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Search Results for " atr "

Targets Recommended: ATM/ATR ATM/ATR

294

抑制剂 & 化合物

98

天然产物

1

化合物库

1

TargetMol 试剂盒

36

重组蛋白

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Cat. No.	Product Name
L9210	儿童药物库		972 compounds
	972 种儿童药物的独特集合，可用于高通量筛选和高内涵筛选

化合物库

儿童药物库

Cat.No: L9210

Compounds: 972

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0136	ATM/ATR inhibitor kit ATM/ATR inhibitor kit

TargetMol 试剂盒

ATM/ATR inhibitor kit

Cat.No: CL0136

Cat. No.	Product Name	Target	Signaling Pathways
T3032	VE-821 ATR Inhibitor IV	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	VE-821 (ATR Inhibitor IV) 是一种有效的 ATP 竞争性的ATR 抑制剂，Ki 为 13 nM，IC50为 26 nM。
T10406	Tuvusertib M1774,ATR inhibitor 1	Apoptosis; ATM/ATR; Others; Chk	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others; PI3K/Akt/mTOR signaling
	Tuvusertib (M1774) 是一种可口服的共济失调毛细血管扩张和 Rad3相关(ATR)激酶抑制剂(Ki< 1 µΜ)，具有选择性和潜在的抗肿瘤活性。Tuvusertib 选择性抑制 ATR 活性，阻断丝氨酸/苏氨酸蛋白激酶检查点激酶1 (CHK1)的下游磷酸化，从而抑制 DNA 损伤检查点激活，破坏 DNA 损伤修复，诱导肿瘤细胞凋亡。
T62083	Camonsertib ATR inhibitor 4,RP-3500	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Camonsertib (RP-3500) 是一种选择性的、口服具有活力的 ATR 激酶抑制剂 (ATRi)，在生化试验中的 IC50: 1.00 nM，表现出有效的抗肿瘤作用。RP-3500 对 ATR 的选择性是 mTOR 的 30 倍 (IC50: 120 nM)，是 ATM、DNA-PK 和 PI3Kα 激酶的 2,000 倍以上。
T40212	ATR-IN-4
	ATR-IN-4, a potent inhibitor of ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase), restricts the growth of DU145 prostate cancer cells and NCI-H460 lung cancer cells, with IC 50 values of 130.9 nM and 41.33 nM, respectively.
T40077	ATR-IN-9
	ATR-IN-9 is a highly effective inhibitor of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). With an IC50 value as low as 10 nM, ATR-IN-9 demonstrates exceptional potency.
T9321	zapnometinib ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid	Influenza Virus; MEK; Antibacterial	MAPK; Microbiology/Virology
	Zapnometinib (ATR-002) 是 CI-1040 的活性代谢物，是一种 MEK 抑制剂，IC50值为 5.7 nM，有抗流感病毒的抗病毒和抗菌活性。
T10407	Gartisertib ATR inhibitor 2	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	ATR inhibitor 2 is an orally active, ATP-competitive, and selective ATR inhibitor (Ki <150 pM) with antitumor activity. ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation (IC50: 8 nM).
T12225	Nevanimibe ATR-101,PD-132301	Others	Others
	Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
T62084	ATR-IN-8
	ATR-IN-8 是一种 ATR 的有效抑制剂。其中 ATR 是同源重组修复途径中的关键酶，是 PIKK 家族成员之一。ATR-IN-8 对癌症疾病表现出潜在的研究价值。
T62548	ATR-IN-17
	ATR-IN-17 是一种 ATR 激酶的有效抑制剂，在 LoVo 细胞中具有良好的抗癌效果 (IC50: 1 nM)。
T78959	ATR-IN-23	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	ATR-IN-23 (Compound 34) 是一种选择性ATR抑制剂，其IC50为 1.5 nM。该化合物对LoVo细胞表现出抗增殖活性，并对HT-29细胞产生合成致死效果，适用于研究DNA损伤反应(DDR)缺陷癌症。
T79121	ATR-IN-29	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	ATR-IN-29是一种口服活性的ATR激酶抑制剂，表现出抗增殖活性，其IC50为1 nM。
T63555	ATR-IN-6
	ATR-IN-6 是 ATR 的有效抑制剂。其中 ATR 是一种蛋白激酶，能够参与基因组稳定性和 DNA 损伤修复，是 PIKK 家族的成员。ATR-IN-6 对 ATR 激酶介导的疾病如增殖性疾病和癌症表现出研究潜力。
T79058	ATR-IN-24	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	ATR-IN-24（化合物1）为ATR抑制剂，具备抗肿瘤特性。
T61808	ATR-IN-14
	ATR-IN-14 (compound 1) is a powerful ATR kinase inhibitor that significantly inhibits ATR signaling pathways following CHKI protein phosphorylation, demonstrating a remarkable inhibition rate of 98.03% at 25 nM. Moreover, ATR-IN-14 exhibits notable anticancer efficacy in LoVo cells, displaying an IC50 value of 64 nM [1].
T63066	ATR-IN-13
	ATR-IN-13 是一种 ATR 激酶的有效抑制剂 (IC50: 2 nM)，能够用于研究 ATR 激酶介导的疾病 (如增生性疾病、癌症)。
T61587	ATR-IN-15
	ATR-IN-15 (compound 1) is a highly potent and orally active inhibitor of ATR kinase with an IC50 of 8 nM. Additionally, ATR-IN-15 demonstrates inhibitory activity against several targets, including human colon tumor cells LoVo, DNA-PK, and PI3K, with IC50 values of 47, 663, and 5131 nM, respectively [1].
T12225L	Nevanimibe hydrochloride PD-132301 hydrochloride,ATR101 hydrochloride	Apoptosis; Acyltransferase	Apoptosis; Metabolism
	Nevanimibe hydrochloride (PD-132301 hydrochloride) 是一种口服有效的，选择性酰基辅酶 A：胆固醇 O-酰基转移酶 1 抑制剂，EC50为 9 nM。它抑制 ACAT2，EC50为 368 nM。它诱导细胞凋亡，具有抗肾上腺皮质癌的潜力。
T79031	ATR-IN-21	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	ATR-IN-21（化合物60）是一种效力强大的ATR抑制剂，其IC50值小于1000 nM。
T62035	ATR-IN-7
	ATR-IN-7 是有效的ATR 抑制剂。
T61636	ATR-IN-19
	ATR-IN-19 (Compound 15 R-configure) 是一种ATR 抑制剂。
T63604	ATR-IN-18
	ATR-IN-18 是口服具有活力的 ATR 激酶抑制剂 (IC50: 0.69 nM)。ATR-IN-18 在 LoVo 细胞中表现出抗增殖效果 (IC50: 37.34 nM)。ATR-IN-18 显示出抗肿瘤作用。
T62563	ATR-IN-12
	ATR-IN-12 (Compound 5g) 是一种共济失调毛细血管扩张和 Rad3 相关 (ATR) 激酶的有效抑制剂 (IC50: 0.007 μM)。ATR-IN-12 能够明显降低 ATR 及其下游信号蛋白的磷酸化水平，具有良好的抗肿瘤效果。ATR-IN-12 是一种极有潜力的先导化合物，能够用于后续对 ATR 激酶的药物发现的研究。
T63923	ATR-IN-5
	ATR-IN-5 是 ATR 的有效抑制剂。其中 ATR 是 PIKK 家族的成员，是一类参与基因组稳定性和 DNA 损伤修复的蛋白激酶。ATR-IN-5 对 ATR 激酶介导的疾病如增殖性疾病和癌症表现出研究潜力。
T62233	ATR-IN-10
	ATR-IN-10 是一种有效的、高度选择性的 ATR 激酶的抑制剂 (IC50: 2.978μM)。
T62651	ATR-IN-11
	ATR-IN-11 (Compound Hit01) 是一种共济失调毛细血管扩张症和 Rad3 相关 (ATR) 激酶的有效抑制剂。ATR 激酶是 DNA 损伤反应 (DDR) 中的一个关键调节蛋白，负责感知复制压力 (RS)。ATR-IN-11 是一种有希望的先导化合物，能够用于发现后续针对 ATR 激酶的药物。 ATR-IN-11具有潜力进行癌症疾病的研究。
T61432	ATR-IN-16
	ATR-IN-16 (compound 46) is a highly effective ATR kinase inhibitor, exhibiting considerable anticancer activity in LoVo cells, as demonstrated by its IC 50 value of 410 nM [1].
T73301	ATR-IN-20
	ATR-IN-20是一种高效的ATR(ATM/ATR)抑制剂, IC50值仅为3 nM。该化合物还能抑制mTOR(IC50值为18 nM)，并展示出对PI3Kα(100 nM)、ATM(100 nM)和DNA-PK(662 nM)的良好选择性。ATR-IN-20具备优秀的药代动力学属性(F=30%)，同时显示了其抗癌潜力。
T79033	ATR-IN-22	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	ATR-IN-22 (Compound 34) 是口服活性ATR抑制剂，能够抑制MIAPaCa-2增殖，IC50值小于1 μM。此外，该化合物在结肠癌研究中展现出抗肿瘤活性。
T6612	NU6027	ATM/ATR; DNA-PK; CDK	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	NU6027 是一种有效的 ATR/CDK 抑制剂，抑制 CDK1/2、ATR 和 DNA-PK，Ki 为 2.5 μM/1.3 μM、0.4 μM 和 2.2 μM。它以 ATR 依赖性方式增强羟基脲和顺铂的细胞毒性。
T1821	CGK733 CGK 733	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	CGK733 (CGK 733) 是一种有效的选择性 ATM/ATR 抑制剂，用于癌症研究。
T5175	azd1390	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	AZD1390 是一种可口服的，可渗透脑的ATM 高度选择性抑制剂，IC50为 0.78 nM。
T1958	AZ20	ATM/ATR; mTOR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	AZ20 是一种有效且特异性的 ATR 激酶抑制剂，IC50值为 5 nM。它还抑制mTOR 活性，IC50值为 38 nM。
T4443	AZ32	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	AZ32 是一种口服生物利用度和血脑屏障穿透性 ATM 抑制剂，对 ATM 酶的 IC50 <6.2 nM，对细胞内 ATM 的 IC50 为 0.31 μM。
T6770	AZD0156	Apoptosis; ATM/ATR	Apoptosis; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	AZD0156 是一种口服活性 ATM 选择性抑制剂，IC50为 0.58 nM。它抑制 ATM 介导的信号转导，防止 DNA 损伤检查点激活，破坏 DNA 损伤修复，起抗肿瘤作用。
T3338	Ceralasertib AZD6738	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Ceralasertib (AZD6738) 是一种具有口服活性的选择性 ATR 激酶抑制剂，IC50 为 1 nM。
T6261	CP-466722 CP 466722,CP466722	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	CP-466722 是一种有效且可逆的 ATM 抑制剂，IC50值为 4.1 μM。它不会抑制细胞中的 ATR 和 PI3K 或 PIKK 家族成员。
T2084	ETP-46464	ATM/ATR; DNA-PK; PI3K; mTOR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	ETP-46464 是一种有效且特异性的 ATR 抑制剂，IC50为 25 nM。
T1923	BRD4770	Histone Methyltransferase	Chromatin/Epigenetic
	BRD4770 是组蛋白甲基转移酶G9a 抑制剂，可激活共济失调毛细血管扩张突变途径并诱导细胞衰老。它可抑制H3K9的二甲基和三甲基化，EC50为 5 µM。
T2685	KU-55933 ATM Kinase Inhibitor	ATM/ATR; DNA-PK; PI3K; mTOR; Autophagy	Autophagy; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	KU-55933 (ATM Kinase Inhibitor) 是一种 ATM 抑制剂，IC50和 Ki 值分别为 12.9 和 2.2 nM。它对 ATM 的选择性比对 PI3K/PI4K、 DNA-PK、ATR 和 mTOR 高。
T7318	Elimusertib BAY-1895344	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Elimusertib (BAY-1895344) 是一种可口服的选择性ATR 抑制剂，IC50值为 7 nM。它具有抗肿瘤活性，可研究实体瘤和淋巴瘤。
T7122	AZD-7648	DNA-PK	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	AZD-7648 是一种 DNA 依赖性蛋白激酶 (DNA-PK) 抑制剂，在酶试验中 IC50 为 0.63 nM，具有抗肿瘤活性。
T1395	Diatrizoic Acid Diatrizoate,泛影酸,Amidotrizoic acid	Apoptosis; Others	Apoptosis; Others
	Diatrizoic Acid (Amidotrizoic acid) 是一种有机碘化不透射线 X 射线造影剂，用于放射诊断，具有对气道进行放射照相成像的潜力。它通过钙失调诱导线粒体更新和氧化应激，激活细胞凋亡。
T39630	Zandatrigine NBI-921352,XEN901	Sodium Channel	Membrane transporter/Ion channel
	Zandatrigine (NBI-921352) 是钠通道蛋白 8 型亚基 α 的阻断剂，可用于癫痫治疗的神经系统病理学研究。
T76279	Retatrutide LY3437943	Glucagon Receptor	GPCR/G Protein
	Retatrutide (LY3437943) 是胰高血糖素受体、葡萄糖依赖性促胰岛素多肽受体和胰高血糖素样肽-1 受体三重激动剂,对GCGR、GIPR 和 GLP-1R 具有抑制作用。Retatrutide 可用研究肥胖症。
T1604	Tiratricol 3,3',5-Triiodothyroacetic acid,替拉曲可	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Tiratricol (3,3',5-Triiodothyroacetic acid) 是 T3 和 T4 甲状腺激素的代谢物；促进高脂血症、局部脂肪营养不良和肥胖。它已用于研究 Allan-Herndon-Dudley 综合征治疗的试验。
T76279L1	Retatrutide sodium salt Retatrutide sodium salt(2381089-83-2 free base),LY3437943 sodium salt	Glucagon Receptor	GPCR/G Protein
	Retatrutide sodium salt 是一种有效的胰高血糖素受体 (GCGR)、葡萄糖依赖性促胰岛素多肽受体 (GIPR) 和胰高血糖素样肽-1 受体 (GLP-1R) 的三重激动剂肽。Retatrutide sodium salt 可用于研究2型糖尿病和肥胖症。
T21250L	Matrixyl Acetate(214047-00-4 free base) Palmitoyl-KTTKS,Palmitoyl pentapeptide,Pal-Lys-Thr-Thr-Lys-Ser-OH,Matrixyl,五胜肽	Others	Others
	Matrixyl Acetate(214047-00-4 free base) (Palmitoyl pentapeptide) 是一种用于抗皱化妆品的 matrikine。
T0212	Seratrodast 塞曲司特,AA 2414,ABT-001	COX; Prostaglandin Receptor; PPAR	DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Seratrodast (ABT-001) 是一种血栓素 A2 受体 (TP) 拮抗剂，用于治疗哮喘。
T11326	Frovatriptan succinate hydrate Frovelan,夫罗曲坦琥珀酸盐水合物 ,Frova	5-HT Receptor	GPCR/G Protein; Neuroscience
	Frovatriptan succinate hydrate (Frova) 是一种有效、高亲和力、选择性和口服活性的 5-HT1B、HT1D 受体激动剂和中等有效的 5-HT7 受体激动剂，pKi 值分别为 8.6、8.4 和 6.7。它可有效治疗各种偏头痛，包括恶心、呕吐、畏光和畏声等相关症状。

化合物

Cat.No: T3032

Synonym: ATR Inhibitor IV

Target: ATM/ATR

Cat.No: T10406

Synonym: M1774,ATR inhibitor 1

Target: Apoptosis, ATM/ATR, Others, Chk

Cat.No: T62083

Synonym: ATR inhibitor 4,RP-3500

Target: ATM/ATR

Cat.No: T40212

Cat.No: T40077

Cat.No: T9321

Synonym: ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid

Target: Influenza Virus, MEK, Antibacterial

Cat.No: T10407

Synonym: ATR inhibitor 2

Target: ATM/ATR

Cat.No: T12225

Synonym: ATR-101,PD-132301

Target: Others

Cat.No: T62084

Cat.No: T62548

Cat.No: T78959

Target: ATM/ATR

Cat.No: T79121

Target: ATM/ATR

Cat.No: T63555

Cat.No: T79058

Target: ATM/ATR

Cat.No: T61808

Cat.No: T63066

Cat.No: T61587

Nevanimibe hydrochloride

Cat.No: T12225L

Synonym: PD-132301 hydrochloride,ATR101 hydrochloride

Target: Apoptosis, Acyltransferase

Cat.No: T79031

Target: ATM/ATR

Cat.No: T62035

Cat.No: T61636

Cat.No: T63604

Cat.No: T62563

Cat.No: T63923

Cat.No: T62233

Cat.No: T62651

Cat.No: T61432

Cat.No: T73301

Cat.No: T79033

Target: ATM/ATR

Cat.No: T6612

Target: ATM/ATR, DNA-PK, CDK

Cat.No: T1821

Synonym: CGK 733

Target: ATM/ATR

Cat.No: T5175

Target: ATM/ATR

Cat.No: T1958

Target: ATM/ATR, mTOR

Cat.No: T4443

Target: ATM/ATR

Cat.No: T6770

Target: Apoptosis, ATM/ATR

Cat.No: T3338

Synonym: AZD6738

Target: ATM/ATR

Cat.No: T6261

Synonym: CP 466722,CP466722

Target: ATM/ATR

Cat.No: T2084

Target: ATM/ATR, DNA-PK, PI3K, mTOR

Cat.No: T1923

Target: Histone Methyltransferase

Cat.No: T2685

Synonym: ATM Kinase Inhibitor

Target: ATM/ATR, DNA-PK, PI3K, mTOR, Autophagy

Cat.No: T7318

Synonym: BAY-1895344

Target: ATM/ATR

Cat.No: T7122

Target: DNA-PK

Diatrizoic Acid

Cat.No: T1395

Synonym: Diatrizoate,泛影酸,Amidotrizoic acid

Target: Apoptosis, Others

Cat.No: T39630

Synonym: NBI-921352,XEN901

Target: Sodium Channel

Cat.No: T76279

Synonym: LY3437943

Target: Glucagon Receptor

Cat.No: T1604

Synonym: 3,3',5-Triiodothyroacetic acid,替拉曲可

Target: Thyroid hormone receptor(THR)

Retatrutide sodium salt

Cat.No: T76279L1

Synonym: Retatrutide sodium salt(2381089-83-2 free base),LY3437943 sodium salt

Target: Glucagon Receptor

Matrixyl Acetate(214047-00-4 free base)

Cat.No: T21250L

Synonym: Palmitoyl-KTTKS,Palmitoyl pentapeptide,Pal-Lys-Thr-Thr-Lys-Ser-OH,Matrixyl,五胜肽

Target: Others

Cat.No: T0212

Synonym: 塞曲司特,AA 2414,ABT-001

Target: COX, Prostaglandin Receptor, PPAR

Frovatriptan succinate hydrate

Cat.No: T11326

Synonym: Frovelan,夫罗曲坦琥珀酸盐水合物 ,Frova

Target: 5-HT Receptor

Cat. No.	Product Name	Target	Signaling Pathways
TN1673	Garcinone C 伽升沃 C,伽升沃C	ATM/ATR; CDK; STAT; AChR; Antifection	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; JAK/STAT signaling; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
	Garcinone C 是一种从 Garcinia oblongifolia Champ 中提取的黄酮衍生物，具有抗炎、收敛和促进肉芽的活性。 Garcinone C 是一种 AChE 抑制剂，对某些癌症具有潜在的细胞毒性作用。
T3330	trans-Trimethoxyresveratrol trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	trans-Trimethoxyresveratrol (MR-3) 是一种 Resveratrol(RSV) 的衍生物，与Resveratrol(RSV)相比，它可能是一个更有效的抗炎、抗血管新生的化合物。
T3933	Jatrorrhizine Yatrorizine,neprotin,药根碱	MAO; 5-HT Receptor; Antibacterial; AChE	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱，具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
T2754	Oxymatrine Oxysophoridine,氧化苦参碱,Matrine N-oxide	Influenza Virus; Autophagy; TGF-beta/Smad	Autophagy; Microbiology/Virology; Stem Cells
	Oxymatrine (Oxysophoridine) 是来自槐属物种根部的一种生物碱，具有抗炎，抗纤维化和抗肿瘤的作用。它是一种用于治疗乙型肝炎病毒的中药。它可抑制博卡病毒 MVC 复制，降低病毒基因表达并减少病毒感染诱导的细胞凋亡。它还可以抑制 iNOS 的表达和 TGF-β/Smad 通路。
T3364	Veratramine NSC17821,黎芦碱,NSC23880,藜芦胺	Sodium Channel	Membrane transporter/Ion channel
	Veratramine (NSC-23880) 是一种信号转导抑制剂，可作用于肿瘤。
T5716	4'-Methoxyresveratrol 白藜芦醇-4'-甲醚,4'-O-Methylresveratrol	advanced glycation end products	Others
	4'-Methoxyresveratrol (4'-O-Methylresveratrol) 是一种多酚类化合物，来源于双翅目植物中，具有抗雄激素、抗真菌和抗炎症作用。它能抑制 RAGE- 介导的 MAPK/NF-κB 信号通路，并激活 NLRP3 炎性体，从而缓解 AGE- 诱导的炎症。
T3S1068	Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene	Tyrosinase; Autophagy; HSV	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Oxyresveratrol (trans-Oxyresveratrol) 是非竞争性酪氨酸酶抑制剂，对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1，HSV-2和水痘带状疱疹病毒，具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T5657	Veratraldehyde 3,4-Dimethoxybenzaldehyde,藜芦醛	Antifungal	Microbiology/Virology
	Veratraldehyde (3,4-Dimethoxybenzaldehyde) 是一种能够使用于香料，农业化学和制药工业中的重要化学品。
T6S1010	Allomatrine 槐定碱,别苦参碱	Others	Others
	Allomatrine 是一种来源槐花树皮的生物碱。它能够激活 κ-阿片受体，进而产生缓解疼痛的作用。
TN7036	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) 是一种从玛卡中分离得到的玛卡酰胺。它能够激活典型的Wnt/β‐catenin 信号通路，诱导间充质干细胞成骨分化和随后的骨形成，可用于研究骨质疏松症。
T3666	Atractylodin 苍术素,Atractydin	Lipid	Metabolism
	Atractylodin (Atractydin) 是一种Atractylodes lancea 和A. chinensis 的根茎中所含精油的活性成分。它是天然杀虫剂，能够抑制Tribolium castaneum 的活性。
TCS1372	Atraric acid	Phosphatase; Androgen Receptor	Endocrinology/Hormones; Metabolism
	Atraric acid 衍生物作为一种新的化学先导结构，用于作为 AR 拮抗剂的新型治疗化合物，可用于预防或治疗前列腺疾病。它以剂量依赖性方式抑制 PTP1B 活性，IC50 值为 51.5 uM，表明阿特拉酸具有治疗糖尿病的潜力。
T5S0168	Atractylenolide II 2-Atractylenolide,Asterolide,苍术内酯II	Apoptosis; ERK; p38 MAPK; Akt; STAT	Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Atractylenolide II (2-Atractylenolide) 是一种从白术干燥根茎分离的倍半萜类天然产物，具有抗增殖活性。
T124477	Resveratrol 4'-(6-galloylglucoside) Resveratrol-4'-O-(6"-galloyl)glucoside	Others	Others
	Resveratrol 4'-(6-galloylglucoside) (Resveratrol-4'-O-(6"-galloyl)glucoside)是一种天然产物，存在于植物掌叶大黄 rhubarb (Rheum palmatum L.)的根中。
TN1413	Atranorin 荔枝素，巴美灵,荔枝素	Endogenous Metabolite; NO Synthase; Ras	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism
	Atranorin 是地衣的次生代谢产物，具有显着的抗伤害、抗炎和氧化还原活性，对 H(2)O(2) 诱导的氧化应激下的细胞具有细胞保护作用。
T3840	Dihydroresveratrol 3,4',5-Trihydroxybibenzyl,二氢白藜芦醇,二氢藜芦醇	Estrogen Receptor/ERR; Others	Endocrinology/Hormones; Others
	Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) 是一种激素受体调节剂，是一种植物雌激素。它在皮摩尔和纳摩尔浓度下促进前列腺和乳腺癌细胞增殖。
T8170	Carboxyatractyloside 羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt	Others	Others
	Carboxyatractyloside (Carboxyatractyloside tripotassium salt) tripotassium salt 是一种 ADP/ATP 载体蛋白 (ADP/ATP carrier) 抑制剂，抑制线粒体 ADP/ATP 的转运。它是一种具有毒性的天然产物，
T4912	Jatrorrhizine chloride 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride	Others; 5-HT Receptor; OCT; Antibacterial; AChE	GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others
	Jatrorrhizine chloride (Neprotine chloride) 是从黄连中分离得到的生物碱，具有神经保护、抗菌、抗氧化和抗疟原虫活性。它通过抑制摄取2转运蛋白的活性减少血清素和去甲肾上腺素的摄取。它是具有口服活性的乙酰胆碱酯酶抑制剂。
T1558	Resveratrol 白藜芦醇,trans-Resveratrol,SRT 501	Apoptosis; Mitophagy; IκB/IKK; Lipoxygenase; Sirtuin; COX; NADPH; DNA/RNA Synthesis; Nrf2; Antibacterial; Antibiotic; Autophagy; Antifungal	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	Resveratrol (SRT 501) 属于多酚类天然产物，是一种植物抗毒素，具有抗氧化和化学预防活性。Resveratrol 的靶点广泛，包括 COX、SIRT、LOC 等。Resveratrol 可以诱导细胞自噬和凋亡。
TN3340	Acetylatractylodinol Tractylodinol acetate,乙酰基仓术呋喃烃醇	Others	Others
	Acetylatractylodinol (Tractylodinol acetate) 是分离自Atractylodes lancea 中，具有抗氧化作用。
TN1057	Veratrosine 藜芦托素,Veratramine 3-glycoside,Veratramine-beta-D-glucoside	Platelet aggregation	Others
	Veratrosine (Veratramine-beta-D-glucoside) 是一种从藜芦草本植物中分离出来的生物碱。 Veratrosine 对血小板聚集表现出微弱的抑制活性。
T2810	(20S)-Protopanaxatriol 原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT	Apoptosis; Estrogen Receptor/ERR; Glucocorticoid Receptor; Estrogen/progestogen Receptor; Liver X Receptor	Apoptosis; Endocrinology/Hormones; Metabolism
	(20S)-Protopanaxatriol (g-PPT) 是人参皂苷的代谢物，通过糖皮质激素受体和雌激素受体起作用，同时为LXRα的抑制剂，具有广泛的抗癌活性。
T0657	Veratryl alcohol 3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇	Others	Others
	Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) 是木质素降解真菌的次级代谢产物，通常作为非酚性底物测定木质素分解活性。
T2804	Panaxatriol 人参三醇,Panaxtriol	Others	Others
	Panaxatriol (Panaxtriol) 是一种能够减轻由于辐射损伤造成的骨髓抑制的天然产物。
T3744	Veratric acid Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species; COX	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Veratric acid (3,4-Dimethoxybenzoic acid) 是从蔬菜和水果中得到的一种可口服多酚，具有抗氧化、保护心血管和抗炎活性。当细胞受到 UVB 辐射时，它能够减少上调的 COX-2 表达，降低 PGE2 和 IL-6 水平。
T2870	Matrine Vegard,苦参碱,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy; Ferroptosis; Opioid Receptor; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Matrine (Vegard) 是一种从槐属植物中分离出来的生物碱，可作为一种κ阿片受体激动剂，有抗肿瘤活性。
T5668	Triacetylresveratrol 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol	BCL; NF-κB; STAT	Apoptosis; JAK/STAT signaling; NF-κB; Stem Cells
	Triacetylresveratrol (Acetyl-trans-resveratrol) 是 Resveratrol 的乙酰化类似物，可降低 STAT3和 NF-κB 磷酸化，具有抗癌作用。
T5S0167	Atractylenolide I 白术内酯 I,白术内酯I；苍术内酯I	IL Receptor; TNF; TLR; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Atractylenolide I 是从白术根中得到的一种倍半萜烯，具有神经保护、抗过敏、抗炎和抗癌等多种生物活性。它是一种TLR4拮抗剂，在 A375 细胞中，能够降低JAK2和STAT3的磷酸化水平。
T3902	Atractylenolide III 白术内酯 III,ICodonolactone,8β-Hydroxyasterolide	Apoptosis	Apoptosis
	Atractylenolide III (ICodonolactone) 是白术根茎主要成分，通过诱导细胞色素 c 的释放、上调 Bax 的表达和易位凋亡诱导因子，是治疗人肺癌的潜力。
TN1640	Fabiatrin	Others	Others
	Fabiatrin 是从 Przewalskia tangutica 的正丁醇提取物中分离和鉴定的天然产物。
T3917	Protopanaxatriol 20(R)-APPT,20(R)-Protopanaxatriol,原人参三醇,(20R)-Protopanaxatriol	PPAR	DNA Damage/DNA Repair; Metabolism
	Protopanaxatriol (20(R)-APPT) 是天然的人参皂苷的糖苷配基，包括 Re，Rf，Rg1，Rg2 和 Rh。
T2986	Jatrorrhizine hydrochloride	Others	Others
	Jatrorrhizine hydrochloride 是从小檗、根中提取的。
T3791	Atractyloside A	AChR	Neuroscience
	Atractyloside A 是存在于一些植物中的贝壳杉类二萜糖苷，具有降血压、降血糖、抗肿瘤等活性。
T3S0156	Atractyloside potassium salt Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐	Others	Others
	Atractyloside potassium salt (Atractyloside Dipotassium Salt) 是一种从苍术果实中分离出得到的二萜苷类化合物，具有毒性。它能抑制大鼠心脏线粒体膜的氯离子通道。它是高效、特异性的线粒体 ADP/ATP 转运 (ADP/ATP transport) 抑制剂。
TN5101	Tasumatrol L	Others	Others
	Tasumatrol L is a natural product from Taxus sumatrana.
TN3304	8beta-Methoxyatractylenolide I	Others	Others
	8beta-Methoxyatractylenolide I is a natural product from Atractylodes macrocephala.
TN2997	4(15),5,10(14)-Germacratrien-1-ol	Others	Others
	4(15),5,10(14)-Germacratrien-1-ol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2997，CAS号为 81968-62-9。
TN5666	1,4,6-Heptatrien-3-one Bisdemethoxycurcumin,BDMC,二脱甲氧基姜黄素
	1,4,6-Heptatrien-3-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5666，CAS号为 52328-96-8。
TN1810	Jatropholone B	Others	Others
	Jatropholone B shows antiproliferative activity against cancer cell lines. It also has gastroprotective activity in preventing the gastric lesions in mice.
T81008	Tetrahydropalmatrubine
	Tetrahydropalmatrubine为从Corydalis saxicola草本植物中提取的生物碱。
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to inhibit growth and metastasis of brea
TN2827	25(S)-Hydroxyprotopanaxatriol	Others	Others
	25(S)-Hydroxyprotopanaxatriol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2827，CAS号为 113539-03-0。
TN2612	13-Hydroxy-8,11,13-podocarpatrien-18-oic acid	Others	Others
	13-Hydroxy-8,11,13-podocarpatrien-18-oic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2612，CAS号为 61597-83-9。
T73949	Isatropolone A
	Isatropolone A，一种含有1,5-二酮部分的天然产物，源自链霉菌Gö66。该化合物在抑制利什曼原虫(Leishmaniadonovani)方面表现出良好的活性，IC50值为0.5 μM。
TN3370	Albatrelin C	Others	Others
	Albatrelin C is a natural product from Albatrellus ovinus.
TN5725	Juncatrin A 1-(3,7-Dihydroxy-2,8-dimethyl-9,10-dihydrophenanthren-1-yl)ethanone
	Juncatrin A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5725，CAS号为 2265925-12-8。
T3S0165	Atractylone Atractylon,苍术酮	Others	Others
	Atractylone (Atractylon) 具有保肝、降血糖、抗菌、抗肿瘤、抗病毒等作用。
TN2728	Jatrophane 4	Antifection	Microbiology/Virology
	Jatrophane 3 (2R,3R, 4S,5R,7S,8S,9S,l3S,14S,15R)-2,5,14-triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxy-9-nicotinoyloxyjatropha-6(17),11E-diene) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), with an EC50 value of 0.43 ug/cm2.
TN5138	Teuclatriol	TNF; NF-κB; TLR	Apoptosis; Immunology/Inflammation; NF-κB
	Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-ÎºB signaling at doses of 312µM and higher. It showed a significant anti-proliferative effect on human activated-peripheral blood lymphocytes (IC50, 72.8 ± 5.4 µg/ml).
TN5370	1β,10β-Epoxydesacetoxymatricarin
	1beta,10beta-Epoxydesacetoxymatricarin shows high anti-hypercholesterolemic potential.
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天然产物

Cat.No: TN1673

Synonym: 伽升沃 C,伽升沃C

Target: ATM/ATR, CDK, STAT, AChR, Antifection

trans-Trimethoxyresveratrol

Cat.No: T3330

Synonym: trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene

Target: Reactive Oxygen Species

Cat.No: T3933

Synonym: Yatrorizine,neprotin,药根碱

Target: MAO, 5-HT Receptor, Antibacterial, AChE

Cat.No: T2754

Synonym: Oxysophoridine,氧化苦参碱,Matrine N-oxide

Target: Influenza Virus, Autophagy, TGF-beta/Smad

Cat.No: T3364

Synonym: NSC17821,黎芦碱,NSC23880,藜芦胺

Target: Sodium Channel

4'-Methoxyresveratrol

Cat.No: T5716

Synonym: 白藜芦醇-4'-甲醚,4'-O-Methylresveratrol

Target: advanced glycation end products

Cat.No: T3S1068

Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene

Target: Tyrosinase, Autophagy, HSV

Cat.No: T5657

Synonym: 3,4-Dimethoxybenzaldehyde,藜芦醛

Target: Antifungal

Cat.No: T6S1010

Synonym: 槐定碱,别苦参碱

Target: Others

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

Cat.No: TN7036

Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14

Target: Wnt/beta-catenin

Cat.No: T3666

Synonym: 苍术素,Atractydin

Target: Lipid

Cat.No: TCS1372

Target: Phosphatase, Androgen Receptor

Atractylenolide II

Cat.No: T5S0168

Synonym: 2-Atractylenolide,Asterolide,苍术内酯II

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

Resveratrol 4'-(6-galloylglucoside)

Cat.No: T124477

Synonym: Resveratrol-4'-O-(6"-galloyl)glucoside

Target: Others

Cat.No: TN1413

Synonym: 荔枝素，巴美灵,荔枝素

Target: Endogenous Metabolite, NO Synthase, Ras

Dihydroresveratrol

Cat.No: T3840

Synonym: 3,4',5-Trihydroxybibenzyl,二氢白藜芦醇,二氢藜芦醇

Target: Estrogen Receptor/ERR, Others

Carboxyatractyloside

Cat.No: T8170

Synonym: 羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt

Target: Others

Jatrorrhizine chloride

Cat.No: T4912

Synonym: 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride

Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE

Cat.No: T1558

Synonym: 白藜芦醇,trans-Resveratrol,SRT 501

Target: Apoptosis, Mitophagy, IκB/IKK, Lipoxygenase, Sirtuin, COX, NADPH, DNA/RNA Synthesis, Nrf2, Antibacterial, Antibiotic, Autophagy, Antifungal

Acetylatractylodinol

Cat.No: TN3340

Synonym: Tractylodinol acetate,乙酰基仓术呋喃烃醇

Target: Others

Cat.No: TN1057

Synonym: 藜芦托素,Veratramine 3-glycoside,Veratramine-beta-D-glucoside

Target: Platelet aggregation

(20S)-Protopanaxatriol

Cat.No: T2810

Synonym: 原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT

Target: Apoptosis, Estrogen Receptor/ERR, Glucocorticoid Receptor, Estrogen/progestogen Receptor, Liver X Receptor

Veratryl alcohol

Cat.No: T0657

Synonym: 3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇

Target: Others

Cat.No: T2804

Synonym: 人参三醇,Panaxtriol

Target: Others

Cat.No: T3744

Synonym: Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid

Target: Reactive Oxygen Species, COX

Cat.No: T2870

Synonym: Vegard,苦参碱,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine

Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy

Triacetylresveratrol

Cat.No: T5668

Synonym: 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol

Target: BCL, NF-κB, STAT

Atractylenolide I

Cat.No: T5S0167

Synonym: 白术内酯 I,白术内酯I；苍术内酯I

Target: IL Receptor, TNF, TLR, JAK, STAT

Atractylenolide III

Cat.No: T3902

Synonym: 白术内酯 III,ICodonolactone,8β-Hydroxyasterolide

Target: Apoptosis

Cat.No: TN1640

Target: Others

Protopanaxatriol

Cat.No: T3917

Synonym: 20(R)-APPT,20(R)-Protopanaxatriol,原人参三醇,(20R)-Protopanaxatriol

Target: PPAR

Jatrorrhizine hydrochloride

Cat.No: T2986

Target: Others

Atractyloside A

Cat.No: T3791

Target: AChR

Atractyloside potassium salt

Cat.No: T3S0156

Synonym: Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐

Target: Others

Cat.No: TN5101

Target: Others

8beta-Methoxyatractylenolide I

Cat.No: TN3304

Target: Others

4(15),5,10(14)-Germacratrien-1-ol

Cat.No: TN2997

Target: Others

1,4,6-Heptatrien-3-one

Cat.No: TN5666

Synonym: Bisdemethoxycurcumin,BDMC,二脱甲氧基姜黄素

Cat.No: TN1810

Target: Others

Tetrahydropalmatrubine

Cat.No: T81008

Cudratricusxanthone A

Cat.No: TN5901

25(S)-Hydroxyprotopanaxatriol

Cat.No: TN2827

Target: Others

13-Hydroxy-8,11,13-podocarpatrien-18-oic acid

Cat.No: TN2612

Target: Others

Cat.No: T73949

Cat.No: TN3370

Target: Others

Cat.No: TN5725

Synonym: 1-(3,7-Dihydroxy-2,8-dimethyl-9,10-dihydrophenanthren-1-yl)ethanone

Cat.No: T3S0165

Synonym: Atractylon,苍术酮

Target: Others

Cat.No: TN2728

Target: Antifection

Cat.No: TN5138

Target: TNF, NF-κB, TLR

1β,10β-Epoxydesacetoxymatricarin

Cat.No: TN5370

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02953	TEM8/ANTXR1 Protein, Human, Recombinant (hFc) ATR,TEM8,anthrax toxin receptor 1,GAPO	Human	HEK293 Cells
	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro...
TMPJ-01333	TEM8/ANTXR1 Protein, Human, Recombinant (His) ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax ...	Human	HEK293 Cells
	Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ...
TMPY-02286	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His) cholinergic receptor, muscarinic 1	H1N1	E. coli
	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.3 kDa and the accession number is B4UPA8.
TMPY-00065	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) Matrix protein VP40	EBOV	E. coli
	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.4 kDa and the accession number is B8XCM9.
TMPH-01673	Human metapneumovirus (strain CAN97-83) Matrix protein (His)	HMPV	P. pastoris (Yeast)
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
TMPH-03036	Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc) Cardiotoxin 2,CTX A2,Cardiotoxin 1A,Cardiotoxin A2,Cardiotox...	Naja atra	E. coli
	Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities, but 2-fold less important than that of CTX-A4. It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity. It may interact with sulfatides in the cell membrane which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induce mitochondrial swelling and fragmentation.
TMPY-00281	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP)	EBOV	E. coli
	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 79.1 kDa and the accession number is B0LPL6.
TMPH-02347	Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His)	H1N1	E. coli
	Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins ...
TMPH-03225	Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)	RABV	E. coli
	Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa an...
TMPH-03228	Rabies virus (RABV) (strain SAD B19) Matrix Protein (His)	RABV	E. coli
	Rabies virus (RABV) (strain SAD B19) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P16285.
TMPH-00450	SVSP Protein, Crotalus atrox, Recombinant (His)	Crotalus atrox	P. pastoris (Yeast)
	SVSP Protein, Crotalus atrox, Recombinant (His) is expressed in Yeast.
TMPH-01426	HEATR6 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	HEATR6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03226	Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)	RABV	E. coli
	Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.9 kDa and the accessio...
TMPY-00216	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.5 kDa and the accession number is B0LPL6.
TMPY-00284	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 78.7 kDa and the accession number is X5H596.
TMPH-00449	Phospholipase A2 Protein, Crotalus atrox, Recombinant (His & Myc)	Crotalus atrox	Baculovirus Insect Cells
	Phospholipase A2 Protein, Crotalus atrox, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-03693	VSIV (strain Glasgow) Matrix Protein (His)	VSIV	E. coli
	VSIV (strain Glasgow) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.8 kDa and the accession number is P04876.
TMPH-01672	Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)	HMPV	E. coli
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
TMPH-01643	Matrilin-3/MATN3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.
TMPH-03227	Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His)	RABV	E. coli
	Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P15197.
TMPH-03695	VSIV (strain 98COE North America) Matrix Protein (His & Myc)	VSIV	E. coli
	VSIV (strain 98COE North America) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.5 kDa and the accession number is Q8B0I2.
TMPY-03844	Influenza A H7N9 (A/Anhui/1/2013) Matrix protein 1/M1 Protein (His) cholinergic receptor, muscarinic 1	H7N9	E. coli
	Influenza A H7N9 (A/Anhui/1/2013) Matrix protein 1/M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.5 kDa.
TMPY-00064	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.1 kDa and the accession number is X5H596.
TMPY-00496	Influenza A H1N1 (A/Brevig Mission/1/1918) Matrix protein 1/M1 Protein (His) cholinergic receptor, muscarinic 1	H1N1	E. coli
	Influenza A H1N1 (A/Brevig Mission/1/1918) Matrix protein 1/M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is Q8BAC3.1.
TMPH-02346	Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc)	H1N1	E. coli
	Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. For...
TMPH-03694	VSIV (strain Glasgow) Matrix Protein (His & Myc)	VSIV	Baculovirus Insect Cells
	VSIV (strain Glasgow) Matrix Protein (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 30.7 kDa and the accession number is P04876.
TMPY-00498	Influenza A H3N2 (A/Aichi/2/1968) Matrix protein 1/M1 Protein (His) cholinergic receptor, muscarinic 1	H3N2	E. coli
	Influenza A H3N2 (A/Aichi/2/1968) Matrix protein 1/M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is I6SGW5.
TMPH-02348	Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)	H1N1	E. coli
	Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins ...
TMPH-02382	Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO)	MARV	E. coli
	Plays an essential role virus particle assembly and budding. Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 facilitates virus budding. The interaction with the nucleocapsid and the plasma membrane may also facilitate virus budding. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. May play a role in genome replication.
TMPH-00214	SVMP Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	SVMP Protein, Bothrops atrox, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.4 kDa and the accession number is P85420.
TMPH-00451	SVSP Protein, Crotalus atrox, Recombinant (His & Myc)	Crotalus atrox	Baculovirus Insect Cells
	Snake venom serine protease that may act in the hemostasis system of the prey. SVSP Protein, Crotalus atrox, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 29.1 kDa and the accession number is Q8QHK2.
TMPH-03692	VSIV (strain San Juan) Matrix Protein (His & Myc)	VSIV	E. coli
	VSIV (strain San Juan) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.5 kDa and the accession number is P03519.
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) Platelet aggregation activation inhibitor,Disintegrin colomb...	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Also inhibits T24 and SK-Mel-28 cell adhesion to fibronectin with IC(50) of 4.4 uM and 33 nM, respectively. Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted...
TMPY-03976	EEF1E1 Protein, Human, Recombinant (His) eukaryotic translation elongation factor 1 ε 1,P18,eukaryoti...	Human	E. coli
	EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. It is comprised of a bifunctional glutamyl-prolyl-tRNA synthase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl and aspartyl-tRNA synthases, and three auxiliary proteins, EEF1E1/p18, AIMP2/p38 and AIMP1/p43. EEF1E1 also plays a positive role in ATM/AT...
TMPJ-00870	NCK1 Protein, Human, Recombinant (His) SH2/SH3 Adaptor Protein NCK-α,SH2/SH3 Adaptor Protein NCK-Al...	Human	E. coli
	Cytoplasmic Protein NCK1 (NCK1) is a cytoplasmic protein that contains one SH2 domain and three SH3 domains. NCK1 is a member of the adapter family, which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. NCK1 maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. NCK1 plays a role in the DNA damage response, but not in the detection of the damage by ATM/ATR. It is also involved in transducing...
TMPY-02228	p53 Protein, Cynomolgus, Recombinant tumor protein p53,p53,TP53	Cynomolgus	E. coli
	p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 (TP53) is a transcription factor whose protein levels and post-translational modification state alter in response to cellular stress (such as DNA damag...

重组蛋白

TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02953

Species: Human

Expression System: HEK293 Cells

TEM8/ANTXR1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01333

Species: Human

Expression System: HEK293 Cells

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His)

Cat.No: TMPY-02286

Species: H1N1

Expression System: E. coli

Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His)

Cat.No: TMPY-00065

Species: EBOV

Expression System: E. coli

Human metapneumovirus (strain CAN97-83) Matrix protein (His)

Cat.No: TMPH-01673

Species: HMPV

Expression System: P. pastoris (Yeast)

Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)

Cat.No: TMPH-03036

Species: Naja atra

Expression System: E. coli

Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP)

Cat.No: TMPY-00281

Species: EBOV

Expression System: E. coli

Influenza A H1N1 (strain A/USA:Phila/1935) Matrix protein 2 (His)

Cat.No: TMPH-02347

Species: H1N1

Expression System: E. coli

Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)

Cat.No: TMPH-03225

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain SAD B19) Matrix Protein (His)

Cat.No: TMPH-03228

Species: RABV

Expression System: E. coli

SVSP Protein, Crotalus atrox, Recombinant (His)

Cat.No: TMPH-00450

Species: Crotalus atrox

Expression System: P. pastoris (Yeast)

HEATR6 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01426

Species: Human

Expression System: E. coli

Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)

Cat.No: TMPH-03226

Species: RABV

Expression System: E. coli

Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His)

Cat.No: TMPY-00216

Species: EBOV

Expression System: E. coli

Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP)

Cat.No: TMPY-00284

Species: EBOV

Expression System: E. coli

Phospholipase A2 Protein, Crotalus atrox, Recombinant (His & Myc)

Cat.No: TMPH-00449

Species: Crotalus atrox

Expression System: Baculovirus Insect Cells

VSIV (strain Glasgow) Matrix Protein (His)

Cat.No: TMPH-03693

Species: VSIV

Expression System: E. coli

Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)

Cat.No: TMPH-01672

Species: HMPV

Expression System: E. coli

Matrilin-3/MATN3 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01643

Species: Human

Expression System: E. coli

Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His)

Cat.No: TMPH-03227

Species: RABV

Expression System: E. coli

VSIV (strain 98COE North America) Matrix Protein (His & Myc)

Cat.No: TMPH-03695

Species: VSIV

Expression System: E. coli

Influenza A H7N9 (A/Anhui/1/2013) Matrix protein 1/M1 Protein (His)

Cat.No: TMPY-03844

Species: H7N9

Expression System: E. coli

Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His)

Cat.No: TMPY-00064

Species: EBOV

Expression System: E. coli

Influenza A H1N1 (A/Brevig Mission/1/1918) Matrix protein 1/M1 Protein (His)

Cat.No: TMPY-00496

Species: H1N1

Expression System: E. coli

Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc)

Cat.No: TMPH-02346

Species: H1N1

Expression System: E. coli

VSIV (strain Glasgow) Matrix Protein (His & Myc)

Cat.No: TMPH-03694

Species: VSIV

Expression System: Baculovirus Insect Cells

Influenza A H3N2 (A/Aichi/2/1968) Matrix protein 1/M1 Protein (His)

Cat.No: TMPY-00498

Species: H3N2

Expression System: E. coli

Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)

Cat.No: TMPH-02348

Species: H1N1

Expression System: E. coli

Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO)

Cat.No: TMPH-02382

Species: MARV

Expression System: E. coli

SVMP Protein, Bothrops atrox, Recombinant (His & Myc)

Cat.No: TMPH-00214

Species: Bothrops atrox

Expression System: E. coli

SVSP Protein, Crotalus atrox, Recombinant (His & Myc)

Cat.No: TMPH-00451

Species: Crotalus atrox

Expression System: Baculovirus Insect Cells

VSIV (strain San Juan) Matrix Protein (His & Myc)

Cat.No: TMPH-03692

Species: VSIV

Expression System: E. coli

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

Cat.No: TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

EEF1E1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03976

Species: Human

Expression System: E. coli

NCK1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00870

Species: Human

Expression System: E. coli

p53 Protein, Cynomolgus, Recombinant

Cat.No: TMPY-02228

Species: Cynomolgus

Expression System: E. coli

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