419
210
5
1
24
Cat. No. | Product Name | ||
---|---|---|---|
L2700 | 肾上腺素能受体化合物库 | 193 compounds | |
193 种特异靶向肾上腺素受体的生物活性小分子化合物的集合,是相关疾病药物筛选的有效工具; | |||
L2140 | 癌细胞分化化合物库 | 406 compounds | |
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L8000 | 干细胞分化化合物库 | 1197 compounds | |
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选; | |||
L2630 | 神经元分化化合物库 | 672 compounds | |
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发 | |||
L6210 | 藏药化合物库 | 747 compounds | |
747 种藏药来源的天然产物分子集合,可以用于高通量和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0051 |
Adrenergic Receptor antagonist/agonist kit
Adrenergic Receptor antagonist/agonist kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T28516 |
ReN-1869
NNC-05-1869,NNC 05-1869,NNC-051869,ReN 1869 |
||
ReN-1869 is a histamine H1 receptor antagonist. ReN 1869 is active against inflammation and neurogenic pain. ReN-1869 produces potent and selective antinociceptive effects on dorsal horn neurons after inflammation and neuropathy. | |||
T3561 |
CPI1189
CPI-1189,REN-1189,CPI 1189 |
TNF | Apoptosis |
CPI1189 (REN-1189) 是 TNF-α 释放抑制剂,具有神经保护作用及抗氧化作用。它可用于研究 HIV 相关神经毒性,具有成为 HIV 相关 CNS 疾病患者神经保护治疗药物的潜能。 | |||
T12703 |
ReN-1869 hydrochloride
NNC-05-1869 hydrochloride |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor. | |||
T73088 |
Mavodelpar
HPP593,REN001,REN001 ; HPP593 |
||
Mavodelpar (REN001) 是一种选择性的 PPARδ激动剂。Mavodelpar 抑制肾小球损伤和肾纤维化。Mavodelpar 可用于原发性线粒体肌病 (PMM) 和长链脂肪酸氧化障碍 (LC-FAOD) 的研究。 | |||
T16731 |
Rentiapril racemate
(Rac)-SA-446,SA-446 racemate,(Rac)-Rentiapril |
Angiotensin-converting Enzyme (ACE) | Metabolism |
Rentiapril racemate (SA-446 racemate) 是 Rentiapril 的外消旋体。Rentiapril racemate 具有抗炎活性,可用于研究青光眼。 | |||
T0948 |
Adrenalone hydrochloride
Adrenalone HCl,肾上腺酮盐酸盐,盐酸肾上腺酮 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Adrenalone hydrochloride (Adrenalone HCl) 是一种多巴胺β氧化酶 (dopamine β oxidase) 抑制剂,结构与去甲肾上腺素转运蛋白 (NET) 配体相似,IC50=36.9 μM。它是一种肾上腺素能 (adrenergic) 激动剂,用作局部血管收缩剂和止血剂。 | |||
T76874 |
Erenumab
AMG-334 |
CGRP Receptor | GPCR/G Protein; Neuroscience |
Erenumab是一种全人单克隆抗体,作用于抑制降钙素基因相关肽(CGRP)受体,用于预防发作性偏头痛。 | |||
T76707 |
Brentuximab vedotin
SGN-35 |
Others | Others |
Brentuximab vedotin (SGN-35) 是一种靶向 CD30 的抗体-活性分子偶联物 (ADC),具有抗肿瘤活性,可研究淋巴瘤。 | |||
T20094 |
Adrenochrome
Adraxone |
Antioxidant | oxidation-reduction |
Adrenochrome (Adraxone) 是一种细胞毒性分子,可用于杀死细菌。Adrenochrome 是 Epinephrine 的氧化产物。Adrenochrome 是一种可作用于大鼠心脏的冠状动脉收缩化合物,与心脏毒性有关,可用于确定超氧化物歧化酶的活性。Adrenochrome 与可用于神经系统疾病研究,是拟精神病的潜在药物。 | |||
T76718 |
Brentuximab
|
TNF | Apoptosis |
Brentuximab 是靶向 CD30 的嵌合抗体,是 Brentuximab vedotin 的裸抗。Brentuximab 具有抗肿瘤活性,可用于研究复发或难治性霍奇金淋巴瘤。 | |||
T16044 |
Methoprene
烯虫酯,ZR-515 |
Others | Others |
Methoprene (ZR-515) 是一种保幼激素模拟物和一种生物杀虫剂。Methoprene 作为昆虫生长调节剂,干扰昆虫的生命周期并阻止其成熟或繁殖。 | |||
T20290 |
Thianthrene
AI3 00638,AI300638,NSC-439,AI3-00638,噻蒽,dibenzo-1,4-dithiin,9,10-Dithiaanthracene,NSC439,Dibenzodithiodioxane,NSC 439 |
Others | Others |
Thianthrene (Dibenzodithiodioxane) 是一种含硫杂环化合物,是称为二硫因的母体杂环的衍生物,易于氧化。 | |||
T64393 |
6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile
|
Others | Others |
6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile 是一种生物活性化合物,可用于化学和生命科学领域的研究。 | |||
T28950 |
Terlakiren
CP 80794,CP-80,794 |
RAAS | Endocrinology/Hormones |
Terlakiren (CP-80,794) 是一种具有口服活性和高效性的肾素 (Renin) 抑制剂,抑制人肾素的效能,可用于研究高血压类的神经系统疾病。 | |||
T8633 |
9-FLUORENOL
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
9-FLUORENOL 是一种多巴胺再摄取抑制剂,IC50 为 9 µM,是一种化合物的主要代谢物,被开发为一种觉醒促进剂。 | |||
T1056 |
Isoprenaline hydrochloride
NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl,盐酸异丙肾上腺素 |
PI3K; Endogenous Metabolite; Adrenergic Receptor; PDE | GPCR/G Protein; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling |
Isoprenaline hydrochloride (NCI-c55630) 是非选择性的β-肾上腺素能受体激动剂,有支气管扩张剂,外周血管扩张剂和心脏刺激活性。 | |||
TP1240 |
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA
CLIP (human) (TFA) |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA (CLIP human TFA) 是一种似皮质促素中叶肽,由垂体中叶的促黑素细胞产生。 | |||
T36587 |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt
|
Others | Others |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt 是一种阴离子荧光染料,用作葡萄糖传感和检测其他糖类的报告分子。激发/发射光谱为 425/503 nm。 它可以在溶液中使用,也可以通过还原胺化连接醛官能化单体来固定,而不会显著改变荧光强度。 | |||
T9704 |
1-Ethynylpyrene
|
P450 | Metabolism |
1-Ethynylpyrene 是有效的细胞色素P450 1A1, 1A2和2B1抑制剂,抑制的IC50分别为 0.18,0.32 和 0.04 μM。 | |||
T76684 |
Girentuximab
cG250,WX-G250,G250 |
Carbonic Anhydrase | Metabolism |
Girentuximab (G250) 是一种有效的抗碳酸酐酶 IX (CAIX)单克隆抗体,具有抗癌活性,可用于研究尿路上皮癌 PET (ZiPUP)。 | |||
T22517 |
5,7-Dichlorokynurenic acid
5,7-二氯犬尿喹啉酸,5,7-dichlorokynurenic acid sodium,5,7-DCKA |
NMDAR | Neuroscience |
5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) 是一种专门针对于NMDA 受体甘氨酸位点的竞争性拮抗剂(KB:65 nM)。它是犬尿酸的衍生物,可降低大鼠皮质细胞培养物中 NMDA 诱导的神经元损伤程度。 | |||
T5008 |
Teprenone
Tetraprenylacetone,Geranylgeranylacetone,替普瑞酮 |
HSP | Cytoskeletal Signaling; Metabolism |
Teprenone (Geranylgeranylacetone) 是一种热休克蛋白诱导剂,有抗溃疡作用。 | |||
T4560 |
Alprenolol
Alpheprol,阿普洛尔,(RS)-Alprenolol,dl-Alprenolol |
5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Alprenolol (Alpheprol) 是一种非选择性β受体阻滞剂,也是5-HT1A 受体拮抗剂。 | |||
T5843 |
Tarenflurbil
MPC7869,(R)-Flurbiprofen,R-flurbiprofen,氟比洛芬,R-氟比洛芬 |
Retinoid Receptor; Autophagy | Autophagy; Metabolism |
Tarenflurbil ((R)-Flurbiprofen) 是 Flurbiprofen 的 R 型对映体,可抑制 [3H]9-cis-RA 结合到 RXRαLBD,IC50为 75 μM。它可研究阿尔兹海默症。 | |||
T25984 |
Prenalterol
H80/62,H-80/62,H 80/62 |
||
Prenalterol 是一种选择性的β1- 肾上腺素能受体激动剂,不影响肠道平滑肌的收缩活动。Prenalterol 具有心血管疾病的研究潜力。 | |||
T68182L |
3-Hydroxykynurenamine HCl
3-OH-Kynurenamine HCl,3-Hydroxykynurenamine HCl(99362-47-7 Free base) |
Others | Others |
3-Hydroxykynurenamine HCl (3-OH-Kynurenamine HCl) 是一种免疫调节生物胺,是氨基酸分解代谢的中间体,可诱导氧化损伤和促进细胞死亡。 | |||
T64322 |
4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester
|
Others | Others |
4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester 是一种取代的哌啶衍生物,在有机合成中被广泛用作形成肽和拟肽分子的连接体,被广泛应用于肽合成和肽模拟,也用于合成药物、生物聚合物和其他有机分子。 | |||
T0083 |
Eplerenone
Epoxymexrenone,CGP 30083,依普利酮,SC-66110 |
Glucocorticoid Receptor | Endocrinology/Hormones |
Eplerenone (CGP 30083) 是一种竞争性的、选择性的、具有口服活性的醛固酮 (aldosterone) 拮抗剂,IC50=138 nM。它对孕酮,雄激素,雌激素和糖皮质激素受体的亲和力低,可用于研究高血压和心肌梗死后的心力衰竭。 | |||
T0277 |
Metaproterenol hemisulfate
Orciprenaline sulfate,Metaproterenol Sulfate,硫酸奥西那林 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Metaproterenol hemisulfate (Orciprenaline sulfate) 是一种 β2-肾上腺素能受体 (β2AR) 激动剂(IC50=68 nM),是一种直接作用的拟交感神经药,具有抗炎活性。 | |||
T8312 |
Derenofylline
|
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Derenofylline 是一个有选择性的、具有口服活性的腺苷A1受体的拮抗剂,可抑制心肌纤维化,降低蛋白尿,对腺苷A1、A3和A2A 受体的Ki 值分别为 1、200 和 398 nM。 | |||
T22236 |
Alprenolol hydrochloride
阿普洛尔盐酸盐,盐酸阿普洛尔 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Alprenolol hydrochloride 是一种非选择性β受体阻滞剂,也是5-HT1A 受体拮抗剂。 | |||
T1520 |
Aliskiren hemifumarate
阿利克仑半富马酸盐,CGP 60536,SPP 100,CGP60536B |
RAAS; Autophagy | Autophagy; Endocrinology/Hormones |
Aliskiren hemifumarate (CGP60536B) 一种可口服非肽肾素抑制剂,IC50为1.5 nM,具有抗高血压活性。 | |||
T13591 |
Calcium polystyrene sulfonate
Poly(styrenesulfonic acid) calcium salt,聚苯乙烯磺酸钙 |
Others | Others |
Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) 是一种离子交换树脂。 Calcium polystyrene sulfonate 可降低血钾水平,可用于治疗慢性肾病患者高钾血症的研究。 | |||
T3096 |
Canrenoate potassium
坎利酸钾,Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone |
Glucocorticoid Receptor | Endocrinology/Hormones |
Canrenoate potassium (Soldactone) 是一种有效的竞争性盐皮质激素受体 (mineralocorticoid receptor) 拮抗剂,是一种释放 canrenone 的前药。它作为一种利尿剂,用于高血压的研究。 | |||
T21285 |
2-Aminofluorene
2-Fluorenamine,2-氨基芴 |
Others | Others |
2-Aminofluorene (2-Fluorenamine) 是一种生化物质。 | |||
TQ0038 |
Brensocatib
AZD7986,INS 1007 |
Proteasome | Proteases/Proteasome; Ubiquitination |
Brensocatib (AZD7986) 是一种二肽基肽酶 1 (DPP1) 抑制剂,在人,小鼠,大鼠,狗和兔中的pIC50分别为 6.85, 7.6, 7.7, 7.8 和 7.8。 | |||
T0119 |
Nitrendipine
BAY-E-5009,Bayotensin,尼群地平 |
Calcium Channel; Autophagy | Autophagy; Membrane transporter/Ion channel; Metabolism |
Nitrendipine (BAY-E-5009) 是 Nifedipine 的类似物,是一种钙通道阻滞剂,具有显着的血管扩张作用。它是一种有效的抗高血压药且不会降低肾小球滤过率,并且具有轻微的利钠作用。 | |||
T7804 |
Garenoxacin mesylate hydrate
Garenoxacin mesylate [USAN],加雷沙星甲磺酸盐,BMS284756 (Mesylate hydrate) |
Antibacterial | Microbiology/Virology |
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) 是一种新型口服 des-fluoro(6) 喹诺酮,具有强抗菌活性,抗呼吸道病原体。 | |||
T31577 |
Droprenilamine
Valcor |
||
Droprenilamine (Valcor) 是戊烯胺的脂环族衍生物,具有抗心绞痛作用。 | |||
TP1244L1 |
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base) |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 是促肾上腺皮质激素的一个片段。 Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 仅在 100 和 1000 nM 时具有较弱的 α-MSH 效力。 | |||
T2599 |
Pirenperone
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
Pirenperone 是5-HT2血清素受体拮抗剂,具有一定抗焦虑作用。 | |||
T4414 |
Eprenetapopt
APR-246,PRIMA-1Met |
Apoptosis; Others; Ferroptosis; p53; Autophagy | Apoptosis; Autophagy; Others |
Eprenetapopt (PRIMA-1Met) 是一种在 TP53突变细胞中恢复野生型 p53功能的小分子,可引发肿瘤细胞凋亡,还抑制硒蛋白硫氧还蛋白还原酶 1。 | |||
T4047 |
Bisantrene
CL216942,比生群 |
Topoisomerase | DNA Damage/DNA Repair |
Bisantrene (CL216942) 是一种具有抗肿瘤活性的蒽基双腙,可靶向作用于真核生物的 II 型拓扑异构酶。它插入并破坏 DNA 的构型,导致 DNA 单链断裂、DNA-蛋白质交联和 DNA 复制的抑制。 | |||
T1405 |
Cefditoren pivoxil
头孢妥仑匹酯,ME 1207,Cefditoren pivaloyloxymethyl ester,Cefditoren pivoxyl |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefditoren pivoxil (ME 1207) 是一种半合成、广谱、β-内酰胺酶耐药的第三代头孢菌素抗生素,具有杀菌活性。 | |||
T7567L |
Adrenorphin 3TFA(88377-68-8(free base))
Metorphamide |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) 是 μ-opioid 受体 (Ki :12 nM) 的激动剂。 | |||
T0248 |
Clorprenaline hydrochloride
盐酸氯丙那林,Clorprenaline HCl,NSC 334693 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Clorprenaline hydrochloride (Clorprenaline HCl) 是 β2-肾上腺素受体激动剂,与支气管扩张有关,可用于研究哮喘。 | |||
T7112 |
Ibutamoren Mesylate
MK-0677,伊布莫仑甲磺酸盐,MK-677 |
GHSR | GPCR/G Protein |
Ibutamoren Mesylate (MK-0677) 是非肽段类生长激素促分泌素受体 (GHSR) 激动剂,也是一种口服有活性的生长激素 (GH) 促分泌素。 | |||
T10961 |
Darenzepine
|
AChR | Neuroscience |
Darenzepine 是一种毒蕈碱受体抑制剂。 | |||
T77364 |
Sibeprenlimab
VIS649,VIS-649 |
Others | Others |
Sibeprenlimab (VIS649) 是一种抑制 APRIL 的人源化IgG 2单克隆抗体。Sibeprenlimab 对 APRIL 有抑制作用,可用于研究预防和治疗 肾病(IgAN)。 | |||
T6761 |
Ossirene
AS101 |
IL Receptor; Caspase; Interleukin | Apoptosis; Immunology/Inflammation; Proteases/Proteasome |
Ossirene (AS101) 是一种免疫调节抑制剂,是一种新型 IL-1beta 转化酶抑制剂,可用于自身免疫性疾病和某些恶性肿瘤。它通过抑制IL-10消除 STAT3 的磷酸化,有效抑制Caspase-1。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10233 |
Acetylarenobufagin
|
HIF | Angiogenesis; Chromatin/Epigenetic |
Acetylarenobufagin 是一种类固醇缺氧诱导因子-1 (HIF-I) 调节剂。 | |||
T6985 |
Benzo[a]pyrene
苯并[a]芘,3,4-Benzopyrene,苯并(a)芘 |
Others | Others |
Benzo[a]pyrene (3,4-Benzopyrene) 在动物模型中显示肺致癌性,可用于化学预防研究。 | |||
T0354 |
Canrenone
6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,坎利酮,RP-11614,SC14266 |
Glucocorticoid Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Canrenone (SC14266) 是一种醛固酮 (aldosterone) 拮抗剂,广泛用作利尿剂。 | |||
T65135 |
Kynurenic acid
Fibrostop 2,Quinurenic acid |
GPR; GluR; NMDAR | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Kynurenic acid (Quinurenic acid) 是一种内源性色氨酸活性代谢物,是一种 NMDA, glutamate, α7 nicotinic acetylcholine receptor 三重拮抗剂,也是 GPR35/CXCR8 激动剂,具有神经保护和抗惊厥特性,可用于研究神经分裂和与代谢相关的疾病。 | |||
TN1146 |
8-Prenylnaringenin
8-Prenylnaringenin,8-异戊烯基柚皮素 |
Apoptosis; ROS | Apoptosis; Immunology/Inflammation |
8-prenylnaringenin 是一种从啤酒花穗中分离到的异戊烯类黄酮,具有细胞毒性。它能通过激活小鼠 Akt 磷酸化途径,使其从静止诱导的停用性肌肉萎缩中恢复。它能通过诱导内源性和外源性通路介导的凋亡,对 HCT-116 结肠癌细胞产生抗增殖活性。 | |||
T4928 |
L-Kynurenine
L-犬尿氨酸,(S)-Kynurenine |
AhR; Aryl Hydrocarbon Receptor; Endogenous Metabolite | Immunology/Inflammation; Metabolism |
L-Kynurenine ((S)-Kynurenine) 是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。 | |||
TN6795 |
5-Methoxysuberenone
|
Others | Others |
5-Methoxysuberenone 是 Toddalia asiatica (L.) Lam 根皮的化学成分。 (T. aculeata Pers.),芸香科。 | |||
T3010 |
Xanthurenic Acid
8-Hydroxykynurenic acid,黄尿酸,4,8-Dihydroxyquinaldic acid,xanthurenate |
Apoptosis; Endogenous Metabolite; GluR | Apoptosis; Metabolism; Neuroscience |
Xanthurenic Acid (8-Hydroxykynurenic acid) 是通过 3-羟基犬尿氨酸转氨而由色氨酸代谢产生的分子,可激活 mGlu2/3 代谢型谷氨酸受体。在下丘脑的感觉传输过程中,它被认为是Group II 代谢型谷氨酸受体的激动剂。 | |||
TN1658 | Ganoderenic acid D | Apoptosis; Others | Apoptosis; Others |
Ganoderenic acid D 是从灵芝提取物 (GLE) 的有效化合物中分离出来的天然产物。 Ganoderenic acid D 诱导细胞周期停滞和细胞凋亡并抑制癌细胞的增殖。 | |||
T5744 |
7-Prenyloxycoumarin
7-(异戊烯基氧基)香豆素,Nsc267697,7-O-Prenylumbelliferone,7-异戊烯氧基香豆素 |
Antifungal | Microbiology/Virology |
7-Prenyloxycoumarin (Nsc267697) 是一种 Heracleum dissectum 的天然产物,对乳腺癌具有预防和治疗作用。 | |||
T3929 |
Kaurenoic acid
Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid |
Others | Others |
Kaurenoic acid (kaurenoate) 是一种二萜,来源于 Sphagneticola trilobata 中,可以抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路,并抑制炎症疼痛。 | |||
TN1459 |
Bufarenogin
3beta,12beta,14-Trihydroxy-11-oxo-5beta-bufa-20,22-dienolide,伪异沙蟾毒精 |
ERK; MEK; PI3K | MAPK; PI3K/Akt/mTOR signaling |
Bufarenogin (3beta,12beta,14-Trihydroxy-11-oxo-5beta-bufa-20,22-dienolide) 是一种从古巴地方性蟾蜍 Peltophryne fustiger 的腮腺分泌物中分离出来的蟾蜍二烯内酯。 Bufarenogin 显示出抗肿瘤活性。 | |||
T10993 |
δ-Amyrenone
Delta-Amyrone,Α-香树脂酮 |
Others | Others |
δ-Amyrenone (Delta-Amyrone) 分离自 S. lineare,具有抗炎作用。 | |||
T7974 |
Lynestrenol
|
Progesterone Receptor | Others |
Lynestrenol 是孕烷 X 受体 (PXR) 激动剂,能够作用于 hPXR(EC50:41 µM) 和 zfPXR(EC50:0.23 µM)。它是合成的孕酮,具有免疫刺激作用。 | |||
T8292 |
(-)-Cedrene
α-柏木烯,Alpha-Cedrene |
Others; Antibacterial | Microbiology/Virology; Others |
(-)-Cedrene (Alpha-Cedrene) 是一种来自雪松油中的倍半萜烯,有抗白血病、抗菌和抗肥胖作用。 | |||
T10109 |
3-Carene
Delta-3-Carene |
COX; Antifungal | Immunology/Inflammation; Microbiology/Virology; Neuroscience |
3-Carene(Delta-3-Carene) 是西部落叶松和花旗松中提取的双环单萜烯,可做为植物杀菌剂。3-Carene 对痛觉刺激引起的炎症浸润和 COX-2 过表达有抑制作用。3-Carene 具有抗伤害作用,能促进成骨细胞分化的早期标志物碱性磷酸酶的活性和表达。 | |||
TN1656 |
Ganoderenic acid A
灵芝烯酸A,灵芝烯酸 A |
Others | Others |
Ganoderenic acid A 是三萜类化合物。它对 CCl4 诱导的肝损伤具有保护作用。它是β-葡萄糖醛酸酶抑制剂。 | |||
TN6778 |
Umbelliprenin
伞形花醚,7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin |
IL Receptor | Immunology/Inflammation |
Umbelliprenin (7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin) 可减轻神经性疼痛,并降低血清 IL-6 水平和氧化应激。 | |||
T5A2455 |
Arenobufagin
沙蟾毒精,沙蟾毒经 |
Others | Others |
Arenobufagin 是一种蟾蜍甾烯,从蟾蜍毒液中提取得到,具有抗癌活性。 | |||
TN6762 |
(+)-Cuparene
|
Others | Others |
(+)-Cuparene 是一种生物活性化学品。 | |||
T4S1247 |
14-Hydroxy sprengerinin C
14-羟基麦冬皂苷C,14-羟基麦冬皂苷 C |
Others | Others |
14-Hydroxy sprengerinin C 是一种甾体化合物,提取自麦冬。 | |||
TQ0065 |
Pseudobufarenogin
伪异沙蟾毒精,ψ-Bufarenogin |
Others | Others |
Pseudobufarenogin (ψ-Bufarenogin) 是一种蟾蜍毒素提取物,活性背景未知。 | |||
T6S1665 |
Irisflorentin
|
Others; NO Synthase | Immunology/Inflammation; Others |
Irisflorentin 是天然存在的异黄酮,是大量存在于 Rhizoma Belamcandae 中的活性成分。它明显抑制了诱导型一氧化氮合酶的转录和翻译以及 NO 产生。 | |||
T19180 |
Adrenic Acid
二十二碳四烯酸,廿二碳四烯酸,cis-7,10,13,16-Docosatetraenoic acid |
Endogenous Metabolite | Metabolism |
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) 是一种天然的多不饱和脂肪酸,主要存在于肾上腺,肾脏,大脑和脉管系统中。Adrenic Acid 能够调节肾上腺皮质血管的血管紧张度。Adrenic Acid 也是非酒精性脂肪肝疾病的炎症增强剂。 | |||
T4S1943 |
Kirenol
奇壬醇,奇任醇,Kirel |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
Kirenol (Kirel) 是分离自 Siegesbeckia orientalis 中的,具有抗氧化、抗炎、抗过敏、抗关节炎活性,可用于缓解疼痛的研究。 | |||
TN6773 |
Acetoxyvalerensre
acetylvalerenolic acid |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Acetoxyvalerensre (acetylvalerenolic acid) 是缬草酸的衍生物,它是一种 GABAA 受体调节剂。 | |||
T8247 |
(+)-Aromadendrene
|
Anti-infection | Microbiology/Virology |
(+)-Aromadendrene 是一种天然产物,对革兰氏阳性菌和革兰氏阴性菌具有显着的抗菌活性。 | |||
TN6767 |
ACETOXYVALERENIC ACID
|
Others | Others |
Acetoxyvalerenic acid 是从 valerian 中提取的天然产物。 | |||
TN1153 |
Polyporenic acid C
猪苓酸C,聚孔酸C |
Apoptosis; PARP; Caspase; PI3K | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
Polyporenic acid C 是从茯苓中分离出的一种羊毛甾烷型三萜,可通过死亡受体介导的凋亡途径诱导细胞凋亡,有用于肺癌的研究潜力。 | |||
TN5770 |
Gingerenone A
|
Nrf2 | Immunology/Inflammation |
Gingerenone A 是一种有效的 Nrf2-Gpx4 激活剂,是从生姜里面分离出来的小分子化合物,具有抗癌活性,可延长癌细胞的细胞周期,可抑制右旋糖酐硫酸钠 (DSS) 诱导的结肠炎小鼠继发性肝损伤 (SLI) 中的铁死亡。 | |||
TN1195 |
17-Hydroxy sprengerinin C
17-羟基麦冬皂苷C |
BCL; Others; Caspase | Apoptosis; Others; Proteases/Proteasome |
17-Hydroxy sprengerinin C 是从黄精的根茎中分离得到的一种糖苷化合物,具有更强的抗癌活性。17-Hydroxy sprengerinin C 降低 Blc-2 和 pro-caspase3 的表达并增加 Bax 的产生。 | |||
T10938 |
D-Kynurenine
D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 |
GPR; AhR; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism |
D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。 | |||
T5621 |
β-Phellandrene
beta-Phellandrene,3-异丙基-6-亚甲基-1-环己烯,p-mentha-1(7),2-diene,(±)-beta-水芹烯 |
Others | Others |
β-Phellandrene (p-mentha-1(7),2-diene) 是由加拿大香脂油分馏取得,可用作精油添加剂。 | |||
TN2329 |
Zingiberen newsaponin
Zingiberensis saponin I,盾叶新苷 |
PARP; PAFR; Caspase | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Proteases/Proteasome |
Zingiberen newsaponin 是分离自盾叶薯 (Dioscorea zingiberensis) 中。 它能够诱导血小板聚集。 | |||
T2S1120 |
Ganoderenic acid B
|
P-gp | Membrane transporter/Ion channel; Neuroscience |
Ganoderenic acid B 是一种从Ganoderma lucidum 中提取的天然产物,可以通过抑制ABCB1的转运功能,增强化疗药物对ABCB1介导的耐多药癌细胞的细胞毒性来发挥作用。 | |||
TN1252 |
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone
|
Others | Others |
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone is a natural product from Morus alba. | |||
T19082 |
1-Hydroxypyrene
1-Pyrenol,Pyren-1-ol,1-羟基芘 |
Endogenous Metabolite | Metabolism |
1-Hydroxypyrene (1-Pyrenol) 是一种暴露于多环芳烃的生物标志物,存在尿液样本中,也是一种暴露于 pyrenes 中的主要生物标志物。 | |||
TN4442 |
Linderene acetate
|
Prolyl Endopeptidase (PREP) | Metabolism; Proteases/Proteasome |
Linderene acetate 是一种脯氨酸肽链内切酶抑制剂,分离自Lindera strychnifolia 中。 | |||
TN7234 |
Prenyletin
|
Others | Others |
Prenyletin 是一种天然产物,存在于多叶双峰、多角翼龙中。 | |||
TN7111 |
Hydroxyisogermafurenolide
|
Others | Others |
Hydroxyisogermafurenolide 是来自姜黄的天然产物。 | |||
T2207 |
Adrenosterone
肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G |
Androgen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Adrenosterone (11-ketoandrostenedione) 是一种人内源性代谢物,由肾上腺皮质产生。Adrenosterone 是一种竞争性羟基类固醇脱氢酶 1 抑制剂。它是一种的类固醇激素,具有较弱的雄激素特性。它是一种膳食补充剂,能够减少脂肪并提高肌肉质量。它能够抑制人类癌细胞的转移进展。 | |||
T1071L |
DL-Adrenaline Hydrochloride
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
DL-Adrenaline Hydrochloride 是天然存在的拟交感神经胺的盐酸盐,具有收缩血管、降低眼内压的活性。 | |||
TN1325 |
(2S)-6-Prenylnaringenin
(2S)-6-异戊烯基柚皮素,6-异戊二烯基柚皮素,6-Prenylnaringenin,6-PN |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
(2S)-6-Prenylnaringenin (6-Prenylnaringenin) 是强效植物雌激素 8-prenylnaringenin 的异构体,是前脑中最有效的化合物,在 α+β 结合位点上起GABAA 正变构调节剂的作用。 | |||
T10191L |
7-Chlorokynurenic acid
7-chloro-4-hydroxy-2-carboxyquinoline,7-氯犬尿酸,7-CKA |
GluR; NMDAR | Neuroscience |
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) 是一种有效的选择性 NMDA 受体拮抗剂,对甘氨酸 B 激动剂位点的 IC50 为 0.56 μM。 7-Chlorokynurenic acid 抑制谷氨酸再摄取到突触小泡中,Ki 为 0.59 μM,并在神经轴输送后显示出镇痛作用。 | |||
T82956 |
Asparenyldiol
Asparenydiol |
||
Asparenyldiol(Asparenydiol)为一类抗氧化剂且兼具点击化学试剂功能。该化合物含Alkyne基团,能够通过CuAAc与含Azide基团的分子发生反应。 | |||
T23774 |
Bauerenol
NSC 147745,Baurenol |
||
Bauerenol is a triterpenoid from Indian Suregada angustifolia. It also induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma cells. | |||
TN5722 | 1,6-Dimethyl-4,5-dihydropyrene-2,7-diol | ||
1,6-Dimethyl-4,5-dihydropyrene-2,7-diol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5722,CAS号为 2255331-28-1。 | |||
TN3089 | 5,7,4-Trihydroxy-3,6-dimethoxy-3-prenylflavone | Others | Others |
5,7,4-Trihydroxy-3,6-dimethoxy-3-prenylflavone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3089,CAS号为 959421-20-6。 | |||
TN2493 | 1,4,5,6-Tetrahydroxy-7-prenylxanthone | Others | Others |
1,4,5,6-Tetrahydroxy-7-prenylxanthone has anti-cancer activity, it shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines; it also exhibits moderate activities with GI50 (Growth inhibitory) values of 2. | |||
TN6194 | 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole | ||
1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6194,CAS号为 484678-79-7。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00908 |
Renin Protein, Human, Recombinant (His)
REN,renin,FLJ10761,HNFJ2 |
Human | HEK293 Cells |
Renin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is P00797-1. | |||
TMPY-04483 |
IRAK4 Protein, Human, Recombinant (His)
IPD1,NY-REN-64,REN64,interleukin-1 recepto... |
Human | Baculovirus Insect Cells |
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ... | |||
TMPY-01231 |
Renin Protein, Mouse, Recombinant (His)
Ren-A,Ren-1,Ren1,Ren1d,<... |
Mouse | HEK293 Cells |
Renin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.2 kDa and the accession number is P06281. | |||
TMPY-05808 |
Renin Protein, Human, Recombinant (R66K, His)
REN,FLJ10761,renin,HNFJ2 |
Human | HEK293 Cells |
Renin Protein, Human, Recombinant (R66K, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.74 kDa and the accession number is P00797-1. | |||
TMPJ-00797 |
LDHB Protein, Human, Recombinant (His)
LDH-B,Renal Carcinoma Antigen NY-REN-46,LD... |
Human | E. coli |
L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver.... | |||
TMPJ-00724 |
LDHA Protein, Human, Recombinant (His)
LDH-M,Renal Carcinoma Antigen NY-REN-59,Ce... |
Human | E. coli |
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria. | |||
TMPJ-00755 |
CRYAB Protein, Human, Recombinant (His)
α(B)-Crystallin,Alpha(B)-Crystallin,Heat Shock Protein Beta-... |
Human | E. coli |
α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and or... | |||
TMPJ-01010 |
PLA2G16 Protein, Human, Recombinant (His)
Renal Carcinoma Antigen NY-REN-65,HRAS-Lik... |
Human | E. coli |
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models. | |||
TMPH-02881 |
Renin-2 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Its function in the salivary gland is not understood. Renin-2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.0 kDa and the accession number ... | |||
TMPH-03403 |
Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO)
|
Renilla reniformis | E. coli |
Renilla-type luciferase Protein, Renilla reniformis, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 56.0 kDa and the accession number is P27652. | |||
TMPH-00287 |
Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)
Ferredoxin--NADP(+) reductase,ADXR,NADPH:adrenodoxi... |
Bovine | E. coli |
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 55.8 kDa and the accession number is ... | |||
TMPH-02411 |
Lol p 1 Protein, Lolium perenne, Recombinant (His & Myc)
|
Lolium perenne | E. coli |
Lol p 1 Protein, Lolium perenne, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is P14946. | |||
TMPH-00220 |
Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His)
Hepato-ferredoxin,FDX1,Ferredoxin-1,Adrenodoxin, mi... |
Bovine | E. coli |
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage to produce pregnenolone, the precursor of most steroid hormones. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Adrenodoxin, mitochondrial Protein, Bov... | |||
TMPH-02366 |
Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO)
|
JUNV | E. coli |
Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 79.0 kDa and the accession number is P14239. | |||
TMPH-02410 |
Lol p 5a Protein, Lolium perenne, Recombinant (His & Myc & SUMO)
|
Lolium perenne | E. coli |
Lol p 5a Protein, Lolium perenne, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 48.4 kDa and the accession number is Q40240. | |||
TMPH-02353 |
Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO)
|
H1N1 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPY-02418 |
kynureninase/KYNU Protein, Mouse, Recombinant (His)
kynureninase,4432411A05Rik |
Mouse | Baculovirus Insect Cells |
kynureninase/KYNU Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.7 kDa and the accession number is Q9CXF0. | |||
TMPH-02023 |
Renin receptor Protein, Human, Recombinant (His)
|
Human | E. coli |
Renin receptor Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02880 |
Renalase Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Renalase Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.0 kDa and the accession number is A7RDN6. | |||
TMPY-02479 |
kynureninase/KYNU Protein, Human, Recombinant (His)
KYNUU,kynureninase |
Human | Baculovirus Insect Cells |
kynureninase/KYNU Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.80 kDa and the accession number is Q16719. | |||
TMPH-00288 |
Adrenodoxin reductase Protein, Bovine, Recombinant (His)
Ferredoxin reductase,Adrenodoxin reductase,Ferredox... |
Bovine | P. pastoris (Yeast) |
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 52.8 kDa and the accession number is P08165. | |||
TMPY-02839 |
Adrenomedullin Protein, Human, Recombinant (hFc)
AM,PAMP,adrenomedullin |
Human | HEK293 Cells |
Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the calcitonin gene-related peptide. Adrenomedullin has a highly expression in pheochromocytoma and adrenal medulla. It also can be detected in lung, ventricle and kidney tissues. Adrenomedullin and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been report... | |||
TMPY-01451 |
MESDC2 Protein, Human, Recombinant (His)
MESD,mesoderm development candidate 2,BOCA |
Human | HEK293 Cells |
MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside... | |||
TMPY-02176 |
Harmonin/USH1C Protein, Human, Recombinant (His)
PDZD7C,PDZ-73,PDZ73,DFNB18A,PDZ-73/NY-CO-38,DFNB18,NY-CO-37,... |
Human | E. coli |
Harmonin, also known as Antigen NY-CO-38 / NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, Usher syndrome type-1C protein and USH1C, is a protein that is expressed in small intestine, colon, kidney, eye and weakly in pancreas. USH1C is expressed also in vestibule of the inner ear. USH1C contains 3 PDZ (DHR) domains. USH1C may be involved in protein-protein interaction. Defects in USH1C are the cause of Usher syndrome type 1C (USH1C), als... |