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Search Results for " erk "

Targets Recommended: PERK ERK ERK

222

抑制剂 & 化合物

72

天然产物

1

化合物库

4

TargetMol 试剂盒

43

重组蛋白

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Cat. No.	Product Name
L2192	抗胰腺癌化合物库		2238 compounds
	2238 种与胰腺癌相关的化合物，可以用于高通量和高内涵筛选；

化合物库

抗胰腺癌化合物库

Cat.No: L2192

Compounds: 2238

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0114	ERK inhibitor kit ERK inhibitor kit
CL0109	Ras inhibitor kit Ras inhibitor kit
CL0091	MEK inhibitor kit MEK inhibitor kit
CL0075	c-Kit inhibitor kit c-Kit inhibitor kit

TargetMol 试剂盒

ERK inhibitor kit

Cat.No: CL0114

Ras inhibitor kit

Cat.No: CL0109

MEK inhibitor kit

Cat.No: CL0091

c-Kit inhibitor kit

Cat.No: CL0075

Cat. No.	Product Name	Target	Signaling Pathways
T36675	ERK-IN-4 ERK Inhibitor	ERK	MAPK
	ERK-IN-4 是一种具有细胞渗透性的 ERK 抑制剂，具有潜在的抗增殖作用，可用于研究免疫功能异常引起的疾病。
T9141	ERK-IN-3 ASN007 free base	ERK	MAPK
	ERK-IN-3 (ASN007 free base) 是一种有效的口服活性 ERK 抑制剂，以低 IC50 值抑制 ERK1/2，可用于研究由 RAS 突变驱动的癌症。
T11224	Rineterkib ERK-IN-1	ERK; Raf	MAPK
	Rineterkib (ERK-IN-1) 是口服有效的RAF 和ERK1/2的抑制剂，与 KRAS-突变型非小细胞肺癌、BRAF-突变型非小细胞肺癌、KRAS-突变型胰腺癌、KRAS -突变型结肠癌和 KRAS-突变型卵巢癌尤为相关。
T3166	VX-11e Vertex-11e,VTX-11e,TCS ERK 11e	ERK; GSK-3; FLT; CDK; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; MAPK; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
	VX-11e (TCS ERK 11e) 是可口服的ERK 高效选择性抑制剂，Ki 值小于 2 nM。
T5184	ERK5-IN-1	ERK	MAPK
	ERK5-IN-1 是 ERK5抑制剂，IC50为 87 nM。它也抑制 LRRK2[G2019S]，IC50为 26 nM。
T5535	ERK5-IN-2	ERK	MAPK
	ERK5-IN-2 是具有口服活性，亚微摩尔效力，选择性ERK5抑制剂，对ERK5和ERK5 MEF2D 的IC50s 分别是 0.82 和 3 μM。它抑制肿瘤异种移植生长和碱性成纤维细胞生长因子驱动的基质胶塞血管生成。
T39453	ERK-IN-3 benzenesulfonate
	ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK . ERK-IN-3 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancers driven by RAS mutations.
T11225	ERK-IN-2	ERK	MAPK
	ERK-IN-2 是ERK2抑制剂，IC50值为 1.8 nM。 ERK-IN-2 在剂量 >10 μM 可能引起脱靶毒性和/或脱靶活性。
T82443	ERK-CLIPTAC	PROTACs	PROTAC
	ERK-CLIPTAC为PROTAC类化合物，具有促进ERK降解的功能。
T74997	ERK-IN-6
	ERK-IN-6 (compound 6g) 是有效的食管鳞状细胞癌 (ESCC) 的抗增殖剂。ERK-IN-6 通过ERK 通路诱导细胞凋亡。ERK-IN-6 可用于食管鳞状细胞癌的研究。
T71316	ERK Inhibitor II (Negative control)
	ERK InhibitorII (Negative control)为高效的细胞外信号调节激酶(ERK)抑制剂，能抑制胰岛素受体(Insulin Receptor)激活，适用于糖尿病研究。
T77731	ERK5-IN-6	ERK	MAPK
	ERK5-IN-6 是一种有效的 ERK5 激酶抑制剂。ERK5-IN-6 具有抗增殖活性、抗惊厥活性和抗肿瘤活性，可用于研究中枢神经系统相关疾病。
T80543	STE-MEK1(13) ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂	ERK	MAPK
	STE-MEK1(13)（Ste-MPKKKPTPIQLNP-NH2）为一细胞渗透性ERK1/2抑制剂，IC50值为13-30μM，可抑制ERK1/2磷酸化。
T72517	ERK-IN-2 free base
	ERK-IN-2 free base是ERK2抑制剂，IC50为1.8 nM。使用剂量>10 μM时，可能引起脱靶毒性和/或脱靶活性。
T77734	ERK5-IN-5	ERK	MAPK
	ERK5-IN-5 是一种有效的细胞外信号调节激酶 5 (ERK5）抑制剂，有抗癌活性和潜在的抗惊厥活性，抑制 A549 细胞增殖。
T11226	ERK1/2 inhibitor 1	ERK	MAPK
	ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
T8472	ERK1/2 inhibitor 2 ASTX-029,ASTX029	ERK	MAPK
	ERK1/2 inhibitor 2 (ASTX029) 是一种选择性和可口服的细胞外信号调节激酶 1 和 2 (ERK 1/2) 抑制剂，具有潜在的抗肿瘤活性。
T10827	CK2/ERK8-IN-1 TMCB	Apoptosis; ERK; Casein Kinase; Pim; DYRK	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	CK2/ERK8-IN-1 (TMCB) 是一种酪蛋白激酶 2 (CK2) (Ki 为 0.25 µM) 和 ERK8 (MAPK15, ERK7) 的双重抑制剂，IC50 均为 0.50 μM。CK2/ERK8-IN-1 也与 PIM1，HIPK2 和 DYRK1A 结合，Ki 值分别为 8.65 µM，15.25 µM 和 11.9 µM。
T5358	Longdaysin	ERK; Casein Kinase; CDK	Cell Cycle/Checkpoint; MAPK; Metabolism; Stem Cells
	Longdaysin 是一种 CK1α 和 CK1δ 的抑制剂，IC50为5.6和8.8 µM。它还抑制ERK2，IC50值为52 µM。它是Wnt/β-catenin 信号通路的抑制剂，通过阻断CK1δ/ε依赖性 Wnt 信号通路发挥抗肿瘤作用。
T6066	SCH772984	ERK; MEK	MAPK
	SCH772984 是高选择性和 ATP 竞争性ERK 抑制剂，对 ERK1 和 ERK2 的IC50分别为 4 和 1 nM。它在含有 BRAF 或 RAS 突变的 MAPK 抑制剂初治和 MAPK 抑制剂耐药细胞中具有抗肿瘤活性。
T4091	Temuterkib LY3214996	ERK	MAPK
	Temuterkib (LY3214996) 是高效选择性的ERK1和ERK2抑制剂，IC50为 5 nM，具有潜在的抗肿瘤活性。
T10479	BAY885	ERK	MAPK
	BAY885 是选择性 ERK5抑制剂，IC50为 35 nM。
T14894	CC-90003	ERK	MAPK
	CC-90003 是不可逆选择性ERK 1/2抑制剂，具有抗肿瘤活性。
T14360	AX-15836	ERK	MAPK
	AX-15836是一种选择性 ERK5抑制剂，IC50值为8 nM。
TQ0005	KO-947	ERK	MAPK
	KO-947是选择性ERK1/2激酶抑制剂，具有潜在的抗肿瘤作用。
T6818	DEL-22379 DEL22379	Apoptosis; ERK	Apoptosis; MAPK
	DEL-22379 是一种水溶性 ERK 二聚化抑制剂，IC50约为 0.5 μM。
T10429	Tizaterkib AZD-0364	ERK	MAPK
	Tizaterkib (AZD-0364) 是一种选择性ERK2抑制剂，IC50为 0.6 nM。
T1956	FR 180204 FR180204	Apoptosis; ERK	Apoptosis; MAPK
	FR 180204 是一种 ATP 竞争性的选择性ERK 抑制剂，对ERK1和ERK2的Ki 值分别为 0.31 μM 和 0.14 μM，IC50值分别为0.51 μM 和0.33 μM。
T6511	Ravoxertinib GDC-0994	ERK	MAPK
	Ravoxertinib (GDC-0994) 是可口服的ERK 激酶抑制剂，抑制ERK1和ERK2的IC50分别为 6.1 和 3.1 nM。
T8418	DCLK1-IN-1	Others	Others
	DCLK1-IN-1 是选择性的、体内相容的双皮质素样激酶1DCLK1激酶结构域化学探针。它抑制 DCLK1 和 DCLK2 激酶。它具有低毒性，可以研究 DCLK1 的生物学特性，确定其在肿瘤中的作用，如 DCLK1+胰腺导管腺癌。
T4985	Neticonazole Hydrochloride	Antifungal	Microbiology/Virology
	Neticonazole hydrochloride 是一种咪唑衍生物，具有抗感染和抗癌作用。它也是一种长效抗真菌剂。
T7953	BpV(HOpic) bpV (HOpic)	PTEN	PI3K/Akt/mTOR signaling
	BpV(HOpic) (bpV (HOpic)) 是 PTEN 选择性抑制剂，IC50=14 nM。BpV(HOpic) 具有神经保护作用。
T36674	DMU-212	Apoptosis; ERK	Apoptosis; MAPK
	DMU-212 是具有口服活性的白藜芦醇的甲基化衍生物，表现出抗分裂、抗增殖、抗氧化和促进细胞凋亡的活性。它通过诱导凋亡和激活ERK1/2蛋白阻止有丝分裂。
T16143	MRTX-1257	Ras	GPCR/G Protein; MAPK
	MRTX-1257 是选择性的、可口服的不可逆共价KRAS G12C 抑制剂，其在 H358 细胞中测得 KRAS 依赖 ERK 磷酸化的IC50值为 900 pM。
T7425	RU-301	TAM Receptor	Tyrosine Kinase/Adaptors
	RU-301 是一种新型 pan-TAM 受体抑制剂，能够在 TAM 的 Gas6 和 Ig1 结构域之间的界面处结合发挥 pan-TAM 抑制活性，Kd=12 μM，IC50=10 μM。
T9303	MRTX1133	Ras	GPCR/G Protein; MAPK
	MRTX1133 是一种 KRAS G12D 抑制剂 (KD=0.2 pM)，具有强效性、选择性和非共价性。MRTX1133 对 KRAS G12D 突变的肿瘤具有抑制活性，而对 KRAS 野生型肿瘤无抑制活性。
T6948	Pluripotin SC1	ERK; Raf; S6 Kinase	MAPK; PI3K/Akt/mTOR signaling
	Pluripotin (SC1) 是ERK1和RasGAP 的双重抑制剂，KD 分别为 98 和 212 nM。它还抑制RSK1、RSK2、RSK3和RSK4，IC50分别为 0.5、2.5、3.3 和 10.0 μM。
T8973	HS-1793	Others	Others
	HS-1793 是 resveratrol 类似物，可以诱导细胞凋亡，在多种癌细胞中有抗肿瘤的能力。
T21302	UNC569 UNC 569	TAM Receptor	Tyrosine Kinase/Adaptors
	UNC569 (UNC 569) 是一种ATP 竞争性的、可逆、具有口服活性的Mer 激酶抑制剂，其IC50=2.9 nM，Ki=4.3 nM。它还抑制Axl 和Tyro3，IC50分别为 37 nM 和 48 nM。它可用于研究急性淋巴细胞白血病和非典型畸胎瘤/横纹肌瘤。
T1843	XMD8-92	ERK; BMI-1; Epigenetic Reader Domain	Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK
	XMD8-92 是 ERK5 (BMK1)/BRD4的有效抑制剂，Kd 分别为80和190 nM。它抑制 DCAMKL2、PLK4 和 TNK1的 Kd 分别为190、600和890nm，具有抗癌活性。
T21295	BIX02189 BIX 02189	ERK; MEK	MAPK
	BIX02189 是一种有效的选择性 MEK5 和 ERK5 抑制剂，IC50分别为 1.5 和 59 nM。
T12069	MK-8353 SCH900353	ERK	MAPK
	MK-8353 (SCH900353) 是口服有效的ERK1/2选择性抑制剂，IC50分别为 23.0 nM 和 8.8 nM。它显示出抗肿瘤活性。
T2029	Bohemine	ERK; CDK	Cell Cycle/Checkpoint; MAPK
	Bohemine 是一种合成的选择性CDK 抑制剂，是嘌呤类似物，具有抗癌活性。它对Cdk2/cyclin E、Cdk2/cyclin A 和Cdk9/cyclin T1的IC50分别为 4.6 μM、83 μM 和 2.7 μM。
T4496	LM22B-10 LM22B10	ERK; Trk receptor; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	LM22B-10 是TrkB/TrkC 神经营养因子受体激活剂，诱导体内外TrkB、TrkC、AKT 和ERK 的活化。
T1842	XMD17-109 XMD17 109,ERK5-IN-1	ERK	MAPK
	XMD17-109 (ERK5-IN-1) 是一种特异性的ERK-5抑制剂，在 HEK293 细胞系中的EC50为 4.2 μM。
T14042	4-P-PDOT 4-phenyl-2- propionamidotetralin	Melatonin Receptor; MT Receptor	GPCR/G Protein; Neuroscience
	4-P-PDOT (4-phenyl-2- propionamidotetralin) 是一种选择性和亲和性的褪黑激素受体拮抗剂，可显著抵消褪黑激素介导的抗氧化作用。它对MT2的选择性是 MT1 的 300 倍以上。
T2623	PD98059 PD 98059	ERK; Aryl Hydrocarbon Receptor; MEK; Autophagy	Autophagy; Immunology/Inflammation; MAPK
	PD98059 是一种 MEK 抑制剂，抑制 MEK1 和 MEK2 (IC50=2/50 μM)，具有非 ATP 竞争性。PD98059 也是一种 AHR 的配体而起拮抗作用。PD98059 可以抑制细胞自噬。
T7506	Yoda 1	Piezo Channel	Membrane transporter/Ion channel
	Yoda 1 是Piezo1激动剂，能够激活纯化的 Piezo1 通道。
T5364	TBHQ tert-Butylhydroquinone,特丁基对苯二酚,叔丁基氢醌	Apoptosis; ERK; Others; Ferroptosis; Nrf2; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; MAPK; Others
	TBHQ (tert-Butylhydroquinone) 是一种抗氧化剂，可通过对氧化还原敏感的转录因子 Nrf2 诱导抗氧化反应。它也是一种ERK 激活剂，逆转 Dehydrocorydaline 对黑素瘤细胞增殖的抑制作用。
T21980	PD 198306	MEK	MAPK
	PD 198306 是一种具有抗痛觉过敏作用的 MAPK/ERK 激酶 (MEK) 选择性抑制剂。 PD 198306 可降低链脲佐菌素诱导的活性 ERK1 水平升高。

化合物

Cat.No: T36675

Synonym: ERK Inhibitor

Target: ERK

Cat.No: T9141

Synonym: ASN007 free base

Target: ERK

Cat.No: T11224

Synonym: ERK-IN-1

Target: ERK, Raf

Cat.No: T3166

Synonym: Vertex-11e,VTX-11e,TCS ERK 11e

Target: ERK, GSK-3, FLT, CDK, Aurora Kinase

Cat.No: T5184

Target: ERK

Cat.No: T5535

Target: ERK

ERK-IN-3 benzenesulfonate

Cat.No: T39453

Cat.No: T11225

Target: ERK

Cat.No: T82443

Target: PROTACs

Cat.No: T74997

ERK Inhibitor II (Negative control)

Cat.No: T71316

Cat.No: T77731

Target: ERK

Cat.No: T80543

Synonym: ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂

Target: ERK

ERK-IN-2 free base

Cat.No: T72517

Cat.No: T77734

Target: ERK

ERK1/2 inhibitor 1

Cat.No: T11226

Target: ERK

ERK1/2 inhibitor 2

Cat.No: T8472

Synonym: ASTX-029,ASTX029

Target: ERK

CK2/ERK8-IN-1

Cat.No: T10827

Synonym: TMCB

Target: Apoptosis, ERK, Casein Kinase, Pim, DYRK

Cat.No: T5358

Target: ERK, Casein Kinase, CDK

Cat.No: T6066

Target: ERK, MEK

Cat.No: T4091

Synonym: LY3214996

Target: ERK

Cat.No: T10479

Target: ERK

Cat.No: T14894

Target: ERK

Cat.No: T14360

Target: ERK

Cat.No: TQ0005

Target: ERK

Cat.No: T6818

Synonym: DEL22379

Target: Apoptosis, ERK

Cat.No: T10429

Synonym: AZD-0364

Target: ERK

Cat.No: T1956

Synonym: FR180204

Target: Apoptosis, ERK

Cat.No: T6511

Synonym: GDC-0994

Target: ERK

Cat.No: T8418

Target: Others

Neticonazole Hydrochloride

Cat.No: T4985

Target: Antifungal

Cat.No: T7953

Synonym: bpV (HOpic)

Target: PTEN

Cat.No: T36674

Target: Apoptosis, ERK

Cat.No: T16143

Target: Ras

Cat.No: T7425

Target: TAM Receptor

Cat.No: T9303

Target: Ras

Cat.No: T6948

Synonym: SC1

Target: ERK, Raf, S6 Kinase

Cat.No: T8973

Target: Others

Cat.No: T21302

Synonym: UNC 569

Target: TAM Receptor

Cat.No: T1843

Target: ERK, BMI-1, Epigenetic Reader Domain

Cat.No: T21295

Synonym: BIX 02189

Target: ERK, MEK

Cat.No: T12069

Synonym: SCH900353

Target: ERK

Cat.No: T2029

Target: ERK, CDK

Cat.No: T4496

Synonym: LM22B10

Target: ERK, Trk receptor, Akt

Cat.No: T1842

Synonym: XMD17 109,ERK5-IN-1

Target: ERK

Cat.No: T14042

Synonym: 4-phenyl-2- propionamidotetralin

Target: Melatonin Receptor, MT Receptor

Cat.No: T2623

Synonym: PD 98059

Target: ERK, Aryl Hydrocarbon Receptor, MEK, Autophagy

Cat.No: T7506

Target: Piezo Channel

Cat.No: T5364

Synonym: tert-Butylhydroquinone,特丁基对苯二酚,叔丁基氢醌

Target: Apoptosis, ERK, Others, Ferroptosis, Nrf2, Autophagy

Cat.No: T21980

Target: MEK

Cat. No.	Product Name	Target	Signaling Pathways
TN2346	Mogrol	ERK; AMPK; STAT	Chromatin/Epigenetic; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Mogrol 是罗汉果中的一种天然产物，通过抑制 ERK1/2 和 STAT3 通路，减少 CREB 激活和激活 AMPK 信号传导发挥作用。
T6S0655	Corynoxeine	ERK	MAPK
	Corynoxeine 是从钩藤中分离的一种天然产物，是 PDGF-BB 诱导血管平滑肌细胞 (VSMCs) 增殖过程中的 ERK1/ERK2抑制剂。
T3856	Tenuifoliside A	ERK; Others	MAPK; Others
	Tenuifoliside A 是从远志分离得到的一种天然产物，具有抗凋亡、抗抑郁、抗炎和神经保护活性。
T3857	magnolin 木兰脂素,(+)-Magnolin,木兰苷	ERK	MAPK
	Magnolin 是辛夷的一种主要成分，靶向作用于ERK1和ERK2，IC50值分别为 87 和 16.5 nM，可抑制Ras/ERKs/RSK2信号通路。它在体内外降低肾脏氧化应激，抑制 caspase-3 活性，并增加 Bcl-2 表达，具有抗炎和抗氧化作用。
T5S1982	Periplocin Periplocoside,杠柳毒苷	Apoptosis; Others	Apoptosis; Others
	Periplocin (Periplocoside) 是从黑龙骨中分离出的一种强心类固醇。它可促进肿瘤细胞凋亡并抑制肿瘤生长。它通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径，具有促进伤口愈合的潜力。
T3844	Deltonin 三角叶薯蓣皂苷	ERK; Others; Akt; Endogenous Metabolite	Cytoskeletal Signaling; MAPK; Metabolism; Others; PI3K/Akt/mTOR signaling
	Deltonin 是从盾叶薯蓣中得到的一种甾体皂苷，抑制ERK1/2和AKT 的活化，具有抗肿瘤活性。
TN3967	Epieriocalyxin A	ERK; BCL; ROS; Caspase; DNA/RNA Synthesis; JNK	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Proteases/Proteasome
	Epieriocalyxin A 可以抑制 Caco-2 结肠癌细胞的生长。它可能是未来结肠癌治疗的潜在药物。
T6947	Piperlongumine PPLGM,荜茇酰胺,Piplartine	Apoptosis; ERK; Ferroptosis; Reactive Oxygen Species; ROS; Antibacterial; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology; NF-κB
	Piperlongumine (Piplartine) 是一种来自 Piper longum L. 的天然生物碱，具有抗炎、抗菌、抗血管生成、抗氧化、抗肿瘤和抗糖尿病等活性。它选择性地杀死癌细胞并增强活性氧的水平。它具有抗心肌纤维化的作用，通过抑制 ERK1/2 信号通路抑制肌成纤维细胞的转化。
TL0016	Sulforaphene 油菜	Apoptosis; ERK; EGFR; NF-κB	Angiogenesis; Apoptosis; JAK/STAT signaling; MAPK; NF-κB; Tyrosine Kinase/Adaptors
	Sulforaphene 是从萝卜种子中分离出来的天然产物，对鹿茸幼苗的 ED50 约为 2 x 10 -4 M。它通过抑制 EGFR、p-ERK1/2、NF-κB 和其他信号促进癌细胞凋亡并抑制迁移。
TN1410	Asperulosidic acid ASPA,车叶草苷酸	ERK; NF-κB	MAPK; NF-κB
	Asperulosidic acid (ASPA) 是从白花蛇舌草药中提取的一种环烯醚萜苷，具有抗肿瘤、抗氧化和抗炎作用。它通过抑制 NF-κB 和丝裂原活化蛋白激酶信号通路抑制炎性细胞因子释放发挥抗炎作用。
T3876	Loureirin B 龙血素B,龙血素 B	PAI-1; ERK; Potassium Channel; JNK	MAPK; Membrane transporter/Ion channel; Metabolism
	Loureirin B 是从剑叶龙血树中分离到的一种黄酮，是 PAI-1抑制剂，IC50值为 26.10 μM。它抑制 KATP，以及 ERK 和 JNK 的磷酸化，具有抗糖尿病的功效。
TN1721	Gypenoside L	ERK; p38 MAPK; Calcium Channel; NF-κB; ROS	Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Metabolism; NF-κB
	Gypenoside L 是存在于绞股蓝中的一种皂苷，可增加 SA-β-半乳糖苷酶活性，促进衰老相关分泌细胞因子的产生。它还可以激活p38和ERK MAPK 通路和NF-κB 通路以诱导衰老，具有抗肿瘤和抗炎活性。
TMS2181	trans-Zeatin (E)-Zeatin,玉米素	ERK; MEK; Endogenous Metabolite	MAPK; Metabolism
	trans-Zeatin ((E)-Zeatin) 是植物细胞分裂素，可抑制紫外线诱导的MEK/ERK 的活化，在细胞生长、分化和分裂中起着重要的作用。
T6S0619	Pachymic acid 3-O-Acetyltumulosic acid,茯苓酸	ERK; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Pachymic acid (3-O-Acetyltumulosic acid) 是来自茯苓的一种三萜，可抑制Akt 和ERK 信号传导途径。
T5727	CAFESTOL 咖啡醇,咖啡油醇	ERK; NF-κB; COX; PGE Synthase	Immunology/Inflammation; MAPK; Neuroscience; NF-κB
	Cafestol 是咖啡特有的一种二萜，可靶向 AP-1 抑制ERK，有化学预防、抗肿瘤、保肝、抗氧化和抗炎作用。它通过抑制NF-kB 活化途径强烈的抑制 PGE2的产生，还抑制 LGE 激活的 RAW264.7 细胞中的PGE2产生和环氧合酶(COX-2)的 mRNA 表达。
T5S0761	Nitidine chloride	Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite	Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的，具有抗疟疾活性。它通过多个靶点通路，起抗癌作用，抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
T3001	Honokiol 和厚朴酚,NSC 293100	ERK; HCV Protease; MEK; Akt; Autophagy	Autophagy; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Honokiol (NSC-293100) 是厚朴提取物的活性成分，靶向多种信号分子，具有抗氧化，抗炎，抗血管生成和抗癌活性。它可抑制 Akt 的激活并增强 ERK1/ERK2 的磷酸化。
T2973	Astragaloside IV AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV	MMP; ERK; Estrogen/progestogen Receptor; JNK	Endocrinology/Hormones; MAPK; Proteases/Proteasome
	Astragaloside IV (AS-IV) 是从黄芪中分离得到的一种皂苷，抑制ERK1/2和JNK 激活，在乳腺癌细胞 MDA-MB-231 中，下调(MMP)-2和(MMP)-9的信号通路。
T6427	Butein 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因	Apoptosis; EGFR; Others; PDE; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
	Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂，也是蛋白酪氨酸激酶抑制剂，还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路，靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
T13265	Urolithin B 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮	ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Urolithin B 是一种 ellagitannins 的肠道微生物代谢产物，具有抗炎和抗氧化作用。它也是骨骼肌质量的调节因子，通过减少 IκBα 的磷酸化和降解来抑制 NF-κB 活性，并抑制 JNK、ERK 和 Akt 的磷酸化，并增强 AMPK 的磷酸化。
T6S0117	Avicularin Fenicularin,扁蓄苷	ERK	MAPK
	Avicularin (Fenicularin) 具有抗过敏、抗炎、保肝、抗氧化、抗肿瘤等活性。它能通过调节 NF-κB(p65)、COX-2 和 PPAR-γ 的活性来改善人类肝细胞癌。在 LPS 刺激的 RAW 264.7 巨噬细胞中，它通过抑制 ERK 信号通路产生抗炎活性。
T5S1058	Triptonide 雷公藤内酯酮,PG 492,NSC 165677	Apoptosis; Wnt/beta-catenin; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Stem Cells
	Triptonide (PG 492) 是从雷公藤中鉴定出的一种天然产物，是一种 Wnt 信号抑制剂，其 IC50约为 0.3 nM。它具有免疫抑制、抗炎、避育、神经保护和抗淋巴瘤作用。
TN2354	Methylnissolin 3-Hydroxy-9,10-dimethoxyptercarpan,黄芪紫檀烷,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷	ERK; PDGFR	Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) 是从黄芪中分离的一种天然产物，可抑制血小板衍生生长因子(PDGF)-BB 诱导的细胞增殖，IC50为 10 μM。。它通过抑制 ERK1/2MAP 激酶级联反应抑制 PDGF-BB 诱导的血管平滑肌细胞增殖。它还抑制 PDGF-BB 诱导的细胞外信号调节激酶 1/2 (ERIC1/2) 丝裂原活化蛋白 (MAP) 激酶的磷酸化，具有抗菌和抗癌作用。
T2532	Tauroursodeoxycholate Taurolite,牛磺熊去氧胆酸,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis; ERK; P450; Caspase; Endogenous Metabolite	Apoptosis; MAPK; Metabolism; Proteases/Proteasome
	Tauroursodeoxycholate (UR 906)，又称 ursodoxicoltaurine，是一种高度亲水性的三级胆汁酸，在人体内以低浓度产生。Tauroursodeoxycholate 是 ursodeoxycholic acid 更亲水的形式，而 ursodeoxycholic acid 是人类体内自然产生的更丰富的胆汁酸。Tauroursodeoxycholate 正在研究用于几种疾病，如原发性胆汁性肝硬化(PBC)、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤滞和肌萎缩性侧索硬化症。
TCS2170	2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP	ERK; NF-κB; Tyrosinase	MAPK; NF-κB; Proteases/Proteasome
	2,5-Dihydroxyacetophenone (Quinacetophenone) 是从熟地黄中分离出的一种天然产物，通过阻断 ERK1/2和 NF-κB 信号通路，抑制活化巨噬细胞中炎症介质的产生。
T79951	Piperkadsin A	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Piperkadsin A作为一种ROS抑制剂，能够有效地抑制PMA诱导的人多形核中性粒细胞中ROS的生成，其IC50值为4.3 μM。
T10383	Asatone	NF-κB	NF-κB
	Asatone 是一种从细辛中分离到的活性成分，通过活化 NF-κB 及下调 p-MAPK (ERK，JNK 和 p38) 通路起作用，具有抗炎作用。
TN4114	Gardenin A	ERK; LDL; MAPK; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; Tyrosine Kinase/Adaptors
	Gardenin A 通过激活 MAPK/ERK、PKC 和 PKA 表现出神经营养作用。 Gardenin A 具有抗抑郁、抗惊厥和抗焦虑作用。
TN1786	Isomerazin Isomeranzin,异橙皮内酯	ERK; NF-κB; AChE	MAPK; Neuroscience; NF-κB
	Isomerazin (Isomeranzin) 是一种香豆素类化合物，分离于 Poncirus trifoliateRaf 中，具有胆碱酯酶抑制作用。
T2845	Imperatorin Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen	TRP/TRPV Channel; AChR; AChE; NOD	Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB
	Imperatorin (8-Isopentenyloxypsoralene) 是NO synthesis 和BChE 的抑制剂，IC50分别为 9.2 μmol 和 31.4 μmol。它也是TRPV1的微弱激动剂，EC50为 12.6±3.2 μM。
T5S0168	Atractylenolide II 2-Atractylenolide,Asterolide,苍术内酯II	Apoptosis; ERK; p38 MAPK; Akt; STAT	Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Atractylenolide II (2-Atractylenolide) 是一种从白术干燥根茎分离的倍半萜类天然产物，具有抗增殖活性。
T6S0923	Hypericin Hypericine,金丝桃素,Cyclosan	Apoptosis; Antiviral; Influenza Virus; Tyrosine Kinases; Antibacterial; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Hypericin (Cyclosan) 是贯叶连翘的提取物，有抗菌、抗病毒、抗肿瘤和抗抑郁作用。
T3908	10-Gingerol 10-姜酚	Apoptosis	Apoptosis
	10-Gingerol 是一种姜根脂的主要刺激性成分，具有抗炎、抗氧化和抗增殖作用，能够抑制 MDA-MB-231 肿瘤细胞的增殖(IC50:12.1 μM)。
T6S1740	Nardosinone 苷松新酮,甘松新酮	Others	Others
	Nardosinone 是一个 dbcAMP 和 staurosporine 的神经生成作用增强剂，分离自Nardostachys chinensis 中。Nardosinone 可能成为一种有用的药理学工具，不仅可用于研究神经生长因子 (NGF) 的作用机理，而且可用于研究神经毒性物质的作用机理。
TN1880	Lucidenic acid B Lucidenicacid B	Apoptosis; Caspase	Apoptosis; Proteases/Proteasome
	Lucidenic acid B (Lucidenicacid B) 是从灵芝中提取得到的天然化合物，可诱导caspase-9 和 caspase-3 的活化和 PARP 的裂解，可通过线粒体介导诱导人白血病细胞凋亡。 Lucidenic acid B通过灭活MAPK / ERK信号转导途径和降低NF-kappaB和AP-1的结合活性来抑制PMA诱导的人肝癌细胞侵袭。。Lucidenic acid B 对细胞周期和坏死细胞没有影响。
T3123	Allicin	ERK; IL Receptor; Others; IκB/IKK; p38 MAPK; TNF; ROS; Caspase; Antifection	Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; NF-κB; Others; Proteases/Proteasome
	Allicin 具有抗氧化、杀菌、抗癌、抗炎活性，对肠上皮细胞具有抑制性免疫调节作用。 Allicin 能显着抑制胰岛素诱导的血管平滑肌细胞的增殖和迁移，这可能与抑制 ERK 信号通路的激活有关。 Allicin 有利于降低高胆固醇血症大鼠的血液胆固醇、甘油三酯水平和收缩压，它可能有益于影响动脉粥样硬化的两个危险因素——高脂血症和高血压。
TN2244	Sulfuretin 硫黄菊素	NF-κB; Autophagy	Autophagy; NF-κB
	Sulfuretin 是竞争性单酚酶和二酚酶活性抑制剂，IC50=13.64 μM。它通过抑制NF-κB 通路来抑制炎症反应。它可用于过敏性气道炎症的研究。它减少氧化应激、血小板聚集和诱变。
T5S0890	Oleandrin Neriostene,Folinerin,Foliandrin,欧夹竹桃苷	Apoptosis; ATPase; Potassium Channel; Sodium Channel	Apoptosis; Membrane transporter/Ion channel
	Oleandrin (Folinerin) 是夹竹桃属中的一种类固醇，可抑制Na+/K+-ATPase 活性，IC50为 620 nM。
T3822	Bellidifolin Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Bellidifolin (Bellidifoline) 是从獐牙菜的茎中提取的一种呫吨酮，它能作为病毒蛋白 R 的抑制剂，具有保肝、降血糖、抗炎、抗氧化、抗肿瘤作用。
TN1557	Decursinol angelate	ERK; VEGFR; PKC; JNK	Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors
	Decursinol angelate 是从朝鲜当归根部分离得到的一种天然产物，是 PKC 激酶的激活剂，有细胞毒性，抗肿瘤和抗炎活性。
TN5888	Toddaculin	Others	Others
	Toddaculin 是一种天然香豆素，抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡，具有抗炎活性。
T4518	Licochalcone D	ERK; NF-κB	MAPK; NF-κB
	Licochalcone D 是一种 NF-κB p65的有效抑制剂，是一种存在于 Glycyrrhiza inflate 中的黄酮类化合物，具有抗氧化、抗炎、抗癌等作用。
T3S2344	β,β-Dimethylacrylshikonin β,β-二甲基丙烯酰紫草素,Dimethylacrylshikonin,β, β-Dimethylacrylshikonin	ERK; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; MAPK; Metabolism
	β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) 是一种萘醌衍生物，从 Arnebia nobilis 中提取得到。它利用 PI3K 通路诱导 eNOS、VEGF 和 HIF-1α 的表达，促进血管生成，具有抗肿瘤活性。
T7472	7-Hydroxyflavone 7-羟基黄酮,7羟基黄酮	P450	Metabolism
	7-Hydroxyflavone 是一种黄酮类化合物，从M. indica 中分离得到，具有抗炎活性。它利用 ERK/Nrf2/HO-1 通路保护肾细胞，使其免受尼古丁诱导的细胞毒性。
T6S0525	Farrerol	ERK; p38 MAPK; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Farrerol 是一种杜鹃花的生物活性成分，具有抗氧化、抗肿瘤、抗炎、神经保护和肝保护等多种功能。
T3824	Jaceosidin	Apoptosis; BCL; COX; UGT	Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
	Jaceosidin 是从毛莲蒿中得到的一种黄酮类天然产物，可激活Bax，下调 Mcl-1 和 c-FLIP 的表达，诱导癌细胞凋亡。它能够降低炎性因子水平，激活 NF-κB，抑制COX-2的表达，具有抗癌和抗炎作用。
T4S0878	Prunetin 樱黄素,Prunusetin	ERK; Dehydrogenase; NF-κB	MAPK; Metabolism; NF-κB
	Prunetin (Prunusetin) 是一种O-甲基化异黄酮，具有抗炎的作用。它是人醛脱氢酶的有效抑制剂。
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮	Others	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone 是来自蜜柑皮中的黄酮，具有抗肿瘤起始活性和抗神经炎症作用。它能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子表达，降低 C6 细胞磷酸二酯酶活性。它能抑制胶原酶的活性，增加人真皮成纤维细胞新生细胞中 I 型前胶原含量。
TN1222	26-Deoxyactein 27-Deoxyactein,脱氧升麻烃,23-epi-26-Deoxyactein,27-脱氧升麻亭	NOS; CDK; NO Synthase	Cell Cycle/Checkpoint; Immunology/Inflammation
	23-epi-26-Deoxyactein (27-Deoxyactein) 是一种黑升麻中的主要成分，能够阻止 TCDD 诱导的成骨细胞的损伤。它对 AhR，CYP1A1 和 ERK 的水平升高具有抑制作用。
T2940	6-Hydroxyflavone 6-羟基黄酮,6-HF	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	6-Hydroxyflavone (6-HF) 是天然存在的黄酮化合物，具有抗炎作用。它对牛血红蛋白糖基化具有抑制作用。它能激活 AKT、ERK 1/2、JNK 信号通路，有效促进成骨细胞分化。它能抑制 LPS 诱导的 NO 的产生。
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天然产物

Cat.No: TN2346

Target: ERK, AMPK, STAT

Cat.No: T6S0655

Target: ERK

Tenuifoliside A

Cat.No: T3856

Target: ERK, Others

Cat.No: T3857

Synonym: 木兰脂素,(+)-Magnolin,木兰苷

Target: ERK

Cat.No: T5S1982

Synonym: Periplocoside,杠柳毒苷

Target: Apoptosis, Others

Cat.No: T3844

Synonym: 三角叶薯蓣皂苷

Target: ERK, Others, Akt, Endogenous Metabolite

Epieriocalyxin A

Cat.No: TN3967

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Cat.No: T6947

Synonym: PPLGM,荜茇酰胺,Piplartine

Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy

Cat.No: TL0016

Synonym: 油菜

Target: Apoptosis, ERK, EGFR, NF-κB

Asperulosidic acid

Cat.No: TN1410

Synonym: ASPA,车叶草苷酸

Target: ERK, NF-κB

Cat.No: T3876

Synonym: 龙血素B,龙血素 B

Target: PAI-1, ERK, Potassium Channel, JNK

Cat.No: TN1721

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Cat.No: TMS2181

Synonym: (E)-Zeatin,玉米素

Target: ERK, MEK, Endogenous Metabolite

Cat.No: T6S0619

Synonym: 3-O-Acetyltumulosic acid,茯苓酸

Target: ERK, Akt

Cat.No: T5727

Synonym: 咖啡醇,咖啡油醇

Target: ERK, NF-κB, COX, PGE Synthase

Nitidine chloride

Cat.No: T5S0761

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Cat.No: T3001

Synonym: 和厚朴酚,NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Astragaloside IV

Cat.No: T2973

Synonym: AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

Cat.No: T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Cat.No: T13265

Synonym: 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Cat.No: T6S0117

Synonym: Fenicularin,扁蓄苷

Target: ERK

Cat.No: T5S1058

Synonym: 雷公藤内酯酮,PG 492,NSC 165677

Target: Apoptosis, Wnt/beta-catenin, Autophagy

Cat.No: TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan,黄芪紫檀烷,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷

Target: ERK, PDGFR

Tauroursodeoxycholate

Cat.No: T2532

Synonym: Taurolite,牛磺熊去氧胆酸,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

2,5-Dihydroxyacetophenone

Cat.No: TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP

Target: ERK, NF-κB, Tyrosinase

Cat.No: T79951

Target: Reactive Oxygen Species

Cat.No: T10383

Target: NF-κB

Cat.No: TN4114

Target: ERK, LDL, MAPK, PKA, PKC

Cat.No: TN1786

Synonym: Isomeranzin,异橙皮内酯

Target: ERK, NF-κB, AChE

Cat.No: T2845

Synonym: Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen

Target: TRP/TRPV Channel, AChR, AChE, NOD

Atractylenolide II

Cat.No: T5S0168

Synonym: 2-Atractylenolide,Asterolide,苍术内酯II

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

Cat.No: T6S0923

Synonym: Hypericine,金丝桃素,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Cat.No: T3908

Synonym: 10-姜酚

Target: Apoptosis

Cat.No: T6S1740

Synonym: 苷松新酮,甘松新酮

Target: Others

Lucidenic acid B

Cat.No: TN1880

Synonym: Lucidenicacid B

Target: Apoptosis, Caspase

Cat.No: T3123

Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection

Cat.No: TN2244

Synonym: 硫黄菊素

Target: NF-κB, Autophagy

Cat.No: T5S0890

Synonym: Neriostene,Folinerin,Foliandrin,欧夹竹桃苷

Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel

Cat.No: T3822

Synonym: Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮

Target: Others, HIV Protease

Decursinol angelate

Cat.No: TN1557

Target: ERK, VEGFR, PKC, JNK

Cat.No: TN5888

Target: Others

Cat.No: T4518

Target: ERK, NF-κB

β,β-Dimethylacrylshikonin

Cat.No: T3S2344

Synonym: β,β-二甲基丙烯酰紫草素,Dimethylacrylshikonin,β, β-Dimethylacrylshikonin

Target: ERK, HIF/HIF Prolyl-Hydroxylase

7-Hydroxyflavone

Cat.No: T7472

Synonym: 7-羟基黄酮,7羟基黄酮

Target: P450

Cat.No: T6S0525

Target: ERK, p38 MAPK, Akt

Cat.No: T3824

Target: Apoptosis, BCL, COX, UGT

Cat.No: T4S0878

Synonym: 樱黄素,Prunusetin

Target: ERK, Dehydrogenase, NF-κB

3,5,6,7,8,3',4'-Heptemthoxyflavone

Cat.No: TN1088

Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮

Target: Others

Cat.No: TN1222

Synonym: 27-Deoxyactein,脱氧升麻烃,23-epi-26-Deoxyactein,27-脱氧升麻亭

Target: NOS, CDK, NO Synthase

6-Hydroxyflavone

Cat.No: T2940

Synonym: 6-羟基黄酮,6-HF

Target: GABA Receptor

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04539	ERK2 Protein, Human, Recombinant (GST) ERT1,ERK,PRKM1,ERK-2,p41,p41mapk,PRKM2,	Human	Baculovirus Insect Cells
	ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 67 kDa and the accession number is P28482-1.
TMPY-04571	ERK2 Protein, Mouse, Recombinant (His & GST) PRKM2,C78273,mitogen-activated protein kinase 1,AU018647,p41...	Mouse	Baculovirus Insect Cells
	ERK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.1 kDa and the accession number is P63085.
TMPY-01067	EphB2 Protein, Human, Recombinant (His) EPH receptor B2,DRT,EK5,PCBC,ERK,CAPB,EPHT3,Hek5,Ty...	Human	HEK293 Cells
	EphB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P29323-2.
TMPY-04386	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,ERK	Human	Baculovirus Insect Cells
	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPY-03621	EphB2 Protein, Mouse, Recombinant (hFc) Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,P...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPY-04216	EphB2 Protein, Mouse, Recombinant (His) Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH receptor B...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
TMPY-00784	EphB2 Protein, Human, Recombinant (His & hFc) Tyro5,EPHT3,DRT,EK5,PCBC,ERK,EPH receptor B2,Hek5,C...	Human	HEK293 Cells
	EphB2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 86 kDa and the accession number is P29323-2.
TMPY-04430	p38 gamma/MAPK12 Protein, Human, Recombinant mitogen-activated protein kinase 12,SAPK-3,P38 γ/MAPK12,SAPK...	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
TMPY-04429	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) ERK3,SAPK3,PRKM12,ERK6,P38γ,P38GAMMA,mitog...	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
TMPK-00563	EPHB2 Protein, Cynomolgus, Recombinant (His) DRT,Nuk,Sek3,TYRO5,EPHT3,HEK5,EphB2,Qek2,PCBC,EPHT3MGC87492,...	Cynomolgus	HEK293 Cells
	EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) TCGF,Aldesleukin,T-Cell Growth Factor,IL-2,Interleukin-2,IL2	Human	HEK293 Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST) MKK4,MEK4,PRKMK4,Sek1,JNKK1,Serk1,mitogen-activated...	Mouse	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is a protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase that is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / ...
TMPJ-00376	IL-17RD Protein, Human, Recombinant (hFc) IL17Rhom,IL17RD,IL-17RD,IL-17 RD,IL17RLM,SEF,interleukin 17 ...	Human	HEK293 Cells
	Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. It may inhibit FGF-induced FGFR1 tyrosine phosphorylation, regulate the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK By similarity, and mediate JNK activation ...
TMPY-04425	PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST) PRAK,MAPKAP-K5,MK-5,mitogen-activated protein kinase-activat...	Human	Baculovirus Insect Cells
	MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK). It is widely distributed. MAPKAPK5 can be phosphorylated by an extracellular-regulated kinase (ERK), and p38 kinase but not by c-jun N-terminal kinase (JNK)in vitro. Recombinant GST-MAPKAPK5 protein can phosphorylate a peptide derived from the regulator...
TMPY-04544	MEK2 Protein, Human, Recombinant (GST) mitogen-activated protein kinase kinase 2,FLJ26075,MKK2,CFC4...	Human	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion ...
TMPK-00136	ULBP-2 Protein, Human, Recombinant (His & Avi) ALCAN-α,RAET1L,NKG2D ligand 2,ALCAN-alpha,N2DL2,ULBP-2/5/6,R...	Human	HEK293 Cells
	ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
TMPH-01692	MAPK3 Protein, Human, Recombinant (His)	Human	E. coli
	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, c...
TMPK-00820	AREG Protein, Human, Recombinant (hFc) SDGF,AR,MGC13647,AREGB,CRDGF,Amphiregulin,AREG	Human	HEK293 Cells
	Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF‑κB signalling pathway in pancreatic cancer cells.
TMPH-03265	CMKLR2 Protein, Rat, Recombinant (His) Chemerin chemokine-like receptor 2,Gpr1,Chemokine-like recep...	Rat	E. coli
	Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway.
TMPH-01609	LGI1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
TMPK-00723	RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) CD265,Rank,FEO,ODFR,NF-KB,OSTS,TNFRSF11A,OPTB7,NFKB,TRANCER,...	Mouse	HEK293 Cells
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 47.0 kDa and the acce...
TMPH-03368	SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway. SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.2 kDa and the accessio...
TMPY-04378	MAPKAPK3 Protein, Human, Recombinant (GST) mitogen-activated protein kinase-activated protein kinase 3,...	Human	Baculovirus Insect Cells
	The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identified and serve as substrates for the ERK and p38 MAP kinases. Mitogen-activated protein (MAP) kinase-activated protein kinase 3, also known as MAPKAPK-3 and 3pK, is a member of the Ser/Thr protein kinase family. It is widely expressed in hu...
TMPY-04374	MST4 Protein, Human, Recombinant (GST) serine/threonine protein kinase 26,MST4,MASK	Human	Baculovirus Insect Cells
	MST4, also known as mammalian STE2-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste2-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains a C-terminal regulatory domain and an N-terminal kinase domain, both of which are required for full activation of the kinase. MST4 is highly expressed in the placenta, thymus, and peripheral blood leukocytes. MST4 specifically activates ERK but not JNK or p38 MAPK in transiently ...
TMPK-00351	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) NF-KB,ODFR,PDB2,Rank,OSTS,NFKB,OPTB7,TNFRSF11A,LOH18CR1,CD26...	Human	HEK293 Cells
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.85 kDa ...
TMPK-00925	Noggin/NOG Protein, Mouse, Recombinant NOG,SYM1,SYNS1,Noggin	Mouse	HEK293 Cells
	Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG...
TMPK-00926	Noggin/NOG Protein, Mouse, Recombinant (His & Flag) SYNS1,NOG,SYM1,Noggin	Mouse	HEK293 Cells
	Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG...
TMPJ-01125	PEA15 Protein, Human, Recombinant 15 kDa Phosphoprotein Enriched in Astrocytes,PEA15,PED,Astro...	Human	E. coli
	Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm...
TMPJ-00796	Serpin E2 Protein, Human, Recombinant (His) PN-1,PI-7,Protease nexin 1,PI7,GDN,Peptidase inhibitor 7,Ser...	Human	HEK293 Cells
	Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal pancreas and chronic pancreatitis tissue. In contrast, it was strongly over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples. Serpin E2 promotes neurite extension by inhibiting thrombin. It also can bind heparin. It has been shown tha...
TMPY-04466	STK40 Protein, Human, Recombinant (His & GST) SHIK,SgK495,serine/threonine kinase 40	Human	Baculovirus Insect Cells
	STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to activate the Erk/MAPK pathway and induce extraembryonic-endoderm (ExEn) differentiation in mouse ESCs. Interestingly, cells overexpressing Stk40 exclusively contribute to the ExEn layer of chimeric embryos when injected into host blastocysts. In contrast, deletion of Stk40 in ES...
TMPY-04410	MAP4K5 Protein, Human, Recombinant (His & GST) KHS,GCKR,MAPKKKK5,mitogen-activated protein kinase kinase ki...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE2, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, and MAP4K5, is a cytoplasm protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. MAP4K5 is ubiquitously expressed in all tissues examined, with high levels in the ovary, testis, and prostate. It contains one CNH domain and one protein kinase domain. MAP4K5 is highly similar to yeast SPS...
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP) MKP6,MKP-L,dual specificity phosphatase 14	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosphotyrosine and phosphoserine / phosphothreonine residues in substrates. Unlike many other DUSPs, DUSP14 only contains a catalytic domain within the C-terminal region. In signal transduction, DUSP14 has been considered as negative regulator of the mitogen-activated protein kinase (...
TMPJ-00674	RANK/TNFRSF11A Protein, Mouse, Recombinant (His) Receptor activator of NF-KB,TNFRSF11A,Osteoclast differentia...	Mouse	HEK293 Cells
	Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, br...
TMPY-04389	MAP3K8 Protein, Human, Recombinant (GST) TPL2,MEKK8,EST,ESTF,COT,Tpl-2,c-COT,AURA2,mitogen-activated ...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase 8, also known as Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2 and MAP3K8, is a cytoplasm protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K8 is expressed in several normal tissues and human tumor-derived cell lines. Isoform 1 of MAP3K8 is activated specifically during the S and G2/M phases of the...
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated Polymorphic epithelial mucin,KL-6,Cancer antigen 15-3,PEMT,P...	Human	HEK293 Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1 exclusively located in the apical domain of the plasma membrane ...
TMPY-04412	Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST) mitogen-activated protein kinase kinase kinase kinase 2,GCK,...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein, and MAP4K2, is cytoplasm and peripheral membrane protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. MAP4K2 contains one CNH domain and one protein kinase domain. Although this kinase is found in many tissues, its express...
TMPY-02519	BLVRB Protein, Human, Recombinant (His) HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U1	Human	E. coli
	Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i...
TMPY-04084	ANGPTL1 Protein, Canine, Recombinant (hFc) angiopoietin-like 1	Canine	HEK293 Cells
	Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an important role in the pathogenesis of hepatocellular carcinoma (HCC).The downregulation of the angiopoietin-like protein ANGPTL1 is associated with vascular invasion, tumor thrombus, metastasis, and poor prognosis in HCC. Ectopic expression of ANGPTL1 in HCC cells effectively decre...
TMPY-04455	PKC iota Protein, Human, Recombinant (GST) PKCI,nPKC-iota,protein kinase C, ι,DXS1179E,nPKC-ι,protein k...	Human	Baculovirus Insect Cells
	Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and PKC subfamily. PRKCI contains one AGC-kinase C-terminal domain, one OPR domain, one phorbol-ester/DAG-type zinc finger and one protein kinase domain. PRKCI is predominantly expressed in lung and brain, but also expressed at lower levels in many tissues includ...
TMPY-04467	NME1 Protein, Human, Recombinant (His) NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,NM23-H1,N...	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...
TMPJ-00060	IL-25/IL17E Protein, Human, Recombinant (His) 白细胞介素,IL17E,白介素,IL-17E,IL-25,IL25,Interleukin-25,Interleukin...	Human	HEK293 Cells
	Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator...
TMPY-02191	BLNK Protein, Human, Recombinant (His) BLNK-S,bca,SLP-65,B-cell linker,LY57,SLP65,AGM4,BASH	Human	HEK293 Cells
	B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 and BLNK, is a cytoplasm and cell membrane protein which contains oneSH2 domain. BLNK is expressed in B-cell lineage and fibroblast cell lines. Highest levels of expression is in the spleen, with lower levels in the liver, kidney, pancreas, small inte...
TMPY-04391	Lyn Protein, Human, Recombinant (GST) JTK8,LYN proto-oncogene, Src family tyrosine kinase,p56Lyn,p...	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between prolif...

重组蛋白

ERK2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04539

Species: Human

Expression System: Baculovirus Insect Cells

ERK2 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04571

Species: Mouse

Expression System: Baculovirus Insect Cells

EphB2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01067

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

Cat.No: TMPY-04386

Species: Human

Expression System: Baculovirus Insect Cells

EphB2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03621

Species: Mouse

Expression System: HEK293 Cells

EphB2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04216

Species: Mouse

Expression System: HEK293 Cells

EphB2 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00784

Species: Human

Expression System: HEK293 Cells

p38 gamma/MAPK12 Protein, Human, Recombinant

Cat.No: TMPY-04430

Species: Human

Expression System: Baculovirus Insect Cells

p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04429

Species: Human

Expression System: Baculovirus Insect Cells

EPHB2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00563

Species: Cynomolgus

Expression System: HEK293 Cells

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

Cat.No: TMPJ-01464

Species: Human

Expression System: HEK293 Cells

MKK4 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04572

Species: Mouse

Expression System: Baculovirus Insect Cells

IL-17RD Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00376

Species: Human

Expression System: HEK293 Cells

PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04425

Species: Human

Expression System: Baculovirus Insect Cells

MEK2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04544

Species: Human

Expression System: Baculovirus Insect Cells

ULBP-2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00136

Species: Human

Expression System: HEK293 Cells

MAPK3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01692

Species: Human

Expression System: E. coli

AREG Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00820

Species: Human

Expression System: HEK293 Cells

CMKLR2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03265

Species: Rat

Expression System: E. coli

LGI1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01609

Species: Human

Expression System: E. coli

RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00723

Species: Mouse

Expression System: HEK293 Cells

SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03368

Species: Rat

Expression System: E. coli

MAPKAPK3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04378

Species: Human

Expression System: Baculovirus Insect Cells

MST4 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04374

Species: Human

Expression System: Baculovirus Insect Cells

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)

Cat.No: TMPK-00351

Species: Human

Expression System: HEK293 Cells

Noggin/NOG Protein, Mouse, Recombinant

Cat.No: TMPK-00925

Species: Mouse

Expression System: HEK293 Cells

Noggin/NOG Protein, Mouse, Recombinant (His & Flag)

Cat.No: TMPK-00926

Species: Mouse

Expression System: HEK293 Cells

PEA15 Protein, Human, Recombinant

Cat.No: TMPJ-01125

Species: Human

Expression System: E. coli

Serpin E2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00796

Species: Human

Expression System: HEK293 Cells

STK40 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04466

Species: Human

Expression System: Baculovirus Insect Cells

MAP4K5 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04410

Species: Human

Expression System: Baculovirus Insect Cells

DUSP14 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPY-02595

Species: Human

Expression System: E. coli

RANK/TNFRSF11A Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00674

Species: Mouse

Expression System: HEK293 Cells

MAP3K8 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04389

Species: Human

Expression System: Baculovirus Insect Cells

Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated

Cat.No: TMPJ-00155

Species: Human

Expression System: HEK293 Cells

Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04412

Species: Human

Expression System: Baculovirus Insect Cells

BLVRB Protein, Human, Recombinant (His)

Cat.No: TMPY-02519

Species: Human

Expression System: E. coli

ANGPTL1 Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-04084

Species: Canine

Expression System: HEK293 Cells

PKC iota Protein, Human, Recombinant (GST)

Cat.No: TMPY-04455

Species: Human

Expression System: Baculovirus Insect Cells

NME1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04467

Species: Human

Expression System: E. coli

IL-25/IL17E Protein, Human, Recombinant (His)

Cat.No: TMPJ-00060

Species: Human

Expression System: HEK293 Cells

BLNK Protein, Human, Recombinant (His)

Cat.No: TMPY-02191

Species: Human

Expression System: HEK293 Cells

Lyn Protein, Human, Recombinant (GST)

Cat.No: TMPY-04391

Species: Human

Expression System: Baculovirus Insect Cells

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