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248

抑制剂 & 化合物

111

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1527	CEF8, Influenza Virus NP (383-391) CEF8, Influenza Virus NP 383-391	Others	Others
	CEF8, Influenza Virus NP (383-391) 是一种甲型流感病毒核蛋白，含有 383-391 残基，是甲型流感病毒核蛋白中重要的 HLA-B*2705 限制性表位，与细胞毒性 T 淋巴细胞介导的免疫逃逸有关。
TP1735L	Influenza HA 126-138 acetate Influenza HA 126-138 acetate(207349-63-1 free base)	Others	Others
	Influenza HA 126-138 acetate 是一种流感病毒血凝素 (HA) 肽乙酸盐，包含氨基酸 126-138。它诱导胸腺和外周 T 细胞凋亡。
T38719L	Influenza HA (110-119) acetate	Others	Others
	Influenza HA (110-119) acetate 是流感病毒血凝素的 110-119 片段，可刺激 Treg 细胞增殖。
T72037	Anti-Influenza agent 4	Influenza Virus	Microbiology/Virology
	Anti-Influenza agent 4 是一种有效且具有选择性的流感病毒抑制剂，对A/Parma 和 A/Roma 毒株具有抑制作用， EC50 分别为 62 nM 和150 nM。
T39292	NS2 (114-121), Influenza NS2 (114-121), Influenza
	NS2 (114-121), Influenza, is a fragment derived from the nonstructural protein 2 (NS2) of the influenza virus. This compound serves as an epitope for influenza research and can be utilized to study the CD8+ cytotoxic T lymphocyte (CTL) in antiviral immune responses.
TP1646	Influenza NP (147-155) Influenza NP 147-155
	This peptide is a H-2Kd-restricted epitope from Influenza nucleoprotein (147-155).
TP1735	Influenza HA (126-138) Influenza HA 126-138
	Influenza HA (126-138) is a peptide derived from the hemagglutinin (HA) protein of the influenza virus. It consists of amino acids 126-138 and has the ability to induce apoptosis in both thymic and peripheral T-cells.
TP1517	Influenza HA (518-526) Influenza HA 518-526
	Influenza HA (518-526) is an immunodominant epitope in H2d mice after flu virus infection.
TP1854	Influenza HA (307-319) Influenza HA 307-319
	Influenza Hemagglutinin is an HLA-DRB 0101-restricted epitope from influenza hemagglutinin (307-319).
TP1596	CEF7, Influenza Virus NP (380-388) CEF7, Influenza Virus NP 380-388
	HLA-B08 restricted influenza* virus nucleoprotein epitope.
TP1717	CEF1, Influenza Matrix Protein M1 (58-66) CEF1, Influenza Matrix Protein M1 58-66
	CEF1, Influenza Matrix Protein M1 (58-66) is an epitope derived from the matrix protein of the influenza A virus.GILGFVFTL is a HLA-A2-restricted epitope from influenza matrix M1 protein.
T38719	Influenza HA (110-119)
	Influenza HA (110-119) refers to a specific fragment (110-119) derived from the hemagglutinin protein of the influenza virus. This fragment has the ability to induce the proliferation of Treg cells.
T39778	Influenza A virus-IN-1
	Influenza A virus-IN-1, a dihydropyrrolidones derivative, is a highly effective inhibitor of various subtypes of influenza A virus (IAV) with IC 50 values ranging from 3.11 μM to 7.13 μM. It effectively suppresses IAV replication and enhances the expression of key antiviral cytokines, such as IFN-β, and the antiviral protein MxA.
T38687	Influenza Matrix Protein (61-72)
	Influenza Matrix Protein (61-72) is a peptide derived from the matrix protein of influenza viruses and encompasses amino acids 61-72. This specific epitope, Influenza Matrix Protein (61-72), has the ability to elicit a CD4+ T-cell response.
TP1867	PA (224-233), Influenza
	PA (224-233), Influenza is a 10-aa peptide, which is a fragment of polymerase 2 protein in Influenza a virus.
T22868	Influenza A virus fragment	Others	Others
	Influenza A virus fragment has the RNA sequence of Leu-Lys-Phe-Ala-Phe-Ser-Met-Met.
TP1632	Influenza NP (147-155) (TFA)
	This peptide is a H2-Db-restricted epitope from Influenza nucleoprotein (147-155).
T22838	hemagglutinin (332-340) [Influenza A virus]	Others	Others
	Influenza hemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. Influenza hemagglutinin proteins bind to cells w
T9231	Mbx2329	Antiviral	Immunology/Inflammation
	MBX2329 是一种流感病毒抑制剂，能特异性地抑制血凝素介导的病毒进入，HIV/HA(H5) 的 IC90值为8.6 μM。它能够有效地抑制多种甲型流感病毒。
T12818	S119-8	Influenza Virus	Microbiology/Virology
	S119-8 是一种广谱甲型和乙型流感病毒抑制剂，抑制多种乙型流感病毒和耐奥司他韦的甲型流感病毒。
T38239	2'-Deoxy-2'-fluorouridine
	2'-Deoxy-2'-fluorouridine 是合成抗流感病毒试剂的中间体。
T8354	Triazavirin	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Triazavirin 是一种核酸的核苷类似物和抗病毒剂，通过抑制病毒 RNA 和 DNA 的合成以及基因组片段的复制而起作用。在流感传播阶段，它可作为保护剂。
TP2232	hemagglutinin precursor (114-122) amide [Influenza A virus]	Others	Others
	Partial antigenic glycoprotein
TP1644	Influenza A NP(366-374) Strain A/PR/8/35
	This peptide is an H2-Db-restricted epitope from the Influenza A/PR/8/34 nucleoprotein.
T38236	2′-Deoxy-2′-fluoroguanosine	Nucleoside Antimetabolite/Analog; Influenza Virus	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	2′-Deoxy-2′-fluoroguanosine 是一种核苷类似物，有效抑制流感病毒，抑制A 型和B 型流感病毒的EC90值 <0.35 μM。2′-Deoxy-2′-fluoroguanosine 显著抑制流感病毒在上呼吸道中的复制，从而改善鼻腔炎症和发烧。
T8793	CBS1117	Influenza Virus	Microbiology/Virology
	CBS1117 是一种病毒进入抑制剂，对甲型流感病毒 A/Puerto Rico/8/34 的 IC50为 70 nM。它干扰血凝素介导的融合过程。
T9124	Laninamivir octanoate 辛酸拉尼米韦,CS-8958	Influenza Virus	Microbiology/Virology
	Laninamivir octanoate (CS-8958) 是一种长效流感神经氨酸酶抑制剂，是Laninamivir 的前药，具有优异的抗流感病毒活性。
T12077	ML303	Influenza Virus	Microbiology/Virology
	ML303 是吡唑并吡啶流感病毒非结构蛋白 1 的一种拮抗剂，IC90值为 155 nM。它对流感病毒H1N1亚型的EC50值为0.7 μM。
T12526	PP7	Influenza Virus	Microbiology/Virology
	PP7 是一种PB1-PB2互作抑制剂，IC50为 8.6 μM。PB1-PB2 抑制病毒聚合酶的活性，IC50为9.5 μM。它对甲型流感病毒 A 包括 (H1N1)pdm09 (EC50=1.4 μM)，A(H7N9)，A(H9N2) 亚型具有抗病毒活性。
T14495	Baloxavir Baloxavir acid,S-033447	Influenza Virus	Microbiology/Virology
	Baloxavir (S-033447) 是衍生自前药 Baloxavir marboxil，是流感病毒聚合酶 PA 亚基的一流帽依赖性核酸内切酶抑制剂。它抑制病毒 RNA 的转录和复制，具有强大的抗病毒活性。
T4027	KIN1148	Influenza Virus	Microbiology/Virology
	KIN1148 是一种新型小分子佐剂，是IRF3激动剂，用于增强流感疫苗效率。
T8555	Neuraminidase-IN-1 Novel NA Inhibitor,Compound Y-1	Others; Influenza Virus	Microbiology/Virology; Others
	Neuraminidase-IN-1 (Compound Y-1) 是一种神经氨酸酶抑制剂，其IC50值为 0.21 μM，具有抗H1N1流感病毒的活性。
T12953	Sodium copper chlorophyllin B	Influenza Virus; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Sodium copper chlorophyllin B 对流感病毒和HIV 有抗病毒活性，IC50s 值都是 50 到 100 μM。
T6532	Hesperadin	Influenza Virus; Parasite; Aurora Kinase; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Microbiology/Virology
	Hesperadin 是 Aurora A 和 B 的 ATP 竞争性吲哚酮抑制剂，抑制 Aurora B 的 IC50值为250nM。它通过阻断核分裂和胞质分裂而抑制布鲁氏锥虫的生长。它也是一种广谱流感抗病毒剂。
T2529	Zanamivir 扎那米韦,GG167	Influenza Virus; Antibiotic	Microbiology/Virology
	Zanamivir (GG167) 是神经氨酸酶抑制剂，对于流感病毒 A 和B 的IC50值分别为0.95 nM 和2.7 nM。
T4377	Pimodivir VX-787	Influenza Virus	Microbiology/Virology
	Pimodivir (VX-787) 是一种通过口服的甲型流感病毒聚合酶抑制剂，与病毒 PB2 亚基相互作用。
T83046	Anti-Influenza agent 5	Influenza Virus	Microbiology/Virology
	Anti-Influenza agent 5 (Compound IIB-2)为查耳酮类衍生物，具有抑制流感病毒核输出的活性。该化合物能有效抑制对Oseltamivir具有耐药性的病毒株，主要通过阻断流感病毒核蛋白输出作用来抑制病毒复制。
T60697	Influenza virus-IN-1
	Influenza virus-IN-1 (compound 14) 具有抗甲型流感病毒活性，它是甲型流感病毒的有效抑制剂，其CC50值 >200 μM，EC50值为 2.46 μM。Influenza virus-IN-1 对 PAN 核酸内切酶显示出浓度依赖性的抑制活性 (EC50 = 312.36 nM)。
T6195	Baloxavir marboxil S-033188	Influenza Virus	Microbiology/Virology
	Baloxavir marboxil (S-033188) 是一种新型的帽依赖性核酸内切酶抑制剂，用于治疗甲型和乙型流感病毒感染。
T60810	Influenza virus-IN-2
	Influenza virus-IN-2 (compound 19) 具有抗甲型流感病毒活性，是有效的流感病毒抑制剂，CC50值为 150.85 μM，EC50值为 2.58 μM,。Influenza virus-IN-2 浓度依赖性的抑制 PAN 核酸内切酶，EC50为 489.39 nM。
T61557	Influenza A virus-IN-4
	Influenza A virus-IN-4 (compound 23b), a derivative of Oseltamivir, is a highly effective neuraminidase inhibitor. It exerts potent inhibitory effects on influenza viruses [1].
T62197	Influenza virus-IN-4
	Influenza virus-IN-4 (compound 11e) 是一种流感病毒神经氨酸酶的有效抑制剂，能够作用于 H5N1 (IC50: 3.4 μM)、H5N2 (IC50: 0.094 μM)、H5N6 (IC50: 0.79 μM)、H5N8 (IC50: 0.077 μM)。Influenza virus-IN-4 能够抑制 NA（神经氨酸酶），并具有低细胞毒性(CC50>200 μM)。Influenza virus-IN-4 在1500 mg/kg 时，对小鼠没有明显的毒性。
T62216	Influenza virus-IN-5
	Influenza virus-IN-5 (Compound 5f) 是一种流感病毒血球凝集素 (hemagglutinin (HA)) 抑制剂，能够作用于 A/H3N2 病毒 (EC50: 1 nM)。
T72450	Influenza virus-IN-6	Influenza Virus	Microbiology/Virology
	Influenza virus-IN-6 (Compound 35) 是一种针对流感病毒聚合酶酸性蛋白亚基内切酶N端结构域(PAN)的高效抑制剂，展现出0.20 μM的IC50值。
T0244	Tilorone dihydrochloride	Influenza Virus; HIF/HIF Prolyl-Hydroxylase; IFNAR	Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Tilorone dihydrochloride 是一种具有口服活性的干扰素诱导剂，具有抗肿瘤和抗炎作用。
T75166	Influenza virus-IN-7
	Influenza virus-IN-7 (Example 16) 是一种口服活性的帽依赖性核酸内切酶抑制剂，适用于流感病毒感染疾病的研究。
T62837	Influenza virus-IN-3
	Influenza virus-IN-3 (compound 9) 是一种选择性流感病毒的有效抑制剂，能够作用于 H5N1 (IC50: 0.88 μM)、H5N2 (IC50: 0.10 μM)、H5N6 (IC50: 5.5 μM)、H5N8 (IC50: 0.51 μM)。Influenza virus-IN-3 具有抗病毒和 NA (神经氨酸酶) 抑制作用，且细胞毒性低 (CC50>200 μM)。
T3257	UNC0638	Influenza Virus; Histone Methyltransferase; Autophagy	Autophagy; Chromatin/Epigenetic; Microbiology/Virology
	UNC0638 是 β-蛋白赖氨酸甲基转移酶 G9a 和 GLP 的抑制剂，选择性抑制表观遗传和非表观遗传靶标。
T60778	Anti-Influenza agent 3
	Anti-Influenza agent 3 (compound 11h) 是有效的抗流感药物，对 MDCK 上皮细胞显示出低细胞毒性。Anti-Influenza agent 3 抑制 M2 WT 和 S31N 离子通道的传导性。Anti-Influenza agent 3 对 A/HK/68 (H3N2, M2-WT) 菌株的 EC50值为 3.29 μM，对 A/WSN/33 (H1N1, M2-S31N) 菌株的 EC50值为 2.45 μM。
T6110	YM-201636	Influenza Virus; PI3K; Autophagy	Autophagy; Microbiology/Virology; PI3K/Akt/mTOR signaling
	YM201636 是是一种特异性 PIKfyve 抑制剂，IC50值为 33 nM，对 p110α的IC50为 3.3 μM。它还可抑制逆转录病毒复制。

化合物

CEF8, Influenza Virus NP (383-391)

Cat.No: TP1527

Synonym: CEF8, Influenza Virus NP 383-391

Target: Others

Influenza HA 126-138 acetate

Cat.No: TP1735L

Synonym: Influenza HA 126-138 acetate(207349-63-1 free base)

Target: Others

Influenza HA (110-119) acetate

Cat.No: T38719L

Target: Others

Anti-Influenza agent 4

Cat.No: T72037

Target: Influenza Virus

NS2 (114-121), Influenza

Cat.No: T39292

Synonym: NS2 (114-121), Influenza

Influenza NP (147-155)

Cat.No: TP1646

Synonym: Influenza NP 147-155

Influenza HA (126-138)

Cat.No: TP1735

Synonym: Influenza HA 126-138

Influenza HA (518-526)

Cat.No: TP1517

Synonym: Influenza HA 518-526

Influenza HA (307-319)

Cat.No: TP1854

Synonym: Influenza HA 307-319

CEF7, Influenza Virus NP (380-388)

Cat.No: TP1596

Synonym: CEF7, Influenza Virus NP 380-388

CEF1, Influenza Matrix Protein M1 (58-66)

Cat.No: TP1717

Synonym: CEF1, Influenza Matrix Protein M1 58-66

Influenza HA (110-119)

Cat.No: T38719

Influenza A virus-IN-1

Cat.No: T39778

Influenza Matrix Protein (61-72)

Cat.No: T38687

PA (224-233), Influenza

Cat.No: TP1867

Influenza A virus fragment

Cat.No: T22868

Target: Others

Influenza NP (147-155) (TFA)

Cat.No: TP1632

hemagglutinin (332-340) [Influenza A virus]

Cat.No: T22838

Target: Others

Cat.No: T9231

Target: Antiviral

Cat.No: T12818

Target: Influenza Virus

2'-Deoxy-2'-fluorouridine

Cat.No: T38239

Cat.No: T8354

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis

hemagglutinin precursor (114-122) amide [Influenza A virus]

Cat.No: TP2232

Target: Others

Influenza A NP(366-374) Strain A/PR/8/35

Cat.No: TP1644

2′-Deoxy-2′-fluoroguanosine

Cat.No: T38236

Target: Nucleoside Antimetabolite/Analog, Influenza Virus

Cat.No: T8793

Target: Influenza Virus

Laninamivir octanoate

Cat.No: T9124

Synonym: 辛酸拉尼米韦,CS-8958

Target: Influenza Virus

Cat.No: T12077

Target: Influenza Virus

Cat.No: T12526

Target: Influenza Virus

Cat.No: T14495

Synonym: Baloxavir acid,S-033447

Target: Influenza Virus

Cat.No: T4027

Target: Influenza Virus

Neuraminidase-IN-1

Cat.No: T8555

Synonym: Novel NA Inhibitor,Compound Y-1

Target: Others, Influenza Virus

Sodium copper chlorophyllin B

Cat.No: T12953

Target: Influenza Virus, HIV Protease

Cat.No: T6532

Target: Influenza Virus, Parasite, Aurora Kinase, Autophagy

Cat.No: T2529

Synonym: 扎那米韦,GG167

Target: Influenza Virus, Antibiotic

Cat.No: T4377

Synonym: VX-787

Target: Influenza Virus

Anti-Influenza agent 5

Cat.No: T83046

Target: Influenza Virus

Influenza virus-IN-1

Cat.No: T60697

Baloxavir marboxil

Cat.No: T6195

Synonym: S-033188

Target: Influenza Virus

Influenza virus-IN-2

Cat.No: T60810

Influenza A virus-IN-4

Cat.No: T61557

Influenza virus-IN-4

Cat.No: T62197

Influenza virus-IN-5

Cat.No: T62216

Influenza virus-IN-6

Cat.No: T72450

Target: Influenza Virus

Tilorone dihydrochloride

Cat.No: T0244

Target: Influenza Virus, HIF/HIF Prolyl-Hydroxylase, IFNAR

Influenza virus-IN-7

Cat.No: T75166

Influenza virus-IN-3

Cat.No: T62837

Cat.No: T3257

Target: Influenza Virus, Histone Methyltransferase, Autophagy

Anti-Influenza agent 3

Cat.No: T60778

Cat.No: T6110

Target: Influenza Virus, PI3K, Autophagy

Cat. No.	Product Name	Target	Signaling Pathways
T2945	Germacrone	P450; Antiviral; Influenza Virus	Immunology/Inflammation; Metabolism; Microbiology/Virology
	Germacrone 提取自姜黄，具有抗炎、抗雄激素和抗病毒活性。它还通过促进细胞凋亡来抑制胶质瘤细胞的增殖。
T0775	Coumarin	Factor Xa; Influenza Virus	Metabolism; Microbiology/Virology
	Coumarin 是中国北沙参中的一种主要生物活性成分，具有抗癌、抗炎和抗病毒等活性。它作为几种抗凝剂的前体具有临床价值，尤其是华法林。
T5S1708	Dendrobine	Others; Influenza Virus	Microbiology/Virology; Others
	Dendrobine 是从石斛中分离的一种生物碱，对甲型流感病毒具有抗病毒活性。
T3905	Isomangiferin 芒果	Free radical scavengers; Antiviral; Influenza Virus	Immunology/Inflammation; Microbiology/Virology; oxidation-reduction
	Isomangiferin 是一种天然产物，具有抗病毒的作用。它还具有抗氧化和自由基清除活性。
TN2331	Eleutheroside B1 刺五加苷B1	Influenza Virus	Microbiology/Virology
	Eleutheroside B1是具有广谱抗人流感病毒的一种香豆素。它抑制多种趋化因子基因和流感病毒核蛋白基因的 mRNA 表达。它具有抗病毒、抗流感和抗炎活性，且细胞毒性小。
T7602	Theaflavin	Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Theaflavin 是在红茶中发现的一种多酚类黄酮，具有如抗氧化、抗癌、抗炎和抗病毒多种生物活性。
T2957	Arctigenin 牛蒡苷元,牛蒡子苷元,(-)-Arctigenin	Apoptosis; MMP; Influenza Virus; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Arctigenin ((-)-Arctigenin) 是一种存在于牛蒡中的木脂素，具有抗氧化、抗肿瘤、抗炎和抗病毒活性。它可研究代谢紊乱和中枢神经系统功能障碍。
T2S0257	Dehydroandrographolide succinate	Others; Influenza Virus	Microbiology/Virology; Others
	Dehydroandrographolide succinate 是从中药穿心莲中提取的一种天然产物，具有免疫刺激、抗感染和抗炎作用，有潜力研究病毒性肺炎和病毒性上呼吸道感染。
T2738	Dehydroandrographolide	NOS; Influenza Virus	Immunology/Inflammation; Microbiology/Virology
	Dehydroandrographolide 是从草药穿心莲中提取的一种天然产物。它通过使 iNOS 失活来降低 LPS 诱导的急性肺损伤中的氧化应激，有抗感染活性。
TN1103	Diphyllin 山荷叶素,二叶草素	ATPase; Proton pump; Influenza Virus; HIV Protease	Membrane transporter/Ion channel; Microbiology/Virology; Proteases/Proteasome
	Diphyllin 是一种从Justicia procumbens 中分离的芳基萘木脂素，是HIV-1的有效抑制剂，IC50 为 0.38 μM。它是V-ATPase 抑制剂，IC50值为 17 nM，可抑制人破骨细胞中的溶酶体酸化。它抑制NO 产生，IC50值为 50 μM ，具有抗癌和抗炎活性。
T8187	Tetrahydroepiberberine	Others; Influenza Virus; Antifungal	Microbiology/Virology; Others
	Tetrahydroepiberberine 是从Corydalis impatiens(Pall) 中分离得到的一种异喹啉生物碱，具有抗真菌和选择性抑制 PI-3 病毒活性的作用。
T8286	Harringtonine 三尖杉酯碱,三尖杉脂碱	Others; Influenza Virus	Microbiology/Virology; Others
	Harringtonine 是一种天然的 Cephalotaxus 生物碱，可抑制蛋白质合成，有抗基孔肯雅病毒活性，EC50为 0.24 μM。
T2854	Phillyrin Forsythin,连翘苷	P450; Influenza Virus; AMPK	Chromatin/Epigenetic; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Phillyrin (Forsythin) 是从连翘中分离出来的一种天然产物，具有抗甲型流感病毒的活性，以及抗菌和消炎作用。
TQ0180	Chebulagic acid	SARS-CoV; Influenza Virus; Lipoxygenase; COX	Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的一种 COX-LOX 双重抑制剂，有抗炎和抗感染作用。它抑制 SARS-CoV-2病毒的复制，EC50值为 9.76 μM。它还是 M2(S31N)抑制剂和抗流感病毒剂。
T3S1852	Cephaeline hydrochloride	Others; Virus Protease; Influenza Virus	Microbiology/Virology; Others
	Cephaeline hydrochloride 是 Indian Ipecac 中的一种酚类生物碱。它有效抑制病毒 ZIKV 和 EBOV 感染。
T6S0232	Eriodictyol 圣草酚,Huazhongilexone	Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物，具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 18 nM。它可诱导Nrf2信号通路。
T4S1335	Daphnoretin Dephnoretin,西瑞香素,Thymelol	Influenza Virus; Caspase; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	Daphnoretin (Thymelol) 是从了哥王中提取得到的一种天然产物，具有抗癌和抗病毒活性。它通过在 G2/M 期连续阻断细胞并激活 caspase-3 通路导致 HOS 细胞死亡。
T2212	Geniposide 栀子苷,京尼平甙	Beta Amyloid; Influenza Virus	Microbiology/Virology; Neuroscience
	Geniposide 是从栀子花中提取的一种环烯醚萜甙，具有如神经保护、抗糖尿病、抗增殖和抗氧化多种生物活性。它可调节 Nrf2 易位。
T6677	Sophocarpine	ERK; p38 MAPK; NF-κB; TLR; COX; HER; JNK; STAT	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Sophocarpine 是一种从传统草药苦参中提取的重要生物碱。苦参具有抗病毒、抗肿瘤和抗炎等多种药理作用。它通过多种机制显著抑制癌细胞的生长，具有抗肿瘤活性。
T10835	Cletoquine Desethylhydroxychloroquine	Parasite; Antifection	Microbiology/Virology
	Cletoquine 是 Hydroxychloroquine 的主要活性代谢物。 Cletoquine 具有对抗基孔肯雅病毒 (CHIKV) 的能力。 Cletoquine 具有抗疟作用，并具有治疗自身免疫性疾病的潜力。
T2858	Baicalein 5,6,7-Trihydroxyflavone,黄芩素,黄芩黄素	Ferroptosis; Influenza Virus; ROS; Xanthine Oxidase	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Baicalein (5,6,7-Trihydroxyflavone) 是一种黄嘌呤氧化酶抑制剂，其IC50值为 3.12 μM。
T13229	Tunicamycin	Influenza Virus; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Tunicamycin 是一种抗生素的混合物，通过阻断 GlcNAc 磷酸转移酶 (GPT)，抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性，还具有抗细菌、抗真菌和抗病毒活性。
T2942	Psoralen Ficusin,Furocoumarin,补骨脂素,psoralene	Apoptosis; Influenza Virus; HIV Protease; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Psoralen (Ficusin) 是从补骨脂种子中提取的一种香豆素。它具有如抗癌、抗氧化、抗抑郁、抗癌、抗菌、抗病毒等多种生物学特性。
T0681	Rifampicin Rifamycin AMP,利福平,Rimactane,Rifampin	Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic; Antifection	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifampicin (Rifamycin AMP) 是广谱抗生素，可抵抗细菌病原体以及具有抗流感病毒活性。
TN1480	Cephaeline 吐根鹼,吐根酚碱	Virus Protease; Influenza Virus; HIF	Angiogenesis; Chromatin/Epigenetic; Microbiology/Virology
	Cephaeline 对受保护的原代 CLL 细胞具有高度活性（相对 IC50 为 35nM），并通过抑制 HIF-1α± 和扰乱细胞内氧化还原稳态发挥作用。
T3366	Cephalotaxine ZINC19795976,三尖杉碱,(-)-Cephalotaxine,Cephalotaxlen	Antiviral; Influenza Virus	Immunology/Inflammation; Microbiology/Virology
	Cephalotaxine (ZINC19795976) 是从头孢紫杉中分离得到的一种生物碱，具有抗白血病和抗病毒活性，如抗 Zika 病毒。
T3342	Xanthohumol	Apoptosis; Others; Influenza Virus; COX; Acyltransferase; HSV	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; Others
	Xanthohumol 是从啤酒花中分离到的黄酮类化合物，可抑制 COX-1 和 COX-2 活性，具有抗肿瘤，抗血管生成的作用，还具有抗多种病毒的活性。
T3341	Elemicin Elemicine,3,4,5-trimethoxyallylbenzene,榄香素	Influenza Virus; 5-HT Receptor; Stearoyl-CoA Desaturase (SCD)	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Elemicin (Elemicine) 是广泛分布于许多草药和香料中的一种烯基苯。它是芳香族食品中的主要成分之一，具有抗微生物，抗氧化剂和抗病毒活性，有遗传毒性和致癌性。它通过代谢激活抑制硬脂酰辅酶 A 去饱和酶 1。
T2998	Dihydromyricetin Ampelopsin,Ampeloptin,二氢杨梅素	Influenza Virus; GABA Receptor; DNA/RNA Synthesis; mTOR; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Dihydromyricetin (Ampelopsin) 是一种来自 Ampelopsis Grossedentata 的天然抗氧化剂类黄酮，是二氢嘧啶酶抑制剂，IC50 为 48 μM。它通过抑制mTOR 信号从而激活自噬。它还是流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 22 μM。
T4S1114	Dryocrassin ABBA 东北贯众素,Dryocrassin	Influenza Virus; Antibacterial	Microbiology/Virology
	Dryocrassin ABBA (Dryocrassin) 是一种从苦参中提取的黄酮类天然产物，具有抗病毒和抗菌活性。它抑制树突状细胞的免疫刺激功能，延长同种异体皮肤移植成活率。
T2844	Hyperoside Quercetin 3-galactoside,金丝桃甙,金丝桃苷,Hyperin	Others; Influenza Virus; Antifungal	Microbiology/Virology; Others
	Hyperoside (Hyperin) 是一种从Camptotheca acuminate 提取的黄酮，具有多种生物活性，如心肌保护、抗氧化还原和抗炎活性。
T2898	Andrographolide Andrographis,穿心莲内酯	SARS-CoV; Influenza Virus; NF-κB; Autophagy	Autophagy; Microbiology/Virology; NF-κB
	Andrographolide (Andrographis) 是 NF-κB 的不可逆拮抗剂，具有抗病毒、抗炎和抗血小板聚集活性和潜在的抗肿瘤作用。
T3007	Spermine Gerontine,Musculamine,精胺,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine	Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Spermine (Neuridine) 作为一个直接的自由基清除剂，具有抗病毒作用，能够保护 DNA 免受自由基的攻击。
T2952	Camphor 樟脑,(±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa	Influenza Virus; TRP/TRPV Channel	Membrane transporter/Ion channel; Microbiology/Virology
	Camphor (2-Camphanone) 是一种双环单萜酮，广泛存在于植物中，尤其是樟脑。它是一种激动剂，局部用作皮肤止痒剂和抗感染剂，具有抗病毒，镇咳和抗癌活性。
T5S0055	Chelidonine Helidonine,Khelidonin,白屈菜碱,Stylophorin	Apoptosis; Others; Influenza Virus	Apoptosis; Microbiology/Virology; Others
	Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱，有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。
T2754	Oxymatrine Oxysophoridine,氧化苦参碱,Matrine N-oxide	Influenza Virus; Autophagy; TGF-beta/Smad	Autophagy; Microbiology/Virology; Stem Cells
	Oxymatrine (Oxysophoridine) 是来自槐属物种根部的一种生物碱，具有抗炎，抗纤维化和抗肿瘤的作用。它是一种用于治疗乙型肝炎病毒的中药。它可抑制博卡病毒 MVC 复制，降低病毒基因表达并减少病毒感染诱导的细胞凋亡。它还可以抑制 iNOS 的表达和 TGF-β/Smad 通路。
T6343	Geldanamycin 格尔德霉素,NSC 122750	HSP; Influenza Virus; Tyrosine Kinases; Antibacterial; Antibiotic	Cytoskeletal Signaling; Metabolism; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Geldanamycin 是一种 HSP90 抑制剂（Kd：1.2 μM），可特异性破坏糖皮质激素受体 (GR)/HSP 的结合。
T5S0092	Epigoitrin BA-51-090278,Goitrine,D-Goitrin,表告依春,Goitrin	Antiviral; Influenza Virus	Immunology/Inflammation; Microbiology/Virology
	Epigoitrin (Goitrin) 是板蓝根中的一种天然生物碱，可通过线粒体抗病毒信号降低对流感病毒的易感性，具有抗病毒活性。
T2746	Sophocarpine monohydrate 槐果碱,Sophocarpine,槐果碱水合物	Apoptosis; Influenza Virus; Akt; PI3K; AMPK; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Sophocarpine monohydrate 是从传统草药苦参中提取的一种重要生物碱，具有抗肿瘤活性，可用于肝细胞癌，前列腺癌和结肠直肠癌。苦参具有抗病毒，抗肿瘤和抗炎等多种药理作用。
T7004	Tubercidin 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine	Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Tubercidin (Sparsomycin A) 是从Streptomyces tubercidicus 得到的抗生素，抑制粪链球菌生长的IC50值为 0.02 μM。它是腺苷磷酸化酶的弱抑制剂，并干扰腺苷和 AMP 的磷酸化。它有抗病毒作用。
T4136	Lapachol Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin	Others; Influenza Virus; Antibacterial; Parasite; Antifungal	Microbiology/Virology; Others
	Lapachol (CI75490) 是从Tabebuia avellanedae 中分离得到的一种萘醌。它具有具有抗菌、抗炎、镇痛、抗肿瘤和抗生素特性。
T3823	D-Pinitol Pinitol,Inzitol,D-(+)-Pinitol,D-松醇,Methylinositol,3-O-Methyl-D-chiro-inositol	Others; Influenza Virus	Microbiology/Virology; Others
	D-Pinitol (Methylinositol) 是一种存在于几种植物中，如松科和豆科植物的天然产物，具有抗病毒、杀幼虫、降血糖活性和心血管系统保护作用。
T0822	Catechin Catechinic acid,D-Catechin,(+)-Catechin,Cianidanol,儿茶素,Catechuic acid	Apoptosis; Influenza Virus; COX; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Catechin (Cianidanol) 是一种黄烷-3-醇，是一种天然酚类和抗氧化剂。它抑制环加氧酶-1，IC50为 1.4 μM。
T0725	Isoliquiritigenin 异甘草素,ISL,Isoliquiritigen,GU17	Apoptosis; Influenza Virus; Reductase; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; Metabolism; Microbiology/Virology
	Isoliquiritigenin (ISL) 是从光果甘草根中分离得到的一种黄酮类天然产物，具有抗肿瘤的活性。它抑制流感病毒复制，EC50为 24.7 μM，还能抑制 aldose reductase 的活性，IC50值为 320 nM。
T26288	Clovamide trans-Clovamide,N-trans-Caffeoy-L-dopa	Apoptosis; Influenza Virus; ROS; Antibacterial	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物，具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
T3919	Ginsenoside Rb2 Ginsenoside C,人参皂苷 Rb2,人参皂苷Rb2	GPR; Others; Influenza Virus; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Metabolism; Microbiology/Virology; Others
	Ginsenoside Rb2 (Ginsenoside C) 是人参提取物中的一种主要生物活性成分，具有抗病毒活性，可上调 GPR120 基因表达。
T1638	N-Acetylneuraminic acid 唾液酸,Acide aceneuramique,N-乙酰神经氨酸,NeuAc,Lactaminic acid	Others; Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	N-Acetylneuraminic acid (Acide aceneuramique) 是一种九碳唾液酸单糖，通常存在于细胞膜上的糖蛋白和哺乳动物细胞中的神经节苷脂等糖脂中。它可用于神经传递、白细胞外渗、病毒或细菌感染以及碳水化合物-蛋白质识别。
T2889	Isoferulic acid Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸	Influenza Virus; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物，有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体，增强 β-内啡肽的分泌并增加体外葡萄糖的使用。
T1335	Mycophenolic acid 霉酚酸,Mycophenolate,RS-61443	Apoptosis; Dehydrogenase; Endogenous Metabolite; Antibacterial; Antibiotic; UGT; Antifungal	Apoptosis; Metabolism; Microbiology/Virology
	Mycophenolic acid (Mycophenolate) 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂，EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂，具有抗血管生成和抗肿瘤作用。
T2951	β-Cyclodextrin Betadex,Beta-Cyclodextrin,β-环糊精,beta-环糊精,Cyclomaltoheptaose,NSC 269471	Others; Influenza Virus	Microbiology/Virology; Others
	β-Cyclodextrin (NSC 269471) 是一种环状多糖，由 α-D-吡喃型葡萄糖单元通过 α-(1,4) 糖苷键连接而成，通常用于增强药物的溶解度，可抑制流感病毒H1N1。
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天然产物

Cat.No: T2945

Target: P450, Antiviral, Influenza Virus

Cat.No: T0775

Target: Factor Xa, Influenza Virus

Cat.No: T5S1708

Target: Others, Influenza Virus

Cat.No: T3905

Synonym: 芒果

Target: Free radical scavengers, Antiviral, Influenza Virus

Eleutheroside B1

Cat.No: TN2331

Synonym: 刺五加苷B1

Target: Influenza Virus

Cat.No: T7602

Target: Influenza Virus, Endogenous Metabolite

Cat.No: T2957

Synonym: 牛蒡苷元,牛蒡子苷元,(-)-Arctigenin

Target: Apoptosis, MMP, Influenza Virus, Autophagy

Dehydroandrographolide succinate

Cat.No: T2S0257

Target: Others, Influenza Virus

Dehydroandrographolide

Cat.No: T2738

Target: NOS, Influenza Virus

Cat.No: TN1103

Synonym: 山荷叶素,二叶草素

Target: ATPase, Proton pump, Influenza Virus, HIV Protease

Tetrahydroepiberberine

Cat.No: T8187

Target: Others, Influenza Virus, Antifungal

Cat.No: T8286

Synonym: 三尖杉酯碱,三尖杉脂碱

Target: Others, Influenza Virus

Cat.No: T2854

Synonym: Forsythin,连翘苷

Target: P450, Influenza Virus, AMPK

Chebulagic acid

Cat.No: TQ0180

Target: SARS-CoV, Influenza Virus, Lipoxygenase, COX

Cephaeline hydrochloride

Cat.No: T3S1852

Target: Others, Virus Protease, Influenza Virus

Cat.No: T6S0232

Synonym: 圣草酚,Huazhongilexone

Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite

Cat.No: T4S1335

Synonym: Dephnoretin,西瑞香素,Thymelol

Target: Influenza Virus, Caspase, PKC

Cat.No: T2212

Synonym: 栀子苷,京尼平甙

Target: Beta Amyloid, Influenza Virus

Cat.No: T6677

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

Cat.No: T10835

Synonym: Desethylhydroxychloroquine

Target: Parasite, Antifection

Cat.No: T2858

Synonym: 5,6,7-Trihydroxyflavone,黄芩素,黄芩黄素

Target: Ferroptosis, Influenza Virus, ROS, Xanthine Oxidase

Cat.No: T13229

Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal

Cat.No: T2942

Synonym: Ficusin,Furocoumarin,补骨脂素,psoralene

Target: Apoptosis, Influenza Virus, HIV Protease, DNA/RNA Synthesis

Cat.No: T0681

Synonym: Rifamycin AMP,利福平,Rimactane,Rifampin

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic, Antifection

Cat.No: TN1480

Synonym: 吐根鹼,吐根酚碱

Target: Virus Protease, Influenza Virus, HIF

Cat.No: T3366

Synonym: ZINC19795976,三尖杉碱,(-)-Cephalotaxine,Cephalotaxlen

Target: Antiviral, Influenza Virus

Cat.No: T3342

Target: Apoptosis, Others, Influenza Virus, COX, Acyltransferase, HSV

Cat.No: T3341

Synonym: Elemicine,3,4,5-trimethoxyallylbenzene,榄香素

Target: Influenza Virus, 5-HT Receptor, Stearoyl-CoA Desaturase (SCD)

Dihydromyricetin

Cat.No: T2998

Synonym: Ampelopsin,Ampeloptin,二氢杨梅素

Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy

Dryocrassin ABBA

Cat.No: T4S1114

Synonym: 东北贯众素,Dryocrassin

Target: Influenza Virus, Antibacterial

Cat.No: T2844

Synonym: Quercetin 3-galactoside,金丝桃甙,金丝桃苷,Hyperin

Target: Others, Influenza Virus, Antifungal

Andrographolide

Cat.No: T2898

Synonym: Andrographis,穿心莲内酯

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

Cat.No: T3007

Synonym: Gerontine,Musculamine,精胺,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine

Target: Influenza Virus, Endogenous Metabolite

Cat.No: T2952

Synonym: 樟脑,(±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa

Target: Influenza Virus, TRP/TRPV Channel

Cat.No: T5S0055

Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Cat.No: T2754

Synonym: Oxysophoridine,氧化苦参碱,Matrine N-oxide

Target: Influenza Virus, Autophagy, TGF-beta/Smad

Cat.No: T6343

Synonym: 格尔德霉素,NSC 122750

Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic

Cat.No: T5S0092

Synonym: BA-51-090278,Goitrine,D-Goitrin,表告依春,Goitrin

Target: Antiviral, Influenza Virus

Sophocarpine monohydrate

Cat.No: T2746

Synonym: 槐果碱,Sophocarpine,槐果碱水合物

Target: Apoptosis, Influenza Virus, Akt, PI3K, AMPK, Autophagy

Cat.No: T7004

Synonym: 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T4136

Synonym: Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin

Target: Others, Influenza Virus, Antibacterial, Parasite, Antifungal

Cat.No: T3823

Synonym: Pinitol,Inzitol,D-(+)-Pinitol,D-松醇,Methylinositol,3-O-Methyl-D-chiro-inositol

Target: Others, Influenza Virus

Cat.No: T0822

Synonym: Catechinic acid,D-Catechin,(+)-Catechin,Cianidanol,儿茶素,Catechuic acid

Target: Apoptosis, Influenza Virus, COX, Endogenous Metabolite

Isoliquiritigenin

Cat.No: T0725

Synonym: 异甘草素,ISL,Isoliquiritigen,GU17

Target: Apoptosis, Influenza Virus, Reductase, Autophagy

Cat.No: T26288

Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa

Target: Apoptosis, Influenza Virus, ROS, Antibacterial

Ginsenoside Rb2

Cat.No: T3919

Synonym: Ginsenoside C,人参皂苷 Rb2,人参皂苷Rb2

Target: GPR, Others, Influenza Virus, Endogenous Metabolite

N-Acetylneuraminic acid

Cat.No: T1638

Synonym: 唾液酸,Acide aceneuramique,N-乙酰神经氨酸,NeuAc,Lactaminic acid

Target: Others, Influenza Virus, Endogenous Metabolite

Isoferulic acid

Cat.No: T2889

Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸

Target: Influenza Virus, Adrenergic Receptor

Mycophenolic acid

Cat.No: T1335

Synonym: 霉酚酸,Mycophenolate,RS-61443

Target: Apoptosis, Dehydrogenase, Endogenous Metabolite, Antibacterial, Antibiotic, UGT, Antifungal

β-Cyclodextrin

Cat.No: T2951

Synonym: Betadex,Beta-Cyclodextrin,β-环糊精,beta-环糊精,Cyclomaltoheptaose,NSC 269471

Target: Others, Influenza Virus

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