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Targets Recommended: CaMK LTR

427

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T7841 MK 571

MK-571钠盐,L660711,L-660711,MK-571

LTR Immunology/Inflammation
MK 571 (L660711) 是一种具有口服活性的 CysLT1 受体拮抗剂。
T33422 MK-0873

MK 0873,MK0873

PDE Metabolism
MK-0873 是一种新型且有效的选择性磷酸二酯酶 4 (PDE4) 抑制剂。
T33414 MK 0434

MK0434,MK434,MK 434,MK-0434,MK-434

MK 0434 is a steroid 5α-reductase inhibitor and hormone antagonist associated with a significant reduction in DHT.
T5187 MK-3903

MK 3903

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
MK-3903 是一种有选择性 AMP 激活的蛋白激酶 (AMPK) 激活剂,其EC50值为 8 nM。
T24480 MK-8325

MK 8325,MK8325

HCV Protease Microbiology/Virology; Proteases/Proteasome
MK-8325是一种有效且可口服的HCV NS5A 抑制剂,对多种基因型具有复制活性。MK-8325在体外和体内试验显示生物利用度且具有良好的总体ADME 特征。
T3722 MK-1064

Urokinase inhibitor 1,MK 1064

OX Receptor GPCR/G Protein; Neuroscience
MK-1064 (Urokinase inhibitor 1) 是一种选择性食欲素 2 (2-SORA)受体拮抗剂,可用于失眠患者的研究。
T28059 MK-4409

MK4409,MK 4409

MK-4409, a potent and selective fatty acid amide hydrolase (FAAH) inhibitor, is being investigated for the treatment of inflammatory and neuropathic pain.
T1952 MK-2206 dihydrochloride

MK-2206 2HCl

Apoptosis; Akt; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
MK-2206 dihydrochloride (MK-2206 2HCl) 是一种变构 Akt 抑制剂,抑制 Akt1、Akt2 和 Akt3 (IC50=8/12/65 nM),具有口服活性的、高效选择性。MK-2206 dihydrochloride 具有抗肿瘤活性。
T20950 MK-8245 analog

MK-8245-analog,MK 8245 analog

Others Others
MK-8245 analog 是 MK-8245 的类似物,MK-8245 是一种肝脏靶向的硬脂酰辅酶 A 去饱和酶 (SCD) 抑制剂。它可用于治疗血脂异常和糖尿病。
T68103L Mk-6186 HCl

Mk-6186 HCl(1034474-19-5 Free base)

HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
MK-6186 HCl,一种新型非核苷类逆转录酶抑制剂,具有抗病毒活性,可用于研究HIV。
T12070 MK-8719

Others Others
MK-8719 是高效的O-GlcNAcase 选择性抑制剂 (hOGA 的Ki=为 7.9 nM),中枢神经系统渗透性能良好。
T33421 MK-0686

MK0686

Bradykinin Receptor GPCR/G Protein
MK-0686 是一种可口服的缓激肽 B1 受体拮抗剂,具有潜在的抗炎活性。
T16088 MK-0608

HCV Protease Microbiology/Virology; Proteases/Proteasome
MK-0608 是一种可口服的体外 HCV 复制抑制剂。在亚基因组复制子测定中,EC50值为 0.3 μM,EC90值为 1.3 μM。
TQ0286 MK-0557

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
MK-0557 是神经肽 Y5 受体的选择性口服拮抗剂,Ki 值为1.6 nM。
T16089 MK-0674

Cysteine Protease Proteases/Proteasome
MK-0674 是一种可口服且具有选择性和高效性的 cathepsin K 抑制剂(IC50:0.4 nM),抑制 Cat B、Cat F、Cat L 和 Cat S,可用于和代谢相关的疾病。
T16090 MK-0773

PF-05314882

Androgen Receptor Endocrinology/Hormones
MK-0773 (PF-05314882) 是一种选择性雄激素受体调节剂,能与 AR 结合(IC50:6.6 nM),可用于研究内分泌异常引起的疾病。
T22986 MK 1903

GPR Endocrinology/Hormones; GPCR/G Protein
MK 1903 是一种有效的、具有选择性的羟基羧酸受体2 (HCA2) 的完全激动剂。HCA2也叫做G 蛋白偶联受体109A(GPR109A) 。MK 1903在使用表达人受体(ECso-12.9 nM)的 CHO 细胞进行的均匀时间分辨荧光(htf)测定中,它减少了福斯克林诱导的 cAMP 的产生。
T16090L MK-0773 FA

MK-0773 FA (606101-58-0 Free base)

Androgen Receptor Endocrinology/Hormones
MK-0773 FA (MK-0773 FA (606101-58-0 Free base)) 是一种选择性雄激素受体调节剂 ,对 AR 的 IC50 值为 6.6 nM,可用于预防和治疗与癌症相关的肌肉萎缩。
T12054L MK-0249 FA

MK-0249 FA(862309-06-6 Free base)

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
MK-0249 FA 是一种具有口服活性、选择性和高效性的组胺 H3 反向激动剂,可用于研究成人注意力缺陷、多动症神经分裂和认知障碍。
TQ0108 MK-6892

GPR Endocrinology/Hormones; GPCR/G Protein
MK-6892 是烟酸受体GPR109A 选择性激动剂。它作用于人 GPR109A 的Ki=4 nM,EC50=16 nM。
T1913 MK-3697

OX Receptor GPCR/G Protein; Neuroscience
MK3697是OX2受体的一种高效选择性拮抗剂,Ki 值为0.95nM。
TQ0219 MK-8033

c-Met/HGFR Tyrosine Kinase/Adaptors
MK-8033 是一种新型ATP 竞争性c-Met/Ron 双重抑制剂,对野生型c-Met 的IC50=1 nM,对c-Met N1100Y 的IC50=2.0 nM。
T6094 MK-2461

MK2461

c-Met/HGFR Tyrosine Kinase/Adaptors
MK-2461 是 ATP 竞争性的 c-Met 抑制剂, 平均 IC50 值为 2.5 nM。
T6891 MK-4101

Apoptosis; Hedgehog/Smoothened; Smo Apoptosis; GPCR/G Protein; Stem Cells
MK-4101 是一种 SMO 拮抗剂 ,对 293 细胞的 IC50为 1.1 µM。它也是一种 hedgehog 信号通路的有效抑制剂 ,对小鼠细胞和KYSE180 食管癌细胞的IC50分别为 1.5 µM 和 1 µM。它能抗肿瘤,抑制肿瘤细胞增殖并诱导细胞凋亡。
T2625 MK-0752

Beta Amyloid; Gamma-secretase Neuroscience; Proteases/Proteasome; Stem Cells
MK0752 是一种高效的、特异性的、可穿过血脑屏障的、口服活性的 γ-分泌酶(γ-secretase)抑制剂,对人 SH-SY5Y 细胞 Aβ40 呈剂量依赖性降低(IC50=5 nM)。它能够降低体内新生的中枢神经系统 Aβ。
T33429 MK-2295

TRP/TRPV Channel Membrane transporter/Ion channel
MK-2295 是一种有效的 TRPV1 拮抗剂。 MK-2295 可用于治疗慢性疼痛的研究。
T16094 MK-3328

Others Others
MK-3328 是对β-淀粉样蛋白 (β-Amyloid)具有很高的亲和力(IC50 为 10.5 nM),是一种可作为临床评估β-淀粉样斑块负荷的候选 PET 配体。MK-3328是治疗阿尔茨海默病的潜在药物。
T4106 MK-8617

MK8617

HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism
MK-8617 是一种口服具有活力的低氧诱导因子脯氨酰羟化酶 1-3 (HIF PHD1-3) 泛抑制剂,对于PHD2的IC50=1 nM。
T2471 MK-8745

Apoptosis; Aurora Kinase Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
MK8745是一种极光激酶抑制剂,IC50值为0.6 nM。
T2650 MK-8245

Dehydrogenase; Stearoyl-CoA Desaturase (SCD) Metabolism
MK8245 是肝靶向的硬脂酰 -CoA 去饱和酶(SCD)抑制剂,对人 SCD1 和鼠 SCD1 的IC50值分别为 1 nM 和 3 nM,具有抗糖尿病和抗血脂异常的作用。
T15942 MK-7622

M1 receptor modulator

AChR Neuroscience
MK-7622 (M1 receptor modulator) 是毒蕈碱 M1 受体阳性变构的调节剂。
T6068 MK-5108

VX-689,MK5108

Aurora Kinase; Autophagy Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic
MK-5108 (VX-689) 是一种高效且特异性的 Aurora-A 激酶抑制剂,IC50 值为 0.064 nM。
T12069 MK-8353

SCH900353

ERK MAPK
MK-8353 (SCH900353) 是口服有效的ERK1/2选择性抑制剂,IC50分别为 23.0 nM 和 8.8 nM。它显示出抗肿瘤活性。
T6893 MK-886

MK886,L 663536

Apoptosis; Leukotriene Receptor; COX; PPAR; FLAP Apoptosis; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
MK-886 (L 663536)是一种细胞可渗透的,具有口服活性的 FLAP (IC50为 30 nM) 和白三烯生物合成 (完整白细胞和人全血中的IC50分别为 3 nM 和 1.1μM) 的抑制剂。它也是一种非竞争性PPARα拮抗剂,可以诱导细胞凋亡。
T12056 MK-0941 free base

Glucokinase Metabolism
MK-0941 free base 是一种口服具有活力的葡糖激酶抑制剂,在葡萄糖浓度为 2.5 和 10 mM 的条件下,对重组人 glucokinase 的EC50值分别为 240 和 65 nM。它具有较强的降血糖特性,是研究 2 型糖尿病的候选药物。
T6352 (-)-Dizocilpine maleate

C13737,(-)-MK 801 (Maleate),(-)-MK 801马来酸,(-)-MK 801 Maleate

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) 是一种选择性且非竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂,Ki 为 211.7 nM。它是一种 Dizocilpine 的活性较低的 (-)-对映体,具有抗抑郁作用。
T3148 MK-571 sodium

L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid

Leukotriene Receptor; LTR GPCR/G Protein; Immunology/Inflammation
MK-571 sodium (L-660711 sodium salt) 是一种可口服的选择性白三烯 D4受体拮抗剂,在豚鼠和人肺膜的 Ki 分别为0.22 和 2.1 nM。
T2517 SCH900776

MK 8776,MK-8776

Chk; CDK Cell Cycle/Checkpoint
SCH900776 (MK-8776) 是一种靶向细胞周期检查点激酶 1(Chk1) 的抑制剂,IC50值为 3 nM。它比对 CDK2 和 Chk2 的选择性分别高 50 和 500 倍,具有潜在的放射增敏和化学增敏活性。
T16091 MK-0812 Succinate

Others; CCR Immunology/Inflammation; Microbiology/Virology; Others
MK-0812 Succinate 是一种选择性CCR2拮抗剂。
T5632 Suvecaltamide

MK-8998

Calcium Channel Membrane transporter/Ion channel; Metabolism
Suvecaltamide (MK-8998) 是一种选择性的 T 型钙通道抑制剂。
T22987 MK 212 hydrochloride

5-HT Receptor GPCR/G Protein; Neuroscience
MK 212 monohydrochloride 是一种5-HT1C/5-HT2激动剂。它具有中枢作用,可刺激大脑皮层中的磷酸肌醇水解。
T12058 MK2-IN-3 hydrate

MK-2 Inhibitor III

ERK; MAPK; MNK MAPK
MK2-IN-3 hydrate (MK-2 Inhibitor III) 是一种口服有活性的、ATP 竞争性的MAPKAP-K2 (MK-2)选择性抑制剂(IC50:0.85 nM)。
T4442 MK2-IN-1 hydrochloride

MK2 Inhibitor,MK 25

MAPK MAPK
MK2-IN-1 hydrochloride (MK 25) 是一种高效的选择性 MAPKAPK2(MK2)激酶抑制剂,其 IC50值为0.11uM。
T22988 MK-4827 Racemate

Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
MK-4827 Racemate (Niraparib Racemate) 是一种选择性 PARP1 和 PARP2 抑制剂,IC50 分别为 3.8 nM 和 2.1 nM,对 PARP3、V-PARP 和 Tank1 的选择性超过 330 倍。
T61933 MK-0159

CD38 Immunology/Inflammation
MK-0159 是一种可口服且具有高效性的 CD38 抑制剂,具有心肌损伤保护作,可用于研究心脏缺血和再灌注损伤。
T61859 MK-28

Antiviral; PERK Apoptosis; Immunology/Inflammation
MK-28 是一种具有选择性的 PERK 激动剂,可降低亨廷顿病模型的毒性并延长生存期。MK-28 对MK28胃癌细胞有显著的杀伤作用。
T68103 MK-6186

Reverse Transcriptase Microbiology/Virology
MK-6186 是一种新型非核苷类逆转录酶抑制剂,具有抗病毒活性,可用于研究病毒感染。
T68015 Ruzasvir

MK8408,MK-8408,MK 8408

HCV Protease Microbiology/Virology; Proteases/Proteasome
Ruzasvir (MK-8408) 是一种新型有效的丙型肝炎病毒NS5A的泛基因型抑制剂,具有抗病毒活性。
T15712 Laropiprant

MK-0524

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Laropiprant (MK-0524) 是 DP receptor 的选择性拮抗剂,Ki 为 0.57 nM,对 TP 受体的 Ki 为 2.95 nM。
T2077 Adavosertib

AZD1775,MK-1775,Adavosertib (MK-1775)

Wee1 Cell Cycle/Checkpoint
Adavosertib (MK-1775) 是一种Wee1抑制剂,IC50值为 5.2 nM。它阻碍了 G2 DNA 损伤检查点。

化合物

MK 571
Cat.No: T7841
Synonym: MK-571钠盐,L660711,L-660711,MK-571
Target: LTR
MK-0873
Cat.No: T33422
Synonym: MK 0873,MK0873
Target: PDE
MK 0434
Cat.No: T33414
Synonym: MK0434,MK434,MK 434,MK-0434,MK-434
Target:
MK-3903
Cat.No: T5187
Synonym: MK 3903
Target: AMPK
MK-8325
Cat.No: T24480
Synonym: MK 8325,MK8325
Target: HCV Protease
MK-1064
Cat.No: T3722
Synonym: Urokinase inhibitor 1,MK 1064
Target: OX Receptor
MK-4409
Cat.No: T28059
Synonym: MK4409,MK 4409
Target:
MK-2206 dihydrochloride
Cat.No: T1952
Synonym: MK-2206 2HCl
Target: Apoptosis, Akt, Autophagy
MK-8245 analog
Cat.No: T20950
Synonym: MK-8245-analog,MK 8245 analog
Target: Others
Mk-6186 HCl
Cat.No: T68103L
Synonym: Mk-6186 HCl(1034474-19-5 Free base)
Target: HIV Protease, Reverse Transcriptase
MK-8719
Cat.No: T12070
Synonym:
Target: Others
MK-0686
Cat.No: T33421
Synonym: MK0686
Target: Bradykinin Receptor
MK-0608
Cat.No: T16088
Synonym:
Target: HCV Protease
MK-0557
Cat.No: TQ0286
Synonym:
Target: Neuropeptide Y Receptor
MK-0674
Cat.No: T16089
Synonym:
Target: Cysteine Protease
MK-0773
Cat.No: T16090
Synonym: PF-05314882
Target: Androgen Receptor
MK 1903
Cat.No: T22986
Synonym:
Target: GPR
MK-0773 FA
Cat.No: T16090L
Synonym: MK-0773 FA (606101-58-0 Free base)
Target: Androgen Receptor
MK-0249 FA
Cat.No: T12054L
Synonym: MK-0249 FA(862309-06-6 Free base)
Target: Histamine Receptor
MK-6892
Cat.No: TQ0108
Synonym:
Target: GPR
MK-3697
Cat.No: T1913
Synonym:
Target: OX Receptor
MK-8033
Cat.No: TQ0219
Synonym:
Target: c-Met/HGFR
MK-2461
Cat.No: T6094
Synonym: MK2461
Target: c-Met/HGFR
MK-4101
Cat.No: T6891
Synonym:
Target: Apoptosis, Hedgehog/Smoothened, Smo
MK-0752
Cat.No: T2625
Synonym:
Target: Beta Amyloid, Gamma-secretase
MK-2295
Cat.No: T33429
Synonym:
Target: TRP/TRPV Channel
MK-3328
Cat.No: T16094
Synonym:
Target: Others
MK-8617
Cat.No: T4106
Synonym: MK8617
Target: HIF/HIF Prolyl-Hydroxylase
MK-8745
Cat.No: T2471
Synonym:
Target: Apoptosis, Aurora Kinase
MK-8245
Cat.No: T2650
Synonym:
Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)
MK-7622
Cat.No: T15942
Synonym: M1 receptor modulator
Target: AChR
MK-5108
Cat.No: T6068
Synonym: VX-689,MK5108
Target: Aurora Kinase, Autophagy
MK-8353
Cat.No: T12069
Synonym: SCH900353
Target: ERK
MK-886
Cat.No: T6893
Synonym: MK886,L 663536
Target: Apoptosis, Leukotriene Receptor, COX, PPAR, FLAP
MK-0941 free base
Cat.No: T12056
Synonym:
Target: Glucokinase
(-)-Dizocilpine maleate
Cat.No: T6352
Synonym: C13737,(-)-MK 801 (Maleate),(-)-MK 801马来酸,(-)-MK 801 Maleate
Target: NMDAR, iGluR
MK-571 sodium
Cat.No: T3148
Synonym: L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid
Target: Leukotriene Receptor, LTR
SCH900776
Cat.No: T2517
Synonym: MK 8776,MK-8776
Target: Chk, CDK
MK-0812 Succinate
Cat.No: T16091
Synonym:
Target: Others, CCR
Suvecaltamide
Cat.No: T5632
Synonym: MK-8998
Target: Calcium Channel
MK 212 hydrochloride
Cat.No: T22987
Synonym:
Target: 5-HT Receptor
MK2-IN-3 hydrate
Cat.No: T12058
Synonym: MK-2 Inhibitor III
Target: ERK, MAPK, MNK
MK2-IN-1 hydrochloride
Cat.No: T4442
Synonym: MK2 Inhibitor,MK 25
Target: MAPK
MK-4827 Racemate
Cat.No: T22988
Synonym: Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
Target: PARP
MK-0159
Cat.No: T61933
Synonym:
Target: CD38
MK-28
Cat.No: T61859
Synonym:
Target: Antiviral, PERK
MK-6186
Cat.No: T68103
Synonym:
Target: Reverse Transcriptase
Ruzasvir
Cat.No: T68015
Synonym: MK8408,MK-8408,MK 8408
Target: HCV Protease
Laropiprant
Cat.No: T15712
Synonym: MK-0524
Target: Prostaglandin Receptor
Adavosertib
Cat.No: T2077
Synonym: AZD1775,MK-1775,Adavosertib (MK-1775)
Target: Wee1
Cat. No. Product Name Target Signaling Pathways
T0687 Simvastatin

辛伐他汀,MK-0733,MK 733

Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy Apoptosis; Autophagy; Metabolism
Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM),具有口服活性。Simvastatin 具有降血脂活性,可以抑制肝脏产生胆固醇,还可以用于预防心血管疾病。
T1131 Ivermectin

MK-933,伊维菌素

Mitophagy; GluCls; P2X Receptor; SARS-CoV; HIV Protease; Antibiotic; Parasite; Autophagy; HSV Autophagy; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Ivermectin (MK-933) 是谷氨酸门控氯离子通道激活剂,具有抗寄生虫活性。它特异性抑制Impα/β1 介导的核导入,还抑制牛疱疹病毒 1 复制并抑制BoHV-1DNA 聚合酶的核输入。它具有很强的抗病毒活性。它也是P2X4和 α7nAChRs 的正异构效应物。
T1207 Lovastatin

MK-803,洛伐他汀,Mevinolin

Ferroptosis; HMG-CoA Reductase; Autophagy Apoptosis; Autophagy; Metabolism
Lovastatin (MK-803) 是一种 HMG-CoA 还原酶抑制剂,用于降低胆固醇。
T1306 Norfloxacin

氟哌酸,MK-0366,诺氟沙星

DNA gyrase; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Norfloxacin (MK-0366) 是广谱抗生素,能通过结合DNA 旋转酶抑制革兰氏阳性和阴性菌。
T0505 Methyldopa

L-(-)-α-Methyldopa,MK-351,甲基多巴

Dopamine Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
L-(-)-α-Methyldopa (MK-351) 是一种前药,在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂,对 α2- adrenergic receptors 有选择性。
T75629 Ganoderic acid Mk

Ganoderic acid Mk (GA-Mk)为来源于灵芝菌丝的三萜酸类化合物,能有效抑制细胞增殖,并通过线粒体途径诱导HeLa细胞的细胞凋亡(apoptosis),在宫颈癌研究中具有应用价值。
TQ0203 Tafluprost

MK2452,AFP-168,他氟前列素

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Tafluprost 是一种抗青光眼前列腺素(PG)类似物。
T35782 Swinholide A

MK-7684

Antifungal Microbiology/Virology
Swinholide A 是可从海绵中提取的聚酮化合物,可于肌动蛋白结合,使肌动蛋白二聚化,Kd 约为 50 nM。Swinholide A 是一种细胞毒素,可稳定肌动蛋白二聚体并切断肌动蛋白丝。Swinholide A 具有抗真菌 (antifungal)活性,可破坏细胞的肌动蛋白细胞骨架。
T8262 Fosfomycin sodium

Fosfomycin Disodium,磷霉素钠

Antibacterial; Antibiotic Microbiology/Virology
Fosfomycin sodium 是一种能透过血脑屏障的广谱抗生素,不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性,包括耐多药、广泛耐药和耐全药的细菌。
T1505 Imipenem monohydrate

N-Formimidoyl thienamycin monohydrate,亚胺培南,Imipenem,亚胺培南一水物

Antibacterial; Antibiotic Microbiology/Virology
Imipenem monohydrate (Imipenem) 是从微生物 Streptomyces cattleya 分离得到的碳青霉烯类抗生素,是一种用于静脉注射的β 内酰胺类抗生素,作用于细菌细胞壁,能广泛有效抑制多种革兰氏阳性和阴性菌。
T7106 Menaquinone-4

四烯甲萘醌,Vitamin K2,Menaquinone K4

Others; Endogenous Metabolite Metabolism; Others
Menaquinone-4 (Vitamin K2) 是维生素 K 的一种,用作止血剂,有潜力用于骨质疏松的研究。
T21418 Lisinopril

Linopril,赖诺普利,Zestril,Prinivil,Lisipril

RAAS Endocrinology/Hormones
Lisinopril (Prinivil) 是一种血管紧张素转化酶抑制剂,能够作用于高血压,充血性心力衰竭和心脏病等。
TN2640 15-Methoxymkapwanin

Others Others
15-Methoxymkapwanin is a natural product from Dodonaea angustifolia.
T13555 Ascr#2

Ascaroside C6

Others Others
Ascr#2 (asc-C6-MK)是秀丽隐杆线虫中的糖苷类化合物,促进 dauer 形成。Ascr#2 在低浓度下与 ascr#3 的混合物可作为雄性引诱剂,可用于检测种群密度。
TN3605 Casegravol

Others Others
Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells.
T37008 Reveromycin A

Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in oste...

天然产物

Simvastatin
Cat.No: T0687
Synonym: 辛伐他汀,MK-0733,MK 733
Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy
Ivermectin
Cat.No: T1131
Synonym: MK-933,伊维菌素
Target: Mitophagy, GluCls, P2X Receptor, SARS-CoV, HIV Protease, Antibiotic, Parasite, Autophagy, HSV
Lovastatin
Cat.No: T1207
Synonym: MK-803,洛伐他汀,Mevinolin
Target: Ferroptosis, HMG-CoA Reductase, Autophagy
Norfloxacin
Cat.No: T1306
Synonym: 氟哌酸,MK-0366,诺氟沙星
Target: DNA gyrase, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic
Methyldopa
Cat.No: T0505
Synonym: L-(-)-α-Methyldopa,MK-351,甲基多巴
Target: Dopamine Receptor, Adrenergic Receptor
Ganoderic acid Mk
Cat.No: T75629
Synonym:
Target:
Tafluprost
Cat.No: TQ0203
Synonym: MK2452,AFP-168,他氟前列素
Target: Prostaglandin Receptor
Swinholide A
Cat.No: T35782
Synonym: MK-7684
Target: Antifungal
Fosfomycin sodium
Cat.No: T8262
Synonym: Fosfomycin Disodium,磷霉素钠
Target: Antibacterial, Antibiotic
Imipenem monohydrate
Cat.No: T1505
Synonym: N-Formimidoyl thienamycin monohydrate,亚胺培南,Imipenem,亚胺培南一水物
Target: Antibacterial, Antibiotic
Menaquinone-4
Cat.No: T7106
Synonym: 四烯甲萘醌,Vitamin K2,Menaquinone K4
Target: Others, Endogenous Metabolite
Lisinopril
Cat.No: T21418
Synonym: Linopril,赖诺普利,Zestril,Prinivil,Lisipril
Target: RAAS
15-Methoxymkapwanin
Cat.No: TN2640
Synonym:
Target: Others
Ascr#2
Cat.No: T13555
Synonym: Ascaroside C6
Target: Others
Casegravol
Cat.No: TN3605
Synonym:
Target: Others
Reveromycin A
Cat.No: T37008
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01300 EpCAM/TROP1 Protein, Human, Recombinant (His)

TROP-1,ESA,EGP40,HNPCC8,EGP314,M4S1,epithelial cell adhesion...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.84 kDa and the accession number is P16422.
TMPY-05587 EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated

HNPCC8,EGP314,KSA,KS1/4,TROP1,ESA,DIAR5,TROP-1,MIC18,EGP40,<...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 30.7 kDa and the accession number is P16422.
TMPK-00812 Midkine Protein, Mouse, Recombinant (His)

MK1,ARAP,MKARAP,MEK,MK,NEGF2,MDK

Mouse E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mo...
TMPK-00023 Midkine Protein, Human, Recombinant (His & Avi)

MDK,MEK,MK1,MKARAP,ARAP,MK,NEGF2

Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPK-00024 Midkine Protein, Human, Recombinant (His & Avi), Biotinylated

MK1,MK,MDK,NEGF2,MKARAP,MEK,ARAP

Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPK-00696 PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)

MAPKAPK5,MK5,MAPKAP-K5,MK-5,MAPKAPK-5

Human Baculovirus Insect Cells
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway.
TMPY-04476 MVK Protein, Human, Recombinant (His & GST)

POROK3,LRBP,MVLK,MK,mevalonate kinase

Human Baculovirus Insect Cells
Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be a regulatory site in the cholesterol biosynthetic pathway. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia,...
TMPY-02172 Midkine Protein, Human, Recombinant

midkine (neurite growth-promoting factor 2),NEGF2,MK

Human Baculovirus Insect Cells
Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angio...
TMPY-04425 PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)

PRAK,MAPKAP-K5,MK-5,mitogen-activated protein kinas...

Human Baculovirus Insect Cells
MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK). It is widely distributed. MAPKAPK5 can be phosphorylated by an extracellular-regulated kinase (ERK), and p38 kinase but not by c-jun N-terminal kinase (JNK)in vitro. Recombinant GST-MAPKAPK5 protein can phosphorylate a peptide derived from the regulator...
TMPJ-00246 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)

MK,CD262,Tnfrsf10b,Dr5,Tumor necrosis factor recept...

Mouse HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-75 KDa and the accession number is Q9QZM4.
TMPY-04378 MAPKAPK3 Protein, Human, Recombinant (GST)

mitogen-activated protein kinase-activated protein kinase 3,...

Human Baculovirus Insect Cells
The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identified and serve as substrates for the ERK and p38 MAP kinases. Mitogen-activated protein (MAP) kinase-activated protein kinase 3, also known as MAPKAPK-3 and 3pK, is a member of the Ser/Thr protein kinase family. It is widely expressed in hu...
TMPY-01437 DR5/TRAIL R2 Protein, Mouse, Recombinant (His)

TRAILR2,MK,TRICKB,TRICK2B,TRICK2A,Ly98,DR5,KILLER,t...

Mouse HEK293 Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is Q9QZM4.
TMPY-01452 DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)

TRICK2B,DR5,tumor necrosis factor receptor superfamily, memb...

Mouse HEK293 Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q9QZM4.
TMPJ-00245 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated

Dr5,CD262,Death receptor 5,Tnfrsf10b,Killer,MK,Tumo...

Mouse HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 20-40 KDa and the accession number is Q9QZM4.
TMPK-00874 Thyroid Peroxidase Protein, Mouse, Recombinant (His)

MK-CSF,MGDF,ML,MPLLG,THPO,TPOMKCSF,Thrombo...

Mouse HEK293 Cells
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune t...
TMPY-00785 EpCAM/TROP1 Protein, Human, Recombinant (hFc)

KSA,DIAR5,HNPCC8,TACSTD1,KS1/4,ESA,MK-1,MIC18,epith...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54 kDa and the accession number is P16422.
TMPY-06849 EpCAM/TROP1 Protein, Human, Recombinant (mFc)

DIAR5,M4S1,EGP314,ESA,epithelial cell adhesion molecule,TROP...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 53.81 kDa and the accession number is NP_002345.1.
TMPY-05601 EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

MK-1,TROP1,EGP314,DIAR5,HNPCC8,TROP-1,KSA,MIC18,KS1...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 56 kDa and the accession number is P16422.
TMPY-05117 EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated

EGP314,DIAR5,TACSTD1,MK-1,KSA,MIC18,ESA,EGP40,epith...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is P16422.
TMPY-04953 EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated

M4S1,EGP-2,DIAR5,TROP1,TROP-1,HNPCC8,epithelial cell adhesio...

Human HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P16422.
TMPK-00679 EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant

EpCAM,ACSTD1,ESA,MK1,EGP-2,EGP,MOC31,HNPCC8,EGP40,T...

Cynomolgus,Rhesus HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.38 kDa and the accession number is Q1WER1.
TMPK-00680 EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

EGP40,EGP314,CD326,EGP,KSA,HNPCC8,ESA,DIAR5,MOC31,TROP1,TACS...

Cynomolgus,Rhesus HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.5 kDa and the accession number is Q1WER1.
TMPK-00205 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated

EGP40,TROP1,EGP314,MIC18,DIAR5,ESA,KSA,TACST-1,EpCAM,EGP,MOC...

Human HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P1...
TMPK-00206 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)

ESA,TACSTD1,EGP-2,TROP1,EpCAM,EGP314,MOC31,DIAR5,CD326,gp40,...

Human HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 54.2 kDa and the accession number is P16422.
TMPK-00207 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)

DIAR5,MOC31,EGP,MK1,HNPCC8,EGP314,ESA,MIC18,TROP1,E...

Human HEK293 Cells
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.2 kDa and the accession number is P16422.
TMPY-04572 MKK4 Protein, Mouse, Recombinant (His & GST)

MKK4,MEK4,PRKMK4,Sek1,JNKK1,Serk1,mitogen-...

Mouse Baculovirus Insect Cells
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is a protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase that is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / ...
TMPY-04364 MKK6 Protein, Human, Recombinant (His & GST)

MKK6,mitogen-activated protein kinase kinase 6,SAPK...

Human Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.
TMPH-01026 CAMK2N1 Protein, Human, Recombinant (His & Trx)

Calcium/calmodulin-dependent protein kinase II inhibitor 1,C...

Human E. coli
Potent and specific inhibitor of CaM-kinase II (CAMK2). CAMK2N1 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with N-6xHis-Trx tag. The predicted molecular weight is 25.6 kDa and the accession number is Q7Z7J9.
TMPY-04423 CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)

VWS1,RP1-272L16.2,calcium/calmodulin-dependent protein kinas...

Human Baculovirus Insect Cells
Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein phosphorylate multiple downstream targets. Concentration of cytosolic calcium functions as a second messenger that mediates a wide range of cellular responses. Calcium binds to calcium binding proteins (calmodulin/CaM) and stimulates the activity of a variety of enzymes, including CaM kinases referred to as CaM-kinases (CaMKs), such as CaMKI, CaMKII, CaMKIV and CaMKK. Calmodulin-dependent protein kinase CL3/CaMKIγ is a membera...
TMPH-02689 Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)

Mouse E. coli
Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 33.9 kDa. Accession number: O35205
TMPH-01917 MKI67 Protein, Human, Recombinant (E. coli, His)

Human E. coli
MKI67 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPY-04415 CAMKI Protein, Human, Recombinant

calcium/calmodulin-dependent protein kinase I,CAMKI

Human E. coli
CAMKI Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 41.5 kDa and the accession number is B0YIY3.
TMPY-04566 CAMKV Protein, Human, Recombinant (His & GST)

1G5,VACAMKL,CaM kinase-like vesicle-associated

Human Baculovirus Insect Cells
CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase family. CAMKV contains oneprotein kinase domain. It is predominantly observed in association with the plasma membrane of soma and in neurites, both axons and dendrites. CAMKV may be associated with vesicular structures. It does not appear to have detectable kinase activity. ...
TMPY-04408 CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)

calcium/calmodulin-dependent protein kinase II beta,CAM2,CA<...

Human Baculovirus Insect Cells
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in prostate cancer cells ability to escape apoptosis under androgen ablation and facilitate the progression of prostate cancer cells to an androgen independent state. As a multifunctional protein kinase, the loss of activity may play a critical role in initiating the changes leading to...
TMPY-04543 CAMKIV Protein, Human, Recombinant (GST)

caMK,CaMK-GR,IV,CaMKIV,calcium/ca...

Human Baculovirus Insect Cells
CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 79 kDa and the accession number is Q16566.
TMPY-02420 HEMK2 Protein, Human, Recombinant (His)

N-6 adenine-specific DNA methyltransferase 1 (putative),HE

Human E. coli
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to the eukaryotic/archaeal PrmC-related family. The encoded enzyme may be involved in the methylation of release factor I during translation termination. N6AMT1 has a significant role in determining susceptibility to arsenic toxicity and carcinogenicity because of its specific activi...
TMPY-03105 Ki67/MKI67 Protein, Human, Recombinant (GST)

MIB-1,PPP1R105,marker of proliferation Ki-67,MIB-,KIA

Human E. coli
MKI67 contains 1 FHA domain and plays a key role in cell proliferation. During interphase, the MKI67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. MKI67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells. MKI67 is an excellent marker to determine the growth fraction of a given cell population. The fraction of MKI67-positive tu...
TMPH-03265 CMKLR2 Protein, Rat, Recombinant (His)

Chemerin chemokine-like receptor 2,Gpr1,Chemokine-like recep...

Rat E. coli
Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway.
TMPJ-00240 CAMK1 Protein, Human, Recombinant (His)

CaM Kinase I Alpha,CaMKI-α,CaM Kinase I,CAMK

Human HEK293 Cells
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed. CAMK1 is phosphorylated by CaMKK1 and CaMKK2 on Thr-177. CAMK1 regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization, and neurite outgrowth. CAMK1 plays a role in K+ and ANG2-mediated regulation of the aldo...
TMPH-01082 CMKLR1 Protein, Human, Recombinant (His)

CMKLR1,G-protein coupled receptor ChemR23,G-protein...

Human E. coli
CMKLR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is Q99788.
TMPY-06567 Granzyme K/GZMK Protein, Human, Recombinant (His)

granzyme K,TRYP2

Human HEK293 Cells
Granzyme K/GZMK Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.56 kDa and the accession number is NP_002095.1.
TMPY-04759 CAMKIV Protein, Mouse, Recombinant

D18Bwg0362e,CaMKIV,AI666733,A430110E23Rik,calcium/c...

Mouse Baculovirus Insect Cells
CAMKIV Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 52.7 kDa and the accession number is P08414.
TMPY-04749 MKK6 Protein, Human, Recombinant (S207D, T211D)

MAPKK6,PRKMK6,MKK6,MEK6,mitogen-activated ...

Human Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant (S207D, T211D) is expressed in Baculovirus insect cells. The predicted molecular weight is 37.7 kDa and the accession number is P52564-1.
TMPY-04365 MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)

SAPKK3,mitogen-activated protein kinase kinase 6,MK...

Human Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.
TMPY-04573 CAMKIV Protein, Mouse, Recombinant (His & GST)

CaMKIV,D18Bwg0362e,calcium/calmodulin-dependent pro...

Mouse Baculovirus Insect Cells
CAMKIV Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 80.4 kDa and the accession number is P08414.
TMPY-04748 MKK6 Protein, Human, Recombinant

MKK6,MAPKK6,SAPKK-3,SAPKK3,PRKMK6,MEK6,mit...

Human Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 37.6 kDa and the accession number is A8K3Y2.
TMPJ-00905 DTYMK Protein, Human, Recombinant (His)

DTYMK,TMPK,dTMP kinase,Thymidylate kinase,CDC8,TY

Human HEK293 Cells
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest ...
TMPJ-01436 MKI67 Protein, Human, Recombinant (GST)

Ki-67,Antigen Ki67,MKI67,KIA,antigen KI-67,MIB-1,MI...

Human E. coli
MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition...
TMPH-01918 MKI67 Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
MKI67 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPY-04373 CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST)

calcium/calmodulin-dependent protein kinase II alpha,calcium...

Human Baculovirus Insect Cells
Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily. CaM kinase Ⅱ is thought to be an important mediator of learning and memory and is also necessary for Ca2+homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CAMKIIA is one of the major forms of CAMKII...
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重组蛋白

EpCAM/TROP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01300
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05587
Species: Human
Expression System: HEK293 Cells
Midkine Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00812
Species: Mouse
Expression System: E. coli
Midkine Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00023
Species: Human
Expression System: E. coli
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00024
Species: Human
Expression System: E. coli
PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)
Cat.No: TMPK-00696
Species: Human
Expression System: Baculovirus Insect Cells
MVK Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04476
Species: Human
Expression System: Baculovirus Insect Cells
Midkine Protein, Human, Recombinant
Cat.No: TMPY-02172
Species: Human
Expression System: Baculovirus Insect Cells
PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04425
Species: Human
Expression System: Baculovirus Insect Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00246
Species: Mouse
Expression System: HEK293 Cells
MAPKAPK3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04378
Species: Human
Expression System: Baculovirus Insect Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01437
Species: Mouse
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-01452
Species: Mouse
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00245
Species: Mouse
Expression System: HEK293 Cells
Thyroid Peroxidase Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00874
Species: Mouse
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00785
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-06849
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05601
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05117
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04953
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant
Cat.No: TMPK-00679
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00680
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated
Cat.No: TMPK-00205
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)
Cat.No: TMPK-00206
Species: Human
Expression System: HEK293 Cells
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)
Cat.No: TMPK-00207
Species: Human
Expression System: HEK293 Cells
MKK4 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-04572
Species: Mouse
Expression System: Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04364
Species: Human
Expression System: Baculovirus Insect Cells
CAMK2N1 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPH-01026
Species: Human
Expression System: E. coli
CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04423
Species: Human
Expression System: Baculovirus Insect Cells
Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02689
Species: Mouse
Expression System: E. coli
MKI67 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01917
Species: Human
Expression System: E. coli
CAMKI Protein, Human, Recombinant
Cat.No: TMPY-04415
Species: Human
Expression System: E. coli
CAMKV Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04566
Species: Human
Expression System: Baculovirus Insect Cells
CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04408
Species: Human
Expression System: Baculovirus Insect Cells
CAMKIV Protein, Human, Recombinant (GST)
Cat.No: TMPY-04543
Species: Human
Expression System: Baculovirus Insect Cells
HEMK2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02420
Species: Human
Expression System: E. coli
Ki67/MKI67 Protein, Human, Recombinant (GST)
Cat.No: TMPY-03105
Species: Human
Expression System: E. coli
CMKLR2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03265
Species: Rat
Expression System: E. coli
CAMK1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00240
Species: Human
Expression System: HEK293 Cells
CMKLR1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01082
Species: Human
Expression System: E. coli
Granzyme K/GZMK Protein, Human, Recombinant (His)
Cat.No: TMPY-06567
Species: Human
Expression System: HEK293 Cells
CAMKIV Protein, Mouse, Recombinant
Cat.No: TMPY-04759
Species: Mouse
Expression System: Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant (S207D, T211D)
Cat.No: TMPY-04749
Species: Human
Expression System: Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)
Cat.No: TMPY-04365
Species: Human
Expression System: Baculovirus Insect Cells
CAMKIV Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-04573
Species: Mouse
Expression System: Baculovirus Insect Cells
MKK6 Protein, Human, Recombinant
Cat.No: TMPY-04748
Species: Human
Expression System: Baculovirus Insect Cells
DTYMK Protein, Human, Recombinant (His)
Cat.No: TMPJ-00905
Species: Human
Expression System: HEK293 Cells
MKI67 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01436
Species: Human
Expression System: E. coli
MKI67 Protein, Human, Recombinant (His)
Cat.No: TMPH-01918
Species: Human
Expression System: P. pastoris (Yeast)
CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST)
Cat.No: TMPY-04373
Species: Human
Expression System: Baculovirus Insect Cells
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