344
87
2
82
Cat. No. | Product Name | ||
---|---|---|---|
L5400 | 抗心血管疾病化合物库 | 1408 compounds | |
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4900 | 心血管毒性化合物库 | 131 compounds | |
131 种心血管毒性化合物的独特集合,可用于毒理学研究; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T31482 |
Diloxanide
Diloxanid,RD 3803,RD3803,RD-3803,Diloxanida,二氯尼特 |
Parasite | Microbiology/Virology |
Diloxanide (RD3803) 是一种抗原虫制剂,可研究组织学内阿米巴原虫或者其他原虫感染引起的无症状肠道阿米巴病。它是一种活性的鲁米那抗阿米巴试剂,是由其前药二氯尼特糠酸酯在胃肠道中水解得来的。 | |||
T21740 |
RD162
|
Androgen Receptor | Endocrinology/Hormones |
RD162 是一种与雄激素受体 (AR) 特异性结合的非甾体抗雄激素 (NSAA)。 | |||
T19546 |
Deprodone propionate
丙酸地泼罗酮,RD20000 |
Others | Others |
Deprodone propionate, a corticosteroid, is synthesized by esterification with propionic acid at the 17-position and deoxidation at the 21-position of the prednisolone skeleton. | |||
T12696 |
RD3-0028
|
Others | Others |
RD3-0028 is a potent and selective RSV replication inhibitor(EC50 of 4.5 μM). | |||
T6123 |
Verdinexor
KPT-335 |
CRM1 | Membrane transporter/Ion channel |
Verdinexor (KPT-335) 是一种特异性 XPO1/CRM1 抑制剂,具有口服生物利用度。 | |||
T17284 |
Zardaverine
BY 290,B 84290 |
PDE | Metabolism |
Zardaverine (BY 290) 是一种可口服且具有选择性和有效性的 PDE3/4 抑制剂 ,具有支气管扩张活性和抗肝癌活性。Zardaverine 在血小板中的作用是通过PDE III同工酶介导,可用于研究急性肾衰竭呵呵慢性气流阻塞。 | |||
T61318 |
BRD4 Inhibitor-20
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
BRD4 Inhibitor-20是一种有效的溴结构域蛋白4(BRD4)抑制剂,具有口服活性。BRD4 Inhibitor-20在癌细胞系中具有抗增殖活性,并被用于各种癌症的研究,如结肠癌。 | |||
T7791 |
Iberdomide
CC-220 |
Apoptosis; Ligand for E3 Ligase | Apoptosis; PROTAC |
Iberdomide (CC-220) 是一种口服有效的 cereblon E3 连接酶调节剂,对 cereblon 结合亲和力的 IC50约为150 nM。它是沙利度胺的衍生物,具有抗肿瘤和免疫刺激活性。 | |||
T9568 |
SGC-SMARCA-BRDVIII
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
SGC-SMARCA-BRDVIII 是SMARCA2/4和PB1(5)选择性抑制剂,其Kd 值分别为 35 nM,36 nM 和 13 nM。它还抑制PB1(2)和PB1(3),Kd 值分别为 3.7 和 2.0 μM。它可阻断 3T3-L1 鼠成纤维细胞的脂肪生成。 | |||
T30577 |
BRD0418
BRD 0418,BRD-0418 |
Others | Others |
BRD0418作为 TRIB1表达的上调因子,导致肝脏脂蛋白代谢从脂肪生成到清除的重新编程。 | |||
T28509 |
RDR03871
RDR 03871,ZINC20458540,RDR-03871 |
Mdm2 | Apoptosis |
RDR03871是一种 MDM2抑制剂。 | |||
T30798 |
Cerlapirdine
PF05212365,P -05212365,SAM-531,SAM531,PF-05212365,SAM 531,WAY-262,531 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Cerlapirdine (PF-05212365) 是一种选择性 5-羟色胺 6 (5-HT6) 受体的完全拮抗剂,用于治疗与阿尔茨海默病和精神分裂症相关的认知障碍。 | |||
T32191 |
Irdabisant
CEP-26401,CEP 26401,CEP26401 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Irdabisant (CEP-26401) 是选择性、口服活性和血脑屏障渗透性的组胺 H3 受体 (histamine H3 receptor, H3R) 拮抗剂/逆激动剂。Irdabisant 显示人 H3R 和大鼠 H3R 的 Ki 分别为 2.0 nM 和 7.2 nM。Irdabisant 抑制 hERG 电流的活性相对较低 (IC50= 13.8 μM)。在大鼠社会认知模型中,Irdabisant 具有认知增强和唤醒作用。Irdabisant 可用于研究精神分裂症或认知障碍。 | |||
T67886 |
Girard's Reagent T
Trimethylacetohydrazideammonium Chloride |
Others | Others |
Girard's Reagent T (Trimethylacetohydrazideammonium Chloride) 是生化试剂。Girard's Reagent T 在温和的酸性或碱性条件下,与含有α-二羰基官能团的醛类和酮类反应,生成强吸收紫外线的加成化合物 | |||
T77339 |
BRD4-IN-4
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
BRD4-IN-4 是一种具有选择性的 BRD4 抑制剂 ,对 BRD4 的IC50值为 6.83 μM。BRD4-IN-4 选择性抑制 MV4-11 细胞系增殖并将细胞阻滞在 G1 期。BRD4-IN-4可用于研究 MLL 白血病。 | |||
T78555 |
BRD4 Inhibitor-27
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
BRD4 Inhibitor-27 是一种有效的 BRD4 抑制剂,对 BRD4 BD1 和 BRD4 BD2 具有抑制作用, IC50 分别为 9.6 和 11.3 μM。BRD4 Inhibitor-27 具有抗癌活性,可用于研究乳腺癌。 | |||
T64117 |
BRD4-BD1-IN-2
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
BRD4-BD1-IN-2 是一种具有选择性和有效性的 BRD4-BD1 抑制剂,IC50 值为 2.51 µM ,是对 BRD4-BD2 抑制活性的 20 倍。BRD4-BD1-IN-2 可用于研究心血管疾病和癌症相关疾病。 | |||
T1229 |
Erdosteine
厄多司坦,RV 144,KW-9144 |
NF-κB; Antibacterial; Adenosine deaminase | Metabolism; Microbiology/Virology; NF-κB |
Erdosteine (RV 144) 抑制脂多糖诱导的NF-κB 激活,具有粘液调节、抗菌、抗炎、抗氧化和自由基清除作用。 | |||
T1774 |
Intepirdine
RVT-101,SB 742457,GSK-742457 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Intepirdine (GSK-742457) 是5-HT6受体拮抗剂,pKi 为9.63,用于研究阿尔茨海默病治疗的试验。 | |||
T6165 |
Bardoxolone Methyl
RTA 402,CDDO Methyl ester,TP-155,甲基巴多索隆,NSC 713200 |
Apoptosis; IκB/IKK; Ferroptosis; Nrf2; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; NF-κB |
Bardoxolone Methyl (TP-155) 是一种合成的三萜类化合物,作为 Nrf2通路的激活剂和 NF-κB 途径的抑制剂,具有潜在的抗肿瘤和抗炎活性。 | |||
T7212 |
Delavirdine mesylate
U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate) |
HIV Protease; Reverse Transcriptase | Microbiology/Virology; Proteases/Proteasome |
Delavirdine mesylate (BHAP-U 90152(mesylate)) 是一种口服活性非核苷逆转录酶抑制剂。它抑制 HIV-1 病毒复制,可以用于艾滋病的相关研究。它选择性地抑制 HIV-1 逆转录酶,其选择性超过 DNA 聚合酶 α 和 DNA 聚合酶 δ 。 | |||
T8233 |
BRD3308
|
Apoptosis; HIV Protease; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome |
BRD3308 是一种高选择性的HDAC3抑制剂,IC50为 54 nM。它可激活HIV-1转录并破坏HIV-1潜伏期。它抑制由炎性细胞因子或糖脂毒性应激诱导的胰腺 β 细胞凋亡,并增加功能性胰岛素释放。 | |||
T10603 |
BRD-6929
|
HIV Protease; HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome |
BRD-6929 是一种选择性的脑渗透性的HDAC1和HDAC2抑制剂 ,IC50值为 1 和 8 nM。它对 HDAC1 和 HDAC2 有高亲和力,Ki 值为 0.2 和 1.5 nM。它可研究情绪相关行为。 | |||
T9617 |
RdRP-IN-2
|
SARS-CoV | Microbiology/Virology |
RdRP-IN-2 是一种依赖于 RNA 的 RNA 聚合酶 (RdRp) 抑制剂。它显著抑制 SARS-CoV-2 RdRp,IC50 为 41.2 µM。它还抑制猫冠状病毒 (FIPV) 复制。 | |||
T24040 |
ERDRP-0519
ERDRP0519,ERDRP 0519 |
Antiviral | Immunology/Inflammation |
ERDRP-0519是一种口服可用的小分子抑制剂,针对麻疹病毒(MeV)聚合酶。它在松鼠猴(Saimiri sciureus)中有效预防麻疹病,并在纳摩尔范围内展现出对棘皮动物病毒的强大抑制作用。 | |||
T8005 |
Cardiogenol C hydrochloride
2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐,Cardiogenol C HCl,Cardiogenol C |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
Cardiogenol C hydrochloride (Cardiogenol C) 是一种细胞渗透性嘧啶诱导剂,能够促使 ESCs 分化为心肌细胞。在有限的可塑性范围内,它可以对已经沿袭的祖细胞类型产生心肌生成效应,是一种心肌生成试剂,在动物模型中可以用作细胞移植研究中提高心脏修复的工具。 | |||
T6189 |
Mirdametinib
PD325901,PD0325901 |
Apoptosis; MEK; Autophagy | Apoptosis; Autophagy; MAPK |
Mirdametinib (PD325901) 是一种 MEK 抑制剂 (IC50=0.33 nM),具有选择性、非 ATP 竞争性和口服活性。Mirdametinib 具有抗肿瘤活性,可以抑制 p-ERK1/2 的表达并诱导细胞凋亡。 | |||
T19900 |
ARDP0006
1,8-二羟基-4,5-二硝基蒽醌 |
Others | Others |
ARDP0006 是 NS2B-NS3 蛋白酶的抑制剂。 | |||
T62356 |
Mardepodect hydrochloride
PF-2545920 HCl,Mardepodect HCl,MP-10 HCl,PF-02545920 HCl |
Apoptosis; PDE | Apoptosis; Metabolism |
Mardepodect hydrochloride (Mardepodect HCl) 是一种可穿过血脑屏障且具有口服活性的、选择性和高效性的 PDE10A 抑制剂(IC50 :0.37 nM)。Mardepodect hydrochloride 可上调编码特定生长因子、转录因子、细胞信号分子和细胞表面蛋白的基因,同时下调广泛的可靶向细胞周期和细胞凋亡相关基因。 | |||
T26897 |
BRD2492
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
BRD2492 是一种具有选择性和有效的 HDAC1 和 HDAC2 双重抑制剂,具有潜在的抗癌、抗肿瘤和抗增殖活性,抑制 HDAC1/2 、HDAC3 和 HDAC6。BRD2492 对乳腺癌细胞系的生长有抑制作用,诱导细胞凋亡。 | |||
T10608 |
BRD5648
(R)-BRD0705 |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
BRD5648 ((R)-BRD0705) 是 BRD0705 的 阴性对照,BRD0705 是旁系选择性和口服有效的 GSK3α 抑制剂,Kd 为 4.8 μM,IC50为 66 nM。与 GSK3β (IC50为 515 nM) 相比,BRD0705 对 GSK3α 的选择性更高 (8 倍)。BRD0705 可用于急性髓细胞性白血病。 | |||
TP1289 |
Cardiotoxin Analog (CTX) IV (6-12) TFA
Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE) |
Others | Others |
Cardiotoxin Analog (CTX) IV (6-12) TFA(115722-23-1 free base) 是 Cardiotoxin Analog (CTX) IV 的部分肽。从台湾眼镜蛇毒液中分离出的心脏毒素类似物 IV。 CTX IV 是一种独特的蛇毒心脏毒素。 | |||
T6859 |
I-BRD9
GSK602 |
Epigenetic Reader Domain | Chromatin/Epigenetic |
I-BRD9 (GSK602) 是一种选择性的 BRD9 细胞抑制剂,pIC50 为 7.3。 | |||
T10602L |
BRD 4354
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
BRD 4354 是 HDAC5 和 HDAC9 的抑制剂,对 HDAC5 和 HDAC9 的 IC50 值分别为 0.85 和 1.88 μM。 | |||
T9329 |
BRD0639
|
Histone Methyltransferase | Chromatin/Epigenetic |
BRD0639 是首创的PRMT5-substrate adaptor interaction 的抑制剂。BRD0639 是一种 PRMT5 结合基序 (PBM) 竞争性抑制剂,可以支持 PBM 依赖的 PRMT5 活性的研究。 | |||
T6104 |
Cerdulatinib hydrochloride
Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride |
MLK; c-Fms; Tyrosine Kinases; Hippo pathway; JAK; Syk | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors |
Cerdulatinib hydrochloride (PRT2070 hydrochloride) 是一种选择性可逆,具有口服活性、 ATP 竞争性的 SYK 和 JAK 的双重抑制剂,抑制 JAK1、2、3、SYK 和 Tyk2的 IC50值分别为12、6、8、32 和 0.5 nM。它可用于研究自身免疫性疾病和B 细胞恶性肿瘤。 | |||
T33816 |
Ordopidine
ACR-325,ACR 325,ACR325 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Ordopidine (ACR325) 是一种多巴胺能稳定剂,可抑制精神刺激剂引起的多动症,并在不活动时刺激行为。Ordopidine 在体外作为多巴胺 D2 受体拮抗剂起作用,尽管亲和力低,但其依赖于特定状态的行为效应特征是 D2 受体拮抗剂所不具备的。 | |||
T25175 |
BRD 9757
BRD9757,N-Hydroxy-1-cyclopentene-1-carboxamide,BRD-9757 |
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) 是 HDAC6 的选择性抑制剂 (IC50 = 30 nM)。 | |||
T83979 |
Sulcardine 2HCl
Sulcardine 2HCl(343935-60-4 Free base),HBI-3000 2HCl |
HER; Sodium Channel | Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors |
Sulcardine 2HCl 是一种多离子通道阻滞剂,具有抗心律失常作用,可阻断 hERG 和hNav1.5通道的特性,可用于研究心房颤动和室性心律失常。 | |||
T6562 |
Latrepirdine dihydrochloride
Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin |
Beta Amyloid; 5-HT Receptor; Adrenergic Receptor; GluR; Autophagy; Histamine Receptor | Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) 是一种具有口服活性和神经活性的多种药物靶点的拮抗剂,可刺激淀粉样前体蛋白分解代谢和 β-淀粉样蛋白分泌。 | |||
T8405 |
Vardenafil hydrochloride
伐地那非,盐酸伐地那非 |
PDE | Metabolism |
Vardenafil hydrochloride 是口服具有活性的、高效的、选择性的磷酸二酯酶 5抑制剂。它对 PDE1 (180 nM),PDE6 (11 nM),PDE2,PDE3,PDE4 (>1000 nM) 具有选择性。它能够非竞争性地抑制环磷酸鸟苷水解,提高 cGMP 水平。它可用于勃起功能障碍的研究。 | |||
T3431 |
Pardoprunox hydrochloride
SLV-308 hydrochloride,DU-126891 hydrochloride,帕多芦诺盐酸盐 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Pardoprunox hydrochloride (SLV-308 hydrochloride) 是多巴胺受体 D2、D3部分激动剂和5-HT1A 激动剂,pEC50分别为 8、9.2 和 6.3。 | |||
T11948 |
Masupirdine free base
Masupirdine,SUVN-502 free base |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Masupirdine free base(SUVN-502 free base)是一种可口服且可穿过血脑屏障的 5-HT6 受体拮抗剂,对人类 5-HT6 受体的 Ki 值为 2.04 nM。Masupirdine free base 具有高效性和选择性且对多种靶点都具有抑制作用。Masupirdine free base 可用于研究像阿尔茨海默病类的神经系统疾病。 | |||
T12664 |
(Rac)-BRD0705
|
Others | Others |
(Rac)-BRD0705 是 BRD0705 的活性较低的外消旋体。 BRD0705 是一种有效的特异性 GSK3α 抑制剂。 | |||
T27795L |
(Iso)-Landipirdine
(Iso)-SYN120,(Iso)-RO5025181,(Iso)-Landipirdine(Iso-1000308-25-7) |
5-HT Receptor | GPCR/G Protein; Neuroscience |
(Iso)-Landipirdine((Iso)-RO5025181) 是一种具有选择性和有效性的 5-HT6R 拮抗剂。(Iso)-Landipirdine 对 hERG 药效团有明显影响,可用于研究阿尔茨海默病类的神经系统疾病。 | |||
T19736 |
Aniline mustard
Mesylerythrol,NSC-18429,N,N-双(2-氯乙基)苯胺,Lymphocin |
Others | Others |
Aniline mustard (Mesylerythrol) 是具有抗肿瘤活性的烷基化芥末。 | |||
T12896L |
Shepherdin 79-87 acetate
Shepherdin 79-87 acetate (861224-28-4 free base) |
HSP; Survivin | Apoptosis; Cytoskeletal Signaling; Metabolism |
Shepherdin 79-87 acetate 是 Hsp90 和 survivin 之间复合物的拟肽拮抗剂,survivin 是肿瘤细胞活力的另一个关键调节剂。 | |||
T9629 |
BRD4 Inhibitor-24
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
BRD4 Inhibitor-24 是一种具有抗肿瘤活性的 BRD4 小分子抑制剂。 | |||
T26778L |
Besipirdine hydrochloride
HP 749 hydrochloride,Besipirdine hydrochloride(119257-34-0 Free base) |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Besipirdine hydrochloride 是一种非受体依赖性拟胆碱化合物,具有α-肾上腺素能活性和心血管活性。Besipirdine hydrochloride 抑制电压依赖性钠钾通道,抑制生物胺的摄取。Besipirdine hydrochloride 可减少大鼠的时间表诱导的烦渴,增强中枢神经系统中的胆碱能和肾上腺素能神经传递。 | |||
T16499 |
Mardepodect
PF-2545920 |
PDE | Metabolism |
Mardepodect (PF-2545920) 是一种有效的、口服具有活性的、可透过血脑屏障的、选择性的 PDE10A 抑制剂,IC50=0.37 nM,比作用于其他 PDE 选择性高 1000 多倍。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2878 |
Ginsenoside Rd
Panaxoside Rd,Sanchinoside Rd,人参皂苷Rd,人参皂苷 Rd,Gypenoside VIII |
P450; Calcium Channel; NF-κB; COX; Endogenous Metabolite | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB |
Ginsenoside Rd (Gypenoside VIII) 抑制 TNFα 诱导的NF-κB 转录活性,还抑制COX-2和iNOSmRNA 的表达。它抑制CYP2D6、CYP1A2、CYP3A4和CYP2C9,也抑制Ca2+内流,有可能抑制或阻止肿瘤生长。 | |||
TN1286 |
5,6-Didehydroginsenoside Rd
5,6-Dehydroginsenoside Rd,5,6-二去氢人参皂苷 RD,5,6-脱氢人参皂苷Rd |
Others | Others |
5,6-Dehydroginsenoside Rd is a natural product | |||
TN1098 |
Ginsenoside Rd2
人参皂苷Rd2,Ginsenoside Rd2 (Quinquenoside L10) |
Others | Others |
Ginsenoside Rd2 (Quinquenoside L10) is a natural product with Nourish the strong, calm the mind, nourish the body. | |||
T13456 |
(S)-Willardiine
(-)-Willardiine,L-willardiine,Willardiine |
iGluR | Membrane transporter/Ion channel; Neuroscience |
(S)-Willardiine (L-willardiine) 存在于金合欢和含羞草的种子中。 (S)-Willardiine 是一种 AMPA/红藻氨酸受体激动剂 (EC50 = 44.8 μM)。 | |||
T5311 |
Crocin (Gardenia Fruits Extract)
藏红花,西红花苷 |
Others | Others |
Crocin (Gardenia Fruits Extract)(42553-65-1)是藏红花(Crocus sativus L.)的水溶性类胡萝卜素色素。藏红花素具有抗炎、抗氧化、抗凋亡、抗哮喘、抗癌、降血脂等作用。 | |||
T2994 |
(E)-Cardamonin
Alpinetin chalcone,Cardamomin,小豆蔻明,Cardamonin,(E)-Cardamoni,豆蔻明 |
Apoptosis; TRP/TRPV Channel | Apoptosis; Membrane transporter/Ion channel |
(E)-Cardamonin (Alpinetin chalcone) 是一种新型hTRPA1阳离子通道拮抗剂,IC50值为454 nM。 | |||
T3410 |
Momordin Ic
地肤子皂苷Ic,地肤子皂苷 Ic,Momordin 1c |
Apoptosis; MAPK; PI3K | Apoptosis; MAPK; PI3K/Akt/mTOR signaling |
Momordin Ic (Momordin 1c) 是山茱萸的主要皂苷成分,通过氧化应激调控线粒体功能障碍诱导细胞凋亡,具有抗癌活性。 | |||
T3421 |
Nordihydrocapsaicin
|
Others | Others |
Nordihydrocapsaicin(诺地氢辣椒碱)是Capsaicin(辣椒素)的模拟物和同源物,属于在Capsicum(辣椒)中发现的Capsaicinoid(辣椒素类)化合物。 | |||
TN2283 |
Tripterifordin
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Tripterifordin 在 H9 淋巴细胞中显示出抗 HIV 复制活性,EC50值为 3100 nM。 | |||
T2915 |
Bardoxolone
RTA 401,齐墩果烷三萜化合物,CDDO |
Others; Nrf2 | Immunology/Inflammation; Others |
Bardoxolone (CDDO) 是新型核调节因子激活剂。 | |||
T3S0175 |
Gardenia yellow
alpha-Crocin,Crocin I,Crocine,西红花苷 I,西红花苷I,藏红花 |
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Gardenia yellow (Crocin I) 是藏红花素家族的一员,作为可口服的抗抑郁剂,能增强 SIRT3的 mRNA 的表达,具有抗动脉粥样硬化和降血脂作用。 | |||
T6S1740 |
Nardosinone
苷松新酮,甘松新酮 |
Others | Others |
Nardosinone 是一个 dbcAMP 和 staurosporine 的神经生成作用增强剂,分离自Nardostachys chinensis 中。Nardosinone 可能成为一种有用的药理学工具,不仅可用于研究神经生长因子 (NGF) 的作用机理,而且可用于研究神经毒性物质的作用机理。 | |||
T3S2296 |
Gardenoside
羟异栀子苷,栀子苷 |
Others | Others |
Gardenoside 是一种发现于栀子中的天然化合物,具有保肝作用。它对 FFA 诱导的细胞脂肪变性有抑制作用。它可以调节 P2X3 和 P2X7 受体来抑制慢性缩痛。 | |||
TN4114 |
Gardenin A
|
ERK; LDL; MAPK; PKA; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; Tyrosine Kinase/Adaptors |
Gardenin A 通过激活 MAPK/ERK、PKC 和 PKA 表现出神经营养作用。 Gardenin A 具有抗抑郁、抗惊厥和抗焦虑作用。 | |||
T2890 |
Hordenine
|
Antibacterial; Antibiotic | Microbiology/Virology |
Hordenine 是一种植物中发现的苯乙胺生物碱,可抑制 cAMP 产生起到抑制黑色素生成的作用。 | |||
TN3594 |
Cardanol (C15:1)
|
Apoptosis; Others | Apoptosis; Others |
Cardanol (C15:1) 存在于腰果壳液中,可诱导人黑色素瘤细胞线粒体相关的细胞凋亡。 | |||
TN1675 |
Gardenin B
栀子黄素B |
Apoptosis; ROS; Caspase; NO Synthase | Apoptosis; Immunology/Inflammation; Proteases/Proteasome |
Gardenin B 是从Baccharis scandens 中分离出的一种黄酮类天然产物。它对肺、乳腺、结肠、肝和白血病细胞系以及角质形成细胞具有优异的抗增殖活性。 | |||
T6389 |
Anacardic Acid
漆树酸,6-pentadecylsalicylic Acid,Hydroginkgolic acid |
Others; Epigenetic Reader Domain; Histone Acetyltransferase; Antibacterial | Chromatin/Epigenetic; Microbiology/Virology; Others |
Anacardic Acid (6-pentadecylsalicylic Acid) 是从腰果壳中提取液中分离到的酸类物质,是一种组蛋白乙酰转移酶抑制剂,对 p300 和 PCAF 的 IC50值分别为 ∼8.5 μM 和 ∼5 μM。 | |||
T3S2325 |
Ardisiacrispin A
百两金素,Saxifragifolin B,LTS-4,Deglucocyclamin |
HSV | Microbiology/Virology |
Ardisiacrispin A (Deglucocyclamin) 是一种常见的三萜皂苷,来自于紫金牛属物种。 它与来自紫金牛属的 A. crenata 中的一些三萜皂苷具有相似的生物学特性,如对肿瘤细胞具有细胞毒活性、免疫调节和抗病毒活性。 | |||
TJS2190 |
Nordihydroguaiaretic acid
去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid |
Antioxidant; Ferroptosis; Lipoxygenase; Autophagy | Apoptosis; Autophagy; Metabolism; oxidation-reduction |
Nordihydroguaiaretic acid (NDGA) 是从极叉开拉瑞阿提取出的一种天然产物,是脂氧合酶抑制剂,具有抗氧化和清除自由基的特性。 | |||
TJS0328 |
Nordalbergin
6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素 |
Others | Others |
Nordalbergin 是一种香豆素,分离自Dalbergia sissoo 的木皮中。 它能够显著性的诱导 HL-60 细胞的分化。 | |||
T2993 |
Cordycepin
3'-Deoxyadenosine,虫草素 |
MMP; TNF; Antibacterial; Antibiotic; Autophagy | Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome |
Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物,在类风湿性关节炎滑膜成纤维细胞中,剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。 | |||
T3411 |
Curdione
莪术二酮,(+)-Curdione |
P450 | Metabolism |
Curdione ((+)-Curdione) 是一种具有高生物活性的倍半萜类物质,从莪术中分离获得,具有抑制血小板聚集、抵抗血栓形成的作用。 | |||
TN2629 |
15,16-Dihydro-15-methoxy-16-oxohardwickiic acid
|
Others | Others |
15,16-Dihydro-15-methoxy-16-oxohardwickiic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2629,CAS号为 115783-35-2。 | |||
TN5780 |
[4]-Gingerdiol
(3R,5S)-[4]-Gingerdiol |
||
[4]-Gingerdiol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5780,CAS号为 53254-75-4。 | |||
TN1946 |
Momordicoside L
|
Others | Others |
Momordicoside L has hypoglycaemic / antihyperglycaemic activities. | |||
TN4576 |
Momordicine II
|
Others | Others |
Momordicine II may have antidiabetic activity, it significantly stimulated insulin secretion. It also can deter oviposition by L. trifolii significantly. | |||
TN6867 |
Dehydrocurdione
|
||
Dehydrocurdione is a natural product. | |||
TN6510 |
Cordifolioside A
|
||
Cordifolioside A possesses immunomodulatory activity, it has a potential in vivo radioprotective effect as well as in vitro cytoprotective activity. | |||
T75481 | Guignardone L | ||
Guignardone L 是一种从内生真菌Guignardia mangiferae 中分离出来的代谢物,具有 toll 样受体 3 调节活性。 | |||
T40204 |
Wilfordinine D
|
||
Wilfordinine D is a natural sesquiterpene alkaloid. | |||
TN4315 |
Isonardosinone
|
NF-κB; MAPK | MAPK; NF-κB |
Isonardosinone shows potential role in the treatment of neuroinflammation conditions, it inhibits NF-κB- and MAPK-mediated inflammatory pathways. | |||
TN6906 |
1-Pentadecene [Standard Material for GC]
|
||
1-Pentadecene [Standard Material for GC] is a natural product. | |||
TN6453 |
Nardoaristolone B
|
||
Nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes. The novel mosquito-repellentsynthetic hydrindanesbased on noreremophilanes and nardoaristolone B which s | |||
TN4577 |
Momordicoside X
|
Others | Others |
Momordicoside X displays moderate insulin secretion activity. | |||
TN5771 |
(3S,5S)-[6]-Gingerdiol
|
||
(3S,5S)-[6]-Gingerdiol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5771,CAS号为 143615-76-3。 | |||
TN1944 |
Momordicoside I aglycone
|
Others | Others |
Momordicoside I aglycone is a natural product | |||
T82333 |
Gardenin C
|
||
Gardenin C, 一种黄酮化合物,具有从栀子中分离提取的能力。 | |||
T78495 |
Nordeoxycholic acid
3α,12α-Dihydroxynorcholanic acid |
||
Nordeoxycholic acid,一种含有23个碳原子的胆汁酸,是norcholic acid的代谢产物,也是人体固醇代谢的组成部分。 | |||
T71788 |
Hordenine hydrochloride
|
||
Hordenine hydrochloride is a biochemical that inhibits the activity of PDK3, inhibits quorum sensing, and acts as an antibiofilm agent against bacteria. | |||
TN1943 |
Momordicoside G
|
Others | Others |
Momordicosides K and L, the main bitter taste triterpene glycosides in Bitter melon; and bitter melon has been reported to have hypoglycemic, anti atherogenic and anti HIV activities. | |||
T75480 | Guignardone K | ||
Guignardone K,一种二萜化合物,从内生真菌(Guignardia sp.)的固体培养物中分离出来,具有抗真菌活性。 | |||
TN5754 |
[12]-Dehydrogingerdione
|
Others | Others |
[12]-Dehydrogingerdione 是存在于生姜中的天然产物,具有抗神经炎性的活性。 | |||
T72208 |
1-Dehydro-[10]-gingerdione
|
||
1-Dehydro-[10]-gingerdione 通过靶向IKKβ的激活环直接抑制 IKKβ 活性,从而破坏用激动剂刺激的巨噬细胞中 IKKβ 催化的 IκBα 磷酸化。1-Dehydro-[10]-gingerdione 抑制 LPS 诱导的NF-κB 转录活性。1-Dehydro-[10]-gingerdione 具有用于NF-κB 相关炎症和自身免疫性疾病研究的潜力。 | |||
TN4314 |
Isonardoperoxide
|
Antifection | Microbiology/Virology |
Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10-7 M). | |||
TN6241 |
Momordicin IV
|
||
Momordicin IV 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6241,CAS号为 894412-35-2。 | |||
TN5377 |
Nardoeudesmol A
|
||
Nardoeudesmol A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5377,CAS号为 1445952-30-6。 | |||
TN6949 |
6-Gingerdiol
|
||
6-Gingerdiol is a natural product. | |||
TN5765 |
[6]-Gingerdiol
(3R,5S)-[6]-Gingerdiol |
||
[6]-Gingerdiol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5765,CAS号为 154905-69-8。 | |||
TN1941 |
Momordicoside A
|
Others | Others |
Momordicoside A has the inhibition effect on PIP1B. | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00376 |
IL-17RD Protein, Human, Recombinant (hFc)
IL17Rhom,IL17RD,IL-17RD,IL-17 RD,... |
Human | HEK293 Cells |
Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. It may inhibit FGF-induced FGFR1 tyrosine phosphorylation, regulate the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK By similarity, and mediate JNK activation ... | |||
TMPY-03109 |
PHYH Protein, Human, Recombinant
PHYH1,RD,PAHX,LN1,phytanoyl-CoA 2-hydroxylase,LNAP1 |
Human | E. coli |
PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentos... | |||
TMPJ-01284 |
ERMAP Protein, Human, Recombinant (hFc)
Erythroid Membrane-Associated Protein,RD,ERMAP,Radi... |
Human | HEK293 Cells |
ERMAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number is Q96PL5. | |||
TMPJ-01285 |
ERMAP Protein, Human, Recombinant (His)
SC,RD,ERMAP,Scianna Blood Group Antigen,Radin Blood... |
Human | HEK293 Cells |
ERMAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is Q96PL5. | |||
TMPK-00895 |
Tubby Protein, Human, Recombinant (His)
TUB,RD5,RDOB |
Human | E. coli |
Tubby is the founding member of the tubby-like family of proteins. Tubby-like proteins (TLPs) possess a highly conserved closed β barrel tubby domain at C-terminal and N-terminal F-box.Tubby plays a critical role in trafficking select GPCRs to the cilia. | |||
TMPY-00844 |
IL-17RD Protein, Human, Recombinant (His)
IL-17RD,interleukin 17 receptor D,HH18,IL17RLM,SEF |
Human | HEK293 Cells |
IL-17RD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.5 kDa and the accession number is Q8NFM7-1. | |||
TMPY-00338 |
IL-17RD Protein, Canine, Recombinant (hFc)
interleukin 17 receptor D |
Canine | HEK293 Cells |
IL-17RD Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 58.2 kDa and the accession number is XP_541835.3. | |||
TMPJ-01215 |
IL-17RD Protein, Mouse, Recombinant (hFc)
Interleukin-17 receptor-like protein,IL-17 receptor D,IL-17<... |
Mouse | HEK293 Cells |
IL-17RD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-120 KDa and the accession number is Q8JZL1. | |||
TMPJ-01216 |
IL-17RD Protein, Mouse, Recombinant (His)
Sef,mSef,Interleukin-17 receptor-like protein,Il17rlm,Interl... |
Mouse | HEK293 Cells |
IL-17RD Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-65 KDa and the accession number is Q8JZL1. | |||
TMPY-00625 |
IL-17RD Protein, Canine, Recombinant (His)
interleukin 17 receptor D |
Canine | HEK293 Cells |
IL-17RD Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.6 kDa and the accession number is XP_541835.3. | |||
TMPY-06071 |
SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is YP_009725307.1. | |||
TMPJ-00694 |
BRD4 Protein, Human, Recombinant (His & Flag)
MCAP,HUNK1,HUNKI,bromodomain-containing protein 4 |
Human | E. coli |
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure. BRD bromodomains serve as recognition motifs for ... | |||
TMPH-00578 |
NrdD Protein, E. coli, Recombinant (His)
|
E. coli | E. coli |
Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 84.0 kDa and the accession number is P28903. | |||
TMPH-01049 |
Cardiac phospholamban/PLN Protein, Human, Recombinant (GST)
Cardiac phospholamban,PLN,PLB |
Human | P. pastoris (Yeast) |
Cardiac phospholamban/PLN Protein, Human, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 33.1 kDa and the accession number is P26678. | |||
TMPY-00114 |
Influenza A H12N1 (A/mallard duck/Alberta/342/1983) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H12N1 | Baculovirus Insect Cells |
Influenza A H12N1 (A/mallard duck/Alberta/342/1983) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is Q2FCE0. | |||
TMPH-00441 |
PRDX1 Protein, Cricetulus griseus, Recombinant (His)
|
Chinese hamster | P. pastoris (Yeast) |
PRDX1 Protein, Cricetulus griseus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9JKY1. | |||
TMPH-00204 |
Azurin Protein, Bordetella bronchiseptica, Recombinant (His & Myc)
BB3856,Azurin |
Bordetella bronchiseptica | E. coli |
Azurin Protein, Bordetella bronchiseptica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.8 kDa and the accession number is P0A321. | |||
TMPY-00174 |
Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H9N5 | Baculovirus Insect Cells |
Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.3 kDa and the accession number is Q20NF5. | |||
TMPH-02845 |
Properdin Protein, Mouse, Recombinant (His & Myc)
|
Mouse | HEK293 Cells |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). | |||
TMPH-02844 |
Properdin Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). | |||
TMPY-03226 |
Influenza A H14N5 (A/mallard/Astrakhan/263/1982) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H14N5 | HEK293 Cells |
Influenza A H14N5 (A/mallard/Astrakhan/263/1982) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa and the accession number is P26136. | |||
TMPJ-00933 |
PRDX5 Protein, Human, Recombinant (His)
Antioxidant enzyme B166,Alu corepressor 1,Peroxiredoxin-5,PL... |
Human | HEK293 Cells |
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/a... | |||
TMPY-01516 |
Influenza A H11N9 (A/mallard/Alberta/294/1977) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H11N9 | HEK293 Cells |
Influenza A H11N9 (A/mallard/Alberta/294/1977) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.7 kDa and the accession number is Q20NM3. | |||
TMPH-00821 |
EP-B2 Protein, Hordeum vulgare, Recombinant (His & SUMO)
Cysteine proteinase EP-B 2,EP-B2,EPB2 |
Hordeum vulgare | E. coli |
EP-B2 Protein, Hordeum vulgare, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is P25250. | |||
TMPH-03079 |
Sialidase Protein, Paeniclostridium sordellii, Recombinant (His & Myc)
|
Paeniclostridium sordellii | E. coli |
Sialidases have been suggested to be pathogenic factors in microbial infections. Sialidase Protein, Paeniclostridium sordellii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.2 kDa and the accession number is P15698. | |||
TMPH-03026 |
CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)
ADP-ribosylating toxin CARDS,CARDX TX,ADP-... |
Mycoplasma pneumoniae | E. coli |
Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells. | |||
TMPH-02579 |
CHRDL1 Protein, Mouse, Recombinant (His & Myc)
Nrln1,Neuralin-1,Ng1,Neurogenesin-1,Chrdl1,Ventropt... |
Mouse | Baculovirus Insect Cells |
Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the ind... | |||
TMPY-00398 |
Cardiotrophin 1 Protein, Human, Recombinant (hFc)
CT-1,CT1,cardiotrophin 1 |
Human | HEK293 Cells |
Cardiotrophin 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q16619-1. | |||
TMPJ-00524 |
SORD Protein, Human, Recombinant (His)
Sorbitol Dehydrogenase,L-Iditol 2-Dehydrogenase,SORD |
Human | HEK293 Cells |
Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regul... | |||
TMPH-02466 |
Ribonuclease MC Protein, Momordica charantia, Recombinant (His & Myc)
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Momordica charantia | E. coli |
Ribonuclease MC Protein, Momordica charantia, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.7 kDa and the accession number is P23540. | |||
TMPY-04186 |
Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H10N3 | HEK293 Cells |
Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.7 kDa and the accession number is C6Y4Y2. | |||
TMPH-01200 |
DRD1 Protein, Human, Recombinant (His)
Dopamine D1 receptor,DRD1,D(1A) dopamine receptor |
Human | E. coli |
DRD1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01201 |
DRD2 Protein, Human, Recombinant (His & Myc)
Dopamine D2 receptor,D(2) dopamine receptor,DRD2 |
Human | E. coli |
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5. | |||
TMPY-03599 |
RPRD1B Protein, Human, Recombinant (His)
C20orf77,regulation of nuclear pre-mRNA domain containing 1B... |
Human | HEK293 Cells |
RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phosphorylated RNAP II at target gene promoters. RNA polymerase II C-terminal domain (CTD) phosphorylation is important for various transcription-related processes. RPRD1B is a transcriptional regulator that enhances expression of CCND1. It also enhances the transcription of a number of... | |||
TMPH-00208 |
Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His)
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Bordetella pertussis | E. coli |
Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process. Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant ... | |||
TMPH-00951 |
PYCARD Protein, Human, Recombinant (His & Myc)
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Human | HEK293 Cells |
PYCARD Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is Q9ULZ3. | |||
TMPY-02271 |
TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)
thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12 |
Human | E. coli |
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th... | |||
TMPY-05941 |
Influenza A H3N2 (A/Amsterdam/4112/1992) Neuraminidase/NA Protein (His)
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Amsterdam/4112/1992) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is H9XD32. | |||
TMPY-02621 |
Influenza A H12N1 (A/mallard duck/Alberta/342/1983) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H12N1 | HEK293 Cells |
Influenza A H12N1 (A/mallard duck/Alberta/342/1983) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is Q2FCE0. | |||
TMPY-02625 |
Influenza A H4N4 (A/mallard duck/Alberta/299/1977) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H4N4 | HEK293 Cells |
Influenza A H4N4 (A/mallard duck/Alberta/299/1977) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q0A4G1. | |||
TMPH-00825 |
Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc)
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Domesticated barley | E. coli |
Mannose-specific lectin. Has a weak agglutinating activity against rabbit erythrocytes. Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22.6 kDa and the accession number is P82953. | |||
TMPH-00824 |
Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc)
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Hordeum vulgare | E. coli |
Releases hydrogen peroxide in the apoplast which may be important for cross-linking reactions in the cell wall biochemistry. May play an important role in several aspects of plant growth and defense mechanisms. Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the accession number is P45850. | |||
TMPY-03917 |
Cardiotrophin 1 Protein, Human, Recombinant
cardiotrophin 1,CT-1,CT1 |
Human | HEK293 Cells |
Cardiotrophin 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.2 kDa and the accession number is Q16619-1. | |||
TMPH-00083 |
Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
ERD14,Dehydrin ERD14 |
Arabidopsis thaliana | E. coli |
Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity. Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is P42763. | |||
TMPH-00822 |
DHN1 Protein, Hordeum vulgare, Recombinant (His & Myc)
DHN1,B8,Dehydrin DHN1 |
Hordeum vulgare | Baculovirus Insect Cells |
DHN1 Protein, Hordeum vulgare, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is P12951. | |||
TMPH-03080 |
Sialidase Protein, Paeniclostridium sordellii, Recombinant (hFc & Myc)
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Paeniclostridium sordellii | HEK293 Cells |
Sialidases have been suggested to be pathogenic factors in microbial infections. Sialidase Protein, Paeniclostridium sordellii, Recombinant (hFc & Myc) is expressed in HEK293 mammalian cells with C-hFC-Myc tag. The predicted molecular weight is 70.7 kDa and the accession number is P15698. | |||
TMPH-02178 |
TARDBP Protein, Human, Recombinant
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Human | E. coli |
TARDBP Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 44.9 kDa and the accession number is Q13148. | |||
TMPH-00823 |
Gamma-hordein-3 Protein, Hordeum vulgare, Recombinant (His & Myc)
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Hordeum vulgare | E. coli |
Has a role in the transport and targeting of prolamins to the vacuole of developing barley endosperm. Gamma-hordein-3 Protein, Hordeum vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.6 kDa and the accession number is P80198. | |||
TMPJ-00934 |
PRDX3 Protein, Human, Recombinant
Protein MER5 homolog,Thioredoxin-Dependent Peroxide Reductas... |
Human | E. coli |
Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with M... | |||
TMPY-04266 |
NAA10/ARD1 Protein, Human, Recombinant
NAA10,ARD1,ARD1A,ARD1P,NATD,TE2,N... |
Human | Baculovirus Insect Cells |
NAA10/ARD1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 26.6 kDa and the accession number is P41227. | |||
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