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Targets Recommended: Adenosine Receptor

2505

抑制剂 & 化合物

141

天然产物

81

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9238 KI-7

Adenosine Receptor GPCR/G Protein; Neuroscience
KI-7 是一种A2B 腺苷受体阳性变构调节剂。它增强选择性 A2B 腺苷受体激动剂 BAY 60-6583 和腺苷诱导的 cAMP 积累,EC50分别为 2390 nM 和 2550 nM。它也增强非选择性 A2B 腺苷受体激动剂 NECA 诱导的 cAMP 积累,EC50为 445.8 nM。
T11758L KI696

Nrf2 Immunology/Inflammation
KI696 是一种高亲和力探针,可有效抑制 Keap1 和 NRF2 的相互作用。
T2446 KI8751

EGFR; VEGFR; FGFR; PDGFR; c-Kit Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Ki8751 是一种有效的 VEGFR2 抑制剂,其 IC50=0.9 nM。
T11758 KI696 isomer

Nrf2 Immunology/Inflammation
KI696 isomer 是 KI696 的异构体,是一种亲和力较低的探针,可用于研究免疫和代谢疾病。
T6108 Ki16425

Debio 0719

LPA Receptor; LPL Receptor GPCR/G Protein
Ki16425 (Debio 0719) 是一种竞争性、有效和可逆的 LPA1、LPA2 和 LPA3 拮抗剂,Ki 分别为 0.34、6.5 和 0.93 μM。它可抑制LPA 诱导的 HEK293A 细胞中 YAP/TAZ 的去磷酸化,降低LPA 诱导的 p42/p44 MAPK 激活。
T6347 Ki16198

LPA Receptor; LPL Receptor GPCR/G Protein
Ki16198 是一种可口服的 LPA 受体拮抗剂,是 Ki16425 的甲酯衍生物。它抑制 LPA1 和 LPA3 诱导的肌醇磷酸的Ki 值分别为 0.34 和 0.93 μM,可用于胰腺癌发生和转移的研究。
T4315 Ki20227

N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲

c-Fms; VEGFR; CSF-1R; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Ki20227 是一种高效的、口服具有活性的、选择性的CSF1R(c-Fms 酪氨酸激酶)抑制剂,对 CSF1R,VEGFR2,c-Kit 和PDGFRβ的IC50分别为 2 nM,12 nM,451 nM 和 217 nM。它可以阻止破骨细胞分化和溶骨性破坏。
T68313 KI-328

KI-328 is a novel KIT inhibitor. KI-328 shows selective potency against KIT kinase for the in vitro kinase assay, and inhibits the growth of wild-type (Wt)- and mutant-KIT-expressing cells, while it has little potency against D816V-KIT.
T69162 Ki23057

Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treating drug-resistant gastric cancer cells, especially when used in combination with SN38, PTX, or VP16. The apoptosis process might be the main mechanism underlying the synergistic effect of these combinations. The ERCC1 and p53 genes may play an integral role in the synergism betwee...
T74402 FAP-PI3KI1

FAP-PI3KI1 是一种成纤维细胞活化蛋白 (FAP) 靶向 PI3K 抑制剂,可选择性靶向表达 FAP 的人特发性肺纤维化 (IPF)细胞并有效抑制胶原蛋白合成,减少胶原蛋白沉积。
T4607 CAY 10465

CAY10465,CAY10465 Exclusive

AhR; Aryl Hydrocarbon Receptor Immunology/Inflammation; Metabolism
CAY 10465 是一种选择性和高亲和力的芳香烃受体(AhR)激动剂,Ki 值为 0.2 nM。
T10261 AGN 196996

Others; Retinoid Receptor; Autophagy Autophagy; Metabolism; Others
AGN 196996是一种高效且具有选择性的RARα抑制剂(Ki:2 nM)。AGN 196996对RARβ和RARγ的亲和性极低,Ki 分别为1087 nM 和8523 nM。
T27800 LAS38096

LAS 38096,LAS-38096

Adenosine Receptor GPCR/G Protein; Neuroscience
LAS38096 是一种A2B 腺苷受体拮抗剂(Ki :17 nM),具有强效性、选择性和高效性 。
T5587 CGP71683 hydrochloride

CGP71683A,盐酸CGP71683

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
CGP71683 hydrochloride (CGP71683A) 是竞争性的神经肽受体拮抗剂,Ki 值为 1.3 nM。
TQ0084 lumateperone Tosylate

ITI-007,Lumateperone甲苯磺酸盐

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
lumateperone Tosylate (ITI-007) 是5-HT 2A 受体拮抗剂,Ki 为 0.54 nM,突触前 D2受体的部分激动剂和突触后 D2受体的拮抗剂,Ki 为 32 nM。
T15712 Laropiprant

MK-0524

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Laropiprant (MK-0524) 是 DP receptor 的选择性拮抗剂,Ki 为 0.57 nM,对 TP 受体的 Ki 为 2.95 nM。
T2373 Vipadenant

CEB-4520,BIIB-014

Adenosine Receptor GPCR/G Protein; Neuroscience
Vipadenant (CEB-4520) 是一种腺苷受体拮抗剂,抑制 A2A 和 A1 活性的 Ki 值分别为 1.3 和 68 nM。
T23782 Benzolamide

CL-11366,W 1803,CL 11366,CL11366,苯唑拉胺,W-1803

Carbonic Anhydrase Metabolism
Benzolamide (CL 11366) 是碳酸酐酶 (CA) 抑制剂,抑制hCA I(Ki:15 nM)、hCA II(Ki:9 nM)、EcoCAγ(Ki:94 nM)、VchCAγ(Ki:78 nM)、CAS3(Ki:54 nM)。它可用于研究青光眼和癫痫。
T15682 L-371,257

Oxytocin Receptor; Vasopressin Receptor Endocrinology/Hormones; GPCR/G Protein
L-371,257 是催产素受体的竞争性拮抗剂,pA2 为 8.4,Ki 为 19 nM。 L-371,257 对加压素受体 1a 的 Ki 值为 3.7 nM。
T41247 Thioperamide maleate

MR-12842 maleate,硫丙咪胺马来酸

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Thioperamide maleate (MR-12842 maleate) 是一种有效且选择性的 H3 受体拮抗剂 (Ki = 4.3 nM),可抑制 [3H]histamine 的合成 (Ki = 31 nM)。
T15595L IRL-1620 acetate

IRL-1620 acetate(142569-99-1 free base)

Endothelin Receptor GPCR/G Protein
IRL-1620 acetate 是一种有效的特异性内啡肽 B 受体 (ETB) 激动剂,Ki 为 16 pM,相比于ETA,其Ki 为 19 μM。
T37696 NOS1-IN-1

nNOS Inhibitor I

NOS Immunology/Inflammation
NOS1-IN-1(nNOS Inhibitor I) 是一种强效、选择性和细胞渗透性 nNOS 抑制剂(Ki:120 nM)。NOS1-IN-1 对 eNOS 的 Ki 值为 39 μM,对 iNOS 的 Ki 值为 325 μM。
T39284 EST73502 HCl

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
EST73502 是 μ-阿片受体激动剂 (Ki = 64 nM) 激动剂和 σ1 受体拮抗剂 (Ki = 118 nM)。 EST73502 显示出镇痛活性。
T15270 Fananserin

RP 62203,法南色林

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
Fananserin 是一种有效的、特异性的、口服活性的 5-HT2 拮抗剂(大鼠 5-HT2A 的 Ki = 0.37 nM)。 Fananserin 是人 D4 受体的拮抗剂 (Ki = 2.93 nM)。
T1749 AL 082D06

D-06,AL082D06

Glucocorticoid Receptor Endocrinology/Hormones
AL 082D06 (D-06) 是非甾体类糖皮质激素受体 (GR) 选择性拮抗剂(Ki:210 nM)。
T14069 A-3 hydrochloride

CaMK; Casein Kinase; PKA; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Neuroscience; Stem Cells; Tyrosine Kinase/Adaptors
A-3 hydrochloride 是一种细胞可渗透的、可逆的、ATP 竞争性非选择性拮抗剂。它抑制 PKA 、酪蛋白激酶 II 和肌球蛋白轻链激酶,Ki 值分别为4.3 µM、5.1 µM 和7.4 µM。它还抑制 PKC 和酪蛋白激酶 I 的活性,Ki 分别为 47 µM 和 80 µM。
T7343 PF-04979064

PI3K; mTOR PI3K/Akt/mTOR signaling
PF-04979064 是一种选择性 PI3K/mTOR 双重激酶抑制剂,能够抑制 PI3Kα (Ki=0.13 nM) 和 mTOR (Ki=1.42 nM)。
T1865 S1RA

E-52862,4-(2-((5-甲基-1-(2-萘基)-1H-吡唑-3-基)氧基)乙基)吗啉

Sigma receptor GPCR/G Protein
S1RA (E-52862) 是一种有效且特异性的 sigma-1受体拮抗剂,Ki 为17nM,对 σ2R 具有良好的选择性,Ki 值大于 1000 nM。
T0713 Drofenine hydrochloride

盐酸六氢芬宁,Hexahydroadiphenine hydrochloride

AChE Neuroscience
Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) 是竞争性胆碱酯酶抑制剂,ki=3 uM。
T28531 Facinicline hydrochloride

RG3487

5-HT Receptor; AChR GPCR/G Protein; Neuroscience
Facinicline hydrochloride (RG3487) 是一种口服有效的烟碱α7 receptor 部分激动剂,对人 nAChR 的 Ki 值为 6 nM。它可改善啮齿类动物的认知和感觉运动门控。它与5-HT3受体结合的 Ki 为 1.2 nM。
T2420 PHT-427

PHT 427,CS-0223

Apoptosis; Akt; PDK Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
PHT-427 (CS-0223) 是一种 Akt 和 PDPK1双重抑制剂,与 Akt 和 PDPK1 中的 PH 结构域有亲和性,Ki 分别为 2.7 μM 和 5.2 μM。
T8419 XP-59

SARS-CoV Microbiology/Virology
XP-59 是一种 SARS-CoV Mpro 抑制剂,其 Ki 值为 0.1 nM。
T14151 AKR1C1-IN-1

NADPH Metabolism
AKR1C1-IN-1 是高选择性 AKR1C1抑制剂(Ki:4 nM)。
T2009 SB-3CT

MMP Proteases/Proteasome
SB-3CT 是一种可透过血脑屏障的、竞争性的金属蛋白酶MMP-2和MMP-9抑制剂,Ki 分别为 13.9 nM、600 nM。他对明胶酶具有高选择性。它具有神经保护和抗癌作用。
T15811 LY2955303

Others; Retinoid Receptor Metabolism; Others
LY2955303 是一种有效的特异性视黄酸受体 γ 拮抗剂(RARγ,Ki = 1.09 nM)。
T10691 CAY10595

GPR Endocrinology/Hormones; GPCR/G Protein
CAY10595 是 CRTh2 (DP2) 受体的拮抗剂,Ki 为 10 nM。
T35347 Et-29

NRD167

Sirtuin Chromatin/Epigenetic; DNA Damage/DNA Repair
Et-29 是一种特异性的 SIRT5 抑制剂,Ki 为 40 nM。
T2688 LY310762

LY310762 HCl

5-HT Receptor GPCR/G Protein; Neuroscience
LY310762 是 5-HT1D 受体拮抗剂,Ki 为 249 nM。
T2017 U-104

NSC-213841,MST-104

Carbonic Anhydrase Metabolism
U-104 (NSC-213841) 是 CA IX 和 CA XII 碳酸酐酶 (CA) 抑制剂,其 Ki 分别为 45.1 nM 和 4.5 nM。小鼠模型中,它能够表现出明显的抑制肿瘤生长的作用。
T12306 OMDM-5

Cannabinoid Receptor; Endogenous Metabolite; TRP/TRPV Channel GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
OMDM-5 是有效的、选择性的anandamide 细胞摄取抑制剂,Ki 为 4.8 μM。它是VR1 (TRPV1)激动剂,EC50为 75 nM,显示出对大麻素 1 型受体 (CB1) 的弱配体活性 (Ki=4.9 μM)。
T11799 L-745870 hydrochloride

Dopamine Receptor GPCR/G Protein; Neuroscience
L-745870 hydrochloride 是可透过血脑屏障的、选择性的、具有口服活性的多巴胺 D4受体拮抗剂,Ki=0.43 nM。它对 D2(Ki 为 960 nM) 和 D3(Ki 为 2300 nM) 受体的亲和力相对较弱,对 5-HT2受体,sigma 位点和 α-肾上腺素受体表现出中等亲和力。
T1913 MK-3697

OX Receptor GPCR/G Protein; Neuroscience
MK3697是OX2受体的一种高效选择性拮抗剂,Ki 值为0.95nM。
T22128 OU749

Transferase Metabolism
OU749 是一种 γ-谷氨酰转移酶 (GGT) 抑制剂,固有 Ki 值为 17.6 μM。
T7292 FITM

4-氟-N-[4-[6-(异丙基氨基)嘧啶-4-基]-1,3-噻唑-2-基]-N-甲基苯甲酰胺

GluR Neuroscience
FITM 是mGlu1受体的一种负变构调节剂,Ki 值为2.5 nM。
T6022 LY404039

pomaglumetad

Glucocorticoid Receptor; GluR Endocrinology/Hormones; Neuroscience
LY404039 (pomaglumetad) 是可口服的mGluR2和mGluR3选择性激动剂,有抗精神病和抗焦虑的作用。它对重组人mGluR2和mGluR3的Ki 分别为 149 和 92 nM,比对其他受体/转运蛋白的抑制性高 100 倍以上。
T22959 m-Chlorophenylbiguanide hydrochloride

1-(3-Chlorophenyl)biguanidehydrochloride,1-(3-氯苯基)双胍

5-HT Receptor GPCR/G Protein; Neuroscience
m-Chlorophenylbiguanide hydrochloride 是一种 5-HT3 受体激动剂。它选择性结合 5-HT3(Ki: 0.002 µM) 超过 5-HT1A(Ki: 10 µM) 和 5-HT2(Ki: 10 µM) 受体,但也结合多巴胺转运蛋白上的高亲和力和低亲和力位点( DAT;IC50:在大鼠尾状壳核突触体膜中分别为 0.4 和 34.8 µM)。
T5943 4,4'-DIMETHOXYBENZIL

p-Anisil,4,4'-二甲氧基苯酚酯

Others Others
4,4'-Dimethoxybenzil (trans-4-Sphingenine) 是人肠胃羧基酯酶抑制剂(Ki:70 nM)。
T7412 Tandospirone citrate

SM-3997 citrate,坦度螺酮柠檬酸盐,枸橼酸坦度螺酮

5-HT Receptor GPCR/G Protein; Neuroscience
Tandospirone citrate (SM-3997 citrate) 是一种选择性5-HT1A 受体激动剂,Ki 为27 nM。
T5047 PD-168077 maleate

Dopamine Receptor GPCR/G Protein; Neuroscience
PD-168077 maleate 是多巴胺 D4受体选择性激动剂,其 Ki=9 nM。
T26690 AVN-101

5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
AVN-101 是一种非常有效的 5-HT7 受体拮抗剂 (Ki = 153 pM)。 AVN-101 还对组胺 H1 (Ki = 0.58 nM) 和肾上腺素能 α2A、α2B 和 α2C (Ki = 0.41-3.6 nM) 受体表现出相当高的亲和力。 AVN-101在中枢神经系统疾病动物模型中显示出良好的口服生物利用度和促进脑血屏障通透性、低毒性和合理的疗效。

化合物

KI-7
Cat.No: T9238
Synonym:
Target: Adenosine Receptor
KI696
Cat.No: T11758L
Synonym:
Target: Nrf2
KI8751
Cat.No: T2446
Synonym:
Target: EGFR, VEGFR, FGFR, PDGFR, c-Kit
KI696 isomer
Cat.No: T11758
Synonym:
Target: Nrf2
Ki16425
Cat.No: T6108
Synonym: Debio 0719
Target: LPA Receptor, LPL Receptor
Ki16198
Cat.No: T6347
Synonym:
Target: LPA Receptor, LPL Receptor
Ki20227
Cat.No: T4315
Synonym: N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲
Target: c-Fms, VEGFR, CSF-1R, PDGFR, c-Kit
KI-328
Cat.No: T68313
Synonym:
Target:
Ki23057
Cat.No: T69162
Synonym:
Target:
FAP-PI3KI1
Cat.No: T74402
Synonym:
Target:
CAY 10465
Cat.No: T4607
Synonym: CAY10465,CAY10465 Exclusive
Target: AhR, Aryl Hydrocarbon Receptor
AGN 196996
Cat.No: T10261
Synonym:
Target: Others, Retinoid Receptor, Autophagy
LAS38096
Cat.No: T27800
Synonym: LAS 38096,LAS-38096
Target: Adenosine Receptor
CGP71683 hydrochloride
Cat.No: T5587
Synonym: CGP71683A,盐酸CGP71683
Target: Neuropeptide Y Receptor
lumateperone Tosylate
Cat.No: TQ0084
Synonym: ITI-007,Lumateperone甲苯磺酸盐
Target: Dopamine Receptor, 5-HT Receptor
Laropiprant
Cat.No: T15712
Synonym: MK-0524
Target: Prostaglandin Receptor
Vipadenant
Cat.No: T2373
Synonym: CEB-4520,BIIB-014
Target: Adenosine Receptor
Benzolamide
Cat.No: T23782
Synonym: CL-11366,W 1803,CL 11366,CL11366,苯唑拉胺,W-1803
Target: Carbonic Anhydrase
L-371,257
Cat.No: T15682
Synonym:
Target: Oxytocin Receptor, Vasopressin Receptor
Thioperamide maleate
Cat.No: T41247
Synonym: MR-12842 maleate,硫丙咪胺马来酸
Target: Histamine Receptor
IRL-1620 acetate
Cat.No: T15595L
Synonym: IRL-1620 acetate(142569-99-1 free base)
Target: Endothelin Receptor
NOS1-IN-1
Cat.No: T37696
Synonym: nNOS Inhibitor I
Target: NOS
EST73502 HCl
Cat.No: T39284
Synonym:
Target: Opioid Receptor
Fananserin
Cat.No: T15270
Synonym: RP 62203,法南色林
Target: Dopamine Receptor, 5-HT Receptor
AL 082D06
Cat.No: T1749
Synonym: D-06,AL082D06
Target: Glucocorticoid Receptor
A-3 hydrochloride
Cat.No: T14069
Synonym:
Target: CaMK, Casein Kinase, PKA, PKC
PF-04979064
Cat.No: T7343
Synonym:
Target: PI3K, mTOR
S1RA
Cat.No: T1865
Synonym: E-52862,4-(2-((5-甲基-1-(2-萘基)-1H-吡唑-3-基)氧基)乙基)吗啉
Target: Sigma receptor
Drofenine hydrochloride
Cat.No: T0713
Synonym: 盐酸六氢芬宁,Hexahydroadiphenine hydrochloride
Target: AChE
Facinicline hydrochloride
Cat.No: T28531
Synonym: RG3487
Target: 5-HT Receptor, AChR
PHT-427
Cat.No: T2420
Synonym: PHT 427,CS-0223
Target: Apoptosis, Akt, PDK
XP-59
Cat.No: T8419
Synonym:
Target: SARS-CoV
AKR1C1-IN-1
Cat.No: T14151
Synonym:
Target: NADPH
SB-3CT
Cat.No: T2009
Synonym:
Target: MMP
LY2955303
Cat.No: T15811
Synonym:
Target: Others, Retinoid Receptor
CAY10595
Cat.No: T10691
Synonym:
Target: GPR
Et-29
Cat.No: T35347
Synonym: NRD167
Target: Sirtuin
LY310762
Cat.No: T2688
Synonym: LY310762 HCl
Target: 5-HT Receptor
U-104
Cat.No: T2017
Synonym: NSC-213841,MST-104
Target: Carbonic Anhydrase
OMDM-5
Cat.No: T12306
Synonym:
Target: Cannabinoid Receptor, Endogenous Metabolite, TRP/TRPV Channel
L-745870 hydrochloride
Cat.No: T11799
Synonym:
Target: Dopamine Receptor
MK-3697
Cat.No: T1913
Synonym:
Target: OX Receptor
OU749
Cat.No: T22128
Synonym:
Target: Transferase
FITM
Cat.No: T7292
Synonym: 4-氟-N-[4-[6-(异丙基氨基)嘧啶-4-基]-1,3-噻唑-2-基]-N-甲基苯甲酰胺
Target: GluR
LY404039
Cat.No: T6022
Synonym: pomaglumetad
Target: Glucocorticoid Receptor, GluR
m-Chlorophenylbiguanide hydrochloride
Cat.No: T22959
Synonym: 1-(3-Chlorophenyl)biguanidehydrochloride,1-(3-氯苯基)双胍
Target: 5-HT Receptor
4,4'-DIMETHOXYBENZIL
Cat.No: T5943
Synonym: p-Anisil,4,4'-二甲氧基苯酚酯
Target: Others
Tandospirone citrate
Cat.No: T7412
Synonym: SM-3997 citrate,坦度螺酮柠檬酸盐,枸橼酸坦度螺酮
Target: 5-HT Receptor
PD-168077 maleate
Cat.No: T5047
Synonym:
Target: Dopamine Receptor
AVN-101
Cat.No: T26690
Synonym:
Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Cat. No. Product Name Target Signaling Pathways
T2922 Phlorizin

Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin

ATPase; SGLT GPCR/G Protein; Membrane transporter/Ion channel
Phlorizin (Phloridzin) 是非选择性的SGLT 抑制剂,也是Na+/K+-ATPase 抑制剂,对于hSGLT1和hSGLT2的Ki 值分别为 300 和 39 nM。
T4S2354 Dimethylfraxetin

二甲基白蜡树亭,Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin

Carbonic Anhydrase Metabolism
Dimethylfraxetin (6,7,8-Trimethoxycoumarin) 是Carbonic anhydrase 抑制剂(Ki:0.0097 μM)。
T8182 Guanfu base A

Guan-fu base A,关附甲素

P450; Potassium Channel; HER Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Tyrosine Kinase/Adaptors
Guanfu base A 是一种生物碱,分离自 Aconitum coreanum,是非竞争性 CYP2D6抑制剂,对人肝微粒体 (HLM) 的 Ki 为 1.20 μM,对人重组体 (rCYP2D6) 的 Ki 为 0.37 μM。它也是 CYP2D 的有效竞争抑制剂。它还能抑制 HERG 通道电流。Guan-fu base A 具有抗心律失常的作用。
T9605 Sangivamycin

BA-90912,桑霉素,NSC 65346

Nucleoside Antimetabolite/Analog; PKC Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。
T8260 4',5-Dihydroxyflavone

Lipoxygenase; Glucosidase Metabolism
4',5-Dihydroxyflavone 是大豆 LOX-1,Ki=102.6 μM。它也是一种酵母 α-葡萄糖苷酶抑制剂,IC50=66 μM。
TN5752 Isorhapontin

Antifungal Microbiology/Virology
Isorhapontin 抑制木霉属纤维二糖水解酶 I (Ki = 57.2 μM) 和木霉属内切葡聚糖酶 I 的活性。Isorhapontin 具有抗真菌活性。
T2209 Serotonin hydrochloride

5-HT hydrochloride,5-羟基色胺盐酸盐,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride

5-HT Receptor; Endogenous Metabolite; Transferase GPCR/G Protein; Metabolism; Neuroscience
Serotonin hydrochloride (Serotonin HCl) 是一种内源性 5-HT 受体激动剂、CNS 中的单胺神经递质和儿茶酚 O-甲基转移酶 (COMT) 抑制剂,Ki 值为 44 μM。
T15686 L-741626

3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole

Dopamine Receptor GPCR/G Protein; Neuroscience
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) 是D2多巴胺受体选择性拮抗剂,对人 D2、D3 和 D4 受体的Ki 分别为 2.4、100 和 220 nM。
T4429 Rauwolscine hydrochloride

Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂,Ki=12 nM。
T8373 6-Diazo-5-oxo-L-nor-Leucine

DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine

Influenza Virus; Glutaminase; Antibacterial; Antibiotic Microbiology/Virology; Proteases/Proteasome
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) 是一种谷氨酰胺拮抗剂,具有抗菌、抗病毒和抗癌作用,其Ki 值为 6 μM。它能降低肿瘤细胞的自我更新能力和转移能力 ,在体外表现出遗传毒性。
TN1160 1,2,3,6-Tetragalloylglucose

1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG

LDL; UGT Metabolism
1,2,3,6-Tetragalloylglucose (TeGG) 是 UDP-葡萄糖醛酸转移酶 1 家族成员,是多肽A1 的抑制剂(Ki:1.68 μM)。
TN1472 Cassiaside

Beta-Secretase; BACE Neuroscience
Cassiaside 是一种萘甲酮糖苷,抑制 BACE1 (IC50= 4.45 μM; Ki=9.85 μM)。Cassiaside 对半乳糖胺损伤具有明显的肝脏保护作用, 具有潜在的抗阿尔茨海默病 (AD) 活性。
T5648 Purpurin

吡啉,1,2,4-Trihydroxyanthraquinone,Hydroxylizaric acid,Verantin

MAO; Antibacterial; Antibiotic; Antifungal Metabolism; Microbiology/Virology; Neuroscience
Purpurin (Verantin) 是来自Rubia tinctorumL. 的天然蒽醌,具有抗抑郁样作用。
T0687 Simvastatin

辛伐他汀,MK-0733,MK 733

Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy Apoptosis; Autophagy; Metabolism
Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM),具有口服活性。Simvastatin 具有降血脂活性,可以抑制肝脏产生胆固醇,还可以用于预防心血管疾病。
T6856 Halofuginone

卤夫酮,常山酮,Tempostatin,empostatin,RU-19110

Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Stem Cells
Halofuginone (RU-19110) 是Febrifugine 的衍生物,是一种竞争性脯氨酰-tRNA 合成酶抑制剂。它也是肺血管扩张剂,可激活Kv 通道并阻断电压门控、受体操作和存储操作的钙离子通道。它具有抗炎、抗癌、抗疟疾和抗纤维化作用。
TN1016 Kukoamine A

NF-κB; Lipoxygenase; DNA/RNA Synthesis; Parasite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB
Kukoamine A 是一种天然的精胺衍生物,具有抗癌、抗高血压、细胞保护、抗氧化和抗炎活性。它是锥虫硫磷还原酶抑制剂,Ki 值为 1.8 μM。
TN3013 4,5-Dimethoxycanthin-6-one

Methylnigakinone

P450; Antibacterial; PDE Metabolism; Microbiology/Virology
4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂(IC50 : 1.7 μM, Ki : 2.6 μM),对环磷酸腺苷(cAMP)磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性,对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。
TN1120 Osthenol

MAO; Monoamine Oxidase Metabolism; Neuroscience
Osthenol 是一种前酰化香豆素,从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用,IC50=0.74 µM,对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的,选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
T10941 D-Ribonolactone

D-(+)-核糖酸-1,4-内酯,D-核糖内酯

Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology
D-Ribonolactone 是一种大肠杆菌 β-半乳糖苷酶的抑制剂,Ki 为 26 mM。它也一种糖内酯。
T4000 (±)-Equol

Equol,(±)-雌马酚,(R,S)-Equol

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite Endocrinology/Hormones; Metabolism
(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。
T2144 Tacrolimus

他克莫司,Fujimycin,FK506,FR900506

Phosphatase; Others; Antibacterial; Antibiotic; mTOR; Autophagy Autophagy; Metabolism; Microbiology/Virology; Others; PI3K/Akt/mTOR signaling
Tacrolimus (Fujimycin) 可与 FKBP12 结合形成高亲和力复合物 (Ki: 0.2 nM),抑制钙/钙调蛋白依赖性蛋白磷酸酶的活性。
TN1736 Hibifolin

棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷

Adenosine deaminase Metabolism
Hibifolin 是一种黄酮醇糖苷,是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。
TN1849 Kuwanon H

GPR; Bombesin Receptor Endocrinology/Hormones; GPCR/G Protein
Kuwanon H 是分离自桑白皮的黄酮类化合物,具有拮抗非肽类蛙皮素受体的活性。Kuwanon H 特异性抑制细胞内胃泌激素释放肽 CRP 与GRP-preferring 受体的结合,Ki 为 290 nM。
T6430 Calcifediol

25-羟基维生素 D3,U 32070E,25-hydroxy Vitamin D3,RO 8-8892,骨化二醇

Endogenous Metabolite Metabolism
Calcifediol (U 32070E) 是由维生素 D3 在肝中经羟基化后得到的前激素,是 VDR 的有效抑制剂。
T5081 Adenine monohydrochloride hemihydrate

腺嘌呤盐酸盐,Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate

Endogenous Metabolite; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Adenine monohydrochloride hemihydrate 是内源性代谢产物的一种。
TQ0296L N-Nornuciferine hydrochloride(4846-19-9 free base)

N-Nornuciferine hydrochloride

P450 Metabolism
N-Nornuciferine hydrochloride(4846-19-9 free base) (N-Nornuciferine hydrochloride) 是荷叶中的一种 aporphine 生物碱,显着抑制 CYP2D6(IC50:3.76 μM,Ki:2.34 μM)。
TN3748 D-Asparagine

D-天冬酰胺,H-D-Asn-OH

Others; Endogenous Metabolite Metabolism; Others
D-Asparagine (H-D-Asn-OH) 是酵母菌株的氮源。 D-Asparagine 是 L-Asparagine 水解的竞争性抑制剂 (Ki = 0.24 mM)。
T10191L 7-Chlorokynurenic acid

7-chloro-4-hydroxy-2-carboxyquinoline,7-氯犬尿酸,7-CKA

GluR; NMDAR Neuroscience
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) 是一种有效的选择性 NMDA 受体拮抗剂,对甘氨酸 B 激动剂位点的 IC50 为 0.56 μM。 7-Chlorokynurenic acid 抑制谷氨酸再摄取到突触小泡中,Ki 为 0.59 μM,并在神经轴输送后显示出镇痛作用。
T2926 Schizandrin A

P450; Virus Protease; Autophagy Autophagy; Metabolism; Microbiology/Virology
Schisandrin A 是一种从东方药物五味子中提取的主要有效成分,抑制 CYP3A 活性,IC50 分别为 6.60 μM 和 Ki 为 5.83 μM。
T2770 Gentiopicroside

Gentiopicrin,龙胆苦甙,龙胆苦苷

P450; HCV Protease Metabolism; Microbiology/Virology; Proteases/Proteasome
Gentiopicroside (Gentiopicrin) 是天然环烯醚萜苷,具有抗炎和抗氧化活性。它抑制P450的活性,对 CYP2A6 的 IC50和 Ki 值分别为 61 µM 和 22.8 µM,
TN1650 Friedelin

软木三萜酮,无羁萜

P450; NOS; Caspase; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Proteases/Proteasome
Friedelin 是分离自 Maytenus ilicifolia(Mart) 的叶子。它是 CYP3A4的非竞争性抑制剂,其 IC50和 Ki 分别为10.79 μM 和 6.16 μM,也是 CYP2E1的竞争性抑制剂,其 IC50和 Ki 分别为 22.54 μM 和 18.02 μM。
T13539 Allopurinol riboside

Others; Endogenous Metabolite; Parasite; Drug Metabolite Metabolism; Microbiology/Virology; Others
Allopurinol riboside 是别嘌醇的代谢产物,具有抗寄生虫作用。 Allopurinol riboside 竞争性抑制嘌呤核苷磷酸化酶对肌苷的作用,Ki 为 277 μM。
T5564 Tricarballylic acid

β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸

aconitase; Mitochondrial Metabolism Metabolism
Tricarballylic acid (Carballylic acid) 是三碳烯丙酸酯的共轭酸,是一种乌头酸水合酶的竞争性抑制剂,其 Ki= 0.52 mM。
T5568 H-Tyr(3-I)-OH

3-碘-L-酪氨酸,3-Iodo-L-tyrosine

Endogenous Metabolite Metabolism
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) 是酪氨酸羟化酶抑制剂和甲状腺激素 的中间体。
T14853 Cabergoline

FCE-21336,卡麦角林

Dopamine Receptor; 5-HT Receptor; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Cabergoline (FCE-21336) 是一种麦角衍生的多巴胺 D2亚类受体激动剂,高亲和力作用于D2、D3和5-HT2B 受体,Ki 分别为 0.7、1.5 和 1.2。
T7671 Myosmine

麦司明,麦斯明

Others; AChR Neuroscience; Others
Myosmine 是存在于木贼中的一种烟草生物碱,对 a4b2 烟碱乙酰胆碱受体具有低亲和力,Ki 值为 3300 nM。
T5S0669 Bergamottin

5-Geranoxypsoralen,Bergamotine,Bergaptin,佛手柑素

P450 Metabolism
Bergamottin (5-Geranoxypsoralen) 是竞争性CYP1A1抑制剂(Ki:10.703 nM)。
T2O2744 alpha-Naphthoflavone

苯并黄素;α-萘黄酮;7,8-苯并黄酮,7,8-benzoflavone,α-萘黄酮

Aromatase Endocrinology/Hormones
alpha-Naphthoflavone (7,8-benzoflavone) 是合成的黄酮类化合物,是一种竞争性芳香酶抑制剂,其IC50=0.5 μM,Ki=0.2 μM。
T5S0994 N-Methylcytisine

N-甲基野靛碱,Caulophylline

Others; AChR Neuroscience; Others
N-Methylcytisine (Caulophylline) 是苦参中的一种三环喹啉类生物碱,具有降血糖、缓解疼痛和抗炎活性。它是中枢神经系统中乙酰胆碱烟碱受体的选择性配体,对鱿鱼视神经节中的烟碱乙酰胆碱受体具有很高的亲和力,Kd 为 50 nM。
T3149 Salvianolic Acid C

丹酚酸C,丹酚酸 C

Others; P450 Metabolism; Others
Salvianolic acid C 是一种细胞色素 P4502C8(CYP2C8)的非竞争性抑制剂及细胞色素 P4502J2(CYP2J2)中等强度的混合抑制剂,对 CYP2C8 和 CYP2J2 的 Ki 分别为 4.82 μM 和 5.75 μM。
TN2268 Tetrahydromagnolol

Cannabinoid Receptor; GPR; GABA Receptor Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
Tetrahydromagnolol 是 Magnolol 的主要代谢产物,是一种弱的GPR55受体拮抗剂。它是选择性大麻素CB2受体激动剂,EC50为 170 nM,Ki 为 416 nM,对CB2受体的选择性比 CB1 受体高 20 倍。
T1310 2-Thiouracil

Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶

Thyroid hormone receptor(THR); NO Synthase Endocrinology/Hormones; Immunology/Inflammation
2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM),是一种抗甲状腺化合物,可用作高度特异性的黑色素瘤探测物。
T4S0051 Coptisine sulfate

Indoleamine 2,3-Dioxygenase (IDO) Metabolism
Coptisine Sulfate 是一种从黄连中分离到的生物碱,是非竞争性的IDO 抑制剂,Ki=为 5.8 μM,IC50=6.3 μM。
T1717 alpha-Mangostin

α-倒捻子素,α-Mangostin,Mangostin

Apoptosis; Virus Protease; Dehydrogenase; Reactive Oxygen Species; Antibacterial; Antifungal Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
alpha-Mangostin (Mangostin) 是有多种生物活性的膳食呫吨酮。它是一种IDH1突变体的抑制剂,Ki 值为 2.85 μM。
T7472 7-Hydroxyflavone

7-羟基黄酮,7羟基黄酮

P450 Metabolism
7-Hydroxyflavone 是一种黄酮类化合物,从M. indica 中分离得到,具有抗炎活性。它利用 ERK/Nrf2/HO-1 通路保护肾细胞,使其免受尼古丁诱导的细胞毒性。
T1711 Harmine

Telepathine,去氢骆驼蓬碱

MAO; 5-HT Receptor; DYRK Cell Cycle/Checkpoint; GPCR/G Protein; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
Harmine (Telepathine) 是一种从山茱萸种子中分离出来的生物碱,具有抗癌和抗炎活性。它是双特异性酪氨酸磷酸化调节激酶抑制剂,对5-HT2A 血清素受体具有高亲和力,Ki 值为 397 nM。
T20712 Conessine

Conessinum,Wrightine,地麻素,Roquessine,Neriine,Konessin

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Conessine (Conessinum) 是一种具有抗疟活性的甾体生物碱,是高效选择性H3 受体拮抗剂,对于人、狗、豚鼠和大鼠 H3受体的Ki 分别为 5.4、6.0、5.7 和 25 nM。
T4S0145 Corylifol A

Corylinin,补骨脂异黄酮A

hCE; STAT; UGT JAK/STAT signaling; Metabolism; Stem Cells
Corylifol A (Corylinin) 是补骨脂中的一种天然产物,可抑制IL-6 诱导的STAT3激活和磷酸化,IC50值为0.81 μM。
T11218 ε-​Viniferin

epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体

P450 Metabolism
ε-​Viniferin (epsilon-Viniferin) 提取自 Vitis vinifera,是 Resveratrol 的二聚体,能够抑制 CYP 家族,其 Ki=0.5~20 μM,具有抗氧化作用。
T1270 Vincristine sulfate

Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate,硫酸长春新碱

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Vincristine sulfate (Leurocristine sulfate) 是一种抗肿瘤长春花生物碱。在细胞周期的 S 期不可逆地与微管(Ki: 85 nM) 和纺锤体蛋白结合,并干扰有丝分裂纺锤体的形成。
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天然产物

Phlorizin
Cat.No: T2922
Synonym: Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin
Target: ATPase, SGLT
Dimethylfraxetin
Cat.No: T4S2354
Synonym: 二甲基白蜡树亭,Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin
Target: Carbonic Anhydrase
Guanfu base A
Cat.No: T8182
Synonym: Guan-fu base A,关附甲素
Target: P450, Potassium Channel, HER
Sangivamycin
Cat.No: T9605
Synonym: BA-90912,桑霉素,NSC 65346
Target: Nucleoside Antimetabolite/Analog, PKC
4',5-Dihydroxyflavone
Cat.No: T8260
Synonym:
Target: Lipoxygenase, Glucosidase
Isorhapontin
Cat.No: TN5752
Synonym:
Target: Antifungal
Serotonin hydrochloride
Cat.No: T2209
Synonym: 5-HT hydrochloride,5-羟基色胺盐酸盐,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride
Target: 5-HT Receptor, Endogenous Metabolite, Transferase
L-741626
Cat.No: T15686
Synonym: 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
Target: Dopamine Receptor
Rauwolscine hydrochloride
Cat.No: T4429
Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride
Target: Adrenergic Receptor
6-Diazo-5-oxo-L-nor-Leucine
Cat.No: T8373
Synonym: DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine
Target: Influenza Virus, Glutaminase, Antibacterial, Antibiotic
1,2,3,6-Tetragalloylglucose
Cat.No: TN1160
Synonym: 1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG
Target: LDL, UGT
Cassiaside
Cat.No: TN1472
Synonym:
Target: Beta-Secretase, BACE
Purpurin
Cat.No: T5648
Synonym: 吡啉,1,2,4-Trihydroxyanthraquinone,Hydroxylizaric acid,Verantin
Target: MAO, Antibacterial, Antibiotic, Antifungal
Simvastatin
Cat.No: T0687
Synonym: 辛伐他汀,MK-0733,MK 733
Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy
Halofuginone
Cat.No: T6856
Synonym: 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Kukoamine A
Cat.No: TN1016
Synonym:
Target: NF-κB, Lipoxygenase, DNA/RNA Synthesis, Parasite
4,5-Dimethoxycanthin-6-one
Cat.No: TN3013
Synonym: Methylnigakinone
Target: P450, Antibacterial, PDE
Osthenol
Cat.No: TN1120
Synonym:
Target: MAO, Monoamine Oxidase
D-Ribonolactone
Cat.No: T10941
Synonym: D-(+)-核糖酸-1,4-内酯,D-核糖内酯
Target: Endogenous Metabolite, Antibacterial
(±)-Equol
Cat.No: T4000
Synonym: Equol,(±)-雌马酚,(R,S)-Equol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite
Tacrolimus
Cat.No: T2144
Synonym: 他克莫司,Fujimycin,FK506,FR900506
Target: Phosphatase, Others, Antibacterial, Antibiotic, mTOR, Autophagy
Hibifolin
Cat.No: TN1736
Synonym: 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷
Target: Adenosine deaminase
Kuwanon H
Cat.No: TN1849
Synonym:
Target: GPR, Bombesin Receptor
Calcifediol
Cat.No: T6430
Synonym: 25-羟基维生素 D3,U 32070E,25-hydroxy Vitamin D3,RO 8-8892,骨化二醇
Target: Endogenous Metabolite
Adenine monohydrochloride hemihydrate
Cat.No: T5081
Synonym: 腺嘌呤盐酸盐,Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate
Target: Endogenous Metabolite, Adenosine Receptor
N-Nornuciferine hydrochloride(4846-19-9 free base)
Cat.No: TQ0296L
Synonym: N-Nornuciferine hydrochloride
Target: P450
D-Asparagine
Cat.No: TN3748
Synonym: D-天冬酰胺,H-D-Asn-OH
Target: Others, Endogenous Metabolite
7-Chlorokynurenic acid
Cat.No: T10191L
Synonym: 7-chloro-4-hydroxy-2-carboxyquinoline,7-氯犬尿酸,7-CKA
Target: GluR, NMDAR
Schizandrin A
Cat.No: T2926
Synonym:
Target: P450, Virus Protease, Autophagy
Gentiopicroside
Cat.No: T2770
Synonym: Gentiopicrin,龙胆苦甙,龙胆苦苷
Target: P450, HCV Protease
Friedelin
Cat.No: TN1650
Synonym: 软木三萜酮,无羁萜
Target: P450, NOS, Caspase, Prostaglandin Receptor
Allopurinol riboside
Cat.No: T13539
Synonym:
Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite
Tricarballylic acid
Cat.No: T5564
Synonym: β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸
Target: aconitase, Mitochondrial Metabolism
H-Tyr(3-I)-OH
Cat.No: T5568
Synonym: 3-碘-L-酪氨酸,3-Iodo-L-tyrosine
Target: Endogenous Metabolite
Cabergoline
Cat.No: T14853
Synonym: FCE-21336,卡麦角林
Target: Dopamine Receptor, 5-HT Receptor, Autophagy
Myosmine
Cat.No: T7671
Synonym: 麦司明,麦斯明
Target: Others, AChR
Bergamottin
Cat.No: T5S0669
Synonym: 5-Geranoxypsoralen,Bergamotine,Bergaptin,佛手柑素
Target: P450
alpha-Naphthoflavone
Cat.No: T2O2744
Synonym: 苯并黄素;α-萘黄酮;7,8-苯并黄酮,7,8-benzoflavone,α-萘黄酮
Target: Aromatase
N-Methylcytisine
Cat.No: T5S0994
Synonym: N-甲基野靛碱,Caulophylline
Target: Others, AChR
Salvianolic Acid C
Cat.No: T3149
Synonym: 丹酚酸C,丹酚酸 C
Target: Others, P450
Tetrahydromagnolol
Cat.No: TN2268
Synonym:
Target: Cannabinoid Receptor, GPR, GABA Receptor
2-Thiouracil
Cat.No: T1310
Synonym: Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶
Target: Thyroid hormone receptor(THR), NO Synthase
Coptisine sulfate
Cat.No: T4S0051
Synonym:
Target: Indoleamine 2,3-Dioxygenase (IDO)
alpha-Mangostin
Cat.No: T1717
Synonym: α-倒捻子素,α-Mangostin,Mangostin
Target: Apoptosis, Virus Protease, Dehydrogenase, Reactive Oxygen Species, Antibacterial, Antifungal
7-Hydroxyflavone
Cat.No: T7472
Synonym: 7-羟基黄酮,7羟基黄酮
Target: P450
Harmine
Cat.No: T1711
Synonym: Telepathine,去氢骆驼蓬碱
Target: MAO, 5-HT Receptor, DYRK
Conessine
Cat.No: T20712
Synonym: Conessinum,Wrightine,地麻素,Roquessine,Neriine,Konessin
Target: Histamine Receptor
Corylifol A
Cat.No: T4S0145
Synonym: Corylinin,补骨脂异黄酮A
Target: hCE, STAT, UGT
ε-​Viniferin
Cat.No: T11218
Synonym: epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体
Target: P450
Vincristine sulfate
Cat.No: T1270
Synonym: Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate,硫酸长春新碱
Target: Apoptosis, Microtubule Associated
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Cat. No. Product Name Species Expression System
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor superfamily, member 8...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-03105 Ki67/MKI67 Protein, Human, Recombinant (GST)

MIB-1,PPP1R105,marker of proliferation Ki-67,MIB-,<...

Human E. coli
MKI67 contains 1 FHA domain and plays a key role in cell proliferation. During interphase, the MKI67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. MKI67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells. MKI67 is an excellent marker to determine the growth fraction of a given cell population. The fraction of MKI67-positive tu...
TMPY-05443 CD30/TNFRSF8 Protein, Mouse, Recombinant (His)

Ki-1,Ki,D1S166E,Cd30,tumor necrosis factor...

Mouse HEK293 Cells
CD30/TNFRSF8 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q60846.
TMPY-05737 CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc)

Cd30,Ki,tumor necrosis factor receptor superfamily,...

Mouse HEK293 Cells
CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.92 kDa and the accession number is Q60846.
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His)

KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...

Human E. coli
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-04116 KRAS Protein,Human,Recombinant(G12C & Q61H, His)

NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2B,K-RAS,Kirsten...

Human E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His)

KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene ho...

Human E. coli
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,KRAS2,

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPJ-01436 MKI67 Protein, Human, Recombinant (GST)

Ki-67,Antigen Ki67,MKI67,KI

Human E. coli
MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition...
TMPY-05471 CD30/TNFRSF8 Protein, Human, Recombinant (hFc)

Ki-1,tumor necrosis factor receptor superfamily, me...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.2 kDa and the accession number is P28908-1.
TMPY-06282 CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated

tumor necrosis factor receptor superfamily, member 8,Ki<...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 67.02 kDa and the accession number is P28908-1.
TMPY-03614 PSME3 Protein, Human, Recombinant (His)

PA28G,PA28-gamma,HEL-S-283,REG-GAMMA,proteasome (prosome, ma...

Human E. coli
PSME3, also known as PA28-gamma, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase su...
TMPY-05118 CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated

D1S166E,Ki-1,tumor necrosis factor receptor superfa...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.9 kDa and the accession number is P28908-1.
TMPY-06430 CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated

Ki-1,CD30,D1S166E,tumor necrosis factor receptor su...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.74 kDa and the accession number is P28908-1.
TMPJ-00510 KRAS Protein, Human, Recombinant (G12C, His)

RASK2,c-K-ras,CFC2,KRAS2,Ki-Ras

Human E. coli
KRAS Protein, Human, Recombinant (G12C, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26 KDa and the accession number is AAH13572.1.
TMPJ-00511 KRAS Protein, Human, Recombinant (G12V, His)

KRAS2,RASK2,c-K-ras,Ki-Ras,CFC2

Human E. coli
KRAS Protein, Human, Recombinant (G12V, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25-30 KDa and the accession number is AAH13572.1.
TMPK-00078 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled

TNFSF7, Ki-24 antigen,CD70,TNFSF7G,CD70 molecule,CD...

Human HEK293 Cells
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51.8 kDa and ...
TMPK-00080 CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

CD27-L,CD70 molecule,TNFSF7G,CD70,CD27LG,CD27 Ligand,TNFSF7,...

Human HEK293 Cells
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecula...
TMPK-00666 CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)

CD70 molecule,TNFSF7,CD70,TNFSF7G,CD27-L,CD27LG,CD27 Ligand,...

Cynomolgus HEK293 Cells
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.4 kDa and the accession nu...
TMPK-00079 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)

TNFSF7,CD27 Ligand, Ki-24 antigen,CD70 molecule,CD2...

Human HEK293 Cells
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51.8 kDa and the accession ...
TMPJ-00342 CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)

Lymphocyte activation antigen CD30,TNFRSF8,Tumor necrosis fa...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 60-95 KDa and the accession number is P28908.
TMPJ-00341 CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)

TNFRSF8,Ki-1 antigen,CD30,CD30L receptor,Tumor necr...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
TMPJ-00340 CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated

Lymphocyte activation antigen CD30,TNFRSF8,CD30,Ki-...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is P28908.
TMPJ-00343 CD30/TNFRSF8 Protein, Human, Recombinant (mFc)

TNFRSF8,Tumor necrosis factor receptor superfamily member 8,...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
TMPJ-00240 CAMK1 Protein, Human, Recombinant (His)

CaM Kinase I Alpha,CaMKI-α,CaM Ki...

Human HEK293 Cells
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed. CAMK1 is phosphorylated by CaMKK1 and CaMKK2 on Thr-177. CAMK1 regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization, and neurite outgrowth. CAMK1 plays a role in K+ and ANG2-mediated regulation of the aldo...
TMPK-01428 HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi)

CFC2,K-RAS4B,K-Ras 2,C-K-RAS,RASK2,NS3,RALD,KI-RAS,...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01405 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

KI-RAS,RASK2,K-Ras 2,MHC,KRAS,KRAS1,NS3,K-RAS2A,K-R...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01443 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), FITC-Labeled

KRAS1,C-K-RAS,K-RAS4B,RALD,K-Ras 2,K-RAS2A,K-RAS2B,KRAS2,NS3...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01450 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS2B,K-Ras 2,C-K-RAS,RASK2,K-...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01462 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

K-RAS4A,K-RAS2A,CFC2,KRAS1,K-RAS4B,C-K-RAS,KRAS,K-RAS2B,K-Ra...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01511 HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

GTPase Kras,K-RAS4A,KI-RAS,K-RAS4B,C-K-RAS,K-Ras 2,...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01460 HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,K-RAS2A,KI-RAS,K-RAS4B,RALD,NS3,GTPase Kras,K-R...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01402 HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

KRAS1,NS,CFC2,K-RAS4B,RASK2,K-Ras 2,KI-RAS,GTPase K...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01430 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

K-RAS2A,RALD,NS3,K-Ras 2,KI-RAS,NS,MHC,K-RAS2B,K-RA...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01432 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Tetramer Protein, Human, MHC (His & Avi)

RASK2,K-RAS4A,K-RAS4B,KRAS2,CFC2,MHC,KRAS,KI-RAS,K-...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01440 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

RASK2,KI-RAS,C-K-RAS,KRAS,MHC,NS,K-RAS4A,K-RAS2B,CF...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01528 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)

KRAS1,MHC,K-RAS2B,K-RAS4B,NS,GTPase Kras,K-Ras 2,KI...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B,KI-RAS,K...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01512 HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)

K-Ras 2,NS,NS3,K-RAS2B,CFC2,MHC,KRAS1,GTPase Kras,K-RAS4A,KR...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01465 HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi)

NS3,K-RAS2A,CFC2,KRAS,GTPase Kras,K-RAS2B,K-Ras 2,KI

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01435 HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

KRAS2,NS3,RASK2,KI-RAS,RALD,K-RAS2B,K-RAS4B,GTPase ...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01438 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

RASK2,KRAS2,KRAS1,MHC,C-K-RAS,KI-RAS,K-RAS4B,RALD,K...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01507 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi)

K-RAS2A,K-RAS4B,KI-RAS,RALD,C-K-RAS,RASK2,NS,MHC,NS...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01427 HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

C-K-RAS,K-RAS4B,GTPase Kras,K-RAS4A,K-RAS2A,KRAS2,CFC2,RASK2...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01403 HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

K-Ras 2,KI-RAS,CFC2,KRAS1,GTPase Kras,KRAS,K-RAS4B,...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01399 HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

K-RAS2A,NS3,KRAS2,CFC2,K-RAS4B,GTPase Kras,RALD,MHC,KRAS,RAS...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01404 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

NS,KRAS,KRAS1,KRAS2,MHC,RALD,K-RAS4A,K-RAS2A,K-RAS4B,K-RAS2B...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01479 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

NS3,KRAS1,K-Ras 2,K-RAS2A,K-RAS2B,C-K-RAS,K-RAS4A,CFC2,KRAS2...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01525 HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CFC2,RALD,K-Ras 2,MHC,C-K-RAS,NS3,GTPase Kras,KRAS2,K-RAS4B,...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01461 HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi)

C-K-RAS,KRAS,RASK2,K-Ras 2,K-RAS2A,MHC,CFC2,K-RAS4B,K-RAS2B,...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
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重组蛋白

CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
Ki67/MKI67 Protein, Human, Recombinant (GST)
Cat.No: TMPY-03105
Species: Human
Expression System: E. coli
CD30/TNFRSF8 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05443
Species: Mouse
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05737
Species: Mouse
Expression System: HEK293 Cells
KRAS Protein,Human, Recombinant (Q61H, His)
Cat.No: TMPY-01888
Species: Human
Expression System: E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
Cat.No: TMPY-04116
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (G12D, His)
Cat.No: TMPY-06056
Species: Human
Expression System: E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
MKI67 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01436
Species: Human
Expression System: E. coli
CD30/TNFRSF8 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05471
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06282
Species: Human
Expression System: HEK293 Cells
PSME3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03614
Species: Human
Expression System: E. coli
CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05118
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06430
Species: Human
Expression System: HEK293 Cells
KRAS Protein, Human, Recombinant (G12C, His)
Cat.No: TMPJ-00510
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (G12V, His)
Cat.No: TMPJ-00511
Species: Human
Expression System: E. coli
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
Cat.No: TMPK-00078
Species: Human
Expression System: HEK293 Cells
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00080
Species: Human
Expression System: HEK293 Cells
CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00666
Species: Cynomolgus
Expression System: HEK293 Cells
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
Cat.No: TMPK-00079
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
Cat.No: TMPJ-00342
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
Cat.No: TMPJ-00341
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
Cat.No: TMPJ-00340
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
Cat.No: TMPJ-00343
Species: Human
Expression System: HEK293 Cells
CAMK1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00240
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01428
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01405
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), FITC-Labeled
Cat.No: TMPK-01443
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01450
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01462
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01511
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01460
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01402
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01430
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01432
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01440
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01528
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01456
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01512
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01465
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01435
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01438
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01507
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01427
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01403
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01399
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01404
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01479
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01525
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01461
Species: Human
Expression System: HEK293 Cells
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