β-/γ-secretase inhibitor kit 包含β-/γ-分泌酶抑制剂,β-secretase 是以 BACE1 为活性中心,Aph-1、Pen-2、nicastrin 的复合体;γ-secretase 是以 presenilin1 或 presenilin2 为活性中心的,与 Aph-1、Pen-2、nicastrin 组成的复合体,主要参与β-淀粉样蛋白前体(APP)和Notch 等重要跨膜蛋白的切割和水解过程。TargetMol 为您提供38种精选β-/γ-分泌酶抑制剂。所有化合物现货供应,到货快捷,是您预实验探索的不二选择。
ID | Compound | CAS | MW | Concentration | Target |
---|---|---|---|---|---|
T2262 | Itanapraced | 749269-83-8 | 325.16 | 10mM | Beta Amyloid; Gamma-secretase |
T2625 | MK-0752 | 471905-41-6 | 442.9 | 10mM | Beta Amyloid; Gamma-secretase |
T2639 | LY2811376 | 1194044-20-6 | 320.36 | 10mM | BACE; Beta Amyloid; Beta-secretase |
T3285 | Eslicarbazepine Acetate | 236395-14-5 | 296.32 | 10mM | Beta-secretase; Sodium Channel |
T3633 | Crenigacestat | 1421438-81-4 | 464.44 | 10mM | Gamma-secretase |
T3769 | Tenuifolin | 20183-47-5 | 680.37 | 10mM | AChE; Beta-secretase |
T4398 | LX2343 | 333745-53-2 | 474.91 | 10mM | Autophagy; BACE; Beta Amyloid; Beta-secretase; PI3K |
T6058 | LY2886721 | 1262036-50-9 | 390.41 | 10mM | BACE; Beta-secretase |
T6063 | LY-411575 | 209984-57-6 | 479.48 | 10mM | Apoptosis; Gamma-secretase |
T6125 | Semagacestat | 425386-60-3 | 361.44 | 10mM | Beta Amyloid; Gamma-secretase |
T6135 | YO-01027 | 209984-56-5 | 463.48 | 10mM | Gamma-secretase |
T6202 | DAPT | 208255-80-5 | 432.46 | 10mM | Apoptosis; Autophagy; Beta Amyloid; Gamma-secretase |
T6249 | Avagacestat | 1146699-66-2 | 520.88 | 10mM | Gamma-secretase |
T6274 | RO4929097 | 847925-91-1 | 469.4 | 10mM | Beta Amyloid; Gamma-secretase |
T6772 | AZD3839 free base | 1227163-84-9 | 431.41 | 10mM | BACE; Beta-secretase |
T6870 | L-685458 | 292632-98-5 | 672.85 | 10mM | Apoptosis; Gamma-secretase |
T6935 | Nirogacestat | 1290543-63-3 | 489.64 | 10mM | Apoptosis; Gamma-secretase |
T7011 | Verubecestat | 1286770-55-5 | 523.43 | 10mM | BACE; Beta-secretase |
T2S1181 | Aloenin | 38412-46-3 | 410.37 | 10mM | AChR; Beta-secretase |
T5S2361 | Epiberberine | 6873-09-2 | 336.36 | 10mM | AChE; AChR; BACE; Beta-secretase; ERK; MEK |
T8179 | Aloeresin D | 105317-67-7 | 556.6 | 10mM | BACE; Beta-secretase |
T15184 | E 2012 | 870843-42-8 | 419.49 | 10mM | Gamma-secretase |
T9015 | LY900009 | 209984-68-9 | 409.49 | 10mM | Gamma-secretase |
T16294 | NGP555 | 1304630-27-0 | 406.52 | 10mM | Gamma-secretase |
T11175 | Elenbecestat | 1388651-30-6 | 437.44 | 10mM | BACE; Beta-secretase |
T22678 | 3,5-Bis(4-nitrophenoxy)benzoic acid | 173550-33-9 | 396.31 | 10mM | Gamma-secretase |
T21890 | JLK6 | 62252-26-0 | 225.63 | 10mM | Gamma-secretase |
T9422 | Fosciclopirox | 1380539-06-9 | 317.27 | 10mM | Gamma-secretase |
T16133 | MRK-560 | 677772-84-8 | 517.92 | 10mM | Gamma-secretase |
T3285L | Eslicarbazepine | 104746-04-5 | 254.28 | 10mM | Beta-secretase; sodium channel |
T11358 | gamma-secretase modulator 1 | 1172637-87-4 | 416.54 | 10mM | Gamma-secretase |
T11178L | ELN318463 racemate | 851599-82-1 | 471.8 | 10mM | Gamma-secretase |
T2759 | Loganin | 18524-94-2 | 390.38 | 10mM | AChE; AChR; Apoptosis; BACE; NF-κB |
T3394 | Timosaponin BII | 136656-07-0 | 920.07 | 10mM | BACE; Beta Amyloid |
TN1343 | 8-Geranyloxypsoralen | 7437-55-0 | 338.4 | 10mM | Anti-infection; BACE; P450 |
T3161L | BACE-IN-1 acetate | T3161L | 1711.86 | 10mM | BACE |
T12188 | NB-360 | 1262857-73-7 | 449.4 | 10mM | BACE |
T13253 | Umibecestat | 1387560-01-1 | 513.8 | 10mM | BACE |