579
348
9
5
156
Cat. No. | Product Name | ||
---|---|---|---|
L4300 | Wnt/Hedgehog/Notch 通路化合物库 | 237 compounds | |
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。 | |||
L7900 | 成骨分子库 | 317 compounds | |
317 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8110 | 细胞重编程化合物库 | 1813 compounds | |
1813 种重编程信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选 | |||
L4700 | 免疫/炎症分子化合物库 | 4720 compounds | |
4720 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选; | |||
L4800 | 血管生成库 | 1353 compounds | |
1353 个高潜力的抑制或促进血管生成的小分子集合,可用于药物靶点开发、血管生成机理研究的高通量筛选,高内涵筛选; | |||
L2500 | 人内源代谢化合物库 | 499 compounds | |
499 种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选; | |||
L2170 | 肿瘤免疫治疗小分子化合物库 | 449 compounds | |
449 种靶向肿瘤免疫治疗靶点的小分子,可用于高通量和高内涵筛选,是研究肿瘤免疫治疗的有力工具; | |||
L2400 | 内分泌激素分子库 | 784 compounds | |
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2501 | 人内源代谢化合物库 Plus | 1283 compounds | |
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。 |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0060 |
Estrogen Receptor inhibitor kit
Estrogen Receptor inhibitor kit |
||
CL0083 |
Dehydrogenase inhibitor kit
Dehydrogenase inhibitor kit |
||
CL0095 |
Hedgehog signaling pathway inhibitor/activator kit
Hedgehog signaling pathway inhibitor/activator kit |
||
CL0126 |
Androgen Receptor antagonist kit
Androgen Receptor antagonist kit |
||
CL0110 |
Progesterone Receptor agonist/antagonist/modulator kit
Progesterone Receptor agonist/antagonist/modulator kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6073 |
OG-L002
|
Histone Demethylase; Monoamine Oxidase; HSV | Chromatin/Epigenetic; Microbiology/Virology; Neuroscience |
OG-L002 是一种高度选择性的 LSD1有效抑制剂,IC50为 0.02 μM。它抑制HSV IE 基因的表达,还是单胺氧化酶抑制剂,对 MAO-A 和 MAO-B 的IC50分别为 1.38 μM 和 0.72 μM。 | |||
T39362 |
OG 488, acid
|
||
OG 488, a fluorescent pH indicator (acid), is widely used in biochemistry and neurosciences, offering numerous applications. | |||
T39402 |
OG 488, SE
Oregon green 488 succinimidyl ester |
||
Oregon Green 488 succinimidyl ester (OG 488, SE), a fluorescent pH indicator, finds extensive applications in the fields of biochemistry and neuroscience. | |||
T8336 |
OGG1-IN-08
OGG1-IN-O8 |
Others | Others |
OGG1-IN-08 (OGG1-IN-O8) 是 8-氧鸟嘌呤 DNA 糖基酶-1 抑制剂(IC50:0.22 μM)。它能够减少 OGG1 的糖基化酶和裂解酶活性。 | |||
T35617 |
Mitoguazone
MGBG,Methyl-GAG |
Apoptosis; HIV Protease | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
Mitoguazone (Methyl-GAG) 是一种可透过血脑屏障的选择性的 S-腺苷-蛋氨酸脱羧酶 (S-adenosyl-methionine decarboxylase) 抑制剂,可破坏多胺的生物合成。Mitoguazone 是一种具有抗肿瘤活性的合成多羰基衍生物,可抑制 HIV DNA 整合到单核细胞和巨噬细胞中的细胞 DNA 中,诱导细胞凋亡 (apoptosis)。Mitoguazone 具可用于预防急性白血病,霍奇金淋巴瘤和非霍奇金淋巴瘤。 | |||
T3076 |
GLPG0634 analog
GLPG0634 analogue |
Tyrosine Kinases; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
GLPG0634 analog (GLPG0634 analogue) 是一种 JAK 广谱性抑制剂,对 JAK1/JAK2/JAK3 的 IC50值为 50 到 200 nM 之间。 | |||
T65550 |
Gefitinib analog III
4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate |
Others | Others |
Gefitinib analog III (4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate) 具有潜在的抗炎和抗肿瘤活性,可用于研究其在生物体内的相互作用和活性。 | |||
T30998L |
COG-1410 acetate
COG-1410 acetate(878009-24-6 Free base) |
Apoptosis | Apoptosis |
COG-1410 acetate 是一种载脂蛋白 E 衍生肽,可用于神经系统疾病的研究。 | |||
T7657L |
MOG peptide (35-55) , mouse, rat acetate
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate,MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base) |
Others | Others |
Myelin Oligodendrocyte Glycoprotein (MOG) peptide (35-55) , mouse, rat acetate 是MOG peptide (35-55)衍生物。 MOG peptide (35-55)是髓鞘少突胶质细胞糖蛋白 (MOG) 免疫原肽的 一部分。MOG peptide (35-55) 特异性作用于 CD4+ T 细胞,能够给诱导实验性自身免疫性脑脊髓炎 (EAE) 动物模型。MOG peptide (35-55) , mouse, rat acetate(149635-73-4 Free base)是MOG peptide (35-55)衍生物。 MOG peptide (35-55)是髓鞘少突胶质细胞糖蛋白 (MOG) 免疫原肽的 一部分,可用于研究与免疫相关的疾病。 | |||
T3576 |
CPI-455 analogue
CPI-455 analogue |
Others | Others |
CPI-455 analogue (CPI-455 analogue) 是 CPI-455 的结构类似物,CPI-455 是一种 KDM5 抑制剂。 | |||
T9224 |
CH5424802 analog
|
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
CH5424802 analog 是一种选择性 ALK 抑制剂,能够阻断耐药性看门人突变体。 | |||
T1052 |
Proglumide
二丙谷酰胺 |
cholecystokinin | GPCR/G Protein |
Proglumide (Binoside) 是一种非肽的、口服具有活性的胆囊收缩素(CCK)-A/B 受体拮抗剂。它能够选择性阻断 CCK 在中枢神经系统中的作用。它能够抑制胃分泌,具有保护胃十二指肠粘膜的能力,并表现出抗癫痫和抗氧化活性。 | |||
T11684 |
Isoguvacine hydrochloride
1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride,异四氢烟酸 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) 是 GABA 受体激动剂。它与大鼠突触皮质膜结合并激活 α1β2γ2S、α2β2γ2S、α3β2γ2S、α5β2γ2S 和 ρ1 亚基 GABAA 受体。 | |||
T4382 |
Proguanil hydrochloride
Paludrine hydrochloride,盐酸氯胍,Chlorguanide hydrochloride,Chloroquanil |
Others; Dehydrogenase; DNA/RNA Synthesis; Antifolate; Parasite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Others |
Proguanil hydrochloride (Chloroquanil) 是一种双胍类抗疟疾剂,在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。 | |||
T78646 |
Estrogen receptor antagonist 8
|
Estrogen/progestogen Receptor | Endocrinology/Hormones |
Estrogen receptor antagonist 8 作为一种雌激素受体(ER)拮抗剂,具有抗子宫活性和潜在的抗肿瘤活性,可用于研究卵巢功能障碍。 | |||
T9718 |
Ethoxylated hydrogenated castor oil
|
Others | Others |
Ethoxylated hydrogenated castor oil 是一种聚乙二醇与天然蓖麻油的混合物,可用于水包油 (o/w) 乳浊液的乳化和增溶,是动物实验的良好助溶剂。 | |||
T2377 |
Pilaralisib analogue
XL147 analogue,SAR245408 |
Apoptosis; DNA-PK; PI3K | Apoptosis; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
Pilaralisib analogue (XL147 analogue) 是一种选择性和可逆的 I 类 PI3K 抑制剂,用于 PI3Kα/δ/γ。 | |||
T21024 |
Ornithine-α-ketoglutarate
L-Ornithine-α-ketoglutarate,Ornithine α ketoglutarate,L Ornithine α ketoglutarate,Ornithine α-ketoglutarate,OKG,鸟氨酸α-酮戊二酸 |
Others | Others |
Ornithine-α-ketoglutarate (L-Ornithine-α-ketoglutarate) 是由 2 个鸟氨酸分子和 1 个 α-酮戊二酸分子形成的盐。 Ornithine-α-ketoglutarate (L-Ornithine-α-ketoglutarate) 可改善慢性营养不良(例如老年人)和急性营养不良患者(尤其是烧伤和创伤患者)的营养状况。 | |||
T12444 |
Phentolamine Analogue 1
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Phentolamine Analogue 1 是 phentolamine 类似物。其中Phentolamine 是非选择性alpha-adrenergic 拮抗剂 。 | |||
T21335 |
Fluorogestone acetate
Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880,氟孕酮醋酸酯 |
Others | Others |
Fluorogestone acetate (Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880) 显示出高效力且活性持续时间短,并且在生理上与孕酮相似。 FGA 的效力大约是黄体酮的 20-25 倍。 | |||
T15090 |
Decoglurant
RO4995819 |
GluR | Neuroscience |
Decoglurant (RO4995819) 是 mGluR2和 mGluR3的负变构调制器,有抗抑郁作用。 | |||
T37185 |
D-(-)-3-Phosphoglyceric acid disodium
3-Phospho-D-glyceric acid disodium |
Others | Others |
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) 是糖酵解、糖原合成以及丝氨酸、甘氨酸、苏氨酸生物合成等过程中的重要中间体,竞争性抑制酵母烯醇化酶 (enolase)。作为中间体它还在植物、真核细胞以及原核细胞许多的生物合成信号通路中发挥许多作用。 | |||
T6819 |
Desogestrel
Org-2969,去氧孕烯,Desogen,Desogestrelum,Cerazette |
Estrogen/progestogen Receptor; Progesterone Receptor | Endocrinology/Hormones; Others |
Desogestrel (Cerazette) 是第三代孕激素类似物,存在于许多口服避孕制剂中。 | |||
T6192 |
Alogliptin
SYR-322,阿格列汀,阿洛利停 |
Ferroptosis; Proteasome; DPP-4 | Apoptosis; Proteases/Proteasome; Ubiquitination |
Alogliptin (SYR-322) 是一种具有选择性口服活性的DPP-4的抑制剂,IC50值小于 10 nM,比对 DPP-8 和 DPP-9 的抑制性高 10000 倍以上,可研究 2 型糖尿病。 | |||
T3089 |
6-Thioguanine
6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine,6-硫代鸟嘌呤 |
Apoptosis; DNA Methyltransferase; SARS-CoV; Endogenous Metabolite; DUB; Autophagy | Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Ubiquitination |
6-Thioguanine (2-Amino-6-purinethiol) 是一种抗白血病和免疫抑制剂,是 SARS 和 MERS 冠状病毒木瓜样蛋白酶抑制剂,也抑制 USP2的活性,IC50值分别为 25 μM 和 40 μM。 | |||
T3456 |
Fisogatinib
BLU554,BLU 554,BLU-554 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Fisogatinib (BLU-554) 是高效的、选择性的、口服具有活力的 FGFR4 抑制剂(IC50:5 nM)。它在依赖FGFR4信号传导的肝细胞癌模型中具有显著的抗肿瘤活性。 | |||
T20511 |
6-Thioguanosine
6-Mercaptoguanosine,NSC29422,NSC 29422,NSC-29422 |
Others | Others |
6-Thioguanosine (6-Mercaptoguanosine) 是一种活性核苷,是 Azathioprine 的代谢物,是低分子量凝胶剂。6-Thioguanosine 具有免疫抑制作用,可用于研究RNA 双螺旋结构的形成。 | |||
T9013 |
Autogramin-2
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate |
Autophagy | Autophagy |
Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) 有效抑制由饥饿诱导的自噬,IC50为 0.27 μM。它也抑制 Rapamycin,通过抑制 mTORC1 诱导的自噬,IC50为 0.14 μM。 | |||
T9186 |
Ervogastat
PF-06865571 |
Transferase | Metabolism |
Ervogastat (PF-06865571) 是一种有效且耐受性良好的二酰基甘油酰基转移酶 2 抑制剂。 Ervogastat 可降低非酒精性脂肪性肝炎 (NASH) 中的脂肪变性和肝脏甘油三酯水平。 | |||
T7944 |
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
PIK-III analogue |
PI3K | PI3K/Akt/mTOR signaling |
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) 是一种有效的选择性 VPS34抑制剂( IC50 : 15 nM)。 | |||
T17039 |
Terbogrel
BIBV 308SE |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Terbogrel 是一种可口服的 、具有选择性 thromboxane A2 受体拮抗剂(IC50 约为 10 nM),是一种 thromboxane A2 synthase 抑制剂(IC50 约为 10 nM)。Terbogrel 是一种抗血小板化合物,可抑制血小板聚集,是预防血栓的潜在化合物。 | |||
T19712 |
Levoglucosenone
|
Others | Others |
Levoglucosenone 具有细胞毒性。它对抗人肝癌细胞系。 | |||
T60221 |
Tabernanthalog
TBG |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Tabernanthalog (TBG) 是一种5-HT2A 激动剂。在啮齿类动物中,Tabernanthalog 已被发现可促进结构神经可塑性并产生抗抑郁作用。 | |||
T11177 |
Elinogrel
PRT060128 |
P2Y Receptor | GPCR/G Protein; Neuroscience |
Elinogrel (PRT060128) 是一种竞争性和可逆的血小板 P2Y12 拮抗剂,IC50 为 20 nM,并表现出有效的抗血小板作用。 | |||
T1103 |
Aminoglutethimide
DL-Aminoglutethimide,氨鲁米特,BA-16038,NSC-330915 |
Aromatase | Endocrinology/Hormones |
Aminoglutethimide (BA-16038) 是一种芳香酶抑制剂,IC50=10 μM,用于治疗晚期 BREAST Y。 | |||
T67906 |
Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate)
|
||
Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate)是一种化合物,是复方他汀类磷酸衍生物。 | |||
T17033 |
Temanogrel
APD791 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Temanogrel (APD791) 是一种高度选择性的 5-HT2A 受体拮抗剂,Ki 值为 4.9 nM。 | |||
TP1820L |
Osteogenic Growth Peptide, OGP acetate
Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base) |
Others | Others |
Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base) 是一种短的、天然存在的 14 聚体生长因子肽,存在于血清中,浓度为 μM。成骨生长肽 OGP 是局部骨髓损伤全身成骨反应机制的关键因素。 | |||
T40380 |
17α-Hydroxyprogesterone acetate
|
Others | Others |
17α-Hydroxyprogesterone acetate 具有孕激素活性和抗炎活性。 | |||
T76782 |
Mogamulizumab
KW-0761 |
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
Mogamulizumab (KW-0761) 是一种针对 T 细胞 CC 趋化因子受体 4 的 单克隆抗体。Mogamulizumab 具有抗癌活性,通过抗体依赖性细胞毒性 (ADCC) 消除肿瘤细胞,可用于研究癌症、成人T细胞白血病/淋巴瘤 (ATLL)、皮肤T细胞淋巴瘤(CTCL)。 | |||
T15645 |
Pamicogrel
KBT3022,帕米格雷 |
COX | Immunology/Inflammation; Neuroscience |
Pamicogrel (KBT3022) 是一种环氧合酶 (COX) 抑制剂。 | |||
T21582L |
Acetyl Angiotensinogen (1-14), porcine Acetate
Acetyl Angiotensinogen (1-14), porcine Acetate(66641-26-7 Free base) |
Others | Others |
Acetyl Angiotensinogen (1-14), porcine Acetate 是一种肽,序列为 AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH。由血管紧张素原基因编码的蛋白质被称为前血管紧张素原或血管紧张素原前体。 | |||
T20950 |
MK-8245 analog
MK-8245-analog,MK 8245 analog |
Others | Others |
MK-8245 analog 是 MK-8245 的类似物,MK-8245 是一种肝脏靶向的硬脂酰辅酶 A 去饱和酶 (SCD) 抑制剂。它可用于治疗血脂异常和糖尿病。 | |||
T2401 |
Alogliptin Benzoate
苯甲酸阿格列汀,SYR 322,Alogliptin(SYR-322)benzoate |
Ferroptosis; Proteasome; DPP-4 | Apoptosis; Proteases/Proteasome; Ubiquitination |
Alogliptin Benzoate (SYR 322) 是一种有效且特异性的 DPP-4 抑制剂 ,IC50值小于 10 nM,其选择性比 DPP-8/9 高 10,000 倍以上,可用于研究 2 型糖尿病。 | |||
T1939 |
DMOG
Dimethyloxalylglycine,Dimethyloxallyl Glycine,Dimethyloxaloylglycine,二甲基草酰甘氨酸 |
HIF/HIF Prolyl-Hydroxylase; HIF; Autophagy | Angiogenesis; Autophagy; Chromatin/Epigenetic; Metabolism |
DMOG (Dimethyloxalylglycine) 是 α-酮戊二酸辅因子的拮抗剂,是一种 HIF 脯氨酰羟化酶抑制剂,可导致蛋白HIF-1α的积聚和稳定,诱导细胞自噬。它是一种促血管生成剂,在结肠炎和腹泻动物模型中起保护作用。 | |||
T10858 |
COH34 analog 1
|
Others | Others |
COH34 analog 1 是一种 COH34 氧化类似物,可用于合成具有活性的化合物。 | |||
T7216 |
Mirogabalin
DS5565 |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Mirogabalin (DS5565) 是一种高效的、选择性的 α2δ-1 配体,作用于电压敏感性钙通道复合体的α2δ-1亚基。 | |||
T12770 |
RR-11a analog
aza-peptide Michael acceptor, 7a |
Parasite | Microbiology/Virology |
RR-11a analog (aza-peptide Michael acceptor, 7a) 是一种天冬酰胺酰内肽酶抑制剂,对阴道毛滴虫中的 AE1、蓖麻硬蜱中的 AE 和曼氏血吸虫中的 AE 的 IC50 分别为 4.5 nM、4.5 nM 和 31 nM。 | |||
T27630 |
Isbogrel
CV4151,CV-4151,CV 4151 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Isbogrel (CV4151)是一种小分子血栓素A2合成酶(TXA2 synthase)抑制剂,可用来研究心律失常、短暂性脑缺血发作和血栓形成。 | |||
T8239 |
Cromoglicic acid
|
Others | Others |
Cromoglicic acid 可防止肥大细胞释放炎性化学物质,例如组胺。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37526 |
2-Oleoylglycerol
2-Oleoyl Glycerol,2-OG,2-Monoolein |
GPR | Endocrinology/Hormones; GPCR/G Protein |
2-Oleoylglycerol 是一种存在于棕榈仁、葵花籽和米糠中的脂质。2-Oleoylglycerol 可当作一种 GPR119 激动剂,具有神经保护作用,可诱导胰高血糖素样肽 1 (GLP-1) 分泌。2-Oleoylglycerol 可用于非酒精性脂肪性肝炎造模。 | |||
TN1475 |
Caulophyllogenin
Segetalic acid |
IL Receptor; TNF; PPAR; Immunology/Inflammation related | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism |
Caulophyllogenin 是一种部分 PPARγ 激动剂 (EC50 = 12.6 μM),来源于 Kalopanax pictus (五加科) 的茎皮。 Caulophyllogenin 抑制促炎细胞因子分泌,可用于预防和治疗炎症性疾病、2 型糖尿病、肥胖和代谢综合征的研究。 | |||
T19344 |
Glycogen, Mussel
α-1,6 葡聚糖,Glycogen |
Endogenous Metabolite | Metabolism |
Glycogen, Mussel 是一种糖酵解的中间产物和高能磷酸盐,它是人类、动物、真菌和细菌的一种能量储存形式。 | |||
TN7109 |
Prosaikogenin G
|
RAAS | Endocrinology/Hormones |
Prosaikogenin G 是一种从柴胡的根中分离出的化合物,是 Saikosaponin d 在胃肠道中的衍生物。Prosaikogenin G 对 Angiotensin II 诱导的大鼠系膜细胞增殖具有明显的抑制作用,同时对肾脏有保护作用。 | |||
T4S1312 |
Gypsogenin-3-O-glucuronide
丝石竹皂苷元3-O-Β-D-葡萄糖醛酸甲酯,Methyl gypsogenin 3-O-beta-D-glucuronopy,丝石竹皂苷元-3-O-β-D-葡萄糖醛酸甲酯 |
Others | Others |
Gypsogenin-3-O-glucuronide (Methyl gypsogenin 3-O-beta-D-glucuronopy) 是一种皂角苷前体,普遍存在于满天星属植物中。 | |||
T5S1262 |
Methylophiopogonanone A
|
Others | Others |
Methylophiopogonanone A 是从Ophiopogon japonicas 提取到的黄酮类化合物,具有抗炎和抗氧化的特性。它通过调节 MMP-9 和紧密连接蛋白的表达来减轻 BBB 破坏的能力,具有治疗脑 I/R 损伤的潜力。 | |||
T3920 |
Pseudoginsenoside F11
Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11 |
Others; Endogenous Metabolite | Metabolism; Others |
Pseudoginsenoside F11 (Ginsenoside A1) 从人参根和叶中分离得到。PF11在一系列心血管和中枢神经系统疾病中具有广泛的保护作用。 | |||
T19382 |
Isoguanine
2-羟基-6-氨基嘌呤,异鸟嘌呤 |
Nucleoside Antimetabolite/Analog | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Isoguanine 是一种嘌呤碱基,是鸟嘌呤的异构体,可作为有机合成的砌块。 | |||
TN3460 |
Asebogenin
|
Antifungal | Microbiology/Virology |
Asebogenin 是从丹参中分离出来的化合物,具有抗真菌活性,对GPVI 诱导的血小板反应有抑制作用,抑制促炎刺激诱导的 NET 形成。 | |||
T4244 |
Methylophiopogonone A
|
Others | Others |
Methylophiopogonone A 是一种异黄酮,从 Ophiopogon japonicas 根部分离得到,具有抗炎作用。 | |||
T4743 |
Uridine 5′-diphosphoglucose disodium salt
二磷酸尿苷葡萄糖二钠盐,UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal |
Endogenous Metabolite; P2Y Receptor | GPCR/G Protein; Metabolism; Neuroscience |
Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) 是一种内源性核苷酸糖,参与代谢中的糖基转移酶反应。它是 P2Y14 受体的激动剂,EC50为 0.35 μM。 | |||
T5098 |
Isochlorogenic acid A
3,5-CQA,异绿原酸 A,3,5-Dicaffeoylquinic acid,金银花 |
Reactive Oxygen Species; HBV; Endogenous Metabolite | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) 是一种天然酚酸,具有抗氧化和抗炎活性。 | |||
T3785 |
11-oxo-mogroside V
11-oxo Mogroside V,11-氧罗汉果苷 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
11-oxo-mogroside V (11-oxo Mogroside V) 是一种天然甜味剂,具有显著的抗氧化作用。它对活性氧物质具有显著的抑制作用,作用于O2-,H2O2和*OH,EC50分别为 4.79,16.52 和 146.17 μg/mL。 | |||
T3S0860 |
Gitogenin
|
UGT | Metabolism |
Gitogenin 是一种从Tribulus longipetalus 整株中分离出来的天然类固醇,是一种 UDP-葡萄糖醛酸转移酶 1A4 (UGT1A4) 和 α-葡萄糖苷酶的选择性抑制剂,其IC50分别为 0.69 µM (使用三氟拉嗪为底物) 和 37.2 μM,对人类主要细胞色素 P450 亚型的活性无抑制作用。 | |||
T3S1589 |
Notoginsenoside Fa
|
Others | Others |
Notoginsenoside Fa 是一种原人参二醇型皂苷,从P. notoginseng 提取出来得到,有激活和恢复退化脑功能的潜能。 | |||
TN6726 |
methyl chlorogenate
|
NF-κB | NF-κB |
methyl chlorogenate 是从 Eriobotrya japonica 中分离得到的,它是 NFkappaB 的抑制剂。 | |||
T25476 |
Gypsogenin
丝石竹皂苷元 |
Bcr-Abl | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Gypsogenin (639-14-5) 是一种天然存在的生化物质,具有明显的抗血管生成活性和对 H460 的细胞毒性,拥有抗 ABL1 激酶和抗慢性骨髓性白血病作用。 | |||
T2S0250 |
Pseudoprotogracillin
伪原纤细薯蓣皂苷 |
Others | Others |
Pseudoprotogracillin 是一种从薯蓣科中提取的甾体皂苷类天然产物。 | |||
T2961 |
Notoginsenoside R1
Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1 |
Apoptosis; ERK; Beta Amyloid | Apoptosis; MAPK; Neuroscience |
Notoginsenoside R1 (Sanchinoside R1) 是一种从三七中分离出来的皂苷,具有抗氧化、抗炎、抗血管生成和抗凋亡的活性。它有神经保护和抗缺血/再灌注损伤的心脏保护作用。 | |||
T0478 |
Progesterone
孕酮,Pregn-4-ene-3,20-dione |
Estrogen/progestogen Receptor; Progesterone Receptor; Opioid Receptor; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience; Others |
Progesterone (Pregn-4-ene-3,20-dione) 是类固醇激素,能够调节月经周期。 | |||
T6185 |
Gambogic Acid
藤黄酸,Beta-Guttiferrin,藤黄酸 A,Guttatic Acid,Guttic Acid |
BCL; Autophagy | Apoptosis; Autophagy |
Gambogic Acid (Guttic Acid) 是来自藤黄树的一种藤黄树脂,抑制 Bcl-XL、Bcl-2、Bcl-W、Bcl-B、Bfl-1和 Mcl-1,IC50分别为 1.47 μM、1.21 μM、2.02 μM、0.66 μM、1.06 μM 和 0.79 μM。 | |||
TN4673 |
(+)-Nortrachelogenin
Wikstromol,荛花酚 |
Apoptosis; HIV Protease; PI3K; Antifection | Apoptosis; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
(+)-Nortrachelogenin 是一种从 Wikstroemia indica C.A. Meyer (百里香科)中分离出来的木脂素。 (+)-Nortrachelogenin 具有抗白血病活性。 | |||
T6S1587 |
Notoginsenoside R2
三七皂苷R2,20(S)-Notoginsenoside R2,Ginsenoside Ng-R2 |
Others; Nrf2 | Immunology/Inflammation; Others |
Notoginsenoside R2 (20(S)-Notoginsenoside R2) 是一种新分离三七皂苷,表现出对6-OHDA 诱导的氧化应激及细胞凋亡的保护作用。 | |||
T8288 |
14-Deoxyandrographolide
去氧穿心莲内酯,14-去氧穿心莲内酯 |
Apoptosis; Others | Apoptosis; Others |
14-Deoxyandrographolide 是穿心莲中的一种天然产物,是一种钙通道阻断剂,具有保肝功效。它通过诱导 TNFRSF1A 的释放,使肝细胞对 TNF-α 介导的凋亡脱敏。 | |||
T9218 |
Andrograpanin
19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元 |
p38 MAPK | MAPK |
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) 是来自穿心莲的一种天然产物,具有抗炎和抗感染活性。 | |||
TJS1748 |
Methyl protogracillin
山药 |
Antifection | Microbiology/Virology |
Methyl protogracillin 是来自 Dioscorea collettii var. hypoglauca 的天然产物,具有抗癌活性。 | |||
T2805 |
Chlorogenic Acid
NSC-407296,3-O-Caffeoylquinic acid,Heriguard,绿原酸 |
Others; Influenza Virus; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite; Antibacterial | Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others |
Chlorogenic Acid (NSC-407296) 是咖啡和茶中的主要酚类化合物。它具有多种生物作用。 | |||
TN2335 |
Prosaikogenin D
Prosapogenin D,柴胡次皂苷D |
Others | Others |
Prosaikogenin D (Prosapogenin D) 是一种天然产物,从柴胡 Buleurum bicaule Helm 的根中提取,具有抗癌活性。 | |||
T6S1440 |
Loganic acid
马钱苷酸,Loganate |
Others | Others |
Loganic acid (Loganate) 是从山茱萸果实中分离得到的环烯醚萜。它具有很强的自由基清除活性,对重金属介导的毒性有显著的细胞保护作用。它能调节饮食引起的动脉粥样硬化和氧化还原状态。 | |||
T4S1519 |
Pseudoginsenoside RT5
拟人参皂苷RT5 |
Others | Others |
Pseudoginsenoside RT5 分离于 Panax quinquefolium 中。它通过促进神经生长和提高认知能力,具有抗癫痫、抗抑郁活性,还具有抗菌、抗肿瘤、抗疟疾等活性。 | |||
T12090 |
Mogroside I E1
罗汉果苷 I E1 |
Others | Others |
Mogroside I E1 是三萜糖苷,是非糖类甜味剂。其中 Mogroside 的甜度比蔗糖高,具有抗氧化,抗糖尿病和抗癌特性。 | |||
T8300 |
Mogroside IV-E
mogroside Ive,罗汉果甙 IV |
Antioxidant | oxidation-reduction |
Mogroside IV-E 是一种非糖类甜味剂,是一种三萜糖苷。Mogroside 比蔗糖更甜,具有抗氧化,抗糖尿病和抗癌作用。 | |||
T6S1256 |
Ruscogenin
|
NOS; NF-κB; NOD-like Receptor (NLR) | Immunology/Inflammation; NF-κB |
Ruscogenin 是一种重要甾体皂苷元,提取自麦冬。它能够抑制 TXNIP/NLRP3炎症体激活和 MAPK 途径,改善脑缺血诱导的血脑屏障功能障碍,具有显著抗血栓、抗炎作用。 | |||
T16685 |
Purpurogallin
红倍酚,红陪酚 |
Xanthine Oxidase | Metabolism |
Purpurogallin 是一种从栎属植物中提取的天然酚,具有显著的黄嘌呤氧化酶抑制作用,其IC50=0.2 µM,具有抗氧化和抗炎作用。 | |||
T5701 |
OPHIOPOGONIN D
麦冬皂苷 D,麦冬皂苷D |
RAAS; Calcium Channel; NF-κB; PPAR | DNA Damage/DNA Repair; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism; NF-κB |
Ophiopogonin D 是从麦冬的块茎中分离的一种天然产物,是罕见的天然存在的 C29甾体糖苷。它是一种 CYP2J3 诱导剂,用于炎症和心血管疾病的相关研究。 | |||
T5S0814 |
Berberine hydrogen sulphate
Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate |
Antibacterial | Microbiology/Virology |
Berberine hydrogen sulphate (Umbellatine Sulfate) 是一种从几种植物中提取的生物碱,对多种微生物具有抗菌活性,包括革兰氏阳性和革兰氏阴性细菌、真菌和原生动物。 | |||
T7924 |
8-Bromoguanosine
|
Others | Others |
8-Bromoguanosine 是鸟苷的溴化衍生物。它是通过细胞内机制激活淋巴细胞发挥免疫刺激作用。 | |||
TN4675 |
Nortrachelogenin
(-)-Wikstromol,(-)-Nortrachelogenin |
Apoptosis; Antifungal | Apoptosis; Microbiology/Virology |
Nortrachelogenin ((-)-Wikstromol) 可从 Partrinia scabiosaefolia 提取得到,具有抗真菌活性,可诱导膜破坏和半胱天冬酶依赖性细胞凋亡. | |||
TQ0185 |
14-Deoxy-11,12-didehydroandrographolide
AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide |
NF-κB | NF-κB |
14-Deoxy-11,12-didehydroandrographolide (AP10) 是一种 Andrographolide 的类似物,能够抑制 NF-κB 活性。 | |||
T2S0257 |
Dehydroandrographolide succinate
|
Others; Influenza Virus | Microbiology/Virology; Others |
Dehydroandrographolide succinate 是从中药穿心莲中提取的一种天然产物,具有免疫刺激、抗感染和抗炎作用,有潜力研究病毒性肺炎和病毒性上呼吸道感染。 | |||
T3S1196 |
mogroside IV
|
Others | Others |
Mogroside IV 是一种从罗汉果提取物中分离得到的三萜糖苷。它是非糖类甜味剂,甜度比蔗糖高。它具有抗氧化,抗糖尿病和抗癌作用。 | |||
TN1982 |
Neoglycyrol
|
Others | Others |
Neoglycyrol 是分离自甘草的根中的化合物。它是由传统专利药通脉养心丸中筛选得到,具有潜在心肌保护作用。 | |||
TN1934 |
Mogroside IIA1
Mogroside II-A1,罗汉果苷II A1 |
Others; NO Synthase | Immunology/Inflammation; Others |
Mogroside IIA1 (Mogroside II-A1) 是从罗汉果的果实中分离得到的。Mogroside IIA1 是一种无糖甜味剂,比蔗糖更甜。 Mogroside IIA1 具有抗氧化、抗糖尿病和抗癌活性。 | |||
TN1056 |
Mogroside IIe
|
IL Receptor | Immunology/Inflammation |
Mogroside IIe 是一种天然来源的三萜糖苷,作为非糖类甜味剂,Mogroside 比蔗糖更甜。Mogroside 具有抗氧化,抗糖尿病和抗癌活性。 | |||
T2S1193 |
Mogroside III-A1
罗汉果苷 III-A1 |
Others | Others |
Mogroside III-A1 是一种来自罗汉果 Swingle 的三萜糖苷。 Mogroside III-A1 一种无糖甜味剂。 | |||
TN7230 |
Butyl chlorogenate
|
Others | Others |
Butylchlorogenate 是一种忍冬、Urceola rosea 中分离出的天然化合物。 | |||
TN2346 |
Mogrol
|
ERK; AMPK; STAT | Chromatin/Epigenetic; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells |
Mogrol 是罗汉果中的一种天然产物,通过抑制 ERK1/2 和 STAT3 通路,减少 CREB 激活和激活 AMPK 信号传导发挥作用。 | |||
TN5845 |
Neochlorogenic acid methyl ester
5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate,新绿原酸甲酯 |
Antioxidant; HBV | Microbiology/Virology; oxidation-reduction |
Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) 来源于毛蒿和黑色苦莓(Aronia melanocarpa)果实。Neochlorogenic acid methyl ester 显示出抗 HBV 活性、抗氧化活性和醌还原酶活性,CD 为 6.7 μM。 | |||
T41017 |
Epigambogic acid
|
||
Epigambogic acid 是一种来自藤黄的小分子化合物,具有抗肿瘤、止咳、祛痰和抗炎活性。 | |||
TN6798 |
Progoitrin
|
Others | Others |
Progoitrin 是一种硫代葡萄糖苷,与受感染作物中占主导地位。它对甲状腺活性具有抑制作用。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04899 |
OGN/Osteoglycin Protein, Human, Recombinant (His)
OIF,OG,osteoglycin,SLRR3A |
Human | HEK293 Cells |
OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor-beta and may regulate osteoblast differentiation. OGN is broadly expressed in the gall bladder, endometrium, and other tissues. OGN reduced Zeb-1 expression via EGFR/Akt leading to inhibition of epith... | |||
TMPY-03345 |
Sonic Hedgehog Protein, Mouse, Recombinant (His)
Hhg1,Hxl3,9530036O11Rik,Dsh,Hx,sonic hedgehog,M1000... |
Mouse | HEK293 Cells |
Sonic Hedgehog Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is Q62226. | |||
TMPY-02594 |
Noggin/NOG Protein, Mouse, Recombinant (hFc)
noggin |
Mouse | HEK293 Cells |
Noggin/NOG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51 kDa and the accession number is P97466. | |||
TMPY-01082 |
Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (95% Homology) (His)
G Protein, RSV |
RSV | HEK293 Cells |
Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (95% Homology) (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is P27022-1. | |||
TMPY-05346 |
CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)
SpyCas9 |
Streptococcus pyogenes | Baculovirus Insect Cells |
CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 163 kDa and the accession number is Q99ZW2. | |||
TMPY-05202 |
Noggin/NOG Protein, Human, Recombinant
noggin,SYNS1,SYM1 |
Human | HEK293 Cells |
Noggin/NOG Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.1 kDa and the accession number is Q13253. | |||
TMPY-01686 |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)
β-2 microglobulin,beta-2 microglobulin |
Human | HEK293 Cells |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P61769. | |||
TMPY-00890 |
Noggin/NOG Protein, Human, Recombinant (hFc)
SYM1,SYNS1,Noggin |
Human | HEK293 Cells |
Noggin/NOG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.8 kDa and the accession number is Q13253. | |||
TMPH-00009 |
OGT Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
OGT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 62.5 kDa and the accession number is O15294. | |||
TMPY-06987 |
Wnt Surrogate/Wnt3a Protein, Recombinant
Wnt 3a,wnt3a,Wnt-3a |
Human | HEK293 Cells |
Wnt Surrogate/Wnt3a Protein, Recombinant is expressed in HEK293 mammalian cells with hFc tag. | |||
TMPJ-01065 |
Noggin/NOG Protein, Mouse, Recombinant (His)
Nog,Noggin |
Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi... | |||
TMPY-01384 |
Endoglin/CD105 Protein, Human, Recombinant (His)
endoglin,HHT1,END,ORW1 |
Human | HEK293 Cells |
Endoglin/CD105 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.3 kDa and the accession number is A0A024R878. | |||
TMPY-00978 |
Progranulin Protein, Human, Recombinant (His)
PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granulin Precursor,Pr... |
Human | HEK293 Cells |
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1. | |||
TMPH-00363 |
Cyanovirin-N homolog Protein, Ceratopteris richardii, Recombinant (His)
CV-N homolog,Cyanovirin-N homolog |
Ceratopteris richardii | P. pastoris (Yeast) |
Mannose-binding lectin. Cyanovirin-N homolog Protein, Ceratopteris richardii, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.4 kDa and the accession number is P86326. | |||
TMPJ-01236 |
B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)
Beta-2-Microglobulin,β-2-Microglobulin,B2M |
Cynomolgus | HEK293 Cells |
B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 14 KDa and the accession number is Q8SPW0. | |||
TMPH-00405 |
Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc)
Acyl-CoA dehydrogenase, short-chain specific,SCAD,B... |
Clostridium acetobutylicum | E. coli |
Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-01870 |
Plasminogen Protein, Human, Recombinant (His)
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Human | E. coli |
Plasminogen Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.0 kDa and the accession number is P00747. | |||
TMPH-00509 |
Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc)
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Fruit fly | E. coli |
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins. Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.0 kDa and the accession number is Q27869. | |||
TMPH-02078 |
Semenogelin-1/SEMG1 Protein, Human, Recombinant (His & SUMO)
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Human | E. coli |
Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.; Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone. Sem... | |||
TMPH-03092 |
Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc)
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Phaseolus vulgaris | E. coli |
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation. Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22.9 kDa and the accession number is P02234. | |||
TMPY-05011 |
Haptoglobin Protein, Rat, Recombinant (His)
haptoglobin |
Rat | HEK293 Cells |
Haptoglobin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is A6IZ24. | |||
TMPK-00761 |
B2M/beta 2-Microglobulin Protein, Mouse, Recombinant (hFc)
B2M/β 2-Microglobulin,Beta-2-microglobulin... |
Mouse | HEK293 Cells |
The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors. | |||
TMPH-01973 |
Proteoglycan 4 Protein, Human, Recombinant (His)
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Human | P. pastoris (Yeast) |
Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.; Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages. Proteoglycan 4 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 1... | |||
TMPH-00122 |
Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His)
AA9 family lytic polysaccharide monooxygenase A,cel61A,AA9A,... |
Aspergillus kawachii | E. coli |
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates. Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.2 kDa and the accession number is Q96WQ9. | |||
TMPH-01457 |
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)
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HHV-6B | E. coli |
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs. Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P52539. | |||
TMPH-00312 |
Malate dehydrogenase Protein, Brucella abortus, Recombinant (His & Myc & SUMO)
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Brucella abortus | E. coli |
Catalyzes the reversible oxidation of malate to oxaloacetate. Malate dehydrogenase Protein, Brucella abortus, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.7 kDa and the accession number is B2S881. | |||
TMPH-02398 |
ASA dehydrogenase Protein, Legionella pneumophila, Recombinant (His)
Aspartate-beta-semialdehyde dehydrogenase,asd,Aspar... |
Legionella pneumophila | E. coli |
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate. | |||
TMPH-00503 |
60S ribosomal protein L10 Protein, Drosophila melanogaster, Recombinant (His)
QM protein homolog,Large ribosomal subunit protein ... |
Fruit fly | E. coli |
60S ribosomal protein L10 Protein, Drosophila melanogaster, Recombinant (His) is expressed in E. coli. | |||
TMPH-02701 |
Haptoglobin Protein, Mouse, Recombinant (His)
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Mouse | E. coli |
Haptoglobin Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.9 kDa and the accession number is Q61646. | |||
TMPY-02232 |
Angiotensinogen Protein, Mouse, Recombinant (His)
AngI,Serpina8,angiotensinogen (serpin peptidase inh... |
Mouse | HEK293 Cells |
Angiotensinogen Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is P11859. | |||
TMPY-01615 |
Endoglin/CD105 Protein, Mouse, Recombinant (His)
Endo,CD105,S-endoglin,AI528660,endoglin,AI... |
Mouse | HEK293 Cells |
Endoglin/CD105 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.2 kDa and the accession number is Q63961. | |||
TMPY-02413 |
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His)
HEL-S-26,HEL-216,IDP,IDCD,PICD,IDH,isocitrate dehydrog |
Human | E. coli |
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 48 kDa and the accession number is O75874. | |||
TMPY-02565 |
MOG Protein, Mouse, Recombinant (aa 30-149, His)
B230317G11Rik,myelin oligodendrocyte glycoprotein |
Mouse | E. coli |
MOG Protein, Mouse, Recombinant (aa 30-149, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16 kDa and the accession number is Q61885. | |||
TMPY-02283 |
Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (93% Homology) (His)
G Protein |
RSV | Baculovirus Insect Cells |
Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (93% Homology) (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P27022-1. | |||
TMPJ-00457 |
OGG1 Protein, Human, Recombinant
OGH1,N-Glycosylase/DNA Lyase,DNA-(Apurinic or Apyri... |
Human | E. coli |
Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3’ to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma. | |||
TMPH-02975 |
Wilms tumor protein homolog Protein, Mouse, Recombinant (His & Myc)
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Mouse | E. coli |
Wilms tumor protein homolog Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 56.7 kDa and the accession number is P22561. | |||
TMPY-01221 |
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)
NgR1,reticulon 4 receptor,NgR,Rtn4r,NOGOR |
Mouse | HEK293 Cells |
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q99PI8. | |||
TMPK-00019 |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (hFc)
Beta-2-microglobulin,B2M/β 2-Microglobulin... |
Human | HEK293 Cells |
To assess whether beta-2 microglobulin (B2M) has effects on articular chondrocytes that would implicate B2M involvement in osteoarthritis (OA) pathogenesis.The average B2M level in OA synovial fluid is significantly higher than that found in normal synovial fluid. B2M is highly expressed in OA cartilage and synovial fluid compared to normal, and suggest that B2M may have effects on chondrocyte function that could contribute to OA pathogenesis. | |||
TMPH-02795 |
Myoglobin Protein, Mouse, Recombinant (His & Myc)
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Mouse | HEK293 Cells |
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Myoglobin Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 21.9 kDa and the accession number is P04247. | |||
TMPH-00042 |
Haloalkane dehalogenase Protein, Agrobacterium tumefaciens, Recombinant (His & Myc)
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Agrobacterium fabrum | E. coli |
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Haloalkane dehalogenase Protein, Agrobacterium tumefaciens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q8U671. | |||
TMPH-01500 |
NANOG Protein, Human, Recombinant (His & SUMO)
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Human | E. coli |
NANOG Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 50.6 kDa and the accession number is Q9H9S0. | |||
TMPH-03609 |
Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO)
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Streptomyces viridochromogenes | E. coli |
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is Q57146. | |||
TMPH-03597 |
Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)
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Streptococcus pyogenes | E. coli |
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is Q48RM7. | |||
TMPH-03653 |
RNU2 Protein, Ustilago sphaerogena, Recombinant (B2M & His)
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Ustilago sphaerogena | E. coli |
N/A. RNU2 Protein, Ustilago sphaerogena, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 26.4 kDa and the accession number is P00654. | |||
TMPH-03034 |
MG218.1 homolog Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)
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Mycoplasma pneumoniae | E. coli |
MG218.1 homolog Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-03968 |
Secretogranin II Protein, Human, Recombinant (His)
EM66,SgII,SN,CHGC,secretogranin II |
Human | HEK293 Cells |
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KITL / kit ligand also belongs to the family of dimeric transmembrane growth factors. The soluble form of KIT ligand is a secreted protein. Mast cells are thought to participate in a variety of immune responses, such as parasite resistance and the allergic reaction. Mast cell devel... | |||
TMPH-03379 |
Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His)
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Rat | E. coli |
May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation. Involved in the regulation of short-term and long-term synaptic plasticity. Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 31.7 kDa and the accession number is Q62876. | |||
TMPY-06667 |
Ara h 9.0101 Protein, Arachis hypogaea, Recombinant
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Arachis hypogaea | P. pastoris (Yeast) |
Ara h 9.0101 Protein, Arachis hypogaea, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 18.9 kDa. | |||
TMPY-03144 |
Nogo Receptor/RTN4R Protein, Human, Recombinant (His)
NGR,reticulon 4 receptor,NOGOR |
Human | HEK293 Cells |
Nogo Receptor/RTN4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9BZR6. | |||
TMPK-01200 |
Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His)
NGR,NOGOR,RTN4R,NgR1,Nogo receptor,Nog... |
Cynomolgus | HEK293 Cells |
NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes. | |||
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