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196

抑制剂 & 化合物

32

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5513	RO-3	P2X Receptor	Membrane transporter/Ion channel; Neuroscience
	RO3 是一种能透过大脑的P2X3和P2X2/3拮抗剂，口服有活性。它对人同型多聚体 P2X3和异型多聚体 P2X2/3受体的 pIC50分别为 5.9 和 7.0。
T26745	BAY 73-1449 BAY-73-1449,BAY73-1449	Others	Others
	BAY 73-1449 是前列环素受体选择性拮抗剂，在人 HEL 细胞和大鼠 DRG 的 cAMP 分析中具有很高的效价，IC50小于 0.1 nM。BAY 73-1449在降血压方面有研究的价值。
T1504	Silodosin 西洛多辛,KAD 3213,KMD 3213	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Silodosin (KAD 3213) 是有选择性的、强效的、口服活性的 α1A-adrenergic receptor 阻滞剂，是一种有效且耐受性良好的试剂，可用于研究 LUTS/BPH。它对 α1A-AR 表现出高度的亲和力，是 α1B-AR 和 α1D-AR 亲和力的 162 和 50 倍。
T6991	Nitroprusside disodium dihydrate 硝普钠二水合物,硝普钠,Sodium Nitroferricyanide(III) Dihydrate,Sodium Nitroprusside Dihydrate	Guanylate cyclase; Autophagy	Autophagy; GPCR/G Protein
	Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) 是一种血管扩张剂，通过在血液中自发释放 NO 发挥作用。它可在谷胱甘肽耗竭的成骨细胞中诱导自噬，用于急性高血压和心力衰竭的研究。
T0703	Flavoxate hydrochloride Flavoxate HCl,盐酸黄酮哌酯,NSC-114649,DW61,Rec-7-0040	AChR	Neuroscience
	Flavoxate hydrochloride (DW61) 是一种毒蕈碱受体 AChR 拮抗剂， IC50为 12.2 μM。
T64006	Lipid-lowering agent-1
	Lipid-lowering agent-1 是有效的降脂剂，能够明显抑制低密度脂蛋白胆固醇 (LDLC) 和促进高密度脂蛋白胆固醇 (HDLC) 产生的药理作用。Lipid-lowering agent-1 能够明显降低高脂饮食大鼠的脂肪。
T8529	WYC-210	Others	Others
	WYC-210 是一种视黄醇类化合物，是 Tazarotene 的衍生物，具有较低的抗癌活性。
T21478	Cromakalim BRL-34915,BRL 34915,(±)-Cromakalim,BRL34915
	Cromakalim, a potassium channel-opening vasodilator, acts on ATP-sensitive potassium channels and so causes membrane hyperpolarization, it can be used to treat hypertension as it will relax vascular smooth muscle to lower blood pressure. The active isomer
T15102	Dexamethasone palmitate 地塞米松棕榈酸酯,DXP	Glucocorticoid Receptor	Endocrinology/Hormones
	Dexamethasone palmitate (DXP) (DXP) 是 Dexamethasone 的前药。Dexamethasone 是糖皮质激素受体激动剂。与Dexamethasone 相比， DXP 对糖皮质激素受体的亲和力低 47 倍。DXP 显示出抗炎活性。
TP2104L	UFP 803 acetate	Neurotensin Receptor	GPCR/G Protein
	UFP 803 acetate 是一种有效的 urotensin-II (UT) 受体配体。 UFP-803 显示较低残留激动剂的活性。
T22316	Doxazosin UK 33274,多沙唑嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Doxazosin (UK 33274) 是选择性的拮抗突触后的α1肾上腺素受体。
T19794	Temafloxacin 替马沙星,Omniflox	Antibiotic	Microbiology/Virology
	Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂，对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。
T20381	Cetyl glycol NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525	Others	Others
	Cetyl glycol (NSC-71525) 有利于金属有机前体的分解、中间体 Co(2+)Fe(3+)-油酸配合物的形成以及纳米颗粒在较低温度下的成核。 Cetyl glycol 是一种可用于化妆品的还原剂。
T63166	LSN3318839 LSN-3318839,LSN 3318839	Glucagon Receptor	GPCR/G Protein
	LSN3318839 是一种有效且可口服的胰高血糖素样肽-1受体（GLP-1R）变构调节剂。LSN3318839可增强GLP-1R的G蛋白偶联信号传导，可用来降低血糖。
T15251	Etebenecid 乙磺舒,Urelim	Others	Others
	Etebenecid (Urelim) 是促尿酸排泄药，能够抑制青霉素自肾小管分泌。
T6728	VUF 10166	5-HT Receptor	GPCR/G Protein; Neuroscience
	VUF 10166 是一种新型的、有效的、竞争性的 5-HT3A 受体拮抗剂，Ki 为 0.04 nM，其对 5-HT3AB 受体的亲和力显着降低。
T6565	Levobetaxolol hydrochloride Betaxon,左旋倍他洛尔,(S)-Betaxolol hydrochloride,AL-1577A,Levobetaxolol HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride) 是 β-肾上腺素能受体抑制剂 (β阻滞剂) 。它具有降低眼压的作用，可用于研究青光眼。
T1423	3-Methylsalicylic acid Hydroxytoluic acid,3-甲基水杨酸,o-Cresotic acid,邻甲基水杨酸	COX	Immunology/Inflammation; Neuroscience
	3-Methylsalicylic acid (o-Cresotic acid) 是水杨酸衍生物，可作用于人血浆，激活纤维蛋白溶解系统，具有显著的纤溶活性。
T29037	UC-781 NSC 675186,UC781,UC 781	Antiviral; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	UC-781 (NSC-675186) 是一种高效且具有选择性的人类免疫缺陷病毒 HIV-1 非核苷类逆转录酶(NNRTI)I抑制剂，C50 值为 5 nM。UC-781 具有抗病毒活性和耐药性。UC-781状态稳定，较低的 PH 或不同温度对其影响较小。
T10000	(±)-Tazifylline	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	(±)-Tazifylline 是一种选择性的长效组胺 H1 受体拮抗剂。 Tazifylline 对 H2 受体、α- 和 β-肾上腺素能受体、5-羟色胺和毒蕈碱受体亚型的亲和力要低得多。
T14298	Rimiducid	Apoptosis; Others; Fatty Acid Synthase	Apoptosis; Metabolism; Others
	Rimiducid 是一种可渗透脂质的他克莫司类似物，是一种二聚剂，通过交联 FKBP 结构域起作用。它将 Caspase 9 自杀开关二聚化并迅速诱导细胞凋亡。
T3978	Linerixibat GSK2330672,Iinerixibat	HBV	Microbiology/Virology
	Linerixibat (GSK2330672) 是高效的、不可吸收的、具有口服活性的顶端钠依赖性胆汁酸转运蛋白 (ASBT) 抑制剂，对人ASBT 的IC50为 42 nM。它是一种降脂剂，具有用于 2 型糖尿病和原发性胆源性胆管炎的研究潜力。
T13140	Umbralisib R-enantiomer TGR-1202 R-enantiomer,RP5264 R-enantiomer	PI3K	PI3K/Akt/mTOR signaling
	Umbralisib R-enantiomer (RP5264 R-enantiomer) 是 PI3K 的δ型抑制剂，是 TGR-1202 活性较低的对映体。Umbralisib R-enantiomer 对δ型 pi3激酶的 IC50，至少比抑制剂对其他 PI3K 亚型(A， β和γ)的 IC50低20倍。
T40229	SR-0813	Epigenetic Reader Domain	Chromatin/Epigenetic
	SR-0813 is a potent and selective inhibitor of the YEATS domain in ENL/AF9. It has an IC 50 of 25 nM and EC 50 of 205 nM for the ENL YEATS domain and an IC 50 of 311 nM and EC 50 of 76 nM (CETSA) for the AF9 YEATS domain. SR-0813 exhibits over 100-fold lower affinity (Kd =3.5 μM) for MAP3K19 compared to ENL YEATS (Kd =30 nM). It can be utilized in acute leukemia research.
T22029	AL 34662	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	AL 34662 是一种具有选择性和高效性的 5-HT2A 受体激动剂，对大鼠和人 5-HT2 受体的IC50 分别为 0.77 nM 和 1.5 nM。AL 34662 还是一种亲和力较低的 α-1D 肾上腺素能激动剂，EC50 值为 0.4 μM。AL 34662 可用于降低眼压。
TQ0271	Falnidamol BIBX 1382	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Falnidamol (BIBX 1382) 是一种具有口服活性的，选择性的 EGFR 酪氨酸激酶抑制剂，IC50 为3 nM。Falnidamol 对 ErbB2 (IC50=3.4 μM) 和其他一系列相关酪氨酸激酶 (IC50>10 μM) 的选择性 >1000倍。Falnidamol 是嘧啶-嘧啶化合物，具有抗癌活性。
T3625	Bempedoic acid ETC1002,ESP-55016,ETC 1002,ETC-1002	ATP Citrate Lyase; AMPK	Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
	Bempedoic acid (ETC1002) 是一种 ATP-柠檬酸裂解酶抑制剂，可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
T11174	(R)-Elagolix 恶拉戈利,NBI-56418	GNRH Receptor	GPCR/G Protein
	(R)-Elagolix (NBI-56418) 是口服具有活性的、选择性高的非肽类促性腺激素释放激素受体短期有效拮抗剂 (KD = 54 pM)。
T2119	Venetoclax GDC-0199,ABT 199,维奈妥拉,ABT-199,ABT199	BCL; Autophagy	Apoptosis; Autophagy
	Venetoclax (ABT-199) 是一种 Bcl-2 抑制剂 (Ki<0.01 nM)，具有高效性、选择性和口服活性。Venetoclax 与 Bcl-xL 和 Bcl-W 的亲和力降低了 3 个数量级（Kis=48/245 nM）。Venetoclax 可以诱导自噬和凋亡。
T7218	Endomorphin 2 内吗啡肽 2	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Endomorphin 2 是一种高亲和力和选择性的 μ-阿片受体激动剂，对 kappa3 结合位点具有合理的亲和力，Ki 为 20 到 30 nM 之间。
T15300	Fluorofenidone AKF-PD	Others	Others
	Fluorofenidone (AKF-PD) 是 AMR69 的类似物，抗纤维化活性与 AMR69相同，但 Fluorofenidone 的毒性更低，半衰期长。它部分通过 PI3K/Akt 信号通路抑制 NADPH 氧化酶和细胞外基质 (ECM) 的沉积，能够减少肾间质纤维化的发生。
T0197	Terazosin hydrochloride 盐酸特拉唑嗪,Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Terazosin hydrochloride (Hytrin) 是一种竞争性和口服活性的 α1-肾上腺素受体拮抗剂，是一种喹唑啉衍生物。它通过舒张血管和打开膀胱来起作用。它可用于良性前列腺增生和高血压的研究。
T9417L	gamma-preprotachykinin amide (72-92) acetate gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)	Others	Others
	gamma-preprotachykinin amide (72-92) acetate 是一种 21 个氨基酸的肽，属于速激肽 (TK) 家族，在其 C 末端序列中包括神经激肽 A (NKA)。它对中枢 NK-2 受体的亲和力高于 NKA；它对 NK-1 受体的亲和力较低，但是，它有效地刺激唾液分泌，这是由 NK-1 受体激活介导的。
T0006	Methylene Blue trihydrate 碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue	Guanylate cyclase; Microtubule Associated; NO Synthase; Parasite; Monoamine Oxidase	Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Methylene Blue trihydrate (Basic blue 9) 是鸟苷酸环化酶，单胺氧化酶 A 和 NO 合酶抑制剂。它是血管加压药，在医疗中通常用作染料。它具有抗伤害感受，抗疟疾，抗抑郁和抗焦虑作用，可用于高铁血红蛋白血症，神经退行性疾病和异环磷酰胺引起的脑病的研究。
T23265	RS 67333 hydrochloride RS 67333 (hydrochloride),RS 67333 HCl,盐酸RS67333	5-HT Receptor	GPCR/G Protein; Neuroscience
	RS 67333 hydrochloride (RO5203648) 是一种有效的、选择性的5-HT4 受体 (5-HT4R) 部分激动剂，在豚鼠纹状体中的 pKi 为 8.7。RS 67333 hydrochloride 对其他几种受体的亲和力较低，包括 5-HT1A、5-HT1D、5-HT2A、5-HT2C、多巴胺 D1、D2 和毒蕈碱 M1-M3 受体。RS 67333 hydrochloride 具有神经保护作用，可用于阿尔茨海默病研究。
T0918	Trimebutine 曲美布汀,Mebutin	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Trimebutine (Mebutin) 是阿片受体激动剂，有抗毒蕈碱活性。它是解痉剂，可调节肠道和结肠运动，并通过抗毒蕈碱和弱μ-阿片受体激动剂作用缓解腹痛。
T0267	Zonisamide AD 810,唑尼沙胺,CI 912	Calcium Channel; Sodium Channel; Carbonic Anhydrase	Membrane transporter/Ion channel; Metabolism
	Zonisamide (AD 810) 是锌酶碳酸酐酶 (carbonic anhydrase) 的有效抑制剂，对人类线粒体同工酶 hCA II 和 hCA V 作用的 Ki 值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性，在癫痫、癫痫发作和帕金森病的研究中具有价值。
T27437	GS-462808 GS462808,GS 462808
	GS-462808 is a late sodium current inhibitor of the cardiac Nav1.5 channel. GS-462808 had lower brain penetration and serendipitously lower activity at the brain isoforms.
T32691	Levamlodipine hydrochloride
	Levamlodipine hydrochloride is a medication used to lower blood pressure and prevent chest pain.
T32692	Levamlodipine hydrobromide Levamlodipine HBr
	Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.
T29999	Amlodipine camsylate
	Amlodipine camsylate is a medication used to lower blood pressure and prevent chest pain.
T29997	Amlodipine adipate CJ11828,CJ 11828,CJ-11828
	Amlodipine adipate is a medication used to lower blood pressure and prevent chest pain.
T0231L3	Amlodipine besylate monohydrate
	Amlodipine besylate monohydrate is a medication used to lower blood pressure and prevent chest pain.
T11018	DHMEQ racemate rel-DHMEQ	NF-κB	NF-κB
	DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.
T32504	L-732531 L732531,L 732531
	L-732531 is a tacrolimus-related immunosuppressant with lower toxicity.
T8663L	Nifenalol
	Nifenalol is an adrenergic beta-blocker with good antiarrhythmic properties. It tends to lower blood pressure and provide protection against angina.
T30001	Amlodipine besylate, (R)-
	Amlodipine besylate, (R)- is a medication used to lower blood pressure and prevent chest pain.
T27418	Glybuzole Desaglybuzole,Sulfamidothiodiazol,Gludiase,Glybuzolum
	Glybuzole is a sulfonamide derivative, it is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.
T30000	Amlodipine hydrobromide Amlodipine HBr
	Amlodipine hydrobromide is a salt of Amlodipine --- a medication used to lower blood pressure and prevent chest pain.
T13442	(R)-BAY1238097	Others	Others
	(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a selective BET inhibitor.

化合物

Cat.No: T5513

Target: P2X Receptor

Cat.No: T26745

Synonym: BAY-73-1449,BAY73-1449

Target: Others

Cat.No: T1504

Synonym: 西洛多辛,KAD 3213,KMD 3213

Target: Adrenergic Receptor

Nitroprusside disodium dihydrate

Cat.No: T6991

Synonym: 硝普钠二水合物,硝普钠,Sodium Nitroferricyanide(III) Dihydrate,Sodium Nitroprusside Dihydrate

Target: Guanylate cyclase, Autophagy

Flavoxate hydrochloride

Cat.No: T0703

Synonym: Flavoxate HCl,盐酸黄酮哌酯,NSC-114649,DW61,Rec-7-0040

Target: AChR

Lipid-lowering agent-1

Cat.No: T64006

Cat.No: T8529

Target: Others

Cat.No: T21478

Synonym: BRL-34915,BRL 34915,(±)-Cromakalim,BRL34915

Dexamethasone palmitate

Cat.No: T15102

Synonym: 地塞米松棕榈酸酯,DXP

Target: Glucocorticoid Receptor

UFP 803 acetate

Cat.No: TP2104L

Target: Neurotensin Receptor

Cat.No: T22316

Synonym: UK 33274,多沙唑嗪

Target: Adrenergic Receptor

Cat.No: T19794

Synonym: 替马沙星,Omniflox

Target: Antibiotic

Cat.No: T20381

Synonym: NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525

Target: Others

Cat.No: T63166

Synonym: LSN-3318839,LSN 3318839

Target: Glucagon Receptor

Cat.No: T15251

Synonym: 乙磺舒,Urelim

Target: Others

Cat.No: T6728

Target: 5-HT Receptor

Levobetaxolol hydrochloride

Cat.No: T6565

Synonym: Betaxon,左旋倍他洛尔,(S)-Betaxolol hydrochloride,AL-1577A,Levobetaxolol HCl

Target: Adrenergic Receptor

3-Methylsalicylic acid

Cat.No: T1423

Synonym: Hydroxytoluic acid,3-甲基水杨酸,o-Cresotic acid,邻甲基水杨酸

Target: COX

Cat.No: T29037

Synonym: NSC 675186,UC781,UC 781

Target: Antiviral, HIV Protease

(±)-Tazifylline

Cat.No: T10000

Target: Histamine Receptor

Cat.No: T14298

Target: Apoptosis, Others, Fatty Acid Synthase

Cat.No: T3978

Synonym: GSK2330672,Iinerixibat

Target: HBV

Umbralisib R-enantiomer

Cat.No: T13140

Synonym: TGR-1202 R-enantiomer,RP5264 R-enantiomer

Target: PI3K

Cat.No: T40229

Target: Epigenetic Reader Domain

Cat.No: T22029

Target: 5-HT Receptor, Adrenergic Receptor

Cat.No: TQ0271

Synonym: BIBX 1382

Target: EGFR

Cat.No: T3625

Synonym: ETC1002,ESP-55016,ETC 1002,ETC-1002

Target: ATP Citrate Lyase, AMPK

Cat.No: T11174

Synonym: 恶拉戈利,NBI-56418

Target: GNRH Receptor

Cat.No: T2119

Synonym: GDC-0199,ABT 199,维奈妥拉,ABT-199,ABT199

Target: BCL, Autophagy

Cat.No: T7218

Synonym: 内吗啡肽 2

Target: Opioid Receptor

Cat.No: T15300

Synonym: AKF-PD

Target: Others

Terazosin hydrochloride

Cat.No: T0197

Synonym: 盐酸特拉唑嗪,Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic

Target: Adrenergic Receptor

gamma-preprotachykinin amide (72-92) acetate

Cat.No: T9417L

Synonym: gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)

Target: Others

Methylene Blue trihydrate

Cat.No: T0006

Synonym: 碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

RS 67333 hydrochloride

Cat.No: T23265

Synonym: RS 67333 (hydrochloride),RS 67333 HCl,盐酸RS67333

Target: 5-HT Receptor

Cat.No: T0918

Synonym: 曲美布汀,Mebutin

Target: Opioid Receptor

Cat.No: T0267

Synonym: AD 810,唑尼沙胺,CI 912

Target: Calcium Channel, Sodium Channel, Carbonic Anhydrase

Cat.No: T27437

Synonym: GS462808,GS 462808

Levamlodipine hydrochloride

Cat.No: T32691

Levamlodipine hydrobromide

Cat.No: T32692

Synonym: Levamlodipine HBr

Amlodipine camsylate

Cat.No: T29999

Amlodipine adipate

Cat.No: T29997

Synonym: CJ11828,CJ 11828,CJ-11828

Amlodipine besylate monohydrate

Cat.No: T0231L3

Cat.No: T11018

Synonym: rel-DHMEQ

Target: NF-κB

Cat.No: T32504

Synonym: L732531,L 732531

Cat.No: T8663L

Amlodipine besylate, (R)-

Cat.No: T30001

Cat.No: T27418

Synonym: Desaglybuzole,Sulfamidothiodiazol,Gludiase,Glybuzolum

Amlodipine hydrobromide

Cat.No: T30000

Synonym: Amlodipine HBr

Cat.No: T13442

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T19056	Safflower yellow Saffron powder,Carthamas yellow,红花黄	Others	Others
	Safflower yellow (Saffron powder) 是提取自植物红花的花中，可用于研究心脑血管疾病。
T6263	Safflower-yellow	Others	Others
	Safflower-yellow 是从植物红花（Carthamus tinctorius）的花中提取的，作为中药已广泛用于治疗心脑血管疾病。
T1134	Clofoctol 叔辛酚氯,氯福克酚	Antibacterial; Antibiotic	Microbiology/Virology
	Clofoctol 是一种抗生素,，可研究革兰氏阳性菌感染。它仅对革兰氏阳性菌起作用, 可渗透入人类肺组织。
T6000	Delta-Tocopherol (+)-DELTA-生育酚,D-DELTA-TOCOPHEROL	Endogenous Metabolite	Metabolism
	Delta-Tocopherol 是维生素 E 的异构体，具有抗氧化活性。
T5735	Methyl deacetylasperulosidate Deacetyl asperulosidic acid methyl ester,6α-Hydroxygeniposide,去乙酰车叶草苷酸甲酯	Others	Others
	Methyl deacetylasperulosidate (6α-Hydroxygeniposide) 是环烯醚萜类化合物，能够降低正常小鼠的血糖水平，对小鼠具有通便作用。
T0254	Probucol DH-581,普罗布考	Virus Protease; ABC; Lipid	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Probucol (DH-581) 是一种抗高脂血症药物，可通过增加 LDL 分解代谢率来降低血液中的胆固醇水平。
T21383	D-Thyroxine Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine	Others	Others
	D-Thyroxine (Dextroxin) 是一种甲状腺激素，对 TSH 的分泌具有抑制作用，可用于研究高胆固醇血症。
TN2230	Soyasaponin Ba 大豆皂苷 BA,大豆皂苷Ba	Others	Others
	Soyasaponin Ba 是一种大豆皂苷，分离自菜豆类，可用作醛糖还原酶抑制剂。
TN1622	Ermanin 堪非醇3,4'-二-O-甲醚	NOS; Influenza Virus; COX; HIV Protease; Antibacterial; Antibiotic	Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Ermanin 是一种从 Tanacetum microphyllum 中分离出来的类黄酮。Ermanin抑制血小板聚集，具有抗结核和抗病毒/细菌特性。Ermanin 可抑制 iNOS 和 COX-2 的表达，从而具有抗炎活性。Ermanin 可能具有抗 HIV-1 活性。Ermanin 在较低浓度下可有效地抑制 Dione juno 幼虫。
T5S1982	Periplocin Periplocoside,杠柳毒苷	Apoptosis; Others	Apoptosis; Others
	Periplocin (Periplocoside) 是从黑龙骨中分离出的一种强心类固醇。它可促进肿瘤细胞凋亡并抑制肿瘤生长。它通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径，具有促进伤口愈合的潜力。
T2698	Asperosaponin VI Akebia saponin D,Asperosaponin Ⅵ,川续断皂苷 VI	Apoptosis; Others; Caspase	Apoptosis; Others; Proteases/Proteasome
	Asperosaponin VI (Akebia saponin D) 是一种来自续断壁的皂苷组分。它通过增加 Bcl-2/Bax 比值，降低活性 caspase-3 表达，以及增强 p-Akt 和 p-CREB，从而抑制缺氧诱导的心肌细胞凋亡。它通过 BMP-2/p38 和 ERK1/2 信号途径诱导成骨细胞分化。
T41095	(E)-3-(4-Methoxyphenyl)acrylic acid (E)-3-(4-甲氧基苯基)丙烯酸	Glucosidase	Metabolism
	(E)-3-(4-Methoxyphenyl)acrylic acid 是从 Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. 的根茎中分离出来的一种小分子化合物。它是一种新型 α-葡萄糖苷酶抑制剂。(E)-3-(4-甲氧基苯基)丙烯酸具有保肝活性、抗失水活性、增强认知效果，并可用于降低血压血糖。
T4000	(±)-Equol Equol,(±)-雌马酚,(R,S)-Equol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。
T1437	D-Panthenol D-泛醇,D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol	Endogenous Metabolite	Metabolism
	D-Panthenol (D-Pantothenyl alcohol) 是 D-pantothenic acid 和胆碱能剂的酒精类似物。D-Panthenol 作为乙酰化反应所必需的辅酶A的前体，参与乙酰胆碱的合成。虽然 D-Panthenol 作用的确切机制尚不清楚，但它可能增强乙酰胆碱的作用。D-Panthenol 作用于胃肠道，增加下肠蠕动。它也适用于局部皮肤，以缓解瘙痒和促进愈合。
T3795	Corilagin	Apoptosis; TLR; Reverse Transcriptase; Antibacterial; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology
	Corilagin 是一种鞣酸，有抑制 RNA 肿瘤病毒逆转录酶的活性。它抑制金黄色葡萄球菌的生长，MIC 为 25 μg/mL。它有抗肿瘤活性，可用于肝癌和卵巢癌。
T4S0145	Corylifol A Corylinin,补骨脂异黄酮A	hCE; STAT; UGT	JAK/STAT signaling; Metabolism; Stem Cells
	Corylifol A (Corylinin) 是补骨脂中的一种天然产物，可抑制IL-6 诱导的STAT3激活和磷酸化，IC50值为0.81 μM。
T4877	L-Homocystine	Endogenous Metabolite	Metabolism
	L-Homocystine 是一种 L-homocysteine 的氧化物。其中 L-homocysteine 是抗血栓因子、血管舒张损害剂、促炎因子，也是研究心血管疾病发生机制的内质网应激反应的诱导剂。
T5S0106	Peimisine 贝母辛,Ebeiensine	RAAS; AChR	Endocrinology/Hormones; Neuroscience
	Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体，抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放，促进一氧化氮释放，可舒张气管平滑肌，有平喘作用。
T0256	Citric acid trilithium salt tetrahydrate Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate	Dehydrogenase; GSK-3; HIF/HIF Prolyl-Hydroxylase; Antibacterial; GluR	Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
	Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) 是一种用于治疗精神疾病的药物。它也是一种医药和建筑材料, 可用于氨基酸定量分析时的梯度洗脱。
TN4974	Scutebata B	Others	Others
	Scutebata B inhibited NO production efficiently with IC50 values of lower than 50 μM.
TN2193	Scutebarbatine W	Others	Others
	Scutebarbatine W can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation.
TN2194	Scutebarbatine X	Others	Others
	Scutebarbatine X can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation.
TN3260	8(14),15-Isopimaradien-3-ol	Calcium Channel; Antifection	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	ent-8(14),15-pimaradien-3beta-ol (8(14),15-Isopimaradien-3-ol) can induce vascular relaxation. It displays high antibacterial activities (MIC values lower than 10 microg /mL for most pathogens).
TN5448	Steppogenin Norartocarpanone
	Steppogenin exhibits significant tyrosinase inhibition activity, ;it also shows strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), a well-known tyrosinase inhibitor.
TN1242	3,3'-Di-O-methylellagic acid 3,8-Di-O-methylellagic acid,3,3'-O-二甲基鞣花酸	Others; TNF; Antifection	Apoptosis; Microbiology/Virology; Others
	3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and tumoural-alpha necrose factor
T13756	Liquiritigenin-7-apiosylglucoside 芹糖新甘草苷,Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside	Others	Others
	Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside is a flavonoid isolated from the roots of Glycyrrhiza, has weaker cytotoxicity against several tumor cells and normal cells.
TMA0127	Ficusin A	transporter; PPAR	DNA Damage/DNA Repair; Metabolism
	Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPARγ expression and improve the transl
T82339	Gangliotetraose Gg4
	Gangliotetraose（Gg4）是一种含有GM1及其唾液酸化衍生物的四糖。它能促进分化神经元核内Ca2+的外流，进而降低核内Ca2+浓度。Gg4参与调节神经元的可塑性、修复过程以及大脑中神经营养素的释放。
T83597	(+)-Menthyl acetate
	(+)-Menthyl acetate是一种从Cunila angustifolia Benth精油中分离得到的化学化合物。它对MCF-7细胞株具有较高的选择性，其半抑制浓度（IC50）为34.0 μg/mL，而对SK-Mel-28细胞株的选择性较低，IC50为279.9 μg/mL，并且对A549细胞没有致死作用。
T79975	Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside	HBV	Microbiology/Virology
	Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside（化合物1）是一种具有抗HBV活性的木脂素类化合物。该化合物对HBV表面抗原（HBsAg）的IC50为0.58 mM，而对HBV e抗原（HBeAg）的IC50 > 2.4 mM。其可从八角茴香中提取分离。
T82031	Isoguaiacin
	Isoguaiacin为一种天然产物，具有复杂的多环化合物结构，广泛应用于生物医药研究领域。
TN4223	Homopterocarpin	Antifection	Microbiology/Virology
	Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property

天然产物

Safflower yellow

Cat.No: T19056

Synonym: Saffron powder,Carthamas yellow,红花黄

Target: Others

Safflower-yellow

Cat.No: T6263

Target: Others

Cat.No: T1134

Synonym: 叔辛酚氯,氯福克酚

Target: Antibacterial, Antibiotic

Delta-Tocopherol

Cat.No: T6000

Synonym: (+)-DELTA-生育酚,D-DELTA-TOCOPHEROL

Target: Endogenous Metabolite

Methyl deacetylasperulosidate

Cat.No: T5735

Synonym: Deacetyl asperulosidic acid methyl ester,6α-Hydroxygeniposide,去乙酰车叶草苷酸甲酯

Target: Others

Cat.No: T0254

Synonym: DH-581,普罗布考

Target: Virus Protease, ABC, Lipid

Cat.No: T21383

Synonym: Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine

Target: Others

Cat.No: TN2230

Synonym: 大豆皂苷 BA,大豆皂苷Ba

Target: Others

Cat.No: TN1622

Synonym: 堪非醇3,4'-二-O-甲醚

Target: NOS, Influenza Virus, COX, HIV Protease, Antibacterial, Antibiotic

Cat.No: T5S1982

Synonym: Periplocoside,杠柳毒苷

Target: Apoptosis, Others

Asperosaponin VI

Cat.No: T2698

Synonym: Akebia saponin D,Asperosaponin Ⅵ,川续断皂苷 VI

Target: Apoptosis, Others, Caspase

(E)-3-(4-Methoxyphenyl)acrylic acid

Cat.No: T41095

Synonym: (E)-3-(4-甲氧基苯基)丙烯酸

Target: Glucosidase

Cat.No: T4000

Synonym: Equol,(±)-雌马酚,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Cat.No: T1437

Synonym: D-泛醇,D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol

Target: Endogenous Metabolite

Cat.No: T3795

Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy

Cat.No: T4S0145

Synonym: Corylinin,补骨脂异黄酮A

Target: hCE, STAT, UGT

Cat.No: T4877

Target: Endogenous Metabolite

Cat.No: T5S0106

Synonym: 贝母辛,Ebeiensine

Target: RAAS, AChR

Citric acid trilithium salt tetrahydrate

Cat.No: T0256

Synonym: Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate

Target: Dehydrogenase, GSK-3, HIF/HIF Prolyl-Hydroxylase, Antibacterial, GluR

Cat.No: TN4974

Target: Others

Scutebarbatine W

Cat.No: TN2193

Target: Others

Scutebarbatine X

Cat.No: TN2194

Target: Others

8(14),15-Isopimaradien-3-ol

Cat.No: TN3260

Target: Calcium Channel, Antifection

Cat.No: TN5448

Synonym: Norartocarpanone

3,3'-Di-O-methylellagic acid

Cat.No: TN1242

Synonym: 3,8-Di-O-methylellagic acid,3,3'-O-二甲基鞣花酸

Target: Others, TNF, Antifection

Liquiritigenin-7-apiosylglucoside

Cat.No: T13756

Synonym: 芹糖新甘草苷,Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside

Target: Others

Cat.No: TMA0127

Target: transporter, PPAR

Gangliotetraose

Cat.No: T82339

Synonym: Gg4

(+)-Menthyl acetate

Cat.No: T83597

Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside

Cat.No: T79975

Target: HBV

Cat.No: T82031

Homopterocarpin

Cat.No: TN4223

Target: Antifection

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