368
116
12
4
53
Cat. No. | Product Name | ||
---|---|---|---|
L6750 | 活血化瘀中药单体库 | 580 compounds | |
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。 | |||
L4510 | 抗寄生虫库 | 419 compounds | |
419 种具有抗寄生虫活性的小分子化合物; | |||
L6740 | 抗结直肠癌中药单体化合物库 | 382 compounds | |
382 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具; | |||
L6730 | 抗病毒中药单体化合物库 | 268 compounds | |
268 种具有抗病毒活性的中药单体集合,是药物开发、药理研究的有效工具; | |||
L6600 | 胃肠炎天然产物库 | 219 compounds | |
219 种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6620 | 抗寄生虫天然产物库 | 253 compounds | |
253 个抗寄生虫相关的天然产物集合,是药物开发、药理研究的有效工具; | |||
L9001 | 食品添加剂化合物库 | 425 compounds | |
425种食品添加剂的集合 | |||
L6810 | 中药单体化合物库 | 2755 compounds | |
2755 种中药来源的单体化合物,是药物开发、药理研究等领域的有力工具; | |||
L6710 | 中药抗炎分子库 | 1246 compounds | |
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具; | |||
L8600 | 泛素化化合物库 | 210 compounds | |
210 种泛素化相关的小分子,用于高通量和高内涵筛选; | |||
L6220 | 蒙药化合物库 | 950 compounds | |
950 种蒙药来源的天然产物分子集合,可以用于高通量和高内涵筛选; | |||
L6720 | 抗COVID-19中药单体库 | 1147 compounds | |
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1147 种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0067 |
Mouse CD4+ Cell Isolation Kit (positive selection)
小鼠 CD4+ 细胞分选试剂盒 (阳选) |
||
C0066 |
Human CD34+ Cell Enrichment Kit (positive selection)
人 CD34+ 细胞富集试剂盒 (阴选) |
||
CL0050 |
Antiparasitic compound kit
Antiparasitic compound kit |
||
C0068 |
Mouse CD8+ Cell Isolation Kit (positive selection)
小鼠 CD8+ 细胞分选试剂盒 (阳选) |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11689 |
ITI-214
ITI214 |
PDE | Metabolism |
ITI-214 是一种中枢神经系统活性抑制剂,具有口服生物活性的PDE1抑制剂 (Kiof 58 pM),对其他 PDE 家族成员和一系列酶、受体、转运体和离子通道具有良好的选择性,在各种运动和认知功能的动物模型中显示出有效性。 | |||
T21069 |
Lumateperone
ITI 722,ITI722,ITI-007,卢美哌隆,ITI007 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Lumateperone (ITI 722) 是一种 5HT2A 受体拮抗剂和多巴胺受体磷蛋白调节剂 (DPPM)。 | |||
TQ0084 |
lumateperone Tosylate
ITI-007,Lumateperone甲苯磺酸盐 |
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
lumateperone Tosylate (ITI-007) 是5-HT 2A 受体拮抗剂,Ki 为 0.54 nM,突触前 D2受体的部分激动剂和突触后 D2受体的拮抗剂,Ki 为 32 nM。 | |||
T11688 |
ITI-214 free base
ITI214 free base |
Others | Others |
ITI-214 free base is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). | |||
T13237L |
Ropsacitinib
Tyk2-IN-8,PF-06826647 |
Tyrosine Kinases | Tyrosine Kinase/Adaptors |
Ropsacitinib (PF-06826647) 是一种选择性TYK2抑制剂。Ropsacitinib 与Tyk2催化活性JH1结构域结合(IC50:17nM)。 | |||
T16369 |
O-Desmethyl gefitinib
|
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
O-Desmethyl gefitinib 是依赖于 CYP2D6 活性形成的,是 Gefitinib 在人血浆中的活性代谢产物。在亚细胞试验中,它抑制 EGFR,IC50为 36 nM。 | |||
TP2100 |
Avexitide
Exendin-3 (9-39) amide,Exendin (9-39),艾塞那肽 |
Glucagon Receptor | GPCR/G Protein |
Avexitide (Exendin-3 (9-39) amide) 是一种特异竞争性的glucagon-like peptide-1 (GLP-1)受体拮抗剂。 | |||
T2609 |
Masitinib
AB1010,马赛替尼 |
Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck | Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit,IC50=200 nM),它还抑制PDGFRα/β(IC50s=540/800 nM),Lyn(对 LynB 的IC50=510 nM),Lck,较小程度上抑制FGFR3和FAK。它有抗增殖,促凋亡活性,且毒性低。 | |||
T6289 |
Dovitinib
TKI258,多韦替尼,CHIR-258,度维替尼 |
VEGFR; FGFR; FLT; PDGFR; c-Kit | Angiogenesis; Tyrosine Kinase/Adaptors |
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。 | |||
T6124 |
Mubritinib
木利替尼,TAK-165 |
EGFR; FGFR; JAK; PDGFR | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Mubritinib (TAK-165) 是选择性的EGFR2/HER2抑制剂,IC50值为6 nM。 | |||
T10431 |
Golidocitinib
AZD4205 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Golidocitinib (AZD4205) 是一种选择性 JAK1抑制剂,IC50值为 73 nM。 | |||
T67152 |
Dacomitinib Intermediate 2
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine |
Others | Others |
Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) 具有抗癌活性,可用于研究肺癌。 | |||
TP1412 |
RNAIII-inhibiting peptide TFA
RNAIII-inhibiting peptide(TFA),L-酪氨酰-L-丝氨酰-L-脯氨酰-L-色氨酰-L-苏氨酰-L-天冬氨酰胺酰-L-苯丙氨酸 |
Antibacterial | Microbiology/Virology |
RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) 抑制肽(TFA)抑制金黄色葡萄球菌,对蜂窝织炎、角膜炎、化脓性关节炎、骨髓炎和乳腺炎等疾病有效。 | |||
T4168 |
Visomitin
SKQ1 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Visomitin (SKQ1) 是一种靶向线粒体的抗氧化剂,表现出高效的线粒体穿透能力和有效的抗氧化能力。 | |||
T6156 |
Ruxolitinib (S enantiomer)
S-Ruxolitinib,环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯,Ruxolitinib S enantiomer,INCB018424,INCB18424 |
Tyrosine Kinases; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Ruxolitinib S enantiomer (INCB18424) 是 Ruxolitinib 的 S 型对映体,是一种JAK 抑制剂。 | |||
T1791L |
Ceritinib dihydrochloride
LDK378 dihydrochloride,双盐酸盐色瑞替尼 |
IGF-1R; ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
Ceritinib dihydrochloride (LDK378 dihydrochloride) 是一种选择性的、口服具有活性的、ATP 竞争性的ALK 酪氨酸激酶抑制剂 (IC50:200 pM)。它还抑制IGF-1R (IC50:8 nM),InsR (IC50:7 nM) 和 STK22D (IC50:23 nM)。它显示出良好的抗肿瘤作用。 | |||
T6321 |
Tofacitinib
托法替尼,Tasocitinib,CP-690550 |
ROCK; Apoptosis; JAK; Src | Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Tofacitinib (Tasocitinib) 是口服小分子 Janus 激酶抑制剂,用于治疗中度至重度类风湿性关节炎。 | |||
T1684 |
Nitisinone
尼替西农,NTBC,SC0735,Nitisone |
Others; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; Others |
Nitisinone (SC0735) 是一种 4-羟基苯丙酮酸双加氧酶抑制剂。 | |||
T22484 |
(±)-Propionylcarnitine chloride
Propionyl-DL-carnitine chloride |
Endogenous Metabolite | Metabolism |
(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) 是一种短链酰基肉碱的混合物,可用作膳食补充剂,可用于研究慢性糖尿病。 | |||
T37299 |
L-Palmitoylcarnitine chloride
|
||
Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 μM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the ant... | |||
T2483 |
Dacomitinib
达克替尼,PF-299804,PF-00299804,PF299 |
Apoptosis; EGFR | Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Dacomitinib (PF299) 是一种不可逆的特异性ERBB 家族抑制剂,作用于EGFR、ERBB2和ERBB4的IC50分别为 6 nM、45.7 nM 和 73.7 nM。 | |||
T2012 |
Oclacitinib
PF-03394197 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Oclacitinib (PF-03394197) 是一种有效的选择性 JAKs 抑制剂,IC50 为 10-99 nM;不抑制一组 38 种非 JAK 激酶 (IC50 > 1000 nM)。 | |||
T60128 |
N,N-Didesethyl Sunitinib Hydrochloride
|
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
N,N-Didesethyl Sunitinib Hydrochloride 是一种有效的AMPK 抑制剂,对AMPKα1和AMPK2的IC50分别为393nM 和141nM。 | |||
T35914 |
Epitinib succinate
HMPL-813 succinate |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Epitinib succinate (HMPL-813 succinate) 是一种具有口服活性和脑渗透性的 EGFR 酪氨酸激酶抑制剂,可用于癌症研究。 | |||
T14346 |
Aumitin
|
Others; Autophagy | Autophagy; Others |
Aumitin 是一种基于二氨基嘧啶的自噬抑制剂,以剂量依赖性抑制饥饿和雷帕霉素诱导的自噬,IC50分别为 0.12 μM 和 0.24 μM。它通过靶向复合物 I 抑制线粒体呼吸。 | |||
T5109 |
Avapritinib
BLU-285 |
PDGFR; c-Kit | Angiogenesis; Tyrosine Kinase/Adaptors |
Avapritinib (BLU-285) 是选择性的、高效的、具有口服活性的 KIT 和 PDGFRA 激活环突变激酶抑制剂,能够作用于 KIT D816V (IC50:0.27 nM) 和 PDGFRA D842V (IC50:0.24 nM)。它减弱 ABCB1 和 ABCG2 的传输功能。它与激酶的活性构象结合,并显示抗肿瘤活性。 | |||
T18885 |
3,6-Dichlorotrimellitic acid
|
Others | Others |
3,6-Dichlorotrimellitic acid 是一种制备多种二氯化荧光素和罗丹明 (如 TET 和 HEX) 的关键性前体试剂,这些氯化荧光素和罗丹明普遍用作寡核苷酸及 DNA 测序的标记。 | |||
T67847 |
Imatinib impurities3
|
Bcr-Abl; PDGFR; c-Kit | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Imatinib impurities3是一种蛋白激酶抑制剂,对 ABL1 wt、KIT wt 和 PDGFRR wt 的 IC50值分别为6.95μM 、0.245μM 和0.139μM 。 | |||
T7104 |
Dovitinib lactate
CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate |
VEGFR; FGFR; FLT; PDGFR; c-Kit | Angiogenesis; Tyrosine Kinase/Adaptors |
Dovitinib lactate (TKI-258 lactate) 是一种多靶点的酪氨酸激酶抑制剂,抑制FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和PDGFRα/β的IC50值分别为 1,2,8/9,10/13/8,27/210 nM。 | |||
T12427 |
Brepocitinib P-Tosylate
PF-06700841 P-Tosylate |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) 是一种有效的 JAK1和TYK2双重抑制剂,IC50值分别为 17 和 23 nM。它还抑制JAK2和JAK3,IC50值分别为 77 和 6.49 μM。 | |||
T2398 |
Tofacitinib Citrate
CP-690550 citrate,柠檬酸托法替尼,枸橼酸托法替尼,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate |
Apoptosis; Influenza Virus; JAK; Antibacterial; Antifungal | Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Microbiology/Virology; Stem Cells |
Tofacitinib Citrate (CP-690550 citrate) 是 JAK1/2/3抑制剂,IC50分别为112,20 和 1 nM。它具有抗菌,抗真菌和抗病毒活性。 | |||
T2485 |
Baricitinib
INCB028050,LY3009104,巴瑞克替尼 |
Tyrosine Kinases; JAK; Chk | Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Baricitinib (INCB028050) 是一种选择性,可口服的JAK1和JAK2抑制剂,IC50分别为5.9 nM 和 5.7 nM,具有潜在的抗炎、免疫调节和抗肿瘤活性。 | |||
T5965 |
Ditiocarb sodium
Sodium diethyldithiocarbamate,二乙基二硫代氨基甲酸钠 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Ditiocarb sodium (Sodium diethyldithiocarbamate) 是一种铜胶结率的促进剂。它可降低HIV 感染。 | |||
T12017 |
Methyllycaconitine citrate
MLA |
AChR | Neuroscience |
Methyllycaconitine citrate (MLA) 是一种可穿过血脑屏障的 α7 神经元烟碱乙酰胆碱受体(α7nAChR)拮抗剂,可用于研究神经系统疾病。 | |||
T14185 |
Alkynyl Palmitic Acid
|
Others; PROTAC Linker | Others; PROTAC |
Alkynyl Palmitic Acid 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T37992 |
15-Methyl Palmitic Acid
15-Methylpalmitic acid,15-Methylhexadecanoic acid |
||
15-methyl Palmitic Acid 是一种一种甲基化脂肪酸,广泛存在于动物脂质中,可能于调节脂肪代谢有关。 | |||
T62053 |
Lorpucitinib
JNJ-64251330 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Lorpucitinib (JNJ-64251330) 是一种可口服且具有选择性和有效性的 JAK 激酶抑制剂,用于研究与Janus 激酶 (JAK) 信号转导有关的炎症性疾病和胃肠道疾病。 | |||
T38253 |
Lauroyl-L-carnitine (chloride)
Lauroyl-L-carnitine Hydrochloride |
||
Lauroyl-L-carnitine (chloride) (Lauroyl-L-carnitine Hydrochloride)是一种酰基肉碱和表面活性剂,已被用于渗透猪肠细胞,以输送极性荧光探针荧光黄。 | |||
T6479 |
Dovitinib lactate hydrate
Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258 |
VEGFR; FGFR; FLT; PDGFR; c-Kit | Angiogenesis; Tyrosine Kinase/Adaptors |
Dovitinib lactate hydrate (TKI258) 是一种多靶点的酪氨酸激酶抑制剂,抑制 FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和 PDGFRα/β的 IC50值分别为 1,2,8/9,10/13/8,27/210 nM。 | |||
T37735 |
Stearoyl-L-carnitine chloride
C18 Carnitine,Stearoylcarnitine chloride |
||
Stearoyl-L-carnitine chloride(Acylcarnitine C18:0) 是一种存在于小脑中的长链酰基肉碱,抑制 GlyT2 ,是研究脂代谢的重要组成部分。 | |||
T4235 |
Roblitinib
FGF-401 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Roblitinib (FGF-401) 是一种口服有效的,高选择性的FGFR4抑制剂(IC50:1.9 nM),具有抗癌作用。 | |||
TP1127L1 |
Nemifitide acetate(173240-15-8 free base)
INN 00835 acetate |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) 是一种合成的五肽抗抑郁药,具有快速起效的潜力。它是黑色素细胞抑制因子 (MIF) 的肽类似物。 | |||
T35898 |
Izencitinib
TD-1473,JNJ-8398 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Izencitinib (JNJ-8398) 是一种具有口服活性和肠道选择性的 JAK 抑制剂,具有潜在的抗炎活性,可用于研究溃疡性结肠炎和克罗恩病。 | |||
T0374L |
Sunitinib
苏尼替尼,舒尼替尼,SU 11248 |
Apoptosis; Mitophagy; VEGFR; FLT; IRE1; PDGFR; c-Kit; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors |
Sunitinib (SU 11248) 是一种多靶点受体酪氨酸激酶 (RTK) 抑制剂,可以抑制 VEGFR2 和 PDGFRβ (IC50=80/2 nM)。Sunitinib 具有抗肿瘤活性,可以用于治疗肾癌和胃肠道肿瘤。 | |||
T0865 |
Ranitidine Hydrochloride
AH19065,盐酸雷尼替丁 |
P450; Antibacterial; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Ranitidine Hydrochloride (AH19065) 是一种具有口服活性的组胺 H2 受体选择性拮抗剂,IC50为 3.3 μM。它还是一种CYP2C19和CYP2C9的弱抑制剂,可抑制胃液分泌。 | |||
T10585 |
Bozitinib
CBT-101,PLB-1001 |
c-Met/HGFR | Tyrosine Kinase/Adaptors |
Bozitinib (PLB-1001) 是一种可透过血脑屏障的、高效的、选择性的的、 ATP 竞争性的小分子 c-MET 激酶抑制剂,能够与酪氨酸激酶超家族的常规 ATP 结合口袋结合。 | |||
T5382 |
Ritlecitinib
PF-06651600 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Ritlecitinib (PF-06651600) 是一种口服有效的选择性JAK3抑制剂,IC50值为 33.1 nM。 | |||
T0316 |
Citiolone
西替沃酮,Thioxidrene,Citiolase |
Others | Others |
Citiolone (Thioxidrene) 是一种用于肝脏治疗的药物,是氨基酸半胱氨酸的衍生物。 | |||
T12145L |
N-Desethylsunitinib hydrochloride
|
VEGFR; PDGFR; c-Kit | Angiogenesis; Tyrosine Kinase/Adaptors |
N-Desethylsunitinib hydrochloride 是舒尼替尼的主要且具有药理活性的代谢物,是有效的 ATP 竞争性 VEGFR、PDGFRβ 和 KIT 抑制剂。 | |||
T20704L |
Levitide acetate
Levitide acetate(114281-19-5 Free base) |
Others | Others |
Levitide acetate 是一种来自青蛙皮肤的抗菌肽。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1917 |
Mauritianin
|
Topoisomerase | DNA Damage/DNA Repair |
Mauritianin 是一种从 Acalypha indica 的花和叶中分离出来的山柰酚苷,是一种拓扑异构酶 I 抑制剂。Mauritianin 具有细胞保护活性。 | |||
TN1984 |
Neoisoliquiritin
|
Others | Others |
Neoisoliquiritin 是一种提取自甘草中的活性物质。 | |||
T3S1916 |
Heteroclitin D
异型南五味子丁素,异南五味子丁素;异型南五味子丁素 |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Heteroclitin D 是异形南五味子中的一种木脂素,可抑制 L 型钙通道,具有抗脂质过氧化作用。 | |||
T5S1891 |
Flaconitine
乙酰乌头碱,3-Acetylaconitine,Acetylaconitine |
Others; NF-κB | NF-κB; Others |
Flaconitine (Acetylaconitine) 是一种 NF-κB 抑制剂,是一种生物碱。 | |||
T7047 |
Dipalmitin
二棕榈酸甘油酯,1,3-Dipalmitin |
Others | Others |
Dipalmitin (1,3-Dipalmitin) 对软棕榈中间部分晶体具有模板作用。 | |||
T0743 |
DL-Carnitine
Carnitina,Carnitine,卡尼丁 |
Others | Others |
DL-Carnitine (Carnitina) 是肝脏和横纹肌的成分。在治疗上它用于刺激胰腺和胃的分泌并治疗高脂蛋白血症。 | |||
T5S0331 |
Isoliquiritin
异甘草苷,Neoisoliquritin |
p53; Antifungal | Apoptosis; Microbiology/Virology |
Isoliquiritin (Neoisoliquritin) 是从甘草根中分离得到的,具有镇咳、抗抑郁作用和抗真菌活性。它还能抑制血管生成和导管形成。 | |||
T19391 |
L-Hexanoylcarnitine
|
Others | Others |
L-Hexanoylcarnitine is found to be associated with celiac disease, is an acylcarnitine. | |||
TN1975 |
Neosmitilbin
Neoastilbin,新落新妇苷 |
Others | Others |
Neosmitilbin (Neoastilbin) 分离于 Garcinia mangostana。它能够有效抑制晶状体醛糖还原酶的活性,可能具有抗氧化和抗炎作用。 | |||
TQ0119 |
Cirsimaritin
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Cirsimaritin 具有抗菌、抗炎、抗肿瘤、抗氧化特性和肾脏保护作用。 Cirsimaritin 与 GABAA 受体上的苯二氮卓位点结合较弱。 | |||
T2980 |
Chondroitin sulfate
Chonsurid,Chondroitin polysulfate,硫酸软骨素 |
MMP; Others; Endogenous Metabolite; NO Synthase | Immunology/Inflammation; Metabolism; Others; Proteases/Proteasome |
Chondroitin sulfate (Chonsurid) 是一种糖胺聚糖,被广泛用于骨关节炎的研究。它能够减少炎症介质和凋亡过程,并能够减少炎性细胞因子,iNOS 和MMPs 产生。 | |||
T19581 |
Tiglyl carnitine
|
Endogenous Metabolite | Metabolism |
Tiglyl carnitine 与肺癌和肉碱和甘氨酸对3-酮硫解酶缺乏症有关 。 | |||
T5765 |
ranaconitine
羟基高乌碱,7-羟基高乌甲素 |
Apoptosis; Others | Apoptosis; Others |
Ranaconitine 是从高乌头中分离得到的一种二萜生物碱,具有心脏毒性。 | |||
T8212 |
Dichotomitin
|
Others | Others |
Dichotomitin 是一种提取自Belamcanda chinensis 根茎中的异黄酮。 | |||
T19384 |
Isovalerylcarnitine
|
Apoptosis; Cysteine Protease | Apoptosis; Proteases/Proteasome |
Isovalerylcarnitine (3-methylbutyrylcarnitine) 是 L-亮氨酸分解代谢和异戊酸的积累产生的小分子化合物,也是一种具有选择性和有效性的钙蛋白酶 (calpain) 激活剂,可促使细胞凋亡,与异戊酸血症有关,可作为异戊酸血症的标志。 | |||
T0243 |
Vanitiolide
Vanitiolid,香草吗啉 |
Others | Others |
Vanitiolide (Vanitiolid) 是一种具有利胆作用的药物。 | |||
T2806 |
Lappaconitine
高乌甲素,(+)-Lappaconitine |
P2X Receptor; Sodium Channel | Membrane transporter/Ion channel; Neuroscience |
Lappaconitine ((+)-Lappaconitine) 是从高乌头中分离得到的一种天然产物,可用于缓解疼痛的研究。 | |||
T20643 |
Cefoxitin
Rephoxitin,Cefoxitinum |
Cell wall; Antibacterial; Antibiotic | Immunology/Inflammation; Microbiology/Virology |
Cefoxitin (Rephoxitin) 是一种广谱的、可口服的第二代头孢霉素类抗生素。Cefoxitin 干扰细菌细胞壁的合成。其活性谱包括革兰氏阴性和革兰氏阳性菌,通常用于腹腔感染、盆腔感染和某些类型的妇科感染等腹部,对厌氧菌具有高效性。 | |||
T19398 |
L-Octanoylcarnitine
|
Endogenous Metabolite | Metabolism |
L-Octanoylcarnitine 是存在于血浆中的活性辛酰肉碱,是一种乳腺癌的潜在生物标志物。 | |||
T0846 |
L-Carnitine
L(-)-Carnitine,Levocarnitine,左旋肉碱 |
Endogenous Metabolite; Fatty Acid Synthase | Metabolism |
L-Carnitine (L(-)-Carnitine) 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。 | |||
T3325 |
Liquiritigenin
4',7-Dihydroxyflavanone,甘草素 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Liquiritigenin (4',7-Dihydroxyflavanone) 是一种黄烷酮,从甘草中分离得到,是高度选择性的雌激素受体β 激动剂,用于活化 ERE tk-Luc 的 EC50值为36.5 nM。 | |||
T8137 |
(Z)-Aconitic acid
顺乌头酸,顺式乌头酸,Cls-Aconitic acid |
Others; Endogenous Metabolite | Metabolism; Others |
(Z)-Aconitic acid 是 Aconitic acid 的顺式异构体。它是三羧酸循环中柠檬酸盐异构化为异柠檬酸盐的中间产物。 | |||
T2820 |
Glycitin
黄豆黄苷,Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside |
Others; Influenza Virus; Antibacterial | Microbiology/Virology; Others |
Glycitin (Glycitein 7-O-β-glucoside) 是一种从豆类中分离出来的天然异黄酮,有抗菌,抗病毒和雌激素作用,还有促进骨髓基质细胞和成骨细胞的增殖和抑制骨转换的生物学功能。 | |||
T13350 |
Wushanicaritin
|
Others | Others |
Wushanicaritin 在 DPPH 自由基清除活性测试中显示出显著的抗氧化活性 ,其IC50值为35.3 μM,具有抗肿瘤作用和抗炎活性。 | |||
T22291 |
Chitin
Chitin (From shrimp and crab shells) |
Others | Others |
Chitin 是一种大型的结构多糖,存在于真菌的细胞壁、昆虫的外骨骼以及鱼类和无脊椎动物的某些坚硬结构中。 | |||
TL0002 |
Liquiritin apioside
|
Others | Others |
Liquiritin apioside 是一种从甘草中获得的黄酮,具有镇咳活性。 | |||
T4S1876 |
3-Deoxyaconitine
|
Sodium Channel | Membrane transporter/Ion channel |
3-Deoxyaconitine 是一种二萜类生物碱,对钠离子通道有激活作用。 | |||
T19564 |
Stearoylcarnitine
Stearoyl-L-carnitine |
Endogenous Metabolite | Metabolism |
Stearoylcarnitine (Stearoyl-L-carnitine) 是一种脂肪酯脂质分子,是一种人内源代谢产物,可作为早发型子痫前期和晚发性子痫前期的生物标志物。 | |||
T5S1889 |
Yunaconitine
Guayewuanine B,滇乌头碱 |
Others | Others |
Yunaconitine (Guayewuanine B) 是一种乌头类生物碱,具有剧毒。 | |||
T6S2140 |
β-Anhydroicaritin
Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素 |
MMP; Others; TNF; Interleukin | Apoptosis; Immunology/Inflammation; Others; Proteases/Proteasome |
β-Anhydroicaritin 是从乳香提取的一种天然产物,具有重要的生物学和药理学作用,如抗骨质疏松症,雌激素调节和抗肿瘤特性。它改善牙周组织的降解,抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。它抑制细胞内 Ca2+的升高,并显著降低 iNOS 蛋白的表达。 | |||
T2203 |
D-Carnitine hydrochloride
(S)-Carnitine Hydrochloride,L-Carnitine hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) 已被用于研究麦角硫因素转运蛋白 SLC22A4 和肉毒碱转运蛋白 SLC22A5,也被用于使棕榈酸进入线粒体。 | |||
T3717 |
Hinokitiol
4-Isopropyltropolone,桧木醇,β-thujaplicin,β-桧木醇 |
DNA Methyltransferase; Virus Protease; Estrogen/progestogen Receptor; Nrf2 | Chromatin/Epigenetic; Endocrinology/Hormones; Immunology/Inflammation; Microbiology/Virology |
Hinokitiol (4-Isopropyltropolone) 是从日本扁柏中分离到的一种挥发油成分,可抑制紫外线 B 诱导的角质形成细胞凋亡,可调节雌激素受体信号传导并抑制人乳腺癌细胞的增殖。它具有抗感染、抗氧化及抗肿瘤等活性。 | |||
T3860 |
Isoliquiritin apioside
|
MMP; p38 MAPK; NF-κB | MAPK; NF-κB; Proteases/Proteasome |
Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成,显著降低 PMA 诱导的MMP9活性增加,并抑制 PMA 诱导的MAPK 和NF-κB 活化。 | |||
T13280 |
Valerylcarnitine
VALERYL-L-CARNITINE |
Endogenous Metabolite | Metabolism |
Valerylcarnitine (VALERYL-L-CARNITINE) 是一种短链脂肪酸,可用于研究 2 型糖尿病。 | |||
T6560 |
Lappaconitine hydrobromide
氢溴酸高乌甲素,Lappaconite HBr,Allapinine |
Others | Others |
Lappaconitine hydrobromide (Allapinine) 是天然生物碱类化合物,具有抗心律失常作用。 | |||
T19340 |
Glutarylcarnitine
O-glutaroyl-L-carnitine |
Endogenous Metabolite | Metabolism |
Glutarylcarnitine (O-glutaroyl-L-carnitine) 是大多数串联质谱新生儿筛查计划中监测的丙二酸尿症和谷草酸尿症 I 型的诊断代谢物。 | |||
T5S0761 |
Nitidine chloride
|
Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite | Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors |
Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的,具有抗疟疾活性。它通过多个靶点通路,起抗癌作用,抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。 | |||
T6475 |
(±)-Carnitine chloride
Monocamin,DL-Carnitine HCl,Bicarnesine,混旋肉碱盐酸盐,DL-Carnitine chloride |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
(±)-Carnitine chloride (Monocamin) 有D 和L 两种异构体。其中 L-carnitine 在脂肪酸的 β-氧化中起重要作用,也具有抗氧化作用和抗炎活性。 | |||
T22293 |
Chondroitine sulfate
Chondroitine sulfate (From cattle) |
Others | Others |
Chondroitine sulfate 是软骨的重要结构成分,已被用作治疗关节不适的膳食补充剂。 | |||
T0136 |
Citicoline
CDP-Choline,Citicholine,尼古林,cytidine 5'-diphosphocholine,cytidine diphosphate-choline |
Apoptosis; Dopamine Receptor; Endogenous Metabolite | Apoptosis; GPCR/G Protein; Metabolism; Neuroscience |
Citicoline (CDP-Choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体,有神经保护作用。 | |||
T2563 |
Acetyl-L-carnitine hydrochloride
Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,乙酰-L-肉(毒)碱盐酸盐,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) 是一种由内源性左旋肉碱的乙酰化形式的盐酸盐组成的营养补充剂,具有潜在的神经保护、认知增强、抗抑郁和免疫调节活性。还可缓解化疗、糖尿病或其他疾病引起的周围神经病变。此外,乙酰左旋肉碱可能通过增加T淋巴细胞成熟来调节免疫反应,并可能下调促炎细胞因子对病毒(如SARS-CoV-2)的反应。它还可能破坏ACE2信号通路并抑制活性氧(ROS)的产生。 | |||
T0725 |
Isoliquiritigenin
异甘草素,ISL,Isoliquiritigen,GU17 |
Apoptosis; Influenza Virus; Reductase; Autophagy | Apoptosis; Autophagy; Endocrinology/Hormones; Metabolism; Microbiology/Virology |
Isoliquiritigenin (ISL) 是从光果甘草根中分离得到的一种黄酮类天然产物,具有抗肿瘤的活性。它抑制流感病毒复制,EC50为 24.7 μM,还能抑制 aldose reductase 的活性,IC50值为 320 nM。 | |||
T12295 |
Oleoylcarnitine
Oleoyl-L-carnitine |
Endogenous Metabolite | Metabolism |
Oleoylcarnitine (Oleoyl-L-carnitine) 抑制腺嘌呤核苷酸转位酶 (AdNT) 活性,ic50为14 μM。Oleoylcarnitine 是检测神经分裂的重要指标。 | |||
T6S0630 |
Hypaconitine
|
P450; TNF | Apoptosis; Metabolism |
Hypaconitine 是从乌头属种分离的一种高毒性成分,可研究风湿病。 | |||
TN3194 |
6''-O-xylosyl-glycitin
|
Others | Others |
6''-O-xylosyl-glycitin 是从 Pueraria thunbergiana Benth 的花中分离出来的。 | |||
T2899 |
Liquiritin
Liquiritigenin-4'-O-glucoside,Liquiritoside,甘草苷 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Liquiritin (Liquiritigenin-4'-O-glucoside) 是一种从甘草中分离出的类黄酮,是一种竞争性的 AKR1C1 抑制剂,对 AKR1C1,AKR1C2 和 AKR1C3 的 IC50分别为 0.62 μM,0.61 μM 和 3.72 μM,在体内有效抑制 AKR1C1 介导的孕酮代谢。它是一种抗氧化剂,具有神经保护、抗癌、抗炎的活性。 | |||
T15157 |
Dodecanoylcarnitine
Lauroylcarnitine |
Endogenous Metabolite | Metabolism |
Dodecanoylcarnitine((-)-Lauroylcarnitine) 和脂肪酸氧化紊乱有关,使用 Dodecanoylcarnitine 可使鲑鱼降钙素的通透性增加。 | |||
TN2554 |
1-Monopalmitin
Glyceryl palmitate |
Apoptosis | Apoptosis |
1-Monopalmitin (Glyceryl palmitate) 是一种从Mougeotia nummuloides 和 Spirulina major 提取出来的小分子化合物,具有潜在的抗肿瘤活性,抑制A549和SPC-A1细胞增殖,诱导G2/M阻滞和半胱天冬酶依赖性细胞凋亡。 | |||
TN7030 |
Heteroclitin G
|
Others | Others |
Heteroclitin G 被发现是 KIS 补血活性的潜在生物标志物,定量分析为进一步药理研究提供了研究基础。 | |||
T14840 |
Butyrylcarnitine
|
Endogenous Metabolite | Metabolism |
Butyrylcarnitine 是血浆中的代谢物,是疾病引起异常代谢的指标,可用于诊断心力衰竭和胰腺囊肿。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00198 |
ITIH3 Protein, Human, Recombinant (His)
inter-α-trypsin inhibitor heavy chain 3,ITI-HC3,H3P... |
Human | HEK293 Cells |
ITIH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.4 kDa and the accession number is Q06033-1. | |||
TMPY-03044 |
Bikunin/AMBP Protein, Human, Recombinant (aa 1-203, His)
α-1-microglobulin/bikunin precursor,ITI,EDC1,alpha-... |
Human | HEK293 Cells |
Bikunin/AMBP Protein, Human, Recombinant (aa 1-203, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.3 kDa and the accession number is P02760. | |||
TMPY-00397 |
ITIH3 Protein, Human, Recombinant (hFc)
H3P,SHAP,inter-α-trypsin inhibitor heavy chain 3,inter-alpha... |
Human | HEK293 Cells |
ITIH3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 97.7 kDa and the accession number is Q06033-1. | |||
TMPJ-00234 |
AMBP Protein, Human, Recombinant (His)
α-1-Microglobulin,Uronic-Acid-Rich Protein,Inter-α-Trypsin I... |
Human | HEK293 Cells |
Protein AMBP belongs to the calycin superfamily and Lipocalin family. AMBP can be cleaved into three chains: α-1-microglobulin, inter-α-trypsin inhibitor light chain and trypstatin. AMBP is expressed by the liver and secreted in plasma. α-1-microglobulin occurs in many physiological fluids including the plasma, urine, and cerebrospinal fluid. Inter-α-trypsin inhibitor is present in the plasma and urine. α-1-microglobulin occurs as a monomer and also in complexes with IgA and albumin, Inter-α-try... | |||
TMPY-00363 |
Bikunin/AMBP Protein, Human, Recombinant (aa 206-348, His)
EDC1,ITILC,UTI,α-1-microglobulin/bikunin precursor,... |
Human | P. pastoris (Yeast) |
Bikunin/AMBP Protein, Human, Recombinant (aa 206-348, His) is expressed in yeast with His tag. The predicted molecular weight is 17.4 kDa and the accession number is CAA38587.1. | |||
TMPY-00326 |
Bikunin/AMBP Protein, Human, Recombinant (mFc)
ITI,HCP,HI30,IATIL,A1M,ITIL,UTI,ITI |
Human | HEK293 Cells |
Bikunin/AMBP Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 47.2 kDa and the accession number is P02760. | |||
TMPY-05822 |
Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)
|
HBV-D | E. coli |
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of a capsid containing pregenomic RNA (pgRNA) and the viral polymerase (Pol). HBV capsid assembly is an attractive target for new antiviral therapies. | |||
TMPY-02711 |
Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant
FHC,FTHL6,FTH,PIG15,PLIF,ferritin, heavy polypeptid... |
Human | E. coli |
FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative dis... | |||
TMPH-01542 |
ITIH4 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. | |||
TMPH-00478 |
DIT33 Protein, Dirofilaria immitis, Recombinant (His & Myc)
Pepsin inhibitor Dit33,DIT33 |
Dirofilaria immitis | E. coli |
Aspartyl protease inhibitor. DIT33 Protein, Dirofilaria immitis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.0 kDa and the accession number is Q27384. | |||
TMPH-03719 |
YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)
|
Yersinia enterocolitica | E. coli |
Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages. | |||
TMPH-03646 |
Omega-gliadin Protein, Triticum monococcum, Recombinant (E. coli, GST)
|
Triticum monococcum | E. coli |
N/A. Omega-gliadin Protein, Triticum monococcum, Recombinant (E. coli, GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 30.3 kDa and the accession number is P02865. | |||
TMPH-02413 |
Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO)
|
LCMV | E. coli |
Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.4 kDa and the accession number is P09991. | |||
TMPH-00527 |
Fibritin Protein, Enterobacteria phage T4, Recombinant (His & SUMO)
|
Enterobacteria phage T4 | E. coli |
Chaperone involved in tail fiber assembly and retraction. Acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. During phage assembly, twelve fibritin molecules attach to the phage neck via gp13: six molecules forming the collar and six molecules forming the whiskers. | |||
TMPH-00051 |
Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His)
Chitin deacetylase,MrCDA,CDA |
Amylomyces rouxii | E. coli |
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P50325. | |||
TMPH-03588 |
ComC Protein, S. mitis, Recombinant (His & KSI)
comC,CSP,Competence-stimulating peptide |
Streptococcus mitis | E. coli |
Acts as a pheromone, induces cells to develop competence for genetic transformation. ComC Protein, S. mitis, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 17.3 kDa and the accession number is O33666. | |||
TMPH-03738 |
Endochitinase B Protein, Zea mays, Recombinant (His & Myc)
ChitB,CHIB,Endochitinase B,Seed chitinase ... |
Zea mays | E. coli |
Defense against chitin-containing fungal pathogens. | |||
TMPY-05166 |
Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His)
HCV-1a E2 |
HCV | HEK293 Cells |
Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.4 kDa and the accession number is AAC15723.1. | |||
TMPY-00323 |
Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)
NS3 |
HCV | E. coli |
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, t... | |||
TMPH-03718 |
YopB Protein, Yersinia enterocolitica, Recombinant (His)
|
Yersinia enterocolitica | E. coli |
Plays a role in virulence. | |||
TMPH-00814 |
Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His)
|
HEV-3 | P. pastoris (Yeast) |
Major viral capsid protein that encapsidates the viral genome. Binds to the 5' end of the genomic RNA. Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.3 kDa and the accession number is Q9YLQ9. | |||
TMPH-00811 |
Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)
|
HDV | P. pastoris (Yeast) |
Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA. RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome. Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc) is expressed in yeast with N-6xHi... | |||
TMPH-00275 |
ITIH2 Protein, Bovine, Recombinant (His & KSI)
|
Bovine | E. coli |
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. ITIH2 Protein, Bovine, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 21.3 kDa and the accession number is P56651. | |||
TMPH-00809 |
Hepatitis C Genome polyprotein (His)
|
HCV | E. coli |
Hepatitis C Genome polyprotein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 71.3 kDa and the accession number is S4UAW6. | |||
TMPJ-01371 |
Limitin Protein, Mouse, Recombinant (His)
Ifnz,Lmtn,IFN-z,IFN-ζ,BGIF,interferon ζ,IFN-zeta,Limiti<... |
Mouse | HEK293 Cells |
Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of ... | |||
TMPH-00135 |
Endochitinase Protein, Avena sativa, Recombinant (His)
|
Avena sativa | E. coli |
This protein functions as a defense against chitin-containing fungal pathogens. Endochitinase Protein, Avena sativa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.7 kDa and the accession number is P86181. | |||
TMPH-03708 |
Chitin-binding lectin Protein, Viscum album, Recombinant (His)
Chitin-binding lectin |
Viscum album | E. coli |
Chitin-binding lectin which is specific for N-acetylglucosamine oligomers. Chitin-binding lectin Protein, Viscum album, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 11.4 kDa and the accession number is P81859. | |||
TMPH-03715 |
Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO)
|
Yersinia enterocolitica | E. coli |
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. Could play an important role in pathogenesis. | |||
TMPH-00771 |
Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO)
|
Glycine max | E. coli |
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. | |||
TMPH-02205 |
Titin Protein, Human, Recombinant (His)
|
Human | E. coli |
Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to ch... | |||
TMPY-02582 |
Ferritin light chain Protein, Human, Recombinant (His)
NBIA3,LFTD,MGC71996,ferritin, light polypeptide |
Human | E. coli |
Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Storage of iron in the tissues occurs in the form of ferritin and hemosiderin. The latter originates from ferritin that has undergone intracellular digestion of its protein shell, leaving the iron core. Ferritin and hemosiderin are components of a continuum. Fer... | |||
TMPH-01543 |
ITIH5 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
May act as a tumor suppressor. ITIH5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.6 kDa and the accession number is Q86UX2. | |||
TMPH-02841 |
Prohibitin Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with... | |||
TMPY-02840 |
Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
UBE1,ubiquitin-like modifier activating enzyme 1,UB... |
Human | Baculovirus Insect Cells |
UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue w... | |||
TMPH-00810 |
Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc)
|
HDV | P. pastoris (Yeast) |
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding. Packages the HDV ribonucleoprotein in hepatitis B virus empty particles. Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg. May inhibit viral RNA replication. Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) is expressed i... | |||
TMPH-02787 |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His) is expressed in Yeast. | |||
TMPH-03717 |
YopE Protein, Yersinia enterocolitica, Recombinant (His)
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Yersinia enterocolitica | E. coli |
Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis. | |||
TMPH-02730 |
ITIH2 Protein, Mouse, Recombinant (His & Myc)
|
Mouse | E. coli |
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. ITIH2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 79.6 kDa and the accession number is Q61703. | |||
TMPY-04135 |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)
HCV-E1 |
HCV | HEK293 Cells |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is AAC15725.1. | |||
TMPH-01541 |
ITIH4 Protein, Human, Recombinant (His)
|
Human | P. pastoris (Yeast) |
Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. | |||
TMPH-00812 |
Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO)
|
HEV-1 | E. coli |
Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways. Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO) is... | |||
TMPY-00296 |
Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His)
HCV-1a E2 |
HCV | HEK293 Cells |
Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is BAA03581.1. | |||
TMPH-02364 |
Japanese encephalitis virus Genome polyprotein (His & SUMO)
|
JEV | E. coli |
Japanese encephalitis virus Genome polyprotein (His & SUMO) is expressed in E. coli. | |||
TMPY-00603 |
YM1/Chitinase 3 Like 3 Protein, Mouse, Recombinant (His)
Ym1 |
Mouse | HEK293 Cells |
YM1/Chitinase 3 Like 3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.8 kDa and the accession number is O35744. | |||
TMPH-03467 |
CspA Protein, Salmonella enteritidis, Recombinant (His & Myc)
CS7.4,CSP-A,cspA,Cold shock protein CspA,7.4 kDa cold shock ... |
Salmonella enteritidis | E. coli |
Binds to and stimulates the transcription of the CCAAT-containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'. CspA Protein, Salmonella enteritidis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.7 kDa and the accession number is P0A9Y5. | |||
TMPH-03647 |
Omega-gliadin Protein, Triticum monococcum, Recombinant (GST)
|
Triticum monococcum | P. pastoris (Yeast) |
N/A. Omega-gliadin Protein, Triticum monococcum, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 30.3 kDa and the accession number is P02865. | |||
TMPH-02788 |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His)
|
Mouse | E. coli |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-03097 |
Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc)
Beta-elicitin cryptogein,CRY |
Phytophthora cryptogea | E. coli |
Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families. Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins. Might interact with the lipidic molecules of the plasma membrane. Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.3 kDa and the accession... | |||
TMPH-03716 |
Invasin Protein, Yersinia enterocolitica, Recombinant (His & SUMO)
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Yersinia enterocolitica | E. coli |
Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins. | |||
TMPH-02412 |
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc)
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LCMV | E. coli |
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.9 kDa and the accession number is P07399. | |||
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