307
53
1
1780
Cat. No. | Product Name | ||
---|---|---|---|
L7800 | 高溶解性片段库 | 2728 compounds | |
2728 种片段分子合集,数量适中,是 FBDD 方法新药筛选的有力工具。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27066 |
Prostaglandin G/H synthase 1 inhibitor
CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide |
Others | Others |
Prostaglandin G/H synthase 1 inhibitor (CP 74006) 是一种选择性D5D 抑制剂,IC(50)值为20nM。 | |||
T12155 |
Y1 receptor antagonist 1
H 409-22 isomer |
Others | Others |
Y1 receptor antagonist 1 is an antagonist of neuropeptide Y1 receptor. | |||
TP1750L |
H-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate(26001-32-1 free base) |
Angiotensin-converting Enzyme (ACE) | Metabolism |
H-Ile-Pro-Pro-OH acetate 是一种血管紧张素转换酶抑制剂,为乳源三肽。 | |||
T10499 |
H3 receptor-MO-1
|
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
H3 receptor-MO-1 是一种有效的组胺 H3 受体 (histamine H3 receptor) 调节剂,可用于研究神经分裂和认知障碍。 | |||
T5829 |
H4 Receptor antagonist 1
|
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
H4 Receptor antagonist 1 是选择性组胺 H4受体反向激动剂,其IC50值为19 nM。 | |||
T29301 |
1-H-Perflurodecane
10H-heneicosafluoro-decane,heneicosafluoro-n-decane |
||
1-H-Perflurodecane is a biochemical. | |||
T60109 |
Protein kinase inhibitor H-7
5-(2-methylpiperazine-1-sulfonyl)isoquinoline,蛋白激酶抑制剂H-7,1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Protein kinase inhibitor H-7 (5-(2-methylpiperazine-1-sulfonyl)isoquinoline) 是有效的蛋白激酶 C (PKC) 和环核苷酸依赖性蛋白激酶抑制剂,抑制 PKC 的 Ki 值为 6 μM。 | |||
T21627 |
Hoechst 33342 trihydrochloride
HOE 33342 trihydrochloride,bisBenzimide H 33342 trihydrochloride,bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride,Hoechst 33342 |
Others; Autophagy | Autophagy; Others |
Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) 是一种可透过膜的蓝色荧光 DNA 染料。 | |||
T79492 |
h-NTPDase8-IN-1
|
Phosphatase | Metabolism |
h-NTPDase8-IN-1 是一种特异性氨磺酰苯甲酰胺类 h-NTPDases8 抑制剂(IC 50 = 0.28 ± 0.07 μM)。h-NTPDase8-IN-1 可用于研究 h -NTPDase 表达异常带来的疾病。 | |||
T38766L |
Histone H3 (1-35) acetate
|
Others | Others |
Histone H3 (1-35) acetate 是组蛋白 H3 的 35 个残基肽。组蛋白 H3 是一种重要的蛋白质,在基因的动态和长期调控中发挥作用。 | |||
T9010 |
IMM-H007
|
Others; AMPK | Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling |
IMM-H007 是一种新型降脂剂,可增加 abca1 蛋白的表达。 | |||
T19455 |
N-ε-propargyloxycarbonyl-L-lysine hydrochloride
N6-((Prop-2-yn-1-yloxy)carbonyl)-L-lysine hydrochloride,N-Ε-炔丙氧基羰基-L-赖氨酸盐酸盐,H-L-Lys(Poc)-OH (hydrochloride) |
Others | Others |
N-ε-propargyloxycarbonyl-L-lysine hydrochloride (N6-((Prop-2-yn-1-yloxy)carbonyl)-L-lysine hydrochloride) 是一种基于赖氨酸的非天然氨基酸 (UAA)。它普遍用于多种生物体中荧光探针的生物偶联。 | |||
T8958 |
PU-H54
|
GPR | Endocrinology/Hormones; GPCR/G Protein |
PU-H54 是一种基于嘌呤的 Grp94 抑制剂。它是一种基于 Grp94 选择性间苯二酚的抑制剂,通过探测 Grp94 中 S2 亚袋的专有结合区而分离。 | |||
T7501 |
Iso-H7 dihydrochloride
1-(5-硫代异喹啉)-3-甲基哌嗪二盐酸盐 |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
与 H-7 相比,Iso-H7 dihydrochloride 是一种较弱的磷酸激酶 C 抑制剂。 | |||
T2568L |
Felypressin acetate
2-(L-Phenylalanine)-8-L-lysinevasopressin,醋酸苯赖加压素,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2 |
Vasopressin Receptor | GPCR/G Protein |
Felypressin acetate (PLV-2) 是加压素 1 的激动剂,作用于所有精氨酸加压素受体 1AS。 Felypressin acetate 可用于牙科手术。 | |||
T11532 |
H4R antagonist 1
|
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
H4R antagonist 1 is a highly selective histamine H4 receptor (H4R) antagonist (IC50: 27 nM). H4R antagonist 1 does not show any noticeable binding affinity to other subtypes of histamine receptors, H1R, H2R, and H3R. | |||
T26334 |
WWamide-1
H-Trp-lys-glu-met-ser-val-trp-NH2 |
||
WWamide-1 is a neuromodulatory peptide isolated from the ganglia of Afrian giant snail, Achatina fulica. | |||
T37328 |
Prostaglandin H1
Prostaglandin H1 |
||
Prostaglandin H1 是 DGLA 的环氧化酶代谢物,也是一种 CRTh2 激动剂以及 1 系列抗炎前列腺素的前体物质。Prostaglandin H1 可用于炎症的研究。 | |||
T10911 |
H3 receptor antagonist 1
|
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist. | |||
T11531 |
H3R-IN-1 Hydrochloride
|
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
H3R-IN-1 Hydrochloride 是一种有效的组胺H3受体 (H3R) 的反向激动剂。 | |||
T37720 |
Difluorinated H2S Fluorescent Probe 1
|
||
Difluorinated H2S probe 1 is a fluorescent probe for hydrogen sulfide (H2S).1It selectively fluoresces in the presence of H2S over Zn2+, Fe3+, S2O32-, ClO-, SO32-, H2O2, NO2-, cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) when used at a concentration of 1 μM. Difluorinated H2S probe 1 displays excitation/emission maxima of 365/450 nm, respectively. 1.Zhang, J., Gao, Y., Kang, X., et al.o,o-Difluorination of aromatic azide yields a fast-response fluorescent probe for H2S detection and... | |||
T40993 |
Histone H3 (1-21)
Histone H3 (1-21) |
||
Histone H3 (1-21) is a truncated form of the Histone H3 protein consisting of amino acids 1 to 21. It serves as a common substrate for methyltransferase assays targeting Histone 3 at lysine 4 and lysine 9, as well as for acetyltransferase assays targeting Histone 3 at lysine 9 and lysine 14. | |||
T38766 |
Histone H3 (1-35)
Histone H3 (1-35) |
||
Histone H3 (1-35) is a 35-residue peptide derived from histone H3, which is a key member of the five main histones participating in the formation of chromatin within eukaryotic cells. | |||
T38634 |
Histamine H4 receptor antagonist-1
Histamine H4 receptor antagonist-1 |
||
Histamine H4 receptor antagonist-1 is a potent antagonist of the histamine H4 receptor. | |||
T38784 |
Histone H3 (1-25), amide
Histone H3 (1-25), amide |
||
Histone H3 (1-25), amide is a N-terminal peptide fragment of histone H3 that serves as a substrate for histone methyltransferases (HMTs). It can be utilized to identify the substrate for HMTs. Compared to histone H3 (15-39) and full-length histone H3, Histone H3 (1-25), amide proves to be more efficient as a substrate for HMT G9a. | |||
T81620 |
OfChi-h-IN-1
|
||
OfChi-h-IN-1,一种高效的OfChi-h抑制剂,Ki为0.33 μM。该化合物能显著抑制幼虫生长发育,并表现出比Hexaflumuron更强的杀虫活性,是昆虫生长调节剂的新型候选物。 | |||
T79491 |
h-NTPDase-IN-1
|
Phosphatase | Metabolism |
h-NTPDase-IN-1 (Compound 3i) 是一种针对 h-NTPDase 的抑制剂,对 h-NTPDase1 和 h-NTPDase3 的抑制作用表现在 IC50 值分别为 2.88 μM 和 0.72 μM。该化合物在血栓、炎症、糖尿病及癌症研究领域有潜在应用。 | |||
T41019 |
Histone H1-derived Peptide
Histone H1-derived Peptide |
||
Histone H1-derived peptide is a phosphopeptide with peptide substrates that consist of a sequence aligned with the optimal recognition motif for cyclin-dependent kinases (CDKs). | |||
T36095 |
Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt)
Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt) |
||
Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt) 可用于生命科学领域的相关研究,其产品编号为 T36095。 | |||
T2568 |
Felypressin
Octapressin,Felypressin Acetate,PLV-2,H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,苯赖加压素 |
Vasopressin Receptor | GPCR/G Protein |
Felypressin (Octapressin) 是一种加压素 1 激动剂,也是血管收缩剂,可用于牙科手术中。 | |||
T65771 |
1,7'-Dimethyl-2'-propyl-1H,1'H-2,5'-bibenzo[d]imidazole
|
||
1,7'-Dimethyl-2'-propyl-1H,1'H-2,5'-bibenzo[d]imidazole 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65771,CAS号为 152628-02-9。 | |||
T67324 | (1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide | ||
(1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67324,CAS号为 900160-98-7。 | |||
T12219 |
NHE3-IN-1
|
Sodium Channel | Membrane transporter/Ion channel |
NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。 | |||
T77640 |
Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate 对 NAD(P)H:醌氧化还原酶 1 具有抑制作用。 | |||
T40840 |
H-Tyr-Ala-OH
H-Tyr-Ala-OH,Tyrosylalanine |
Others | Others |
H-Tyr-Ala-OH (Tyrosylalanine) 是一种L-酪氨酸和L-丙氨酸组成的二肽。 | |||
T38344 |
Lalistat 1
ZINC795230 |
Antibacterial | Microbiology/Virology |
Lalistat 1是溶酶体酸性脂肪酶(LAL)抑制剂(IC50 = 68 nM)和流感病毒IgA1蛋白酶的抑制剂。Lalistat 1可用于有关尼曼-皮克C 型疾病的研究。 | |||
T1876 |
Kobe0065
|
Apoptosis; Raf; Ras | Apoptosis; GPCR/G Protein; MAPK |
Kobe0065 是一种新型 Ras-Raf 相互作用抑制剂,可完全抑制 H-Ras·GTP 与 c-Raf-1 RBD 的结合,Ki 值为 46±13 μM。 | |||
T25984 |
(±)-Prenalterol
H80/62,H-80/62,H 80/62 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
(±)-Prenalterol (H 80/62) 是一种新的心脏选择性正性肌力化合物,是β-2-和β-1-肾上腺素受体的激动剂,可用于研究慢性充血性心力衰竭。 | |||
T21493 |
Cyclosporin H
|
Others | Others |
Cyclosporin H 是一种 FPR-1(甲酰肽受体 1) 的选择性强效抑制剂。它缺乏 Cyclosporin A 具有的免疫抑制活性。它是一种病毒转导增强剂,可使人脐带血来源的造血干细胞和祖细胞中慢病毒转导增强 10 倍。它与雷帕霉素或前列腺素 E2 联合使用时表现出累加效应。 | |||
T19561 |
Simetryn
|
Others | Others |
Simetryn 是一种稻田除草剂,可作为一种化学应激源,延缓蝌蚪的生长和发育,而不会破坏甲状腺功能,即使在 96 小时 LC50 值的 1/100 时也是如此。 | |||
T1540 |
Doxepin hydrochloride
Toruan,Doxepin HCl,Aponal,Novoxapin,盐酸多塞平 |
P450; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Doxepin hydrochloride (Aponal) 是一种可口服的三环抗抑郁剂,是选择性组胺受体 H1拮抗剂。它也是 CYP450抑制剂,抑制 CYP450 2C19和 CYP450 1A2。 | |||
T4172 |
Methoxy-PMS
1-Methoxyphenazine methosulfate,1-Methoxy PMS |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Methoxy-PMS (1-Methoxyphenazine methosulfate) 是一个稳定的电子传递中介,是一种活性氧生成的诱导剂。 | |||
T38050 |
CP-609754
|
Transferase | Metabolism |
CP-609754 是高效的、可逆的法尼基转移酶抑制剂,对重组人 H-Ras 和重组 K-Ras 法尼基化的 IC50分别为 0.57 ng/mL 和 46 ng/mL。CP-609754有潜在的抗癌作用。 | |||
T9381 |
Thalidomide 5-fluoride
2-(2,6-二氧代 - 哌啶-3-基)-5-氟 - 异吲哚-1,3-二酮,H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro- |
Ligand for E3 Ligase | PROTAC |
Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) 是一种基于沙利度胺的 Cereblon 配体,通过 linker 与 IRAK4 蛋白配体结合形成 PROTACIRAK4 degrader-1。 | |||
T2043 |
Mutant IDH1-IN-1
IDH1-IN-1 |
Dehydrogenase; Isocitrate Dehydrogenase (IDH) | Metabolism |
Mutant IDH1-IN-1 是 IDH1突变体的选择性抑制剂,能够作用于突变体 IDH1 R132C/R132C (IC50:4 nM) ,IDH1 R132H/R132H (IC50:42 nM) ,IDH1 R132H/WT (IC50:80 nM) 和野生型 IDH1 (IC50:143 nM)。 | |||
T36493 |
CMLD-2
|
Apoptosis; HuR | Apoptosis; Chromatin/Epigenetic |
CMLD-2是一种 HuR-ARE 相互作用的抑制剂(Ki:350 nM),能竞争性地结合 HuR 蛋白并破坏其与富含腺嘌呤元素(ARE)的 mRNA 目标的相互作用。CMLD-2诱导细胞凋亡并通过 MAD2下调表现出抗肿瘤作用。CMLD-2 (1-75 μM ; 24-72 h) 对甲状腺癌细胞的活力具有抑制作用.CMLD-2 (20-30 μM ; 24-48 h) 激活 Caspases 并诱导H1299和A549细胞凋亡.CMLD-2 (30 μM ; 24-48 h) 诱导H1299和A549细胞的G1细胞周期停止和线粒体扰动。 CMLD-2(30μM;24-48小时)减少H1299细胞中HuR 和HuR 调节的mRNAs 和蛋白质的表达.CMLD-2(35μM;72小时)降低SW1736、8505C、BCPAP 和K1细胞的定向迁移能力。CMLD-2诱导SW1736、8505C、BCPAP 和K1细胞中的MAD2 mRNA 水平强烈下降。 | |||
T16342 |
KL1333
NQO1 activator 1 |
NADPH; Mitochondrial Metabolism | Metabolism |
KL1333 (NQO1 activator 1) 是口服NAD+调节剂,与 NAD(P)H: 醌氧化还原酶 1 作为底物反应。它改善线粒体脑肌病、乳酸酸中毒和中风样发作成纤维细胞的能量代谢和线粒体功能障碍。它对顺铂诱导的小鼠耳蜗培养耳毒性的保护作用。 | |||
T5319 |
Rimeporide
EMD-87580 |
Sodium Channel | Membrane transporter/Ion channel |
Rimeporide (EMD-87580) 是有效的 Na+/H+交换泵 (NHE-1) 选择性抑制剂。 | |||
T63140 |
LSD1-IN-20
|
Histone Demethylase | Chromatin/Epigenetic |
LSD1-IN-20 是一种有效的 LSD1/G9a 双重抑制剂,其 Ki 值分别为 0.44 和 0.68 μM。LSD1-IN-20 在体外实验中对 THP-1 白血病细胞和 MDA-MB-231 乳腺癌细胞显示出抗增殖活性,72 h 时 IC50 分别为 0.51 和 1.60 μM。 | |||
T5333 |
Rimeporide hydrochloride
盐酸Rimeporide,EMD-87580 hydrochloride |
Sodium Channel | Membrane transporter/Ion channel |
Rimeporide hydrochloride (EMD-87580 hydrochloride) 是一种有效的 Na+/H+交换泵(NHE-1) 选择性抑制剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1494 |
Cimicifugoside H-1
黑升麻苷H-1 |
Others | Others |
Cimicifugoside H1 是C. foetidaL.C 提取物的主要成分,是一种环甾烷醇木糖苷。它对骨吸收及卵巢切除术引起的骨质流失具有抑制作用。 | |||
T2715 |
Tubeimoside I
土贝母苷甲I,Tubeimoside-1,Lobatoside-H |
Apoptosis; Others | Apoptosis; Others |
Tubeimoside I (Tubeimoside-1) 是中药土贝母提取物,是一种抗肿瘤剂。 | |||
TN7160 |
3,3'-Bi[1H-indole]
3,3'-Biindole,1H,1'H-3,3'-双吲哚,3-(1H-indol-3-yl)-1H-indole,1H,1'H-3,3'-biindole |
Others | Others |
3,3'-Bi[1H-indole] (3,3'-Biindole)是一种海洋来源的天然产物,存在于Nocardiopsis sp.。 | |||
TN2119 |
Pulsatilla saponin H
白头翁属皂苷H,白头翁皂苷 H,3-O-Β-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 常春藤配基- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷 |
Others | Others |
Pulsatilla saponin H 是一种从 Pulsatilla koreana 的根中分离出来的天然产物。 | |||
T1686 |
Hematoxylin
苏木精,Hydroxybrazilin,Natural Black 1,Haematoxylin |
Beta Amyloid; Others | Neuroscience; Others |
Hematoxylin (Natural Black 1) 是一种天然存在的类黄酮化合物,衍生自木柴树Haematoxylon campechianum。它是一种组织学上的核染色剂,也是一种有效的Aβ42原纤维形成的抑制剂,IC50=1.6 µM。 | |||
T1311 |
4-aminobenzoic acid
PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid,对氨基苯甲酸 |
Endogenous Metabolite | Metabolism |
4-aminobenzoic acid (para-Aminobenzoic acid) 是一种具有紫外线吸收和抗纤维化特性的有机酸。当暴露在光线下时,4-aminobenzoic acid 吸收紫外线并通过光化学反应释放多余的能量,这可能会对DNA造成损害。4-aminobenzoic acid 还可以增加组织水平的摄氧量,并可能增强单胺氧化酶(MAO)活性以促进血清素的降解,过量可能导致纤维化变化。 | |||
T5368 |
Eicosapentaenoic Acid
|
Histone Demethylase; Others; Endogenous Metabolite | Chromatin/Epigenetic; Metabolism; Others |
Eicosapentaenoic Acid 是一种 ω-3 脂肪酸。 | |||
T40490 |
Phenylalanylalanine
H-Phe-Ala-OH,苯并氨酰丙氨酸 |
Others | Others |
Phenylalanylalanine(H-Phe-Ala-OH)是由苯丙氨酸和丙氨酸融合形成的二肽。它在蛋白质的不完全消化或分解过程中形成[1]。 | |||
TN5503 |
Linaroside
|
Antibacterial | Microbiology/Virology |
Linaroside 在 6.25 microg mL(-1) 浓度下对结核分枝杆菌、菌株 H(37)Rv 的抗分枝杆菌活性表现出 30%的抑制作用。 | |||
TN1664 |
Ganoderic acid H
|
NF-κB; DNA/RNA Synthesis; CDK | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; NF-κB |
Ganoderic acid H 是一种羊毛脂烷型三萜,提取自灵芝中。它能够抑制转录因子AP-1 和 NF-kappaB 信号,并抑制乳腺癌细胞细胞的生长和入侵。 | |||
T5S0620 |
3-Dehydrotrametenolic acid
Dehydrotrametenolic acid,松苓新酸,3-氢化去氢松苓酸 |
Apoptosis; Others; Dehydrogenase | Apoptosis; Metabolism; Others |
3-Dehydrotrametenolic acid 是从茯苓菌核分离的一种乳酸脱氢酶抑制剂,可诱导细胞凋亡,具有抗癌活性。它促进体外脂肪细胞分化,在体内起胰岛素增敏剂的作用。 | |||
T5799 |
Arecaidine hydrochloride
|
Others | Others |
Arecaidine hydrochloride 是一种具有高效 GABA 吸收抑制功能的吡啶生物碱。它是 H+偶联的氨基酸转运蛋白 1 (PAT1,SLC36A1) 的底物,能够竞争性抑制 L-脯氨酸的摄取。 | |||
T3S2344 |
β,β-Dimethylacrylshikonin
β,β-二甲基丙烯酰紫草素,Dimethylacrylshikonin,β, β-Dimethylacrylshikonin |
ERK; HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; MAPK; Metabolism |
β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) 是一种萘醌衍生物,从 Arnebia nobilis 中提取得到。它利用 PI3K 通路诱导 eNOS、VEGF 和 HIF-1α 的表达,促进血管生成,具有抗肿瘤活性。 | |||
T2S1865 |
Octyl gallate
Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯 |
Antioxidant; Influenza Virus; Reactive Oxygen Species; Antibacterial; Antifungal; HSV | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction |
Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用,有选择性和敏感性的荧光特性,广泛用作食品添加剂。它对 HSV-1,水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。 | |||
TN1103 |
Diphyllin
山荷叶素,二叶草素 |
ATPase; Proton pump; Influenza Virus; HIV Protease | Membrane transporter/Ion channel; Microbiology/Virology; Proteases/Proteasome |
Diphyllin 是一种从Justicia procumbens 中分离的芳基萘木脂素,是HIV-1的有效抑制剂,IC50 为 0.38 μM。它是V-ATPase 抑制剂,IC50值为 17 nM,可抑制人破骨细胞中的溶酶体酸化。它抑制NO 产生,IC50值为 50 μM ,具有抗癌和抗炎活性。 | |||
T2S0843 |
Negletein
黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether |
IL Receptor; TNF; NOS; Interleukin | Apoptosis; Immunology/Inflammation |
Negletein (7-O-Methylbaicalein) 一种神经保护剂,可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性,其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。 | |||
T0809 |
Dicoumarol
Dicumarol,双羟香豆素,双香豆素 |
Dehydrogenase; NADPH; PDK | Metabolism; PI3K/Akt/mTOR signaling |
Dicoumarol (Dicumarol) 是一种 NAD(P)H: 醌氧化还原酶 1 和PDK1的抑制剂,它们的IC50值分别为 0.37 和 19.42 μM。 | |||
T36914 |
2-Hydroxyanthraquinone
|
Others | Others |
2-Hydroxyanthraquinone 是一种天然产物,显示出抗肿瘤和免疫抑制活性。 | |||
T6S1684 |
8-Gingerol
|
Antioxidant; Antibacterial; TRP/TRPV Channel | Membrane transporter/Ion channel; Microbiology/Virology; oxidation-reduction |
8-Gingerol 分离自姜的根状茎,是口服有效的 TRPV1激活剂,EC50值为5.0 µM。8-Gingerol 抑制 COX-2,还能抑制体外 H. pylori 的生长。 | |||
T81419 |
Poricoic acid H
|
||
Poricoic acid H为三萜类化合物,具备独特的化学结构和生物活性。 | |||
T81545 |
Parisyunnanoside H
|
||
Parisyunnanoside H,一种甾体皂苷,可从Paris polyphylla Smith var. yunnanensis分离提取。 | |||
T6535 |
Histamine Phosphate
组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Histamine Phosphate (Histamine acid phosphate) 是组胺受体的强激活剂和血管扩张神经剂,可激活一氧化氮合成酶。 | |||
T82563 |
Dichotomine H
|
||
Dichotomine H,一种从银柴胡 (Stellaria dichotoma L.) 提取的 p-咔啉生物碱,具有显著的抗过敏活性。 | |||
T81965 |
Laccaic acid C
|
||
Laccaic acid C,以8.1 μM的IC50有效抑制RNase H并能阻止病毒在细胞内的增殖。 | |||
T80013 |
Arecaidine hydrobromide
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Arecaidine hydrobromide,一种吡啶生物碱,有效抑制GABA吸收。作为H+偶联的氨基酸转运蛋白1(PAT1,SLC36A1)的底物,它竞争性地抑制L-脯氨酸的摄取。 | |||
TN3572 |
Calyxin H
|
HSP | Cytoskeletal Signaling; Metabolism |
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer. | |||
T80004 |
Tetrahydrorhombifoline
|
||
TetraHydrorhombifoline为Genista vuralii A. Duran & H. Dural 地上部分所含喹啉西啶类生物碱。G. vuralii 生物碱提取物显示出抗菌与抗真菌作用。 | |||
T79954 |
Kadsulignan H
|
NO Synthase | Immunology/Inflammation |
Kadsulignan H (compound 13),作为一种木脂素类化合物,展现了对 NO 产生的显著抑制作用。在 BV-2 细胞中,该化合物通过 IC50 值为 14.1 μM 来表征其对 NO 生成的抑制活性。 | |||
T80939 |
Triptoquinone H
|
||
Triptoquinone H是从雷公藤中提取的天然产物,显示出显著的细胞毒性、免疫调节作用和抗炎活性,适用于癌症和炎症疾病的研究。 | |||
TN4778 |
Physalin H
|
gp120/CD4; Antifection; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology |
Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) value of 3.74±0.02. Physalin H shows immunosuppressive effects on T cells both | |||
T80003 |
Wulfenioidin H
|
||
Wulfenioidin H (Compound 5) 是二萜类化合物,对抗寨卡病毒(ZIKV)活性显著,其EC50为 8.50 μM。该化合物能够通过抑制ZIKV包膜(E)蛋白表达来干预病毒复制。 | |||
T72732 |
Massarilactone H
|
||
Massarilactone H 是一种聚酮化合物,是神经氨酸酶抑制剂,IC50值为 8.18 µM。 | |||
T75499 | Maceneolignan H | ||
Maceneolignan H (Compound 8)是一种新的木脂素化合物,从肉豆蔻假种皮中分离而来。它表现为选择性CCR3拮抗剂(EC50=1.4 μM),具有研究过敏性疾病潜力。 | |||
T78465 |
H-γ-Glu-Gln-OH
γ-Glutamylglutamine,γ-Glu-Gln |
||
H-γ-Glu-Gln-OH 是一种水溶性肽类化合物,用于药物结合。该载体特征为高溶解度、药物负载效能、优良生物相容性、低毒性,并能增强抗癌药物对肿瘤的靶向作用及疗效。 | |||
T81770 |
Mollicellin H
|
||
Mollicellin H, 次级代谢物源于真菌C. brasiliense,显示出免疫调节、细胞毒性和抗肿瘤等多种生物活性。它对三种人类癌细胞系——乳腺癌 (Bre04)、肺癌 (Lu04) 和神经瘤 (N04) 的生长抑制半数有效浓度 (GI50s) 分别为5.1 μg/mL、6.5 μg/mL 和2.5 μg/mL。 | |||
T38069 |
Aquastatin A
|
||
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K.... | |||
T72152 |
Eicosapentaenoic Acid sodium
二十碳五烯酸钠盐,Timnodonic acid sodium,EPA sodium |
||
Eicosapentaenoic Acid (EPA) sodium 为口服活性 ω-3 长链多不饱和脂肪酸 (ω-3 LC-PUFAs)。其通过DNA去甲基化,促进肿瘤抑制基因CCAAT/增强子结合蛋白δ (C/EBPδ)的重新表达,并通过H-RAS内含子1 CpG岛的去甲基化,激活U937白血病细胞中RAS/ERK/C/EBPβ途径。此外,该化合物能够促进血管平滑肌细胞松弛和血管舒张。 | |||
T37451 |
Stachybotrysin B
|
||
Stachybotrysin B is a fungal metabolite originally isolated from S. chartarum and has antiviral and anticancer activities.1,2 It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM).1 Stachybotrysin B is cytotoxic to K562, HeLa, and HL-60 cells (IC50s = 21.72, 39.63, and 18.5 μM, respectively).2 |1. Zhao, J., Feng, J., Tan, Z., et al. Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. J. Nat. Prod. 80(6), 1819-1826 (2017).|2. Ma, X.-h., Zhen... | |||
T38330 |
Collinin
|
||
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a... | |||
T36226 |
Beauveriolide I
|
||
Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 μM, as well as inhibits cholesterol synthesis (IC50= 0.78 μM), in primary mouse peritoneal macrophages.1,2Beauveriolide I also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 6 μM).2 1.Namatame, I., Tomoda, H., Si, S., et al.Beauveriolides, specific i... | |||
T38038 |
(-)-Rasfonin
|
||
(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively). References1. Fujimoto, H., Okamoto, Y., Sone, E., et al. Eleven new 2-pyrones from a fungi imperfecti, Trichurus terrophilus, found in a screening study guided by immunomodulatory activity. Chem. Pharm. Bull. (Tokyo) 53(8), 923-929 (2005). | |||
T36337 |
Burnettramic Acid A aglycone
|
||
Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated fromA. burnettiithat has anticancer activity.1It is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 8.4 and >100 μg/ml, respectively). 1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus... | |||
T36448 |
(E)-Ajoene
|
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(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth... | |||
T36227 |
Beauveriolide III
|
||
Beauveriolide III is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 μM, as well as inhibits cholesterol synthesis (IC50= 0.41 μM), in primary mouse peritoneal macrophages.1,2Beauveriolide III also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 5.5 μM).2Beauveriolide III (25 and 50 mg/kg) reduces the size of aortic ... | |||
T37609 |
(rel)-Asperparaline A
|
||
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces... | |||
T35761 |
Carviolin
|
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Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes (IC50s = 4 and 4.5 μg/ml, respectively).1Carviolin is active againstT. b. brucei(MIC = 41.66 μM).2 1.Fujimoto, H., Nakamura, E., Okuyama, E., et al.Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory... | |||
T36438 |
Sporogen-AO 1
|
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Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO 1 is cytotoxic to HeLa, KB, and NCI H187 cancer cells (IC50s = 8.3, 9, and 5.1 μM, respectively).2,5It is active againstC. albicans(MIC = 4 mM).3 1.Tanaka, S., Wada, K., Marumo, S., et al.Structure of sporogen-ao 1, a sporogenic substance of Aspergillus oryzaeTetrahedron Lett.25(... | |||
T36915 |
21-Deoxycortisol
|
||
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies. 1.Fiet, J., Villette, J.-M., Galons, H., et al.The application of a new highly-sensitive... | |||
T36000 |
3-Hydroxyterphenyllin
|
||
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi... | |||
T35752 |
Xanthoquinodin A1
Xanthoquinodin A1 |
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Xanthoquinodin A1 is a fungal metabolite that has been found inHumicolaand has diverse biological activities.1,2It inhibitsE. tenellaschizont formation in BHK-21 cells with a minimum effective concentration (MEC) value of 0.02 μg/ml.1Xanthoquinodin A1 is active againstB. subtilis,M. luteus,S. aureus,A. laidlawii, andB. fragilisin a disc assay when used at a concentration of 1 mg/ml. It is also active againstB. cereus(MIC = 0.44 μM).2Xanthoquinodin A1 is cytotoxic to KB, MCF-7, and NCI H187 cance... | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03407 |
NQO1 Protein, Human, Recombinant (His)
NAD(P)H dehydrogenase, quinone 1,... |
Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex... | |||
TMPY-04949 |
PD-L1 Protein, Human, Recombinant (His), Biotinylated
PDCD1LG1,B7H1,PD-L1<... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-04343 |
PD-L1 Protein, Human, Recombinant (His)
PDL1,B7-H,B7H1,PDCD1... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-05208 |
PD-L1 Protein, Human, Recombinant
CD274 molecule,PDCD1L1,PD-L1,PDL<... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-02473 |
ICOS Protein, Mouse, Recombinant (hFc)
H4,CRP-1,AILIM,Ly115,CCL... |
Mouse | HEK293 Cells |
ICOS Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q9WVS0. | |||
TMPH-00117 |
Ara h 1, clone P17 Protein, Arachis hypogaea, Recombinant (His)
Allergen Ara h I,Ara h 1,Allergen... |
Arachis hypogaea | E. coli |
N/A. Ara h 1, clone P17 Protein, Arachis hypogaea, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 71.7 kDa and the accession number is P43237. | |||
TMPY-04129 |
Complement factor H/CFH Protein, Mouse, Recombinant (His)
Sas-1,Mud-1,NOM,complement factor H |
Mouse | HEK293 Cells |
Complement factor H/CFH Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.8 kDa and the accession number is E9Q8I0. | |||
TMPY-04141 |
Complement factor H/CFH Protein, Mouse, Recombinant (hFc)
complement factor H,Sas1,NOM,Mud-1 |
Mouse | HEK293 Cells |
Complement factor H/CFH Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.1 kDa and the accession number is E9Q8I0. | |||
TMPY-02580 |
Histone H1 Protein, Human, Recombinant (His)
HSP60,HSP65,CPN60,H1 |
Human | E. coli |
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes, all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-termin... | |||
TMPK-00790 |
Complement factor H/CFH Protein, Human, Recombinant (His)
ARMD4,AHUS1,H factor 1,<... |
Human | HEK293 Cells |
Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self)... | |||
TMPJ-00770 |
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
Gzmb,Cytotoxic cell protease 1,Fragmentin-2,CTLA- |
Mouse | HEK293 Cells |
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. | |||
TMPY-06768 |
NR1H4 Protein, Human, Recombinant (His)
FXR,BAR,nuclear receptor subfamily 1, group H |
Human | E. coli |
NR1H4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.83 kDa and the accession number is Q96RI1-1. | |||
TMPY-01826 |
Relaxin 1/RLN1 Protein, Human, Recombinant (His)
RLXH1,H1RLX,relaxin ... |
Human | HEK293 Cells |
Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductive hormone 8 years ago, relaxin has been implicated in a number of pregnancy-related functions involving extracellular matrix (ECM) turnover and collagen degradation. It is now becoming evident that relaxin's ability to reduce matrix synthesis and increase ECM degradation has impo... | |||
TMPY-02220 |
HRAS Protein, Human, Recombinant (His)
HAMSV,Harvey rat sarcoma viral oncogene |
Human | Baculovirus Insect Cells |
HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Defects in HRAS are the cause of faciocutaneoskeletal syndrome (FCSS). FCSS is a rare condition characterized by prenatally increase... | |||
TMPK-00662 |
PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated
PDCD1LG1,B7-H1,B7H |
Cynomolgus,Rhesus | HEK293 Cells |
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His t... | |||
TMPY-00605 |
FABP3 Protein, Mouse, Recombinant
Fabph1,Fabph-1,Fabph... |
Mouse | E. coli |
FABP3 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.8 kDa and the accession number is P11404. | |||
TMPY-03174 |
CFHR1 Protein, Human, Recombinant (His)
CFHL1,H36-1,CFH... |
Human | HEK293 Cells |
CFHR1 is a secreted protein belonging to the complement factor H protein family.The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR1 binds to Pseudomonas aeruginosa elongation factor ... | |||
TMPK-00182 |
PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated
PDL1,PD-L1B7 homolog 1,P... |
Human | HEK293 Cells |
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecu... | |||
TMPY-06756 |
NR1H4 Protein, Mouse, Recombinant (His)
nuclear receptor subfamily 1, group H, mem... |
Mouse | E. coli |
NR1H4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.80 kDa. | |||
TMPY-05238 |
PD-L1 Protein, Human, Recombinant (hFc), Biotinylated
PDL1,B7H1,PDCD1LG1 |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-04648 |
PD-L1 Protein, Human, Recombinant (mFc)
CD274 molecule,B7-H1,PDL1,PDCD |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.7 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-00112 |
Tomoregulin-1 Protein, Human, Recombinant (hFc)
TR-1,C9orf2,transmembrane protein with EGF... |
Human | HEK293 Cells |
TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul... | |||
TMPY-05651 |
ICOS Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
H4,inducible T-cell co-stimulator,Ly11... |
Mouse | HEK293 Cells |
ICOS Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q5SUZ7. | |||
TMPY-04991 |
ICOS Protein, Mouse, Recombinant (rFc)
CCLP,Ly115,CRP-1,AILIM,inducible ... |
Mouse | HEK293 Cells |
ICOS Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 40.2 kDa and the accession number is Q5SUZ7. | |||
TMPY-00676 |
PD-L1 Protein, Human, Recombinant (hFc)
PDCD1LG1,B7-H,PDCD1L... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-06276 |
PD-L1 Protein, Human, Recombinant (His & Avi), Biotinylated
PD-L1,PDL1,CD274 molecule,PDCD1LG... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.48 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-06209 |
ICOS Protein, Mouse, Recombinant (His)
CCLP,CRP-1,Ly115,AILIM,inducible ... |
Mouse | HEK293 Cells |
ICOS Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.9 kDa and the accession number is Q5SUZ7. | |||
TMPY-01890 |
CLIC4 Protein, Human, Recombinant (His)
MTCLIC,chloride intracellular channel 4,p6... |
Human | E. coli |
Chloride intracellular channel protein 4, also known as Intracellular chloride ion channel protein p64H1 and CLIC4, is a member of the chloride channel CLIC family. It contains oneGST C-terminal domain. CLIC4 is a member of a family of intracellular chloride channels. It is regulated by p53, c-Myc, and tumor necrosis factor-alpha. CLIC4 is detected in epithelial cells from colon, esophagus and kidney (at protein level). CLIC4 has alternate cellular functions like a potential role in angio... | |||
TMPY-02544 |
FANCA Protein, Human, Recombinant (His)
FA-H,FA1,FAA,FAH,FANCH,F... |
Human | Baculovirus Insect Cells |
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IκB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2. | |||
TMPK-01216 |
SEMA7A Protein, Mouse, Recombinant (His)
Sema7A,H-SEMA-K1,JMH,Semaph |
Mouse | HEK293 Cells |
SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8. | |||
TMPY-00818 |
Granzyme H/GZMH Protein, Human, Recombinant (His)
CTSGL2,CSP-C,CCP-X,granzyme H,CTLA1,CGL-2,... |
Human | HEK293 Cells |
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes (A-G and M) have been identified in the mouse, but only five are known in humans (A, B, H, M, and granzyme 3), and granzyme H appears to be specifically human. Human granzyme H is a neutral serine protease that is expressed predominantly in the lymphokine-activated killer (LAK)/... | |||
TMPK-00741 |
SEMA7A Protein, Human, Recombinant (His)
Semaphorin-L,SEMAK1,CD108,MGC... |
Human | HEK293 Cells |
SEMA7A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is O75326-1. | |||
TMPH-01892 |
ATP4A Protein, Human, Recombinant (His & Myc)
ATP4A,Gastric H(+)/K(+) ATPase subunit alph |
Human | E. coli |
ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.6 kDa and the accession number is P20648. | |||
TMPH-02477 |
ALAS1 Protein, Mouse, Recombinant (His & Myc)
Delta-ALA synthase 1,Delta-aminolevulinate... |
Mouse | E. coli |
ALAS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 72.3 kDa and the accession number is Q8VC19. | |||
TMPH-00119 |
Conglutin-7 Protein, Arachis hypogaea, Recombinant (His)
2S protein 1,Conglutin-7,Seed storage protein SSP2,... |
Arachis hypogaea | E. coli |
Weak inhibitor of trypsin. Conglutin-7 Protein, Arachis hypogaea, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.0 kDa and the accession number is Q6PSU2. | |||
TMPJ-00761 |
FTH Protein, Human, Recombinant (His)
FTHL6,Cell proliferation-inducing gene 15 ... |
Human | E. coli |
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of... | |||
TMPJ-00638 |
PD-L1 Protein, Cynomolgus, Recombinant (His)
B7-H,B7-H1,PDL1,PDCD... |
Cynomolgus | HEK293 Cells |
PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accession number is G7PSE7. | |||
TMPJ-00637 |
PD-L1 Protein, Cynomolgus, Recombinant (hFc)
B7-H,PD-L1B7 homolog 1,P... |
Cynomolgus | HEK293 Cells |
PD-L1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 73 KDa and the accession number is G7PSE7. | |||
TMPH-01166 |
CGAS Protein, Human, Recombinant (His)
Cyclic GMP-AMP synthase,cGAMP synthase,CGA... |
Human | E. coli |
CGAS Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-01336 |
REG3A Protein, Human, Recombinant (His)
HIP/PAP,INGAP,REG3,PAP1,PAP-H,reg... |
Human | HEK293 Cells |
REG3A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is Q06141-1. | |||
TMPY-02013 |
CD300A Protein, Human, Recombinant (His)
IRC2,CLM-8,IRC1/IRC2,CMRF35H9,CD300a molec... |
Human | HEK293 Cells |
CD300A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.8 kDa and the accession number is Q9UGN4-1. | |||
TMPY-03768 |
CD300A Protein, Human, Recombinant (hFc)
CMRF-35H,CMRF-35-H9,CMRF35-H,IGSF... |
Human | HEK293 Cells |
CD300A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q9UGN4-1. | |||
TMPH-00973 |
DHX36 Protein, Human, Recombinant (His & Myc)
DEAH-box protein 36,G4R1,ATP-dependent DNA... |
Human | E. coli |
DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is Q9H2U1. | |||
TMPJ-01010 |
PLA2G16 Protein, Human, Recombinant (His)
Renal Carcinoma Antigen NY-REN-65,HRAS-Like Suppres... |
Human | E. coli |
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models. | |||
TMPJ-01111 |
TSTA3 Protein, Human, Recombinant (His)
GDP-L-Fucose Synthase,Short-Chain... |
Human | E. coli |
GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II. | |||
TMPY-04092 |
Histone H4 Protein, Human, Recombinant
HIST1H4E,H4FK,H... |
Human | E. coli |
Histone H4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.4 kDa and the accession number is B2R4R0. | |||
TMPJ-00483 |
DFF45 Protein, Human, Recombinant (His)
DNA Fragmentation Factor Subunit Alpha,DFF45,H<... |
Human | E. coli |
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression. | |||
TMPY-03061 |
CFHR2 Protein, Human, Recombinant (His)
HFL3,FHR2,CFHL2,complement factor... |
Human | HEK293 Cells |
CFHR2 belongs to the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secr... | |||
TMPY-04582 |
ABO Protein, Human, Recombinant (hFc)
NAGAT,A3GALNT,ABO blood group,GTB,A3GALT1 |
Human | HEK293 Cells |
ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase) is a Protein Coding gene. Homologous glycosyltransferases α-(1→3)-N-acetylgalactosaminyltransferase (GTA) and α-(1→3)-galactosyltransferase (GTB) catalyze the final step in ABO(H) blood group A and B antigen synthesis through sugar transfer from activated donor to the H antigen acceptor. These enzymes have a GT-A fold type with characteristic mobile polypeptide loops that cover the active site upon substra... | |||
TMPJ-00679 |
SGTA Protein, Human, Recombinant (His)
α-SGT,Alpha-SGT,SGT,Small Glutamine-Rich T... |
Human | E. coli |
Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV... | |||
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