2206
153
1
226
Cat. No. | Product Name | ||
---|---|---|---|
L1380 | 转录因子库 | 695 compounds | |
695 种转录因子靶向、结构新颖的化合物; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T68122L |
Oxmetidine FA
Oxmetidine FA(72830-39-8 Free base) |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Oxmetidine FA 是一种可口服的特异性组胺 H2 受体拮抗剂,具有抗溃疡作用。 | |||
T6850L |
GSK2292767 FA
GSK2292767 FA(1254036-66-2 Free base) |
PI3K | PI3K/Akt/mTOR signaling |
GSK2292767 FA 是一种有效和选择性的 PI3Kδ 的抑制剂(pIC50 : 10.1)。GSK2292767 FA 的选择性是其他 PI3K 亚型的 500 倍以上。GSK2292767 FA 可用于研究呼吸系统疾病。 | |||
T25450L |
GGTI 2147 FA
GGTI2147 FA,GGTI-2147 FA,GGTI 2147 FA(191102-87-1 Free base) |
Others | Others |
GGTI 2147 FA 是一种选择性 GGT 抑制剂,在海马体实验中双库林诱导的树突棘密度增加被消除,可能会降低小鼠的学习和记忆能力。 | |||
T62396L |
KB-5492 FA
KB-5492 FA(113594-64-2 Free base) |
Sigma receptor | GPCR/G Protein |
KB-5492 FA 是一种有选择性 sigma 受体抑制剂,具有抗溃疡作用。 | |||
T27830L |
Lifarizine FA
Lifarizine FA(119514-66-8 Free base) |
Sodium Channel | Membrane transporter/Ion channel |
Lifarizine FA 是一种钠通道阻滞剂,可用于治疗神经系统疾病和心血管疾病,研究脑卒中。 | |||
T68129L1 |
Picumeterol FA
Picumeterol FA(130641-36-0 Free base) |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
picumeterol FA 是一种有效的选择性β2肾上腺素能受体激动剂。在体外和体内试验中,picumeterol FA 可产生持久的气道平滑肌松弛作用。picumeterol FA 是一种纯 R 对映异构体,可用于改善哮喘患者的肺功能和降低气道高反应性。 | |||
T68161L |
Tienoxolol FA
Tienoxolol FA (90055-97-3 Free base) |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Tienoxolol FA 是一种小分子 β-肾上腺素能受体拮抗剂,可用于治疗心血管疾病和研究高血压、心机缺血。 | |||
T64167L |
Ifebemtinib FA
BI-853520 FA(1227948-82-4 Free base) |
FAK | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Ifebemtinib FA (BI-853520 FA) 是一种具有口服活性和高效性的粘附斑激酶 (FAK) 抑制剂,具有抗癌抗增殖活性,可用于研究卵巢癌和肺癌。 | |||
T12344L1 |
OTS186935 FA
OTS186935 FA(2093400-18-9 Free base) |
Histone Methyltransferase | Chromatin/Epigenetic |
OTS186935 FA 是一种蛋白甲基转移酶 SUV39H2 抑制剂。OTS186935 FA在 MDA-MB-231 乳腺癌细胞和 A549 肺癌细胞中抑制肿瘤的生长。 | |||
T79500L |
KSK94 FA
KSK94 FA(2566716-07-0 Free base) |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
KSK94 FA 是一种高效的组胺 H3 受体拮抗剂,抑制 H3 受体,可用于研究神经性疼痛和肥胖症。 | |||
T64357 |
FA16
FA 16,FA-16 |
Ferroptosis | Apoptosis |
FA16 是一种选择性、代谢稳定的铁死亡 (ferroptosis) 诱导剂 ,IC50 值为1.26 μM。FA16 是 2-(三氟甲基) 苯并咪唑的衍生物。FA16 对胱氨酸/谷氨酸反转运蛋白 (system Xc-) 介导了细胞内谷氨酸和细胞外胱氨酸的交换有抑制作用。FA16 在 HepG2 异种移植瘤模型中显著抑制肿瘤生长。 | |||
T16090L |
MK-0773 FA
MK-0773 FA (606101-58-0 Free base) |
Androgen Receptor | Endocrinology/Hormones |
MK-0773 FA (MK-0773 FA (606101-58-0 Free base)) 是一种选择性雄激素受体调节剂 ,对 AR 的 IC50 值为 6.6 nM,可用于预防和治疗与癌症相关的肌肉萎缩。 | |||
T27158L |
DF-1012 FA
DF-1012 FA(163220-65-3 Free base) |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
DF-1012 FA 是一种 DF-1012 的结构类似物,是一种神经肽类抑制剂,可用于研究哮喘和咳嗽。 | |||
T19525L |
PPA-904 FA
PPA-904 FA(30189-85-6 Free base) |
Antibiotic | Microbiology/Virology |
PPA-904 FA 是一种阳离子光敏剂,具有广谱的抗菌活性,可用于光动力研究 (PDT) 研究,可用于研究慢性腿部溃疡和糖尿病足溃疡。 | |||
T12054L |
MK-0249 FA
MK-0249 FA(862309-06-6 Free base) |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
MK-0249 FA 是一种具有口服活性、选择性和高效性的组胺 H3 反向激动剂,可用于研究成人注意力缺陷、多动症神经分裂和认知障碍。 | |||
T6738 |
Z-FA-FMK
|
SARS-CoV; Cysteine Protease | Microbiology/Virology; Proteases/Proteasome |
Z-FA-FMK 是一种广谱的卤代甲基酮抑制剂,可抑制冠状病毒蛋白酶3CL,Ki 为 25.7 μM。它可以不可逆地抑制半胱氨酸蛋白酶,也可以抑制效应半胱天冬酶。 | |||
T31740 |
FA-alkyne
FA alkyne,FAalkyne |
||
FA-alkyne is a novel clickable fumarate-competitive chemoproteomic probe | |||
T71856 |
FA-613
|
||
FA-613 is a pyrimidine synthesis inhibitor which exhibits low micromolar antiviral activity against various influenza A and B virus strains, including the highly pathogenic influenza A strains H5N1 and H7N9, enterovirus A71, respiratory syncytial virus, human rhinovirus A, SARS- and MERS-coronavirus. | |||
T83971L |
LCC-12 FA
|
Antiviral; Antibacterial | Immunology/Inflammation; Microbiology/Virology |
LCC-12 FA 是一种由二甲双胍组成的二聚体,通过靶向线粒体铜 (ii) 从而诱导 NAD(H) 池减少。LCC-12 FA 可减少细菌和病毒感染小鼠模型中的炎症,可用于研究代谢疾病。 | |||
T62380L |
20-HC-Me-Pyrrolidine FA
|
Others | Others |
20-HC-Me-Pyrrolidine FA 是一种有效的 Aster 蛋白抑制剂,对 Aster-A、Aster-B 和 Aster-C 具有抑制作用,抑制 Aster 蛋白结合和转移胆固醇。20-HC-Me-Pyrrolidine FA 可用于研究脂类代谢。 | |||
T31781 |
Fentonium bromide
Z 326,FA 402 |
||
Fentonium bromide is a biochemical. | |||
T77767L |
GLF16 FA
|
||
GLF16 FA 是一种亲水性荧光 SBB 类似物,可使用流式细胞术和活细胞分选来快速检测衰老细胞。 | |||
T75144 | WU-FA-01 | ||
WU-FA-01,一种WU-FA-00的氢化衍生物,体现为针对革兰氏阳性菌株具有高效抗菌功能的抗菌剂,同时展现出抗炎活性。 | |||
T80114 |
FA-Ala-Arg
|
Endogenous Metabolite | Metabolism |
FA-Ala-Arg是一种携带呋喃丙烯酰基的二肽,它能够分解产生精氨酸,并因此提高精氨酸水平,后者可转化为一氧化氮(NO)。该化合物还可增强MCF-7细胞产生NO的能力,并在催乳素(PRL)处理下提升细胞存活率,其中PRL会调节CPD mRNA的表达。 | |||
T67824L |
3-([2,2':5',2'':5'',2'''-quaterthiophen]-5-yl)propan-1-amine FA
|
||
3-([2,2':5',2'':5'',2'''-quaterthiophen]-5-yl)propan-1-amine FA 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67824L。 | |||
T7556 |
Fadrozole hydrochloride
CGS 16949A,盐酸法倔唑 |
Aromatase | Endocrinology/Hormones |
Fadrozole hydrochloride (CGS 16949A) 是一种选择性的、有效,和非甾体类的芳香化酶抑制剂(IC50:6.4 nM)。 | |||
T3125 |
Amikacin sulfate
Amikacin Sulfate Salt,阿米卡霉素硫酸,硫酸阿米卡星 |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Amikacin sulfate 是一种氨基糖苷类抗生素,也是卡那霉素的半合成类似物。它具有杀菌作用,直接作用于 30S 和 50S 细菌核糖体亚基,可抑制蛋白质合成。它抑制大多数革兰氏阴性细菌,还抑制易感诺卡氏菌和非结核分枝杆菌引起的感染。 | |||
T40580 |
17β-Estradiol sulfate sodium
17β-Estradiol 3-sulfate sodium |
Antibiotic | Microbiology/Virology |
17β-Estradiol sulfate sodium (17β-Estradiol 3-sulfate sodium) 是一种神经活性雌激素,具有血管保护作用,可抑制巴西奈瑟菌的生长,破环水生生态系统。 | |||
TP1015 |
NFAT Inhibitor
VIVIT peptide |
Others | Others |
NFAT Inhibitor (VIVIT peptide) 是NFAT 的细胞渗透性肽抑制剂,能够选择性抑制钙调磷酸酶介导的NFAT 脱磷酸作用。 | |||
TP1029 |
Thymalfasin
胸腺法新,Thymosin α1,醋酸胸腺α1 |
Others | Others |
Thymalfasin (Thymosin α1) 是一种免疫调节化合物,可增强 Thl 的免疫应答。 | |||
T64341 |
H-β-Ala-AMC TFA
|
Others | Others |
H-β-Ala-AMC TFA 是氨基肽酶的底物之一。 | |||
T76251L |
Ac-FEID-CMK TFA
|
Pyroptosis | Apoptosis; Immunology/Inflammation |
Ac-FEID-CMK TFA 是一种选择性斑马鱼 GSDMEb 衍生肽抑制剂,可减少感染性休克的死亡率和肾损伤。Ac-FEID-CMK TFA 在体内可抑制焦亡,缓解败血性 AKI (急性肾损伤),抑制 caspy2 介导的非典型炎症小体通路发挥作用。 | |||
TP1622 |
DX600 TFA
|
RAAS | Endocrinology/Hormones |
DX600 TFA 是 ACE2 的特异性抑制剂,不会与 ACE 发生交叉反应。 | |||
T18901 |
6-FAM SE
6-羧基荧光素琥珀酰亚胺醚,6-Carboxyfluorescein N-succinimidyl ester |
Others | Others |
6-FAM SE (6-Carboxyfluorescein N-succinimidyl ester) 是羧基荧光素的同分异构体,常用于核酸测序和标记核苷酸。 | |||
TP2036L |
DPDPE TFA (88373-73-3 free base)
DPDPE TFA |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
DPDPE TFA 是选择性 δ-阿片受体激动剂肽,在体内具有镇痛作用。 | |||
T4350 |
Palifosfamide
ZIO-201,Isophosphamide mustard,帕利伐米,Isophosphoramide mustard |
DNA Alkylator/Crosslinker; DNA Alkylation; Drug Metabolite | DNA Damage/DNA Repair; Metabolism |
Palifosfamide (Isophosphamide mustard) 是一种新 DNA 烷化剂,是异环磷酰胺的活性代谢物,。它在体外肉瘤细胞系中具有广泛的活性,具有抗癌活性。 | |||
TQ0053 |
Fadraciclib
CYC065 |
CDK | Cell Cycle/Checkpoint |
Fadraciclib (CYC065) 是一种口服有效的 ATP 竞争性的CDK2/CDK9激酶抑制剂,IC50分别为 5 和 26 nM。 | |||
T17159 |
Treosulfan
NSC 39069,曲奥舒凡,Treosulphan |
DNA Alkylator/Crosslinker; DNA Alkylation | DNA Damage/DNA Repair |
Treosulfan (Treosulphan) 是一种双功能的烷化剂,对卵巢癌及其他的实体瘤都有抑制效果。 | |||
T40864 |
Magnesium sulfate
|
Others | Others |
Magnesium sulfate 是目前预防和控制子痫发作的抗惊厥剂。Magnesium sulfate 也被广泛用作宫缩剂。 | |||
T17172 |
Trofosfamide
|
Antibacterial | Microbiology/Virology |
Trofosfamide 是一种具有抗肿瘤效力的恶氮膦衍生物。 | |||
T8768 |
MM-102 TFA
HMTase Inhibitor IX TFA |
Histone Methyltransferase | Chromatin/Epigenetic |
MM-102 TFA (HMTase Inhibitor IX TFA) 是一种有效的 WDR5/MLL 相互作用抑制剂,在 WDR5 结合检测中,IC50为 2.4 nM,Ki 小于 1 nM。 | |||
T11237L |
Camizestrant TFA
Camizestrant TFA(2222844-89-3 Free base),AZD-9833 TFA |
Estrogen Receptor/ERR | Endocrinology/Hormones |
Camizestrant TFA (AZD-9833 TFA) 是一种有效的口服雌激素受体拮抗剂。 | |||
T30191L |
Atecegatran TFA
Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA |
Others | Others |
Atecegatran TFA 常被当作一种抗凝血剂,可用来治疗心血管疾病。 | |||
T29687 |
Afacifenacin
Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986 |
AChR | Neuroscience |
Afacifenacin (SMP-986) fumarate 是一种 M3 毒蕈碱受体选择性拮抗剂,可用于研究缺血性心脏病,尿失禁和膀胱炎和其他疾病。 | |||
T25364L |
Efegatran sulfate
LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate |
Thrombin | Proteases/Proteasome |
Efegatran sulfate (LY294468 sulfate) 是一种有效的凝血酶抑制剂,可用于治疗血栓类疾病。 | |||
T27303 |
Farglitazar
GI-262570,GI-2570,GW 262570X,GI 262570,GI262570 |
PPAR | DNA Damage/DNA Repair; Metabolism |
Farglitazar (GI-262570) 是一种 PPAR-γ 激动剂,是胰岛素增敏剂,通过氧化物酶体增殖物激活受体γ,抑制星状细胞活化,可用于研究糖尿病。 | |||
TP1793L |
Nociceptin (1-13) amide TFA
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Nociceptin (1-13) amide TFA (178064-02-3 free base) 是一种有效的 Opioid receptor-like1 (ORL1) receptor 激动剂,对小鼠输精管的 pEC50 为 7.9,与大鼠前脑膜结合的 Ki 为 0.75 nM。 | |||
TP1106L |
α-Factor Mating Pheromone, yeast acetate
Mating Factor α acetate,α-Factor Mating Pheromone, yeast acetate(59401-28-4 free base) |
Others | Others |
α-Factor Mating Pheromone, yeast acetate (Mating Factor α acetate)(59401-28-4 free base) 是由酿酒酵母α细胞分泌的13个氨基酸的肽。 | |||
TP1904L |
FSLLRY-NH2 TFA(245329-02-6 free base)
|
Protease-activated Receptor | GPCR/G Protein |
FSLLRY-NH2 TFA(245329-02-6 free base) 是一种蛋白酶激活受体 2 (PAR2) 抑制剂。在 ICR 小鼠中逆转紫杉醇诱导的机械异常性疼痛、热痛觉过敏和 PKC 激活。阻断分离的心脏成纤维细胞中的 ERK 活化和胶原蛋白生成。还可以减轻皮肤癣菌相关瘙痒小鼠模型的症状。 | |||
TP1918L |
Lys-[Des-Arg9]Bradykinin,TFA
Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa) |
Bradykinin Receptor | GPCR/G Protein |
Lys-[Des-Arg9]Bradykinin,TFA (71800-36-7 free base) 是内源性强效和高选择性的缓激肽 B1 受体激动剂(对人 B1 和 B2 受体的 Ki 值分别为 0.12 和 > 30000 nM)。降低体内外周血管阻力的降压药。比 [Des-Arg9]-缓激肽强 16 倍。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3S1589 |
Notoginsenoside Fa
|
Others | Others |
Notoginsenoside Fa 是一种原人参二醇型皂苷,从P. notoginseng 提取出来得到,有激活和恢复退化脑功能的潜能。 | |||
T19608 |
Zinc sulfate heptahydrate
|
Others | Others |
Zinc sulfate heptahydrate 是七水合形式的硫酸锌,是一种膳食补充剂,可用于锌缺乏症和预防高危人群的锌缺乏症。 | |||
T4860 |
5-Hydroxytryptamine creatinine sulfate monohydrate
Serotonin creatinine sulfate monohydrate,5-Hydroxytryptamine creatinine sulfate complex,5-五羟色胺肌酸酐 |
Others; Endogenous Metabolite | Metabolism; Others |
5-Hydroxytryptamine creatinine sulfate monohydrate (Serotonin creatinine sulfate monohydrate) 是内源性代谢产物的一种。 | |||
T2809 |
(R)-Fangchinoline
防己醇灵,Thaligine,(+)-Thalrugosine,Demethyl tetrandrine |
FAK; Antibacterial; Antibiotic | Angiogenesis; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors |
(R)-Fangchinoline ((+)-Thalrugosine) 是一种来自Stephania 属的生物碱,具有抗菌和降血压活性。它可用作中药,可用于发烧,腹泻,消化不良和泌尿疾病的研究。 | |||
T5S2178 |
Fargesin
辛夷脂素,(+/-)-Fargesin |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Fargesin ((+/-)-Fargesin) 是一种活性新木脂素,从木兰植物中分离得到,具有抗高血压和抗炎活性。 | |||
T26366 |
Dehydroepiandrosterone sulfate
PB 005,PB005,Prasterone sulfate,DHEA sulfate,DHEAS,PB-005 |
Others | Others |
Dehydroepiandrosterone sulfate (PB-005) 影响神经元的迁移、树突的分枝和新突触的形成。 | |||
T8074 |
Esafosfan trisodium
Fosfructose trisodium,D-果糖-1,6-二磷酸三钠盐,D-Fructose-1,6-diphosphate trisodium salt octahydrate,FDP trisodium,Diphosphofructose trisodium |
Others; Endogenous Metabolite | Metabolism; Others |
Esafosfan trisodium (FDP trisodium) 是一种细胞保护性的天然糖磷酸盐,用于镰状细胞性贫血,心血管缺血和哮喘的研究。Fosfructose trisodium 通过刺激无氧糖酵解起作用,其在缺血条件下产生三磷酸腺苷。 | |||
T4S1619 |
L-Hyoscyamine sulfate
Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐 |
AChR | Neuroscience |
L-Hyoscyamine sulfate (Levsin Sulfate) 是来自山莨菪的一种托烷生物碱,是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。 | |||
T12536 |
Pregnenolone monosulfate
3β-Hydroxy-5-pregnen-20-one monosulfate |
NMDAR | Neuroscience |
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) 是一种强效神经类固醇,可正向调节 NMDA 记录,可用于研究神经分裂和抑郁症。 | |||
TN1634 |
Euphorbia factor L7b
千金子素L7B |
Others | Others |
Euphorbia factor L7b 是从大戟属植物大戟中提取的天然产物。 | |||
T2S0410 |
Euphorbia factor L1
Euphorbiasteroid,大戟因子L1,大戟因子 L1 |
Apoptosis; P-gp | Apoptosis; Membrane transporter/Ion channel; Neuroscience |
Euphorbia factor L1 (Euphorbiasteroid) 可降低 Bcl-2,PI3K,AKT 和 mTOR 蛋白和 mRNA 水平,上调 caspase-9 and caspase-3 蛋白水平。它可诱导自噬,具有抗癌、抗脂肪生成、抗破骨细胞生成和多重耐药调节作用。 | |||
T125211 |
Deoxy euphorbia factor L1
|
Others | Others |
Deoxy euphorbia factor L1是一种天然产物,存在于植物续随子 Euphorbia lathyris L 的种子中。 | |||
TN7170 |
Sodium N-Octadecyl Sulfate
Sodium octadecyl sulfate,Sodium stearyl sulfate,十八烷基酯硫酸钠盐 |
Others | Others |
Sodium N-Octadecyl Sulfate (Sodium octadecyl sulfate) 是一种海洋来源的天然产物,存在于Aplidium turbinatum。 | |||
T1270 |
Vincristine sulfate
Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate,硫酸长春新碱 |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Vincristine sulfate (Leurocristine sulfate) 是一种抗肿瘤长春花生物碱。在细胞周期的 S 期不可逆地与微管(Ki: 85 nM) 和纺锤体蛋白结合,并干扰有丝分裂纺锤体的形成。 | |||
TN7168 |
Farnesylacetone
(5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one,法尼基丙酮,Farnesyl acetone,E,E-farnesylacetone |
Others | Others |
Farnesylacetone ((5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one) 是一种海洋来源的天然产物,存在于Sargassum micracanthum。 | |||
T41031 |
Protamine sulfate
|
Thrombin | Proteases/Proteasome |
Protamine sulfate是一种多阳离子肽类,作为一种抗肝素剂。该化合物能中和肝素的抗凝作用并增强脂质介导的基因转移。 | |||
T5798 |
Euphorbia Factor L2
千金子素L2,euphorbiafactor L2,大戟因子L2 |
Apoptosis; NF-κB | Apoptosis; NF-κB |
Euphorbia Factor L2 是从大戟种子中分离得到的一种赤藓烷二萜,显示强烈的细胞毒性并通过线粒体途径诱导细胞凋亡,具有抗癌活性。 | |||
T6S0525 |
Farrerol
|
ERK; p38 MAPK; Akt | Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling |
Farrerol 是一种杜鹃花的生物活性成分,具有抗氧化、抗肿瘤、抗炎、神经保护和肝保护等多种功能。 | |||
T4808 |
Agmatine sulfate
Agmatine sulfate salt,硫酸胍基丁胺 |
Endogenous Metabolite; NO Synthase; Imidazoline Receptor | Immunology/Inflammation; Metabolism; Neuroscience |
Agmatine sulfate (Agmatine sulfate salt) 是咪唑啉受体的内源性激动剂和一氧化氮合酶抑制剂。它靶向神经递质系统,离子通道和一氧化氮合成。 | |||
T1214 |
Ribostamycin sulfate
Vistamycin sulfate,硫酸核糖霉素 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ribostamycin sulfate (Vistamycin sulfate) 是一种广谱抗菌剂, 在30S 和50S 核糖体亚基结合抑制细菌蛋白质合成, 还抑制蛋白二硫键异构酶分子伴侣活性, 用于药代动力学和肾毒性研究。 | |||
T1245 |
Colistin sulfate
Colistin sulfate (1066-17-7 free base),Polymixin E Sulfate,Polymyxin E Sulfate,硫酸粘杆菌素 |
Cell wall; Antibacterial; Antibiotic; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology |
Colistin sulfate (Colistin sulfate (1066-17-7 free base)) 是抑制革兰氏阴性细菌的一种多肽抗生素,与革兰氏阴性细菌的外细胞膜中的脂多糖和磷脂结合起作用。 | |||
T0461L |
Berberine sulfate
AI3-61947,Berberin sulfate,Berberine sulphate,Berberal |
||
Berberine sulfate (Berberal) 是苄基异喹啉生物碱原小檗碱类的季铵盐,可用于研究2型糖尿病、腹部肥胖和代谢相关脂肪性肝病。 | |||
T10233 |
Acetylarenobufagin
|
HIF | Angiogenesis; Chromatin/Epigenetic |
Acetylarenobufagin 是一种类固醇缺氧诱导因子-1 (HIF-I) 调节剂。 | |||
T1084 |
Apramycin sulfate
Nebramycin II,Ai3-29795,硫酸安普霉素,硫酸阿布拉霉素 |
Antibacterial; Antibiotic | Microbiology/Virology |
Apramycin sulfate (Nebramycin II) 是一种由黑暗链霉菌产生的兽用氨基糖苷类抗生素。 | |||
T5003 |
Rifamycin sodium
Rifamycin sodium salt,利福霉素钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Rifamycin sodium (Rifamycin sodium salt) salt 是从地中海曲霉或其突变体的发酵中分离出来的一种安沙霉素抗生素家族。它对革兰氏阳性菌和某些革兰氏阴性菌有抗生素活性。 | |||
TN1635 |
Euphorbia factor L8
|
Others | Others |
Euphorbia factor L8 是大戟种子中的二萜。 | |||
T22293 |
Chondroitine sulfate
Chondroitine sulfate (From cattle) |
Others | Others |
Chondroitine sulfate 是软骨的重要结构成分,已被用作治疗关节不适的膳食补充剂。 | |||
T6369 |
Adenine hemisulfate
硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐 |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Adenine hemisulfate (Diadenine sulphate) 是一种嘌呤,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
T5S1285 |
(+)-(3R,8S)-Falcarindiol
Falcarindiol,镰叶芹二醇 |
Others | Others |
(+)-(3R,8S)-Falcarindiol 是一种从胡萝卜中得到的聚乙炔,有抗炎、抗肿瘤和抗脂质过氧化活性。它具有抗分歧杆菌作用,对Mycobacterium tuberculosisH37Ra 的 MIC 和 IC50值分别为 24 μM 和 6 μM。 | |||
TQ0298 |
Fagomine
D-Fagomine |
ROS; glycosidase | Immunology/Inflammation; Metabolism |
Fagomine (D-Fagomine) 是一种温和的糖苷酶 (glycosidase) 抑制剂,是1-脱氧野尻霉素 (DNJ) 的类似物,具有降血糖活性,Fagomine 降低了细胞内活性氧(ROS)的产生和丙二醛(MDA)水平。 | |||
TN1640 |
Fabiatrin
|
Others | Others |
Fabiatrin 是从 Przewalskia tangutica 的正丁醇提取物中分离和鉴定的天然产物。 | |||
T0792 |
(-)-Sparteine sulfate pentahydrate
(-)-Sparteine Sulfate,Lupinidine sulfate pentahydrate,(-)-Sparteine sulfate salt,sulfate pentahydrate,五水合硫酸司巴丁 |
Sodium Channel | Membrane transporter/Ion channel |
(-)-Sparteine sulfate pentahydrate ((-)-Sparteine Sulfate) 是一种生物碱,是钠通道抑制剂,属于1a 类抗心律失常药。 | |||
T5239 |
Cholesteryl sulfate sodium
Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate |
Endogenous Metabolite; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism |
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) 是内源性代谢产物的一种。 | |||
T1668 |
Vinblastine sulfate
硫酸长春碱,NSC49842,Vincaleukoblastine sulfate salt |
Microtubule Associated; AChR; Autophagy | Autophagy; Cytoskeletal Signaling; Neuroscience |
Vinblastine sulfate (Vincaleukoblastine sulfate salt) 是对各种癌症类型有细胞毒性的生物碱。 它可以抑制微管的形成,也可以抑制 nAChR,IC50值为8.9 μM。 | |||
T1326 |
Gentamicin sulfate
SCH9724,Gentamycin sulfate,NSC-82261,硫酸庆大霉素 |
ribosome; DHFR; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Gentamicin sulfate (SCH9724) 是一种广谱氨基糖苷类抗生素,用于抑制敏感生物体中的蛋白质合成。 | |||
T22583 |
Arcaine sulfate
|
NMDAR | Neuroscience |
Arcaine sulfate 是一种多胺,是 N-甲基-d-天冬氨酸 (NMDA) 受体多胺结合位点的拮抗剂。 Arcaine 是一种胍丁胺类似物,与 ifenprodil 一起,可能有可能用于治疗癫痫疾病。 | |||
T8028 |
Farnesyl acetate
Farnesyl Acetate (mixture of isomers),3,7,11-三甲基-2,6,10-十二烷三烯-1-醇乙酸酯,乙酸法呢醇酯 |
Others | Others |
Farnesyl acetate (Farnesyl Acetate(mixture of isomers)) 是一种倍半萜,分离自 Amomum gagnepainii 中。它对红棕榈象虫幼虫有显著的毒性(LD50:7867 ppm)。 | |||
T3122 |
Fangchinoline
Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline |
Apoptosis; FAK; HIV Protease; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。 | |||
T7203 |
Oglufanide
奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH |
VEGFR; HCV Protease; Endogenous Metabolite | Angiogenesis; Metabolism; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Oglufanide (H-Glu-Trp-OH) 是一种从小牛胸腺中分离出来的二肽免疫调节剂,可抑制血管内皮生长因子,可刺激细胞内细菌感染和对丙型肝炎病毒的免疫反应。 | |||
T1719 |
Bufalin
|
ATPase | Membrane transporter/Ion channel |
Bufalin 是蟾酥中的一种成分,是Na+/K+-ATPase 抑制剂,具有抗肿瘤活性,可与其基 α1、α2 和 α3 结合,Kd 值分别为 42.5、45 和 40 nM。 | |||
T4S0051 |
Coptisine sulfate
|
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Coptisine Sulfate 是一种从黄连中分离到的生物碱,是非竞争性的IDO 抑制剂,Ki=为 5.8 μM,IC50=6.3 μM。 | |||
TN7254 |
(E,E)-Farnesol
(2E,6E)-Farnesol |
Others | Others |
(E,E)-Farnesol ((2E,6E)-Farnesol) 是一种由细菌、原生动物、真菌、植物和动物产生的倍半萜无环醇。(E,E)-Farnesol 可促进血管扩张。 | |||
T4938 |
Potassium 1H-indol-3-yl sulfate
硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate |
AhR; Endogenous Metabolite | Immunology/Inflammation; Metabolism |
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) 是人芳烃受体(AhR)的激动剂。芳烃受体(AhR)最近被发现是免疫炎症条件的病理生理调节剂,Potassium 1H-indol-3-yl sulfate 已被证明是AhR的配体。Potassium 1H-indol-3-yl sulfate 也是膳食蛋白质中色氨酸的代谢物。色氨酸被肠道细菌代谢为吲哚,吲哚被吸收到血液中,然后在肝脏中进一步代谢为硫酸吲哚,通常通过尿液排出体外。在肾功能受损的慢性肾病患者中,Potassium 1H-indol-3-yl sulfate 可作为尿毒症毒素在血清中积累,诱导氧化应激并加速疾病进展。250 μM Potassium 1H-indol-3-yl sulfate 可诱导NF-Κb活化,促进大鼠近端小管细胞TGF-β1和Smad3的表达,与促纤维化活性相关。 | |||
T6512 |
G-418 disulfate
Geneticin,G418 Sulfate,Antibiotic G-418 sulfate,遗传霉素,Geneticin sulfate |
Antibacterial; Antibiotic | Microbiology/Virology |
G-418 disulfate (Geneticin sulfate) 属于氨基糖苷类抗生素,是一种蛋白质合成的抑制剂,具有真核细胞选择性。G-418 disulfate 通过抑制肽链的延伸来阻断多肽合成。 | |||
T2980 |
Chondroitin sulfate
Chonsurid,Chondroitin polysulfate,硫酸软骨素 |
MMP; Others; Endogenous Metabolite; NO Synthase | Immunology/Inflammation; Metabolism; Others; Proteases/Proteasome |
Chondroitin sulfate (Chonsurid) 是一种糖胺聚糖,被广泛用于骨关节炎的研究。它能够减少炎症介质和凋亡过程,并能够减少炎性细胞因子,iNOS 和MMPs 产生。 | |||
T1441 |
Capreomycin sulfate
Capastat sulfate,硫酸卷曲霉素 |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Capreomycin sulfate (Capastat sulfate) 是一种多肽类抗生素,与其它抗生素结合用于MDR-肺结核。 | |||
T2792 |
Glucosamine sulfate
硫酸葡萄糖胺,硫酸氨基葡萄糖,D-Glucosamine sulphate,D-Glucosaminesulfate |
MMP; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite; Autophagy | Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome |
Glucosamine sulfate (D-Glucosaminesulfate) 是软骨基质和滑液中糖胺聚糖的天然成分,常用作骨关节炎的治疗方法。它也是一种氨基糖,是糖基化蛋白和脂质生化合成的突出前体,用作膳食补充剂。 | |||
T4A2462 |
Telocinobufagin
Telobufotoxin,远华蟾蜍精,Telocinobufogenin |
Others | Others |
Telocinobufagin (Telobufotoxin) 是一种从蟾酥中分离提取获得的组份。 | |||
T5A2455 |
Arenobufagin
沙蟾毒精,沙蟾毒经 |
Others | Others |
Arenobufagin 是一种蟾蜍甾烯,从蟾蜍毒液中提取得到,具有抗癌活性。 | |||
TQ0065 |
Pseudobufarenogin
伪异沙蟾毒精,ψ-Bufarenogin |
Others | Others |
Pseudobufarenogin (ψ-Bufarenogin) 是一种蟾蜍毒素提取物,活性背景未知。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02544 |
FANCA Protein, Human, Recombinant (His)
FA-H,FA1,FAA,FAH,FA<... |
Human | Baculovirus Insect Cells |
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IκB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2. | |||
TMPK-00942 |
DLK1 Protein, Mouse, Recombinant (His)
DLK1,DLK,pG2,secredeltin,ZOG,Pref1,DLK-1,FA1 |
Mouse | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q09163-1. | |||
TMPK-00922 |
DLK1 Protein, Human, Recombinant (aa 24-303, His)
FA1,Pref1,DLK1,pG2,DLK,secredeltin,ZOG,DLK-1 |
Human | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (aa 24-303, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is P8037... | |||
TMPK-00921 |
DLK1 Protein, Human, Recombinant (hFc)
DLK1,FA1,pG2,ZOG,secredeltin,DLK,Pref1,DLK-1 |
Human | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 56.58 kDa and the accession number is P80370-1. | |||
TMPK-01274 |
DLK1 Protein, Cynomolgus, Recombinant (His)
FA1,DLK-1,secredeltin,DLK1,ZOG,DLK,Pref1,pG2 |
Cynomolgus | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.26 kDa and the accession number is A0A2K5TMQ6... | |||
TMPY-01101 |
Coagulation factor X/F10 Protein, Human, Recombinant (His)
FXA,FX,coagulation factor X,coagulation fa... |
Human | Baculovirus Insect Cells |
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema... | |||
TMPY-04180 |
PfLDH Protein, P. falciparum, Recombinant (His)
PfLDH,L-lactate dehydrogenase |
P. falciparum | E. coli |
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy. | |||
TMPY-02530 |
Tissue Factor Protein, Human, Recombinant (His)
CD142,coagulation factor III (thromboplastin, tissu... |
Human | HEK293 Cells |
Tissue Factor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P13726. | |||
TMPY-01075 |
Von Willebrand Factor/vWF Protein, Human, Recombinant (His)
von Willebrand factor,VWD,F8VWF |
Human | CHO Cells |
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thr... | |||
TMPY-03221 |
Intrinsic Factor Protein, Human, Recombinant (His)
IF,IFMH,gastric intrinsic factor (vitamin B synthes... |
Human | HEK293 Cells |
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to... | |||
TMPY-04921 |
Complement factor B/CFB Protein, Human, Recombinant (His)
ARMD14,GBG,AHUS4,PBF2,complement factor B,FBI12,BF,... |
Human | HEK293 Cells |
Complement factor B/CFB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and the accession number is AAH04143.1. | |||
TMPY-04922 |
FAP Protein, Human, Recombinant (His), Biotinylated
DPPIV,Fibroblast Activation Protein alpha,DPPIVA,SIMP,Fibrob... |
Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-01104 |
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
coagulation factor 11,coagulation factor X... |
Human | HEK293 Cells |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ... | |||
TMPY-02185 |
Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)
Coagulation factor 13,coagulation factor X... |
Human | HEK293 Cells |
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have en... | |||
TMPY-00828 |
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
MPS2,IDS,SIDS,iduronate 2-sulfatase |
Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an... | |||
TMPY-03956 |
Fas Ligand Protein, Human, Recombinant (His)
TNLG1A,FASL,FASLG,CD178,CD95-L,APT1LG1,APT... |
Human | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei... | |||
TMPY-02154 |
FAP Protein, Human, Recombinant (His)
fibroblast activation protein, alpha,Fibroblast Activation P... |
Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-05094 |
Tissue Factor Protein, Cynomolgus, Recombinant (His)
coagulation factor III (thromboplastin, tissue ... |
Cynomolgus | HEK293 Cells |
Tissue Factor Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is XP_005542723.1. | |||
TMPY-04962 |
FAP Protein, Cynomolgus, Recombinant (His)
fibroblast activation protein, α,fibroblast activation prote... |
Cynomolgus | HEK293 Cells |
FAP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is A0A2K5VGF4. | |||
TMPY-02215 |
Coagulation factor IX/F9 Protein, Human, Recombinant (His)
FIX,PTC,Coagulation factor 9,coagulation fa |
Human | HEK293 Cells |
Coagulation factor IX/F9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is AAB59620.1. | |||
TMPY-02051 |
FABP2 Protein, Human, Recombinant (His)
MGC133132,fatty acid binding protein 2,FAB... |
Human | E. coli |
Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP family proteins could be used as tissue specific injury marker based on the following characteristics of FABP. The intestinal fatty acid binding protein (I-FABP), or fatty acid-binding protein 2 (FABP2), an intracellular protein expressed only in the intestine, involved in the a... | |||
TMPY-06714 |
Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)
coagulation factor IX |
Cynomolgus | HEK293 Cells |
Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.17 kDa and the accession number is A0A8J8XCV8. | |||
TMPH-00455 |
OBP28 Protein, Culex quinquefasciatus, Recombinant (His)
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Culex quinquefasciatus | P. pastoris (Yeast) |
N/A. OBP28 Protein, Culex quinquefasciatus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is B0XC79. | |||
TMPY-00054 |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc)
Macaca fascicularis Cytωlovirus (CyCMV) (strain OT-... |
CyCMV | HEK293 Cells |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 102.5 kDa and the accession number is E7DB34. | |||
TMPY-04996 |
Coagulation Factor II Protein, Rat, Recombinant (His)
coagulation factor II (thrombin) |
Rat | HEK293 Cells |
Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.5 kDa and the accession number is A6HND0. | |||
TMPH-02650 |
FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)
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Mouse | E. coli |
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. | |||
TMPH-01108 |
Factor VII Protein, Human, Recombinant (His & SUMO)
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Human | E. coli |
Factor VII Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-04181 |
pfHPRT Protein, P. falciparum, Recombinant (His)
pfHPRT |
P. falciparum | E. coli |
pfHPRT Protein, P. falciparum, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q76NM3. | |||
TMPK-00993 |
Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)
Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Coagulation... |
Canine | HEK293 Cells |
Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer. | |||
TMPH-03611 |
Sso7d Protein, Sulfolobus solfataricus, Recombinant (His & SUMO)
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Sulfolobus solfataricus | E. coli |
Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature. Stimulates the Holliday junction cleavage activity of Hjc. Sso7d Protein, Sulfolobus solfataricus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 23.1 kDa and the accession number is P39476. | |||
TMPH-03618 |
Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc)
FC,Limulus factor C,Clotting factor C |
Tachypleus tridentatus | E. coli |
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of clotting factor B. Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.8 kDa and the accession number is P28175. | |||
TMPH-00433 |
Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc)
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Coturnix coturnix japonica | E. coli |
Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor. Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) is expr... | |||
TMPJ-00785 |
FABP3 Protein, Human, Recombinant (His)
H-FABP,FABP11,Fatty Acid-Binding ... |
Human | E. coli |
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to p... | |||
TMPY-03151 |
FAM3D Protein, Mouse, Recombinant (His)
FAM3D,family with sequence similarity 3 me... |
Mouse | HEK293 Cells |
FAM3D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.5 kDa and the accession number is P97805. | |||
TMPY-03797 |
Neurofascin Protein, Human, Recombinant (His)
neurofascin,NF,NRCAML |
Human | HEK293 Cells |
Neurofascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.4 kDa and the accession number is O94856-12. | |||
TMPY-00821 |
HGFA Protein (pro form), Human, Recombinant (His)
MGC138397,HGFA,RP11-529E1.2,肝细胞生长因子,MGC138395 |
Human | HEK293 Cells |
HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is clea... | |||
TMPY-00346 |
DEFA3 Protein, Human, Recombinant (hFc)
Defensin α3/DEFA3,defensin alpha 3,HP-3,HNP-3,DEF3,... |
Human | HEK293 Cells |
DEFA3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.8 kDa and the accession number is P59666. | |||
TMPY-02873 |
Legumain Protein, Sus scrofa (Pig), Recombinant (His)
legumain |
Sus scrofa (Pig) | HEK293 Cells |
Legumain Protein, Sus scrofa (Pig), Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.7 kDa and the accession number is A0A287AW67. | |||
TMPH-01930 |
CBFA2T1 Protein, Human, Recombinant (His & Myc)
CDR,ETO,AML1T1,Eight twenty one protein,RUNX1T1,Cyclin-D-rel... |
Human | E. coli |
CBFA2T1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-01935 |
FAM167A Protein, Human, Recombinant (His & Myc)
|
Human | HEK293 Cells |
FAM167A Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-03140 |
Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His)
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Plasmodium falciparum | E. coli |
During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.0 k... | |||
TMPY-03941 |
FAM3D Protein, Mouse, Recombinant (hFc)
FAM3D,family with sequence similarity 3 me... |
Mouse | HEK293 Cells |
FAM3D Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P97805. | |||
TMPY-04587 |
Fas Ligand Protein, Mouse, Recombinant (His)
CD178,Apt1lg1,Fasl,Cd95l,Faslg,Tnfsf6,gld,... |
Mouse | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei... | |||
TMPH-02674 |
GFAP Protein, Mouse, Recombinant
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Mouse | Baculovirus Insect Cells |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPH-01772 |
DEFA1 Protein, Human, Recombinant (GST)
MRS,HP1,HP-1,DEFA1,DEF1,Defensin, alpha 1,Neutrophi... |
Human | E. coli |
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665. | |||
TMPH-03142 |
Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc)
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Plasmodium falciparum | E. coli |
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. T... | |||
TMPY-04838 |
PDGFA Protein, Mouse, Recombinant (His)
platelet-derived growth factor α polypeptide,血小板源生长... |
Mouse | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDG... | |||
TMPH-03217 |
VEGFA Protein, Rabbit, Recombinant (His)
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Rabbit | P. pastoris (Yeast) |
VEGFA Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 51.7 kDa and the accession number is XP_002714743.1. | |||
TMPH-00534 |
Gelatinase Protein, Enterococcus faecalis, Recombinant (His & SUMO)
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Enterococcus faecalis | E. coli |
Metalloprotease capable of the hydrolysis of insoluble hydrophobic substrates. Hydrolyzes azocoll and gelatin and, at a lower rate, soluble and insoluble collagens. Does not cleave short synthetic peptides. Preferentially hydrolyzes the 24-Phe-|-Phe-25 bond in the insulin B-chain, followed by the 5-His-|-Leu-6 bond. Inactivates endothelin-1, primarily by cleavage of the 5-Ser-|-Leu-6 and 16-His-|-Leu-17 bonds. Hydrolyzes the alpha chain of C3 to generate a C3b-like protein. Inhibits complement-m... | |||
TMPH-03706 |
LEB6 Protein, Vicia faba, Recombinant (His)
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Vicia faba | P. pastoris (Yeast) |
This protein found in the seeds of many leguminous and non-leguminous plants is the source of sulfur-containing amino acids in seed meals. LEB6 Protein, Vicia faba, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.0 kDa and the accession number is P16079. | |||
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