1189
53
13
91
80
Cat. No. | Product Name | ||
---|---|---|---|
L1100 | 蛋白酶抑制剂库 | 343 compounds | |
343 种已知的小分子蛋白酶抑制剂的特有集合,可用于高通量筛选和高内涵筛选; | |||
L1400 | MAPK 抑制剂库 | 365 compounds | |
365 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合,可用于高通量筛选和高内涵筛选; | |||
L2200 | 酪氨酸激酶分子库 | 1016 compounds | |
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L9400 | PPI抑制剂库 | 485 compounds | |
485 种已知活性的 PPI 相关的抑制剂,可用于高通量、高内涵筛选; | |||
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L1600 | 激酶抑制剂库 | 2700 compounds | |
2700 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L2000 | 抑制剂库 | 8328 compounds | |
8328 个小分子抑制剂的独特集合,主要用于细胞信号研究、新药筛选、高通量筛选和高内涵筛选; | |||
L9100 | 磷酸酶抑制剂化合物库 | 79 compounds | |
79 种已知活性的磷酸酶抑制剂的集合,可用于化合物筛选、化学基因组学、药理分析等方面; | |||
L2010 | 高选择性抑制剂库 | 575 compounds | |
575种具有高选择性的抑制剂集合 | |||
L1610 | FDA 上市激酶抑制剂库 | 263 compounds | |
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L3600 | 细胞因子抑制剂库 | 604 compounds | |
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体; | |||
L9410 | 共价抑制剂库 | 1920 compounds | |
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发; | |||
L2300 | 离子通道库 | 931 compounds | |
931 种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26828 |
BIT225
BIT 225,BIT-225 |
||
BIT-225 is a NCp7 zinc finger inhibitor. BIT225 inhibits HIV-1 replication in myeloid dendritic cells. BIT225 inhibits HIV-1 release from human macrophages. BIT225 inhibits bovine viral diarrhea virus in vitro and shows synergism with recombinant interfer | |||
T22195 |
CBFβ Inhibitor
5-乙基-4-(4-甲氧基苯基)-1,3-噻唑-2-胺,5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) 是一种细胞渗透性 CBFβ 抑制剂,可抑制其与 Runx1 的结合。 | |||
T1383 |
Bitoscanate
p-Phenylene diisothiocyanate,对苯二异硫氰酸酯,Biscomate,PDITC,1,4-Diisothiocyanatobenzene |
Parasite | Microbiology/Virology |
Bitoscanate (PDITC) 是一种抗钩虫剂。 | |||
T3593 |
Src Inhibitor 1
Src Kinase Inhibitor 1,Src-l1 |
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
Src Inhibitor 1 (Src Kinase Inhibitor 1) 是一种选择性的、高效的、ATP-竞争性的双位点 Src 酪氨酸激酶抑制剂,能够抑制 Src (IC50:44 nM) 和 Lck (IC50:88 nM)。 | |||
T4656 |
RAD51 Inhibitor B02
B02 |
Apoptosis; DNA/RNA Synthesis | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
RAD51 Inhibitor B02 (B02) 是一种人 RAD51的抑制剂,IC50值为27.4 μM。 | |||
T6409 |
ALK kinase inhibitor-1
SAR348830 |
Others | Others |
SAR348830 是间变性淋巴瘤激酶ALK 抑制剂。 | |||
T10629 |
Btk inhibitor 2
BGB-3111 analog |
BTK | Angiogenesis; Tyrosine Kinase/Adaptors |
Btk inhibitor 2 (BGB-3111 analog) 是一种布鲁顿酪氨酸激酶 (BTK) 抑制剂。 | |||
T15654 |
Ketohexokinase inhibitor 1
PF-06835919 |
Others | Others |
Ketohexokinase inhibitor 1 是一种酮己糖激酶抑制剂(对 KHK-C 和 KHK-A 的 IC50:分别为 8.4 nM 和 66 nM)。 | |||
T83627 |
Pim-1 kinase inhibitor 8
|
Pim; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling |
Pim-1 kinase inhibitor 8 是一种高效的 Pim-1 kinase 抑制剂,具有抗癌活性,可有效抑制细胞迁移。Pim-1 kinase inhibitor 8 对 MCF-7 和 HepG2 细胞有细胞毒性,是研究乳腺癌的候选化合物。 | |||
T9068 |
Cucurbit[7]uril
|
Others | Others |
Cucurbit[7]uril 是一种新兴的药用辅料候选物。Cucurbit[7]uril 可增强神经母细胞瘤细胞中卟啉的光敏作用。 | |||
T11467 |
GSK-3β inhibitor 1
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 1 是一种糖原合成酶激酶 3β (GSK-3β)的抑制剂,其 IC50=4.9 nM,可用于糖尿病的研究。 | |||
T28804 |
Slingshot inhibitor D3
JHN76359 |
Others | Others |
Slingshot inhibitor D3 (JHN76359) 是具有选择性、竞争性、可逆性的Slingshot 抑制剂。它对Slingshot 1和Slingshot 2具有相似的抑制活性。它对Slingshot 1 的IC50为 3 μM;对Slingshot 2 的Ki 为 3.9 μM。 | |||
T5831 |
Selective PI3Kδ Inhibitor 1
|
PI3K | PI3K/Akt/mTOR signaling |
Selective PI3Kδ Inhibitor 1 是一种 PI3Kδ 抑制剂 (IC50 = 0.9 nM)。 | |||
T7265 |
HSP27 inhibitor J2
J2 |
HSP | Cytoskeletal Signaling; Metabolism |
HSP27 inhibitor J2 (J2) 是一种HSP27抑制剂,可显著增强 17-AAG 的抗增殖活性,并对顺铂诱导的肺癌细胞生长抑制具有敏感性。它显著诱导异常 HSP27 二聚体形成并抑制HSP27巨聚合物的产生,从而具有抑制HSP27的伴侣功能和降低细胞保护功能的作用。 | |||
T9854 |
HIV-1 inhibitor-6
3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) 是一种有效的HIV-1 pre-mRNA 选择性剪接抑制剂,可以阻断HIV 复制。 | |||
T4348 |
Syk Inhibitor II
|
5-HT Receptor; Syk | Angiogenesis; GPCR/G Protein; Neuroscience; Tyrosine Kinase/Adaptors |
Syk Inhibitor II 是一种可渗透细胞、具有 ATP 竞争性的嘧啶-甲酰胺化合物,可选择性且可逆地抑制 Syk,IC50为 41 nM。 | |||
T10678 |
Carboxypeptidase G2 (CPG2) Inhibitor
CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor |
Carboxypeptidase | Proteases/Proteasome |
Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) 是新型的羧肽酶 G2(CPG2)抑制剂,显示出抗癌活性。 | |||
T67944 |
p38 MAP Kinase Inhibitor Ⅵ
|
p38 MAPK | MAPK |
p38 MAP Kinase Inhibitor Ⅵ是一种有效的p38 MAP Kinase 抑制剂,具有抗炎活性。 | |||
T35554 |
GSK-3β inhibitor 3
|
Apoptosis; GSK-3 | Apoptosis; PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 3 是一种糖原合成酶激酶 3β(GSK-3β)共价抑制剂 ( IC50 : 6.6 μM),具有强效性、选择性和不可逆性。GSK-3β inhibitor 3 可用于研究急性早幼粒细胞白血病。 | |||
T16868 |
SEC inhibitor KL-2
KL-2 |
Others | Others |
SEC inhibitor KL-2 (KL-2) (KL-2) 是一种拟肽先导化合物,有效的选择性 SEC 抑制剂,通过破坏 SEC 支架蛋白 AFF4 和 P-TEFb 之间的相互作用,导致 Pol II 从启动子近端暂停位点的释放受损并且进行性转录延伸的平均速率降低。SEC inhibitor KL-2 剂量依赖性地抑制 AFF4-CCNT1 相互作用,Ki 值为 1.50 μM。 | |||
T61318 |
BRD4 Inhibitor-20
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
BRD4 Inhibitor-20是一种有效的溴结构域蛋白4(BRD4)抑制剂,具有口服活性。BRD4 Inhibitor-20在癌细胞系中具有抗增殖活性,并被用于各种癌症的研究,如结肠癌。 | |||
T5338 |
mTOR inhibitor-1
|
mTOR; Autophagy | Autophagy; PI3K/Akt/mTOR signaling |
mTOR inhibitor-1是一种新型 ATP 竞争性 mTOR 抑制剂,可抑制细胞生长和增殖,诱导自噬。 | |||
T2457 |
IRAK-1-4 Inhibitor I
IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor |
IRAK | Immunology/Inflammation; NF-κB |
IRAK-1-4 Inhibitor I 是一种IRAK1/4双重抑制剂,其IC50分别为 0.2 μM 和 0.3 μM。 | |||
T5110 |
IRAK inhibitor 6
|
IRAK | Immunology/Inflammation; NF-κB |
IRAK inhibitor 6 是白细胞介素-1受体相关激酶-4的抑制剂(IC50:160 nM)。 | |||
T75888 |
PKA Inhibitor Fragment (6-22) amide TFA
PKI-(6-22)-amide TFA,PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base) |
PKA | Tyrosine Kinase/Adaptors |
PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) 是抑制高效 cAMP 依赖性蛋白激酶 A (PKA)抑制剂(Ki:2.8 nM)。PKA Inhibitor Fragment (6-22) amide TFA 可逆转小鼠低水平的吗啡缓解疼痛的作用。 | |||
T60454 |
NDM-1 inhibitor-3
|
Others | Others |
NDM-1 inhibitor-3 是一种广泛存在于自然界中的 New Delhi Metallo-β-lactamase-1 (NDM-1) 抑制剂(Ki : 4 μM),与抗生素耐药有关。 | |||
T60087 |
cFMS Receptor Inhibitor IV
5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide |
c-Fms | Tyrosine Kinase/Adaptors |
cFMS Receptor Inhibitor IV 是 c-Fms 酪氨酸激酶的抑制剂。 | |||
T27066 |
Prostaglandin G/H synthase 1 inhibitor
CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide |
Others | Others |
Prostaglandin G/H synthase 1 inhibitor (CP 74006) 是一种选择性D5D 抑制剂,IC(50)值为20nM。 | |||
T67755 |
Protein kinase G inhibitor-1
|
PKA | Tyrosine Kinase/Adaptors |
Protein kinase G inhibitor-1是有效的蛋白激酶G 抑制剂,IC50= 0.9 uM。 | |||
T60358 |
sEH inhibitor-7
|
Epoxide Hydrolase | Metabolism |
sEH inhibitor-7是一种可溶性环氧化物水解酶(sEH)抑制剂,对人和小鼠的 sEH 有抑制作用,IC 50 s 分别为 6.2 μM 和0.15 μM 。sEH inhibitor-7与抗炎活性分子有关。 | |||
T21512 |
MMP-2/MMP-9 Inhibitor I
|
MMP | Proteases/Proteasome |
MMP-2/MMP-9-IN-1 是一种有效的、具有高选择性和可口服的 IV 型胶原酶 (MMP-9和MMP-2) 抑制剂,对 MMP-9 和 MMP-2具有抑制作用, IC50分别为 0.24 和 0.3 1μM。MMP-2/MMP-9-IN-1 在肿瘤生长和转移的动物模型中展现出口服活性,可用于研究癌症。 | |||
T78578 |
GSK-3 Inhibitor XIII
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3 Inhibitor XIII,一种ATP竞争性的 GSK-3抑制剂(Ki:24 nM),可用于研究糖尿病和肥胖。 | |||
T35529 |
hSMG-1 inhibitor 11e
|
Others | Others |
hSMG-1 inhibitor 11e 是一种有效的选择性 hSMG-1 抑制剂 (IC50 <0.05 nM),可用于癌症治疗研究。 | |||
T12728 |
RIP2 Kinase Inhibitor 3
|
Others; RIP kinase | Apoptosis; NF-κB; Others |
RIP2 Kinase Inhibitor 3 是一种有效的选择性 受体相互作用蛋白2 激酶抑制剂,IC50 为 1 nM。 | |||
T11226 |
ERK1/2 inhibitor 1
|
ERK | MAPK |
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively. | |||
T36527 |
IL-4-inhibitor-1
|
IL Receptor | Immunology/Inflammation |
IL-4-inhibitor-1 是 IL-4 的抑制剂 (EC50 = 1.81 µM)。 | |||
T10409 |
ATX inhibitor 5
|
PDE | Metabolism |
ATX inhibitor 5 是一种有效且具有口服活性的 autotaxin (ATX) 抑制剂(IC50 : 15.3 nM),可降低 CCl4 诱导的肝纤维化水平,具有抗肝纤维化作用,。 | |||
T11199 |
Endothelial lipase inhibitor-1
|
Lipase | Metabolism |
Endothelial lipase inhibitor-1是有效,选择性的内皮脂肪酶抑制剂,IC50为 49 nM。 | |||
T118066 |
CDK9 inhibitor HH1
8019-9719 |
CDK | Cell Cycle/Checkpoint |
CDK9 inhibitor HH1 (8019-9719) 是人类 CDK2-cyclin A2复合物的抑制剂,IC50为2 μM。 | |||
T22135 |
PPIase-Parvulin Inhibitor
|
Others | Others |
PPIase-Parvulin Inhibitor 是一种抑制剂,可以抑制PPlase Pin1 和Pin4的细胞渗透。 | |||
T11850 |
LIN28 inhibitor LI71
|
||
LIN28 inhibitor LI71 是一种有效的细胞渗透性 LIN28 抑制剂,可消除 LIN28 介导的寡尿苷酸化,IC50 为 7 uM。它能直接绑定 CSD,抑制 LIN28 对 let-7 的作用活性。 | |||
T67833 |
HIV-1 inhibitor-54
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
HIV-1 inhibitor-54 是一种有效的 HIV-1 抑制剂,在 MT-4 细胞中对 WT HIV-1 (菌株 IIIB) x 显示出抗 HIV 活性(EC50 : 32 nM)。HIV-1 inhibitor-54 可用于研究病毒感染。 | |||
T9812 |
Tubulin inhibitor 24
|
Microtubule Associated | Cytoskeletal Signaling |
Tubulin inhibitor 24 是一种 tubulin 抑制剂,可以抑制微管蛋白聚合,以浓度依赖性方式诱导细胞周期停滞在 G2/M 期, 具有抗肿瘤活性且无明显毒性。 | |||
T79861 |
EGFR/ErbB-2 inhibitor-1
|
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
EGFR/ErbB-2 inhibitor-1 是一种选择性的 ErbB2/HER2 抑制剂,能有效地阻断ErbB2和HER2的信号传导。 | |||
T78701 |
Tubulin inhibitor 32
|
Apoptosis | Apoptosis |
Tubulin inhibitor 32是一种口服活性的新型微管抑制剂,具有抗增殖和抗肿瘤活性,可抑制微管聚合,可诱导细胞凋亡及在G2/M期引起细胞周期停滞。 | |||
T67704 |
mTOR inhibitor 9e
|
PI3K; mTOR | PI3K/Akt/mTOR signaling |
mTOR inhibitor 9e 是选择性的 mTOR 抑制剂,对 mTOR 和 PI3Kα的 IC50分别为0.68nM 和1359nM。 | |||
T69757 |
PDDC inhibitor
|
||
PDDC is the first nSMase2 inhibitor that possesses both favorable pharmacodynamics and pharmacokinetic (PK) parameters, including substantial oral bioavailability, brain penetration, and significant inhibition of exosome release from the brain in vivo. | |||
T10735 |
CDK4/6/1 Inhibitor
Crozbaciclib |
CDK | Cell Cycle/Checkpoint |
CDK4/6/1 Inhibitor (Crozbaciclib) 是一种 CDK4/6 抑制剂 (IC50s: 3 and 1 nM). CDK4/6抑制剂是一类用于治疗一些类型的激素受体阳性、her2阴性乳腺癌的化合物,可阻断了乳腺癌细胞分裂和繁殖的过程。 | |||
T60472 |
GSK-3β inhibitor 12
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 12 是一种选择性 GSK-3β 的抑制剂。GSK-3β inhibitor 12 抑制 49.11% 25 μM 的 GSK-3β 的活性和37.11% 50 μM 的 GSK-3β 的活性。GSK-3β inhibitor 12 可用于研究有脂多糖诱导的帕金森。 | |||
T72022 |
11β-HSD1 inibitor 19
|
||
11β-HSD1 inibitor 19 对 hHSD1 和 mHSD1 显示抑制活性,IC50 为 16 nM 和 10 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1579 |
Dihydrocucurbitacin B
二氢葫芦素 B,23,24-dihydrocucurbitacin B |
IL Receptor; TNF; COX | Apoptosis; Immunology/Inflammation; Neuroscience |
Dihydrocucurbitacin B (23,24-dihydrocucurbitacin B) 是从 Cayaponia tayuya 的根中分离得到的,具有抗癌活性。 | |||
T5268 |
D-Arabitol
D-Lyxitol,D-阿拉伯糖醇 |
Others; Endogenous Metabolite | Metabolism; Others |
D-Arabitol (D-Lyxitol) 是一种在人体内的累积能够能会导致神经毒性的多元醇。 | |||
T21066 |
Norepinephrine bitartrate salt
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Norepinephrine bitartrate salt 是一种肾上腺素能神经递质。 | |||
T6640 |
Ribitol
核糖醇,Adonite,阿东糖醇,Adonitol |
Others; Endogenous Metabolite | Metabolism; Others |
Ribitol (Adonite) 是一种戊糖醇,能够通过核糖还原形成。在酿酒酵母中增强 D-葡萄糖转向戊糖磷酸途径,能够用于生产核糖醇和 D-核糖。 | |||
TN2341 |
Cucurbitacin Q1
葫芦素F-25-乙酸酯,葫芦素Q1 |
Others | Others |
Cucurbitacin Q1 是一种天然的四环三萜,来源于Cucumis prophetarum。 | |||
TQ0195 |
1,5-Anhydrosorbitol
|
Others; Endogenous Metabolite | Metabolism; Others |
1,5-Anhydrosorbitol 是评价短期血糖控制情况的可靠指标,主要来源于食物。 | |||
T6805 |
Choline bitartrate
2,3,4-trihydroxy-4-oxobutanoate,2-hydroxyethyl(trimethyl)azanium,酒石酸氢胆碱 |
Others; AChR | Neuroscience; Others |
Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) 是一种存在于食物中的营养胆碱,可影响肝脏疾病、动脉粥样硬化和神经系统疾病等疾病。它是神经递质乙酰胆碱的前体,作为甲基供体参与各种代谢过程和脂质代谢。 | |||
TN1013 |
Cucurbitacin D
|
IL Receptor; JNK; STAT | Immunology/Inflammation; JAK/STAT signaling; MAPK; Stem Cells |
Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells. | |||
T3S1471 |
Cucurbitacin IIA
葫芦素Iia,Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA |
Apoptosis; Survivin | Apoptosis |
Cucurbitacin IIA (Dihydrocucurbitacin Q1) 是从园果雪胆中分离得到的一种三萜烯,可诱导细胞凋亡和增强自噬,有助于葫芦素IIA 对炎症相关疾病的抗炎活性。它可降低癌细胞中生存素的表达,降低磷酸化组蛋白 H3 的水平,增加裂解的 PARP 的水平。 | |||
T20550 |
Thiobarbituric acid
NSC4733,NSC 4733,4,6-二羟基-2-巯基嘧啶,NSC-4733 |
Antibacterial | Microbiology/Virology |
Thiobarbituric acid (NSC-4733) 具有抗菌活性。 | |||
T5853 |
Rubitecan
RFS 2000,鲁比特康,9-Nitrocamptothecin |
Topoisomerase | DNA Damage/DNA Repair |
Rubitecan (9-Nitrocamptothecin) 是一种与喜树碱相关的半合成药物,具有有效的抗肿瘤和抗病毒特性。它是一种 DNA 拓扑异构酶 I 抑制剂,以浓度依赖性方式抑制 DNA 拓扑异构酶 I 并在无细胞试验中增加超螺旋 DNA 的比例。 | |||
T0332 |
D-Sorbitol
山梨醇,Glucitol,Sorbitol,D-Glucitol |
Others; Endogenous Metabolite | Metabolism; Others |
D-Sorbitol (Sorbitol) 是一种六碳糖醇,能够用作糖的替代品。D-Sorbitol 能够用作稳定的赋形剂和/或等渗剂,保湿剂,增稠剂,甜味剂和膳食补充剂。 | |||
T5S1467 |
Cucurbitacin E
|
CDK; Autophagy | Autophagy; Cell Cycle/Checkpoint |
Cucurbitacin E 是从黄瓜的攀缘茎中分离得到的一种天然产物。它显着抑制细胞周期蛋白B1/CDC2复合物的活性,具有预防神经变性,具有强效的抗增殖、抗肿瘤、抗炎和镇痛作用行动。 | |||
T4S1469 |
Cucurbitacin IIb
葫芦素IIB,雪胆素乙 |
Apoptosis; Others | Apoptosis; Others |
Cucurbitacin IIb 是一种雪胆中的活性成分。它阻碍 STAT3,JNK 和 Erk1/2 的磷酸化,提高 IκB 和 NF-κB (p65) 的磷酸化水平,抑制 NF-κB (p65) 的核转位,降低 IκBα 和 TNF-α 的 mRNA 水平。它能够诱导细胞凋亡,具有抗炎作用。 | |||
T3404 |
Cucurbitacin B
Cuc B,葫芦素B,DATISCACIN,葫芦素 B,Amarine |
Apoptosis; PTEN; Integrin; Endogenous Metabolite; HIF; STAT; Autophagy | Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells |
Cucurbitacin B (Cuc B) 是一具有抗癌活性的天然产物。 | |||
TQ0196 |
Cucurbitacin I
NSC-521777,JSI-124,Elatericin B,葫芦素 I |
JAK; STAT | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Cucurbitacin I (JSI-124) 是从曲莲中提取的一种天然产物,是 JAK2/STAT3选择性抑制剂,有抗肿瘤活性。 | |||
T1064 |
Norepinephrine bitartrate monohydrate
酒石酸去甲肾上腺素,Levophed,Noradrenaline bitartrate monohydrate,降肾上腺素 |
Endogenous Metabolite; Adrenergic Receptor; Autophagy | Autophagy; GPCR/G Protein; Metabolism; Neuroscience |
Norepinephrine bitartrate monohydrate (Levophed) 是一种β1-选择性的肾上腺素能受体激动剂,EC50为 5.37 μM。 | |||
T82207 |
Hexanorcucurbitacin D
|
||
Hexanorcucurbitacin D是一种从Trichosanthes cucumeroides根中分离出的葫芦素类化合物,常用于心血管疾病(CVD)的研究。 | |||
TN3725 |
Cucurbitadienol
|
||
Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloar | |||
TN6276 |
3β,7β-Dihydroxy-25-methoxycucurbita-5,23-dien-19-al
|
||
3β,7β-Dihydroxy-25-methoxycucurbita-5,23-dien-19-al 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6276,CAS号为 132587-67-8。 | |||
T82554 |
Dihydroisocucurbitacin B
|
||
Dihydroisocucurbitacin B为一种源自Wilbrandia ebracteata根部的活性化合物。 | |||
TN5974 | Cucurbitacin A 2-O-β-D-glucopyranoside | ||
Cucurbitacin A 2-O-β-D-glucopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5974,CAS号为 1135141-76-2。 | |||
TN6275 |
3,7,25-Trihydroxycucurbita-5,23-dien-19-al
3β,7β,25-Trihydroxycucurbita-5,23-dien-19-al |
||
3,7,25-Trihydroxycucurbita-5,23-dien-19-al 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6275,CAS号为 85372-65-2。 | |||
T4S1472 |
Cucurbitacin S
|
||
Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities. | |||
TN5995 |
Cucurbitacin IIa 2-O-glucoside
Hemslecin A 2-O-glucoside,雪胆甲素苷 |
||
Cucurbitacin IIa 2-O-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5995,CAS号为 77704-34-8。 | |||
TN1533 |
Cucurbitacin A
|
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase. | |||
TN2887 |
3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid
|
Phosphatase | Metabolism |
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. | |||
TN6320 |
(19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol
|
||
(19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6320,CAS号为 1616120-83-2。 | |||
TN6333 |
(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol
|
||
(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6333,CAS号为 2281872-79-3。 | |||
TN6332 |
(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol
|
||
(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6332,CAS号为 1474062-47-9。 | |||
T83578 |
(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol
|
||
(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol 是一种葫芦烷型三萜。该化合物在 MTT 法检测中对癌细胞系 MCF-7、HepG2、Du145、Colon205 以及 HL-60 均未表现出抑制效果。 | |||
TN3074 | 5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol | Others | Others |
5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3074,CAS号为 81910-39-6。 | |||
TN2574 | 10-O-Ethylcannabitriol | Others | Others |
10-O-Ethylcannabitriol is a natural product from Cannabis sativa L. | |||
TN6956 |
Cucurbitacin C
|
||
Cucurbitacin C is a natural product. | |||
T83570 |
(23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol
|
||
(23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol,一种葫芦烷三萜,可从苦瓜籽中提取。 | |||
TN6305 |
3β,7β,19-Trihydroxy-25-methoxycucurbita-5,23-diene 7-O-glucoside
|
||
3β,7β,19-Trihydroxy-25-methoxycucurbita-5,23-diene 7-O-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6305,CAS号为 81910-37-4。 | |||
T81690 | Neocucurbitacin A | STAT | JAK/STAT signaling; Stem Cells |
Neocucurbitacin A (compound 7)是一种从沉香果皮提取的STAT3抑制剂,常用于抗癌研究。 | |||
TN6313 | (19R)-5β,19-Epoxy-19-methoxycucurbita-6,23-diene-3β,25-diol | ||
(19R)-5β,19-Epoxy-19-methoxycucurbita-6,23-diene-3β,25-diol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6313,CAS号为 332950-28-4。 | |||
TN3073 |
5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol
|
Others | Others |
5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3073,CAS号为 85372-72-1。 | |||
TN2909 |
3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al
|
Others | Others |
3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2909,CAS号为 1446447-97-7。 | |||
T81194 |
Schibitubin I
|
||
Schibitubin I,一种从Schisandra bicolor var. tuberculata果实中分离得到的木质素,具有神经保护活性。 | |||
TN5988 |
16,25-Di-O-acetylcucurbitacin F
16,25-O-Diacetyl-cucurbitane F,Cucurbitacin F 16,25-diacetate |
||
16,25-Di-O-acetylcucurbitacin F 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5988,CAS号为 2062685-10-1。 | |||
TN5972 |
3-epi-Isocucurbitacin B
|
||
3-epi-Isocucurbitacin B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5972,CAS号为 89647-62-1。 | |||
TN5990 |
Cucurbitacin V
|
||
Cucurbitacin V 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5990,CAS号为 152340-37-9。 | |||
TN6274 | 3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-dien-19-al | ||
3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-dien-19-al 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6274,CAS号为 85372-69-6。 | |||
TN1776 |
Isocucurbitacin B
|
Others | Others |
Isocucurbitacin B 对 HeLa 和 HT-29 人类癌细胞具有显着的抑制活性,IC50 值范围为 0.93 至 9.73uM。 | |||
TN6345 |
(19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol
|
||
(19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6345,CAS号为 874287-87-3。 | |||
TN1534 |
Cucurbitacin B 2-O-beta-D-glucoside
|
Others | Others |
Cucurbitacin B 2-o-α²-D-glucoside has anticancer activity. | |||
TN5949 |
5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol
|
||
5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5949,CAS号为 85372-70-9。 | |||
TN5978 |
7β-Hydroxycucurbitacin B
|
||
7β-Hydroxycucurbitacin B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5978,CAS号为 1135141-79-5。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02632 |
SIRP alpha Protein, Mouse, Recombinant (His)
SHP-1,CD172a,SIRP,SHPS-1,SIRP α,Ptpns1,signal-regulatory pro... |
Mouse | HEK293 Cells |
SIRP alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is BAA20376.1. | |||
TMPY-06051 |
SIRP alpha Protein, Human, Recombinant (hFc)
signal-regulatory protein alpha,SIRP alpha,PTPNS1,P84,CD172A... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64 kDa and the accession number is P78324-1. | |||
TMPY-01573 |
SIRP alpha Protein, Human, Recombinant (G75A, His)
PTPNS1,signal-regulatory protein alpha,SIRP,MYD-1,CD172A,MFR... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1. | |||
TMPY-06052 |
SIRP alpha V2 Protein, Human, Recombinant (His)
SIRP α,P84,PTPNS1,signal-regulatory protein α,signal-regulat... |
Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPK-01356 |
SIRP alpha V4 Protein, Human, Recombinant (His & Avi)
BIT,SIRP α V4,MFR,SHPS1,SIRPA,SIRP α,P84,MYD1,MYD-1... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01358 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01364 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-01357 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,S... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal. | |||
TMPK-00626 |
SIRP alpha V8 Protein, Human, Recombinant (His & Avi)
SIRP alpha,P84,MYD1,MYD-1,SHPS1,BIT,SIRP α V8,PTPNS... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V8 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-00307 |
SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated
SHPS1,SIRP alpha,SHPS-1,SIRPA,MYD-1,BIT,CD172a,MYD1... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated is expressed in HEK293 mam... | |||
TMPK-00628 |
SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,SIRP alpha,MYD-1,SIRP α,SHPS-1,SIRPA,SHPS1,MFR,SIRP α V3... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-01363 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00627 |
SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,MFR,MYD1,SHPS-1,SIRP alpha,SIRP α,SIRPα,MYD-1,PTPNS1,SIR... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00625 |
SIRP alpha V3 Protein, Human, Recombinant (His & Avi)
P84,SIRP alpha,CD172a,MFR,MYD-1,PTPNS1,SIRPA,SHPS1,MYD1,SIRP... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01362 |
SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated
MYD1,SIRP α V4,PTPNS1,BIT,SHPS1,SIRP alpha,SHPS-1,S... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPY-06054 |
SIRP alpha V8 Protein, Human, Recombinant (His)
SIRP α,BIT,SIRP,PTPNS1,P84,SIRP α(SIRP αV8),CD172A,... |
Human | HEK293 Cells |
SIRP alpha V8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPY-02636 |
SIRP alpha Protein, Mouse, Recombinant (hFc)
CD172a,AI835480,SIRP,signal-regulatory protein α,signal-regu... |
Mouse | HEK293 Cells |
SIRP alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is BAA20376.1. | |||
TMPY-06284 |
SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated
SIRP,P84,signal-regulatory protein α,BIT,SHPS1,CD17... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 65.85 kDa and the accession number is P78324-1. | |||
TMPY-05126 |
SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated
SIRP α,SIRP alpha,MYD-1,BIT,MFR,SHPS1,CD172A,P84,SI... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.8 kDa and the accession number is P78324-1. | |||
TMPK-00611 |
SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His)
MYD-1,SHPS1,MFR,PTPNS1,CD172a,SIRPA,SIRP α V2/CD172a,SHPS-1,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His) is expressed in HEK293 mammalian cells with... | |||
TMPK-00609 |
SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,PTPNS1,SIRPαV2,SIRPalpha V2,CD172a,MYD1,MYD-1,SHPS-1, |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPY-05263 |
SIRP alpha Protein, Human, Recombinant (mFc)
signal-regulatory protein alpha,SIRP alpha,SHPS1,MYD-1,PTPNS... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.7 kDa and the accession number is P78324-1. | |||
TMPK-00610 |
SIRP alpha V2 Protein, Human, Recombinant (hFc)
PTPNS1,MYD-1,MFR,SHPS1,SIRPalpha2,SIRPα2,SIRPA,SIRP α V2/CD1... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.... | |||
TMPY-06053 |
SIRP alpha V2 Protein, Human, Recombinant (mFc)
MFR,CD172A,P84,PTPNS1,SIRP alpha,SIRP α(SIRP αV2),signal-reg... |
Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.5 kDa and the accession number is AAH38510.1. | |||
TMPY-06248 |
SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated
SIRP α(SIRP αV2),BIT,signal-regulatory protein alph... |
Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPY-06055 |
SIRP alpha V8 Protein, Human, Recombinant (mFc)
signal-regulatory protein α,signal-regulatory protein alpha,... |
Human | HEK293 Cells |
SIRP alpha V8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.6 kDa and the accession number is AAH38510.1. | |||
TMPJ-00305 |
SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)
Inhibitory Feceptor SHPS-1,MyD-1 Antig,Brain Ig-Lik... |
Cynomolgus | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ... | |||
TMPJ-00306 |
SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs... |
Human | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ... | |||
TMPY-03572 |
PTRH2 Protein, Human, Recombinant (His)
PTH 2,PTH2,peptidyl-tRNA hydrolase 2,CGI-147,CFAP37,BIT<... |
Human | E. coli |
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death. | |||
TMPY-04815 |
C1 inhibitor Protein, Rat, Recombinant (His)
serpin peptidase inhibitor, clade G (C1 inhibit... |
Rat | HEK293 Cells |
C1 inhibitor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.7 kDa and the accession number is A6HMR4. | |||
TMPJ-00779 |
TNF alpha Protein, Rabbit, Recombinant
TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿瘤坏死因子,Tum... |
Rabbit | E. coli |
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ... | |||
TMPH-03201 |
CD40 Ligand Protein, Rabbit, Recombinant (His)
TNLG8B,CD40 ligand,CD40-L,CD40LG,Tumor necrosis factor ligan... |
Rabbit | P. pastoris (Yeast) |
N/A. CD40 Ligand Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.2 kDa and the accession number is G1SKP7. | |||
TMPY-02697 |
IgG Protein, Rabbit, Recombinant (T185A, N284S)
IgG |
Rabbit | HEK293 Cells |
IgG Protein, Rabbit, Recombinant (T185A, N284S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25 kDa and the accession number is P01870. | |||
TMPH-03203 |
FGFb Protein, Rabbit, Recombinant (His & SUMO)
|
Rabbit | E. coli |
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. FGFb Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli exp... | |||
TMPH-03208 |
IL-6 Protein, Rabbit, Recombinant (His)
|
Rabbit | P. pastoris (Yeast) |
IL-6 Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is Q9MZR1. | |||
TMPH-03209 |
CLNS1A Protein, Rabbit, Recombinant (His & Myc)
I(Cln),Chloride conductance regulatory protein ICln,Methylos... |
Rabbit | E. coli |
CLNS1A Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is Q28678. | |||
TMPH-03217 |
VEGFA Protein, Rabbit, Recombinant (His)
|
Rabbit | P. pastoris (Yeast) |
VEGFA Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 51.7 kDa and the accession number is XP_002714743.1. | |||
TMPH-03205 |
HINT1 Protein, Rabbit, Recombinant (His & Myc)
|
Rabbit | HEK293 Cells |
HINT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.6 kDa and the accession number is P80912. | |||
TMPH-00760 |
Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His)
Cutin hydrolase,CUTA,Cutinase |
Neocosmosporum cucurbitae | P. pastoris (Yeast) |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection. Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 23.7 kDa and the accession number is Q99174. | |||
TMPH-03207 |
IL-2 Protein, Rabbit, Recombinant (His)
|
Rabbit | E. coli |
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. IL-2 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.1 kDa and the accession number is O77620. | |||
TMPY-04663 |
TrkA Protein, Rabbit, Recombinant (His)
neurotrophic tyrosine kinase, receptor, type 1 |
Rabbit | HEK293 Cells |
TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa and the accession number is XP_008262512.1. | |||
TMPH-00761 |
Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant
Cutin hydrolase,CUTA,Cutinase |
Neocosmosporum cucurbitae | E. coli |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection. Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.4 kDa and the accession number is Q99174. | |||
TMPH-02841 |
Prohibitin Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with... | |||
TMPH-03198 |
MGAT1 Protein, Rabbit, Recombinant (His & Myc)
|
Rabbit | E. coli |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. MGAT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.2 kDa and the accession number is P27115. | |||
TMPY-04609 |
IL-17 Protein, Rabbit, Recombinant (His)
白细胞介素,白介素,interleukin 17A |
Rabbit | Baculovirus Insect Cells |
IL-17 Protein, Rabbit, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is G1SLF2. | |||
TMPH-02787 |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His) is expressed in Yeast. | |||
TMPH-03210 |
TFPI Protein, Rabbit, Recombinant (E. coli, His)
|
Rabbit | E. coli |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.8 kDa and the accession number is P19761. | |||
TMPJ-00958 |
B7-1 Protein, Rabbit, Recombinant (His)
Activation B7-1 antigen,T-lymphocyte activation antigen CD80... |
Rabbit | HEK293 Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ... | |||
TMPY-04831 |
NGFR/p75NTR Protein, Rabbit, Recombinant (hFc)
NGFR,nerve growth factor receptor (TNFR superfamily, member ... |
Rabbit | HEK293 Cells |
NGFR/p75NTR Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is XP_008269543.1. | |||
TMPH-00453 |
L-ascorbate oxidase Protein, Cucurbita maxima, Recombinant (His & SUMO)
|
Cucurbita maxima | E. coli |
L-ascorbate oxidase Protein, Cucurbita maxima, Recombinant (His & SUMO) is expressed in E. coli. | |||
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