72
61
18
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6652 |
Salbutamol hemisulfate
Ventolin Sulfate,沙丁胺醇半硫酸盐,Albuterol,Salbutamol Sulfate,硫酸沙丁胺醇,Bronchospray,Albuterol Sulfate |
Adrenergic Receptor; Autophagy | Autophagy; GPCR/G Protein; Neuroscience |
Salbutamol hemisulfate (Albuterol Sulfate) 是一种短效的β2肾上腺素受体激动剂,IC50 为 8.93 μM。 | |||
T9331 |
Bemnifosbuvir hemisulfate
AT-527 |
HCV Protease; SARS-CoV | Microbiology/Virology; Proteases/Proteasome |
Bemnifosbuvir hemisulfate (AT-527) 是一种 HCV 病毒复制抑制剂。 | |||
T0438 |
Proflavine Hemisulfate
3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate,硫酸原黄素 |
Others; Potassium Channel; DNA; Thrombin; Antibacterial; Autophagy | Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Others; Proteases/Proteasome |
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) 是一种 DNA 嵌入剂,也是一种吖啶染料。它是抗菌剂,也可作为 Kir3.2孔阻滞剂,可研究与 Kir3.2 相关的神经系统疾病。 | |||
T0494 |
Tetramisole hydrochloride
盐酸四咪唑,R-829,DL-Tetramisole hydrochloride,(±)-Tetramisole hydrochloride,Tetramisole HCl |
Phosphatase; Dehydrogenase; Antibiotic; Parasite | Metabolism; Microbiology/Virology |
Tetramisole hydrochloride (Tetramisole HCl) 抑制碱性磷酸酶, 是一种高纯度抗寄生虫药。 | |||
T61107 |
Tilomisole
Wy 18251 |
Others | Others |
Tilomisole (Wy 18251) 是一种可口服的苯并咪唑噻唑,具有抗炎活性和免疫调节活性。Tilomisole 可用于研究癌症和炎症。 | |||
T7942 |
Tranylcypromine hemisulfate
Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐 |
Histone Demethylase; MAO; Monoamine Oxidase | Chromatin/Epigenetic; Metabolism; Neuroscience |
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂,可用于研究抑郁症和子宫内膜异位症。 | |||
T14324 |
Artemisone
BAY 44-9585,Artemifone,青蒿酮 |
Others; Parasite | Microbiology/Virology; Others |
Artemisone (BAY 44-9585) 是一种半合成的有效抗疟疾剂,还是一种人CMV 的有效抑制剂,可抑制多种P. falciparum,平均IC50值为 0.83 nM。 | |||
T67509 |
Cholesteryl Hemisuccinate
Cholesterol hydrogen succinate |
Apoptosis; DNA/RNA Synthesis; Topoisomerase | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) 是一种经常使用在极性溶液中具有高溶解度的胆固醇类似物 ,具有保肝、抗癌和抑制肿瘤生长的作用。Cholesteryl Hemisuccinate 抑制对乙酰氨基酚 的肝毒性,并防止 AAP 诱导的肝细胞凋亡 和坏死 。Cholesteryl Hemisuccinate 抑制 DNA 聚合酶 和 DNA 拓扑异构酶 ,从而抑制 DNA 复制和修复以及细胞分裂。 | |||
T10305 |
Amiselimod hydrochloride
MT-1303 hydrochloride |
S1P Receptor; LPL Receptor | GPCR/G Protein |
Amiselimod hydrochloride (MT-1303 hydrochloride) 是一种鞘氨醇 1-磷酸受体 1 (S1P1) 调节剂。 | |||
T7165 |
Basmisanil
RG1662,RO5186582,巴米沙尼 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Basmisanil (RG1662) 是高度选择性GABAAα5负调节剂,用于治疗与唐氏综合症相关的认知障碍。 | |||
T28437 |
Pomisartan
BIBR-363,BIBR 363,BIBR363 |
RAAS | Endocrinology/Hormones |
Pomisartan (BIBR-363) 是一种小分子血管紧张素 1 型受体(AT1R)拮抗剂,可用于治疗心血管疾病,研究心脏衰竭和高血压。 | |||
T9604 |
beta-Estradiol 17-hemisuccinate
|
Estrogen Receptor/ERR | Endocrinology/Hormones |
beta-Estradiol 17-hemisuccinate 选择性染色富含雌激素受体 (ER) 的细胞。 | |||
T21899 |
Misonidazole
SR-1354,SR1354,Ro 7-0582 |
GPX | oxidation-reduction |
Misonidazole 是一种缺氧肿瘤细胞放射增敏剂,具有抗菌活性。 | |||
T4602 |
Hydrocortisone hemisuccinate
Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate |
Glucocorticoid Receptor; Others; Interleukin | Endocrinology/Hormones; Immunology/Inflammation; Others |
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素, 是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性,可用于研究溃疡性结肠炎。 | |||
T0294 |
6α-Methylprednisolone 21-hemisuccinate sodium salt
Asmacortone,Methylprodnisolone Sodium Succinate,甲强龙琥珀酸钠,Metypresol,Methylprednisolone sodium succinate,Corticel,6-Methylprednisolone succinate sodium |
Glucocorticoid Receptor; Glucagon Receptor | Endocrinology/Hormones; GPCR/G Protein |
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone) 是一种糖皮质激素,是一种有效的抗炎剂,半衰期比 Prednisolone 长。 | |||
T26308 |
Lipoxamycin hemisulfate
Lipoxamycin, sulfate (2:1),U-26146D,U26146D,U 26146D,Lipoxamycin |
Antifungal | Microbiology/Virology |
Lipoxamycin hemisulfate (Lipoxamycin) 是一种丝氨酸棕榈酰转移酶抑制剂 (IC50 = 21 nM),具有抗真菌活性。 | |||
T26375 |
(S)-Amisulpride
Esamisulpride,(S) Amisulpride,SEP-4199,(S)-氨磺必利 |
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
(S)-Amisulpride ((S) Amisulpride) 是一种有效的多巴胺D2/D3受体拮抗剂,具有抗精神和抗抑郁作用。它是5-HT7受体的拮抗剂,KI 值为 900 nM。 | |||
TF0106 |
Cholesteryl Hemisuccinate Tris Salt
|
Apoptosis | Apoptosis |
Cholesteryl Hemisuccinate Tris Salt 是一种具有保肝和抗癌活性的酸性胆固醇酯,是一种含有柴胡皂苷-d的二棕榈酰磷脂酰胆碱脂质体中的膜稳定剂,可增强顺铂的抗癌功效。Cholesteryl hemisuccinate 具有抗肿瘤活性,抑制肿瘤生长,抑制对乙酰氨基酚 (AAP) 的肝毒性,预防 AAP 诱导的肝细胞凋亡。Cholesteryl hemisuccinate 可保护啮齿动物免受对乙酰氨基酚、阿霉素、四氯化碳、氯仿和半乳糖胺的毒性作用。 | |||
T7887 |
8-Hydroxyquinoline hemisulfate
8-羟基喹啉硫酸盐,Oxyquinoline sulfate |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
8-Hydroxyquinoline hemisulfate (Oxyquinoline sulfate) 是一种单质子双齿螯合剂,具有温和的抑菌、驱虫和杀螨作用。 | |||
T77507 |
(-)-Benzotetramisole
|
||
(-)-Benzotetramisole 使一种高效且具有选择性的催化剂。(-)-Benzotetramisole 是抗蠕虫化合物四咪唑3 的苯annulated 衍生物,本身也是转化的有效催化剂。 | |||
T6353 |
(-)-p-Bromotetramisole Oxalate
(-)-对溴四咪唑草酸盐,L-p-Bromotetramisole oxalate,6-Bromolevamisole oxalate,(-)-p-Bromolevamisole oxalate |
Phosphatase; Phosphorylase | Metabolism |
(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) 是一种强效的、非特异性碱性磷酸酶抑制剂。 | |||
T6157 |
Devimistat
CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid |
Apoptosis; Dehydrogenase; Mitochondrial Metabolism | Apoptosis; Metabolism |
Devimistat (6,8-Bis(benzylthio)octanoic acid) 是一种线粒体代谢抑制剂,还是一种lipoic acid 拮抗剂,能阻断线粒体能量代谢,诱导多种癌细胞凋亡。 | |||
T1570 |
Telmisartan
BIBR 277,替米沙坦 |
RAAS; Autophagy | Autophagy; Endocrinology/Hormones |
Telmisartan (BIBR 277) 是一种血管紧张素II 1型受体拮抗剂,能够抑制其活性,IC50值为 9.2 nM。 | |||
T0227 |
Bromisoval
2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,溴米那,BRN 1773255,Bromovalerylurea,溴米索伐,Bromaral |
Others | Others |
Bromisoval (Isobromyl) 具有抗炎活性。 | |||
T0944 |
Levamisole hydrochloride
(-)-Tetramisole hydrochloride,盐酸左旋咪唑 |
Phospholipase; AChR; Parasite; HSV | Metabolism; Microbiology/Virology; Neuroscience |
Levamisole hydrochloride ((-)-Tetramisole hydrochloride) 是驱虫剂和免疫调节剂。它对HSV 病毒有明显抗病毒作用。 | |||
T21967 |
MEG hemisulfate
Mercaptoethylguanidine hemisulfate |
NOS | Immunology/Inflammation |
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) 是一种有效和选择性的诱导型 NO 合酶 (iNOS) 的抑制剂,在组织匀浆中抑制 iNOS,ecNOS 和 bNOS 的 EC50 值分别为 11.5,110 和 60 μM。MEG hemisulfate 也有效的过氧亚硝酸盐清除剂,可抑制过氧亚硝酸盐诱导的氧化过程。MEG hemisulfate 在许多炎症实验模型中具有保护作用,包括缺血/再灌注损伤,牙周炎,失血性休克,炎性肠病以及内毒素和败血性休克。 | |||
T0811 |
Amisulpride
DAN 2163,氨磺必利,阿米舒必利 |
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
Amisulpride (DAN 2163) 是多巴胺D2/D3受体拮抗剂,对于人多巴胺D2和D3的Ki 分别为 2.8 和 3.2 nM。 | |||
T33836L |
Oxamisole TFA
Oxamisole TFA(99258-56-7 Free base) |
Antiviral | Immunology/Inflammation |
Oxamisole TFA 是一种可口服且具有选择性的 T 细胞免疫调节剂,可用于研究病毒感染。 | |||
T28437L |
Pomisartan 2HCl
Pomisartan 2HCl(144702-17-0 Free base),BIBR363 2HCL |
RAAS | Endocrinology/Hormones |
Pomisartan 2HCl(BIBR363 2HCl)是一种小分子AT1R拮抗剂,用于研究心力衰竭和高血压。 | |||
T0277 |
Metaproterenol hemisulfate
Orciprenaline sulfate,Metaproterenol Sulfate,硫酸奥西那林 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Metaproterenol hemisulfate (Orciprenaline sulfate) 是一种 β2-肾上腺素能受体 (β2AR) 激动剂(IC50=68 nM),是一种直接作用的拟交感神经药,具有抗炎活性。 | |||
T69224 | Hemisurfen | ||
Hemisurfen is a small molecule, surfen derivative with heparan sulfate antagonist properties. | |||
T124866 | Pyrochamissanthin | ||
Pyrochamissanthin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124866。 | |||
T7348 |
Imisopasem manganese
M40403,伊米帕锰 |
Others | Others |
Imisopasem manganese (M40403) is a manganese superoxide MnSOD non-peptidyl mimetic. | |||
T31825 |
Fluoromisonidazole
|
||
Fluoromisonidazole, a Radiation-Sensitizing Agent, can be used for imaging tumor hypoxia: imaging the microenvironment for personalized cancer therapy. | |||
T12047 |
Misoprostol acid
|
Others | Others |
Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers. | |||
T61740 |
Esomeprazole hemistrontium
|
||
Esomeprazole hemistrontium, also known as (S)-Omeprazole, is a potent and orally active proton pump inhibitor that effectively reduces acid secretion by inhibiting the H+, K+-ATPase in gastric parietal cells. This compound exhibits promising potential for research in symptomatic gastroesophageal reflux disease [1] [2] [3]. | |||
T74219 |
Maximiscin
|
||
Maximiscin 是一种真菌代谢产物,可诱导DNA damage 损伤,并对一种三阴性乳腺癌亚型显示出选择性的细胞毒活性。 | |||
T27570 |
Ianthelliformisamine B TFA
Ianthelliformisamine-B TFA,IanthelliformisamineB TFA,Ianthelliformisamine B TFA salt |
||
Ianthelliformisamine B TFA, an antibiotic enhancer, is used to against resistant Gram-negative bacteria. | |||
T124224 |
Angeloylgomisin P
|
||
Angeloylgomisin P 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124224,CAS号为 77881-08-4。 | |||
T124658 |
Phlomisionoside
|
||
Phlomisionoside 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124658,CAS号为 558451-77-7。 | |||
T70595 |
Artemisinin B
|
||
Artemisinin B is a drug which may improve spatial memory in dementia patients and alter the levels of inflammatory cytokines in the hippocampus and the cortex. Artemisinin B may inhibit neuroinflammation and exert neuroprotective effects on cognitive functions by modulating the TLR4-MyD88-NF-κB signaling pathway. Artemisinin B has shown potential in the treatment of neuroinflammatory diseases. | |||
T2573 |
Misoprostol
|
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Misoprostol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T2573,CAS号为 59122-46-2。 | |||
T131541 |
Artemisinin (Arteannuin, Qinghaosu, Qing Hau Sau)
|
||
Artemisinin (Arteannuin, Qinghaosu, Qing Hau Sau) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131541。 | |||
T72879 |
Misetionamide
|
||
Misetionamide,一种恶噻嗪类口服化合物,作为甘油醛-3-磷酸脱氢酶 (GAPDH) 抑制剂,展现出抗肿瘤活性,适用于癌症研究。 | |||
T126190 |
Vermisporin
|
||
Vermisporin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126190。 | |||
T130879 |
Altamisic acid
|
||
Altamisic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T130879。 | |||
T29995 |
Amisometradine
Aminoisometradin,Aminoisometradine,Rolicton |
||
Amisometradine is a diuretic which may be used in the treatment of congestive heart failure. | |||
T37288 |
Remisporine B
|
||
Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 μg/ml, respectively).1 1.Liu, H., Chen, S., Liu, W., et al.Polyketides with immunosuppressive activities from mangrove endophytic fungus Penicillium sp. ZJ-SY2Mar. Drugs14(12)217(2016) 2.Kong, F., and Carter, G.T.Remisporine B, a novel dimeric chrom... | |||
T21276 |
Amisulbrom
|
||
Amisulbrom is classified under the triazole group of fungicides. | |||
T65286 |
MES hemisodium salt
|
||
MES hemisodium salt 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65286,CAS号为 117961-21-4。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21065 |
Artemisitene
|
Others | Others |
Artemisitene 是青蒿素的氧化形式,是一种抗疟药。青蒿素前体是青蒿素生物合成的重要基础物质,包括青蒿素 B、青蒿素、青蒿酸等。 | |||
T8297 |
Gomisin N
|
Apoptosis | Apoptosis |
Gomisin N 是从五味子中分离得到的一种天然产物,有镇静和催眠生物活性。它具有用于治疗过敏和抑制癌症增殖和诱导细胞凋亡的潜力。 | |||
T5S0106 |
Peimisine
贝母辛,Ebeiensine |
RAAS; AChR | Endocrinology/Hormones; Neuroscience |
Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体,抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放,促进一氧化氮释放,可舒张气管平滑肌,有平喘作用。 | |||
TN1036 |
Gomisin D
戈米辛 D,戈米辛D |
Others | Others |
Gomisin D 是一种分离自五味子中的木脂素。它抑制 UDP-葡糖醛酸基转移酶活性,清除 ABTS(+) 自由基。 它是生脉散和参芪降糖颗粒的质量标志物,具有成为抗糖尿病药和抗阿尔茨海默病药的潜力。 | |||
TN1568 |
Deoxyartemisinin
2-deoxyartemisinin |
||
Deoxyartemisinin (2-deoxyartemisinin) 是一种口服有效的抗炎和抗溃疡化合物,可从青蒿素青蒿中分离得到。 | |||
TN1709 |
Gomisin O
5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-5-ol,戈米辛 O |
Others | Others |
Gomisin O (5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-5-ol) 是一种分离自五味子果实的物质。 | |||
T0392 |
Artemisinin
Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine |
HCV Protease; Ferroptosis; Akt; Parasite | Apoptosis; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
Artemisinin (Qinghaosu) 是一种倍半萜烯内酯,是从青蒿植物的地上部分分离的一种抗疟疾药物。它有神经保护和抗癌作用。 | |||
T6369 |
Adenine hemisulfate
硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐 |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Adenine hemisulfate (Diadenine sulphate) 是一种嘌呤,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。 | |||
TN2272 |
Tigloylgomisin H
|
Nrf2 | Immunology/Inflammation |
Tigloylgomisin H 是分离自S. chinensis 果实中的木酚素。Tigloylgomisin H 能诱导小鼠肝癌细胞 Hepa1c1c7 中醌还原酶活性。Tigloylgomisin H 是单功能诱导剂,通过 Nrf2-ARE 途径特异性上调 II 期解毒酶 NQO1。Tigloylgomisin H 是潜在的肝癌预防剂。 | |||
TN1018 |
Angeloylgomisin H
当归酰戈米辛 H,当归酰戈米辛H |
PPAR | DNA Damage/DNA Repair; Metabolism |
Angeloylgomisin H 是从五味子中提取的一种木脂素类天然产物。它通过激活PPAR-γ来改善胰岛素刺激的葡萄糖摄取潜力。 | |||
TQ0217 |
Gomisin G
戈米辛G,戈米辛 G |
P450; HIV Protease | Metabolism; Microbiology/Virology; Proteases/Proteasome |
Gomisin G 是一种有抗HIV 活性的天然产物。 | |||
TN1390 |
Angeloylgomisin Q
当归酰基戈米辛Q,当归酰戈米辛Q |
Others | Others |
Angeloylgomisin Q 是一种新二苯并环辛二烯类木脂素,提取自五味子茎中。它具有用于阿尔茨海默病研究的潜力。 | |||
T0607 |
Dihydroartemisinin
双氢青蒿素,β-Dihydroartemisinin,Dihydroqinghaosu,Artenimol,DHA |
Apoptosis; NF-κB; Parasite; Autophagy | Apoptosis; Autophagy; Microbiology/Virology; NF-κB |
Dihydroartemisinin (Artenimol) 是一种抗疟疾药物。 | |||
TN3396 |
Alpinumisoflavone acetate
4'-O-Acetylalpinumisoflavone |
Others | Others |
Alpinumisoflavone acetate (4'-O-Acetylalpinumisoflavone) 是一种新的alpinumisoflavone 衍生物。Alpinumisoflavone 在0.63 ug/disc 时强烈抑制生殖管生长。 | |||
T4S1452 |
Artemisic acid
(+)-Artemisinic Acid,青蒿酸,Artemisinic acid |
Antibacterial | Microbiology/Virology |
Artemisic acid ((+)-Artemisinic Acid) 是黄花蒿中分离得到的一种倍半萜,具有多种药理活性,如抗疟、抗菌和抗肿瘤活性,以及解热、化感和抗脂肪生成作用。 | |||
TN1511 |
Cleomiscosin A
|
LDL; Antioxidant; TNF | Apoptosis; Metabolism; oxidation-reduction |
Cleomiscosin A 来源于 Acer okamotoanum 的叶和树枝,对小鼠腹腔巨噬细胞的 TNF-α 分泌具有抑制活性。 Cleomiscosin A 可用于预防动脉粥样硬化病变中 LDL 氧化的研究。 | |||
T6564 |
Leupeptin Hemisulfate
亮肽素 |
Serine Protease; Cysteine Protease | Proteases/Proteasome |
Leupeptin hemisulfate 是一种蛋白酶抑制剂,具有细胞膜渗透性、可逆性、竞争性和口服活性。Leupeptin hemisulfate 可以抑制 Cathepsin B、Cathepsin H、Cathepsin L 的活性,阻断两性溶酶体的融合。Leupeptin hemisulfate 还具有抗炎活性。 | |||
T3904 |
Gomisin J
|
Calcium Channel; AMPK | Chromatin/Epigenetic; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling |
Gomisin J 是在五味子中发现的小分子量木脂素,具有血管舒张活性,在非酒精性脂肪性肝病方面有研究潜力。 它通过激活 AMPK、LKB1 和 Ca2+/钙调蛋白依赖性蛋白激酶 II 以及抑制 HepG2 细胞中的胎球蛋白 A 来调节脂肪生成酶和脂肪分解酶以及炎症分子的表达,从而抑制脂质积累。 | |||
TN3847 |
Dihydroalpinumisoflavone
|
||
Dihydroalpinumisoflavone 是一种从 Crotalaria madurensis 的叶子和茎中提取的天然产品。 | |||
THS1455 |
DihydroarteMisinic acid
双氢青蒿酸,Dihydro-Artmisinic Acid,二氢青蒿酸 |
Ferroptosis; Parasite | Apoptosis; Microbiology/Virology |
DihydroarteMisinic acid (Dihydro-Artmisinic Acid) 是青蒿的天然产物,是青蒿素的主要直接前体,青蒿素是一种广泛用于治疗疟疾的药草。 | |||
T7059 |
α-Dihydroartemisinin
α-Artenimol,α-Dihydroqinghaosu |
Parasite | Microbiology/Virology |
α-Dihydroartemisinin (α-Dihydroqinghaosu) 是青蒿素类抗疟化合物的中间体,具有良好的抗疟抗癌活性,可用于研究红斑狼疮。 | |||
TN3827 | Demissidine | Others | Others |
Demissidine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3827,CAS号为 474-08-8。 | |||
TN1609 | Epigomisin O | Others | Others |
Epigomisin O is a natural product from Schizandra chinensis. | |||
TN3494 | Benzoylgomisin P | Others | Others |
Benzoylgomisin P 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3494,CAS号为 129445-43-8。 | |||
TN4294 | Isogomisin O | Others | Others |
Isogomisin O是一种天然产物,属于五味子科五味子属,其产品编号为 TN4294,CAS号为 83916-76-1。Isogomisin O可用作对照参考。 | |||
TN3493 | Benzoylgomisin H | Others | Others |
Benzoylgomisin H is a natural product from Schizandra chinensis. | |||
T72903 | Artemisiane E | ||
Artemisiane E 是一种有效的PI3K/AKT 通路抑制剂,IC50为 8.9 μM。 | |||
TN5401 |
R(+)-Gomisin M1
R(+)-戈米辛M1 |
||
(+/-)-Gomisin M1 exhibits potent anti-HIV activity, with EC50 and therapeutic index (TI) values of <0.65 microM and >68, respectively. | |||
TN1318 |
Benzoylgomisin O
苯甲酰戈米辛O,6-O-benzoylgomisin O |
Others | Others |
6-O-benzoylgomisin O is a natural product from Schisandra sphenanthera. | |||
TN4821 |
Pregomisin
|
PAFR | GPCR/G Protein |
Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M. | |||
TN3384 |
alpha-Epoxydihydroartemisinic acid
|
Others | Others |
alpha-Epoxydihydroartemisinic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3384,CAS号为 380487-65-0。 | |||
T38036 | Lumisterol | ||
Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol. Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities[1]. [1]. Anyamanee Chaiprasongsuk, et al. Protective Effects of Novel Derivatives of Vitamin D 3 and Lumisterol Against UVB-induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms. Redox Biol. 2019 Jun;24:101206. | |||
TN6541 |
Cleomiscosin B
|
||
Cleomiscosins A, B and C exhibit liver-protective properties. Cleomiscosin B shows the potent anti-HIV-1 activity in vitro and also has protective effects on MT4 cells infected by HIV-1(IIIB). | |||
TN1389 |
Angeloylgomisin O
当归酰戈米辛O,当归酰戈米辛 O |
Others | Others |
Angeloylgomisin O is a nartural product from Schisandra chinensis. | |||
T13614 |
Cimiside B
|
Others | Others |
Cimiside B is a glycoside alkaloid isolated from the rhizome of Cimicifuga dahurica. | |||
TN4154 |
Gomisin L1
|
Others | Others |
(-)-Gomisin L1 induces G2/M arrest and apoptosis in human ovarian cancer cells. | |||
TN4156 |
Gomisin U
|
Others | Others |
Gomisin U 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4156,CAS号为 135095-46-4。 | |||
T81524 |
Peimisine 3-O-β-D-glucopyranoside
|
||
Peimisine 3-O-β-D-glucopyranoside (compound 1) 是一种从单苞贝母鳞茎中分离得到的甾体生物碱。该化合物对鱼藤酮诱导的PC12细胞系神经毒性展现出中等程度的保护效果。 | |||
TN4155 |
Gomisin L2
|
Others | Others |
Gomisin L2 is a natural product from Schizandra chinensis BAILL. | |||
TN1701 |
Glycosmisic acid
|
Others | Others |
Glycosmisic acid is a natural product from Nauclea officinalis. | |||
TN1708 |
Gomisin M2
五味子脂素 M2 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Gomisin M2 is an anti-HIV agent. | |||
TN1974 |
Angeloyl-(+)-gomisin K3
Negsehisandrin G,当归酰基-(+)-戈米辛 K3 |
Others | Others |
Negsehisandrin G is a natural product | |||
TN6628 | Tigloylgomisin O | ||
Tigloylgomisin O 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6628,CAS号为 130855-74-2。 | |||
TN3157 | 6-Demethoxy-9'-deoxycleomiscosin A | Others | Others |
6-Demethoxy-9'-deoxycleomiscosin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3157,CAS号为 121587-18-6。 | |||
TN1399 |
Arenobufagin 3-hemisuberate
沙蟾毒精 3-辛二酸单酯,沙蟾毒精3-辛二酸单酯 |
Others | Others |
Arenobufagin 3-hemisuberate is a natural product | |||
TN3675 | Cleomiscosin C | LDL | Metabolism |
Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl ( IC50s of 23.6 and 3.9 microM, respectively), suggests that it could be beneficial in preventing LDL oxidation in atheroscl | |||
TN2449 |
Anhydro Dihydro Artemisinin
|
Others | Others |
Anhydro Dihydro Artemisinin is a natural product from Artemisia carvifolia Buch.-Ham. ex Roxb. | |||
TN4153 |
Gomisin K1
|
Others | Others |
Gomisin K1 is a natural product from Schizandra chinensis BAILL. | |||
TN3655 |
Cimiside E
|
ERK; TNF; ROS; Akt; PI3K; PKC; PPAR | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; PI3K/Akt/mTOR signaling |
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agen | |||
TN4152 | Gomisin F | Others | Others |
Gomisin F是一种天然产物,属于五味子科五味子属,其产品编号为 TN4152,CAS号为 62956-47-2。Gomisin F可用作对照参考。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05176 |
AMH Protein, Human, Recombinant (His)
MIS,anti-Mullerian hormone,MIF |
Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi... | |||
TMPK-00977 |
AMHRII Protein, Human, Recombinant (hFc)
MISR2,AMHR2,AMH type II receptor,AMHR,C14,MIS |
Human | HEK293 Cells |
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women undergoing medically assisted reproduction. Three hundred in vitro fertilization or intracytoplasmic sperm injection patients constituted the study population, while 300 women with at least one spontaneous pregnancy participated as controls. AMHRII Protein, Human, Recombinant (hFc) is... | |||
TMPK-00976 |
AMHRII Protein, Human, Recombinant
MRII,AMHR2,AMH type II receptor,MIS type II recepto... |
Human | HEK293 Cells |
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women undergoing medically assisted reproduction. Three hundred in vitro fertilization or intracytoplasmic sperm injection patients constituted the study population, while 300 women with at least one spontaneous pregnancy participated as controls. AMHRII Protein, Human, Recombinant is expre... | |||
TMPY-01193 |
Influenza A H1N1 (A/Brevig Mission/1/1918) Hemagglutinin Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Brevig Mission/1/1918) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q9WFX3. | |||
TMPY-04274 |
Influenza A H1N1 (A/Brevig Mission/1/1918) Nucleoprotein/NP Protein (His)
NP Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Brevig Mission/1/1918) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is Q5UEW0.1. | |||
TMPY-05525 |
Art v 1 Protein, Artemisia vulgaris, Recombinant (His)
Art v 1,Defensin like protein 1 |
Artemisia vulgaris | HEK293 Cells |
Art v 1 Protein, Artemisia vulgaris, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is Q84ZX5.1. | |||
TMPH-00048 |
Pectate lyase 1 Protein, Ambrosia artemisiifolia, Recombinant (His)
|
Ambrosia artemisiifolia | E. coli |
Has pectate lyase activity. | |||
TMPH-03091 |
Silicatein Protein, Petrosia ficiformis, Recombinant (His & Myc)
|
Petrosia ficiformis | E. coli |
Polymerizes silica around the axial filament during spicule formation. Silicatein Protein, Petrosia ficiformis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is Q6YD92. | |||
TMPH-00159 |
Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO)
|
Bacillus licheniformis | E. coli |
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides (Ref.4, PubMed:11109488). Shows high specificity for aromatic and hydrophobic amino acids in the P1 substrate position. May play an important role in the degradation of feather keratin. Subtilisin Carlsberg Protein, Bacillus licheniformis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 42.0 kDa and the ac... | |||
TMPY-00496 |
Influenza A H1N1 (A/Brevig Mission/1/1918) Matrix protein 1/M1 Protein (His)
cholinergic receptor, muscarinic 1 |
H1N1 | E. coli |
Influenza A H1N1 (A/Brevig Mission/1/1918) Matrix protein 1/M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is Q8BAC3.1. | |||
TMPY-04667 |
Influenza A H3N2 (A/Missouri/09/2014) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Missouri/09/2014) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa. | |||
TMPH-03403 |
Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO)
|
Renilla reniformis | E. coli |
Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 56.0 kDa and the accession number is P27652. | |||
TMPH-00050 |
Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His & SUMO)
|
Ambrosia artemisiifolia | E. coli |
Has pectate lyase activity. Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.8 kDa and the accession number is P27759. | |||
TMPY-01079 |
Influenza A H1N1 (A/Brevig Mission/1/1918) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Brevig Mission/1/1918) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.6 kDa and the accession number is Q9WFX3. | |||
TMPH-00049 |
Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His)
|
Ambrosia artemisiifolia | P. pastoris (Yeast) |
Has pectate lyase activity. | |||
TMPY-04654 |
Influenza A H3N2 (A/Missouri/09/2014) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Missouri/09/2014) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.2 kDa. | |||
TMPY-00410 |
EPHX2 Protein, Human, Recombinant (His)
SEH,CEH,epoxide hydrolase 2, cytoplasmic |
Human | Baculovirus Insect Cells |
Genetic variation in EPHX2 was significantly associated with risk of incident CHD in Caucasians, implicating EPHX2 as a potential cardiovascular disease-susceptibility gene. Single nucleotide polymorphisms (SNPs) in the human EPHX2 gene had been implicated in susceptibility to cardiovascular disease, including stroke. The human EPHX2 mutations may in part explain the genetic variability in sensitivity to ischemic brain injury and stroke outcome. Epoxide hydrolase is involved in metabolism of vas... | |||
TMPJ-01187 |
Siglec-E Protein, Mouse, Recombinant (hFc)
SiglecE,Siglec-E |
Mouse | HEK293 Cells |
Siglecs are sialic acid specific I‑type lectins that are characterized by an extracellular domain (ECD) with an N‑terminal Ig‑like V‑set domain followed by varying numbers of Ig‑like C2‑set domains. Mouse Siglec‑E, also known as Myeloid Inhibitory Siglec (MIS), is an 80 ‑ 85 kDa member of the CD33‑related subfamily of Siglecs. Rodent and primate Siglec gene families have significantly diverged, and Siglec‑9 is the most likely human ortholog of mouse Siglec‑E. Siglec‑E is expressed as a heavily N... |