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Search Results for " chemopreventive "

13

抑制剂 & 化合物

48

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T40253	3-Phenylpropyl isothiocyanate	Others	Others
	3-Phenylpropyl isothiocyanate exhibits a potent inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis, thereby displaying strong chemopreventive properties [1] [2].
T0314	Hexylresorcinol 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol	Apoptosis; Tyrosinase; Antibacterial; Parasite	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物，具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂，有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。
T1872	Fenretinide 4-HPR,MK-4016,芬维A胺,4-hydroxy(phenyl)retinamide	Retinoid Receptor; Autophagy	Autophagy; Metabolism
	Fenretinide (4-HPR) 是一种可口服的合成类维生素 A 衍生物，具有潜在的抗肿瘤和化学预防活性。
T13602	CDDO-2P-Im CDDO-2-P-Im	Others	Others
	CDDO-2P-Im 在小鼠肺癌模型中显示出化学预防作用并降低了肺肿瘤的大小和严重程度。
T6743	(E/Z)-4-Hydroxytamoxifen 4-羟基他莫昔芬,(E/Z)-4-羟基他莫昔芬,Afimoxifene,4-Hydroxytamoxifen	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	(E/Z)-4-Hydroxytamoxifen (Afimoxifene) 是 tamoxifen 的活性代谢物和选择性雌激素受体（ER）调节剂，广泛用于乳腺癌的治疗和化学预防治疗。
T13603	CDDO-3P-Im	Necroptosis	Apoptosis
	CDDO-3P-Im 是一种具有口服活性的坏死性凋亡抑制剂，具有化学预防作用。 CDDO-3P-Im 可用于有关缺血/再灌注的研究。
T6157	Devimistat CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis; Dehydrogenase; Mitochondrial Metabolism	Apoptosis; Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) 是一种线粒体代谢抑制剂，还是一种lipoic acid 拮抗剂，能阻断线粒体能量代谢，诱导多种癌细胞凋亡。
T0153	Oltipraz 吡噻硫酮,NSC 347901,RP 35972	HIF/HIF Prolyl-Hydroxylase; HIV Protease; Reverse Transcriptase; Nrf2; HIF	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Oltipraz (RP 35972) 是一种 Nrf2的强效激活剂。它时间依赖性地抑制 HIF-1α激活，IC50为 10 μM，浓度 ≥ 10 μM 时完全消除 HIF-1α诱导。
T30228	Avicenol A
	Avicenol A is a cancer chemopreventive agent.
T34745	Sulforemate
	Sulforemate is a phase II enzyme inducer for chemopreventive activities.
T23661	Agamanone
	Agamanone is an anticancer agent. It also has antioxidant and chemopreventive properties.
T78587	Se-Methylselenocysteine hydrochloride Methylselenocysteine hydrochloride,Se-Methylseleno-L-cysteine hydrochloride	Beta-Secretase	Neuroscience
	Se-Methylselenocysteine hydrochloride 是一种甲基硒的前体，展现出显著的癌症化学预防和抗氧化活性。该化合物拥有优良的口服生物活性，并能有效诱导细胞凋亡(apoptosis)。
T40560	Benzyl selenocyanate
	Benzyl selenocyanate is a chemopreventive agent that effectively inhibits chemically induced tumors at both initiation and postinitiation stages in animal models. It acts as a potent inhibitor of DNA (cytosine-5)-methyltransferase (Mtase), with an IC50 of 8.4 μM.

化合物

3-Phenylpropyl isothiocyanate

Cat.No: T40253

Target: Others

Hexylresorcinol

Cat.No: T0314

Synonym: 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol

Target: Apoptosis, Tyrosinase, Antibacterial, Parasite

Cat.No: T1872

Synonym: 4-HPR,MK-4016,芬维A胺,4-hydroxy(phenyl)retinamide

Target: Retinoid Receptor, Autophagy

Cat.No: T13602

Synonym: CDDO-2-P-Im

Target: Others

(E/Z)-4-Hydroxytamoxifen

Cat.No: T6743

Synonym: 4-羟基他莫昔芬,(E/Z)-4-羟基他莫昔芬,Afimoxifene,4-Hydroxytamoxifen

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T13603

Target: Necroptosis

Cat.No: T6157

Synonym: CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism

Cat.No: T0153

Synonym: 吡噻硫酮,NSC 347901,RP 35972

Target: HIF/HIF Prolyl-Hydroxylase, HIV Protease, Reverse Transcriptase, Nrf2, HIF

Cat.No: T30228

Cat.No: T34745

Cat.No: T23661

Se-Methylselenocysteine hydrochloride

Cat.No: T78587

Synonym: Methylselenocysteine hydrochloride,Se-Methylseleno-L-cysteine hydrochloride

Target: Beta-Secretase

Benzyl selenocyanate

Cat.No: T40560

Cat. No.	Product Name	Target	Signaling Pathways
TN1046	Murrayone	Others	Others
	Murrayone 是一种提取自M. paniculata 中的含有香豆素的化合物。Murrayone 具有独特的药理特性，可用作防止癌症转移的化学预防剂。
TN1025	3,29-O-Dibenzoyloxykarounidiol	Others	Others
	3,29-O-Dibenzoyloxykarounidiol 是一种苯甲酸三萜烯酯，从 Momordica grosvenori 果实中提取。它能够抑制肿瘤启动子 TPA 诱导的 EB 病毒早期抗原活化。
T6670	Silymarin Silybin B,水飞蓟素	SARS-CoV	Microbiology/Virology
	Silymarin (Silybin B) 是一种多酚类黄酮，是从水飞蓟或水飞蓟的种子中提取的一种 SARS-CoV-2 主蛋白酶抑制剂。它可降低肿瘤细胞的增殖，血管生成以及胰岛素抵抗，用于预防和治疗肝脏疾病，有潜力研究 COVID-19 。
TN6742	β-Damascone Damascone,大马酮	Others	Others
	β-Damascone 是具有香气活性的大米挥发物，普遍用于香水成分中。它具有用作癌症化学预防剂及蚊香类杀虫剂的潜力。
T5372	L-SelenoMethionine L-(+)-Selenomethionine,L-硒代蛋氨酸	Apoptosis; Amino Acids and Derivatives; Endogenous Metabolite	Apoptosis; Metabolism
	L-SelenoMethionine (L-(+)-Selenomethionine) 是 Selenomethionine 的 L-异构体，是硒的主要天然食物形式。它是一种癌症化学预防剂，可以增加谷胱甘肽过氧化物酶的表达，还可以通过饮食补充降低癌症的发生率并诱导癌细胞凋亡。
T7727	Se-Methylselenocysteine Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC	BCL; IAP; Caspase	Apoptosis; Proteases/Proteasome
	Se-Methylselenocysteine (Se-MSC) 是具有口服活性的甲基硒前体，具有强大的抗氧化活性和抗癌活性。Se-Methylselenocysteine 可诱导细胞凋亡。
TQ0212	Glucoraphanin	Antioxidant; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Glucoraphanin 是一种硫代葡萄糖苷，存在于十字花科蔬菜中，是 Nrf2 诱导剂 sulforaphane 的前体，sulforaphane 有抗氧化、抗炎、抗癌作用。
T3411	Curdione 莪术二酮,(+)-Curdione	P450	Metabolism
	Curdione ((+)-Curdione) 是一种具有高生物活性的倍半萜类物质，从莪术中分离获得，具有抑制血小板聚集、抵抗血栓形成的作用。
T1059	Retinyl palmitate Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate,维生素A棕榈酸酯	Others; Endogenous Metabolite	Metabolism; Others
	Retinyl palmitate (Vitamin A palmitate) 是酯化的视黄醇，是表皮中维生素 A 的主要形式，在药品和化妆品中有广泛应用。
T4S0590	Columbin	Phospholipase; COX; Parasite	Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Columbin 是有口服活性的二萜呋喃内酯，选择性抑制COX-1和COX-2，EC50值为 327 μM 和 53.1 μM，具有抗炎和抗锥虫体作用。
T3399	Psoralidin	Others; Estrogen/progestogen Receptor; Reactive Oxygen Species; Lipoxygenase; Gamma-secretase; Akt; COX; Antibacterial	Cytoskeletal Signaling; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Psoralidin 是COX-2和5-LOX 的抑制剂，有抗癌，抗菌和抗炎作用。它显著下调NOTCH1信号传导，还极大地诱导活化氧产生。
TN1244	3'-Demethylnobiletin	LDL; NF-κB; Integrin; Lipoxygenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Metabolism; NF-κB
	3'-Demethylnobiletin 是样一种存在于柑橘类水果中的多甲氧基黄酮类化合物，是一种 Nobiletin 的衍生物。N 其中 obiletin 能够调节 Src，FAK 和 STAT3 信号传导来抗肿瘤，并能够抑制肿瘤血管生成。
T3909	Pulsatilla saponin D 白头翁皂苷D,Hederacolchiside A,SB365	Apoptosis; Others	Apoptosis; Others
	Pulsatilla saponin D (Hederacolchiside A) 是从朝鲜白头翁根部分离得到的一种天然产物，具有抗癌活性。
T1558	Resveratrol 白藜芦醇,trans-Resveratrol,SRT 501	Apoptosis; Mitophagy; IκB/IKK; Lipoxygenase; Sirtuin; COX; NADPH; DNA/RNA Synthesis; Nrf2; Antibacterial; Antibiotic; Autophagy; Antifungal	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	Resveratrol (SRT 501) 属于多酚类天然产物，是一种植物抗毒素，具有抗氧化和化学预防活性。Resveratrol 的靶点广泛，包括 COX、SIRT、LOC 等。Resveratrol 可以诱导细胞自噬和凋亡。
T1633	β-Carotene beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素	Apoptosis; ROS; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism
	β-Carotene (Provitamin A) 是一种天然存在的视黄醇（维生素 A）前体。它是一种 ROS 调节剂，具有抗氧化和抗炎活性。它可作为抗氧化剂或者促氧化剂，可诱导乳腺癌细胞凋亡，具有抗癌活性。
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮	Others	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone 是来自蜜柑皮中的黄酮，具有抗肿瘤起始活性和抗神经炎症作用。它能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子表达，降低 C6 细胞磷酸二酯酶活性。它能抑制胶原酶的活性，增加人真皮成纤维细胞新生细胞中 I 型前胶原含量。
T3342	Xanthohumol	Apoptosis; Others; Influenza Virus; COX; Acyltransferase; HSV	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; Others
	Xanthohumol 是从啤酒花中分离到的黄酮类化合物，可抑制 COX-1 和 COX-2 活性，具有抗肿瘤，抗血管生成的作用，还具有抗多种病毒的活性。
T1082	Benzyl isothiocyanate Benzoylthiocarbimide,苄基异硫氰酸酯,异硫氰酸苯甲酯,Isothiocyanic Acid Benzoyl Ester	Apoptosis; Antibacterial; Antibiotic	Apoptosis; Microbiology/Virology
	Benzyl isothiocyanate (Benzoylthiocarbimide) 是一种具有杀菌活性的天然异硫氰酸酯，最初存在于十字花科蔬菜中。它显示出免疫调节、抗寄生虫、抗生素、抗氧化、抗动脉粥样硬化、抗血管生成、抗转移、抗癌化疗和化学预防活性。
TN2330	Phenethyl ferulate Caffeic Acid 3-Methyl Phenethyl Ester,阿魏酸苯乙酯,阿魏酸苯乙醇酯	Lipoxygenase; COX	Immunology/Inflammation; Metabolism; Neuroscience
	Phenethyl ferulate (Caffeic Acid 3-Methyl Phenethyl Ester) 对化学诱导的结肠癌具有化学预防特性，可增强偶氮甲烷诱导的结肠肿瘤的细胞凋亡。它抑制环氧合酶(COX) 和 5-脂氧合酶 (5-LOX) ，IC50 值分别为 4.35 和 5.75 μM。
T5429	Theaflavin 3,3'-digallate 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG	Virus Protease; Antioxidant; HIV Protease; HSV	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂，IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制，可抑制 gp41 和 NS2B-3 蛋白酶的活性，并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚，有抗肿瘤作用。
T3403	Glabridin 光甘草定,Q-100692,KB-289522,LS-176045	Reactive Oxygen Species; Tyrosinase; GABA Receptor; Antibacterial; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
	Glabridin (KB-289522) 能够结合并激活PPARγ，EC50值为 6115 nM，是一种从Glycyrrhiza glabra 中分到的异黄烷类天然产物。它具有抗炎、抗菌、抗肾炎、抗氧化、抗肿瘤、抗糖尿病、抗骨质疏松、保护神经、保护心血管、清除自由基等作用。
T3S0013	Ethyl trans-caffeate 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester	Others	Others
	Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) 具有抗炎作用。它是一种有前途的天然化合物，未来在慢性肝病中的应用。它是一种有效的化学预防化合物，可防止因太阳紫外线照射引起的皮肤癌变。它是与人胰腺α-淀粉酶复合的代表性抑制剂的高分辨率结构。它强烈抑制 JB6 Cl41细胞的肿瘤转化，无毒性。 PI3K、ERK1/2 和 p38 激酶活性在体外通过与 HOEC 直接结合而受到抑制。
TMA0033	5'-Demethylaquillochin	NADPH-oxidase	Immunology/Inflammation
	5'-Demethylaquillochin and its isomer from the dichloromethane extract of E. cavaleriei have potential as chemopreventive agents through induction of detoxification enzymes. 5'-Demethylaquillochin exhibits the most potential chemopreventive ability.
TN3446	Aristolactam FI	Others	Others
	Aristolactam FI shows platelet aggregation inhibitory activity.It is a potential cancer chemotherapeutic and chemopreventive agent.
TN2807	21-Episerratenediol	Others	Others
	21-Episerratenediol may be as a potent cancer chemopreventive agent.
TN5329	Epitulipinolide diepoxide
	Epitulipinolide diepoxide has antioxidative and chemopreventive activities in skin melanoma cells, can significantly inhibit the proliferation of melanoma cells, it possesses cytotoxic activity against KB cells.
TN4496	Marginatoxin	Caspase; Fas/FasL	Apoptosis; Proteases/Proteasome
	Marginatoxin may be a promising chemopreventive agent for treating hepatocellular carcinoma, it induces human hepatoma BEL-7402 cells apoptosis in vitro and in vivo via activation of Fas/FasL-mediated apoptotic pathway.
TN3852	Dihydrolicoisoflavone	Antifection	Microbiology/Virology
	Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals.
TN1302	6,8-Diprenylorobol 6,8-二异戊烯基香豌豆苷元	Others; HIV Protease; Antifection	Microbiology/Virology; Others; Proteases/Proteasome
	6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals.
TN5022	Silyamandin	Others	Others
	Silyamandin may have antihepatotoxic and chemopreventive activities.
TN6651	Picrasidine Q
	Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.
TN1538	Curzerenone 莪术呋喃烯酮,莪术酮	Caspase; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52).
TN3366	Ailanthoidol	IL Receptor; NOS; COX; Prostaglandin Receptor; PPAR	DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potential as a chemopreventive agent against tumor promotion. Ailanthoidol has anti-adipogenic activit
TN2928	Pygenic acid A 3-Epicorosolic acid,脓毒酸A
	3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.3-Epicorosolic acid shows both potent α-glucosidase and pro
TN6591	Cannabisin B
	Cannabisin B possesses considerable antiproliferative activity and that it may be utilised as a promising chemopreventive agent against hepatoblastoma disease. It induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arre
TN2047	Pendulone	Antifection	Microbiology/Virology
	Pendulone could be a valuable chemopreventive agent, it shows strong inhibition on the effect of the cell cycle induced by TPA and shows potent anti-tumor-promoting activity for an in vivo two-stage carcinogenesis test.
TN1832	Kanzonol C	Others; NF-κB; Tyrosinase	NF-κB; Others; Proteases/Proteasome
	Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it shows the inhibition of matrix metalloproteinase (MMP)-2 secretion from brain tumor-derived glioblastoma cells.
TN4273	Isocoronarin D	Others	Others
	Isocoronarin D is a main active ingredient for inducing death of the tested cancer cells, it possesses a wide anti-cancer capability. Isocoronarin D may have potential chemopreventive activity, it can activate antioxidant response element (ARE) (EC50 57.6 ± 2.4 uM). It also shows the highest Hb F induction effect of 1.6-fold at 20 microM.
T82301	Gluconapin potassium
	Gluconapin potassium为萝卜硫素前体，后者为一抗癌效能显著的异硫氰酸酯。
TN3655	Cimiside E	ERK; TNF; ROS; Akt; PI3K; PKC; PPAR	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agen
TN4420	Latifolin 檀木	IL Receptor; IκB/IKK; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Antifection; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-ÎºB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays potent anticarcinogenic phase II marker enzyme, quinone reductase (QR) inducing activity and high chemopreventive indices. Latifolin also shows antifungal activity against white- and brown-rot fungi.
TN3070	4beta-Hydroxywithanolide E	PARP; HSP; NF-κB; COX	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by mo
TN3806	Dehydroglyasperin C	ERK; IκB/IKK; p38 MAPK; TNF; NF-κB; Akt; COX; PI3K; NADPH; DNA/RNA Synthesis; Nrf2; JNK; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
	Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases
T80996	Theasaponin E1
	Theasaponin E1，一种可从茶籽分离的茶皂苷，对人肿瘤细胞系K562和HL60展示了抗肿瘤潜能。此外，Theasaponin E1具备醌还原酶(QR)诱导活性，有助于作为抗癌预防药物的研究。
TN3348	(+)-Acuminatin Acuminatin	PAFR	GPCR/G Protein
	(+)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity against platelet aggregation with IC50 values of 108.5 and 90.02 uM, respectively. (+)-Acuminatin, and machilin G show dose-dependent potent inhibitory activities against PLCgamma1 in vitro with IC50 values ranging from 8.8 to 26.0 microM, the inhibition of PLCgamma1 may be an important mechanism for an antiproliferative effect on the huma...
TN4291	Isofuranodiene	IL Receptor; NOS	Immunology/Inflammation
	Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apo
TN4471	Lysicamine	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the mini
TN1783	Isolicoflavonol 异甘草黄酮醇	Lipid	Metabolism
	Isolicoflavonol 以可逆和混合的方式抑制人羧酸酯酶2介导的荧光素二乙酸酯水解， Ki 小于1.0 μM。

天然产物

Cat.No: TN1046

Target: Others

3,29-O-Dibenzoyloxykarounidiol

Cat.No: TN1025

Target: Others

Cat.No: T6670

Synonym: Silybin B,水飞蓟素

Target: SARS-CoV

Cat.No: TN6742

Synonym: Damascone,大马酮

Target: Others

L-SelenoMethionine

Cat.No: T5372

Synonym: L-(+)-Selenomethionine,L-硒代蛋氨酸

Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite

Se-Methylselenocysteine

Cat.No: T7727

Synonym: Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC

Target: BCL, IAP, Caspase

Cat.No: TQ0212

Target: Antioxidant, Reactive Oxygen Species

Cat.No: T3411

Synonym: 莪术二酮,(+)-Curdione

Target: P450

Retinyl palmitate

Cat.No: T1059

Synonym: Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate,维生素A棕榈酸酯

Target: Others, Endogenous Metabolite

Cat.No: T4S0590

Target: Phospholipase, COX, Parasite

Cat.No: T3399

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

3'-Demethylnobiletin

Cat.No: TN1244

Target: LDL, NF-κB, Integrin, Lipoxygenase, DNA/RNA Synthesis

Pulsatilla saponin D

Cat.No: T3909

Synonym: 白头翁皂苷D,Hederacolchiside A,SB365

Target: Apoptosis, Others

Cat.No: T1558

Synonym: 白藜芦醇,trans-Resveratrol,SRT 501

Target: Apoptosis, Mitophagy, IκB/IKK, Lipoxygenase, Sirtuin, COX, NADPH, DNA/RNA Synthesis, Nrf2, Antibacterial, Antibiotic, Autophagy, Antifungal

Cat.No: T1633

Synonym: beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素

Target: Apoptosis, ROS, Endogenous Metabolite

3,5,6,7,8,3',4'-Heptemthoxyflavone

Cat.No: TN1088

Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮

Target: Others

Cat.No: T3342

Target: Apoptosis, Others, Influenza Virus, COX, Acyltransferase, HSV

Benzyl isothiocyanate

Cat.No: T1082

Synonym: Benzoylthiocarbimide,苄基异硫氰酸酯,异硫氰酸苯甲酯,Isothiocyanic Acid Benzoyl Ester

Target: Apoptosis, Antibacterial, Antibiotic

Phenethyl ferulate

Cat.No: TN2330

Synonym: Caffeic Acid 3-Methyl Phenethyl Ester,阿魏酸苯乙酯,阿魏酸苯乙醇酯

Target: Lipoxygenase, COX

Theaflavin 3,3'-digallate

Cat.No: T5429

Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

Cat.No: T3403

Synonym: 光甘草定,Q-100692,KB-289522,LS-176045

Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR

Ethyl trans-caffeate

Cat.No: T3S0013

Synonym: 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester

Target: Others

5'-Demethylaquillochin

Cat.No: TMA0033

Target: NADPH-oxidase

Aristolactam FI

Cat.No: TN3446

Target: Others

21-Episerratenediol

Cat.No: TN2807

Target: Others

Epitulipinolide diepoxide

Cat.No: TN5329

Cat.No: TN4496

Target: Caspase, Fas/FasL

Dihydrolicoisoflavone

Cat.No: TN3852

Target: Antifection

6,8-Diprenylorobol

Cat.No: TN1302

Synonym: 6,8-二异戊烯基香豌豆苷元

Target: Others, HIV Protease, Antifection

Cat.No: TN5022

Target: Others

Cat.No: TN6651

Cat.No: TN1538

Synonym: 莪术呋喃烯酮,莪术酮

Target: Caspase, Antifection

Cat.No: TN3366

Target: IL Receptor, NOS, COX, Prostaglandin Receptor, PPAR

Cat.No: TN2928

Synonym: 3-Epicorosolic acid,脓毒酸A

Cat.No: TN6591

Cat.No: TN2047

Target: Antifection

Cat.No: TN1832

Target: Others, NF-κB, Tyrosinase

Cat.No: TN4273

Target: Others

Gluconapin potassium

Cat.No: T82301

Cat.No: TN3655

Target: ERK, TNF, ROS, Akt, PI3K, PKC, PPAR

Cat.No: TN4420

Synonym: 檀木

Target: IL Receptor, IκB/IKK, TNF, NOS, NF-κB, COX, Nrf2, Prostaglandin Receptor, Antifection, Autophagy

4beta-Hydroxywithanolide E

Cat.No: TN3070

Target: PARP, HSP, NF-κB, COX

Dehydroglyasperin C

Cat.No: TN3806

Target: ERK, IκB/IKK, p38 MAPK, TNF, NF-κB, Akt, COX, PI3K, NADPH, DNA/RNA Synthesis, Nrf2, JNK, Autophagy

Cat.No: T80996

Cat.No: TN3348

Synonym: Acuminatin

Target: PAFR

Cat.No: TN4291

Target: IL Receptor, NOS

Cat.No: TN4471

Target: IL Receptor, Antifection

Isolicoflavonol

Cat.No: TN1783

Synonym: 异甘草黄酮醇

Target: Lipid

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