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Search Results for " il-1β "

Targets Recommended: JNK

140

抑制剂 & 化合物

29

天然产物

2

化合物库

43

重组蛋白

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Cat. No.	Product Name
L8720	细胞焦亡化合物库		1066 compounds
	1066 种细胞焦亡相关的化合物，可以用于细胞焦亡相关研究。
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

细胞焦亡化合物库

Cat.No: L8720

Compounds: 1066

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

Cat. No.	Product Name	Target	Signaling Pathways
T8477	IQ-3	JNK	MAPK
	IQ3 是c-JNK 家族选择性抑制剂，对JNK3 的选择性更好。它对JNK1、JNK2 和 JNK3 的Kd 值分别为0.24 μM、0.29 μM 和 0.066 μM。
T21629	Loxapine	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Loxapine 是 D2DR 和 D4DR 抑制剂和5-羟色胺能受体拮抗剂，是一种抗精神病药物，主要用于治疗精神分裂症。
T8692	(Rac)-Benpyrine	TNF	Apoptosis
	(Rac)-Benpyrine 是一种有效且具有口服活性的 TNF-α 抑制剂，是Benpyrine 的外消旋体。它可研究TNF-α介导的炎症和自身免疫性疾病。
T8828	CP 424174	IL Receptor	Immunology/Inflammation
	CP 424174 是一种具有可逆性的 IL-1β抑制剂(IC50:210 nM)，也能够间接性抑制 NLRP3。
T8381	Amodiaquine	Others; Histone Methyltransferase; Parasite	Chromatin/Epigenetic; Microbiology/Virology; Others
	Amodiaquine 是一种合成的4-氨基喹啉类抗疟剂，是一种有口服活性的组胺 N-甲基转移酶抑制剂。它也是一种Nurr1激动剂，有抗炎活性，可特异性结合Nurr1的配体结合域，EC50约为20 μM。
T8553	BC-1471	Others	Others
	BC-1471 是STAM 结合蛋白（STAMBP）去泛素酶抑制剂。BC-1471 抑制 NALP7（NACHT, LRR 和 PYD 结构域蛋白 7）的炎症小体活性。
T6927	Pamapimod R1503,帕吡莫德,Ro4402257	p38 MAPK; Autophagy	Autophagy; MAPK
	Pamapimod (R1503) 是一种新型的选择性 p38 丝裂原活化蛋白激酶抑制剂，对于p38α和p38β的IC50分别为 14 nM 和 480 nM，Ki 分别为 1.3 nM 和 120 nM，对 p38δ 或 p38γ 亚型没有活性，可研究类风湿关节炎和其他自身免疫性疾病。
T27695	JTE-607 JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱	Cysteine Protease	Proteases/Proteasome
	JTE-607 HCl 是高选择性的炎性细胞因子合成抑制剂，可保护小鼠免受内毒素休克。它作用于 LPS 刺激的人 PBMC，抑制TNF-α(IC50:11 nM)、IL-1β(IC50:5.9 nM)、IL-6(IC50:8.8 nM)、IL-8(IC50:7.3 nM)和IL-10(IC50:9.1 nM)。
T41302	Itaconate-alkyne ITalk	Others	Others
	Itaconate-alkyne (ITalk) 是一种生物正交探针，用于对炎症性巨噬细胞中的衣康酸进行定量和位点特异性化学蛋白质组学分析，并能够对其直接靶标进行生化评估和蛋白质组学分析。
T1412	Loxapine succinate Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt,丁二酸洛沙平,琥珀酸洛沙平	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Loxapine succinate (Loxapac) 是D2/D4多巴胺受体，5-羟色胺受体抑制剂，用于精神分裂症。
T22698	TLR3-IN-1 CU CPT 4a	TLR	Immunology/Inflammation
	TLR3-IN-1 (CU CPT 4a) 是一种选择性的TLR3信号抑制剂，在 RAW 264.7 细胞中 IC50 为 3.44 μM。它可以抑制 TLR3/dsRNA 复合物介导的下游信号通路，并抑制全细胞中 TNF-α 和 IL-1β 的产生。
T0089	Cetirizine dihydrochloride 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cetirizine dihydrochloride (UCB P071) 是羟嗪的羧化代谢物，是特异性口服有效的 H1 受体长效拮抗剂。它标记抗过敏特性，抑制过敏反应期间嗜酸性粒细胞趋化，可有效治疗过敏性鼻炎、确诊荨麻疹和花粉诱发的哮喘。
T0381	Amodiaquine dihydrochloride dihydrate Amodiaquine hydrochloride,阿莫地喹盐酸盐,Amodiaquin dihydrochloride dihydrate	Histone Methyltransferase; Parasite; Histamine Receptor	Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) 是一种具有口服活性的组胺 N-甲基转移酶抑制剂，也是一种Nurr1激动剂，可特异性结合Nurr1的配体结合域，EC50约为20 μM。它是 4-氨基喹啉衍生物，具有抗疟和抗炎特性。
T78707	IL-1β-IN-2
	IL-1β-IN-2为大麻酚衍生物，该化合物作为IL-1β抑制剂表现出优良效力，兼具抗炎及镇痛特性。
T74819	IL-1β-IN-1
	IL-1β-IN-1 是一种大麻二酚衍生物，是一种有效的 IL-1β抑制剂。IL-1β-IN-1 具有抗炎和镇痛作用。
T3147	Pyrrolidinedithiocarbamate ammonium PDTC,Pyrrolidinedithiocarbamate,吡咯烷二硫代氨基甲酸铵,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate,吡咯烷二硫代甲酸铵	NF-κB	NF-κB
	Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt) 是一种选择性的、能透过血脑屏障的NF-κB 抑制剂。
T7162	R1487 Hydrochloride R1487 (Hydrochloride)	p38 MAPK; Autophagy	Autophagy; MAPK
	R1487 Hydrochloride (R1487(Hydrochloride)) 是一种可口服的高选择性 p38α 抑制剂，对 p38α 和 p38β 的Kd 值分别为 0.2 nM 和 29 nM。
T36534	SDZ 224-015 SDZ 224015	IL Receptor; Caspase	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	SDZ 224-015 是白细胞介素-1β（IL-1β）转化酶和 Caspase-1 的口服活性抑制剂。SDZ 224-015 具有抗 COVID-19 和抗炎活性，可减少角叉菜胶诱导的大鼠爪子水肿。
T73695	Canakinumab ACZ 885,Ilaris	IL Receptor	Immunology/Inflammation
	Canakinumab (ACZ885) 是一种重组人靶向 IL-1β 单克隆抗体。Canakinumab 显示出对人类和绒猴 IL-1β 具有抑制作用， IC50 值为分别为 43.6 和 40.8 pM。Canakinumab 具有抗炎活性，通过中和 IL-1β 信号来抑制与自身免疫性疾病相关的炎症。Canakinumab 可用于治疗痛风和冠状动脉疾病。
T4450	GIBH-130	IL Receptor; TNF; Interleukin	Apoptosis; Immunology/Inflammation
	GIBH130 是一种有效的神经炎症抑制剂，可作用于活化的小胶质细胞，明显抑制IL-1β的分泌(IC50:3.4 nM)。
T15622	JNJ-54175446 JNJ-5446	P2X Receptor	Membrane transporter/Ion channel; Neuroscience
	JNJ-54175446 (JNJ-5446) 是一种具有中枢神经系统渗透性和选择性的 P2X7 受体拮抗剂，可减弱小胶质细胞 IL-1β/IL-18 的释放，可用于研究抑郁症。
T8706	STAMBP-IN-1	Others	Others
	STAMBP-IN-1是一种新型选择性去泛素酶 STAM 结合蛋白 (STAMBP) 拮抗剂，可降低 NALP7 蛋白水平并抑制 TLR 激动后 IL-1β 的释放。
T36347	Ac-YVAD-CMK Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK	IL Receptor; Caspase; Immunology/Inflammation related; Pyroptosis	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) 是一种选择性的、不可逆的Caspase-1抑制剂，并能抑制焦亡作用、IL-1β和IL-18。Ac-YVAD-CMK 显示出神经保护和抗炎的能力。
T21738	PF-9184	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	PF-9184 是一种有效且高度选择性的人微粒体前列腺素 E 合酶 1 (mPGES-1) 的抑制剂，IC50 值为 16.5 nM。PF-9184 体外抑制 IL-1β 诱导的 PGE2 合成。
T28958	TG6-129 TG6 129	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	TG6-129 是有效的EP2受体选择性拮抗剂，可降低 butaprost 诱导的 P388D1 巨噬细胞中炎症因子的表达。
T77675	TNKS-2-IN-1	PARP; Wnt/beta-catenin; Antibiotic	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Microbiology/Virology; Stem Cells
	TNKS-2-IN-1 是一种 TNKS-2 抑制剂。TNKS-2-IN-1 对 TNKS-1 和 TNKS-2有抑制作用，IC50 分别为 259 nM 和 1100 nM。TNKS-2-IN-1 具有抗菌活性，对大肠杆菌和金黄色葡萄球菌具有抑制作用。TNKS-2-IN-1 抑制 NLRP3 炎症小体（IC505μM）通过抑制ATP刺激的J1A.774细胞释放IL-1β。
T9645	CU-115 N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide	TLR	Immunology/Inflammation
	CU-115 是一种有效的，选择性的 TLR8 拮抗剂。CU-115对 TLR8 和 TLR7的 IC50分别为1.04 µM 和=>50 µM。THP-1 细胞中，CU-115 减少了 R-848 激活的 TNF-α 和 IL-1β 的产生。
T61392	NLRP3-IN-10 ZVN26391	NOD	Immunology/Inflammation; NF-κB
	NLRP3-IN-10 (ZVN26391) 是强效的 NLRP3 抑制剂，抑制 IL-1β 释放的 IC50 为 251.1 nM。NLRP3-IN-10 通过减弱 ASC 斑点形成来抑制 NLRP3炎症小体激活。
T79906	ADS032 BT-032	NOD	Immunology/Inflammation; NF-κB
	ADS032 (BT-032)是一种 NLRP1和 NLRP3 抑制剂，具有抗炎活性,抑制 NLRP1和NLRP3 的激活，抑制 Nigericin 引起的IL-1β产生，可用于研究呼吸道炎症或感染。
T11742	K-7174	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	K-7174 是一种新型细胞粘附抑制剂，抑制由 IL-1β 或 TNF-α 诱导的血管细胞粘附分子 1 (VCAM-1) 的表达。
T67924	ABzOH
	ABzOH 是一种苯甲酸衍生物，结构类似于阿司匹林等非甾体抗炎药，具有抗炎、抗肿瘤和抗增殖作用。ABzOH 不仅可以抑制肿瘤坏死因子- α (TNF-a)、白细胞介素-1β (IL-1β)和白细胞介素-6 (IL-6)等促炎细胞因子的表达还对乳腺癌、肺癌和胰腺癌具有抑制作用。
T77579	JC2-11	IL Receptor; Dehydrogenase; ROS; Caspase; NOD-like Receptor (NLR); AIM2	Apoptosis; Immunology/Inflammation; Metabolism; Proteases/Proteasome
	JC2-11 是一种对炎症有抑制作用的化合物。JC2-11 对含有募集结构域的蛋白质 NLRC 4、黑色素瘤 2 中缺失 (AIM 2) 和非典型 (NC) 炎症小体有抑制作用，通过破坏活性氧的产生和 caspase-1 的活性来抑制炎症小体的活化。JC2-11 减少了炎症小体中 caspase-1 (p20) 的分泌、gasdermin D (GSDMD) 的裂解、IL-1β 和乳酸脱氢酶 (LDH) 的释放。
T5821	BC-1215	Others; Ligand for E3 Ligase	Others; PROTAC
	BC-1215 是一种 F-box protein 3 抑制剂。它能够稳定 TRAF1-TRAF6 来抑制 Fbxo3-TRAF 激活途径。它与 ApaG 相互作用，阻碍来自人 PBMC 广谱 TH1 细胞因子的分泌。
T76711	Golimumab MK-8259,SCH 900259,CNTO-148	TNF	Apoptosis
	Golimumab (CNTO-148) 是一种有效的人源化抗 TNFα IgG1κ单克隆抗体。Golimumab 具有抗炎和抗癌活性，对 IL-6 和 IL-1β 的产生有抑制作用，可诱导细胞凋亡。Golimumab 可用来预防炎症发生和软骨或骨骼的破坏，可用于研究类风湿性关节炎和癌症。
T3701	MCC950 CP-456773	NOD	Immunology/Inflammation; NF-κB
	MCC950 (CP-456773) 是NLRP3的选择性抑制剂，能够作用于BMDMs(IC50:7.5 nM) 和 HMDMs(IC50:8.1 nM)。
T6090	Belnacasan VX-765	Caspase	Apoptosis; Proteases/Proteasome
	Belnacasan (VX-765) 是一种具有口服活性的 IL 转换酶/caspase-1 抑制剂，是 VRT-043198 的口服生物活性前药，作用于外周血单核细胞，可抑制 LPS 诱导的 IL-1β 和 IL-18 释放。
T13063	T6167923	MyD88	Immunology/Inflammation
	T6167923是一种有效的、选择性的MyD88依赖性信号通路抑制剂。T6167923 与 MyD88 的 Toll/IL1 受体 (TIR) 结构域结合良好，破坏 MyD88 的同二聚体形成。T6167923 抑制 NF-κB 驱动的葡萄球菌肠毒素AP (SEAP) 活性，并且改善抗炎活性，对 IFN-γ，IL-1β，IL-6 和 TNF-α 的 IC50分别为 2.7 μM，2.9 μM，2.66 μM 和 2.66 μM。
T35593	Semapimod tetrahydrochloride CPSI-2364 tetrahydrochloride	TLR; MAPK	Immunology/Inflammation; MAPK
	Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) 是一种合成鸟腙丝裂原活化蛋白激酶阻滞剂,也是促炎细胞因子生成抑制剂，干扰巨噬细胞和小胶质细胞功能。Semapimod tetrahydrochloride 可抑制 TLR4 信号传导，抑制 TNF-α、IL-1β 和 IL-6，可用于研究克罗恩病和其他炎症。
T13375	YQ128	IL Receptor; NOD-like Receptor (NLR); NOD; Interleukin	Immunology/Inflammation; NF-κB
	YQ128 是选择性 NLRP3 炎性体抑制剂(IC50:0.30 µM)。它能显著的、选择性抑制 IL-1β的产生，但不影响 TNF-α 的产生。它能够透过血脑屏障到达中枢神经系统。它具有抗炎作用。
TP2015L	HS 014 acetate(207678-81-7 free base)	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	HS 014 acetate(207678-81-7 free base) 是一种有效的选择性黑皮质素 MC4 受体拮抗剂（克隆的人 MC4、MC1、MC3 和 MC5 受体的 Ki 值分别为 3.16、108、54.4 和 694 nM）。体内中枢给药后增加大鼠的食物摄入和小鼠的伤害感受。还抑制室旁下丘脑中 IL-1β 诱导的 Fos 表达。
T41142	EM 163	IL Receptor; p38 MAPK; MyD88	Immunology/Inflammation; MAPK
	EM 163是一种 TIR-TIR 相互作用抑制剂，它是MyD88蛋白的TIR（Toll/白细胞介素-1受体）结构域拟态。EM 163针对IL-1受体中的TIR 结构域，阻断与MyD88的相互作用。EM 163抑制葡萄球菌肠毒素B（SEB）引起的体内炎症细胞因子的产生。EM 163能保护小鼠免受SEB 冲击引起的死亡。在体外的大鼠海马神经元中，EM 163阻断p38的激活和IL-1β对化学诱导的长期电位（LTP）引发的蛋白质合成的抑制作用。
T1813	VGX-1027 VGX1027,VGX 1027,GIT 27	IL Receptor; TNF; Interleukin	Apoptosis; Immunology/Inflammation
	VGX-1027 (GIT 27) 是一种口服有效的异恶唑化合物，靶向巨噬细胞，减少促炎性介质 TNF-α、IL-1β和 IL-10 的产生，具有免疫调节特性。它通过限制细胞因子介导的免疫炎症而具有抗糖尿病作用。
T5416	T-5224	MMP	Proteases/Proteasome
	T-5224 是选择性的转录因子c-Fos/activator protein (AP)-1抑制剂，具有抗炎作用，能够特异性抑制 c-Fos/c-Jun 的 DNA 结合活性，但对其他转录因子的结合活性无影响。它抑制 IL-1β 诱导的 Mmp-3、Mmp-13、Adamts-5 转录上调。
T38361	GSK717	IL Receptor; NOD	Immunology/Inflammation; NF-κB
	GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导，抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T16570	Pralnacasan VX-740,HMR 3480	Others	Others
	Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential for osteoarthritis and rheumatoid a
T69745	GDC-2394
	GDC-2394 是一种口服有效、选择性的 NLRP3抑制剂，同时也抑制 IL-1β，IC50为 0.4 μM (human IL-1β) 和 0.1 μM (mouse IL-1β)。GDC-2394 抑制 NLRP3诱导的 caspase-1活性，但不抑制 NLRC4 依赖的炎症小体激活。
T26626	AN3485 Hydrochloride
	AN3485 Hydrochloride inhibits TLR2-, TLR3-, TLR4- and TLR5-mediated TNF-α, IL-1β and IL-6.
T75113	GLPG2534 GLPG-2534	IRAK	Immunology/Inflammation; NF-κB
	GLPG2534 是一种具有口服活性、选择性和有效性的 IRAK4 抑制剂，具有抗炎活性。GLPG2534 对人和小鼠 IRAK4 具有抑制作用，可用于研究银屑病和特应性皮炎。
T76731	Gevokizumab
	Gevokizumab 是一种有效的抗 IL-1β抗体，通过变构机制负向调节 IL-1β信号。Gevokizumab 降低 IL-1β对 IL-1受体 I 型 (IL-1RI) 信号受体的结合亲和力，而不影响 IL-1反调节诱饵受体 (IL-1 受体 II 型)。
T77077	Lutikizumab
	Lutikizumab (ABT-981) 为一种针对IL-1α和IL-1β的双特异性抗体，具备双变量结构域。通过结合IL-1α和IL-1β，Lutikizumab 能有效抑制其活性，主要应用于骨关节炎的研究领域。

化合物

Cat.No: T8477

Target: JNK

Cat.No: T21629

Target: Dopamine Receptor, 5-HT Receptor

(Rac)-Benpyrine

Cat.No: T8692

Target: TNF

Cat.No: T8828

Target: IL Receptor

Cat.No: T8381

Target: Others, Histone Methyltransferase, Parasite

Cat.No: T8553

Target: Others

Cat.No: T6927

Synonym: R1503,帕吡莫德,Ro4402257

Target: p38 MAPK, Autophagy

Cat.No: T27695

Synonym: JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱

Target: Cysteine Protease

Itaconate-alkyne

Cat.No: T41302

Synonym: ITalk

Target: Others

Loxapine succinate

Cat.No: T1412

Synonym: Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt,丁二酸洛沙平,琥珀酸洛沙平

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T22698

Synonym: CU CPT 4a

Target: TLR

Cetirizine dihydrochloride

Cat.No: T0089

Synonym: 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl

Target: Histamine Receptor

Amodiaquine dihydrochloride dihydrate

Cat.No: T0381

Synonym: Amodiaquine hydrochloride,阿莫地喹盐酸盐,Amodiaquin dihydrochloride dihydrate

Target: Histone Methyltransferase, Parasite, Histamine Receptor

Cat.No: T78707

Cat.No: T74819

Pyrrolidinedithiocarbamate ammonium

Cat.No: T3147

Synonym: PDTC,Pyrrolidinedithiocarbamate,吡咯烷二硫代氨基甲酸铵,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate,吡咯烷二硫代甲酸铵

Target: NF-κB

R1487 Hydrochloride

Cat.No: T7162

Synonym: R1487 (Hydrochloride)

Target: p38 MAPK, Autophagy

Cat.No: T36534

Synonym: SDZ 224015

Target: IL Receptor, Caspase

Cat.No: T73695

Synonym: ACZ 885,Ilaris

Target: IL Receptor

Cat.No: T4450

Target: IL Receptor, TNF, Interleukin

Cat.No: T15622

Synonym: JNJ-5446

Target: P2X Receptor

Cat.No: T8706

Target: Others

Cat.No: T36347

Synonym: Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK

Target: IL Receptor, Caspase, Immunology/Inflammation related, Pyroptosis

Cat.No: T21738

Target: Prostaglandin Receptor

Cat.No: T28958

Synonym: TG6 129

Target: Prostaglandin Receptor

Cat.No: T77675

Target: PARP, Wnt/beta-catenin, Antibiotic

Cat.No: T9645

Synonym: N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide

Target: TLR

Cat.No: T61392

Synonym: ZVN26391

Target: NOD

Cat.No: T79906

Synonym: BT-032

Target: NOD

Cat.No: T11742

Target: IL Receptor, TNF

Cat.No: T67924

Cat.No: T77579

Target: IL Receptor, Dehydrogenase, ROS, Caspase, NOD-like Receptor (NLR), AIM2

Cat.No: T5821

Target: Others, Ligand for E3 Ligase

Cat.No: T76711

Synonym: MK-8259,SCH 900259,CNTO-148

Target: TNF

Cat.No: T3701

Synonym: CP-456773

Target: NOD

Cat.No: T6090

Synonym: VX-765

Target: Caspase

Cat.No: T13063

Target: MyD88

Semapimod tetrahydrochloride

Cat.No: T35593

Synonym: CPSI-2364 tetrahydrochloride

Target: TLR, MAPK

Cat.No: T13375

Target: IL Receptor, NOD-like Receptor (NLR), NOD, Interleukin

HS 014 acetate(207678-81-7 free base)

Cat.No: TP2015L

Target: Melanocortin Receptor

Cat.No: T41142

Target: IL Receptor, p38 MAPK, MyD88

Cat.No: T1813

Synonym: VGX1027,VGX 1027,GIT 27

Target: IL Receptor, TNF, Interleukin

Cat.No: T5416

Target: MMP

Cat.No: T38361

Target: IL Receptor, NOD

Cat.No: T16570

Synonym: VX-740,HMR 3480

Target: Others

Cat.No: T69745

AN3485 Hydrochloride

Cat.No: T26626

Cat.No: T75113

Synonym: GLPG-2534

Target: IRAK

Cat.No: T76731

Cat.No: T77077

Cat. No.	Product Name	Target	Signaling Pathways
TN6722	Terminolic acid 2α,6β,23-trihydroxyl oleanolic acid	Antibacterial	Microbiology/Virology
	Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) 是一种从 Combretum racemosum 中分离得到的五环三萜糖苷，可通过与 IL-1β 和 IL-6 的受体活性位点结合抑制促炎细胞因子，并通过与 IL-4 受体结合位点结合增强抗炎细胞因子。它还表现出适度的抗菌活性。
T9352	hydrocotarnine	Others	Others
	hydrocotarnine 是 Cbl 的抑制剂。
T2893	Muscone 3-Methylcyclopentadecanone,Methylexaltone,麝香酮	MMP; TNF; NF-κB; NOD-like Receptor (NLR); P-gp; Interleukin	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB; Proteases/Proteasome
	Muscone (3-Methylcyclopentadecanone) 是中药麝香的一种主要活性单体。它抑制NF-κB 和NLRP3炎性小体的活化，显著降低炎性细胞因子水平，并最终改善心脏功能和存活率。
T5779	MOSLOFLAVONE	IL Receptor; Virus Protease; TNF; Antibacterial	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Mosloflavone 从Scutellaria baicalensis Georgi 中分离出的类黄酮，具有抗EV71活性。它可抑制铜绿假单胞菌的毒力和生物膜形成，有作为杀菌剂的潜力。它在病毒感染的初始阶段抑制 VP2 病毒复制和蛋白质表达，并抑制病毒 VP2 衣壳蛋白合成。
TN1520	Isoforskolin Coleonol B	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Isoforskolin 源自毛喉鞘蕊花，可减少人单核白细胞中 TNF-α、IL-1β、IL-6 和 IL-8 的分泌。Isoforskolin 可用于治疗莱姆关节炎的研究。
T2720	Ginsenoside Rc Panaxoside Rc,人参皂苷Rc,人参皂苷 Rc	Others; TNF; GABA Receptor; Interleukin	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; Others
	Ginsenoside Rc (Panaxoside Rc) 是人参中的一种人参皂苷，可抑制 TNF-α 和 IL-1β 的表达。它增强 GABA 受体 A 介导的离子通道电流。
T2856	(-)-Epicatechin L-Epicatechin,表儿茶素,Epicatechin,(-)-Epicatechol,表儿茶精	Ferroptosis; COX; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
	(-)-Epicatechin (Epicatechin) 是一种 COX-1 的抑制剂，通过阻断 NF-κB 的 p65 亚基的核定位来抑制 IL-1β 诱导的 iNOS 表达。
TC0036	Compound Lup-20(29)-en-3-yl acetate	IL Receptor; VEGFR; Others; TNF; COX	Angiogenesis; Apoptosis; Immunology/Inflammation; Neuroscience; Others; Tyrosine Kinase/Adaptors
	Lup-20(29)-en-3-yl acetate 是 Lupeol 的衍生物，通过下调 TNF-α、IL-1β、MCP-1、COX-2、VEGF 和颗粒酶 B 来抑制类风湿性关节炎的进展。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
TN5171	Tricetin	Apoptosis; Others; Nrf2	Apoptosis; Immunology/Inflammation; Others
	Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用（PPI）的强效竞争性抑制剂，通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路，保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1（PS-1）表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症，保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。
T5680	Aloin(mixture of A&B) 芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷	MMP; IL Receptor; Antibacterial; Antifungal	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Aloin (mixture of A&B) 是一种从芦荟中分离出来的蒽醌衍生物。它是刺激性粒细胞基质金属蛋白酶的有效抑制剂。它具有多种生物活性，如抗炎、抗菌、抗真菌、抗氧化、抗肿瘤、抗糖尿病和免疫活性。
T6S1579	Monotropein 水晶兰苷,Monotropeine	Others	Others
	Monotropein (Monotropeine) 是从Morinda officinalis 中获得，能够抑制硫酸葡聚糖硫酸钠诱导的结肠炎小鼠模型中炎性因子的表达。
T2932	Ginsenoside Rh1 Sanchinoside B2,人参皂苷 Rh1,人参皂苷Rh1,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1	IL Receptor; TNF; Endogenous Metabolite; PPAR; Interleukin	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism
	Ginsenoside Rh1 (Sanchinoside B2) 是人参的一种主要成分，具有抗炎作用，抑制PPAR-γ，TNF-α，IL-6和IL-1β的表达。
T2S0342	Armillarisin A	Others; Interleukin	Immunology/Inflammation; Others
	Armillarisin A 具有上调 IL-4和下调 IL-1β 的效果，对溃疡性结肠炎具有潜在的研究价值。
T6S1597	Mulberroside A 桑皮苷 A,桑皮苷A	TNF; Tyrosinase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Mulberroside A 是桑中的一种主要活性成分，可降低TNF-α、IL-1β和IL-6的表达，抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化。它抑制蘑菇酪氨酸酶，具有抗炎和抗细胞凋亡作用。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
T3887	Rosarin	Others	Others
	Rosarin 是从玫瑰红景天中分离出来的肉桂醇糖苷。它抑制小鼠肾脏和大脑前额皮层中促炎因子 iNOS，IL-1β 和 TNF-α 的表达。它具有抗炎和神经保护作用。
T2768	Saikosaponin A 柴胡皂苷A,柴胡皂苷 A	NF-κB; Antibacterial; Liver X Receptor	Metabolism; Microbiology/Virology; NF-κB
	Saikosaponin A 是银柴胡中的主要活性成分，有抗炎活性，可上调 LXRα的表达。
T2993	Cordycepin 3'-Deoxyadenosine,虫草素	MMP; TNF; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞中，剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。
T6S1538	Neochlorogenic acid 新绿原酸,trans-5-O-Caffeoylquinic acid,Neochlorogenate,金银花,5-O-Caffeoylquinic acid	TNF; NF-κB; COX; Antibacterial; Interleukin	Apoptosis; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) 是在干果和其他植物中发现的一种多酚类天然产物，可抑制iNOS 和COX-2蛋白表达，抑制TNF-α和IL-1β产生，还抑制磷酸化的NF-κB p65和p38 MAPK 活化。
T3803	Specnuezhenide 特女贞苷,Nuzhenide,Nuezhenide	Others; NF-κB; Wnt/beta-catenin	Cytoskeletal Signaling; NF-κB; Others; Stem Cells
	Specnuezhenide (Nuezhenide) 是分离自女贞子的果实中。它可抑制 NF-κB 和 wnt/β-catenin 信号传导，进而抑制 IL-1β 诱导的软骨细胞炎症。它可在骨关节炎 (OA) 大鼠模型中发挥抗炎作用。
T6S0077	Byakangelicol	COX	Immunology/Inflammation; Neuroscience
	Byakangelicol 是一种分离自白芷的白三醇，能够抑制环加氧酶-2的表达及活性，从而减少白细胞介素-1β诱导的 A549 细胞中前列腺素 E2 的释放。它可用于研究气道炎症。
T26545	Acanthoic acid NP1302,NP 1302: NP-1302
	Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum with anti-inflammatory activities. Acanthoic acid downregulates LPS-induced IL-1β, IL-6 and TNF-α production in BALF, attenuates lung histopathologic changes, and inhibits infla
TN6445	Cyclo(Gly-L-Pro)
	Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO pr
TN5238	Viscidulin II	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates.
TN4879	Questinol	IL Receptor; TNF; COX; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit the production of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6 and inhibit NO an
T38838	QS-21 Stimulon,QS-21
	QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1.
T79992	Sarglaroids F	Caspase	Apoptosis; Proteases/Proteasome
	Sarglaroids F（化合物6）为从草珊瑚根部提取的抗炎剂，影响K+外排并降低Caspase-1(P20)水平以抑制LPS/ATP诱导的IL-1β释放，对RAW264.7细胞无细胞毒性。
T79970	Taxamairin B
	Taxamairin B是有效的抗炎化合物，能显著抑制LPS诱导的RAW264.7细胞中促炎因子(TNF-α, IL-1β和IL-6)表达及NO、ROS生成，并对LPS引起的急性肺损伤模型小鼠具有保护效果。

天然产物

Terminolic acid

Cat.No: TN6722

Synonym: 2α,6β,23-trihydroxyl oleanolic acid

Target: Antibacterial

Cat.No: T9352

Target: Others

Cat.No: T2893

Synonym: 3-Methylcyclopentadecanone,Methylexaltone,麝香酮

Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin

Cat.No: T5779

Target: IL Receptor, Virus Protease, TNF, Antibacterial

Cat.No: TN1520

Synonym: Coleonol B

Target: IL Receptor, TNF

Cat.No: T2720

Synonym: Panaxoside Rc,人参皂苷Rc,人参皂苷 Rc

Target: Others, TNF, GABA Receptor, Interleukin

(-)-Epicatechin

Cat.No: T2856

Synonym: L-Epicatechin,表儿茶素,Epicatechin,(-)-Epicatechol,表儿茶精

Target: Ferroptosis, COX, Endogenous Metabolite

Compound Lup-20(29)-en-3-yl acetate

Cat.No: TC0036

Target: IL Receptor, VEGFR, Others, TNF, COX

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Cat.No: TN5171

Target: Apoptosis, Others, Nrf2

Aloin(mixture of A&B)

Cat.No: T5680

Synonym: 芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷

Target: MMP, IL Receptor, Antibacterial, Antifungal

Cat.No: T6S1579

Synonym: 水晶兰苷,Monotropeine

Target: Others

Ginsenoside Rh1

Cat.No: T2932

Synonym: Sanchinoside B2,人参皂苷 Rh1,人参皂苷Rh1,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1

Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin

Cat.No: T2S0342

Target: Others, Interleukin

Cat.No: T6S1597

Synonym: 桑皮苷 A,桑皮苷A

Target: TNF, Tyrosinase, Interleukin

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: T3887

Target: Others

Cat.No: T2768

Synonym: 柴胡皂苷A,柴胡皂苷 A

Target: NF-κB, Antibacterial, Liver X Receptor

Cat.No: T2993

Synonym: 3'-Deoxyadenosine,虫草素

Target: MMP, TNF, Antibacterial, Antibiotic, Autophagy

Neochlorogenic acid

Cat.No: T6S1538

Synonym: 新绿原酸,trans-5-O-Caffeoylquinic acid,Neochlorogenate,金银花,5-O-Caffeoylquinic acid

Target: TNF, NF-κB, COX, Antibacterial, Interleukin

Cat.No: T3803

Synonym: 特女贞苷,Nuzhenide,Nuezhenide

Target: Others, NF-κB, Wnt/beta-catenin

Cat.No: T6S0077

Target: COX

Cat.No: T26545

Synonym: NP1302,NP 1302: NP-1302

Cyclo(Gly-L-Pro)

Cat.No: TN6445

Cat.No: TN5238

Target: IL Receptor, TNF

Cat.No: TN4879

Target: IL Receptor, TNF, COX, Prostaglandin Receptor

Cat.No: T38838

Synonym: Stimulon,QS-21

Cat.No: T79992

Target: Caspase

Cat.No: T79970

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02134	IL-1 beta/IL-1F2 Protein, Mouse, Recombinant Il-1b,IL-1beta,白细胞介素,interleukin 1, β,inte...	Mouse	E. coli
	IL-1 beta/IL-1F2 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P10749.
TMPK-00515	IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) Interleukin-1 β,IL-1 beta,IL1B,IL...	Cynomolgus	E. coli
	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The p...
TMPK-00162	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated IL-1 β,IL-1β,IL-1 β/...	Human	E. coli
	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C...
TMPK-00161	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi) Interleukin-1 beta,IL-1 β,IL-1β,<...	Human	E. coli
	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. ...
TMPY-00854	IL-1 alpha/IL-1A Protein, Human, Recombinant IL-1F1,interleukin 1, α,interleukin 1, alpha,白介素,	Human	HEK293 Cells
	IL-1 alpha/IL-1A Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18 kDa and the accession number is P01583.
TMPY-01738	IL-1 alpha/IL-1A Protein, Mouse, Recombinant interleukin 1, α,IL-1 α/IL1A,interleukin 1...	Mouse	E. coli
	IL-1 alpha/IL-1A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is P01582.
TMPJ-00162	IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) Hematopoietin-1,Interleukin-1 Alpha,白介素,IL-1 α,...	Human	HEK293 Cells
	IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 54 KDa and the accession number is P01583.
TMPY-01049	IL-1 beta/IL-1F2 Protein, Human, Recombinant IL-1 beta,interleukin 1, beta,IL-1B,interl...	Human	E. coli
	IL-1 beta/IL-1F2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is P01584.
TMPY-02568	IL-1 beta/IL-1F2 Protein, Canine, Recombinant interleukin 1, beta,IL-1 β,interleukin 1, β	Canine	E. coli
	IL-1 beta/IL-1F2 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.6 kDa and the accession number is Q28292.
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2V,IL<...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-02445	IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant interleukin 1, beta,IL-1 β,白介素,interleukin 1, β,白细胞...	Rhesus	E. coli
	IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P48090.
TMPY-04096	ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) Ly84,St2-rs1,T1,ST2L,T1/ST2,Fit-1,St2,interleukin 1 receptor...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P14719-1.
TMPY-01999	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His) IL-1,IL1-β,白介素,IL1-BETA,白细胞介素,	Human	E. coli
	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.3 kDa and the accession number is P01584.
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) interleukin 1 α,IL1,白介素,IL-1F1,IL...	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage...
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His) IL1RL1,IL‑1 R4,DER4,ST2,IL33R,int...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-02227	IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) 白细胞介素,interleukin 1, beta,白介素,interleukin 1, β,IL-1...	Rat	E. coli
	IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is Q63264-1.
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Protein T1,suppression of tumorigenicity 2,Ly84,DER4,Fit-1,L...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPK-00638	IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) IL1RL2,IL-1 Rrp2,IL-36R,IL	Cynomolgus	HEK293 Cells
	IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.1 kDa and the accession number is G8F338.
TMPK-00333	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated IL-1 Rrp2,IL-1 R6,IL1RL2,IL	Human	HEK293 Cells
	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1.
TMPK-00332	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) IL1RL2,IL-1 R6,IL-1 Rrp2,IL	Human	HEK293 Cells
	IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1.
TMPH-03497	IL-1 beta Protein, Sheep, Recombinant (His)	Sheep	P. pastoris (Yeast)
	IL-1 beta Protein, Sheep, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.7 kDa and the accession number is P21621.
TMPH-03743	IL-1 beta Protein, Zebrafish, Recombinant (His)	Danio rerio (Zebrafish)	E. coli
	IL-1 beta Protein, Zebrafish, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is E6N152.
TMPH-03744	IL-1 beta Protein, Zebrafish, Recombinant (His & Myc)	Danio rerio (Zebrafish)	E. coli
	IL-1 beta Protein, Zebrafish, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.9 kDa and the accession number is E6N152.
TMPY-05836	IL-1 alpha/IL-1A Protein, Rat, Recombinant interleukin 1, alpha,IL-1 α/IL1A,interleuk...	Rat	E. coli
	IL-1 alpha/IL-1A Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.80 kDa and the accession number is P16598.
TMPY-00851	IL-1 R9 Protein, Human, Recombinant (hFc) IL-1R9,interleukin 1 receptor accessory protein-lik...	Human	HEK293 Cells
	IL-1 R9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q9NP60.
TMPY-01740	IL-1 R9 Protein, Human, Recombinant (His) IL-1R9,IL1RAPL-2,IL1R9,TIGIRR-1,i...	Human	HEK293 Cells
	IL-1 R9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.7 kDa and the accession number is Q9NP60.
TMPK-00920	IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His) IL-1A,白介素,IL-1 alpha,Interleukin-1 alpha,<...	Cynomolgus	HEK293 Cells
	The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
TMPH-03496	IL-1 beta Protein, Sheep, Recombinant (E. coli, His)	Sheep	E. coli
	IL-1 beta Protein, Sheep, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.7 kDa and the accession number is P21621.
TMPJ-00161	IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated Hematopoietin-1,IL-1 α,IL-1 Alpha,白细胞介素,In...	Human	E. coli
	IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated is expressed in E. coli expression system with C-Avi tag. The predicted molecular weight is 19 KDa and the accession number is P01583.
TMPH-02438	IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)	Rhesus	E. coli
	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag...
TMPY-02397	IL-1 beta/IL-1F2 Protein, Feline, Recombinant interleukin 1, beta,白细胞介素,白介素,interleukin 1, β,IL-1...	Feline	E. coli
	IL-1 beta/IL-1F2 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P41687.
TMPY-04011	IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant 白介素,IL1-β,interleukin 1, beta,interleukin 1, β,...	Rabbit	E. coli
	IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P14628.
TMPY-03493	ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) St2,ST2L,T1/ST2,interleukin 1 receptor-like 1,DER4,St2-rs1,F...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P14719-1.
TMPY-05452	ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) interleukin 1 receptor-like 1	Cynomolgus	HEK293 Cells
	ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.1 kDa and the accession number is XP_005575214.1.
TMPY-01886	IL-1 beta/IL-1F2 Protein, Rat, Recombinant (His) IL-1 β,interleukin 1, β,interleukin 1, beta	Rat	E. coli
	IL-1 beta/IL-1F2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.1 kDa and the accession number is Q63264-1.
TMPY-02147	ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) ST2L,FIT-1,IL‑1 R4,interleukin 1 receptor-like 1,ST...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.3 kDa and the accession number is Q01638-1.
TMPJ-01392	IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His) IL-1 β,IL1B,IL-1 beta,Interleukin...	Cavia porcellus	E. coli
	Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and...
TMPY-00612	IL-1 beta/IL-1F2 Protein, Sus scrofa (Pig), Recombinant interleukin 1, β,IL-1 β,interleukin 1, beta	Sus scrofa (Pig)	E. coli
	IL-1 beta/IL-1F2 Protein, Sus scrofa (Pig), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is P26889.
TMPJ-00849	ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) Protein ST2,IL-1 R4,IL-33R,ST2V,suppressio...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-110 KDa and the accession number is P14719-2.
TMPK-01029	IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His) C3orf13,IL1RAP,IL-1 R3,IL-1 RAcP	Mouse	HEK293 Cells
	Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disease pathogenesis. For example, in asthma, both IL-33 and IL-1 are of major importance, as are IL-36 and IL-1 in psoriasis.
TMPJ-00968	NAMPT Protein, Human, Recombinant (His) PBEF,PBEF1,Nicotinamide phosphoribosyltransferase,NAmPRTase,...	Human	E. coli
	Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine “visfatin”. PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are ...
TMPY-02549	GBP1 Protein, Human, Recombinant (His) guanylate binding protein 1,GBP1	Human	HEK293 Cells
	Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secre...

重组蛋白

IL-1 beta/IL-1F2 Protein, Mouse, Recombinant

Cat.No: TMPY-02134

Species: Mouse

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00515

Species: Cynomolgus

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00162

Species: Human

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00161

Species: Human

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Human, Recombinant

Cat.No: TMPY-00854

Species: Human

Expression System: HEK293 Cells

IL-1 alpha/IL-1A Protein, Mouse, Recombinant

Cat.No: TMPY-01738

Species: Mouse

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00162

Species: Human

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Human, Recombinant

Cat.No: TMPY-01049

Species: Human

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Canine, Recombinant

Cat.No: TMPY-02568

Species: Canine

Expression System: E. coli

ST2/IL-1 RL1 Protein, Human, Recombinant

Cat.No: TMPY-00850

Species: Human

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant

Cat.No: TMPY-02445

Species: Rhesus

Expression System: E. coli

ST2/IL-1 RL1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04096

Species: Mouse

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01999

Species: Human

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

Cat.No: TMPY-06981

Species: Human

Expression System: E. coli

ST2/IL-1 RL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01359

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00849

Species: Human

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)

Cat.No: TMPY-02227

Species: Rat

Expression System: E. coli

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Cat.No: TMPJ-00850

Species: Mouse

Expression System: HEK293 Cells

IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00638

Species: Cynomolgus

Expression System: HEK293 Cells

IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00333

Species: Human

Expression System: HEK293 Cells

IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00332

Species: Human

Expression System: HEK293 Cells

IL-1 beta Protein, Sheep, Recombinant (His)

Cat.No: TMPH-03497

Species: Sheep

Expression System: P. pastoris (Yeast)

IL-1 beta Protein, Zebrafish, Recombinant (His)

Cat.No: TMPH-03743

Species: Danio rerio (Zebrafish)

Expression System: E. coli

IL-1 beta Protein, Zebrafish, Recombinant (His & Myc)

Cat.No: TMPH-03744

Species: Danio rerio (Zebrafish)

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Rat, Recombinant

Cat.No: TMPY-05836

Species: Rat

Expression System: E. coli

IL-1 R9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00851

Species: Human

Expression System: HEK293 Cells

IL-1 R9 Protein, Human, Recombinant (His)

Cat.No: TMPY-01740

Species: Human

Expression System: HEK293 Cells

IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00920

Species: Cynomolgus

Expression System: HEK293 Cells

IL-1 beta Protein, Sheep, Recombinant (E. coli, His)

Cat.No: TMPH-03496

Species: Sheep

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPJ-00161

Species: Human

Expression System: E. coli

IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)

Cat.No: TMPH-02438

Species: Rhesus

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Feline, Recombinant

Cat.No: TMPY-02397

Species: Feline

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant

Cat.No: TMPY-04011

Species: Rabbit

Expression System: E. coli

ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03493

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05452

Species: Cynomolgus

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-01886

Species: Rat

Expression System: E. coli

ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His)

Cat.No: TMPY-02147

Species: Human

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)

Cat.No: TMPJ-01392

Species: Cavia porcellus

Expression System: E. coli

IL-1 beta/IL-1F2 Protein, Sus scrofa (Pig), Recombinant

Cat.No: TMPY-00612

Species: Sus scrofa (Pig)

Expression System: E. coli

ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)

Cat.No: TMPJ-00849

Species: Mouse

Expression System: HEK293 Cells

IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)

Cat.No: TMPK-01029

Species: Mouse

Expression System: HEK293 Cells

NAMPT Protein, Human, Recombinant (His)

Cat.No: TMPJ-00968

Species: Human

Expression System: E. coli

GBP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02549

Species: Human

Expression System: HEK293 Cells

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