,Lumateperone甲苯磺酸盐

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T15682

Target: Oxytocin Receptor, Vasopressin Receptor

Cat.No: T27800

Synonym: LAS 38096,LAS-38096

Target: Adenosine Receptor

Cat.No: T23782

Synonym: CL-11366,W 1803,CL 11366,CL11366,苯唑拉胺,W-1803

Target: Carbonic Anhydrase

Cat.No: T39284

Target: Opioid Receptor

Thioperamide maleate

Cat.No: T41247

Synonym: MR-12842 maleate,硫丙咪胺马来酸

Target: Histamine Receptor

IRL-1620 acetate

Cat.No: T15595L

Synonym: IRL-1620 acetate（142569-99-1 free base）

Target: Endothelin Receptor

A-3 hydrochloride

Cat.No: T14069

Target: CaMK, Casein Kinase, PKA, PKC

Cat.No: T15270

Synonym: RP 62203,法南色林

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T2420

Synonym: PHT 427,CS-0223

Target: Apoptosis, Akt, PDK

Cat.No: T1749

Synonym: D-06,AL082D06

Target: Glucocorticoid Receptor

Cat.No: T1865

Synonym: E-52862,4-(2-((5-甲基-1-(2-萘基)-1H-吡唑-3-基)氧基)乙基)吗啉

Target: Sigma receptor

Cat.No: T37696

Synonym: nNOS Inhibitor I

Target: NOS

Cat.No: T7343

Target: PI3K, mTOR

Facinicline hydrochloride

Cat.No: T28531

Synonym: RG3487

Target: 5-HT Receptor, AChR

Cat.No: T2017

Synonym: NSC-213841,MST-104

Target: Carbonic Anhydrase

Cat.No: T12306

Target: Cannabinoid Receptor, Endogenous Metabolite, TRP/TRPV Channel

Cat.No: T14151

Target: NADPH

Cat.No: T35347

Synonym: NRD167

Target: Sirtuin

Cat.No: T2009

Target: MMP

Cat.No: T15811

Target: Others, Retinoid Receptor

L-745870 hydrochloride

Cat.No: T11799

Target: Dopamine Receptor

Drofenine hydrochloride

Cat.No: T0713

Synonym: 盐酸六氢芬宁,Hexahydroadiphenine hydrochloride

Target: AChE

A2B receptor antagonist 2

Cat.No: T37793

Synonym: A2B receptor antagonist 2

Target: Adenosine Receptor

Cat.No: T2688

Synonym: LY310762 HCl

Target: 5-HT Receptor

Cat.No: T8419

Target: SARS-CoV

Sigma-1 receptor antagonist 2

Cat.No: T12911

Target: Sigma receptor

PKI (5-24) Acetate(99534-03-9 free base)

Cat.No: TP1957L

Target: PKA

PD-168077 maleate

Cat.No: T5047

Target: Dopamine Receptor

Cat.No: T7292

Synonym: 4-氟-N-[4-[6-(异丙基氨基)嘧啶-4-基]-1,3-噻唑-2-基]-N-甲基苯甲酰胺

Target: GluR

Cat.No: T6022

Synonym: pomaglumetad

Target: Glucocorticoid Receptor, GluR

Cat.No: T5484

Target: Histone Demethylase, Histone Methyltransferase

m-Chlorophenylbiguanide hydrochloride

Cat.No: T22959

Synonym: 1-(3-Chlorophenyl)biguanidehydrochloride,1-(3-氯苯基)双胍

Target: 5-HT Receptor

Cat.No: T10691

Target: GPR

Cat.No: T14927

Synonym: LCR-263

Target: PLK, Aurora Kinase

Cat. No.	Product Name	Target	Signaling Pathways
T2922	Phlorizin Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin	ATPase; SGLT	GPCR/G Protein; Membrane transporter/Ion channel
	Phlorizin (Phloridzin) 是非选择性的SGLT 抑制剂，也是Na+/K+-ATPase 抑制剂，对于hSGLT1和hSGLT2的Ki 值分别为 300 和 39 nM。
T4S2354	Dimethylfraxetin 二甲基白蜡树亭,Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin	Carbonic Anhydrase	Metabolism
	Dimethylfraxetin (6,7,8-Trimethoxycoumarin) 是Carbonic anhydrase 抑制剂(Ki:0.0097 μM)。
T8182	Guanfu base A Guan-fu base A,关附甲素	P450; Potassium Channel; HER	Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Tyrosine Kinase/Adaptors
	Guanfu base A 是一种生物碱，分离自 Aconitum coreanum，是非竞争性 CYP2D6抑制剂，对人肝微粒体 (HLM) 的 Ki 为 1.20 μM，对人重组体 (rCYP2D6) 的 Ki 为 0.37 μM。它也是 CYP2D 的有效竞争抑制剂。它还能抑制 HERG 通道电流。Guan-fu base A 具有抗心律失常的作用。
T8260	4',5-Dihydroxyflavone	Lipoxygenase; Glucosidase	Metabolism
	4',5-Dihydroxyflavone 是大豆 LOX-1，Ki=102.6 μM。它也是一种酵母 α-葡萄糖苷酶抑制剂，IC50=66 μM。
TN5752	Isorhapontin	Antifungal	Microbiology/Virology
	Isorhapontin 抑制木霉属纤维二糖水解酶 I (Ki = 57.2 μM) 和木霉属内切葡聚糖酶 I 的活性。Isorhapontin 具有抗真菌活性。
T9605	Sangivamycin BA-90912,桑霉素,NSC 65346	Nucleoside Antimetabolite/Analog; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
	Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。
T2209	Serotonin hydrochloride 5-HT hydrochloride,5-羟基色胺盐酸盐,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride	5-HT Receptor; Endogenous Metabolite; Transferase	GPCR/G Protein; Metabolism; Neuroscience
	Serotonin hydrochloride (Serotonin HCl) 是一种内源性 5-HT 受体激动剂、CNS 中的单胺神经递质和儿茶酚 O-甲基转移酶 (COMT) 抑制剂，Ki 值为 44 μM。
T15686	L-741626 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole	Dopamine Receptor	GPCR/G Protein; Neuroscience
	L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) 是D2多巴胺受体选择性拮抗剂，对人 D2、D3 和 D4 受体的Ki 分别为 2.4、100 和 220 nM。
T6396	(R)-(-)-Gossypol acetic acid (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate	BCL; Autophagy	Apoptosis; Autophagy
	(R)-(-)-Gossypol acetic acid (AT101 acetate) 是天然产物 Gossypol 的左旋异构体，与 Bcl-2、Bcl-xL 和 Mcl-1 结合，Ki 为 0.32 μM、0.48 μM 和 0.18 μM。
T4429	Rauwolscine hydrochloride Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂，Ki=12 nM。
TN1160	1,2,3,6-Tetragalloylglucose 1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG	LDL; UGT	Metabolism
	1,2,3,6-Tetragalloylglucose (TeGG) 是 UDP-葡萄糖醛酸转移酶 1 家族成员，是多肽A1 的抑制剂(Ki:1.68 μM)。
T8373	6-Diazo-5-oxo-L-nor-Leucine DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine	Influenza Virus; Glutaminase; Antibacterial; Antibiotic	Microbiology/Virology; Proteases/Proteasome
	6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) 是一种谷氨酰胺拮抗剂，具有抗菌、抗病毒和抗癌作用，其Ki 值为 6 μM。它能降低肿瘤细胞的自我更新能力和转移能力，在体外表现出遗传毒性。
TN1472	Cassiaside	Beta-Secretase; BACE	Neuroscience
	Cassiaside 是一种萘甲酮糖苷，抑制 BACE1 (IC50= 4.45 μM; Ki=9.85 μM)。Cassiaside 对半乳糖胺损伤具有明显的肝脏保护作用，具有潜在的抗阿尔茨海默病 (AD) 活性。
T5648	Purpurin 吡啉,1,2,4-Trihydroxyanthraquinone,Hydroxylizaric acid,Verantin	MAO; Antibacterial; Antibiotic; Antifungal	Metabolism; Microbiology/Virology; Neuroscience
	Purpurin (Verantin) 是来自Rubia tinctorumL. 的天然蒽醌，具有抗抑郁样作用。
T0687	Simvastatin 辛伐他汀,MK-0733,MK 733	Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM)，具有口服活性。Simvastatin 具有降血脂活性，可以抑制肝脏产生胆固醇，还可以用于预防心血管疾病。
TN1016	Kukoamine A	NF-κB; Lipoxygenase; DNA/RNA Synthesis; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB
	Kukoamine A 是一种天然的精胺衍生物，具有抗癌、抗高血压、细胞保护、抗氧化和抗炎活性。它是锥虫硫磷还原酶抑制剂，Ki 值为 1.8 μM。
T6856	Halofuginone 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110	Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Stem Cells
	Halofuginone (RU-19110) 是Febrifugine 的衍生物，是一种竞争性脯氨酰-tRNA 合成酶抑制剂。它也是肺血管扩张剂，可激活Kv 通道并阻断电压门控、受体操作和存储操作的钙离子通道。它具有抗炎、抗癌、抗疟疾和抗纤维化作用。
TN1120	Osthenol	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Osthenol 是一种前酰化香豆素，从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用，IC50=0.74 µM，对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
T10941	D-Ribonolactone D-(+)-核糖酸-1,4-内酯,D-核糖内酯	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Ribonolactone 是一种大肠杆菌 β-半乳糖苷酶的抑制剂，Ki 为 26 mM。它也一种糖内酯。
TN3013	4,5-Dimethoxycanthin-6-one Methylnigakinone	P450; Antibacterial; PDE	Metabolism; Microbiology/Virology
	4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂（IC50 ： 1.7 μM, Ki ： 2.6 μM），对环磷酸腺苷（cAMP）磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性，对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。
T7481	2-Hydroxycaprylic acid 2-hydroxyoctanoic acid,2-羟基辛酸	Others	Others
	2-Hydroxyoctanoic acid 是中链酰基辅酶 A 合成酶抑制剂 (Ki:500 μM)。
T4000	(±)-Equol Equol,(±)-雌马酚,(R,S)-Equol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。
TN1736	Hibifolin 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷	Adenosine deaminase	Metabolism
	Hibifolin 是一种黄酮醇糖苷，是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。
T5081	Adenine monohydrochloride hemihydrate 腺嘌呤盐酸盐,Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate	Endogenous Metabolite; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Adenine monohydrochloride hemihydrate 是内源性代谢产物的一种。
TQ0296L	N-Nornuciferine hydrochloride(4846-19-9 free base) N-Nornuciferine hydrochloride	P450	Metabolism
	N-Nornuciferine hydrochloride(4846-19-9 free base) (N-Nornuciferine hydrochloride) 是荷叶中的一种 aporphine 生物碱，显着抑制 CYP2D6（IC50：3.76 μM，Ki：2.34 μM）。
T6430	Calcifediol 25-羟基维生素 D3,U 32070E,25-hydroxy Vitamin D3,RO 8-8892,骨化二醇	Endogenous Metabolite	Metabolism
	Calcifediol (U 32070E) 是由维生素 D3 在肝中经羟基化后得到的前激素，是 VDR 的有效抑制剂。
TN1849	Kuwanon H	GPR; Bombesin Receptor	Endocrinology/Hormones; GPCR/G Protein
	Kuwanon H 是分离自桑白皮的黄酮类化合物，具有拮抗非肽类蛙皮素受体的活性。Kuwanon H 特异性抑制细胞内胃泌激素释放肽 CRP 与GRP-preferring 受体的结合，Ki 为 290 nM。
TN3748	D-Asparagine D-天冬酰胺,H-D-Asn-OH	Others; Endogenous Metabolite	Metabolism; Others
	D-Asparagine (H-D-Asn-OH) 是酵母菌株的氮源。 D-Asparagine 是 L-Asparagine 水解的竞争性抑制剂 (Ki = 0.24 mM)。
T10191L	7-Chlorokynurenic acid 7-chloro-4-hydroxy-2-carboxyquinoline,7-氯犬尿酸,7-CKA	GluR; NMDAR	Neuroscience
	7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) 是一种有效的选择性 NMDA 受体拮抗剂，对甘氨酸 B 激动剂位点的 IC50 为 0.56 μM。 7-Chlorokynurenic acid 抑制谷氨酸再摄取到突触小泡中，Ki 为 0.59 μM，并在神经轴输送后显示出镇痛作用。
TN1982	Neoglycyrol	Others	Others
	Neoglycyrol 是分离自甘草的根中的化合物。它是由传统专利药通脉养心丸中筛选得到，具有潜在心肌保护作用。
T5244	Aminomalonic acid 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate	Others; Endogenous Metabolite	Metabolism; Others
	Aminomalonic acid 是氨基内源性代谢产物，在体外能作为来源 Leukemia 5178Y/AR 和小鼠胰腺的L- 天冬酰胺合成酶的高效抑制剂 (Leukemia 5178Y/AR:Ki= 0.0023 M，小鼠胰腺:Ki= 0.0015 M)。它有潜力用作区分黑素瘤转移的不同阶段生物标志物。
T2926	Schizandrin A	P450; Virus Protease; Autophagy	Autophagy; Metabolism; Microbiology/Virology
	Schisandrin A 是一种从东方药物五味子中提取的主要有效成分，抑制 CYP3A 活性，IC50 分别为 6.60 μM 和 Ki 为 5.83 μM。
TN1650	Friedelin 软木三萜酮,无羁萜	P450; NOS; Caspase; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Proteases/Proteasome
	Friedelin 是分离自 Maytenus ilicifolia(Mart) 的叶子。它是 CYP3A4的非竞争性抑制剂，其 IC50和 Ki 分别为10.79 μM 和 6.16 μM，也是 CYP2E1的竞争性抑制剂，其 IC50和 Ki 分别为 22.54 μM 和 18.02 μM。
T2770	Gentiopicroside Gentiopicrin,龙胆苦甙,龙胆苦苷	P450; HCV Protease	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Gentiopicroside (Gentiopicrin) 是天然环烯醚萜苷，具有抗炎和抗氧化活性。它抑制P450的活性，对 CYP2A6 的 IC50和 Ki 值分别为 61 µM 和 22.8 µM，
T3149	Salvianolic Acid C 丹酚酸C,丹酚酸 C	Others; P450	Metabolism; Others
	Salvianolic acid C 属于天然产物，是一种细胞色素 P4502C8(CYP2C8) 和细胞色素 P4502J2(CYP2J2) 的抑制剂 (Ki=4.82/5.75 μM)，具有非竞争性。Salvianolic Acid C 具有抗新冠病毒活性。
T13539	Allopurinol riboside	Others; Endogenous Metabolite; Parasite; Drug Metabolite	Metabolism; Microbiology/Virology; Others
	Allopurinol riboside 是别嘌醇的代谢产物，具有抗寄生虫作用。 Allopurinol riboside 竞争性抑制嘌呤核苷磷酸化酶对肌苷的作用，Ki 为 277 μM。
TN1800	Isosakuranin	Others	Others
	Isosakuranin 是一种提取自Paliurus ramosissimus果实中的天然产物,具有抗糖尿病作用。
T2144	Tacrolimus 他克莫司,Fujimycin,FK506,FR900506	Phosphatase; Others; Antibacterial; Antibiotic; mTOR; Autophagy	Autophagy; Metabolism; Microbiology/Virology; Others; PI3K/Akt/mTOR signaling
	Tacrolimus (Fujimycin) 属于大环内酯类抗生素，可以与 FKBP12 结合形成高亲和力复合物 (Ki=0.2 nM)，抑制钙/钙调蛋白依赖性蛋白磷酸酶的活性。Tacrolimus 是一种免疫抑制剂，通过抑制 IL-2 的释放，全面抑制 T 淋巴细胞的作用。
T5564	Tricarballylic acid β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸	aconitase; Mitochondrial Metabolism	Metabolism
	Tricarballylic acid (Carballylic acid) 是三碳烯丙酸酯的共轭酸，是一种乌头酸水合酶的竞争性抑制剂，其 Ki= 0.52 mM。
T5568	H-Tyr(3-I)-OH 3-碘-L-酪氨酸,3-Iodo-L-tyrosine	Endogenous Metabolite	Metabolism
	H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) 是酪氨酸羟化酶抑制剂和甲状腺激素的中间体。
T6323	Oligomycin A MCH 32,寡霉素A	ATPase; Antibiotic; Antifungal	Membrane transporter/Ion channel; Microbiology/Virology
	Oligomycin A (MCH 32) 属于天然产物，是一种线粒体 F0F1-ATPase 抑制剂 (Ki=1 μM)。Oligomycin A 可以抑制线粒体氧化磷酸化，诱导细胞凋亡。Oligomycin A 具有抗真菌活性。
T14853	Cabergoline FCE-21336,卡麦角林	Dopamine Receptor; 5-HT Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Cabergoline (FCE-21336) 是一种麦角衍生的多巴胺 D2亚类受体激动剂，高亲和力作用于D2、D3和5-HT2B 受体，Ki 分别为 0.7、1.5 和 1.2。
T7671	Myosmine 麦司明,麦斯明	Others; AChR	Neuroscience; Others
	Myosmine 是存在于木贼中的一种烟草生物碱，对 a4b2 烟碱乙酰胆碱受体具有低亲和力，Ki 值为 3300 nM。
T4024	Norharmane 2-Azacarbazole,2,9-Diazafluorene,β-Carboline,去甲哈尔满	DNA; Endogenous Metabolite; Monoamine Oxidase	DNA Damage/DNA Repair; Metabolism; Neuroscience
	Norharmane (β-Carboline) 是一种有效的选择性单胺氧化酶 A (MAO-A) 抑制剂，Ki=3.34 μM。
T5S0669	Bergamottin 5-Geranoxypsoralen,Bergamotine,Bergaptin,佛手柑素	P450	Metabolism
	Bergamottin (5-Geranoxypsoralen) 是竞争性CYP1A1抑制剂(Ki:10.703 nM)。
T2O2744	alpha-Naphthoflavone 苯并黄素；α-萘黄酮；7,8-苯并黄酮,7,8-benzoflavone,α-萘黄酮	Aromatase	Endocrinology/Hormones
	alpha-Naphthoflavone (7,8-benzoflavone) 是合成的黄酮类化合物，是一种竞争性芳香酶抑制剂，其IC50=0.5 μM，Ki=0.2 μM。
TN2268	Tetrahydromagnolol	Cannabinoid Receptor; GPR; GABA Receptor	Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Tetrahydromagnolol 是 Magnolol 的主要代谢产物，是一种弱的GPR55受体拮抗剂。它是选择性大麻素CB2受体激动剂，EC50为 170 nM，Ki 为 416 nM，对CB2受体的选择性比 CB1 受体高 20 倍。
T5S0994	N-Methylcytisine N-甲基野靛碱,Caulophylline	Others; AChR	Neuroscience; Others
	N-Methylcytisine (Caulophylline) 是苦参中的一种三环喹啉类生物碱，具有降血糖、缓解疼痛和抗炎活性。它是中枢神经系统中乙酰胆碱烟碱受体的选择性配体，对鱿鱼视神经节中的烟碱乙酰胆碱受体具有很高的亲和力，Kd 为 50 nM。
T1310	2-Thiouracil Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶	Thyroid hormone receptor(THR); NO Synthase	Endocrinology/Hormones; Immunology/Inflammation
	2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM)，是一种抗甲状腺化合物，可用作高度特异性的黑色素瘤探测物。
T4S0051	Coptisine sulfate	Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Coptisine Sulfate 是一种从黄连中分离到的生物碱，是非竞争性的IDO 抑制剂，Ki=为 5.8 μM，IC50=6.3 μM。
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天然产物

Cat.No: T2922

Synonym: Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin

Target: ATPase, SGLT

Dimethylfraxetin

Cat.No: T4S2354

Synonym: 二甲基白蜡树亭,Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin

Target: Carbonic Anhydrase

Cat.No: T8182

Synonym: Guan-fu base A,关附甲素

Target: P450, Potassium Channel, HER

4',5-Dihydroxyflavone

Cat.No: T8260

Target: Lipoxygenase, Glucosidase

Cat.No: TN5752

Target: Antifungal

Cat.No: T9605

Synonym: BA-90912,桑霉素,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

Serotonin hydrochloride

Cat.No: T2209

Synonym: 5-HT hydrochloride,5-羟基色胺盐酸盐,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride

Target: 5-HT Receptor, Endogenous Metabolite, Transferase

Cat.No: T15686

Synonym: 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole

Target: Dopamine Receptor

(R)-(-)-Gossypol acetic acid

Cat.No: T6396

Synonym: (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate

Target: BCL, Autophagy

Rauwolscine hydrochloride

Cat.No: T4429

Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Target: Adrenergic Receptor

1,2,3,6-Tetragalloylglucose

Cat.No: TN1160

Synonym: 1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG

Target: LDL, UGT

6-Diazo-5-oxo-L-nor-Leucine

Cat.No: T8373

Synonym: DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine

Target: Influenza Virus, Glutaminase, Antibacterial, Antibiotic

Cat.No: TN1472

Target: Beta-Secretase, BACE

Cat.No: T5648

Synonym: 吡啉,1,2,4-Trihydroxyanthraquinone,Hydroxylizaric acid,Verantin

Target: MAO, Antibacterial, Antibiotic, Antifungal

Cat.No: T0687

Synonym: 辛伐他汀,MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: TN1016

Target: NF-κB, Lipoxygenase, DNA/RNA Synthesis, Parasite

Cat.No: T6856

Synonym: 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110

Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Cat.No: TN1120

Target: MAO, Monoamine Oxidase

D-Ribonolactone

Cat.No: T10941

Synonym: D-(+)-核糖酸-1,4-内酯,D-核糖内酯

Target: Endogenous Metabolite, Antibacterial

4,5-Dimethoxycanthin-6-one

Cat.No: TN3013

Synonym: Methylnigakinone

Target: P450, Antibacterial, PDE

2-Hydroxycaprylic acid

Cat.No: T7481

Synonym: 2-hydroxyoctanoic acid,2-羟基辛酸

Target: Others

Cat.No: T4000

Synonym: Equol,(±)-雌马酚,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Cat.No: TN1736

Synonym: 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷

Target: Adenosine deaminase

Adenine monohydrochloride hemihydrate

Cat.No: T5081

Synonym: 腺嘌呤盐酸盐,Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate

Target: Endogenous Metabolite, Adenosine Receptor

N-Nornuciferine hydrochloride(4846-19-9 free base)

Cat.No: TQ0296L

Synonym: N-Nornuciferine hydrochloride

Target: P450

Cat.No: T6430

Synonym: 25-羟基维生素 D3,U 32070E,25-hydroxy Vitamin D3,RO 8-8892,骨化二醇

Target: Endogenous Metabolite

Cat.No: TN1849

Target: GPR, Bombesin Receptor

Cat.No: TN3748

Synonym: D-天冬酰胺,H-D-Asn-OH

Target: Others, Endogenous Metabolite

7-Chlorokynurenic acid

Cat.No: T10191L

Synonym: 7-chloro-4-hydroxy-2-carboxyquinoline,7-氯犬尿酸,7-CKA

Target: GluR, NMDAR

Cat.No: TN1982

Target: Others

Aminomalonic acid

Cat.No: T5244

Synonym: 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate

Target: Others, Endogenous Metabolite

Cat.No: T2926

Target: P450, Virus Protease, Autophagy

Cat.No: TN1650

Synonym: 软木三萜酮,无羁萜

Target: P450, NOS, Caspase, Prostaglandin Receptor

Gentiopicroside

Cat.No: T2770

Synonym: Gentiopicrin,龙胆苦甙,龙胆苦苷

Target: P450, HCV Protease

Salvianolic Acid C

Cat.No: T3149

Synonym: 丹酚酸C,丹酚酸 C

Target: Others, P450

Allopurinol riboside

Cat.No: T13539

Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite

Cat.No: TN1800

Target: Others

Cat.No: T2144

Synonym: 他克莫司,Fujimycin,FK506,FR900506

Target: Phosphatase, Others, Antibacterial, Antibiotic, mTOR, Autophagy

Tricarballylic acid

Cat.No: T5564

Synonym: β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸

Target: aconitase, Mitochondrial Metabolism

Cat.No: T5568

Synonym: 3-碘-L-酪氨酸,3-Iodo-L-tyrosine

Target: Endogenous Metabolite

Cat.No: T6323

Synonym: MCH 32,寡霉素A

Target: ATPase, Antibiotic, Antifungal

Cat.No: T14853

Synonym: FCE-21336,卡麦角林

Target: Dopamine Receptor, 5-HT Receptor, Autophagy

Cat.No: T7671

Synonym: 麦司明,麦斯明

Target: Others, AChR

Cat.No: T4024

Synonym: 2-Azacarbazole,2,9-Diazafluorene,β-Carboline,去甲哈尔满

Target: DNA, Endogenous Metabolite, Monoamine Oxidase

Cat.No: T5S0669

Synonym: 5-Geranoxypsoralen,Bergamotine,Bergaptin,佛手柑素

Target: P450

alpha-Naphthoflavone

Cat.No: T2O2744

Synonym: 苯并黄素；α-萘黄酮；7,8-苯并黄酮,7,8-benzoflavone,α-萘黄酮

Target: Aromatase

Tetrahydromagnolol

Cat.No: TN2268

Target: Cannabinoid Receptor, GPR, GABA Receptor

N-Methylcytisine

Cat.No: T5S0994

Synonym: N-甲基野靛碱,Caulophylline

Target: Others, AChR

Cat.No: T1310

Synonym: Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶

Target: Thyroid hormone receptor(THR), NO Synthase

Coptisine sulfate

Cat.No: T4S0051

Target: Indoleamine 2,3-Dioxygenase (IDO)

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E,tumor necrosis factor receptor superfamily, member 8...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-03105	Ki67/MKI67 Protein, Human, Recombinant (GST) MIB-1,PPP1R105,marker of proliferation Ki-67,MIB-,<...	Human	E. coli
	MKI67 contains 1 FHA domain and plays a key role in cell proliferation. During interphase, the MKI67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. MKI67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells. MKI67 is an excellent marker to determine the growth fraction of a given cell population. The fraction of MKI67-positive tu...
TMPY-05443	CD30/TNFRSF8 Protein, Mouse, Recombinant (His) Ki-1,Ki,D1S166E,Cd30,tumor necrosis factor...	Mouse	HEK293 Cells
	CD30/TNFRSF8 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q60846.
TMPY-05737	CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc) Cd30,Ki,tumor necrosis factor receptor superfamily,...	Mouse	HEK293 Cells
	CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.92 kDa and the accession number is Q60846.
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His) KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...	Human	E. coli
	KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His) NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2B,K-RAS,Kirsten...	Human	E. coli
	KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His) KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene ho...	Human	E. coli
	KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His) Kirsten rat sarcoma viral oncogene homolog,KRAS2,	Human	E. coli
	KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPH-01917	MKI67 Protein, Human, Recombinant (E. coli, His) MKI67,Antigen identified by monoclonal antibody	Human	E. coli
	MKI67 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-01918	MKI67 Protein, Human, Recombinant (His) MKI67,Proliferation marker protein Ki-67,A...	Human	P. pastoris (Yeast)
	MKI67 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPJ-01436	MKI67 Protein, Human, Recombinant (GST) Ki-67,Antigen Ki67,MKI67,KI	Human	E. coli
	MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition...
TMPH-01418	KRAS Protein, Human, Recombinant (His) c-Ki-ras,KRAS,K-Ras 2,GTPase KRas,c-K-ras,Ki	Human	E. coli
	KRAS Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-06282	CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated tumor necrosis factor receptor superfamily, member 8,Ki<...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 67.02 kDa and the accession number is P28908-1.
TMPY-05471	CD30/TNFRSF8 Protein, Human, Recombinant (hFc) Ki-1,tumor necrosis factor receptor superfamily, me...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.2 kDa and the accession number is P28908-1.
TMPY-03614	PSME3 Protein, Human, Recombinant (His) PA28G,PA28-gamma,HEL-S-283,REG-GAMMA,proteasome (prosome, ma...	Human	E. coli
	PSME3, also known as PA28-gamma, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase su...
TMPY-06430	CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated Ki-1,CD30,D1S166E,tumor necrosis factor receptor su...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.74 kDa and the accession number is P28908-1.
TMPY-05118	CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated D1S166E,Ki-1,tumor necrosis factor receptor superfa...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.9 kDa and the accession number is P28908-1.
TMPJ-00510	KRAS Protein, Human, Recombinant (G12C, His) RASK2,c-K-ras,CFC2,KRAS2,Ki-Ras	Human	E. coli
	KRAS Protein, Human, Recombinant (G12C, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26 KDa and the accession number is AAH13572.1.
TMPJ-00511	KRAS Protein, Human, Recombinant (G12V, His) KRAS2,RASK2,c-K-ras,Ki-Ras,CFC2	Human	E. coli
	KRAS Protein, Human, Recombinant (G12V, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25-30 KDa and the accession number is AAH13572.1.
TMPK-00078	CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled TNFSF7, Ki-24 antigen,CD70,TNFSF7G,CD70 molecule,CD...	Human	HEK293 Cells
	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51.8 kDa and ...
TMPK-00080	CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated CD27-L,CD70 molecule,TNFSF7G,CD70,CD27LG,CD27 Ligand,TNFSF7,...	Human	HEK293 Cells
	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecula...
TMPK-00079	CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His) TNFSF7,CD27 Ligand, Ki-24 antigen,CD70 molecule,CD2...	Human	HEK293 Cells
	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51.8 kDa and the accession ...
TMPK-00666	CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) CD70 molecule,TNFSF7,CD70,TNFSF7G,CD27-L,CD27LG,CD27 Ligand,...	Cynomolgus	HEK293 Cells
	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.4 kDa and the accession nu...
TMPJ-00342	CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His) Lymphocyte activation antigen CD30,TNFRSF8,Tumor necrosis fa...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 60-95 KDa and the accession number is P28908.
TMPJ-00341	CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) TNFRSF8,Ki-1 antigen,CD30,CD30L receptor,Tumor necr...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
TMPJ-00340	CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated Lymphocyte activation antigen CD30,TNFRSF8,CD30,Ki-...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is P28908.
TMPJ-00240	CAMK1 Protein, Human, Recombinant (His) CaM Kinase I Alpha,CaMKI-α,CaM Ki...	Human	HEK293 Cells
	Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed. CAMK1 is phosphorylated by CaMKK1 and CaMKK2 on Thr-177. CAMK1 regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization, and neurite outgrowth. CAMK1 plays a role in K+ and ANG2-mediated regulation of the aldo...
TMPJ-00343	CD30/TNFRSF8 Protein, Human, Recombinant (mFc) TNFRSF8,Tumor necrosis factor receptor superfamily member 8,...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
TMPK-01462	HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated K-RAS4A,K-RAS2A,CFC2,KRAS1,K-RAS4B,C-K-RAS,KRAS,K-RAS2B,K-Ra...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS2B,K-Ras 2,C-K-RAS,RASK2,K-...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01405	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi) KI-RAS,RASK2,K-Ras 2,MHC,KRAS,KRAS1,NS3,K-RAS2A,K-R...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01511	HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated GTPase Kras,K-RAS4A,KI-RAS,K-RAS4B,C-K-RAS,K-Ras 2,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01460	HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,K-RAS2A,KI-RAS,K-RAS4B,RALD,NS3,GTPase Kras,K-R...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01428	HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi) CFC2,K-RAS4B,K-Ras 2,C-K-RAS,RASK2,NS3,RALD,KI-RAS,...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01443	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), FITC-Labeled KRAS1,C-K-RAS,K-RAS4B,RALD,K-Ras 2,K-RAS2A,K-RAS2B,KRAS2,NS3...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01440	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled RASK2,KI-RAS,C-K-RAS,KRAS,MHC,NS,K-RAS4A,K-RAS2B,CF...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01432	HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Tetramer Protein, Human, MHC (His & Avi) RASK2,K-RAS4A,K-RAS4B,KRAS2,CFC2,MHC,KRAS,KI-RAS,K-...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01512	HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi) K-Ras 2,NS,NS3,K-RAS2B,CFC2,MHC,KRAS1,GTPase Kras,K-RAS4A,KR...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01435	HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled KRAS2,NS3,RASK2,KI-RAS,RALD,K-RAS2B,K-RAS4B,GTPase ...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01430	HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi) K-RAS2A,RALD,NS3,K-Ras 2,KI-RAS,NS,MHC,K-RAS2B,K-RA...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01465	HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS2A,CFC2,KRAS,GTPase Kras,K-RAS2B,K-Ras 2,KI	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B,KI-RAS,K...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01402	HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated KRAS1,NS,CFC2,K-RAS4B,RASK2,K-Ras 2,KI-RAS,GTPase K...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01528	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi) KRAS1,MHC,K-RAS2B,K-RAS4B,NS,GTPase Kras,K-Ras 2,KI...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01438	HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled RASK2,KRAS2,KRAS1,MHC,C-K-RAS,KI-RAS,K-RAS4B,RALD,K...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01507	HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi) K-RAS2A,K-RAS4B,KI-RAS,RALD,C-K-RAS,RASK2,NS,MHC,NS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01404	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated NS,KRAS,KRAS1,KRAS2,MHC,RALD,K-RAS4A,K-RAS2A,K-RAS4B,K-RAS2B...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01434	HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi) RASK2,CFC2,GTPase Kras,KRAS,K-RAS2B,MHC,K-RAS2A,K-RAS4A,KRAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01525	HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated CFC2,RALD,K-Ras 2,MHC,C-K-RAS,NS3,GTPase Kras,KRAS2,K-RAS4B,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01403	HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi) K-Ras 2,KI-RAS,CFC2,KRAS1,GTPase Kras,KRAS,K-RAS4B,...	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
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重组蛋白

CD30/TNFRSF8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01827

Species: Human

Expression System: HEK293 Cells

Ki67/MKI67 Protein, Human, Recombinant (GST)

Cat.No: TMPY-03105

Species: Human

Expression System: E. coli

CD30/TNFRSF8 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05443

Species: Mouse

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-05737

Species: Mouse

Expression System: HEK293 Cells

KRAS Protein,Human, Recombinant (Q61H, His)

Cat.No: TMPY-01888

Species: Human

Expression System: E. coli

KRAS Protein,Human,Recombinant(G12C & Q61H, His)

Cat.No: TMPY-04116

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (G12D, His)

Cat.No: TMPY-06056

Species: Human

Expression System: E. coli

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Cat.No: TMPY-04113

Species: Human

Expression System: E. coli

MKI67 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01917

Species: Human

Expression System: E. coli

MKI67 Protein, Human, Recombinant (His)

Cat.No: TMPH-01918

Species: Human

Expression System: P. pastoris (Yeast)

MKI67 Protein, Human, Recombinant (GST)

Cat.No: TMPJ-01436

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (His)

Cat.No: TMPH-01418

Species: Human

Expression System: E. coli

CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06282

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05471

Species: Human

Expression System: HEK293 Cells

PSME3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03614

Species: Human

Expression System: E. coli

CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06430

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05118

Species: Human

Expression System: HEK293 Cells

KRAS Protein, Human, Recombinant (G12C, His)

Cat.No: TMPJ-00510

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (G12V, His)

Cat.No: TMPJ-00511

Species: Human

Expression System: E. coli

CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled

Cat.No: TMPK-00078

Species: Human

Expression System: HEK293 Cells

CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00080

Species: Human

Expression System: HEK293 Cells

CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)

Cat.No: TMPK-00079

Species: Human

Expression System: HEK293 Cells

CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00666

Species: Cynomolgus

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)

Cat.No: TMPJ-00342

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)

Cat.No: TMPJ-00341

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated

Cat.No: TMPJ-00340

Species: Human

Expression System: HEK293 Cells

CAMK1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00240

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-00343

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01462

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01450

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01405

Species: Human

Expression System: E. coli

HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01511

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01460

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01428

Species: Human

Expression System: E. coli

HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), FITC-Labeled

Cat.No: TMPK-01443

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01440

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01432

Species: Human

Expression System: HEK293 Cells

HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01512

Species: Human

Expression System: HEK293 Cells

HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01435

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01430

Species: Human

Expression System: E. coli

HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01465

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01456

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

Cat.No: TMPK-01402

Species: Human

Expression System: E. coli

HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01528

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01438

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01507

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

Cat.No: TMPK-01404

Species: Human

Expression System: E. coli

HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01434

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01525

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01403

Species: Human

Expression System: E. coli

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Cat. No.	Product Name	Target	Signaling Pathways
T10681	Cariprazine D6 RGH-188 D6	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
T12736	Rivaroxaban-d4 BAY 59-7939 D4	Factor Xa	Metabolism
	Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM; Ki:0.4 nM).
T11270	Febuxostat D9 非布司他D9	Others	Others
	Febuxostat D9 is deuterium labeled Febuxostat, which is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.
T10113	3-Hydroxy agomelatine D3	5-HT Receptor	GPCR/G Protein; Neuroscience
	3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).
T10368	Aripiprazole (D8) OPC-14597 D8	Others	Others
	Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).
T10950	Dabigatran D4 hydrochloride BIBR-953 D4 hydrochloride	Others	Others
	Dabigatran D4 hydrochloride is deuterium-labeled dabigatran, which is a reversible and selective direct thrombin inhibitor (DTI) with a Ki value of 4.5 nM.
T10842	Clomipramine D3 氯米帕明 D3	Others	Others
	Clomipramine D3 is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).
T10842L	Clomipramine D3 hydrochloride	Others	Others
	Clomipramine D3 hydrochloride is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).
TMIH-0417	Oxprenolol hydrochloride-d7
	Oxprenolol hydrochloride-d7 是 Oxprenolol hydrochloride 的氘代化合物。Oxprenolol hydrochloride 的 CAS 号为 6452-73-9。Oxprenolol hydrochloride 是一种有效的、具有口服活性的β-肾上腺素受体拮抗剂，Ki为 7.10 nM。
T10349	Apixaban 13C,d3 Apixaban 13CD3,BMS-562247-01 13CD3	Others	Others
	Apixaban 13CD3 (BMS-562247-01 13CD3) is a deuterium-labeled Apixaban. Apixaban is a reversible inhibitor of Factor Xa (Ki: 0.08 nM and 0.17 nM in human and rabbit).
T10610	Brexpiprazole-d8 OPC-34712 D8	Others	Others
	Brexpiprazole D8 (OPC-34712 D8) is a deuterium-labeled Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Ki: 0.12 nM and 0.3 nM).
T73711	Atomoxetine-d3 hydrochloride
	Atomoxetine-d3 hydrochloride 是氘代标记的Atomoxetine hydrochloride。Atomoxetine hydrochloride 是去甲肾上腺素重吸收抑制剂，与人NET，SERT 和DAT 的放射性配体结合的 Ki 分别为5，77和1451 nM。
T11295	Flibanserin-d4 BIMT-17BS D4,BIMT-17 D4,Flibanserin D4	Others	Others
	Flibanserin, a compound identified as BIMT-17, acts as a complete agonist at the serotonin 5-HT1A receptor, with a binding affinity (Ki) of 1 nM, while functioning as an antagonist at the 5-HT2A receptor with a 49 nM affinity. Flibanserin D4 represents a deuterium-labeled version of Flibanserin.
T73715	Risperidone-d4
	Risperidone-d4是 Risperidone 的氘代物。Risperidone 是5-HT2受体的阻断剂，P-糖蛋白(P-Glycoprotein)的抑制剂和dopamine D2受体的拮抗剂，其对 5-HT2A 和 dopamine D2受体的Ki 值分别为 4.8，5.9 nM。
T11113	Duloxetine D3 hydrochloride (S)-Duloxetine D3 hydrochloride,LY248686 D3 hydrochloride	Others	Others
	Duloxetine D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).Duloxetine D3 hydrochloride ((S)-Duloxetine D3 hydrochloride) i
TMIH-0461	Prucalopride-13C-d3
	Prucalopride-13C-d3 是 Prucalopride 的 13C 和氘代化合物。Prucalopride 的 CAS 号为 179474-81-8。Prucalopride 是一种选择性、高亲和力的 5-HT4A/4B 受体激动剂，Ki为2.5和 8 nM。它对 5-HT4A/4B 受体的选择性是其他 5-HT 受体亚型的 290 倍以上。
TMIH-0110	Benzbromarone-d5
	Benzbromarone-d5 是 Benzbromarone 的氘代化合物。Benzbromarone 的 CAS 号为 3562-84-3。Benzbromarone 是一种高效的，耐受性良好的非竞争性黄嘌呤氧化酶抑制剂，用作排尿酸剂，研究痛风。
TMIJ-0040	17alpha-Estradiol-2,4-d2
	17alpha-Estradiol-2,4-d2 是 17alpha-Estradiol 的氘代化合物。17alpha-Estradiol 的 CAS 号为 57-91-0。17α-Estradiol 是一种雌性激素，可抑制5α-reductase，在雄原性脱发的研究中有潜力。
T71302	Norfluoxetine-d5 HCl
	Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa...
TMIH-0198	DM-3411-d8 Brexpiprazole Metabolite
	DM-3411-d8 是 DM-3411 的氘代化合物。DM-3411 的 CAS 号为 913611-97-9。Brexpiprazole是人5-HT1A和多巴胺受体的部分激动剂，Ki分别为0.12 和 0.3 nM。它也是5-HT2A受体的拮抗剂，Ki为 0.47 nM，可作为非典型抗精神病药。
T70394	Deucravacitinib HCl
	Deucravacitinib HCl is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease. MS-986165 potently binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM), and is highly selective against a panel of 265 kinases and pseudokinases. The compound potently inhibited IL-23-, IL-12-, and Type I interferon-driven cellular signaling and transcriptional resp...
T69598	Isoproterenol-d7 HCl
	Isoproterenol-d7 is intended for use as an internal standard for the quantification of isoproterenol by GC- or LC-MS. Isoproterenol is an agonist of β1- and β2-adrenergic receptors (β1- and β2-ARs; Kis = 224 and 458 nM, respectively). It is selective for β1- and β2-ARs over β3-ARs (Ki = 1,570 nM). Isoproterenol inhibits contractions in isolated field-stimulated rat vas deferens (EC50 = 45.6 nM). In vivo, isoproterenol (0.33 mg/kg) decreases blood pressure and increases water intake in nephrectom...
TMIH-0485	Ramelteon-d3
	Ramelteon-d3 是 Ramelteon 的氘代化合物。Ramelteon 的 CAS 号为 196597-26-9。Ramelteon 是强效高选择性和可口服的MT1/MT2激动剂，Ki值分别为 14 和 112 pM，有用于失眠症的研究潜力。
TMIH-0486	Ramelteon-d5
	Ramelteon-d5 是 Ramelteon 的氘代化合物。Ramelteon 的 CAS 号为 196597-26-9。Ramelteon 是强效高选择性和可口服的MT1/MT2激动剂，Ki值分别为 14 和 112 pM，有用于失眠症的研究潜力。
T73820	Bosentan-d4
	Bosentan-d4 是 Bosentan 的氘代物。Bosentan 是一种有效的endothelin-1 (ET)拮抗剂，在人的 SMC 细胞中，作用于ETA 和ETB 受体，Ki 值分别为 4.7 nM 和 95 nM。
TMIJ-0004	Perphenazine-d4
	Perphenazine-d4 是 Perphenazine 的氘代化合物。Perphenazine 的 CAS 号为 58-39-9。Perphenazine 是吩噻嗪衍生物和多巴胺拮抗剂，具有止吐和抗精神病特性。它能够抑制5-HT2A受体，α1A肾上腺素能受体，多巴胺D2、D3、D2L受体，以及组胺H1受体，对应的Ki值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
TMIH-0444	Pitofenone-d4
	Pitofenone-d4 是 Pitofenone 的氘代化合物。Pitofenone 的 CAS 号为 1248-42-6。Pitofenone hydrochloride 是一种能够抑制乙酰胆碱酯酶活性的解痉化合物，对于来自牛红细胞和电鳗的乙酰胆碱酯酶的Ki分别为 36 和 45 μM。
T35591	Guanfacine-13C,15N3 Guanfacine-13C,15N3
	Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin...
TMIH-0605	Vortioxetine-d8 2HBr
	Vortioxetine-d8 2HBr 是 Vortioxetine 2HBr 的氘代化合物。Vortioxetine 2HBr 的 CAS 号为 508233-74-7。Vortioxetine 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂，Ki值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药，用于治疗重度抑郁症。
TMIH-0205	Duloxetine-d3 HCl
	Duloxetine-d3 HCl 是 Duloxetine HCl 的氘代化合物。Duloxetine HCl 的 CAS 号为 136434-34-9。Duloxetine hydrochloride 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂 (SNRI)，Ki=4.6 nM，可用于广泛性焦虑症的研究。
TMIH-0173	Dabigatran-d4 HCl
	Dabigatran-d4 HCl 是 Dabigatran HCl 的氘代化合物。Dabigatran HCl 的 CAS 号为 211914-51-1。Dabigatran 是一种口服抗凝剂，是一种可逆的，竞争性的直接凝血酶 (thrombin) 抑制剂，Ki=4.5 nM。它也抑制凝血酶诱导的血小板聚集 (IC50=10 nM)。
TMIJ-0002	Dabigatran-13C6
	Dabigatran-13C6 是 Dabigatran 的 13C 的标记化合物。Dabigatran 的 CAS 号为 211914-51-1。Dabigatran 是一种口服抗凝剂，是一种可逆的，竞争性的直接凝血酶 (thrombin) 抑制剂，Ki=4.5 nM。它也抑制凝血酶诱导的血小板聚集 (IC50=10 nM)。
TMIJ-0003	Dabigatran-13C-d3
	Dabigatran-13C-d3 是 Dabigatran 的 13C 和氘代化合物。Dabigatran 的 CAS 号为 211914-51-1。Dabigatran 是一种口服抗凝剂，是一种可逆的，竞争性的直接凝血酶 (thrombin) 抑制剂，Ki=4.5 nM。它也抑制凝血酶诱导的血小板聚集 (IC50=10 nM)。
TMIH-0096	Apigenin-d6
	Apigenin-d6 是 Apigenin 的氘代化合物。Apigenin 的 CAS 号为 520-36-5。Apigenin 是从韩信草中提取的一种天然产物，是一种竞争性CYP2C9抑制剂，Ki为 2 μM。它被用作镇静剂、温和的镇痛剂和安眠药。
TMID-0053	Amisulpride-d5
	Amisulpride-d5 是 Amisulpride 的氘代化合物。Amisulpride 的 CAS 号为 71675-85-9。Amisulpride 是多巴胺D2/D3受体拮抗剂，对于人多巴胺D2和D3的Ki分别为 2.8 和 3.2 nM。
TMIH-0095	Apigenin-d4
	Apigenin-d4 是 Apigenin 的氘代化合物。Apigenin 的 CAS 号为 520-36-5。Apigenin 是从韩信草中提取的一种天然产物，是一种竞争性CYP2C9抑制剂，Ki为 2 μM。它被用作镇静剂、温和的镇痛剂和安眠药。
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...
T12476	Pimozide-d4 Pimozide D4,R6238 D4	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Pimozide D4 is a deuterium labeled Pimozide.
T10611	Brexpiprazole S-oxide D8 DM-3411 D8	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Kis: 0.12 nM and 0.3 nM).

同位素

Cat.No: T10681

Synonym: RGH-188 D6

Target: Dopamine Receptor

Cat.No: T12736

Synonym: BAY 59-7939 D4

Target: Factor Xa

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Synonym: 非布司他D9

Target: Others

3-Hydroxy agomelatine D3

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Aripiprazole (D8)

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Synonym: OPC-14597 D8

Target: Others

Dabigatran D4 hydrochloride

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Synonym: BIBR-953 D4 hydrochloride

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Clomipramine D3

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Clomipramine D3 hydrochloride

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Target: Others

Oxprenolol hydrochloride-d7

Cat.No: TMIH-0417

Apixaban 13C,d3

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Synonym: Apixaban 13CD3,BMS-562247-01 13CD3

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Brexpiprazole-d8

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Synonym: OPC-34712 D8

Target: Others

Atomoxetine-d3 hydrochloride

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Prucalopride-13C-d3

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Benzbromarone-d5

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17alpha-Estradiol-2,4-d2

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Norfluoxetine-d5 HCl

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Synonym: Brexpiprazole Metabolite

Deucravacitinib HCl

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Isoproterenol-d7 HCl

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Cat.No: TMIH-0485

Cat.No: TMIH-0486

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Perphenazine-d4

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Guanfacine-13C,15N3

Cat.No: T35591

Synonym: Guanfacine-13C,15N3

Vortioxetine-d8 2HBr

Cat.No: TMIH-0605

Duloxetine-d3 HCl

Cat.No: TMIH-0205

Dabigatran-d4 HCl

Cat.No: TMIH-0173

Dabigatran-13C6

Cat.No: TMIJ-0002

Dabigatran-13C-d3

Cat.No: TMIJ-0003

Cat.No: TMIH-0096

Cat.No: TMID-0053

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Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

Cat.No: T12476

Synonym: Pimozide D4,R6238 D4

Target: Dopamine Receptor

Brexpiprazole S-oxide D8

Cat.No: T10611

Synonym: DM-3411 D8

Target: Dopamine Receptor, 5-HT Receptor

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