Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) 是一种由内源性左旋肉碱的乙酰化形式的盐酸盐组成的营养补充剂,具有潜在的神经保护、认知增强、抗抑郁和免疫调节活性。还可缓解化疗、糖尿病或其他疾病引起的周围神经病变。此外,乙酰左旋肉碱可能通过增加T淋巴细胞成熟来调节免疫反应,并可能下调促炎细胞因子对病毒(如SARS-CoV-2)的反应。它还可能破坏ACE2信号通路并抑制活性氧(ROS)的产生。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 mg | ¥ 118 | 现货 | ||
100 mg | ¥ 158 | 现货 | ||
200 mg | ¥ 218 | 现货 | ||
500 mg | ¥ 343 | 现货 | ||
1 g | ¥ 496 | 现货 | ||
5 g | ¥ 993 | 现货 | ||
10 g | ¥ 1,470 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 546 | 现货 |
产品描述 | Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neuroprotective, cognitive-enhancing, anti-depressive and immunomodulating activities. It may also relieve peripheral neuropathy induced by chemotherapy, diabetes or other diseases. In addition, acetyl-L-carnitine may modulate the immune response by increasing T-lymphocytes maturation and may downregulate pro-inflammatory cytokines in response to viruses, such as SARS-CoV-2. It may also disrupt the ACE2 signaling pathway and inhibit the production of reactive oxygen species (ROS). |
别名 | Acetyl L-carnitine hydrochloride, O-Acetylcarnitine, 乙酰-L-肉(毒)碱盐酸盐, O-acetyl-L-carnitine, O-Acetyl-L-carnitine hydrochloride |
分子量 | 239.7 |
分子式 | C9H18ClNO4 |
CAS No. | 5080-50-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (125.16 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 4.1719 mL | 20.8594 mL | 41.7188 mL | 104.297 mL |
5 mM | 0.8344 mL | 4.1719 mL | 8.3438 mL | 20.8594 mL | |
10 mM | 0.4172 mL | 2.0859 mL | 4.1719 mL | 10.4297 mL | |
20 mM | 0.2086 mL | 1.043 mL | 2.0859 mL | 5.2149 mL | |
50 mM | 0.0834 mL | 0.4172 mL | 0.8344 mL | 2.0859 mL | |
100 mM | 0.0417 mL | 0.2086 mL | 0.4172 mL | 1.043 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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