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Cat. No. | Product Name | ||
---|---|---|---|
DF4500 | 多样性核心库Part1 | 50000 compounds | |
绝大部分分子量<500,主要集中于250-450之间,方便后续的改造优化; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CEPY-0006 |
Human Cystatin SN/CST1 ELISA Pair Set
Human Cystatin SN/CST1 ELISA 抗体对 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19556 |
SAHA chloroalkane T1
|
Others | Others |
SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1. | |||
T73609 | Ribonuclease T1 | ||
Ribonuclease T1 (Rnase T1),常用于生化研究。Ribonuclease T1 是一种内切酶,可特异性降解单链 RNA。Ribonuclease T1 能够形成核苷 2′,3′-环磷酸中间体,以切割 3′-鸟苷残基与邻近核苷 5′-OH 基团之间的磷酸二酯键,产生 3′-GMP 末端寡核苷酸。 | |||
T11725 |
JNJ-47117096 hydrochloride
MELK-T1 hydrochloride |
Others | Others |
JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM. | |||
T82758 | CDK9-Cyclin T1 PPI-IN-1 | CDK | Cell Cycle/Checkpoint |
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) 是CDK9-Cyclin T1蛋白-蛋白相互作用的选择性抑制剂。该化合物能够有效抑制TNBC MDA-MB-231细胞系的细胞增殖(IC50: 0.044 μM),诱导细胞凋亡,同时降低CDK9的转录活性并减少RNA Pol II CTD ser2的磷酸化,有效地抑制了4T1移植瘤模型小鼠中肿瘤的生长。 | |||
T9104 |
TJ191
|
Apoptosis | Apoptosis |
TJ191 是一种选择性抗癌试剂,靶向低 TβRIII 表达的恶性T 细胞白血病/淋巴瘤细胞,可研究癌症。 | |||
T2029 |
Bohemine
|
ERK; CDK | Cell Cycle/Checkpoint; MAPK |
Bohemine 是一种合成的选择性CDK 抑制剂,是嘌呤类似物,具有抗癌活性。它对Cdk2/cyclin E、Cdk2/cyclin A 和Cdk9/cyclin T1的IC50分别为 4.6 μM、83 μM 和 2.7 μM。 | |||
T11820 |
LAT1-IN-1
2-氨基-2-去甲菠烷羧酸,BCH |
Apoptosis; Others | Apoptosis; Others |
LAT1-IN-1 (BCH) 是 L 型氨基酸转运蛋白 1 的选择性竞争性抑制剂,显着抑制细胞对氨基酸的摄取和 mTOR 磷酸化,从而诱导抑制癌症生长和细胞凋亡。 | |||
T16007 |
MALAT1-IN-1
|
Others | Others |
MALAT1-IN-1 是Malat1(转移相关的肺腺癌转录本 1) 的特异性抑制剂。它能够以剂量依赖性方式调节Malat1下游基因,但对Neat1(富核丰富转录本 1) 的表达无影响。 | |||
T4605 |
NT157
|
IGF-1R; STAT | JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
NT157 是一种口服生物可利用的间充质-上皮转化 (MET) TKI,主要针对具有 METex14 跳跃突变的特定 NSCLC 患者开发。 | |||
T6435 |
CCT129202
2-[4-[6-氯-2-(4-二甲基氨基苯基)-3H-咪唑并[4,5-B]吡啶-7-基]哌嗪-1-基]-N-(噻唑-2-基)乙酰胺 |
Aurora Kinase | Cell Cycle/Checkpoint; Chromatin/Epigenetic |
CCT129202 是一种 ATP 竞争性泛极光激酶抑制剂,作用于 Aurora A、Aurora B 和 Aurora C,IC50 分别为 0.042 μM、0.198 μM 和 0.227 μM。 | |||
T13059 |
T16Ainh-A01
|
Chloride channel | Membrane transporter/Ion channel |
T16Ainh-A01 是氨基苯基噻唑,是有效的跨膜蛋白 16A 的抑制剂,抑制 TMEM16A 介导的氯离子电流,IC50约为1 µM。TMEM16A (ANO1)起钙激活氯离子通道(CaCC)的作用。 | |||
T6303L |
CCT128930 hydrochloride
CCT128930 hydrochloride(885499-61-6 Free base) |
Apoptosis; Akt; PKA; mTOR; Autophagy | Apoptosis; Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
CCT128930 hydrochloride (CCT128930 hydrochloride) 是一种选择性 AKT 抑制剂,具有抗肿瘤活性。它通过靶向 AKT 的 Met282 (PKA-AKT 嵌合体的 Met173),对 PKA 激酶具有 28 倍的选择性,对 p70S6K 具有 20 倍的选择性。 | |||
T15017 |
CU-T12-9
|
TLR | Immunology/Inflammation |
CU-T12-9 是特异性 TLR1/2激动剂,可激活先天免疫系统和适应性免疫系统。它选择性激活 TLR1/2 异二聚体,可通过促进 TLR1 和 TLR2 二聚而激活 NF-κB 信号,引起下游 TNF-α、IL-10 和 iNOS 增加。 | |||
T2350 |
MALT1 inhibitor MI-2
MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor) |
MALT | Immunology/Inflammation |
MI 2 (MALT1 inhibitor) 是一种MALT1抑制剂 (IC50=5.84 μM),对动物无毒性。它能够直接与 MALT1 结合,不可逆地抑制蛋白酶功能,并伴有 NF-κB 报告子活性抑制、c-REL 核定位抑制和 NF-κB 靶基因下调。 | |||
T10168 |
5-HT1A modulator 1
5-HT1Amodulator1 |
Phospholipase; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Metabolism; Neuroscience |
5-HT1A modulator 1 对 5-HT1A、α1-肾上腺素能受体和 D2 受体具有非常高的亲和力(IC50s = 2 nM、10 nM 和 40 nM)。 | |||
T8842 |
IMT1B
3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-,LDC203974 |
Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
IMT1B (LDC203974) 是一种特异性的、具有口服活性的、非竞争性的线粒体 RNA 聚合酶 (POLRMT) 别构抑制剂,能够抑制线粒体 DNA (mtDNA) 的表达,具有抗肿瘤活性。 | |||
T2412 |
SRT1720 hydrochloride
SRT1720 HCl,SRT 1720 Hydrochloride |
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
SRT1720 hydrochloride (SRT1720 HCl) 是 SIRT1(EC1.5: 0.16 μM) 的选择性激活剂,对 SIRT2/SIRT3 (EC1.5s: 37 μM/300 μM) 的活性较低。 | |||
T9648 |
SIRT1-IN-1
|
Antiviral; Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation |
SIRT1-IN-1 是一种选择性的 SIRT1 抑制剂,IC50 为 205 nM。 SIRT1-IN-1 是一种具有抗病毒活性的巨细胞病毒 (CMV) 抑制剂。 | |||
T8779 |
HBT1
|
GluR | Neuroscience |
HBT1 是一种 AMPA 受体增强剂,可诱导脑源性神经营养因子 (BDNF) 的产生,并且在原代神经元中几乎没有激动作用。 HBT1 以谷氨酸依赖的方式与 AMPA-R 的配体结合结构域结合。 | |||
T2425 |
KPT185
KPT-185,KPT 185 |
CRM1 | Membrane transporter/Ion channel |
KPT185 (KPT 185) 是一种选择性 CRM1 抑制剂,可诱导细胞凋亡、细胞周期停滞。 | |||
T15000 |
Cort108297
|
Glucocorticoid Receptor | Endocrinology/Hormones |
Cort108297是一种选择性糖皮质激素受体调节剂,也是一种对其他类固醇受体无亲和力的选择性GR 拮抗剂。Cort108297对gr 具有较高的亲和力(Ki: 0.45 nM)。 | |||
T7947 |
FT113
|
Fatty Acid Synthase | Metabolism |
FT113 是口服具有活力的脂肪酸合酶抑制剂,对全长重组人 FASN 酶的 IC50=213 nM。在 BT474 细胞中,它抑制 FASN 的特性,IC50=90 nM。它具有抗增殖作用,在体内和体外实验中,都具有抗癌作用。 | |||
T9953 |
BT173
|
Others | Others |
BT173 是一种新型的同源域相互作用蛋白激酶 2 (HIPK2) 抑制剂,通过抑制 TGF-β1/Smad3 通路减轻肾纤维化。 | |||
T4133 |
CCT196969
|
Raf; Src | Angiogenesis; MAPK; Tyrosine Kinase/Adaptors |
CCT196969 是泛-Raf 抑制剂,抑制B-Raf、BRafV600E 和CRAF,IC50分别为 0.1、0.04、和 0.01 μM。 | |||
T10899 |
CU-CPT17e
|
TLR | Immunology/Inflammation |
CU-CPT17e 是多Toll 样受体激动剂,可激活TLR3、TLR8和TLR9。 | |||
T62512 |
IHMT-MST1-58
|
Hippo pathway | Stem Cells |
IHMT-MST1-58 是一种 STE20-like protein 1 kinase (MST1) 抑制剂(IC50 :23 nM),具有高效性、选择性和口服活性。IHMT-MST1-58 可用于研究 1 型或 2 型糖尿病。 | |||
T11784 |
KT182
|
MAGL | Metabolism |
KT182 是一个有效的、α/β 水解酶结构域 6 (ABHD6) 的选择性抑制剂,其在 Neuro2A 细胞中测得的 IC50 值为0.24 nM。 | |||
T67872 |
VT104
|
YAP | Stem Cells |
VT104是一种有效的YAP/TAZ 抑制剂,具有口服活性,可用于癌症研究。VT104阻止内源性TEAD1和TEAD3蛋白棕榈酰化。 | |||
T8448 |
ZSET1446
ZSET-1446,ST-101 |
Calcium Channel; AChR | Membrane transporter/Ion channel; Metabolism; Neuroscience |
ZSET1446 (ST-101) 是一种 T 型钙通道激活剂,用于治疗各类阿尔茨海默病 (AD) 模型中的学习缺陷。 | |||
T8841 |
IMT1
Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-,LDC195943(IMT1) |
Others; DNA/RNA Synthesis; Mitochondrial Metabolism | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others |
IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) 是一种非竞争特异性人类线粒体 RNA 聚合酶(POLRMT) 抑制剂,可引起 POLRMT 的构象变化,以剂量依赖性方式阻断底物结合和转录。它可降低脱氧核苷三磷酸水平和柠檬酸循环中间体,导致细胞氨基酸水平显著消耗,有用于线粒体转录等相关疾病的研究潜力。 | |||
T11064 |
DMT1 blocker 2
|
Others | Others |
DMT1 blocker 2 是一种二价金属转运蛋白 1 的直接抑制剂(IC50:0.83 μM)。它可以阻断体内肠细胞的铁摄取。 | |||
T8765 |
iGOT1-01
|
Others | Others |
iGOT1-01 是一种天冬氨酸转氨酶 1 (谷氨酸草酰乙酸转氨酶 1;GOT1) 抑制剂,在 GOT1/GLOX/HRP 测定中IC50为 11.3 μM,在 MDH 偶联 GOT1 酶法测定中IC50为 85 μM。它显示出抗癌活性。 | |||
T2482 |
AT13148
|
ROCK; SGK; Akt; PKA; S6 Kinase | Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors |
AT13148 是一种 ATP 竞争性 AGC 激酶口服抑制剂,能够抑制 Akt1/Akt2/Akt3、p70S6K、PKA 和 ROCKI/ROCKII 的活性,IC50值分别为 38/402/50、8、3 和 6 nM/4 nM。 | |||
T8408 |
GKT136901
AK120765 |
NADPH-oxidase; NADPH | Immunology/Inflammation; Metabolism |
GKT136901 (AK120765) 是选择性的和具有口服活性的 NADPH 氧化酶 NOX-1/4抑制剂,Ki 分别为 160 和 165 nM。它具有抗炎症活性。它也是一种选择性和直接的过氧亚硝酸清除剂。它可用于糖尿病肾病,中风和神经退行性疾病的研究。 | |||
T11063 |
DMT1 blocker 1
|
Others | Others |
DMT1 blocker 1 是二价金属转运蛋白1 (DMT1) 的阻断剂,IC50 为 0.64 μM,可以阻断体内肠细胞的铁摄取。 | |||
T11693L |
IT1t dihydrochloride
|
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
IT1t dihydrochloride 抑制 CXCL12/CXCR4 相互作用,IC50 为 2.1 nM。 IT1t dihydrochloride 是 CXCR4 的拮抗剂。 | |||
T14903 |
CCT129957
|
Calcium Channel; Phospholipase | Membrane transporter/Ion channel; Metabolism |
CCT129957 是一种新型有效的磷脂酶 C-γ (PLC-γ) 抑制剂,IC50 约为 3 μM,GC50 为 15 μM。CCT129957 具有抗癌活性,在鳞状细胞中抑制 Ca2+ 的释放。 | |||
T15109 |
DGAT1-IN-1
|
Transferase | Metabolism |
DGAT1-IN-1是 DGAT1的高效抑制剂,在 Hep3B 细胞过表达 DGAT1裂解物中,测得IC50低于10nM。 | |||
T23396 |
ST1936
ST 1936 oxalate |
5-HT Receptor | GPCR/G Protein; Neuroscience |
ST1936 (ST 1936 oxalate) 是一种具有选择性和高效性的 5-HT6 受体激动剂,抑制人 5-HT6、5-HT7 和 5-HT2B 受体,通过完全激活克隆的人 5-HT6 受体来刺激 cAMP、Ca2+、ERK1/2 和 Fyn 激酶。 | |||
T8766 |
GOT1 inhibitor-1
GOT1 inhibitor 2c |
Others | Others |
GOT1 inhibitor-1 (GOT1 inhibitor 2c) 是一种新型的、非共价的谷氨酸草酰乙酸转氨酶 1 (GOT1) 抑制剂(IC50:8.2 uM),是一种戊酸衍生物。 它可用于以及胰腺导管腺癌 (PDAC) 。 | |||
T2120 |
I-BET151
GSK1210151A |
Epigenetic Reader Domain | Chromatin/Epigenetic |
I-BET151 (GSK1210151A) 是 BRD2/3/4 的特异性 BET 抑制剂,IC50值分别为0.5、0.25、0.79 μM。 | |||
T77517 |
URAT1 inhibitor 7
|
OAT | Membrane transporter/Ion channel |
URAT1 inhibitor 7 是一种新型高效的人尿酸转运蛋白 URAT1 抑制剂 (IC50:12 nM)。URAT1 inhibitor 7 对 CYP2C9 具有抑制作用,IC50为4.2 μM。URAT1 inhibitor 7 可用于研究高尿酸血症和痛风。 | |||
T37197 |
5-HT1A modulator 2 hydrochloride
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
5-HT1A modulator 2 hydrochloride 是 8-OH-DPAT 的一种衍生物,是5-HT1A 的调节剂,Ki 为 53 nM。 | |||
T5183 |
AUT1
|
Potassium Channel | Membrane transporter/Ion channel |
AUT1 是 Kv3 钾离子通道调节剂,对人重组 Kv3.1b 和 Kv3.2a 的pEC50值分别为 5.33 和 5.31,对其活性是对人重组 Kv3.3 通道的 10 倍,pEC50值为 4.5。 | |||
T13587 |
BT18
|
Others | Others |
BT18 是一种功能类似于胶质细胞源神经营养因子的分子模拟物。它能够影响 GDNF 家族受体 GFRα1 和 RET 受体酪氨酸激酶 RetA 的功能。 | |||
T60129 |
MT189
Antiproliferative agent-14 |
Microtubule Associated | Cytoskeletal Signaling |
MT189 (Antiproliferative agent-14)是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂,IC50 为 3.41 μM。MT189 具有优异的抗增殖活性。Antiproliferative agent-14 具有在细胞周期的 G2/M 期阻滞细胞的能力。 | |||
T62077 |
VT103
VT-103,VT 103 |
YAP | Stem Cells |
VT103 是一种具有口服活性和选择性的 TEAD1 蛋白棕榈酰化抑制剂,是 VT101 的类似物。 VT103 有潜在的抗肿瘤活性,可抑制 YAP/TAZ-TEAD 促进的基因转录,阻断 TEAD auto-palmitoylation,阻断 YAP/TAZ和TEAD 之间的相互作用。VT103 可用于研究HER2阳性乳腺癌、前列腺癌和三阴性乳腺癌。 | |||
T4495 |
dBET1
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
dBET1 是一种由 BRD4 抑制剂 JQ1 与 NSC 527179 衍生物通过 linker 产生的 PROTAC,可诱导 BRD4 降解。它是由Cereblon 配体和BRD4配体相连的PROTAC,其EC50值为 430 nM。 | |||
T67727 |
MCT1-IN-3
|
Monocarboxylate transporter | Membrane transporter/Ion channel |
MCT1-IN-3是一种单羧酸转运蛋白1 (MCT1)抑制剂。溶质载体(SLC)单羧酸转运蛋白1 (MCT1);SLC16A1)是治疗癌症的一个有希望的靶点。MCT1-IN-3(化合物24)对MCT1转运抑制作用强,IC50值为81.0 nM。MCT1-IN-3对多药转运体ABCB1也有明显的抑制作用。 | |||
T27404 |
GAT107
GAT 107,GAT-107 |
AChR | Neuroscience |
GAT107 是一种新型有效的 α7 烟碱胆碱能受体变构激动剂和调节剂,具有抗炎活性,可逆转小鼠神经疼痛模型中的伤害感受。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T75632 | Ganoderic acid T1 | ||
Ganoderic acid T1是Ganoderic acid T的去乙酰化衍生物,具有促进癌细胞凋亡(apoptosis)的功能。它通过降低线粒体膜电位以及激活caspase-9和caspase-3来引发细胞凋亡,并增加细胞内ROS的产生,从而表现出促氧化活性和细胞性毒作用,同时减弱抗氧化防御系统。 | |||
T5761 |
Notoginsenoside Ft1
三七皂苷FT1,三七皂甙 Ft1 |
Others; HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; Metabolism; Others |
Notoginsenoside Ft1 是一种植物分离的三七皂苷,具有刺激血管生成的作用。 | |||
T4S1518 |
Pseudoginsenoside RT1
拟人参皂苷 RT1,假人参皂苷RT1 |
Others | Others |
Pseudoginsenoside RT1 是分离自 Randia siamensis 中,具有鱼毒素作用。它可导致血压下降、心率加快和子宫自发收缩力增加。 | |||
T81630 |
OAT1/3-IN-1
|
||
OAT1/3-IN-1(化合物7)是针对OAT1和OAT3的双重抑制剂。该化合物能逆转Cys-Hg(10 μM)对HEK-OAT1细胞引起的毒害,表明其对肾脏有潜在的保护效应。OAT1/3-IN-1适合用于探究汞引起的肾脏损伤机制研究。 | |||
T81629 |
OAT1/3-IN-2
|
||
OAT1/3-IN-2(化合物8)是一种针对OAT1和OAT3的双重抑制剂。该化合物能够以10 μM的浓度逆转Cys-Hg对HEK-OAT1细胞的毒害作用,并可能对肾脏具有保护效应。OAT1/3-IN-2适用于研究汞导致的肾脏损伤。 | |||
TMA0925 | Wilforlide A acetate | Others | Others |
Wilforlide A (T1) serves as a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. T1 has anti-inflammatory effects. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01235 |
CD5 Protein, Human, Recombinant (His)
LEU1,CD5 molecule,T1 |
Human | HEK293 Cells |
CD5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P06127. | |||
TMPY-04096 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (His)
Ly84,St2-rs1,T1,ST2L,T1/ST2,Fit-1,St2,inte... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P14719-1. | |||
TMPY-01359 |
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 receptor-like 1,... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2. | |||
TMPY-00849 |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2. | |||
TMPY-00850 |
ST2/IL-1 RL1 Protein, Human, Recombinant
ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2V,IL‑1 R4,interleu... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2. | |||
TMPJ-00850 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Protein T1,suppression of tumorigenicity 2,Ly84,DER... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPY-05422 |
CD5 Protein, Human, Recombinant (hFc)
CD5 molecule,LEU1,T1 |
Human | HEK293 Cells |
CD5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.4 kDa and the accession number is P06127. | |||
TMPY-05589 |
CD5 Protein, Human, Recombinant (His & Avi)
CD5 molecule,LEU1,T1 |
Human | HEK293 Cells |
CD5 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.9 kDa and the accession number is P06127. | |||
TMPY-01291 |
B4GALT1 Protein, Human, Recombinant (His)
B4GAL-T1,CDG2D,GT1,UDP-Gal:betaGlcNAc beta... |
Human | HEK293 Cells |
B4GALT1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.5 kDa and the accession number is P15291-1. | |||
TMPJ-00045 |
Podoplanin Protein, Human, Recombinant (hFc)
T1A,PDPN,GP36,Podoplanin,Aggrus,T1-α,PA2.2... |
Human | HEK293 Cells |
Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cy... | |||
TMPJ-00055 |
Podoplanin Protein, Mouse, Recombinant (hFc)
T1-alpha,PA2.26 antigen,T1A,Podoplanin, |
Mouse | HEK293 Cells |
Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. Detected at high levels in lung and brain, at lower levels in kidney, stomach, liver, spleen and esophagus, and not detected in skin and small intestine. Expressed in epithelial cells of choroid plexus, ependyma, glomerulus and ... | |||
TMPY-01095 |
Podoplanin Protein, Mouse, Recombinant (His & hFc)
T1a,T1-α,RANDAM-2,T1α,T1... |
Mouse | HEK293 Cells |
Podoplanin Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 40.6 kDa and the accession number is Q62011. | |||
TMPY-02659 |
Podoplanin Protein, Mouse, Recombinant (His)
T1a,T1-α,T1α,OTS-8,T1-al... |
Mouse | Baculovirus Insect Cells |
Podoplanin Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13 kDa and the accession number is Q62011. | |||
TMPY-04193 |
B3GNT1 Protein, Human, Recombinant (His)
iGNT,B3GN-T1,iGAT,β3GNTI,B3GNT6,BETA3GNTI,MDDGA13,B... |
Human | HEK293 Cells |
B3GNT1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.7 kDa and the accession number is A0A024R5F9. | |||
TMPK-00643 |
CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated
T1,LEU1,CD5,CD5 antigen,CD5 molecule |
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.7 kDa and the accession number is F6V5Q9. | |||
TMPY-03493 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc)
St2,ST2L,T1/ST2,interleukin 1 receptor-like 1,DER4,... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P14719-1. | |||
TMPK-00301 |
CD5 Protein, Human, Recombinant (hFc & Avi)
CD5 molecule,CD5,LEU1,CD5 antigen,T1 |
Human | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 67.1 kDa and the accession number is P06127. | |||
TMPK-00642 |
CD5 Protein, Rhesus macaque, Recombinant (His & Avi)
LEU1,T1,CD5,CD5 antigen,CD5 molecule |
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Rhesus macaque, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.7 kDa and the accession number is F6V5Q9. | |||
TMPK-00302 |
CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated
T1,LEU1,CD5 molecule,CD5 antigen,CD5 |
Human | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 67.1 kDa and the accession number is P06127. | |||
TMPK-00300 |
CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
T1,CD5,LEU1,CD5 antigen,CD5 molecule |
Mouse | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38.9 kDa and the accession number is P13379. | |||
TMPY-06809 |
B4GALT1 Protein, Mouse, Recombinant (His)
Ggtb,β4Gal-T1,B-1,4-GalT,GalT,β-1,4-GalT1,... |
Mouse | HEK293 Cells |
B4GALT1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.12 kDa and the accession number is P15535. | |||
TMPY-02147 |
ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His)
ST2L,FIT-1,IL‑1 R4,interleukin 1 receptor-like 1,ST2,DER4,IL... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.3 kDa and the accession number is Q01638-1. | |||
TMPH-03625 |
Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc)
Tityustoxin II,TsTX III-8,Toxin II,Tst2,Toxin T1-IV... |
Tityus serrulatus | Baculovirus Insect Cells |
Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 10.9 kDa and the accession number is P68410. | |||
TMPJ-00849 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)
Protein ST2,IL-1 R4,IL-33R,ST2V,suppression of tumorigenicit... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-110 KDa and the accession number is P14719-2. | |||
TMPY-04552 |
AKT1 Protein, Human, Recombinant (His)
RAC-ALPHA,v-akt murine thymoma viral oncogene homolog 1,RAC,... |
Human | Baculovirus Insect Cells |
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac... | |||
TMPY-05435 |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
angiopoietin 1,AGPT,AGP1,ANG1 |
Human | HEK293 Cells |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is Q15389-1. | |||
TMPY-06076 |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like... |
Human | HEK293 Cells |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1. | |||
TMPH-02151 |
OXCT1 Protein, Human, Recombinant (His)
|
Human | E. coli |
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. OXCT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.1 kDa and the accession number is P55809. | |||
TMPY-02062 |
SULT1A1 Protein, Human, Recombinant (His)
HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotrans... |
Human | E. coli |
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa... | |||
TMPY-00637 |
FLT1 Protein, Human, Recombinant (aa 1-328, His)
VEGFR-1,fms-related tyrosine kinase 1,VEGFR1,FLT,FLT-1 |
Human | HEK293 Cells |
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is L7RSL3. | |||
TMPY-00414 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)
ILT-11,CD85F,LIR-9,LIR9,LILRB7,CD85,ILT11,leukocyte... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1. | |||
TMPY-01037 |
CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
CSF-1R,CD115,HDLS,FIM2,M-CSF-R,MCSF Receptor,colony stimulat... |
Human | HEK293 Cells |
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P07333-1. | |||
TMPY-01442 |
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin |
Human | HEK293 Cells |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... | |||
TMPY-02805 |
GNGT1 Protein, Human, Recombinant (His)
guanine nucleotide binding protein (G protein), γ transducin... |
Human | E. coli |
GNGT1 is a subunit of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. They are involved as a modulator or transducer in various transmembrane signaling systems. G proteins are bound to GDP in the 'off' state. GNGT1 is the gamma subunit of transducin. Ligand-receptor binding results in detachment of the ... | |||
TMPY-01708 |
DOT1L Protein, Human, Recombinant
DOT1,KMT4,DOT1-like histone H3K79 methyltr... |
Human | E. coli |
Histone-lysine N-methyltransferase, H3 lysine-79 specific, also known as Histone H3-K79 methyltransferase, DOT1-like protein, Lysine N-methyltransferase 4 and DOT1L, is a nucleus protein which belongs to theDOT1 family. In contrast to other lysine histone methyltransferase, DOT1L does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones. DOT1L is an histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosome... | |||
TMPJ-01311 |
EPT1 Protein, Human, Recombinant (GST)
hEPT1,Selenoprotein I,SELI,EPT1,Ethanolami... |
Human | E. coli |
Ethanolaminephosphotransferase 1 (EPT1) is an enzyme that belongs to the CDP-Alcohol Phosphatidyltransferase Class-I Family. EPT1 is a Selenoprotein, which contains a Selenocysteine (Sec) residue at its active site. The Selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop sig... | |||
TMPY-02602 |
PTPMT1 Protein, Human, Recombinant (His)
protein tyrosine phosphatase, mitochondrial 1,MOSP,FLJ46081,... |
Human | E. coli |
PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion. It has been recently reported that PTPMT1 dephosphorylates phosphatidylglycerol phosphate, an essential intermediate of cardiolipin biosynthesis. PTPMT1 deficiency in mouse embryonic fibroblasts compromises mitochondrial respiration and results in abnormal mitochondrial morphology. Lipid analysis of PTPMT1-deficient fibroblasts reveals an a... | |||
TMPY-01660 |
SULT1E1 Protein, Human, Recombinant (His)
ST1E1,EST,sulfotransferase family 1E member 1,EST-1... |
Human | E. coli |
Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradio... | |||
TMPY-01343 |
FUT10 Protein, Human, Recombinant (His)
fucosyltransferase 10 (alpha (1,3) fucosyltransferase),fucos... |
Human | HEK293 Cells |
FUT10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.7 kDa and the accession number is Q6P4F1-1. | |||
TMPH-01580 |
KRT19 Protein, Human, Recombinant (His)
|
Human | E. coli |
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. KRT19 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.2 kDa and the accession number is P08727. | |||
TMPH-02137 |
FDFT1 Protein, Human, Recombinant (His)
|
Human | E. coli |
FDFT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 52.0 kDa and the accession number is P37268. | |||
TMPY-06417 |
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.22 kDa and the accession number is A0A6G7K2L4. | |||
TMPH-03748 |
KAT14 Protein, Human, Recombinant (His)
|
Human | E. coli |
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle. | |||
TMPY-06429 |
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 133.72 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-05291 |
CD57/B3gat1 Protein, Human, Recombinant (mFc)
LEU7,NK1,beta-1,3-glucuronyltransferase 1,HNK1,GLCATP,NK-1,β... |
Human | HEK293 Cells |
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited downstream integrin signaling, which was mimicked by knockdown of the core chondroitin sulfate synthesis enzymes β-1,3-glucuronyltransferase 1 (B3GAT1) and chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1). | |||
TMPH-02831 |
PLET1 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. | |||
TMPY-06532 |
ART1 Protein, Human, Recombinant (His)
ADP-ribosyltransferase 1,CD296,ARTC1,ART2,RT6 |
Human | HEK293 Cells |
ART1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.55 kDa and the accession number is NP_004305.2. | |||
TMPY-04398 |
MST1 Protein, Human, Recombinant (His)
serine/threonine kinase 4,KRS2,MST1,TIIAC,YSK3 |
Human | Baculovirus Insect Cells |
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker... | |||
TMPY-06252 |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.27 kDa and the accession number is A0A6G7K2L4. | |||
TMPH-02944 |
TCTP/TPT1 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Involved in calcium binding and microtubule stabilization. TCTP/TPT1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.5 kDa and the accession number is P63028. | |||
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