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109

抑制剂 & 化合物

56

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T4316	ML365	Potassium Channel	Membrane transporter/Ion channel
	ML365 是有效的，选择性的双孔结构域钾通道TASK1/KCNK3抑制剂，IC50为 4 nM。它可用于检查 TASK1 通道的特定作用。
T0280	Spiperone 螺哌隆,Spiroperidol,Spiropitan	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Spiperone (Spiropitan) 是多巴胺 D2、血清素5-HT1A 和血清素5-HT2A 拮抗剂。它是广泛使用的药理学工具。它具有研究神经系统疾病的潜力。
TP1088	N-Acetylcarnosine N-Acetyl-L-carnosine,N-乙酰肌肽	Others	Others
	N-Acetylcarnosine (N-Acetyl-L-carnosine) 是一种含有组氨酸的天然二肽，是药理学上主要的 L-carnosine 的来源。它是一种眼科药物，对人类白内障具有潜在的应用价值。
T12146	N-Desmethyl-Apalutamide N-Desmethyl Apalutamide,N-去甲基阿帕鲁胺杂质	P450; Androgen Receptor	Endocrinology/Hormones; Metabolism
	N-Desmethyl-Apalutamide 是一种 Apalutamide 的活性代谢产物，主要由 CYP2C8 和 CYP3A4 介导形成。它是一种低活性的雄激素受体拮抗剂，其作用力是 Apalutamide 活性的三分之一。它是中等至强的CYP3A4和CYP2B6诱导剂，并具有优异的血浆蛋白结合浓度。
T15233	Endovion NS3728	Chloride channel	Membrane transporter/Ion channel
	Endovion (NS3728) 是阴离子通道抑制剂和 Anoctamin-1 (ANO 1) 通道抑制剂，也是特异性的 VRAC/VSOAC 阻断剂。
T22416	RO495 CS-2667	Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	RO495 (CS-2667) 是一种有效的非受体酪氨酸蛋白激酶2抑制剂。
TN6963	Hentriacontane	NF-κB	NF-κB
	Hentriacontane 是一种天然产物，具有多种药理作用，包括抗炎、抗肿瘤和抗菌活性。
T11016	DGAT-1 inhibitor 2	Transferase	Metabolism
	DGAT-1 inhibitor 2是有效的DGAT-1抑制剂，具有减肥功效。
T24932	Vatanidipine AE-0047,AE 0047,AE0047	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Vatanidipine (AE0047) 是一种新型的双氢吡啶(DHP)型钙通道阻滞剂，具有缓慢起效的药理作用。在各种实验性高血压模型中观察到缓慢起效和持久的降压作用。
T0797	Cimetidine 西米替汀,SKF-92334,西咪替丁	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cimetidine (SKF-92334) 是一种可口服的可逆组胺H2受体拮抗剂，Ki 为 0.6 μM。它抑制胃酸分泌，以及胃蛋白酶和胃泌素的输出，具有抗癌和抗炎活性。
T1540	Doxepin hydrochloride Toruan,Doxepin HCl,Aponal,Novoxapin,盐酸多塞平	P450; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Doxepin hydrochloride (Aponal) 是一种可口服的三环抗抑郁剂，是选择性组胺受体 H1拮抗剂。它也是 CYP450抑制剂，抑制 CYP450 2C19和 CYP450 1A2。
T12654	(Rac)-Acolbifene (Rac)-EM-652,EM-343,阿考比芬	Estrogen Receptor/ERR	Endocrinology/Hormones
	(Rac)-Acolbifene (EM-343) 是 Acolbifene 的外消旋形式。Acolbifene 是一种 estrogen receptor 拮抗剂。(Rac)-Acolbifene 显示出抗雌激素和雌激素活性。 (Rac)-Acolbifene 包含哌啶环，显示出良好的药理作用，RBA=380。
T5159	Olodaterol hydrochloride BI-1744 HCl,盐酸奥达特罗,BI 1744 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Olodaterol hydrochloride (BI-1744 HCl) 是一种长效的、选择性 β2-adrenoceptor(β2-AR) 激动剂 (EC50=0.1 nM；pKi= 9.14 for human β2-adrenoceptor)，可用于慢性阻塞性肺疾病 (COPD) 和肺纤维化的研究。
T21777	VU0359595 VU0359595-1,CID-53361951,ML-270	Phospholipase	Metabolism
	VU0359595 (ML-270)是一种选择性磷脂酶 D1 (PLD1) 抑制剂，IC50 值为 3.7 nM。VU0359595 对 PLD1 的选择性比 PLD2 (IC50=6.4 μM) 高 1700 倍以上。VU0359595 可用于癌症、糖尿病、神经退行性疾病和炎性疾病等疾病研究。
T67917	ML353 VU0478006	Potassium Channel	Membrane transporter/Ion channel
	ML353 (VU0478006)是 TREK-1和 TREK-2的选择性激活剂，是 mGlu5 沉默变构调节剂 (SAM) 的选择性配体(Ki =18.2 nM)。 ML353 有作为解决 SAM 体内固有活性或药物阻断的潜力。
T4688	Pipequaline hydrochloride PK-8165 hydrochloride,盐酸哌夸林	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Pipequaline hydrochloride (PK-8165 hydrochloride) 是一种苯二氮卓受体部分激动剂，有抗焦虑作用。
T14978	CL-82198	MMP	Proteases/Proteasome
	CL-82198 是 MMP-13选择性抑制剂。它能够与 MMP-13 的整个 S1' 口袋结合，这是其对 MMP-13 选择性和对其他 MMP 缺乏抑制活性的基础。它可用于研究骨关节炎。
T21720	GP-82996 Cdk4/6 Inhibitor IV,CINK4	CDK	Cell Cycle/Checkpoint
	GP-82996 (CINK4) (CINK4) 是 CDK4/6的药理学抑制剂。GP-82996 对 CDK4/cyclin D1、CDK6/cyclin D1 和 Cdk5/p35 的 IC50s 分别为 1.5、5.6 和 25 μM。GP-82996 诱导肿瘤细胞 U2OS 的凋亡，可用于癌症研究。
T35028	Valiglurax VU2957,VU 0652957,VU 2957,VU-0652957,VU0652957,VU-2957	GluR	Neuroscience
	Valiglurax (VU2957)，也称为 VU0652957和 VU2957，是一种强效、选择性、中枢神经系统渗透剂，可口服生物利用的 mGlu4正变构调节剂。VU2957具有良好的跨物种的体内外药理学和药代动力学性质。VU2957被评估为治疗帕金森病的临床前开发候选药物。
T0005	Aspirin 阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA	Mitophagy; Virus Protease; COX; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Aspirin (Acetylsalicylic Acid) 是一种选择性 COX 抑制剂，具有多种药理活性。它是组蛋白去乙酰化酶抑制剂，可上调细胞周期阻滞蛋白 p21，抑制携带 COX-1 的卵巢 Y 细胞。它还抑制 HUVEC 和新生大鼠心室心肌细胞中 COX-2 的表达，分别减少 PG 的产生和 ERK 和 NF-KB 的下调。
T0455	Clozapine 氯氮平,HF 1854,LX 100-129	Dopamine Receptor; Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Clozapine (HF 1854) 是一种三环二苯二氮卓类药物，属于非典型抗精神病药物。它结合几种类型的中枢神经系统受体，并显示出独特的药理学特征。它是一种血清素拮抗剂，与 5-HT 2A/2C 受体亚型具有强结合力。它还对几种多巴胺能受体表现出很强的亲和力，但对多巴胺 D2 受体仅表现出较弱的拮抗作用，这种受体通常被认为可调节精神抑制活性。
T1787	Levobupivacaine	Sodium Channel	Membrane transporter/Ion channel
	Levobupivacaine 是一种氨基酰胺类局麻药，属于n-alkylsubstituted pipecoloxylidide 家族。它是bupivacaine 的 S-对映异构体。
Fr13587	7-Chloro-4-(piperazin-1-yl)quinoline
	7-Chloro-4-(piperazin-1-yl)quinolone 结构是药物化学中的重要支架，它单独或与其他活性药效团混合显示出多种药理特性。7-Chloro-4-（piperazin-1-yl）quinolone 是有效的sirtuin 抑制剂，并且抑制 5-羟色胺的摄取，IC50值为 50 μM。7-Chloro-4-(piperazin-1-yl)quinolone 对恶性疟原虫 D10 和 K1 菌株表现出抗疟疾活性，IC50分别为 1.18 μM 和 0.97 μM。
T36520	COR659	Cannabinoid Receptor; GABA Receptor	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	COR659 是一种有效的 GABAB 的阳性变构调节剂。COR659具有缓解大鼠对酒精和巧克力成瘾的作用。
T36008	Nebentan potassium
	Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan potassium inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively[1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo[2]. Nebentan potassium inhibits the specific binding of [125I] endothelin-1 to endothelin ETA and ETB re...
T14940	CGP11952	Others	Others
	CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.
T31178	Dabequin dabechin,G 800
	Dabequin is a derivative of aminoquinoline. It is said to have pharmacological activity against Plasmodium fukiparum.
T23710	Watanidipine dihydrochloride
	Watanidipine dihydrochloride is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.
T20492	Tetragastrin Cholecystokinin tetrapeptide,Gastrin tetrapeptide
	Tetragastrin is the C-terminal tetrapeptide of gastrin. It has the same physiological and pharmacological activity as gastrin.
T29533	ABT-866 ABT 866,A 286666
	ABT-866 is a novel alpha-adrenoceptor agent with mixed pharmacological properties.
T28822	SNAP 398299 SNAP-398299,SNAP398299
	SNAP 398299, a galanin receptor antagonist, is a potential novel pharmacological treatment for mood disorders.
T23628	AD-2646 AD2646
	AD-2646 is a new quinoline derivative. It also has similar pharmacological properties to tricyclic antidepressants.
T19182	Afegostat D-Tartrate Isofagomine D-Tartrate,D-Isofagomine D-Tartrate	Others	Others
	Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
T25542	Isamfazone Isamfazona,Isamfazonum
	Isamfazone is utilized in the chemical and pharmacological studies on substituted pyridazones, the discovery of novel anti-inflammatory agents by aligning screening.
T11893L	Lurasidone metabolite 14326 hydrochloride Lurasidone metabolite 14326 hydrochloride (186204-33-1 free base)	Others	Others
	Lurasidone metabolite 14326 hydrochloride, an active metabolite of the atypical antipsychotic Lurasidone, maintains its significant function in pharmacological efficacy.
T71600	Benazoline oxalate salt
	Benazoline oxalate salt is a pharmacological active compound that inhibits casein kinase Iε (CKIε) or CKIδ phosphorylation of the PER2 protein.
T19181	Afegostat D-Isofagomine,Isofagomine	Others	Others
	Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
T68749	EBOV-IN-C31
	EBOV-IN-C31 is a novel PP1-targeting Ebola Virus (EBOV) inhibitor with improved pharmacological properties.
T30489	BMS 181101 BMS181101,BMS-181101
	BMS-181101 is a novel antidepressant that has pharmacological characteristics as a serotonin reuptake inhibitor and a serotonin 5-HT receptor agonist.
T22975	Methyl α-Linolenyl Fluorophosphonate	Others	Others
	Methyl α-Linolenyl Fluorophosphonate is an inhibitor of phospholipases. Methyl α-Linolenyl Fluorophosphonate (MLnFP), an analog of methyl Arachidonyl Fuorophosphonate (MAFP), has not been completely investigated for its pharmacological activity.
T34819	Tetragastrin HCl Trp-Met-Asp-Phe hydrochloride,Tetragastrin hydrochloride
	Tetragastrin HCl is the HCl salt of Tetragastrin, the C-terminal tetrapeptide of gastrin. It has the same physiological and pharmacological activity as gastrin.
T33607	NBI-34041 NBI34041,SB 723620,SB-723620,SB723620
	NBI-34041 is an effective and high-affinity CRF1 receptor antagonist that effectively reduces endocrine responses to CRF(1) receptor-mediated pharmacological and behavioral challenges.
T23653	Afegostat HCl Afegostat,AT-2101,Afegostat hydrochloride,AT2101
	Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug for the treatment of certain forms of
T39795	Tricarbonyldichlororuthenium(II) dimer CORM-2
	Tricarbonyldichlororuthenium(II) dimer, a pharmacological CO donor, prevents ischemia/reperfusion (I/R)-induced oxidative damage to the gastric mucosa by enhancing gastric blood flow (GBF) and reducing DNA oxidation and systemic inflammatory response.
T75002	Antidepressant agent 3
	Antidepressant agent 3, 一种具有口服活性的抗抑郁剂，具备抗抑郁、抗焦虑、性能增强及促智活性。
T68257	Hydromethylthionine HBr
	Hydromethylthionine, also known as LMTM and Leucomethylene Blue, is a apotent tau aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. Hydromethylthionine showed pharmacological activity on brain structure and function as both monotherapy and as an add-on to symptomatic treatment in certain patients with Alzheimer’s disease.
T78564	Depramine GP 31406
	Depramine (GP 31406) 是三环抗抑郁剂，具药理活性。该化合物可抑制乙酰胆碱酯酶、Mg2+-ATPase 与 Na+/K+ ATPase 活性。
T71160	Levomepromazine HCl
	Levomepromazine HCl is a phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine.
T76572	Acetyl neurotensin (8-13)
	Acetyl neurotensin (8-13) 是神经降压素类似物，具有完全结合和药理活性。
T68822	Tyrphostin AG17
	Tyrphostin AG17 is a biochemical that promotes adipocyte apoptosis in vivo and is an effective modulator of adipocyte differentiation and WAT hypertrophy in vitro and in vivo. It is thought to possibly be useful as a pharmacological obesity treatment. It is a tyrosine kinase antagonist that has also been found to inhibit tumor cell growth.

化合物

Cat.No: T4316

Target: Potassium Channel

Cat.No: T0280

Synonym: 螺哌隆,Spiroperidol,Spiropitan

Target: Dopamine Receptor

N-Acetylcarnosine

Cat.No: TP1088

Synonym: N-Acetyl-L-carnosine,N-乙酰肌肽

Target: Others

N-Desmethyl-Apalutamide

Cat.No: T12146

Synonym: N-Desmethyl Apalutamide,N-去甲基阿帕鲁胺杂质

Target: P450, Androgen Receptor

Cat.No: T15233

Synonym: NS3728

Target: Chloride channel

Cat.No: T22416

Synonym: CS-2667

Target: Tyrosine Kinases, JAK

Cat.No: TN6963

Target: NF-κB

DGAT-1 inhibitor 2

Cat.No: T11016

Target: Transferase

Cat.No: T24932

Synonym: AE-0047,AE 0047,AE0047

Target: Calcium Channel

Cat.No: T0797

Synonym: 西米替汀,SKF-92334,西咪替丁

Target: Histamine Receptor

Doxepin hydrochloride

Cat.No: T1540

Synonym: Toruan,Doxepin HCl,Aponal,Novoxapin,盐酸多塞平

Target: P450, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor

(Rac)-Acolbifene

Cat.No: T12654

Synonym: (Rac)-EM-652,EM-343,阿考比芬

Target: Estrogen Receptor/ERR

Olodaterol hydrochloride

Cat.No: T5159

Synonym: BI-1744 HCl,盐酸奥达特罗,BI 1744 hydrochloride

Target: Adrenergic Receptor

Cat.No: T21777

Synonym: VU0359595-1,CID-53361951,ML-270

Target: Phospholipase

Cat.No: T67917

Synonym: VU0478006

Target: Potassium Channel

Pipequaline hydrochloride

Cat.No: T4688

Synonym: PK-8165 hydrochloride,盐酸哌夸林

Target: GABA Receptor

Cat.No: T14978

Target: MMP

Cat.No: T21720

Synonym: Cdk4/6 Inhibitor IV,CINK4

Target: CDK

Cat.No: T35028

Synonym: VU2957,VU 0652957,VU 2957,VU-0652957,VU0652957,VU-2957

Target: GluR

Cat.No: T0005

Synonym: 阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA

Target: Mitophagy, Virus Protease, COX, Autophagy

Cat.No: T0455

Synonym: 氯氮平,HF 1854,LX 100-129

Target: Dopamine Receptor, Adrenergic Receptor, AChR

Levobupivacaine

Cat.No: T1787

Target: Sodium Channel

7-Chloro-4-(piperazin-1-yl)quinoline

Cat.No: Fr13587

Cat.No: T36520

Target: Cannabinoid Receptor, GABA Receptor

Nebentan potassium

Cat.No: T36008

Cat.No: T14940

Target: Others

Cat.No: T31178

Synonym: dabechin,G 800

Watanidipine dihydrochloride

Cat.No: T23710

Cat.No: T20492

Synonym: Cholecystokinin tetrapeptide,Gastrin tetrapeptide

Cat.No: T29533

Synonym: ABT 866,A 286666

Cat.No: T28822

Synonym: SNAP-398299,SNAP398299

Cat.No: T23628

Synonym: AD2646

Afegostat D-Tartrate

Cat.No: T19182

Synonym: Isofagomine D-Tartrate,D-Isofagomine D-Tartrate

Target: Others

Cat.No: T25542

Synonym: Isamfazona,Isamfazonum

Lurasidone metabolite 14326 hydrochloride

Cat.No: T11893L

Synonym: Lurasidone metabolite 14326 hydrochloride (186204-33-1 free base)

Target: Others

Benazoline oxalate salt

Cat.No: T71600

Cat.No: T19181

Synonym: D-Isofagomine,Isofagomine

Target: Others

Cat.No: T68749

Cat.No: T30489

Synonym: BMS181101,BMS-181101

Methyl α-Linolenyl Fluorophosphonate

Cat.No: T22975

Target: Others

Tetragastrin HCl

Cat.No: T34819

Synonym: Trp-Met-Asp-Phe hydrochloride,Tetragastrin hydrochloride

Cat.No: T33607

Synonym: NBI34041,SB 723620,SB-723620,SB723620

Cat.No: T23653

Synonym: Afegostat,AT-2101,Afegostat hydrochloride,AT2101

Tricarbonyldichlororuthenium(II) dimer

Cat.No: T39795

Synonym: CORM-2

Antidepressant agent 3

Cat.No: T75002

Hydromethylthionine HBr

Cat.No: T68257

Cat.No: T78564

Synonym: GP 31406

Levomepromazine HCl

Cat.No: T71160

Acetyl neurotensin (8-13)

Cat.No: T76572

Tyrphostin AG17

Cat.No: T68822

Cat. No.	Product Name	Target	Signaling Pathways
T5722	Nevadensin Pedunculin,石吊兰素,5,7-二羟基-6,8,4'-三甲氧基黄酮	Anti-infection; Antibacterial	Microbiology/Virology
	Nevadensin 是一种重要的草本成分，可抑制雌二醇的生物活化。它具有抗结核分枝杆菌、镇咳、抗炎、抗高血压等多种药理作用。
T4104	Ophiopojaponin C 麦冬皂苷C,Ophiopogonin C	Others	Others
	Ophiopogonin C' pharmacological activities may be related to the substances in nucleus mainly.
T2891	Ammonium glycyrrhizinate Glycamil,Monoammonium glycyrrhizinate,Ammonium Glycyrrhizate,甘草酸单胺,Monoammonium glycyrrhizinate hydrate,Glycyrram	Others	Others
	Ammonium glycyrrhizinate (Glycyrram) 具有抗炎、抗胃溃疡、抗过敏、抗肝炎等药理功能。
T3S1251	Neoruscogenin	ROR	Metabolism
	Neoruscogenin 是甾体 sapogenin 家族的成员，是一种可生物利用且具有高亲和力的核受体RORα (NR1F1)激动剂。
T4878	Hecogenin 海柯吉宁,Hocogenin	Others; Antifungal	Microbiology/Virology; Others
	Hecogenin (Hocogenin), a steroid saponin derived from Agave sisalana, serves as a specific inhibitor for human UDP-glucuronosyltransferases. Notably, it exhibits a broad range of pharmacological activities, such as anti-inflammatory, antifungal, and gastroprotective effects[1].
T7324	Chelidonine hydrochloride	Others	Others
	Chelidonine hydrochloride 是 Chelidonium majus 的生物碱之一，具有广泛的药理活性。
TN7030	Heteroclitin G	Others	Others
	Heteroclitin G 被发现是 KIS 补血活性的潜在生物标志物，定量分析为进一步药理研究提供了研究基础。
T7443	4'-Methoxychalcone 4'-甲氧基查耳酮,4'-甲氧基查尔酮	PARP; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	4'-Methoxychalcone 通过PPARγ活化调节脂肪细胞分化，并调节参与胰岛素敏感性的脂肪组织中各种脂肪因子的表达和分泌，具抗肿瘤和抗炎活性。
TQ0264	Nigakinone 苦木酮碱,苦木酮	Others	Others
	Nigakinone 是一种苦木中含量丰富的生物碱，具有重要的药理活性。
T3O2709	Bronze Red 808猩红,Scarlet 808	Others	Others
	Bronze Red 属于酰胺类有机物，可用于含量测定、鉴定、药理实验等。
T2837	Chrysin 5, 7-Dihydroxyflavone,NSC 407436,白杨素,5,7-Dihydroxyflavone	Estrogen Receptor/ERR; Antioxidant	Endocrinology/Hormones; oxidation-reduction
	Chrysin (5,7-Dihydroxyflavone) 是一种雌激素阻断剂。
T2718	Palmatine chloride	Others; Indoleamine 2,3-Dioxygenase (IDO); Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Metabolism; Others
	Palmatine chloride 是口服具有活力的不可逆 IDO-1抑制剂。它能够减轻结肠损伤，预防肠道菌群失调和调节色氨酸分解代谢，并改善 DSS 诱发的结肠炎。
T5749	10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) 是一种紫杉醇衍生物，具有改进的药理特性和更高的水溶性，用于治疗癌症。
T3362	Eupatilin NSC 122413,异泽兰黄素	PPAR; Autophagy	Autophagy; DNA Damage/DNA Repair; Metabolism
	Eupatilin (NSC-122413) 是一种从青蒿中提取的黄酮，是一种 PPARα 激动剂，具有药理活性。
T5S1882	Songorine 准葛尔乌头碱,Napellonine,Zongorine,Bullatine G	Others; GABA Receptor	Membrane transporter/Ion channel; Neuroscience; Others
	Songorine (Napellonine) 是从乌头属中分离出的一种二萜生物碱，具有抗癌、抗心律不齐和抗炎活性。它是大鼠脑中的GABAA 受体拮抗剂，有用于上皮性卵巢癌的研究潜力。
T2866	Echinocystic acid	Apoptosis; Antioxidant; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Echinocystic acid 是从皂角的果实中提取出来的一种五环三萜，有抗氧化，抗炎症和抗肿瘤作用。
T4S1659	Xanthotoxol 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,花椒毒酚,8-Hydroxypsoralene	Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Xanthotoxol (Psoralen) 是一种具有生物活性的线性呋喃香豆素，具有很强的抗炎、抗氧化、5-HT 拮抗和神经保护作用等药理活性。
T0595	Naringin Naringoside,柚皮苷	Mitophagy; P450; Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Naringin (Naringoside) 是一种黄烷酮糖苷，有抗氧化活性、降血脂、抗癌和抑制细胞色素P450酶的药理作用。
TN1966	N-(3-Methoxybenzyl)Oleamide N-Benzyloleamide,MAC 18:1	Antioxidant	oxidation-reduction
	N-(3-Methoxybenzyl)Oleamide (MAC 18:1) 是一种从 Lepidium meyenii 中分离出来的玛瑙酰胺，对运动引起的疲劳具有药理作用，可能与调节能量代谢和改善抗氧化状态有关。
T5737	euphol	Others; Lipase; Endogenous Metabolite	Metabolism; Others
	Euphol 是从Euphorbia tirucalli 的汁液中分离出来的四环三萜醇，具有抗炎和免疫调节作用，口服具有活力。它通过能够逆机制抑制单酰基甘油脂肪酶 (MGL) 的特性，IC50=315 nM。外周 MGL 抑制能够调节内源性大麻素系统从而阻止炎症性疼痛的发展。
T3373	Columbianadin Zosimin,2-Butenoic acid,二氢欧山芹醇当归酸酯	Apoptosis	Apoptosis
	Columbianadin (Zosimin) 是来自当归的根的主要生物活性成分之一，是一种天然香豆素，具有抗炎和抗癌作用。
TN1046	Murrayone	Others	Others
	Murrayone 是一种提取自M. paniculata 中的含有香豆素的化合物。Murrayone 具有独特的药理特性，可用作防止癌症转移的化学预防剂。
T2817	Picroside II 胡黄连苷II,Vanilloyl catalpol,6-Vanilloylcatalpol,胡黄连苦苷II	Apoptosis; Others; Influenza Virus; NF-κB; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others
	Picroside II (Vanilloyl catalpol) 是从胡黄连提取的一种环烯醚萜类，有神经保护作用，具有抗氧化、抗炎、抗细胞凋亡、免疫调节和抗病毒等药理活性。
TN1714	Grosvenorine 罗汉果黄素,Grosvenorin	Antibacterial	Microbiology/Virology
	Grosvenorine (Grosvenorin) 具有良好的抗菌和抗氧化活性，是罗汉果中主要的黄酮类物质。
T2746	Sophocarpine monohydrate 槐果碱,Sophocarpine,槐果碱水合物	Apoptosis; Influenza Virus; Akt; PI3K; AMPK; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Sophocarpine monohydrate 是从传统草药苦参中提取的一种重要生物碱，具有抗肿瘤活性，可用于肝细胞癌，前列腺癌和结肠直肠癌。苦参具有抗病毒，抗肿瘤和抗炎等多种药理作用。
T6S1101	Astragalin Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,紫云英苷,Kaempferol 3-β-D-glucopyranoside	Apoptosis; NF-κB	Apoptosis; NF-κB
	Astragalin (Kaempferol 3-O-glucoside) 是一种具有生物活性的天然黄酮类化合物。它具有多种药理特性，包括抗氧化、抗炎、抗癌、神经保护和心脏保护特性。
T3920	Pseudoginsenoside F11 Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11	Others; Endogenous Metabolite	Metabolism; Others
	Pseudoginsenoside F11 (Ginsenoside A1) 从人参根和叶中分离得到。PF11在一系列心血管和中枢神经系统疾病中具有广泛的保护作用。
T3S1250	Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside 麦冬苷元-3-O-Α-L-吡喃鼠李糖基(1→2)-Β-D-吡喃葡萄糖苷,Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside	Others	Others
	Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) 是一种从麦冬根中取得的萜类糖苷，对心血管系统有良好的药理作用。
T8250	2,6,6-Trimethyl-2,4-cycloheptadien-1-one	Others	Others
	2,6,6-Trimethyl-2,4-cycloheptadien-1-one 是一种萜类化合物，存在于许多植物中，包括香菜、莳萝和芹菜。它是精油的重要成分，具有多种药用和药理特性。
T1716	Echinacoside	Reactive Oxygen Species; Wnt/beta-catenin	Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells
	Echinacoside 是一种从Cistanche salsa 中分离的苯乙醇类化合物，抑制Wnt/β-catenin 信号通路。它能够激活 Trk 受体及其下游信号通路而起到神经保护作用，还具有显著的抗骨质疏松作用。
T1516	Curcumin Diferuloylmethane,Natural Yellow 3,姜黄素,Indian Saffron,Turmeric yellow	Mitophagy; Epigenetic Reader Domain; Ferroptosis; Influenza Virus; Nrf2; Histone Acetyltransferase; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology
	Curcumin (Natural Yellow 3) 属于酚类天然产物，是一种组蛋白乙酰化转移酶 p300/CREB 的抑制剂 (IC50=25 μM)，具有特异性。Curcumin 具有抗肿瘤、抗炎和抗氧化等多种药理活性。
T2729	Scoparone 滨蒿内酯,Escoparone,Scoparon,Aesculetin dimethyl ether,6,7-dimethoxycoumarin,6,7-Dimethylesculetin	Others	Others
	Scoparone (Aesculetin dimethyl ether) 是分离自毛蒿中，具有抗凝血，抗血管舒张作用和抗炎活性。
T5764	Alliin 蒜氨酸,(S)-3-(Allylsulphinyl)-L-alanine	NF-κB; PPAR	DNA Damage/DNA Repair; Metabolism; NF-κB
	Alliin ((S)-3-(Allylsulphinyl)-L-alanine) 是一种从大蒜中提取的亚砜化合物，具有口服活性，表现出降血糖、抗氧化和抗炎特性。
T6677	Sophocarpine	ERK; p38 MAPK; NF-κB; TLR; COX; HER; JNK; STAT	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Sophocarpine 是一种从传统草药苦参中提取的重要生物碱。苦参具有抗病毒、抗肿瘤和抗炎等多种药理作用。它通过多种机制显著抑制癌细胞的生长，具有抗肿瘤活性。
T2768	Saikosaponin A 柴胡皂苷A,柴胡皂苷 A	NF-κB; Antibacterial; Liver X Receptor	Metabolism; Microbiology/Virology; NF-κB
	Saikosaponin A 是银柴胡中的主要活性成分，有抗炎活性，可上调 LXRα的表达。
T3030	L-Sophoridine L-槐定碱,Sophoridine,Matridin-15-one	Others	Others
	L-Sophoridine (Matridin-15-one) 一种从药用植物中提取的天然产物，具有多种药理作用，包括抗Y 作用，可在体外和体内选择性诱导多种人体Y 细胞凋亡；然而，其作用机制需要进一步阐述。
TN5888	Toddaculin	Others	Others
	Toddaculin 是一种天然香豆素，抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡，具有抗炎活性。
T4749	Squalene 角鲨烯,Nikko Squalane EX,Super Squalene,AddaVax,all-trans-Squalene,trans-Squalene,Spinacene	Reactive Oxygen Species; Endogenous Metabolite; Antifungal	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Squalene (AddaVax) 是胆固醇合成的中间产物，具有降血脂、保肝、心脏保护、抗氧化和抗毒活性等多种药理特性。它还具有抗真菌活性，可用于毛癣菌治疗的相关研究。
T81907	Lucenin 3
	Lucenin 3，一种生物活性类黄酮，具备生物医学领域内的功能性特性。
T82318	Ginsenoside Rs1
	Ginsenoside Rs1为人参根中提取的一种人参皂苷类化合物。
T78504	Lavandoside
	Lavandoside是一种活性化合物，源自薰衣草之花。
T81220	Salvileucantholide
	Salvileucantholide为一种从S. leucantha中提取的二萜类化合物。
T38479	3-Hydroxypyridine
	3-Hydroxypyridine, extracted from Bamboo grass, is a structural analogue of vitamin B6. It exhibits diverse pharmacological properties, including antioxidant activity.
T83601	(+)-Diasyringaresinol
	(+)-Diasyringaresinol 是从 Aquilaria agallocha 提取的一种木质素化合物。
T82336	Ganoderic acid T
	Ganoderic acid T为ganoderma lucidum中的一种天然化合物。
TN6584	Pallidol
	Pallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent.
T81055	Szechenyin A
	Szechenyin A 是Gentianae Szechenyii Spray 成分中的一种化学化合物。
T81195	Schiarisanrin E
	Schiarisanrin E (compound 5)，一种从松台五味子分离出的木脂素。
TN1378	α-Viniferin ALPHA-VINIFERIN,Alpha-葡萄素	P450; NO Synthase; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism
	α-Viniferin 也称为2-芳基苯并呋喃类黄酮，是前列腺素H2合成酶抑制剂。具有抗阿尔茨海默病、抗结核、抗肿瘤、抗炎、抗糖尿病等多种药理活性
T79948	Kadsurenin B
	Kadsurenin B为PAF（platelet-activating factor）拮抗剂，展现出神经保护作用。该化合物在药理学领域显示出广泛的研究潜力，包括抗菌、抗炎、神经保护、抗氧化、抗血小板聚集、细胞毒性和抗寄生虫等效能。
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天然产物

Cat.No: T5722

Synonym: Pedunculin,石吊兰素,5,7-二羟基-6,8,4'-三甲氧基黄酮

Target: Anti-infection, Antibacterial

Ophiopojaponin C

Cat.No: T4104

Synonym: 麦冬皂苷C,Ophiopogonin C

Target: Others

Ammonium glycyrrhizinate

Cat.No: T2891

Synonym: Glycamil,Monoammonium glycyrrhizinate,Ammonium Glycyrrhizate,甘草酸单胺,Monoammonium glycyrrhizinate hydrate,Glycyrram

Target: Others

Cat.No: T3S1251

Target: ROR

Cat.No: T4878

Synonym: 海柯吉宁,Hocogenin

Target: Others, Antifungal

Chelidonine hydrochloride

Cat.No: T7324

Target: Others

Cat.No: TN7030

Target: Others

4'-Methoxychalcone

Cat.No: T7443

Synonym: 4'-甲氧基查耳酮,4'-甲氧基查尔酮

Target: PARP, PPAR

Cat.No: TQ0264

Synonym: 苦木酮碱,苦木酮

Target: Others

Cat.No: T3O2709

Synonym: 808猩红,Scarlet 808

Target: Others

Cat.No: T2837

Synonym: 5, 7-Dihydroxyflavone,NSC 407436,白杨素,5,7-Dihydroxyflavone

Target: Estrogen Receptor/ERR, Antioxidant

Palmatine chloride

Cat.No: T2718

Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase

10-Deacetyl-7-xylosyl paclitaxel

Cat.No: T5749

Synonym: 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside

Target: Others, Microtubule Associated

Cat.No: T3362

Synonym: NSC 122413,异泽兰黄素

Target: PPAR, Autophagy

Cat.No: T5S1882

Synonym: 准葛尔乌头碱,Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Echinocystic acid

Cat.No: T2866

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Cat.No: T4S1659

Synonym: 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,花椒毒酚,8-Hydroxypsoralene

Target: Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite

Cat.No: T0595

Synonym: Naringoside,柚皮苷

Target: Mitophagy, P450, Endogenous Metabolite, Autophagy

N-(3-Methoxybenzyl)Oleamide

Cat.No: TN1966

Synonym: N-Benzyloleamide,MAC 18:1

Target: Antioxidant

Cat.No: T5737

Target: Others, Lipase, Endogenous Metabolite

Cat.No: T3373

Synonym: Zosimin,2-Butenoic acid,二氢欧山芹醇当归酸酯

Target: Apoptosis

Cat.No: TN1046

Target: Others

Cat.No: T2817

Synonym: 胡黄连苷II,Vanilloyl catalpol,6-Vanilloylcatalpol,胡黄连苦苷II

Target: Apoptosis, Others, Influenza Virus, NF-κB, Reactive Oxygen Species

Cat.No: TN1714

Synonym: 罗汉果黄素,Grosvenorin

Target: Antibacterial

Sophocarpine monohydrate

Cat.No: T2746

Synonym: 槐果碱,Sophocarpine,槐果碱水合物

Target: Apoptosis, Influenza Virus, Akt, PI3K, AMPK, Autophagy

Cat.No: T6S1101

Synonym: Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,紫云英苷,Kaempferol 3-β-D-glucopyranoside

Target: Apoptosis, NF-κB

Pseudoginsenoside F11

Cat.No: T3920

Synonym: Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11

Target: Others, Endogenous Metabolite

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside

Cat.No: T3S1250

Synonym: 麦冬苷元-3-O-Α-L-吡喃鼠李糖基(1→2)-Β-D-吡喃葡萄糖苷,Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside

Target: Others

2,6,6-Trimethyl-2,4-cycloheptadien-1-one

Cat.No: T8250

Target: Others

Cat.No: T1716

Target: Reactive Oxygen Species, Wnt/beta-catenin

Cat.No: T1516

Synonym: Diferuloylmethane,Natural Yellow 3,姜黄素,Indian Saffron,Turmeric yellow

Target: Mitophagy, Epigenetic Reader Domain, Ferroptosis, Influenza Virus, Nrf2, Histone Acetyltransferase, HDAC, Autophagy

Cat.No: T2729

Synonym: 滨蒿内酯,Escoparone,Scoparon,Aesculetin dimethyl ether,6,7-dimethoxycoumarin,6,7-Dimethylesculetin

Target: Others

Cat.No: T5764

Synonym: 蒜氨酸,(S)-3-(Allylsulphinyl)-L-alanine

Target: NF-κB, PPAR

Cat.No: T6677

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

Cat.No: T2768

Synonym: 柴胡皂苷A,柴胡皂苷 A

Target: NF-κB, Antibacterial, Liver X Receptor

Cat.No: T3030

Synonym: L-槐定碱,Sophoridine,Matridin-15-one

Target: Others

Cat.No: TN5888

Target: Others

Cat.No: T4749

Synonym: 角鲨烯,Nikko Squalane EX,Super Squalene,AddaVax,all-trans-Squalene,trans-Squalene,Spinacene

Target: Reactive Oxygen Species, Endogenous Metabolite, Antifungal

Cat.No: T81907

Ginsenoside Rs1

Cat.No: T82318

Cat.No: T78504

Salvileucantholide

Cat.No: T81220

3-Hydroxypyridine

Cat.No: T38479

(+)-Diasyringaresinol

Cat.No: T83601

Ganoderic acid T

Cat.No: T82336

Cat.No: TN6584

Cat.No: T81055

Schiarisanrin E

Cat.No: T81195

Cat.No: TN1378

Synonym: ALPHA-VINIFERIN,Alpha-葡萄素

Target: P450, NO Synthase, Prostaglandin Receptor

Cat.No: T79948

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