886
228
14
10
319
Cat. No. | Product Name | ||
---|---|---|---|
L6750 | 活血化瘀中药单体库 | 580 compounds | |
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。 | |||
L6001 | Mini真菌代谢天然产物筛选库 | Inquiry | |
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L2192 | 抗胰腺癌化合物库 | 2238 compounds | |
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L9300 | 大环化合物库 | 210 compounds | |
210 种活性已知的大环化合物,用于高通量、高内涵筛选; | |||
L2540 | 肠道微生物代谢化合物库 | 607 compounds | |
607 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选; | |||
L1380 | 转录因子库 | 695 compounds | |
695 种转录因子靶向、结构新颖的化合物; | |||
L9500 | 表型筛选靶点鉴定库 | 1796 compounds | |
1796 种靶点明确的已知活性化合物,适合表型筛选; | |||
L1580 | GPCR库Plus | 338 compounds | |
338 种GPCR 靶向、结构新颖的化合物; | |||
L2400 | 内分泌激素分子库 | 784 compounds | |
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6500 | 微生物天然产物库 | 550 compounds | |
550 种微生物来源的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L7820 | 高溶解性微型片段化合物库 | 1081 compounds | |
高溶解性微型片段化合物库由 1081 个低分子量片段组成。 | |||
L1500 | GPCR靶点分子库 | 1940 compounds | |
1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物,所有小分子都具有良好的生物和药理活性,部分是 FDA 批准的上市药物; | |||
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0007 |
SYBR Green qPCR Master Mix (High ROX)
SYBR Green qPCR Master Mix (High ROX) |
Solution in bottle | |
C0006 |
SYBR Green qPCR Master Mix (No ROX)
SYBR Green qPCR Master Mix (No ROX) |
Solution in bottle | |
C0008 |
SYBR Green qPCR Master Mix (Low ROX)
SYBR Green qPCR Master Mix (Low ROX) |
Solution in bottle | |
CL0120 |
Bcr-Abl inhibitor/degrader kit
Bcr-Abl inhibitor/degrader kit |
||
CL0149 |
β-/γ-secretase inhibitor kit
β-/γ-secretase inhibitor kit |
||
CL0133 |
CXCR inhibitor kit
CXCR inhibitor kit |
||
CL0108 |
DNA Alkylator/Crosslinker kit
DNA Alkylator/Crosslinker kit |
||
CL0074 |
Microtubule/Tubulin inhibitor kit
Microtubule/Tubulin inhibitor kit |
||
CL0128 |
HMGCR inhibitor kit
HMGCR inhibitor kit |
||
CL0077 |
Reverse Transcriptase inhibitor kit
Reverse Transcriptase inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27640 |
Itriglumide
CR-2945,CR2945,CR 2945 |
||
Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD). | |||
T68016 |
Spiroglumide
CR-2194 |
cholecystokinin | GPCR/G Protein |
Spiroglumide 是一种CCKB-胃泌素拮抗剂,能够抑制剂量依赖性五肽胃泌素诱导的酸分泌过多,其ID50为20.1(8.67-46.4)mg / kg,可用于探索胃泌素在调节人类胃酸分泌中的生理作用。 | |||
T11868 |
Lorglumide sodium salt
CR-1409 sodium salt |
cholecystokinin | GPCR/G Protein |
Lorglumide sodium salt (CR-1409 sodium salt) 是胆囊收缩素受体 (CCK) 的拮抗剂。 | |||
T31089 |
CR 39
PADC,CR39,PM 600,CR-39,Lantrak 2 |
||
CR 39, a plastic, can be used as a charged particle detector for superimposed autoradiography tissue images. | |||
T12617 |
(R)-CR8 trihydrochloride
CR8, (R)-Isomer trihydrochloride |
Apoptosis; CDK | Apoptosis; Cell Cycle/Checkpoint |
(R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) 是一种 CDK1/2/5/7/9 抑制剂,可作为分子胶降解剂,具有神经保护活性,可诱导细胞凋亡。 | |||
T2312 |
Loxiglumide
CR-1505,氯谷胺 |
cholecystokinin | GPCR/G Protein |
Loxiglumide (CR-1505) 是一种缩胆囊素受体拮抗剂。 | |||
T15010 |
CR4056
6-(1H-imidazol-1-yl)-2-phenylquinazoline |
MAO; Imidazoline Receptor | Metabolism; Neuroscience |
CR4056 (6-(1H-imidazol-1-yl)-2-phenylquinazoline) 是一种特异性 MAO-A 抑制剂,IC50 为 202.7 nM,是 I2-咪唑啉受体的配体,IC50 为 596 nM。 | |||
T27079 |
CR-665 Acetate
FE200665,CR-665,JNJ-38488502,CR665,FE-200665,JNJ38488502 |
||
CR-665, a kappa-opioid agonist, is used potentially for the treatment of postoperative pain. | |||
T70718 |
CR-6086
|
||
CR6086 is a novel, potent EP4 antagonist showing favourable immunomodulatory properties, striking DMARD effects in rodents, and anti-inflammatory activity targeted to immune-mediated inflammatory diseases and distinct from the general effects of cyclooxygenase inhibitors. CR6086 showed selectivity and high affinity for the human EP4 receptor (Ki = 16.6 nM) and functioned as a pure antagonist (half-maximal inhibitory concentration, 22 nM) on PGE2-stimulated cAMP production. | |||
T12617L |
(R)-CR8
(R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8 |
Apoptosis; CDK | Apoptosis; Cell Cycle/Checkpoint |
(R)-CR8 ((R)-Isomer) 是 Roscovitine 类似物,是CDK1/2/5/7/9抑制剂。它作为一种分子胶降解剂来消耗细胞周期蛋白 K。它诱导细胞凋亡并具有神经保护作用。 | |||
T74178 |
Glembatumumab vedotin
CR011-vcMMAE,CR 011 ADC,CDX-011 |
Microtubule Associated | Cytoskeletal Signaling |
Glembatumumab vedotin (CDX-011) 是一种抗体活性小分子偶联物,Glembatumumab vedotin 具有强大的抗癌作用,可用于研究三阴性乳腺癌(TNBC)。 | |||
T38753 |
CR-1-31-B
|
||
CR-1-31-B, a synthetic rocaglate, acts as a highly potent inhibitor of eIF4A. By disrupting the interaction between eIF4A and RNA, it effectively obstructs the initiation phase of protein synthesis. Specifically, CR-1-31-B interferes with the association between Plasmodium falciparum eIF4A (PfeIF4A) and RNA. Additionally, CR-1-31-B induces apoptosis in neuroblastoma and gallbladder cancer cells [4]. | |||
T73522 |
CR 665
FE 200665,JNJ 38488502 ; FE 200665,JNJ 38488502 |
||
CR 665 (JNJ 38488502) 是一种外周选择性κ-阿片类激动剂。CR 665可以激活 kappa 阿片受体 EC50值为10.9 nM。CR 665 可用于外周疼痛的研究。 | |||
TP2501 |
Difelikefalin acetate
Difelikefalin acetate(1024828-77-0 free base),CR 845 acetate,Difelikefalin醋酸盐,FE 202845 acetate |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Difelikefalin acetate (CR 845 acetate) 是一种外周受限的 kappa 阿片受体激动剂。CR845 表现出低 P450 CYP 抑制和对大脑的低渗透性。 | |||
T24887 |
Tiropramide
CR-605 |
||
Tiropramide is an antispasmodic drug. It also useful to inhibit the contractile response of the urinary bladder and in managing abdominal pain in IBS. | |||
T26628 |
Andolast
CR2039,CR-2039,CR 2039 |
||
Andolast, also known as CR-2039, an anti-allergic agent for the treatment of bronchial asthma, chronic obstructive pulmonary disease (COPD). Andolast acts at different cellular levels to inhibit immunoglobulin E synthesis. Andolast proved to be significan | |||
T28152 |
Neboglamine
XY 2401,CR-2249,XY-2401,CR2249,XY2401,CR 2249 |
||
Neboglamine, a glycine NMDA-associated agonist, is used potentially for the treatment of schizophrenia. | |||
T38419 |
Difelikefalin
CR-845,FE-202845 |
||
Difelikefalin (CR-845; FE-202845) is a peripherally restricted, selective agonist of the kappa opioid receptor (KOR). It exhibits anti-inflammatory properties and holds promise for modulating pruritus in conditions associated with chronic kidney disease. | |||
T36654 |
Anti-SARS-CoV-2 Spike mAb (CR3022)
Anti-SARS-CoV-2 Spike mAb (CR3022) |
||
Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2. | |||
T4575 |
Chromium picolinate
|
DNA; p38 MAPK | DNA Damage/DNA Repair; MAPK |
Chromium picolinate 具有降低胰岛素抵抗的作用,对 2 型糖尿病具有潜在的研究价值。 | |||
T23577 |
(S)-CR8
(S)CR8,(S) CR8 |
||
(S)-CR8 is an effective second-generation cyclin-dependent kinase inhibitor. | |||
T78315 |
Foravirumab
CR4098 |
||
Foravirumab (CR4098)为针对狂犬病病毒糖蛋白的抗原位点III的单克隆抗体,适用于狂犬病相关研究。 | |||
T69537 |
Difelikefalin HCl
|
||
Difelikefalin HCl is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin HCl is selective for KOR over the μ-opioid receptor (MOR; EC50 = >1 µM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07... | |||
T69530 |
Difelikefalin TFA
|
||
Difelikefalin TFA is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin TFA is selective for KOR over the μ-opioid receptor (MOR; EC50 = >1 µM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07... | |||
T70716 |
ArgTX-48 TFA
|
||
ArgTX-48 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs. | |||
T69348 |
LS-104
|
||
LS-104 is a JAK2 inhibitor. | |||
TD0062 |
6-CR110 [6-Carboxyrhodamine 110] *Single isomer*
6-羧基罗丹明110(单一化合物) |
||
6-CR110 [6-Carboxyrhodamine 110] *Single isomer* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. | |||
TD0061 |
5-CR110 [5-Carboxyrhodamine 110] *Single isomer*
5-羧基罗丹明110(单一化合物) |
||
5-CR110 [5-Carboxyrhodamine 110] *Single isomer* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. | |||
TD0064 |
5-CR110, SE [5-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*
5-羧基罗丹明110琥珀酰亚胺酯(单一化合物) |
||
Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 489 nm excitation wavelength. They are photostable alternative reag | |||
TD0060 |
5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers*
5(6)-羧基罗丹明110(混合物) |
||
5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. | |||
TD0065 |
6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*
6-羧基罗丹明110琥珀酰亚胺酯(单一化合物) |
||
6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. | |||
TD0063 |
5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers*
5(6)-羧基罗丹明110琥珀酰亚胺酯(混合物) |
||
5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. | |||
T67508 |
(2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-Dihydroxy-4a,6a-dimethylhexadecahydro-1H-cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthren-7(7aH)-one
|
||
(2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-Dihydroxy-4a,6a-dimethylhexadecahydro-1H-cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthren-7(7aH)-one 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67508,CAS号为 82543-16-6。 | |||
T8636 |
Ibrutinib deacryloylpiperidine
IBT4A,5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine,伊布替尼中间体N-2 |
BTK | Angiogenesis; Tyrosine Kinase/Adaptors |
Ibrutinib deacryloylpiperidine (IBT4A) 是 Ibrutinib 的杂质之一。它是一种不可逆的、选择性的 Btk 抑制剂 (IC50:0.5 nM)。 | |||
T1724 |
SCR7 pyrazine
SCR7,SCR7 吡嗪 |
Apoptosis; DNA/RNA Synthesis; CRISPR/Cas9 | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
SCR7 pyrazine (SCR7) 是一种 DNA 连接酶 IV 抑制剂,以连接酶 IV 依赖的方式阻断非同源末端连接。它也是 CRISPR/Cas9的增强子,可提高 Cas9 介导的同源性定向修复的效率。它诱导细胞凋亡,具有抗癌活性。 | |||
T72958 |
BCR-ABL-IN-7
|
Bcr-Abl | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
BCR-ABL-IN-7 是一种 WT 和 T315I 突变体 ABL 激酶抑制剂。BCR-ABL-IN-7 有效抑制 WT 和 T315I 突变体 ABL 激酶的活性。BCR-ABL-IN-7 可以用于慢性髓系白血病 (CML) 的研究。 | |||
T5446 |
CIBACRON BLUE 3G-A
|
Others | Others |
Cibacron Blue 3G-A 是蒽醌染料,能够抑制 R46β-lactamase(Ki:1.2 uM)。 | |||
T28226 |
Octahydroaminoacridine succinate
|
Others | Others |
Octahydroaminoacridine succinate 是一种乙酰胆碱酯酶抑制剂,可用于治疗阿尔茨海默病。 | |||
T13114 |
CCR2 antagonist 4
Teijin compound 1 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2 antagonist 4 (Teijin compound 1) 是高效的、特异性的CCR2拮抗剂,对 CCR2b 的IC50为 180 nM,抑制 MCP-1 诱导的趋化作用的 IC50为 24 nM。 | |||
T37558 |
Necrostatin-5
Nec-5 |
RIP kinase; Necroptosis | Apoptosis; NF-κB |
Necrostatin-5 (Nec-5)是一种RIP1激酶的选择性抑制剂,也是一种细胞坏死抑制剂,可防止TNF-α处理的fadd 缺陷Jurkat 细胞死亡,EC50值为240 nM。 | |||
T4367 |
Mycro 3
Mycro-3 |
c-Myc; Autophagy | Autophagy; Cell Cycle/Checkpoint |
Mycro 3 在全细胞分析中对 c-Myc 具有强效选择性,可用于胰腺癌的研究。 | |||
T3521 |
γ-Secretase-IN-1
Compound E |
Beta Amyloid; Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
γ-Secretase-IN-1 是一种高效的 γ-secretase 抑制剂,对T-47D 细胞显示部分抗增殖活性且抑制 β-amyloid(40),β-amyloid(42),和Notch γ-分泌酶裂解。 | |||
T4302 |
iCRT3
|
Apoptosis; Wnt/beta-catenin | Apoptosis; Cytoskeletal Signaling; Stem Cells |
iCRT3 是一种Wnt 和 β-连环蛋白应答转录抑制剂。 | |||
TQ0297 |
Cenicriviroc
TAK-652,TBR-652 |
HIV Protease; CCR | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
Cenicriviroc (TAK-652) 是一种可口服的CCR2/CCR5拮抗剂,可抑制 HIV-1 和 HIV-2,具有抗炎、抗感染作用。 | |||
T28475 |
Pyrazoloacridine
PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934 |
Apoptosis; Topoisomerase | Apoptosis; DNA Damage/DNA Repair |
Pyrazoloacridine (PD 115934) 是一种核酸结合剂,在 K562 细胞中抑制 topo I 和 II 的活性,IC50 为 1.25 μM。 Pyrazoloacridine 具有抗癌活性。 | |||
T0517 |
Pancreatin
Pancreatic enzymes,pancrelipase,胰酶 |
Others | Others |
Pancreatin (pancrelipase) 是一种含有胰腺消化酶的猪胰腺提取物。 | |||
T63727 |
CRK12-IN-2
|
Parasite | Microbiology/Virology |
CRK12-IN-2 是一种有效的 CRK12 的抑制剂。CRK12-IN-2 对寄生虫具有抑制作,对Trypanosoma congolense 和 Trypanosoma vivax 的 EC50 值分别为 3.2 和 0.08 nM。CRK12-IN-2 可用于预防和治疗动物锥体虫病。 | |||
T27682 |
CCR2 antagonist 5
JNJ-41443532,JNJ-41443532 Free Base,JNJ 41443532,JNJ41443532 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2 antagonist 5 (JNJ-41443532) 是一种具有选择性和口服活性的 hCCR2 抑制剂,具有良好的结合亲和力 (IC50=37 nM) 和有效的功能拮抗作用 (chemotaxis IC50=30 nM)。JNJ-41443532 对 mCCR2 结合的 Ki 为 9.6 µM, 可用于研究炎症性疾病和糖尿病。 | |||
T62263 |
γ-Secretase modulator 13
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
γ-Secretase modulator 13 是一种 γ-分泌酶调节剂 (GSMs),可以抑制淀粉样蛋白 β 肽Aβ42 的产生,可以用于研究阿尔茨海默病和肿瘤。 | |||
TP1676L |
C-Reactive Protein (CRP) 201-206 acetate
C-Reactive Protein (CRP) 201-206 acetate(130348-99-1 free base) |
Others | Others |
C-Reactive Protein (CRP) 201-206 acetate (C-Reactive Protein )(130348-99-1 free base) 是 C-反应蛋白的 201-206 片段。 C-反应蛋白 (CRP) 醋酸盐是炎症的原型标志物,是心血管风险标志物,可能促进动脉粥样硬化形成。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6780 |
Carvacrol methyl ether
Methyl carvacrol,Methyl carvacryl ether |
Antibacterial | Microbiology/Virology |
Carvacrol methyl ether 来源于植物挥发油,具有抗菌活性。 | |||
T3858 |
macranthoidin A
灰毡毛忍冬皂苷甲,金银花 |
Others | Others |
Macranthoidin A 是一种具有口服活性的、提取于金银花中的皂苷。它对四氯化碳,对乙酰氨基酚和镉所致的肝损伤具有保护作用,对耳巴豆油的溶胀具有明显的抑制作用。 | |||
T16535 |
Picrotoxinin
|
Chloride channel; GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Picrotoxinin 是一种氯离子通道阻断剂和 GABAA 的非竞争性拮抗剂,对 α1β2γ2L GABAA 的 IC50 为 1.15 μM。 Picrotoxinin 具有惊厥作用。 | |||
T3779 |
Crocin II
Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B |
Caspase; COX; NO Synthase | Apoptosis; Immunology/Inflammation; Neuroscience; Proteases/Proteasome |
Crocin II (Crocetin gentiobiosylglucosyl ester) 是从栀子果实中分离出来的一种天然产物,具有抗氧化、抗癌和抗抑郁活性。它抑制 iNOS 和 COX-2的蛋白质和 m-RNA 的表达,还抑制NO 产生,IC50值为 31.1 μM。 | |||
TN1932 |
Microhelenin C
|
Others | Others |
Microhelenin C 是抑制从Helenium microcephalum 中提取的倍半萜内酯,具有抗肿瘤作用。 | |||
T3S0027 |
Picropodophyllotoxin
AXL 1717,Picropodophyllin,苦鬼臼毒素 |
IGF-1R | Tyrosine Kinase/Adaptors |
Picropodophyllotoxin (AXL 1717) 是一种环木脂素生物碱,存在于五月树(Podophyllum peltatum) 中,是一种具有潜在抗肿瘤活性的胰岛素样生长因子 1 受体 (IGF1R) 的小分子抑制剂。它特异性抑制 IGF1R 的活性并下调细胞表达,而不干扰其他生长因子受体的活性,例如胰岛素受体、表皮生长因子、血小板衍生生长因子、成纤维细胞生长因子和肥大/干细胞生长因子 (KIT) )。该药剂在抑制肿瘤细胞增殖和诱导肿瘤细胞凋亡方面显示出有效的活性。 IGF1R 是一种在多种人类癌症中过度表达的受体酪氨酸激酶,在多种癌细胞的生长和存活中起关键作用。 | |||
TN6967 |
(R)-Isomucronulatol
(-)-Isomucronulatol,2H-1-Benzopyran-7-ol |
Apoptosis | Apoptosis |
(R)-Isomucronulatol (2H-1-Benzopyran-7-ol) 是一种可从黄芪、刺槐、虎杖和甘草叶片中提取得到的类黄酮,抑制BMSCs 在TNF-α微环境中的增殖和凋亡。(R)-Isomucronulatol 具有潜在的抗炎活性。 | |||
T67710 |
3-Indoleacrylic acid
|
Endogenous Metabolite | Metabolism |
3-Indoleacrylic acid 是由链球菌属产生的色氨酸的代谢产物。3-Indoleacrylic acid 对肠上皮屏障功能有有益作用,并减轻免疫细胞的炎症反应。 | |||
T41095 |
(E)-3-(4-Methoxyphenyl)acrylic acid
(E)-3-(4-甲氧基苯基)丙烯酸 |
Glucosidase | Metabolism |
(E)-3-(4-Methoxyphenyl)acrylic acid 是从 Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. 的根茎中分离出来的一种小分子化合物。它是一种新型 α-葡萄糖苷酶抑制剂。(E)-3-(4-甲氧基苯基)丙烯酸具有保肝活性、抗失水活性、增强认知效果,并可用于降低血压血糖。 | |||
T22300 |
Creatine monohydrate
Methylguanidoacetic acid monohydrate,一水肌酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Creatine monohydrate (Methylguanidoacetic acid monohydrate) 是磷酸原能量系统的关键参与者,尤其是在肌肉和大脑中。 Creatine monohydrate 是高强度、短期活动中 ATP 的主要来源。 | |||
T2817 |
Picroside II
胡黄连苷II,Vanilloyl catalpol,6-Vanilloylcatalpol,胡黄连苦苷II |
Apoptosis; Others; Influenza Virus; NF-κB; Reactive Oxygen Species | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others |
Picroside II (Vanilloyl catalpol) 是从胡黄连提取的一种环烯醚萜类,有神经保护作用,具有抗氧化、抗炎、抗细胞凋亡、免疫调节和抗病毒等药理活性。 | |||
T4733 |
Sucrose
D(+)-Sucrose,D-(+)-Saccharose,蔗糖 |
Others; Endogenous Metabolite | Metabolism; Others |
Sucrose (D-(+)-Saccharose) 是一种二糖,由果糖和葡萄糖组成。Sucrose 能够应用于一些动物模型,包括代谢性疾病、偏食、肥胖、糖尿病等。 | |||
T21977 |
p-Cresyl sulfate
|
Others | Others |
p-Cresyl Sulfate 是主要的尿毒症毒素,存在于慢性肾病患者的血液,来源于肝脏中酪氨酸和苯丙氨酸的代谢物。 | |||
T3A2467 |
Allocryptopine
Thalictrimine,Fagarine I,别隐品碱 |
Potassium Channel | Membrane transporter/Ion channel |
Allocryptopine (Thalictrimine) 是一种延胡索乙素的衍生物,提取自Corydalis decumbens。Allocryptopine 具有抗心律失常作用,能有效阻断hERG 电流。 | |||
T3859 |
Isomucronulatol
7,2'-Dihydroxy-3',4'-dimethoxyisoflavan,7,2'-二羟基-3',4'-二甲氧基异黄烷,异短尖剑豆酚 |
Others | Others |
Isomucronulatol (7,2'-Dihydroxy-3',4'-dimethoxyisoflavan) 是一种黄酮类化合物,分离自 A. membranaceus 根。它在体外对 LPS 刺激产生的 IL-12 p40 有抑制作用,具有潜在的抗炎作用。 | |||
TN6837 |
Syringopicroside
2-(4-hydroxyphenyl)ethyl (1S,4aS,7R)-7-methyl-6-oxo-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carboxylate |
Others | Others |
Syringopicroside (2-(4-hydroxyphenyl)ethyl (1S,4aS,7R)-7-methyl-6-oxo-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carboxylate) 是一种来自 Syringa oblata Lindl (S. oblata) 的具有抗菌活性的天然药物。 | |||
T13557 |
Ascr#5
Ascaroside C3 |
Others | Others |
Ascr#5 (asc-ωC3)是秀丽隐杆线虫中高度保守的蛔苷类物质,可调节秀丽隐杆线虫的多种反应。 | |||
TN1159 |
(1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one
[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one |
Others | Others |
(1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one ([(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one) 是一种来自姜黄的倍半萜。 | |||
T6S0033 |
Crotonoside
巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE |
Others; FLT; HDAC | Angiogenesis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others; Tyrosine Kinase/Adaptors |
Crotonoside (Isoguanosine) 是从中草药巴豆中分离出来的一种天然产物。 它抑制 FLT3 和 HDAC3/6,有治疗急性髓性白血病 (AML)的研究潜力。 | |||
TN4494 |
Maoecrystal B
|
Others | Others |
Maoecrystal B 是一种分离自 Isodon eriocalyx var.叶子的二萜化合物。 | |||
T5703 |
β,β-Dimethylacrylalkannin
|
Others | Others |
β,β-Dimethylacrylalkannin 是一种萘醌类化合物,分离自紫草属植物中,可以提高皮肤细胞中胶原蛋白和内披蛋白的含量。 | |||
T3S0209 |
Vincristine
|
ERK; p38 MAPK; NF-κB; Akt; JNK; mTOR | Cytoskeletal Signaling; MAPK; NF-κB; PI3K/Akt/mTOR signaling |
Vincristine 与微管蛋白结合并抑制微管的形成,从而抑制癌细胞的有丝分裂。 Vincristine 可用作微管去稳定剂,用于研究治疗血液系统癌症,如白血病和淋巴瘤以及儿童肉瘤的相关研究。 | |||
T2803 |
Monocrotaline
野百合碱,Crotaline |
TGF-beta/Smad | Stem Cells |
Monocrotaline (Crotaline) 是一种吡咯里西啶生物碱,从猪屎豆植物的种子中提取得到,可诱导啮齿动物产生肺动脉高血压。 | |||
T20446 |
Creosol
|
Endogenous Metabolite | Metabolism |
Creosol 是内源性代谢产物的一种。 | |||
TN7122 |
Micromarin F
E-Methylarnottinin,5'-hydroxylosthole |
Others | Others |
Micromarin F (E-Methylarnottinin) 是从 Micromelum minutum Wight et Arn 的茎中提取的香豆素衍生物。 | |||
T19412 |
Macrozamin
甲基氧化偶氮甲醇樱草糖苷,大泽明素 |
Others | Others |
Macrozamin 是苏铁的一种主要成分,表现出致癌,致畸,诱变和神经毒性作用。 | |||
T15753 |
Licraside
Licuraside |
Tyrosinase | Proteases/Proteasome |
Licraside 是一种酪氨酸酶抑制剂,对单酚酶的 IC50 为 0.072 mM,可用于抗褐变和脱色剂的研究。 | |||
T4S0171 |
Transcrocetin
trans-Crocetin,藏红花酸,藏红花,8,8'-Diapocarotenedioic Acid,Crocetin |
Others; Endogenous Metabolite; iGluR | Membrane transporter/Ion channel; Metabolism; Neuroscience; Others |
Transcrocetin (8,8'-Diapocarotenedioic Acid) 是来源于藏红花 (Crocus sativus L.) 的活性化合物,是一种能够透过血脑屏障的,高亲和力的NMDA 受体拮抗剂。 | |||
TN2069 |
Picrocrocin
藏红花,苦番紅花素 |
Apoptosis | Apoptosis |
Picrocrocin 是一种从椰菜花中发现的类胡萝卜素,对 SKMEL-2 人恶性黑色素瘤细胞具有生长抑制作用,具有抗癌作用。 | |||
T6943 |
Picropodophyllin
AXL1717,苦鬼臼脂素,Picropodophyllin (PPP),Picropodophyllotoxin,PPP,苦鬼臼毒素 |
Apoptosis; IGF-1R | Apoptosis; Tyrosine Kinase/Adaptors |
Picropodophyllin (Picropodophyllin (PPP)) 是一种选择性的胰岛素样生长因子-1受体抑制剂,IC50为1 nM。 | |||
TN1787 |
Isomucronulatol 7-O-glucoside
Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷 |
Others | Others |
Isomucronulatol 7-O-glucoside 具有潜在的抗炎活性,在体外对 LPS 刺激产生的 IL-12 p40 表现出微弱的抑制作用。 | |||
T19433 |
Monocrotaline N-Oxide
野百合碱N-氧化物,野百合碱 N-氧化物 |
Others | Others |
Monocrotaline N-Oxide 是一种野百合碱代谢物,能够促进体内形成DNA 加合物。 | |||
T1399 |
Sucralose
Trichlorosucrose,三氯蔗糖,E955 |
Others; Endogenous Metabolite | Metabolism; Others |
Sucralose (Trichlorosucrose) 是一种无营养的人工甜味剂 (sweetener) 和代糖,它能够激活保守神经的禁食响应,从而刺激啮齿动物产生食欲。 | |||
T4888 |
Phosphocreatine disodium hydrate
磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Phosphocreatine disodium hydrate 是内源性代谢产物的一种。 | |||
T4739 |
Sodium creatine phosphate dibasic tetrahydrate
磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) 主要存在于脊椎动物的骨骼肌中,是测定肌酸激酶的底物,能够用于骨骼肌收缩过程中 ATP 的再生。 | |||
T3367 |
Macranthoidin B
灰毡毛忍冬皂苷乙,金银花,Macranthoiside I |
Others | Others |
Macranthoidin B (Macranthoiside I) 是一种活性天然皂苷。 | |||
TQ0027 |
Transcrocetinate disodium
Disodium trans-crocetinate,藏红花,藏红花酸二钠盐 |
NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
Transcrocetinate disodium (Disodium trans-crocetinate) 从藏红花中提取的一种天然产物,是高亲和力NMDA 受体拮抗剂。 | |||
T20879 |
Tacrolimus monohydrate
FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,他克莫司一水合物,FK 506 |
Phosphatase; Others; Antibacterial; Antibiotic; Autophagy | Autophagy; Metabolism; Microbiology/Virology; Others |
Tacrolimus monohydrate (LCP-Tacro) 是大环内酯类化合物,它与 FK506 结合蛋白 (FKBP) 结合形成复合物并抑制钙调神经磷酸酶,从而抑制 T 淋巴细胞信号转导和 IL-2 转录。具有强免疫抑制特性。 | |||
TN2070 |
Picropodophyllol
|
Others | Others |
Picropodophyllol 是从 Dysosma versipellis 的根中分离出来的天然产物。 | |||
TN7113 |
Methacrylamide
|
Others | Others |
Methacrylamide 是一种具有染色性的天然产物。 | |||
TN1831 |
Macranthoside A
Kalopanaxsaponin H |
Antioxidant | oxidation-reduction |
Macranthoside A (Kalopanaxsaponin H) 是一种从地黄中提取的三萜糖苷,属于环烯醚萜类化合。Macranthoside A 具有抗炎、抗氧化、抗菌和神经保护活性,抑制促炎细胞因子的产生和抑制炎症信号通路的激活,有助于中和有害的自由基,保护细胞免受氧化损伤,可以促进神经元的存活和生长,并防止氧化应激或神经毒性化合物引起的神经元细胞死亡,具有治疗神经退行性疾病、心血管疾病和肝损伤的潜力。 | |||
TN2068 |
Picrinine
|
Lipoxygenase | Metabolism |
Picrinine 是一种从 Alstonia scholaris 的叶子中提取出来的 Akuammiline 生物碱。 Picrinine 具有抗炎活性,通过抑制5-脂氧合酶来发挥作用。 | |||
T5771 |
Hypocrellin A
|
Antibacterial; PKC; Parasite | Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology |
Hypocrellin A 是一种天然的PKC 抑制剂,具有光诱导的抗肿瘤、抗真菌和抗病毒活性,还对 MHC 限制性抗原呈递发挥免疫调节作用。 | |||
T0496 |
Creatinine
肌酸酐,NSC13123 |
Endogenous Metabolite | Metabolism |
Creatinine (NSC-13123) 由肌肉中磷酸肌酸分解产生。 | |||
T5780 |
HYPOCRELLIN B
|
Apoptosis; Parasite; Antifungal | Apoptosis; Microbiology/Virology |
Hypocrellin B 是从真菌Hypocrella bambusae 和Shiraia bambusicola 中分离得到的一种感光颜料,可用于癌症光动力研究。它是一个凋亡诱导剂,还拥有抗菌和抗利什曼活性。 | |||
TN1429 |
Bancroftinone
1-(6-羟基-2,4-二甲氧基-3-甲基苯基)乙酮,母丁香酚 |
Others | Others |
Bancroftinone 是一种烷基苯酮类天然产物。 | |||
TN2071 |
Picropodophyllone
(-)-Picropodophyllone,Picropodopyllotoxone,苦鬼臼脂毒酮 |
Others | Others |
Picropodophyllone 是一种从Podophyllum hexandrum 的叶子中分离出来的芳基四氢呋喃木脂素,具有抗真菌活性。 | |||
T2945 |
Germacrone
|
P450; Antiviral; Influenza Virus | Immunology/Inflammation; Metabolism; Microbiology/Virology |
Germacrone 提取自姜黄,具有抗炎、抗雄激素和抗病毒活性。 它还通过促进细胞凋亡来抑制胶质瘤细胞的增殖。 | |||
T5S0733 |
Picroside III
|
Others | Others |
Picroside III(胡黄连苷 III)是一种环烯醚萜苷,分离自传统中药胡黄连中。 | |||
T3S2344 |
β,β-Dimethylacrylshikonin
β,β-二甲基丙烯酰紫草素,Dimethylacrylshikonin,β, β-Dimethylacrylshikonin |
ERK; HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; MAPK; Metabolism |
β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) 是一种萘醌衍生物,从 Arnebia nobilis 中提取得到。它利用 PI3K 通路诱导 eNOS、VEGF 和 HIF-1α 的表达,促进血管生成,具有抗肿瘤活性。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01413 |
Cripto Protein, Human, Recombinant (His)
CR,CRIPTO,teratocarcinoma-derived growth f... |
Human | HEK293 Cells |
Cripto Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is AAH22393.1. | |||
TMPK-00073 |
TDGF1/Cripto Protein, Human, Recombinant (His)
TDGF1,Cripto,CR,CRGF |
Human | HEK293 Cells |
TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involve... | |||
TMPY-05503 |
Cripto Protein, Human, Recombinant (hFc)
teratocarcinoma-derived growth factor 1,CR,CR |
Human | HEK293 Cells |
Cripto Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is P13385. | |||
TMPK-00550 |
CD55/DAF Protein, Cynomolgus, Recombinant (His)
TC,DAF-GPI,CR,CROM,Daf1,CD55,Cd55a,DAF |
Cynomolgus | HEK293 Cells |
Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection. | |||
TMPY-00713 |
CD55/DAF Protein, Human, Recombinant (hFc)
CR,CD55 molecule, decay accelerating factor for com... |
Human | HEK293 Cells |
CD55/DAF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.7 kDa and the accession number is P08174-1. | |||
TMPY-01292 |
CD55/DAF Protein, Human, Recombinant (His)
CD55 molecule, decay accelerating factor for complement ( |
Human | HEK293 Cells |
CD55/DAF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P08174-1. | |||
TMPH-02606 |
CR1L Protein, Mouse, Recombinant (His)
Crry,Complement regulatory protein Crry,Co... |
Mouse | E. coli |
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. CR1L Prot... | |||
TMPH-01135 |
CR1 Protein, Human, Recombinant (GST)
Complement receptor type 1,C3b/C4b receptor,C3BR,CD35,CR... |
Human | E. coli |
CR1 Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPK-00842 |
CD21 Protein, Human, Recombinant (His)
CD21,CR2,C3DRSLEB9,EBV receptor,CVID7,SLEB9,C3DR |
Human | HEK293 Cells |
CD21 mRNA expression, an EBV-entry receptor, was transiently detected in NK cells after exosome treatment, and levels decreased after further culture. CD21 protein expression was also transiently transferred to NK cells after co-culture with an EBV-positive Burkitt lymphoma cell line (Raji) via trogocytosis. However, EBV did not infect NK cells through CD21-mediated trogocytosis. | |||
TMPK-00840 |
CD21 Protein, Mouse, Recombinant (His)
C3DRSLEB9,CR2,CVID7,C3DR,CD21,SLEB9,EBV receptor |
Mouse | HEK293 Cells |
A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes. | |||
TMPY-03655 |
GADD45G Protein, Human, Recombinant
GADD45γ,growth arrest and DNA-damage-inducible, γ,DDIT2,grow... |
Human | E. coli |
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G reacts to environmental stresses by mediating activation of the p38/JNK pathway which is mediated through their protein binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. GADD45G acts as a new-age tumor suppressor however is being fr... | |||
TMPJ-00711 |
GADD45G Protein, Human, Recombinant (His)
Cytokine-Responsive Protein CR6,Growth Arrest and D... |
Human | E. coli |
Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apo... | |||
TMPY-05242 |
CRLF2/TSLPR Protein, Human, Recombinant (His)
CRL2,CRLF2Y,TSLPR,cytokine receptor-like f... |
Human | HEK293 Cells |
CRLF2/TSLPR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is D0E2W4. | |||
TMPY-04616 |
NKp30/NCR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
natural cytotoxicity triggering receptor 3 |
Cynomolgus,Rhesus | HEK293 Cells |
NKp30/NCR3 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.3 kDa and the accession number is XP_005553604.1. | |||
TMPY-01145 |
NKp30/NCR3 Protein, Human, Recombinant (His)
NCR3,natural cytotoxicity triggering receptor 3,CD3... |
Human | HEK293 Cells |
NKp30/NCR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.4 kDa and the accession number is O14931-1. | |||
TMPY-05511 |
NKp46/NCR1 Protein, Mouse, Recombinant (His)
NKp46,Ly94,natural cytotoxicity triggering receptor 1 |
Mouse | HEK293 Cells |
NKp46/NCR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is A0A0R4IZY7. | |||
TMPY-01373 |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is I6TSC9. | |||
TMPY-01807 |
NKp44/NCR2 Protein, Human, Recombinant (His)
RP1-149M18.2,LY95,dJ149M18.1,NK-p44,CD336,natural cytotoxici... |
Human | HEK293 Cells |
NKp44/NCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is O95944-1. | |||
TMPY-01686 |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)
β-2 microglobulin,beta-2 microglobulin |
Human | HEK293 Cells |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P61769. | |||
TMPY-00856 |
TCCR Protein, Human, Recombinant (hFc)
WSX1,interleukin 27 receptor, α,IL27R,TCCR,IL-27RA,... |
Human | HEK293 Cells |
TCCR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79 kDa and the accession number is Q6UWB1. | |||
TMPY-05346 |
CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)
SpyCas9 |
Streptococcus pyogenes | Baculovirus Insect Cells |
CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 163 kDa and the accession number is Q99ZW2. | |||
TMPK-00114 |
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
C-reactive protein,MGC88244,PTX1MGC149895,CRP,pentr... |
Human | HEK293 Cells |
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactiv... | |||
TMPY-01813 |
ACRV1 Protein, Human, Recombinant (His)
SP-10,SPACA2,D11S4365,acrosomal vesicle protein 1 |
Human | HEK293 Cells |
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest tr... | |||
TMPY-05227 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
TIMD3,hepatitis A virus cellular receptor 2,CD366,KIM-3,TIMD... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPY-04722 |
DcR1/TRAILR3 Protein, Human, Recombinant (His)
TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR... |
Human | HEK293 Cells |
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC. | |||
TMPH-00007 |
HMGCR Protein, Human, Recombinant (His)
|
Human | E. coli |
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs. | |||
TMPY-02882 |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His)
CUB domain containing protein 1 |
HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.2 kDa. | |||
TMPY-01621 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
TIMD-3,hepatitis A virus cellular receptor 2,HAVcr-... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPK-00190 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His)
KIM3,TIM3,TIM 3,TIMD-3,HAVCR2, FLJ14428,CD366,TIM-3 |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 20.7 kDa and the accession number is Q8TDQ0-1. | |||
TMPK-00879 |
CCR2b Protein-VLP, Human, Recombinant
C-C CKR-2,CCR2,MCP-1-R,CCR-2,CMKBR2 |
Human | HEK293 Cells |
The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane stru... | |||
TMPJ-01236 |
B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)
Beta-2-Microglobulin,β-2-Microglobulin,B2M |
Cynomolgus | HEK293 Cells |
B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 14 KDa and the accession number is Q8SPW0. | |||
TMPK-00091 |
NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated
1C7,LY117,CD337,NKp30,MALS,NCR3 |
Human | HEK293 Cells |
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. | |||
TMPY-06884 |
SARS-CoV-2 XBB.1.9.1 (Omicron) Spike S1+S2 trimer Protein (His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 XBB.1.9.1 (Omicron) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.74 kDa and the accession number is YP_009724390.1. | |||
TMPY-06890 |
SARS-CoV-2 XBB.1.16 (Omicron) Spike S1 Protein (His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 XBB.1.16 (Omicron) Spike S1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa. | |||
TMPY-06625 |
SARS-COV-2 BF.7 (Omicron) Nucleoprotein/NP Protein (His)
|
SARS-CoV-2 | E. coli |
SARS-COV-2 BF.7 (Omicron) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession number is YP_009724397.2. | |||
TMPK-00546 |
TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)
CD365,HAVCR1,KIM1,TIMD-1,TIM-1,KIM-1,HAVcr... |
Cynomolgus | HEK293 Cells |
Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation. TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 35.25 kDa and the accession number is ... | |||
TMPY-06335 |
SARS-CoV-2 B.1.1.529 sublineage BA.2 (Omicron) Spike RBD Protein (His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 B.1.1.529 sublineage BA.2 (Omicron) Spike RBD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.71 kDa and the accession number is YP_009724390.1. | |||
TMPY-06369 |
SARS-CoV-2 BA.2.75.2 (Omicron) Spike S1+S2 trimer Protein (His)
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SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 BA.2.75.2 (Omicron) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.41 kDa and the accession number is YP_009724390.1. | |||
TMPY-03521 |
DcR3 Protein, Human, Recombinant (hFc)
DCR3,tumor necrosis factor receptor superf... |
Human | Baculovirus Insect Cells |
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tu... | |||
TMPY-04272 |
FcRH2/FCRL2 Protein, Human, Recombinant (His)
IFGP4,FCRH2,CD307b,SPAP1,SPAP1B,Fc receptor like 2,... |
Human | HEK293 Cells |
Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia). | |||
TMPY-06296 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
HAVcr-2,KIM-3,TIM3,CD366,HAVCR2,hepatitis ... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 48.41 kDa and the accession number is Q8TDQ0-1. | |||
TMPY-06350 |
SARS-CoV-2 B.1.1.529 (Omicron) S1+S2 trimer Protein (His & Avi), Biotinylated
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 B.1.1.529 (Omicron) S1+S2 trimer Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 138.48 kDa and the accession number is YP_009724390.1. | |||
TMPH-00392 |
Small-CRP Protein, Chlamydia trachomatis, Recombinant (His & SUMO)
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Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplasmic protein and the major outer membrane porin. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. Small-CRP Protein, Chlamydia trachomatis, Recombinant (His & SUMO) is... | |||
TMPK-00761 |
B2M/beta 2-Microglobulin Protein, Mouse, Recombinant (hFc)
B2M/β 2-Microglobulin,Beta-2-microglobulin... |
Mouse | HEK293 Cells |
The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors. | |||
TMPJ-01422 |
CRTAM Protein, Cynomolgus, Recombinant (His)
Cytotoxic and Regulatory T-Cell Molecule,CD355,CRTA... |
Cynomolgus | HEK293 Cells |
CRTAM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-60 KDa and the accession number is XP_005580021.1. | |||
TMPH-02455 |
Acrosin Protein, Meleagris gallopavo, Recombinant (His & Myc)
EC:3.4.21.10,Proacrosin,Proacro1 |
Meleagris gallopavo | E. coli |
Serine protease of trypsin-like cleavage specificity. Synthesized in a zymogen form, proacrosin and stored in the acrosome. Acrosin Protein, Meleagris gallopavo, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.1 kDa and the accession number is Q2UVH8. | |||
TMPH-02887 |
SCRG1 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
N/A. SCRG1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.0 kDa and the accession number is O88745?. | |||
TMPH-00180 |
Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO)
Pesticidal crystal protein Cry1Ab,Insectic... |
Bacillus thuringiensis subsp. kurstaki | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.3 kDa and the accession number is P0A370. | |||
TMPY-06615 |
SARS-CoV-2 XBB (Omicron) Spike S1+S2 trimer Protein (His)
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SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 XBB (Omicron) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.26 kDa and the accession number is YP_009724390.1. | |||
TMPH-00550 |
Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc)
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EBV | E. coli |
Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. Inhibits IFN-gamma synthesis. Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted m... | |||
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