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Targets Recommended: Antifolate Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Integrin Wnt/beta-catenin Melanin-concentrating Hormone Receptor (MCHR) NO Synthase Complement System PGE Synthase Antiviral Interleukin Fatty Acid Synthase Xanthine Oxidase Integrase Antibiotic Antifungal Antifection Anti-infection Antibacterial Huntingtin Antioxidant STAT

3356

抑制剂 & 化合物

720

天然产物

65

化合物库

25

TargetMol 试剂盒

11518

重组蛋白

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Cat. No. Product Name
L2620 神经退行性疾病化合物库

2154 compounds
2154 种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选;
L5700 精选片段库

246 compounds
246 个片段小分子的独特集合,可用于基于片段的筛选和药物发现(FBDD);
L2110 抗癌上市药物库

1779 compounds
1779 个具有抗癌活性小分子的独特集合,所有化合物都经过了严格的临床前研究和临床试验,由FDA、EMA 或NMPA 批准上市,可用于高通量、高内涵筛选。
L2191 抗乳腺癌化合物库

1939 compounds
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究;
L4300 Wnt/Hedgehog/Notch 通路化合物库

237 compounds
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。
L5900 血脑屏障通透化合物库

509 compounds
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L4510 抗寄生虫库

419 compounds
419 种具有抗寄生虫活性的小分子化合物;
L7500 凝血与抗凝化合物库

144 compounds
144 个化合物的独特集合,可用于高通量筛选和高内涵筛选;
L8800 药物片段库

1119 compounds
1119 种药物片段分子,是FBDD 方法新药筛选的有力工具;
L6740 抗结直肠癌中药单体化合物库

382 compounds
382 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具;
L2196 抗卵巢癌化合物库

1867 compounds
1867 种与卵巢癌相关的化合物,可以用于抗卵巢癌药物研发和药理研究
L2194 抗结直肠癌化合物库

1545 compounds
1545 种与结直肠癌相关的化合物,可以用于高通量和高内涵筛选;
L6730 抗病毒中药单体化合物库

268 compounds
268 种具有抗病毒活性的中药单体集合,是药物开发、药理研究的有效工具;
L2193 抗肝癌化合物库

1787 compounds
1787 种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究;
L2130 抗癌细胞代谢库

1268 compounds
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选;
L5200 抗代谢疾病化合物库

1544 compounds
1544 个代谢疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L7860 Mini片段亲电杂环化合物库

369 compounds
高溶解度共价杂环片段库中的 369 个化合物
L7810 高溶解性多官能团片段化合物库

1159 compounds
高溶解性多官能团片段库包含1159 种片段分子
L7840 高溶解性卤化片段化合物库

796 compounds
高溶解性卤化片段库包含796 个卤化片段化合物。
L4660 神经疾病库Plus

1246 compounds
1246 种神经系统相关、结构新颖的化合物;
L2120 抗癌临床化合物库

2545 compounds
2545 个具有抗癌活性小分子的独特集合,可用于高通量高内涵筛选。
L2150 抗癌药物库

3080 compounds
3080 个具有抗癌活性小分子的独特集合,生物活性已经临床前实验证实,可用于高通量、高内涵筛选;
L4600 植物来源化合物库

3048 compounds
3048 个植物来源天然产物的独特集合,来自277类植物的精心之选;
L7110 抗高血压化合物库

678 compounds
678 种高血压相关的小分子,用于高通量和高内涵筛选;
L6600 胃肠炎天然产物库

219 compounds
219 种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L7850 高溶解性3D结构多样性片段化合物库

1079 compounds
高溶解性3D 结构多样性片段库包含1079 个化合物。
L7800 高溶解性片段库

2728 compounds
2728 种片段分子合集,数量适中,是 FBDD 方法新药筛选的有力工具。
L6620 抗寄生虫天然产物库

253 compounds
253 个抗寄生虫相关的天然产物集合,是药物开发、药理研究的有效工具;
L6610 抗感染天然产物库

1060 compounds
1060 个抗感染相关的天然产物集合,是药物开发、药理研究的有效工具;
L2100 抗癌化合物库

7234 compounds
7234 种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L1800 抗感染化合物库

2938 compounds
2938 种具有抗感染活性的化合物的特有集合,包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性;
L2140 癌细胞分化化合物库

406 compounds
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2192 抗胰腺癌化合物库

2238 compounds
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选;
L6150 天然产物共价化合物库

583 compounds
提供产品的生物学信息和药物学信息,为筛选提供理论方向和研究基础;
L6710 中药抗炎分子库

1246 compounds
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具;
L6700 抗癌天然产物库

1772 compounds
1772 种已知活性天然产物的独特集合,是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具,可用于HTS 和HCS。
L9410 共价抑制剂库

1920 compounds
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发;
L8200 抗衰老化合物库

3279 compounds
3279 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2630 神经元分化化合物库

672 compounds
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发
L9900 药用辅料化合物库

182 compounds
182 种 FDA 批准药品中的非活性成分集合
L2195 抗前列腺癌化合物库

2070 compounds
2070 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选
L4520 抗菌活性库

904 compounds
904 种具有抗菌活性的化合物,是抗菌药物研发的有力工具;
L8000 干细胞分化化合物库

1197 compounds
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;
L4400 抗生素库

692 compounds
692 个具有抗菌活性化合物的独特集合,是医药研究的优良工具库和药物筛选的有效载体;
L7100 抗肥胖化合物库

2247 compounds
2247 个抗肥胖化合物的独特集合,可用于高通量筛选和高内涵筛选;
L7830 高溶解性片段药效团化合物库

985 compounds
高溶解性片段药效团库包含985 个片段小分子。
L2180 抗肿瘤库Plus

1468 compounds
1468 种抗肿瘤相关、结构新颖的化合物;
L1710 抗COVID-19化合物库

1133 compounds
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选;
L2160 抗癌活性化合物库

3188 compounds
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选;
L9411 半胱氨酸共价化合物库

70 compounds
半胱氨酸共价库包含 70 个化合物。
L4520 抗菌活性库

904 compounds
904 种具有抗菌活性的化合物,是抗菌药物研发的有力工具;
L8000 干细胞分化化合物库

1197 compounds
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;
L4400 抗生素库

692 compounds
692 个具有抗菌活性化合物的独特集合,是医药研究的优良工具库和药物筛选的有效载体;
L7100 抗肥胖化合物库

2247 compounds
2247 个抗肥胖化合物的独特集合,可用于高通量筛选和高内涵筛选;
L7830 高溶解性片段药效团化合物库

985 compounds
高溶解性片段药效团库包含985 个片段小分子。
L2180 抗肿瘤库Plus

1468 compounds
1468 种抗肿瘤相关、结构新颖的化合物;
L1710 抗COVID-19化合物库

1133 compounds
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选;
L2160 抗癌活性化合物库

3188 compounds
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选;
L9411 半胱氨酸共价化合物库

70 compounds
半胱氨酸共价库包含 70 个化合物。
L9860 抗抑郁症化合物库

1163 compounds
1163 种与抑郁症相关的化合物,可以用于高通量和高内涵筛选
L9810 抗纤维化化合物库

1180 compounds
1180 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选;
L2190 抗肺癌化合物库

1702 compounds
1702 种与肺癌相关的化合物,可以用于抗肺癌药物研发和药理研究;
L6720 抗COVID-19中药单体库

1147 compounds
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1147 种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具;
L1700 抗病毒库

1040 compounds
1040 种具有抗病毒活性的化合物的特有集合,是筛选新型抗病毒药的有效工具;可用于高通量筛选和高内涵筛选;
L2610 神经递质受体化合物库

1513 compounds
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选;

化合物库

神经退行性疾病化合物库
Cat.No: L2620
Compounds: 2154
精选片段库
Cat.No: L5700
Compounds: 246
抗癌上市药物库
Cat.No: L2110
Compounds: 1779
抗乳腺癌化合物库
Cat.No: L2191
Compounds: 1939
Wnt/Hedgehog/Notch 通路化合物库
Cat.No: L4300
Compounds: 237
血脑屏障通透化合物库
Cat.No: L5900
Compounds: 509
抗寄生虫库
Cat.No: L4510
Compounds: 419
凝血与抗凝化合物库
Cat.No: L7500
Compounds: 144
药物片段库
Cat.No: L8800
Compounds: 1119
抗结直肠癌中药单体化合物库
Cat.No: L6740
Compounds: 382
抗卵巢癌化合物库
Cat.No: L2196
Compounds: 1867
抗结直肠癌化合物库
Cat.No: L2194
Compounds: 1545
抗病毒中药单体化合物库
Cat.No: L6730
Compounds: 268
抗肝癌化合物库
Cat.No: L2193
Compounds: 1787
抗癌细胞代谢库
Cat.No: L2130
Compounds: 1268
抗代谢疾病化合物库
Cat.No: L5200
Compounds: 1544
Mini片段亲电杂环化合物库
Cat.No: L7860
Compounds: 369
高溶解性多官能团片段化合物库
Cat.No: L7810
Compounds: 1159
高溶解性卤化片段化合物库
Cat.No: L7840
Compounds: 796
神经疾病库Plus
Cat.No: L4660
Compounds: 1246
抗癌临床化合物库
Cat.No: L2120
Compounds: 2545
抗癌药物库
Cat.No: L2150
Compounds: 3080
植物来源化合物库
Cat.No: L4600
Compounds: 3048
抗高血压化合物库
Cat.No: L7110
Compounds: 678
胃肠炎天然产物库
Cat.No: L6600
Compounds: 219
高溶解性3D结构多样性片段化合物库
Cat.No: L7850
Compounds: 1079
高溶解性片段库
Cat.No: L7800
Compounds: 2728
抗寄生虫天然产物库
Cat.No: L6620
Compounds: 253
抗感染天然产物库
Cat.No: L6610
Compounds: 1060
抗癌化合物库
Cat.No: L2100
Compounds: 7234
抗感染化合物库
Cat.No: L1800
Compounds: 2938
癌细胞分化化合物库
Cat.No: L2140
Compounds: 406
抗胰腺癌化合物库
Cat.No: L2192
Compounds: 2238
天然产物共价化合物库
Cat.No: L6150
Compounds: 583
中药抗炎分子库
Cat.No: L6710
Compounds: 1246
抗癌天然产物库
Cat.No: L6700
Compounds: 1772
共价抑制剂库
Cat.No: L9410
Compounds: 1920
抗衰老化合物库
Cat.No: L8200
Compounds: 3279
神经元分化化合物库
Cat.No: L2630
Compounds: 672
药用辅料化合物库
Cat.No: L9900
Compounds: 182
抗前列腺癌化合物库
Cat.No: L2195
Compounds: 2070
抗菌活性库
Cat.No: L4520
Compounds: 904
干细胞分化化合物库
Cat.No: L8000
Compounds: 1197
抗生素库
Cat.No: L4400
Compounds: 692
抗肥胖化合物库
Cat.No: L7100
Compounds: 2247
高溶解性片段药效团化合物库
Cat.No: L7830
Compounds: 985
抗肿瘤库Plus
Cat.No: L2180
Compounds: 1468
抗COVID-19化合物库
Cat.No: L1710
Compounds: 1133
抗癌活性化合物库
Cat.No: L2160
Compounds: 3188
半胱氨酸共价化合物库
Cat.No: L9411
Compounds: 70
抗菌活性库
Cat.No: L4520
Compounds: 904
干细胞分化化合物库
Cat.No: L8000
Compounds: 1197
抗生素库
Cat.No: L4400
Compounds: 692
抗肥胖化合物库
Cat.No: L7100
Compounds: 2247
高溶解性片段药效团化合物库
Cat.No: L7830
Compounds: 985
抗肿瘤库Plus
Cat.No: L2180
Compounds: 1468
抗COVID-19化合物库
Cat.No: L1710
Compounds: 1133
抗癌活性化合物库
Cat.No: L2160
Compounds: 3188
半胱氨酸共价化合物库
Cat.No: L9411
Compounds: 70
抗抑郁症化合物库
Cat.No: L9860
Compounds: 1163
抗纤维化化合物库
Cat.No: L9810
Compounds: 1180
抗肺癌化合物库
Cat.No: L2190
Compounds: 1702
抗COVID-19中药单体库
Cat.No: L6720
Compounds: 1147
抗病毒库
Cat.No: L1700
Compounds: 1040
神经递质受体化合物库
Cat.No: L2610
Compounds: 1513
Cat. No. Product Name Form Specificity Of Inhibition
C0005 Cell Counting Kit-8 (CCK-8)

Cell Counting Kit-8 (CCK-8)

Solution in bottle
CL0124 AMPAR antagonist/activator kit

AMPAR antagonist/activator kit

CL0050 Antiparasitic compound kit

Antiparasitic compound kit

CL0096 Wnt/β-catenin/PORCN inhibitor/activator kit

Wnt/β-catenin/PORCN inhibitor/activator kit

CL0111 TLR agonist/antagonist kit

TLR agonist/antagonist kit

CL0086 Anti-dsDNA viruses compound kit

Anti-dsDNA viruses compound kit

C0111 Magrose Beads NTA-Nickel (Ultra-suspension)

His-tag 蛋白纯化磁珠 NTA-Ni

CL0073 DNA synthesis inhibitor/activator kit

DNA synthesis inhibitor/activator kit

CL0097 Prostaglandin Receptor antagonist/agonist kit

Prostaglandin Receptor antagonist/agonist kit

CL0049 Histamine Receptor antagonist kit

Histamine Receptor antagonist kit

CL0048 Anti-HIV compound kit

Anti-HIV compound kit

CL0047 AChR antagonist/agonist kit

AChR antagonist/agonist kit

CL0104 NMDAR agonist/antagonist kit

NMDAR agonist/antagonist kit

CL0090 RNA Synthesis inhibitor/activator kit

RNA Synthesis inhibitor/activator kit

CL0144 Endothelin Receptor antagonist kit

Endothelin Receptor antagonist kit

CL0051 Adrenergic Receptor antagonist/agonist kit

Adrenergic Receptor antagonist/agonist kit

CL0126 Androgen Receptor antagonist kit

Androgen Receptor antagonist kit

CL0065 Antifungal compound kit

Antifungal compound kit

CL0046 5-HT Receptor antagonist/agonist kit

5-HT Receptor antagonist/agonist kit

C0050 BCA Protein Quantification Kit

BCA蛋白浓度测定试剂盒

Solution in bottle
CL0110 Progesterone Receptor agonist/antagonist/modulator kit

Progesterone Receptor agonist/antagonist/modulator kit

CL0148 LPL Receptor antagonist/agonist kit

LPL Receptor antagonist/agonist kit

CL0103 mGluR agonist/antagonist/modulator kit

mGluR agonist/antagonist/modulator kit

CL0054 Calcium Channel antagonist/agonist kit

Calcium Channel antagonist/agonist kit

C0066 Human CD34+ Cell Enrichment Kit (positive selection)

人 CD34+ 细胞富集试剂盒 (阴选)

TargetMol 试剂盒

Cell Counting Kit-8 (CCK-8)
Cat.No: C0005
AMPAR antagonist/activator kit
Cat.No: CL0124
Antiparasitic compound kit
Cat.No: CL0050
Wnt/β-catenin/PORCN inhibitor/activator kit
Cat.No: CL0096
TLR agonist/antagonist kit
Cat.No: CL0111
Anti-dsDNA viruses compound kit
Cat.No: CL0086
His-tag 蛋白纯化磁珠 NTA-Ni
Cat.No: C0111
DNA synthesis inhibitor/activator kit
Cat.No: CL0073
Prostaglandin Receptor antagonist/agonist kit
Cat.No: CL0097
Histamine Receptor antagonist kit
Cat.No: CL0049
Anti-HIV compound kit
Cat.No: CL0048
AChR antagonist/agonist kit
Cat.No: CL0047
NMDAR agonist/antagonist kit
Cat.No: CL0104
RNA Synthesis inhibitor/activator kit
Cat.No: CL0090
Endothelin Receptor antagonist kit
Cat.No: CL0144
Adrenergic Receptor antagonist/agonist kit
Cat.No: CL0051
Androgen Receptor antagonist kit
Cat.No: CL0126
Antifungal compound kit
Cat.No: CL0065
5-HT Receptor antagonist/agonist kit
Cat.No: CL0046
BCA蛋白浓度测定试剂盒
Cat.No: C0050
Progesterone Receptor agonist/antagonist/modulator kit
Cat.No: CL0110
LPL Receptor antagonist/agonist kit
Cat.No: CL0148
mGluR agonist/antagonist/modulator kit
Cat.No: CL0103
Calcium Channel antagonist/agonist kit
Cat.No: CL0054
人 CD34+ 细胞富集试剂盒 (阴选)
Cat.No: C0066
Cat. No. Product Name Target Signaling Pathways
T62105 NT219

NT-219

STAT JAK/STAT signaling; Stem Cells
NT219 是一种胰岛素受体底物 1/2 (IRS1/2) 和STAT3的双重抑制剂,可增强错误折叠的朊病毒蛋白的聚集NT219 影响,可提高某些分子伴侣的水平,抑制 STAT3 磷酸化。NT219 具有研究癌症和神经退行性疾病。
T4605 NT157

IGF-1R; STAT JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
NT157 是一种口服生物可利用的间充质-上皮转化 (MET) TKI,主要针对具有 METex14 跳跃突变的特定 NSCLC 患者开发。
TP1023L NT 13 acetate

NT 13 acetate(117928-93-5 free base)

NMDAR Neuroscience
NT 13 acetate 是 NMDA 受体的部分激动剂,可用于抑郁症、焦虑症等相关疾病的研究。
T27178 Dimiracetam

ISF4185,ISF-4185,NT11624,NT-11624,BND11624,BND-11624

Dimiracetam, a NMDA-receptor antagonist, is used potentially for the treatment of neuropathic pain.
TP1023 NT 13

TPPT

NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.
T28215 NT113

NT 113,NT-113

NT113 is a pan-ERBB inhibitor with high brain penetrance. NT113 is active against GBM xenografts in which wild-type EGFR or EGFRvIII is highly expressed. NT113 inhibits the growth of glioblastoma xenografts with EGFR amplification. NT113 has inhibitory ac
T33761 NT2 Purpurin

Purpurin NT 2,NT-2 Purpurin

NT2 Purpurin is used in photodynamic therapy of induced tumors.
T81637 NT-0796

NOD-like Receptor (NLR) Immunology/Inflammation
NT-0796为一种选择性穿透中枢神经系统的NLRP3炎性体抑制剂,其PBMC方法中的IC50值为0.32 nM。该化合物为异丙酯类,能够在细胞内转化为NDT-197959(羧酸活性物)。NT-0796在神经炎症疾病研究中显示出潜力。
T38144 Elinzanetant

Neurokinin receptor GPCR/G Protein; Neuroscience
Elizanetant 是有效的神经激肽受体拮抗剂,在精神分裂症研究中有价值。
T124258 NT 2 Toxin

NT 2 Toxin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124258,CAS号为 76348-84-0。
T38093 NT1-O12B

NT1-O12B

NT1-O12B, an endogenous neurotransmitter-derived lipidoid (NT-lipidoid), serves as a highly efficient carrier for enhancing the transportation of various blood-brain barrier (BBB)-impermeable cargos to the brain. Incorporating NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) enables these LNPs to effectively traverse the BBB. In addition to enabling cargo passage through the BBB, NT-lipidoid formulations facilitate efficient delivery of the cargo into neuronal cells for purposes such as ...
T28296 Parogrelil hydrochloride

INDI-702,NM-702,NT-702,NM702,INDI702

Parogrelil is a phosphodiesterase (PDE3/PDE5A) inhibitor potentially for the treatment of intermittent. Parogrelil suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. Parogrelil improves reduced walking
T78709 NT160

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
NT160,一种IIa类HDAC高效抑制剂,IC50为0.046 μM,适用于中枢神经系统疾病研究。
T19332 Gadopentetic acid

gadolinium complex,钆喷酸,Gd-DTPA

Others Others
Gadopentetic acid (gadolinium complex) 是一种顺磁性造影剂,通常通过静脉内注射 (i.v.) 的方式用于 DCE-MRI 研究。
T18928 Brilliant Black BN

亮黑1,E 151

Others; Virus Protease Microbiology/Virology; Others
Brilliant Black BN (E 151) 是一种偶氮染料和一种食品着色剂。它抑制 EV71 与其细胞脱壳因子亲环蛋白 A 之间的相互作用,是一种很有前途的抗 EV71 感染的抗病毒药物。
T19241 Cloquintocet-mexyl

Others Others
Cloquintocet-mexyl, a herbicide, targets and controls coarse annual grasses within the Poaceae family.
T19058 Solvent Yellow 16

Others Others
Solvent Yellow 16 是化妆品中的着色剂,是一种分散染料。
T10056 Neurokinin antagonist 1

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Neurokinin antagonist 1是一种有效的是神经肽拮抗剂,可用于研究神经系统疾病。
T26637 Antipain dihydrochloride

Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804

Protease Proteases/Proteasome
Antipain dihydrochloride (Antipain 2HCl) 是一种从 Actinomycetes 提取到的蛋白酶抑制剂,具有镇痛活性,抑制 X 射线诱导的人淋巴细胞染色体畸变。
T77582 Anti-inflammatory agent 51

NF-κB NF-κB
Anti-inflammatory agent 51 是一种具有抗炎活性和潜在抗肿瘤活性的酰胺/磺酰胺衍生物,对 NF-κB 激活有抑制作用,可用于研究急性肺损伤和溃疡性结肠炎。
T19059 Solvent Yellow 93

Others Others
Solvent Yellow 93 是偶氮甲胺染料,可用作调色剂的着色剂。
T77780 Zamaporvint

RXC004

Others Others
Zamaporvint (RXC004) 是一种具有选择性、口服活性和有效性的 Wnt 途径抑制剂,作用于膜结合脂肪酰转移酶 Porcupine,阻断 Wnt 配体棕榈酰化、分泌及通路活化。Zamaporvint 在多种癌细胞系中显示出抗肿瘤和抗增殖活性。
T16475 Pexacerfont

BMS-562086

CRFR GPCR/G Protein
Pexacerfont (BMS-562086) 是一种选择性的促肾上腺皮质激素释放因子 (CRF1) 受体拮抗剂,作用于人 CRF1 受体,IC50 为 6.1±0.6 nM。
T31425 Dibenz[a,h]anthracene

CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A

DNA DNA Damage/DNA Repair
Dibenz[a,h]anthracene (CCRIS 208) 诱导细菌DNA 损伤和基因突变,并在几种哺乳动物细胞培养物中诱导基因突变和转化。
T9044 SORT-PGRN interaction inhibitor 1

Neurotensin Receptor GPCR/G Protein
SORT-PGRN interaction inhibitor 1 是一种 sortilin-progranulin 相互作用抑制剂,IC50为 2 μM。
T13114 CCR2 antagonist 4

Teijin compound 1

CCR Immunology/Inflammation; Microbiology/Virology
CCR2 antagonist 4 (Teijin compound 1) 是高效的、特异性的CCR2拮抗剂,对 CCR2b 的IC50为 180 nM,抑制 MCP-1 诱导的趋化作用的 IC50为 24 nM。
T13080L Taranabant

MK-0364

Cannabinoid Receptor GPCR/G Protein
Taranabant (MK-0364) 是一种具有选择性和高效性的 cannabinoid 1 (CB1) 受体反向激动剂,可用于研究肥胖和尼古丁依赖。
T62858 hGPR91 antagonist 3

GPR Endocrinology/Hormones; GPCR/G Protein
hGPR91 antagonist 3 是一种具有口服活性、有效性和选择性的 hGPR91 拮抗剂。hGPR91 antagonist 3 可用于研究高血压、自身免疫性疾病和视网膜血管生成方面的疾病。
T60852 Anticancer agent 46

Anticancer agent 46是一种有效的抗癌剂, 在细胞实验中显示出抗增殖活性,对 MGC803细胞的 IC50为0.986μM。
T38260 SP 600125, negative control

JNK Inhibitor II, negative control

SP 600125, negative control 是 SP 600125 的甲基化类似物,可用作SP 600125的阴性对照,对 DTP3和GADD45β/MKK7(生长停滞和 DNA 损伤诱导型 β/介原活化蛋白激酶激酶 7)具有抑制作用,能够恢复活化。SP 600125, negative control 对 JNK2 和 JNK3 的 IC50s 分别为 18 和 24 μM。
T4569 Lucanthone

Lucantona,Lucanthonum,硫坎酮,硫蒽酮

DNA/RNA Synthesis; Autophagy Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Lucanthone (Lucanthonum) 是一种 Apurinic 核酸内切酶-1 的抑制剂。
T72047 Antibacterial agent 125

Antibacterial Microbiology/Virology
Antibacterial agent 125 是一种抗菌剂。Antibacterial agent 125 对临床相关的革兰氏阳性病原体具有有效的抗菌活性,MIC50值范围为 0.25 - 8 μM。Antibacterial agent 125 可用于抗菌药物耐药性研究。
T1641 Strontium ranelate

Distrontium renelate,S12911,雷尼酸锶

Calcium Channel; CaSR GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
Strontium ranelate (S12911) 是抗骨质疏松的药物,能够抑制骨吸收,促进骨形成,进而促使正骨平衡。它还能够激活非骨骼细胞中的钙敏感受体 (CaSR),进而促进肌醇 1,4,5-三磷酸的生成及丝裂原活化的蛋白激酶信号转导。
T9988 Wnt/β-catenin agonist 3

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Wnt/β-catenin agonist 3是一种Wnt/beta-catenin 信号通路激动剂。
T60803 Wnt/β-catenin agonist 4

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Wnt/β-catenin agonist 4 是一种Wnt的激动剂,可激活Wnt/β-catenin信号,引导信号传输。
T16161 Mutant IDH1 inhibitor

Dehydrogenase; Isocitrate Dehydrogenase (IDH) Metabolism
Mutant IDH1 inhibitor 是一种突变型IDH1 R132H 的抑制剂,IC50<72 nM。
T2675 Bentamapimod

AS 602801

JNK MAPK
Bentamapimod (AS 602801) 是一种ATP 竞争性的JNK 抑制剂,对JNK1、JNK2和JNK3的IC50分别为 80、90 和 230 nM。
T78234 Brilliant Yellow

Direct Yellow 4

transporter Metabolism
Brilliant Yellow (Direct Yellow 4) 是一种具有有效性和选择性的的 VGLUT 抑制剂,是一种染料,可被光降解。
T6101 Entospletinib

GS-9973

Syk Angiogenesis; Tyrosine Kinase/Adaptors
Entospletinib (GS-9973) 是选择性的Syk 抑制剂,其IC50=7.7 nM。
T20720 Norethisterone enanthate

NSC 9564,Norethindrone enanthate,LG-202,LG202,NSC9564,LG 202,炔诺酮庚酸酯,NSC-9564

Estrogen/progestogen Receptor Endocrinology/Hormones
Norethisterone enanthate (NSC-9564) 是一种口服有效的长效的孕激素。
T14133 AEOL-10150 pentachloride

Others Others
AEOL-10150 pentachloride 是一种超氧化物歧化酶模拟物,也是一种金属卟啉催化抗氧剂,可保护肺免受辐射损伤。
T60420 Anticancer agent 73

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Anticancer agent 73 是一种抗癌剂,它能有效地靶向反式激活反应(TAR)RNA 结合蛋白2(TRBP),并破坏TRBP-Dicer 的相互作用。Anticancer agent 73 通过调节 HCC 细胞中 miRNA 组和蛋白质组的表达谱,在体外和体内抑制 HCC 的生长和转移。
T1797 Cabozantinib S-malate

苹果酸卡博替尼,Cabozantinib,卡博替尼苹果酸盐,XL184,Cabozantinib Malate

Apoptosis; VEGFR; c-Met/HGFR; TAM Receptor; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Cabozantinib S-malate (XL184) 是一种多受体酪氨酸激酶抑制剂, 抑制VEGFR2,c-Met,Kit,Axl 和Flt3的IC50分别为0.035,1.3,4.6,7 和 11.3 nM。
T8848 GPR34 receptor antagonist 2

Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-,gpr34-receptor-antagonist-2

Others Others
GPR34 receptor antagonist 2 (Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) 是一种GPR34受体拮抗剂,可用于研究免疫疾病、炎性疾病。
T11230 ERRα antagonist-1

ERR+/- antagonist-1,ERRa antagonist-1

Estrogen/progestogen Receptor Endocrinology/Hormones
ERRα antagonist-1 (ERR+/- antagonist-1) 是一种选择性的,高亲和力的雌激素相关受体α (ERRα) 拮抗剂。ERRα antagonist-1 抑制 ERRα 与增殖物激活的受体γ共激活因子 1α (PGC-1α) 和 PGC-1β 的相互作用,IC50 值分别为 170 nM 和 180 nM。ERRα antagonist-1 不抑制 ERRβ 或 ERRγ 与 PGC-1α 和 PGC-1β 共激活剂的相互作用,也不抑制 ERα 或 ERβ 与 PGC-1α 或 SRC-1 的相互作用。
T27122 Dasantafil

SCH446132,SCH-446132,SCH 446132

PDE Metabolism
Dasantafil (SCH446132) 是一种小分子磷酸二酯酶-5A(PDE5A)抑制剂,可用于治疗泌尿生殖系统疾病和研究勃起功能障碍。
T10269 AHR antagonist 2

Aryl Hydrocarbon Receptor Immunology/Inflammation
AHR antagonist 2 是芳基烃受体的拮抗剂。 人 AHR 和小鼠 AHR 的 IC50 分别为 0.885 和 2.03 nM。
T8333 Aurintricarboxylic acid

ATA,NSC-4056,NSC4056,金精三羧酸,NSC 4056

Apoptosis; P2X Receptor; Influenza Virus; Topoisomerase Apoptosis; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Aurintricarboxylic acid (NSC-4056) 是高效的αβ-亚甲基-ATP 敏感选择性P2X1Rs 和P2X3Rs 变构拮抗剂。 它是核糖核酸酶和拓扑异构酶 II 的有效抑制剂,可阻止核酸与酶结合。
T66121 Ketoconazole Intermediate 1e

(cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate

Others Others
Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate) 是一种酮康唑中间体。
T11237L Camizestrant TFA

Camizestrant TFA(2222844-89-3 Free base),AZD-9833 TFA

Estrogen Receptor/ERR Endocrinology/Hormones
Camizestrant TFA (AZD-9833 TFA) 是一种有效的口服雌激素受体拮抗剂。

化合物

NT219
Cat.No: T62105
Synonym: NT-219
Target: STAT
NT157
Cat.No: T4605
Synonym:
Target: IGF-1R, STAT
NT 13 acetate
Cat.No: TP1023L
Synonym: NT 13 acetate(117928-93-5 free base)
Target: NMDAR
Dimiracetam
Cat.No: T27178
Synonym: ISF4185,ISF-4185,NT11624,NT-11624,BND11624,BND-11624
Target:
NT 13
Cat.No: TP1023
Synonym: TPPT
Target:
NT113
Cat.No: T28215
Synonym: NT 113,NT-113
Target:
NT2 Purpurin
Cat.No: T33761
Synonym: Purpurin NT 2,NT-2 Purpurin
Target:
NT-0796
Cat.No: T81637
Synonym:
Target: NOD-like Receptor (NLR)
Elinzanetant
Cat.No: T38144
Synonym:
Target: Neurokinin receptor
NT 2 Toxin
Cat.No: T124258
Synonym:
Target:
NT1-O12B
Cat.No: T38093
Synonym: NT1-O12B
Target:
Parogrelil hydrochloride
Cat.No: T28296
Synonym: INDI-702,NM-702,NT-702,NM702,INDI702
Target:
NT160
Cat.No: T78709
Synonym:
Target: HDAC
Gadopentetic acid
Cat.No: T19332
Synonym: gadolinium complex,钆喷酸,Gd-DTPA
Target: Others
Brilliant Black BN
Cat.No: T18928
Synonym: 亮黑1,E 151
Target: Others, Virus Protease
Cloquintocet-mexyl
Cat.No: T19241
Synonym:
Target: Others
Solvent Yellow 16
Cat.No: T19058
Synonym:
Target: Others
Neurokinin antagonist 1
Cat.No: T10056
Synonym:
Target: Neuropeptide Y Receptor
Antipain dihydrochloride
Cat.No: T26637
Synonym: Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804
Target: Protease
Anti-inflammatory agent 51
Cat.No: T77582
Synonym:
Target: NF-κB
Solvent Yellow 93
Cat.No: T19059
Synonym:
Target: Others
Zamaporvint
Cat.No: T77780
Synonym: RXC004
Target: Others
Pexacerfont
Cat.No: T16475
Synonym: BMS-562086
Target: CRFR
Dibenz[a,h]anthracene
Cat.No: T31425
Synonym: CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A
Target: DNA
SORT-PGRN interaction inhibitor 1
Cat.No: T9044
Synonym:
Target: Neurotensin Receptor
CCR2 antagonist 4
Cat.No: T13114
Synonym: Teijin compound 1
Target: CCR
Taranabant
Cat.No: T13080L
Synonym: MK-0364
Target: Cannabinoid Receptor
hGPR91 antagonist 3
Cat.No: T62858
Synonym:
Target: GPR
Anticancer agent 46
Cat.No: T60852
Synonym:
Target:
SP 600125, negative control
Cat.No: T38260
Synonym: JNK Inhibitor II, negative control
Target:
Lucanthone
Cat.No: T4569
Synonym: Lucantona,Lucanthonum,硫坎酮,硫蒽酮
Target: DNA/RNA Synthesis, Autophagy
Antibacterial agent 125
Cat.No: T72047
Synonym:
Target: Antibacterial
Strontium ranelate
Cat.No: T1641
Synonym: Distrontium renelate,S12911,雷尼酸锶
Target: Calcium Channel, CaSR
Wnt/β-catenin agonist 3
Cat.No: T9988
Synonym:
Target: Wnt/beta-catenin
Wnt/β-catenin agonist 4
Cat.No: T60803
Synonym:
Target: Wnt/beta-catenin
Mutant IDH1 inhibitor
Cat.No: T16161
Synonym:
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
Bentamapimod
Cat.No: T2675
Synonym: AS 602801
Target: JNK
Brilliant Yellow
Cat.No: T78234
Synonym: Direct Yellow 4
Target: transporter
Entospletinib
Cat.No: T6101
Synonym: GS-9973
Target: Syk
Norethisterone enanthate
Cat.No: T20720
Synonym: NSC 9564,Norethindrone enanthate,LG-202,LG202,NSC9564,LG 202,炔诺酮庚酸酯,NSC-9564
Target: Estrogen/progestogen Receptor
AEOL-10150 pentachloride
Cat.No: T14133
Synonym:
Target: Others
Anticancer agent 73
Cat.No: T60420
Synonym:
Target: DNA/RNA Synthesis
Cabozantinib S-malate
Cat.No: T1797
Synonym: 苹果酸卡博替尼,Cabozantinib,卡博替尼苹果酸盐,XL184,Cabozantinib Malate
Target: Apoptosis, VEGFR, c-Met/HGFR, TAM Receptor, c-Kit
GPR34 receptor antagonist 2
Cat.No: T8848
Synonym: Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-,gpr34-receptor-antagonist-2
Target: Others
ERRα antagonist-1
Cat.No: T11230
Synonym: ERR+/- antagonist-1,ERRa antagonist-1
Target: Estrogen/progestogen Receptor
Dasantafil
Cat.No: T27122
Synonym: SCH446132,SCH-446132,SCH 446132
Target: PDE
AHR antagonist 2
Cat.No: T10269
Synonym:
Target: Aryl Hydrocarbon Receptor
Aurintricarboxylic acid
Cat.No: T8333
Synonym: ATA,NSC-4056,NSC4056,金精三羧酸,NSC 4056
Target: Apoptosis, P2X Receptor, Influenza Virus, Topoisomerase
Ketoconazole Intermediate 1e
Cat.No: T66121
Synonym: (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate
Target: Others
Camizestrant TFA
Cat.No: T11237L
Synonym: Camizestrant TFA(2222844-89-3 Free base),AZD-9833 TFA
Target: Estrogen Receptor/ERR
Cat. No. Product Name Target Signaling Pathways
T5656 (±)-Norcantharidin

Endothall anhydride,去甲斑蝥素,Norcantharidin

EGFR; c-Met/HGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
(±)-Norcantharidin (Endothall anhydride) 是一种人类结肠癌中 c-Met 和 EGFR 的双重抑制剂,可研究抗癌,具有抗血管生成活性。
T3858 macranthoidin A

灰毡毛忍冬皂苷甲,金银花

Others Others
Macranthoidin A 是一种具有口服活性的、提取于金银花中的皂苷。它对四氯化碳,对乙酰氨基酚和镉所致的肝损伤具有保护作用,对耳巴豆油的溶胀具有明显的抑制作用。
TN1079 Deoxyelephantopin

NF-κB NF-κB
Deoxyelephantopin 是来自Elephantopus scaber 的,具有生物活性的天然倍半萜烯内酯,能够抑制NF-κB,MAPK,PI3K/Akt 和β-catenin 信号传导。它可广泛用于癌症方面的研究。
T5S2205 Sibiricaxanthone B

Others Others
Sibiricaxanthone B 是一种氧杂蒽酮,分离自远志。
T3S1641 Esculentoside H

TNF; NF-κB; JNK Apoptosis; MAPK; NF-κB
Esculentoside H 是一种皂苷,分离自多年生植物 Phytolacca esculent 的根提取物中,具有抗肿瘤作用。它的机制与 TNF 释放能力有关。它能够阻断 JNK1/2和 NF-κB 信号介导的基质金属蛋白酶-9 (MMP-9) 表达,抑制结肠癌细胞迁移。
T3718 Santonin

驱蛔蒿,α-santonin,alpha-Santonin,山道年,Semenen

Others; Parasite Microbiology/Virology; Others
Santonin (alpha-Santonin) 是Artemisia cina 的活性成分,可用于研究蠕虫感染。它是一种有效的抗寄生虫剂。
T8052 (E)-2-Methyl-2-pentenoic acid

trans-2-Methyl-2-pentenoic Acid,反式-2-甲基-2-戊烯酸

Others Others
(E)-2-Methyl-2-pentenoic acid 可作为合成具有细胞毒性的天然产物 Lactimidomycin 的组分。
T5704 Entadamide-A-β-D-glucopyranoside

(E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-,榼藤子酰胺A-Β-D-吡喃葡萄糖苷,榼藤子酰胺A-β-D-吡喃葡萄糖

Others Others
Entadamide-A-β-D-glucopyranoside ((E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-) 是一种菜豆虫种子的主要成分,具有抗补体作用。
TN2316 Xanthyletin

花椒树皮素甲,美洲花椒素

MMP; ERK; Antifungal MAPK; Microbiology/Virology; Proteases/Proteasome
Xanthyletin 是从 Citrus 中得到的香豆素类化合物,具有抗炎、抗肿瘤和抗菌活性,还抑制切叶蚁培育的共生真菌。
TN7249 Nor-rubrofusarin gentiobioside

Nor-rubrofusarin gentiobioside 是从豆科植物决明子中发现的天然产物。
TN4451 Lophanthoidin B

Others Others
Lophanthoidin B 是一种二萜类化合物,提取自从Rabdosia lophanthoides 的干叶。
TN4453 Lophanthoidin F

Others Others
Lophanthoidin F 是一种二萜化合物,提取自Rabdosia lophanthoides 的干叶。
TN7021 Ent-toddalolactone

Others Others
Ent-toddalolactone 是一种天然化合物,属于香豆素类,来源于两面针,具有抗炎、抗癌活性。
TJS2216 Aurantiamide acetate

金色酰胺醇酯,Asperglaucide

Cysteine Protease Proteases/Proteasome
Aurantiamide acetate (Asperglaucide) 是抑制口服有活性的 cathepsin 选择性抑制剂,分离自 Portulaca oleracea L。它具有抗炎作用,可用于研究炎性相关疾病。
TN2165 Rubrofusarin gentiobioside

Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷

ERK; NF-κB; TGF-beta/Smad MAPK; NF-κB; Stem Cells
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) 一种分离自决明子的、具有清除自由基作用的化合物。
TN6740 Emodinanthrone

大黄素蒽酮,Emodin anthranol,Emodin anthrone,emodinol

Others; Antibiotic Microbiology/Virology; Others
Emodinanthrone 是一种蒽醌类化合物,是大黄素的前体,具有抗生素活性。它抑制大肠杆菌膜囊泡中呼吸驱动的溶质转运。
TN4660 Niranthin

Anti-infection; HBV; PAFR; Topoisomerase DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology
Niranthin 是一种木脂素,具有广泛的药理活性。它是L. donovaniIB 拓扑异构酶的非竞争性抑制剂,可用于研究耐药利什曼病的治疗。
T0086 Galanthamine hydrobromide

Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏

AChR; AChE Neuroscience
Galanthamine hydrobromide (Galantamine hydrobromide) 是一种长效的中枢活性 AChE 抑制剂,IC50为 410 nM。它是神经元烟碱型 ACh 受体的变构增强剂,IC50值为 0.35 µM,可用于阿尔茨海默症的研究。
T8202 Kaempferol 3-O-gentiobioside

Kaempferol 3-gentiobioside,山柰酚 3-龙胆双糖苷

Glucosidase Metabolism
Kaempferol 3-O-gentiobioside 是一种黄酮类化合物,从C. alata 叶中分离得到,具有抗糖尿病特性。它有抗 α-glucosidase 活性,并具有对碳水化合物酶的抑制作用,其 IC50=50.0 µM。
T0925 Allantoin

Glyoxyldiureide,尿囊素,5-Ureidohydantoin

Endogenous Metabolite; Imidazoline Receptor Metabolism; Neuroscience
Allantoin (Glyoxyldiureide) 是一种存在于尿液和植物中的尿素乙内酰脲,用于皮肤病制剂。
T7068 Eicosapentaenoic acid ethyl ester

Icosapent ethyl,顺-二十碳五烯酸乙酯,EPA ethyl ester,Ethyl eicosapentaenoate

Others; Endogenous Metabolite Metabolism; Others
Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) 是 一种ω-3 脂肪酸剂和人内源性代谢物。
T5071 4-Methyl-2-oxopentanoic acid

4-甲基-2-氧代戊酸,4-Methyl-2-oxovaleric acid

Others; Endogenous Metabolite Metabolism; Others
4-Methyl-2-oxopentanoic acid (4-Methyl-2-oxovaleric acid) 是一种非正常代谢物,是一种神经毒素和代谢毒素。
T8058 2-Methyl-4-pentenoic Acid

2-甲基-4-戊酸,2-Methylpent-4-enoic acid

Others Others
2-Methyl-4-pentenoic Acid (2-Methylpent-4-enoic acid) 是一种有机酸。
TMO2681 Xanthosine

9-Beta-D-Ribofuranosylxanthine,黄嘌呤核苷,Xanthine riboside

Others; Endogenous Metabolite Metabolism; Others
Xanthosine (9-Beta-D-Ribofuranosylxanthine) 是黄嘌呤核苷,它能够提高山羊和牛的乳腺干细胞数量和产奶量。
T4S1659 Xanthotoxol

8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,花椒毒酚,8-Hydroxypsoralene

Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Xanthotoxol (Psoralen) 是一种具有生物活性的线性呋喃香豆素,具有很强的抗炎、抗氧化、5-HT 拮抗和神经保护作用等药理活性。
T7600 Fucoxanthin

all-trans-Fucoxanthin

Others Others
Fucoxanthin (all-trans-Fucoxanthin) 是海洋类胡萝卜素,具有抗肥胖,抗糖尿病,抗炎,抗氧化,抗癌等作用。
T3877 Esculentoside A

NF-κB; COX Immunology/Inflammation; Neuroscience; NF-κB
Esculentoside A 是一种三萜皂苷,从商陆根部分离得到。它在具有抗炎活性,对环氧合酶-2 具有选择性抑制活性。它通过抑制NF-κB 和丝裂原活化蛋白激酶信号通路抑制 LPS 诱导的急性肺损伤中的炎症反应。
T20225 Dicentrine, (-)-

L-Dicentrine,荷包牡丹碱,NSC 251699,NSC251699,NSC-251699

Others Others
Dicentrine, (-)- (NSC-251699) 是一种在几种植物物种中发现的非卟啉生物碱,在小鼠内脏痛的急性模型中显示出显著的镇痛活性。
TN1084 1,3,5,8-Tetrahydroxyxanthone

Desmethylbellidifolin,去甲基雏叶龙胆酮

Anti-infection Microbiology/Virology
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) 是一种天然黄酮,从 Gentianella acuta 中提取得到。它具有镇痉作用和抗炎作用。
T8109 d-Neomenthol

(1S,2S,5R)-2-Isopropyl-5-Methylcyclohexanol,(1S,2S,5R)-(+)-新薄荷醇,(+)-Neomenthol

Others Others
d-Neomenthol ((+)-Neomenthol) 是一种天然产物。
TN1141 Isodeoxyelephantopin

异去氧苦地胆素,异去氧苦地胆苦素

NF-κB; Reactive Oxygen Species; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
Isodeoxyelephantopin 是从地胆草中分离得到的一种倍半萜烯内酯,能调节 LncRNA 的表达,有抗乳腺癌的作用。它可诱导活性氧的生成,抑制 NF-κB 的激活。
T19138 4-Methylpentanoic acid

4-甲基戊酸,Isocaproic Acid

Others Others
4-Methylpentanoic acid (Isocaproic Acid) 是一种短链脂肪酸 (SCFA).
T5569 3-Amino-4-methylpentanoic acid

DL-Homovaline,3-氨基-4-甲基戊酸,DL-beta-leucine,beta-Aminoisocaproic acid,beta-Leucine

Endogenous Metabolite Metabolism
3-Amino-4-methylpentanoic acid (DL-Homovaline) 是 L-亮氨酸的异构体,是 β 氨基酸,通过亮氨酸 2,3-氨基变位酶在人体中由 L-亮氨酸代谢天然产生。
T7978 Cyclopentadecanone

Others Others
Cyclopentadecanone 用于香水(麝香气味)。
T2976 (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one

Sorbinose,L-山梨糖,Sorbin,Esorben,L(-)-sorbose,L(-)-Sorbopyranose

Others; Endogenous Metabolite Metabolism; Others
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one (L(-)-Sorbopyranose) 是内源性代谢产物的一种。
TMO2787 Anthraquinone

dioxoanthracene,Anthradione,anthracenedione,蒽醌

Virus Protease Microbiology/Virology
Anthraquinone (Anthradione) 是常用于缓解便秘的草药中的主要活性成分,可用作染料形成前体。
T13354 Xanthoangelol

Apoptosis; Monoamine Transporter; Antibacterial; AMPK Apoptosis; Chromatin/Epigenetic; Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling
Xanthoangelol 可从 Angelica keiskei 中提取得到,对肥胖引起的炎症反应有抑制作用。Xanthoangelol 具有抗菌活性,对单胺氧化酶有抑制作用,还诱导神经母细胞瘤和白血病细胞凋亡。
T5222 N-(5-Aminopentyl)acetamide

Monoacetylcadaverine,N-(5-氨基戊基)乙酰胺,N-Acetylcadaverine,N-Acetyl-1,5-pentanediamine

Others; Endogenous Metabolite Metabolism; Others
N-(5-Aminopentyl)acetamide (N-Acetylcadaverine) 是用作多胺尸胺的乙酰化形式。尸胺是有机体中的氨基酸分解产生的,大剂量时有毒。
T2S0663 Humantenmine

P450 Metabolism
Humantenmine 是一种分离自中国线虫中的生物碱,有用于疼痛和风湿性关节炎的研究潜力。
TN1892 Lusianthridin

Others; c-Myc Cell Cycle/Checkpoint; Others
Lusianthridin 是来自石斛 Dendrobium venustum 的天然产物。 Lusianthridin 在无毒浓度下表现出抗迁移特性。 Lusianthridin 通过抑制 Src-STAT3 信号传导增强 c-Myc 降解。
TQ0213 Bruceantin

鸦胆亭,(-)-Bruceantin,NCI165563,鸦胆停,NSC165563

Others Others
Bruceantin (NSC-165563) 提取自痢鸦胆子中,显示出对 B16黑色素瘤,结肠癌38,L1210和白血病 P388的抑制活性。
T4895 Pentane-1,5-diamine dihydrochloride

5-diamine dihydrochloride,Cadaverine dihydrochloride,1,5-戊二胺盐酸盐,Pentane-1

Endogenous Metabolite Metabolism
Pentane-1,5-diamine dihydrochloride (Cadaverine dihydrochloride) 是内源性代谢产物的一种。
TJP2891 Maltopentaose

麦芽五糖,Maltopentose

Others; Endogenous Metabolite Metabolism; Others
Maltopentaose (Maltopentose) 是一种麦芽糊精中的低聚糖,能够用于 α-乳清蛋白的糖化和磷酸化的研究。
T6S1559 Aurantio-obtusin

Others Others
Aurantio-obtusin 是从决明子中分离出的蒽醌类化合物,具有抗炎、抗凝血、抗氧化、抗高血压的活性。它能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应,具有研究过敏相关疾病的潜力。在大鼠中,它通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉,是潜在的新型血管扩张剂。
T13741 Isoviolanthin

异佛莱心苷,异佛来心苷

Others Others
Isoviolanthin 是一种黄酮类苷类化合物,提取自铁皮石斛叶中。它能减少 TGF-β1 处理的 HCC 细胞的迁移和入侵能力,对正常细胞没有毒性影响,对转移性肝癌晚期具有潜在的研究价值。
T4S1439 6'-O-beta-D-Glucosylgentiopicroside

6'-O-β-D-葡萄糖基龙胆苦苷,6'-O-Glucosylgentiopicroside

Antifungal Microbiology/Virology
6'-O-beta-D-Glucosylgentiopicroside (6'-O-Glucosylgentiopicroside) 是一种环烯醚萜,分离自G. straminea 根中。它能显著抑制 fMLP 诱导的超氧化物生成。
T14008 2,2,5,7,8-Pentamethyl-6-Chromanol

PMC

Androgen Receptor Endocrinology/Hormones
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) 是维生素 E (α-tocopherol) 的抗氧化部分,能够有效的调节雄激素受体 (androgen receptor) 信号,及抗前列腺癌细胞系的抗癌活性。
T4601 9-Methoxycanthin-6-one

Others Others
9-Methoxycanthin-6-one 是存在于完整植株和不同外植体的愈伤组织中的 Canthin-6-one 生物碱,具有抗肿瘤作用。
T8111 Triacontanoic Acid

蜂花酸,Melissic acid A

Others Others
Triacontanoic Acid (Melissic acid A) 是一种超长链脂肪酸。
TJS0387 Desoxyrhaponticin

去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin

Apoptosis; Fatty Acid Synthase Apoptosis; Metabolism
Desoxyrhaponticin (Deoxyrhaponticin) 是来自西藏营养食品唐古特大黄中的一种二苯乙烯苷。它是脂肪酸合成酶抑制剂,抑制细胞内 FAS 活性,下调人乳腺癌 MCF-7细胞中 FAS 的表达。它是控制糖尿病餐后高血糖的潜在药物。
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天然产物

(±)-Norcantharidin
Cat.No: T5656
Synonym: Endothall anhydride,去甲斑蝥素,Norcantharidin
Target: EGFR, c-Met/HGFR
macranthoidin A
Cat.No: T3858
Synonym: 灰毡毛忍冬皂苷甲,金银花
Target: Others
Deoxyelephantopin
Cat.No: TN1079
Synonym:
Target: NF-κB
Sibiricaxanthone B
Cat.No: T5S2205
Synonym:
Target: Others
Esculentoside H
Cat.No: T3S1641
Synonym:
Target: TNF, NF-κB, JNK
Santonin
Cat.No: T3718
Synonym: 驱蛔蒿,α-santonin,alpha-Santonin,山道年,Semenen
Target: Others, Parasite
(E)-2-Methyl-2-pentenoic acid
Cat.No: T8052
Synonym: trans-2-Methyl-2-pentenoic Acid,反式-2-甲基-2-戊烯酸
Target: Others
Entadamide-A-β-D-glucopyranoside
Cat.No: T5704
Synonym: (E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-,榼藤子酰胺A-Β-D-吡喃葡萄糖苷,榼藤子酰胺A-β-D-吡喃葡萄糖
Target: Others
Xanthyletin
Cat.No: TN2316
Synonym: 花椒树皮素甲,美洲花椒素
Target: MMP, ERK, Antifungal
Nor-rubrofusarin gentiobioside
Cat.No: TN7249
Synonym:
Target:
Lophanthoidin B
Cat.No: TN4451
Synonym:
Target: Others
Lophanthoidin F
Cat.No: TN4453
Synonym:
Target: Others
Ent-toddalolactone
Cat.No: TN7021
Synonym:
Target: Others
Aurantiamide acetate
Cat.No: TJS2216
Synonym: 金色酰胺醇酯,Asperglaucide
Target: Cysteine Protease
Rubrofusarin gentiobioside
Cat.No: TN2165
Synonym: Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷
Target: ERK, NF-κB, TGF-beta/Smad
Emodinanthrone
Cat.No: TN6740
Synonym: 大黄素蒽酮,Emodin anthranol,Emodin anthrone,emodinol
Target: Others, Antibiotic
Niranthin
Cat.No: TN4660
Synonym:
Target: Anti-infection, HBV, PAFR, Topoisomerase
Galanthamine hydrobromide
Cat.No: T0086
Synonym: Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏
Target: AChR, AChE
Kaempferol 3-O-gentiobioside
Cat.No: T8202
Synonym: Kaempferol 3-gentiobioside,山柰酚 3-龙胆双糖苷
Target: Glucosidase
Allantoin
Cat.No: T0925
Synonym: Glyoxyldiureide,尿囊素,5-Ureidohydantoin
Target: Endogenous Metabolite, Imidazoline Receptor
Eicosapentaenoic acid ethyl ester
Cat.No: T7068
Synonym: Icosapent ethyl,顺-二十碳五烯酸乙酯,EPA ethyl ester,Ethyl eicosapentaenoate
Target: Others, Endogenous Metabolite
4-Methyl-2-oxopentanoic acid
Cat.No: T5071
Synonym: 4-甲基-2-氧代戊酸,4-Methyl-2-oxovaleric acid
Target: Others, Endogenous Metabolite
2-Methyl-4-pentenoic Acid
Cat.No: T8058
Synonym: 2-甲基-4-戊酸,2-Methylpent-4-enoic acid
Target: Others
Xanthosine
Cat.No: TMO2681
Synonym: 9-Beta-D-Ribofuranosylxanthine,黄嘌呤核苷,Xanthine riboside
Target: Others, Endogenous Metabolite
Xanthotoxol
Cat.No: T4S1659
Synonym: 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,花椒毒酚,8-Hydroxypsoralene
Target: Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite
Fucoxanthin
Cat.No: T7600
Synonym: all-trans-Fucoxanthin
Target: Others
Esculentoside A
Cat.No: T3877
Synonym:
Target: NF-κB, COX
Dicentrine, (-)-
Cat.No: T20225
Synonym: L-Dicentrine,荷包牡丹碱,NSC 251699,NSC251699,NSC-251699
Target: Others
1,3,5,8-Tetrahydroxyxanthone
Cat.No: TN1084
Synonym: Desmethylbellidifolin,去甲基雏叶龙胆酮
Target: Anti-infection
d-Neomenthol
Cat.No: T8109
Synonym: (1S,2S,5R)-2-Isopropyl-5-Methylcyclohexanol,(1S,2S,5R)-(+)-新薄荷醇,(+)-Neomenthol
Target: Others
Isodeoxyelephantopin
Cat.No: TN1141
Synonym: 异去氧苦地胆素,异去氧苦地胆苦素
Target: NF-κB, Reactive Oxygen Species, Autophagy
4-Methylpentanoic acid
Cat.No: T19138
Synonym: 4-甲基戊酸,Isocaproic Acid
Target: Others
3-Amino-4-methylpentanoic acid
Cat.No: T5569
Synonym: DL-Homovaline,3-氨基-4-甲基戊酸,DL-beta-leucine,beta-Aminoisocaproic acid,beta-Leucine
Target: Endogenous Metabolite
Cyclopentadecanone
Cat.No: T7978
Synonym:
Target: Others
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one
Cat.No: T2976
Synonym: Sorbinose,L-山梨糖,Sorbin,Esorben,L(-)-sorbose,L(-)-Sorbopyranose
Target: Others, Endogenous Metabolite
Anthraquinone
Cat.No: TMO2787
Synonym: dioxoanthracene,Anthradione,anthracenedione,蒽醌
Target: Virus Protease
Xanthoangelol
Cat.No: T13354
Synonym:
Target: Apoptosis, Monoamine Transporter, Antibacterial, AMPK
N-(5-Aminopentyl)acetamide
Cat.No: T5222
Synonym: Monoacetylcadaverine,N-(5-氨基戊基)乙酰胺,N-Acetylcadaverine,N-Acetyl-1,5-pentanediamine
Target: Others, Endogenous Metabolite
Humantenmine
Cat.No: T2S0663
Synonym:
Target: P450
Lusianthridin
Cat.No: TN1892
Synonym:
Target: Others, c-Myc
Bruceantin
Cat.No: TQ0213
Synonym: 鸦胆亭,(-)-Bruceantin,NCI165563,鸦胆停,NSC165563
Target: Others
Pentane-1,5-diamine dihydrochloride
Cat.No: T4895
Synonym: 5-diamine dihydrochloride,Cadaverine dihydrochloride,1,5-戊二胺盐酸盐,Pentane-1
Target: Endogenous Metabolite
Maltopentaose
Cat.No: TJP2891
Synonym: 麦芽五糖,Maltopentose
Target: Others, Endogenous Metabolite
Aurantio-obtusin
Cat.No: T6S1559
Synonym:
Target: Others
Isoviolanthin
Cat.No: T13741
Synonym: 异佛莱心苷,异佛来心苷
Target: Others
6'-O-beta-D-Glucosylgentiopicroside
Cat.No: T4S1439
Synonym: 6'-O-β-D-葡萄糖基龙胆苦苷,6'-O-Glucosylgentiopicroside
Target: Antifungal
2,2,5,7,8-Pentamethyl-6-Chromanol
Cat.No: T14008
Synonym: PMC
Target: Androgen Receptor
9-Methoxycanthin-6-one
Cat.No: T4601
Synonym:
Target: Others
Triacontanoic Acid
Cat.No: T8111
Synonym: 蜂花酸,Melissic acid A
Target: Others
Desoxyrhaponticin
Cat.No: TJS0387
Synonym: 去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin
Target: Apoptosis, Fatty Acid Synthase
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Cat. No. Product Name Species Expression System
TMPY-05804 NT-4 Protein, Human, Recombinant

GLC10,NT-4/5,NT4,GLC1O,NT-5,N...

Human E. coli
NT-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.93 kDa and the accession number is A0A024QZE4.
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant

NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3

Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPY-01851 CD73 Protein, Human, Recombinant (His)

eN,NT5,E5NT,NT,5'-nucleotidase, e...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-01342 CD73 Protein, Mouse, Recombinant (His)

CD73,AI447961,2210401F01Rik,NT,5'-nucleotidase, ect...

Mouse HEK293 Cells
CD73 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is Q0VEE0.
TMPY-00561 Neurotensin Protein, Human, Recombinant (hFc)

NMN-125,NTS1,NN,NT/N,neurotensin,NT

Human HEK293 Cells
NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs to the neurotensin family. NTS is an endogenous tridecapeptide of the central nervous system and the gastrointestinal tract of different mammalian species including the human. The human gene encoding neurotensin has previously been assigned to chromosome 12 but no regional locali...
TMPK-00982 NTS1 Protein, Cynomolgus, Recombinant (His)

NTR1,NT,NTRR,NTRH,NT...

Cynomolgus HEK293 Cells
Crystal structures of neurotensin receptor subtype 1 (NTS1) allowed us to visualize the binding mode of the endogenous peptide hormone neurotensin and its pharmacologically active C-terminal fragment NT(8-13) within the orthosteric binding pocket of NTS1. NTS1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 18.84 kDa and the accession number is Q2PG57.
TMPK-01162 NTS1 Protein, Mouse, Recombinant (hFc)

NTS1,NTRH,NN,NT,NTR1,NMN...

Mouse HEK293 Cells
Crystal structures of neurotensin receptor subtype 1 (NTS1) allowed us to visualize the binding mode of the endogenous peptide hormone neurotensin and its pharmacologically active C-terminal fragment NT(8-13) within the orthosteric binding pocket of NTS1. NTS1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9D3P9.
TMPY-06907 CD73 Protein, Human, Recombinant (His & Avi), Biotinylated

E5NT,NTE,CD73,NT5,5'-nucleotidase...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 61.04 kDa and the accession number is NP_002517.1.
TMPY-05580 CD73 Protein, Human, Recombinant (hFc)

NT,CALJA,5'-nucleotidase, ecto (CD73),eN,eNT

Human HEK293 Cells
CD73 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is P21589-1.
TMPY-02155 Prostatic Acid Phosphatase Protein, Human, Recombinant (His)

5'-NT,acid phosphatase, prostate,PAP,ACP-3,ACP3

Human HEK293 Cells
Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2.
TMPY-05454 CD73 Protein, Human, Recombinant (His), Biotinylated

E5NT,eN,NT,NT5,5'-nucleotidase, e...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPJ-00874 NT-proBNP Protein, Human, Recombinant (His & Flag)

γ-brain natriuretic peptide,Gamma-brain natriuretic peptide,...

Human E. coli
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such ...
TMPY-02672 Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)

5'-NT,9.104100899-104272570.1,Ppal,A030005E02Rik,PA...

Mouse HEK293 Cells
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1.
TMPJ-00514 ACPP Protein, Human, Recombinant (His)

Ecto-5'-Nucleotidase,TMPase,5'-Nucleotidase,Thiamine Monopho...

Human HEK293 Cells
Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6; its activity can be inhibited by L(+)-tartrate.
TMPJ-00489 NTAQ1 Protein, Human, Recombinant (GST)

Nt(Q)-amidase,C8orf32,NTAQ1,Protein NH2-te...

Human E. coli
Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it do...
TMPY-02893 NT5C3A/NT5C3 Protein, Human, Recombinant

P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,...

Human E. coli
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPJ-01092 MGAT2 Protein, Human, Recombinant (His)

Alpha-1,Mannoside Acetylglucosaminyltransferase 2,6-Mannosyl...

Human HEK293 Cells
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
TMPH-00858 NT5C Protein, Human, Recombinant (His & Myc)

Human E. coli
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. NT5C Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.4 kDa and the accession number is Q8TCD5.
TMPH-01197 NT5C1A Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
NT5C1A Protein, Human, Recombinant (His) is expressed in Yeast.
TMPJ-01469 NGF Protein, Human, Recombinant (E. colli)

NGFB,神经生长因子,β-NGF,NGF,Beta-Nerve Growth Factor,β-Nerve Growt...

Mouse E. coli
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an impo...
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant

BDNF,Abrineurin,Brain-Derived Neurotrophic Factor

Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ...
TMPY-03104 FGF-17 Protein, Human, Recombinant

fibroblast growth factor 17,HH20,FGF-13,FGF-17

Human E. coli
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling mol...
TMPY-02801 PHGDH Protein, Human, Recombinant (His)

phosphoglycerate dehydrogenase,HEL-S-113,3PGDH,NLS1,PHGDHD,P...

Human E. coli
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for site-directed mutagenesis. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. PH...
TMPY-03958 TGF alpha Protein, Human, Recombinant

transforming growth factor α,转化生长因子,transforming growth fact...

Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (...
TMPY-02219 Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

NS1 Protein

H1N1 E. coli
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPY-02521 HIST3H2A Protein, Human, Recombinant

histone cluster 3, H2a,MGC3165

Human E. coli
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,...
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain)

HME,ME,MMP-12,MME,matrix metallopeptidase 12

Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPY-02062 SULT1A1 Protein, Human, Recombinant (His)

HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotransferase family, cyt...

Human E. coli
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa...
TMPY-00105 Recombinant Protein G

E. coli
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig...
TMPY-00005 FGF-8a Protein, Human, Recombinant

fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-06983 IFN gamma Protein, Human, Recombinant (E. coli)

Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干扰素,In...

Human E. coli
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ...
TMPY-03195 Serum Amyloid P Protein, Human, Recombinant (His)

amyloid P component, serum,HEL-S-92n,SAP,PTX2

Human HEK293 Cells
Serum Amyloid P Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P02743.
TMPY-03203 CD40 Protein, Rat, Recombinant (His)

CD40 molecule, TNF receptor superfamily member 5

Rat HEK293 Cells
CD40 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.6 kDa and the accession number is A0A8I6A2T5.
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi)

tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,tβR-I,TGF-...

Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
TMPK-00785 ANXA2 Protein, Mouse, Recombinant (His)

LIP2PAP-IV,Annexin II,LPC2DP36,LPC2D,CAL1H,Annexin A2,ANX2L4...

Mouse E. coli
ANXA2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 39.6 kDa and the accession number is P07356.
TMPY-01864 CNTF Protein, Human, Recombinant (His)

ciliary neurotrophic factor,HCNTF

Human E. coli
CNTF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.5 kDa and the accession number is P26441.
TMPY-01802 c-Kit Protein, Mouse, Recombinant (His)

SCO5,SCO1,Bs,Gsfsco1,v-kit Hardy-Zuckerman 4 feline sarcoma ...

Mouse HEK293 Cells
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P05532-1.
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

Flt-4,VEGFR-3,Chy,fms related tyrosine kinase 4,VEGFR3,AI323...

Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1.
TMPY-01807 NKp44/NCR2 Protein, Human, Recombinant (His)

RP1-149M18.2,LY95,dJ149M18.1,NK-p44,CD336,natural cytotoxici...

Human HEK293 Cells
NKp44/NCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is O95944-1.
TMPY-01262 TROP-2 Protein, Human, Recombinant (His)

TROP2,M1S1,GA733-1,TROP-2,GA7331,tumor-associated calcium si...

Human HEK293 Cells
TROP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.4 kDa and the accession number is P09758.
TMPY-01870 IL-9 Protein, Human, Recombinant (His)

P40,interleukin 9,HP40,白细胞介素,IL-9,白介素

Human Baculovirus Insect Cells
IL-9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is P15248.
TMPY-05176 AMH Protein, Human, Recombinant (His)

MIS,anti-Mullerian hormone,MIF

Human HEK293 Cells
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi...
TMPY-05102 CD122/IL2RB Protein, Rat, Recombinant (His)

interleukin 2 receptor, β,interleukin 2 re...

Rat HEK293 Cells
CD122/IL2RB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P26896.
TMPY-05054 Notch 4 Protein, Human, Recombinant (His)

INT3,notch 4

Human Baculovirus Insect Cells
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is involved in the development and patterning of the central nervous systems. It regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The NOTCH4 gene has also been identified as a possibl...
TMPY-02019 CD59 Protein, Human, Recombinant (His)

MIN2,MAC-IP,G344,EL32,FLJ92039,HRF-20,EJ30,HRF20,MSK21,MGC23...

Human HEK293 Cells
CD59 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P13987-1.
TMPY-01686 B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)

β-2 microglobulin,beta-2 microglobulin

Human HEK293 Cells
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P61769.
TMPY-01741 CD19 Protein, Mouse, Recombinant (His)

AW495831,CD19 molecule

Mouse HEK293 Cells
CD19 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is P25918.
TMPY-00570 Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)

ALPI,PALP,PLAP,PLAP-1,alkaline phosphatase, placent...

Human P. pastoris (Yeast)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
TMPY-00690 Carbonic Anhydrase 9 Protein, Human, Recombinant (His)

Carbonic Anhydrase IX,MN,CAIX

Human HEK293 Cells
Carbonic Anhydrase 9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.5 kDa and the accession number is A0A0S2Z3D0.
TMPY-04329 Vimentin Protein, Human, Recombinant (His)

CTRCT30,HEL113,vimentin

Human Baculovirus Insect Cells
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ...
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重组蛋白

NT-4 Protein, Human, Recombinant
Cat.No: TMPY-05804
Species: Human
Expression System: E. coli
Neurotrophin 3 Protein, Human, Recombinant
Cat.No: TMPY-04069
Species: Human
Expression System: E. coli
CD73 Protein, Human, Recombinant (His)
Cat.No: TMPY-01851
Species: Human
Expression System: HEK293 Cells
CD73 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01342
Species: Mouse
Expression System: HEK293 Cells
Neurotensin Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00561
Species: Human
Expression System: HEK293 Cells
NTS1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00982
Species: Cynomolgus
Expression System: HEK293 Cells
NTS1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01162
Species: Mouse
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06907
Species: Human
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05580
Species: Human
Expression System: HEK293 Cells
Prostatic Acid Phosphatase Protein, Human, Recombinant (His)
Cat.No: TMPY-02155
Species: Human
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05454
Species: Human
Expression System: HEK293 Cells
NT-proBNP Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00874
Species: Human
Expression System: E. coli
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02672
Species: Mouse
Expression System: HEK293 Cells
ACPP Protein, Human, Recombinant (His)
Cat.No: TMPJ-00514
Species: Human
Expression System: HEK293 Cells
NTAQ1 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-00489
Species: Human
Expression System: E. coli
NT5C3A/NT5C3 Protein, Human, Recombinant
Cat.No: TMPY-02893
Species: Human
Expression System: E. coli
MGAT2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01092
Species: Human
Expression System: HEK293 Cells
NT5C Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00858
Species: Human
Expression System: E. coli
NT5C1A Protein, Human, Recombinant (His)
Cat.No: TMPH-01197
Species: Human
Expression System: P. pastoris (Yeast)
NGF Protein, Human, Recombinant (E. colli)
Cat.No: TMPJ-01469
Species: Mouse
Expression System: E. coli
BDNF Protein, Human/Murine/Rat, Recombinant
Cat.No: TMPJ-00135
Species: Human,Mouse,Rat
Expression System: E. coli
FGF-17 Protein, Human, Recombinant
Cat.No: TMPY-03104
Species: Human
Expression System: E. coli
PHGDH Protein, Human, Recombinant (His)
Cat.No: TMPY-02801
Species: Human
Expression System: E. coli
TGF alpha Protein, Human, Recombinant
Cat.No: TMPY-03958
Species: Human
Expression System: E. coli
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
Cat.No: TMPY-02219
Species: H1N1
Expression System: E. coli
HIST3H2A Protein, Human, Recombinant
Cat.No: TMPY-02521
Species: Human
Expression System: E. coli
MMP-12 Protein, Human, Recombinant (catalytic domain)
Cat.No: TMPY-02869
Species: Human
Expression System: E. coli
SULT1A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02062
Species: Human
Expression System: E. coli
Recombinant Protein G
Cat.No: TMPY-00105
Species:
Expression System: E. coli
FGF-8a Protein, Human, Recombinant
Cat.No: TMPY-00005
Species: Human
Expression System: E. coli
IFN gamma Protein, Human, Recombinant (E. coli)
Cat.No: TMPY-06983
Species: Human
Expression System: E. coli
Serum Amyloid P Protein, Human, Recombinant (His)
Cat.No: TMPY-03195
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03203
Species: Rat
Expression System: HEK293 Cells
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
Cat.No: TMPK-00305
Species: Human
Expression System: HEK293 Cells
ANXA2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00785
Species: Mouse
Expression System: E. coli
CNTF Protein, Human, Recombinant (His)
Cat.No: TMPY-01864
Species: Human
Expression System: E. coli
c-Kit Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01802
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01936
Species: Mouse
Expression System: HEK293 Cells
NKp44/NCR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01807
Species: Human
Expression System: HEK293 Cells
TROP-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01262
Species: Human
Expression System: HEK293 Cells
IL-9 Protein, Human, Recombinant (His)
Cat.No: TMPY-01870
Species: Human
Expression System: Baculovirus Insect Cells
AMH Protein, Human, Recombinant (His)
Cat.No: TMPY-05176
Species: Human
Expression System: HEK293 Cells
CD122/IL2RB Protein, Rat, Recombinant (His)
Cat.No: TMPY-05102
Species: Rat
Expression System: HEK293 Cells
Notch 4 Protein, Human, Recombinant (His)
Cat.No: TMPY-05054
Species: Human
Expression System: Baculovirus Insect Cells
CD59 Protein, Human, Recombinant (His)
Cat.No: TMPY-02019
Species: Human
Expression System: HEK293 Cells
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)
Cat.No: TMPY-01686
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01741
Species: Mouse
Expression System: HEK293 Cells
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Cat.No: TMPY-00570
Species: Human
Expression System: P. pastoris (Yeast)
Carbonic Anhydrase 9 Protein, Human, Recombinant (His)
Cat.No: TMPY-00690
Species: Human
Expression System: HEK293 Cells
Vimentin Protein, Human, Recombinant (His)
Cat.No: TMPY-04329
Species: Human
Expression System: Baculovirus Insect Cells
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