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Search Results for " ral "

245

抑制剂 & 化合物

85

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T24706	RBC10 RBC 10,RBC-10	GTPase	GPCR/G Protein
	RBC10 抑制 Ral 与其效应物 RALBP1 的结合，以及抑制 Ral 介导的鼠胚胎成纤维细胞的细胞扩散和人类癌细胞系的非贴壁依赖性生长。
T13140	Umbralisib R-enantiomer TGR-1202 R-enantiomer,RP5264 R-enantiomer	PI3K	PI3K/Akt/mTOR signaling
	Umbralisib R-enantiomer (RP5264 R-enantiomer) 是 PI3K 的δ型抑制剂，是 TGR-1202 活性较低的对映体。Umbralisib R-enantiomer 对δ型 pi3激酶的 IC50，至少比抑制剂对其他 PI3K 亚型(A， β和γ)的 IC50低20倍。
T77122	Praluzatamab	Others	Others
	Praluzatamab 是一种靶向活化白细胞粘附分子 (ALCAM/CD116) 的单克隆抗体。Praluzatamab 是 Praluzatamab ravtansine 的裸抗，可用于合成抗体活性分子偶联物（Praluzatamab ravtansine)。Praluzatamab 可用于研究研究乳腺癌。
T0660	Beta-Tetralone 2-Tetralone,beta-四氢萘酮	P450	Metabolism
	Beta-Tetralone (2-Tetralone) 是 tetralin 的酮衍生物。
T20549	Neutral red	Others	Others
	Neutral Red 是含氮 pH 指示剂(pKi=6.8)，是类囊体内部酸化的指示剂。它能够将溶酶体染成红色。
T9395	(1S,4R)-N-Desmethyl Sertraline Hydrochloride	Others	Others
	(1S,4R)-N-DesmethylSertralineHydrochloride 是一种Serotonin transporter 和 Norepinephrine transporter 抑制剂，IC5分别为19 nM 和35 nM.
T67904	Antiviral agent	HBV	Microbiology/Virology
	Antiviral agent是一种具有抗乙型肝炎活性的噻唑烷。
T36375	Ralaniten triacetate
	Ralaniten triacetate (EPI-506) is a novel pro-drug of Ralaniten, functioning as an orally active inhibitor of the androgen receptor (AR) N-terminal domain (NTD). Its remarkable first-in-class status signifies its unique nature within the field. This compound exhibits significant efficacy against various AR species, including AR-v7, which are associated with resistance. Notably, Ralaniten triacetate's activity encompasses full-length AR as well [1][2].
T77632	Antiviral agent 34	Antiviral; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation
	Antiviral agent 34 是一种可口服且作用效果较强的抗病毒化合物，抑制甲型和乙型流感病毒。Antiviral agent 34 通过调节 RNA 聚合酶来抑制流感病毒的增殖。Antiviral agent 34 可用于研究病毒感染。
T28918	Talviraline Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979	HIV Protease; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Talviraline (Bay 10-8979) 是一种 RNA 引导的 DNA 聚合酶抑制剂。Talviraline 对多种人类细胞系以及新鲜人类外周血淋巴细胞和巨噬细胞中的 HIV-1 诱导的细胞杀伤和 HIV-1 复制具有很强的抑制作用。
T14358	Avoralstat BCX4161	Others	Others
	Avoralstat (BCX4161) 是血浆激肽释放酶(PKK)抑制剂，具有口服活性，可用于遗传性血管性水肿的研究。
T7547	Ralfinamide mesylate FCE-26742A (mesylate)	Sodium Channel	Membrane transporter/Ion channel
	Ralfinamide mesylate (FCE-26742A (mesylate)) 是一种口服有效，来源于 α-aminoamide 的钠离子通道阻滞剂, 在缓解疼痛方面有研究价值。
T9449	Nitrofural [(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺	Antibacterial	Microbiology/Virology
	Nitrofural 是 20 世纪已在临床应用中确立的硝基呋喃。 Nitrofural 在临床上对广泛的革兰氏阳性和革兰氏阴性细菌（包括许多常见的泌尿道病原体菌株）仍然有效。
T6482	Efaproxiral Sodium 乙丙昔罗钠,RSR13 sodium	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Efaproxiral Sodium (RSR13 sodium) 是血红蛋白 (Hb) 合成变构调节剂，能够减少血红蛋白氧 (O2) 的结合亲和力。
T17111	Todralazine hydrochloride Ecarazine hydrochloride,盐酸托屈嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Todralazine hydrochloride (Ecarazine hydrochloride) 是一种 β2AR 阻滞剂，具有抗氧化和自由基清除活性。 Todralazine hydrochloride 可用于抗高血压的研究。
T7349	Ralfinamide (S)-2-[[4-[(2-氟苄基)氧基]苄基]氨基]丙酰胺,Priralfinamide,FCE-26742A	Sodium Channel	Membrane transporter/Ion channel
	Ralfinamide (Priralfinamide) 是一种具有口服活性的，来源于 α-aminoamide 的钠离子通道阻滞剂, 在缓解疼痛方面有研究的价值。
T19748	Butralin A-820,A820,A 820,丁烯酯甲酸,Tamex	Others	Others
	Butralin (A-820) 是一种除草剂和植物生长控制剂。
T28255	Opaviraline GW420867X,GW-867,HBY-1293,GW867,GW-420867X	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Opaviraline (GW-420867X) 是一种有效逆转录酶抑制剂，对Human immunodeficiency virus 1具有抑制作用，具有治疗HIV 感染的潜力。
T1613	Hydralazine hydrochloride Hydralazine HCl,Apresoline,盐酸肼屈嗪	MAO; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Neuroscience
	Hydralazine hydrochloride (Apresoline) 是一种直接作用的血管舒张剂，可抗高血压。
T19999	1-Tetralol, (S)- (S)-(+)-1,2,3,4-四氢-1-萘酚,(S)-Tetralin-1-ol,(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol,(S)-1-Hydroxytetralin,J330.337C	Others	Others
	1-Tetralol, (S)- ((S)-1-Hydroxytetralin) 可在细胞实验中用作 AKR1C1 的底物。
T26939	Cadralazine ISF 2469,卡屈嗪,ISF-2469,ISF2469	Others	Others
	Cadralazine (ISF 2469) 是一种外周小动脉血管扩张剂，可用于作为抗高血压药物的研究。
T20508	Orfralure
	Orfralure is a biochemical substance.
T5330	Fluralaner AH252723,氟雷拉纳,A1443	GABA Receptor; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Fluralaner (A1443) 是一种异恶唑啉杀外寄生虫剂。它有效且选择性地抑制 GABA 受体通道阻滞剂 EBOB 与家蝇头膜的结合，IC50值为 455 pM。
T1111	Pralidoxime Chloride 2-PAM chloride,吡啶醛肟甲氯,2-Pyridinealdoxime methochloride,2-PAM (chloride)	AChE	Neuroscience
	Pralidoxime Chloride (2-PAM chloride) 是一种肟类化合物，对中毒乙酰胆碱酯酶具有恢复作用，可用于有机磷中毒的研究。
TP1929L1	Saralasin acetate(34273-10-4 free base)	RAAS	Endocrinology/Hormones
	Saralasin acetate(34273-10-4 free base) 是一种非选择性血管紧张素 II 拮抗剂。
T2265	Bimiralisib 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2	Others; PI3K; S6 Kinase; mTOR	MAPK; Others; PI3K/Akt/mTOR signaling
	Bimiralisib (PI3K-IN-2) 是一种有效的，可渗透脑的 mTOR/PI3K 抑制剂，是一种 mTORC1和 mTORC2抑制剂。它能够抑制 PI3Kα,PI3Kδ,PI3Kβ,PI3Kγ和 mTOR，IC50分别为 33 nM，451 nM，661 nM，708 nM 和 89 nM。
T21355	6-Chloro-1-tetralone 6-Chloro-α-Tetralone,5-CHLORO-L-INDOMONE,6-chloro-3;5-CHLORO-1-INDOMONE,5-CHLORO-1-INDOMONE,6-chloro-3	Others	Others
	6-Chloro-1-tetralone (6-chloro-3;5-Chloro-1-Indomone) 是合成药物化合物的重要中间体。
T39350	Sebetralstat KVD900	Others	Others
	Sebetralstat (KVD900) 是一种血浆激肽释放酶抑制剂，可用于代谢性疾病的研究。
T14527	Benfluralin
	Benfluralin 是一种除草剂，是一种农用化学品，可用作芽前除草剂。用于控制一系列粮食和非粮食作物中的草和其他杂草。
T63272	Edralbrutinib TG-1701	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	Edralbrutinib (TG-1701) 是有效的BTK抑制剂，具有抗癌活性，可用于治疗肿瘤、免疫系统疾病、血液及淋巴系统疾病。Edralbrutinib可用于研究膜性肾小球肾炎和视神经脊髓炎。
T4635	Ralinepag APD811	Others; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Others
	Ralinepag (APD811) 是一种可口服的非前列腺素前列环素 (IP) 受体激动剂，对人和大鼠 IP 受体以及人 DP1 受体的 EC50 分别为 8.5、530 和 850 nM。
T16569	Praliciguat IW-1973	Others; Guanylate cyclase	GPCR/G Protein; Others
	Praliciguat (IW-1973) 是一种有效且具有口服活性的可溶性鸟苷酸环化酶 (sGC) 刺激剂，还增强 NO 信号传导，可作为血管扩张剂。在 HEK-293 细胞中，它能够刺激 sGC，EC50值为 197 nM。
T8900	Seralutinib GB002	PDGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Seralutinib (GB002) 是可吸入的PDGFRα 和 PDGFRβ激酶抑制剂，可用于研究肺动脉高压。
T3526	Dasotraline hydrochloride SEP-225289 hydrochloride,达索曲林盐酸盐	Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine	GPCR/G Protein; Neuroscience
	Dasotraline hydrochloride (SEP-225289 hydrochloride) 是具有阻断多巴胺 (IC50=4 nM)，去甲肾上腺素 (IC50=6 nM) 和三羟色胺转运蛋白 (IC50=11 nM)的三重再摄取抑制剂。
T22592	ATPγS tetralithium salt ATP-gamma-S tetralithium salt	PERK	Apoptosis
	ATPγS tetralithium salt 是真核生物翻译起始因子 eIF4A 的核苷酸水解和RNA解链活性的底物，与 p97 突变体和朊病毒相关。
T6632	Raltitrexed ZD1694,雷替曲塞,D1694,ICI-D1694,Tomudex	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Raltitrexed (D1694) 是一种抗代谢药物，通过抑制胸苷酸合成酶起作用，可用于化疗。
T6120	Pralatrexate Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙	Apoptosis; DHFR; Antifolate; TAM Receptor	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Tyrosine Kinase/Adaptors
	Pralatrexate (10-Propargyl-10-deazaaminopterin) 是一种抗叶酸剂，也是二氢叶酸还原酶抑制剂，Ki 值为 13.4 pM。它具有抗肿瘤活性，可研究复发/难治性 T 细胞淋巴瘤。它是叶酰聚谷氨酸合成酶的底物，具有改善的细胞摄取和保留能力。
T1251	Dicloralurea 双(三氯乙醛基)脲,Dichlorolurea,双 (三氯乙醛基) 脲,DCU	Others	Others
	Dicloralurea (DCU) 是一种兽用的食品添加剂，可用作生长刺激剂。
T28503	Ralitoline GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum
	Ralitoline (Ralitolinum) 是一种抗惊厥剂，具有抗癌活性和钠通道阻断活性。
T9183	Ralmitaront RO6889450	Others	Others
	Ralmitaront (RO6889450) 是口服具有活力的口服微量胺相关受体 1 (TAAR1) 的部分激动剂。它是一种神经抑制剂，可用于研究神经相关疾病，如精神分裂症 (SCZ)、分裂情感性障碍。
T10497	Benralizumab BIW-8405,MEDI-563	Apoptosis; IL Receptor; Interleukin	Apoptosis; Immunology/Inflammation
	Benralizumab (MEDI-563) 是一种靶向白介素 5 受体 α (IL-5Rα) 单克隆抗体，通过增强抗体依赖性细胞介导的细胞毒性促使嗜酸性粒细胞快速进行反应。Benralizumab 可用于严重的嗜酸性哮喘，可用于预防慢性阻塞性肺病加重。
T1338	Sucralfate 硫糖铝,Sucrose octasulfate–aluminum complex	FGFR; Others; Antibacterial; Prostaglandin Receptor	Angiogenesis; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Others; Tyrosine Kinase/Adaptors
	Sucralfate (Sucrose octasulfate–aluminum complex) 是一种口服活性胃保护剂。它抑制消化性活性，并与黏膜损伤时暴露的带负电荷的上皮下蛋白结合，形成一层粘性层，保护血管床和增殖区。它可用于预防和治疗胃肠道疾病。
T2365	Pilaralisib SAR245408,XL-147	PI3K	PI3K/Akt/mTOR signaling
	Pilaralisib (XL-147) 是一种有效的、选择性的 I 类PI3Ks 抑制剂，能够抑制 PI3Kα (IC50:39 nM)，PI3Kβ (IC50:383 nM)，PI3Kγ (IC50:23 nM) 和 PI3Kδ (IC50:36 nM)。
T3270	Dihydralazine sulfate 1,4-Dihydrazinophthalazine sulfate,硫酸双肼屈嗪,Hydralazine sulfate,Nepresol,Depressan,Dihydralazine sulphate	Others	Others
	Dihydralazine sulfate (Nepresol) 是一种抗高血压的药物。
T60440	Antiviral agent 17
	Antiviral agent 17 (Compound 4) 是一种抗感染剂，在人类复制子试验中显著保留其抗病毒作用，EC50值为0.015 μM。Antiviral agent 17 对小鼠诺如病毒(MNV)表现出良好的抗病毒活性。Antiviral agent 17 在研究传染性和恶性疾病方面具有潜力。
T2239L	Raltegravir 雷特格韦,MK-0518	HIV Protease; Integrase	Microbiology/Virology; Proteases/Proteasome
	Raltegravir (MK-0518) 是一种HIV 整合酶抑制剂。
T6047	Ralimetinib dimesylate LY2228820 dimesylate,Ralimetinib,LY2228820,Ralimetinib Mesylate	Apoptosis; p38 MAPK; Autophagy	Apoptosis; Autophagy; MAPK
	Ralimetinib dimesylate (LY2228820 dimesylate) 是一种选择性，ATP 竞争性的 p38 MAPK α/β抑制剂，IC50分别为5.3 和 3.2 nM。
T4976	Umbralisib TGR-1202,RP5264,TGR 1202,TGR1202	PI3K	PI3K/Akt/mTOR signaling
	Umbralisib (TGR 1202) 是一种PI3Kδ抑制剂，IC50=22.2 nM，EC50=24.3 nM。它同时可抑制CK1ε，EC50=6.0 μM。
T19982	Tralkoxydim 三甲苯草酮,Splendor,Tralkoxydime	Acetyl-CoA Carboxylase	Metabolism
	Tralkoxydim (Tralkoxydime) 是一种烷基酮类除草剂。 Tralkoxydim 用作 ACCase 抑制剂。
T77093	Theralizumab TGN1412,TAB-08,TABO8	Others	Others
	Theralizumab (TGN1412) 是一种抗靶向 CD28 的单克隆抗体，可直接刺激 T 细胞。Theralizumab 具有抗肿瘤活性，用于治疗 B 细胞慢性淋巴细胞白血病和类风湿性关节炎。

化合物

Cat.No: T24706

Synonym: RBC 10,RBC-10

Target: GTPase

Umbralisib R-enantiomer

Cat.No: T13140

Synonym: TGR-1202 R-enantiomer,RP5264 R-enantiomer

Target: PI3K

Cat.No: T77122

Target: Others

Cat.No: T0660

Synonym: 2-Tetralone,beta-四氢萘酮

Target: P450

Cat.No: T20549

Target: Others

(1S,4R)-N-Desmethyl Sertraline Hydrochloride

Cat.No: T9395

Target: Others

Antiviral agent

Cat.No: T67904

Target: HBV

Ralaniten triacetate

Cat.No: T36375

Antiviral agent 34

Cat.No: T77632

Target: Antiviral, DNA/RNA Synthesis

Cat.No: T28918

Synonym: Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979

Target: HIV Protease, DNA/RNA Synthesis

Cat.No: T14358

Synonym: BCX4161

Target: Others

Ralfinamide mesylate

Cat.No: T7547

Synonym: FCE-26742A (mesylate)

Target: Sodium Channel

Cat.No: T9449

Synonym: [(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺

Target: Antibacterial

Efaproxiral Sodium

Cat.No: T6482

Synonym: 乙丙昔罗钠,RSR13 sodium

Target: Reactive Oxygen Species

Todralazine hydrochloride

Cat.No: T17111

Synonym: Ecarazine hydrochloride,盐酸托屈嗪

Target: Adrenergic Receptor

Cat.No: T7349

Synonym: (S)-2-[[4-[(2-氟苄基)氧基]苄基]氨基]丙酰胺,Priralfinamide,FCE-26742A

Target: Sodium Channel

Cat.No: T19748

Synonym: A-820,A820,A 820,丁烯酯甲酸,Tamex

Target: Others

Cat.No: T28255

Synonym: GW420867X,GW-867,HBY-1293,GW867,GW-420867X

Target: HIV Protease

Hydralazine hydrochloride

Cat.No: T1613

Synonym: Hydralazine HCl,Apresoline,盐酸肼屈嗪

Target: MAO, HIF/HIF Prolyl-Hydroxylase

1-Tetralol, (S)-

Cat.No: T19999

Synonym: (S)-(+)-1,2,3,4-四氢-1-萘酚,(S)-Tetralin-1-ol,(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol,(S)-1-Hydroxytetralin,J330.337C

Target: Others

Cat.No: T26939

Synonym: ISF 2469,卡屈嗪,ISF-2469,ISF2469

Target: Others

Cat.No: T20508

Cat.No: T5330

Synonym: AH252723,氟雷拉纳,A1443

Target: GABA Receptor, Parasite

Pralidoxime Chloride

Cat.No: T1111

Synonym: 2-PAM chloride,吡啶醛肟甲氯,2-Pyridinealdoxime methochloride,2-PAM (chloride)

Target: AChE

Saralasin acetate(34273-10-4 free base)

Cat.No: TP1929L1

Target: RAAS

Cat.No: T2265

Synonym: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2

Target: Others, PI3K, S6 Kinase, mTOR

6-Chloro-1-tetralone

Cat.No: T21355

Synonym: 6-Chloro-α-Tetralone,5-CHLORO-L-INDOMONE,6-chloro-3;5-CHLORO-1-INDOMONE,5-CHLORO-1-INDOMONE,6-chloro-3

Target: Others

Cat.No: T39350

Synonym: KVD900

Target: Others

Cat.No: T14527

Cat.No: T63272

Synonym: TG-1701

Target: BTK

Cat.No: T4635

Synonym: APD811

Target: Others, Prostaglandin Receptor

Cat.No: T16569

Synonym: IW-1973

Target: Others, Guanylate cyclase

Cat.No: T8900

Synonym: GB002

Target: PDGFR

Dasotraline hydrochloride

Cat.No: T3526

Synonym: SEP-225289 hydrochloride,达索曲林盐酸盐

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine

ATPγS tetralithium salt

Cat.No: T22592

Synonym: ATP-gamma-S tetralithium salt

Target: PERK

Cat.No: T6632

Synonym: ZD1694,雷替曲塞,D1694,ICI-D1694,Tomudex

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T6120

Synonym: Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙

Target: Apoptosis, DHFR, Antifolate, TAM Receptor

Cat.No: T1251

Synonym: 双(三氯乙醛基)脲,Dichlorolurea,双 (三氯乙醛基) 脲,DCU

Target: Others

Cat.No: T28503

Synonym: GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum

Cat.No: T9183

Synonym: RO6889450

Target: Others

Cat.No: T10497

Synonym: BIW-8405,MEDI-563

Target: Apoptosis, IL Receptor, Interleukin

Cat.No: T1338

Synonym: 硫糖铝,Sucrose octasulfate–aluminum complex

Target: FGFR, Others, Antibacterial, Prostaglandin Receptor

Cat.No: T2365

Synonym: SAR245408,XL-147

Target: PI3K

Dihydralazine sulfate

Cat.No: T3270

Synonym: 1,4-Dihydrazinophthalazine sulfate,硫酸双肼屈嗪,Hydralazine sulfate,Nepresol,Depressan,Dihydralazine sulphate

Target: Others

Antiviral agent 17

Cat.No: T60440

Cat.No: T2239L

Synonym: 雷特格韦,MK-0518

Target: HIV Protease, Integrase

Ralimetinib dimesylate

Cat.No: T6047

Synonym: LY2228820 dimesylate,Ralimetinib,LY2228820,Ralimetinib Mesylate

Target: Apoptosis, p38 MAPK, Autophagy

Cat.No: T4976

Synonym: TGR-1202,RP5264,TGR 1202,TGR1202

Target: PI3K

Cat.No: T19982

Synonym: 三甲苯草酮,Splendor,Tralkoxydime

Target: Acetyl-CoA Carboxylase

Cat.No: T77093

Synonym: TGN1412,TAB-08,TABO8

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5625	Zearalenone 玉米,Mycotoxin F2,玉米烯酮,RAL,F2 toxin,Toxin F2	Others	Others
	Zearalenone (F2 toxin) 是真菌毒素，主要由食物和饲料中的 Fusarium 产生。它会引起幼龄母猪乳房发育早熟或其它雌激素效应。它在猪、牛、羊体内具有雌激素活性，急性毒性低。
TN1008	Psoralenoside	CaMK; Calcium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Psoralenoside 是源于补骨脂中的苯并呋喃苷，具有抗肿瘤、抗菌、促进成骨细胞增殖和雌激素样活性。它对组胺 H1、钙调素和电压门控 l 型钙通道具有较高的亲和力。
T13542	α-Zearalenol	Estrogen Receptor/ERR	Endocrinology/Hormones
	α-Zearalenol 是一种霉菌毒素，对雌激素受体具有高亲和力。它是 zearalenone (ZEN) 的一种衍生物，由于其异种雌激素效应可引起动物的生殖障碍。
T2943	5-Hydroxymethylfurfural 5-羟甲基糠醛,2-Hydroxymethyl-5-furfural,2-Formyl-5-hydroxymethylfuran,5-Hydroxymethyl-2-furaldehyde,5-(Hydroxymethyl)furan-2-carbaldehyde	Others; Antifungal	Microbiology/Virology; Others
	5-Hydroxymethylfurfural (2-Formyl-5-hydroxymethylfuran) 是来自木质纤维素生物质，能抑制酵母的生长和发酵。
T8213	Isolinderalactone	NOS; STAT	Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Isolinderalactone 具有抗炎和抗癌能力，具有中等的 iNOS 抑制活性，IC50 值为 0.30 uM。
T1399	Sucralose Trichlorosucrose,三氯蔗糖,E955	Others; Endogenous Metabolite	Metabolism; Others
	Sucralose (Trichlorosucrose) 是一种无营养的人工甜味剂 (sweetener) 和代糖，它能够激活保守神经的禁食响应，从而刺激啮齿动物产生食欲。
T5090	2-Methylbutyraldehyde 2-Ethylpropanal,RS)-2-Methylbutanal,2-甲基丁醛	Others	Others
	2-Methylbutyraldehyde (2-Ethylpropanal) 属于短链醛类化合物，白术饮片中的焦香味物质之一。
T7921	β-Cyclocitral beta-Cyclocitral,β-环柠檬醛	Others	Others
	β-Cyclocitral 是 β-胡萝卜素的挥发性氧化衍生物，是微囊藻特有的掠食性动物防御信号。它是一种强大的驱虫剂。它是主要的挥发性萜类化合物之一，可以上调防御基因的表达，从而增强过量光照 (EL) 的适应性。
T3S0289	Araloside X	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi
Fr12275	7-Methoxy-1-tetralone	Others	Others
	7-Methoxy-1-tetralone 可能具有杀虫活性。
T1549	Raloxifene hydrochloride LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl	Estrogen Receptor/ERR; Others; MAO; Estrogen/progestogen Receptor; Autophagy	Autophagy; Endocrinology/Hormones; Metabolism; Neuroscience; Others
	Raloxifene hydrochloride (LY156758 hydrochloride) 是一种选择性且可口服的雌激素受体调节剂，用于预防绝经后妇女的骨质疏松症。它对骨骼和胆固醇代谢具有雌激素激动作用，但对乳腺和子宫组织具有完全的雌激素拮抗作用。
T2942	Psoralen Ficusin,Furocoumarin,补骨脂素,psoralene	Apoptosis; Influenza Virus; HIV Protease; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Psoralen (Ficusin) 是从补骨脂种子中提取的一种香豆素。它具有如抗癌、抗氧化、抗抑郁、抗癌、抗菌、抗病毒等多种生物学特性。
T3399	Psoralidin	Others; Estrogen/progestogen Receptor; Reactive Oxygen Species; Lipoxygenase; Gamma-secretase; Akt; COX; Antibacterial	Cytoskeletal Signaling; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Psoralidin 是COX-2和5-LOX 的抑制剂，有抗癌，抗菌和抗炎作用。它显著下调NOTCH1信号传导，还极大地诱导活化氧产生。
T3418	Demethylzeylasteral 去甲泽拉木醛,Demethylzeylasteral (T-96)	Apoptosis; UGT	Apoptosis; Metabolism
	Demethylzeylasteral (Demethylzeylasteral (T-96)) 分离自雷公藤，具有抗炎、免疫抑制和抗肿瘤活性。它通过阻断 TGF-β 信号通路，抑制三阴性乳腺癌的侵袭，它能显著减轻动脉粥样硬化。
T5657	Veratraldehyde 3,4-Dimethoxybenzaldehyde,藜芦醛	Antifungal	Microbiology/Virology
	Veratraldehyde (3,4-Dimethoxybenzaldehyde) 是一种能够使用于香料，农业化学和制药工业中的重要化学品。
T5S1897	Linderalactone	Apoptosis; Others; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
	Linderalactone 是从乌药中分离出来的一种倍半萜烯内酯，通过调节凋亡相关蛋白的表达和抑制 JAK/STAT 信号通路来抑制癌细胞生长。它以 IC50值为 15 µM 来抑制肺癌 A-549 细胞的增殖。
T4S0290	Araloside A Chikusetsusaponin IV,竹节参皂苷IV	RAAS; Fas/FasL	Apoptosis; Endocrinology/Hormones
	Araloside A (Chikusetsusaponin IV) 是竹节参中的一种成分，对肾素renin 具有低抑制活性(IC50:77.4 μM)。
TN1343	8-Geranyloxypsoralen 8-香叶草氧基补骨脂素	Anti-infection; P450; BACE	Metabolism; Microbiology/Virology; Neuroscience
	8-Geranyloxypsoralen 是一种呋喃香豆素，分离自葡萄柚，是 P450 3A4 的有效抑制剂(IC50:3.93 μM)。
T0896	Furaltadone hydrochloride Furaltadone HCl,盐酸呋喃它酮	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Furaltadone hydrochloride (Furaltadone HCl) 是硝基呋喃药，可研究肠沙门氏菌感染，治疗球虫病。Furaltadone 具有体外抑制葡萄球菌作用。
T2S1907	Coniferaldehyde Ferulaldehyde,Ferulyl aldehyde,4-HYDROXY-3-METHOXYCINNAMALDEHYDE,松柏醛,Coniferyl aldehyde,松柏醛；4-羟基-3-甲氧基肉桂醛	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Coniferaldehyde (Ferulaldehyde) 是一种血红素加氧酶-1 的有效诱导剂，具有抗炎作用。在 RAW264.7 巨噬细胞中，它通过 PKCα/βII/Nrf-2/HO-1 依赖性途径来抑制 LPS 诱导的细胞凋亡。
T4918	DL-Glyceraldehyde Glyceric aldehyde,DL-甘油醛晶体	Reductase	Endocrinology/Hormones; Metabolism
	DL-Glyceraldehyde (Glyceric aldehyde) 是由酶甘油醛脱氢酶的作用产生的，该酶使用 NADP 作为辅因子将甘油转化为甘油醛。它是一种高活性化合物，可以修饰和交联蛋白质。
TN3694	Coniferaldehyde	NOS; COX; Nrf2; PKC; Autophagy	Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience
	Coniferaldehyde 能显着抑制酒球菌菌株的生长活力。 Coniferaldehyde 通过诱导血红素加氧酶 1 (HO-1) 发挥抗炎特性。
T5662	5-Hydroxy-1-tetralone	Others	Others
	5-hydroxy-1-tetralone 是一种荧光标记试剂，可用于生物样品中的鞘糖脂的测定。
T2826	Asaraldehyde Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde,细辛醛	COX	Immunology/Inflammation; Neuroscience
	Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde) 是COX-2抑制剂，能够明显降低环加氧酶 II (COX-2) 的活性(IC50:100 μg/mL)。
T3154	Citral Geranialdehyde,alpha-Citral,柠檬醛,geranial	Others	Others
	Citral (alpha-Citral) 是一种单萜，从柠檬草精油中获得，具有抗疼痛、抗炎作用。
TN1148	Isopsoralenoside	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Antibacterial	Endocrinology/Hormones; Microbiology/Virology
	Isopsoralenoside 是补骨脂多糖中的一种苯并呋喃苷。它在消化道内容物中可迅速代谢为补骨脂素。它具有雌激素样活性、促进成骨细胞增殖活性、抗肿瘤活性和抗菌活性。
TCP2934	5-Methylfurfural 5-Methyl furfural,5-Methyl-2-furaldehyde,5-甲基呋喃醛	Others	Others
	5-Methylfurfural (5-Methyl-2-furaldehyde) 是一种天然存在的调味剂，存在于香烟烟雾凝结物，烤土豆粉，甘草精油，储存的脱水橙粉，挥发性化合物的烤牛肉，香气浓缩的海绵蛋糕，咖啡，面包，茶和可可种。
TN5229	Vibralactone B	Antifection	Microbiology/Virology
	Vibralactone B shows antibacterial activity, it can inhibit significantly the growth of E. coli and Pseudomonas aeruginosa, with MBC values of 50 and 100 ug/mL, respectively.
TN4771	Phyltetralin
	Phyltetralin has antihyperuricemic activity.
TN2403	Glabralide B	Others	Others
	Glabralide B is a natural product from plants
T38478	Mevalonic acid 5-pyrophosphate tetralithium Mevalonicacid5-diphosphatetetralithium,Mevalonic acid 5-pyrophosphate tetralithium,5-Diphosphomevalonic acid tetralithium
	Mevalonic acid 5-pyrophosphate (also known as 5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite involved in the mevalonate pathway.
T14548	Beta-Zearalanol	Others	Others
	Beta-Zearalenol, a derivative of zearalenone (ZEA) capable of conjugating with glucuronic acid[2], is a mycotoxin produced by Fusarium spp. It induces apoptosis and oxidative stress in mammalian reproductive cells[1].
T79952	Kadsuralignan A
	Kadsuralignan A（化合物1）为从五味子（Schisandra lancifolia）叶和茎中分离的一种二苯并环辛二烯木脂素，显示出抗HIV活性，其EC50值为2.23 μg/mL。
TN3557	Cabraleadiol	ATPase; Antifection	Membrane transporter/Ion channel; Microbiology/Virology
	Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol inhibits photosystem II (PS II) and induces the appearance of small G band which is related wi
TN4591	Murralongin	Others	Others
	Murralongin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100.
TN3559	Cabraleahydroxylactone	HSV	Microbiology/Virology
	Cabraleahydroxylactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line.It shows antiviral activity against herpes simplex virus type-1 with an IC50 value of 3.20 ug/mL, in comparison with the standard acyclovir (IC50=1.90ug/mL).
T82282	Glycyuralin E
	Glycyuralin E，一种从Glycyrrhiza uralensis中可分离的天然化合物。
T67590	3-Furaldehyde
	3-Furaldehyde 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T67590，CAS号为 498-60-2。
TN3556	Cabraleadiol 3-acetate	Others	Others
	Cabraleadiol 3-acetate是一种天然产物，属于楝科米仔兰属，其产品编号为 TN3556，CAS号为 35833-62-6。Cabraleadiol 3-acetate可用作对照参考。
TN3560	Cabralealactone	Antifection	Microbiology/Virology
	Cabralealactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line, it is moderately active against a small-cell lung cancer (NCI-H187) cell line.
TN3267	8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen	Others	Others
	8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3267，CAS号为 144398-34-5。
TN2925	3-Epicabraleadiol	Others	Others
	3-Epicabraleadiol是一种天然产物，属于山茶科山茶属，其产品编号为 TN2925，CAS号为 19942-04-2。3-Epicabraleadiol可用作对照参考。
T13577	β-Zearalenol	Others	Others
	β-Zearalenol, a non-steroidal estrogenic mycotoxin synthesized by Fusarium species, potentially influences transcription and affects gene expression on the translational level.
TN3266	8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen	Others	Others
	8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3266，CAS号为 151121-39-0。
TN5251	Walsuralactam A	Others	Others
	Walsuralactam A in the formula I, which is used as an active ingredient, and is used for treating and preventing the tumour.
TN4128	Geraldol	Others	Others
	Geraldol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4128，CAS号为 21511-25-1。
TN4784	Picraline	SGLT	GPCR/G Protein
	A series of a hydroxy substituted derivatives 21-28 at C-17 of the Picraline-type alkaloids have been derived as having potent SGLT inhibitory activity.
T13551	Araliadiol	Others	Others
	Araliadiol is a polyacetylenic compound isolated from the leaves of Aralia cordata Thunb. Araliadiol inhibits MCF-7 cell growth (IC50: 6.41 µg/mL).
TN2926	3-Epicabraleahydroxylactone	Others	Others
	3-Epicabraleahydroxylactone has anti-tumor promoting effect, it has anti-carcinogenic activity by the inhibitory effect on the induction of Epstein-Barr virus early antigen(EBV-EA) by the tumor promoter.
T82278	Glyurallin B
	Glyurallin B, 一种黄酮类化合物，可从Glycyrrhiza infata和Glycyrrhiza uralensis中提取。该化合物展现出ABTS+自由基清除活性与脂质过氧化抑制活性，其EC50值分别为11.9 ± 0.58 μM和15.3 ± 1.26 μM。
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天然产物

Cat.No: T5625

Synonym: 玉米,Mycotoxin F2,玉米烯酮,RAL,F2 toxin,Toxin F2

Target: Others

Cat.No: TN1008

Target: CaMK, Calcium Channel, Histamine Receptor

Cat.No: T13542

Target: Estrogen Receptor/ERR

5-Hydroxymethylfurfural

Cat.No: T2943

Synonym: 5-羟甲基糠醛,2-Hydroxymethyl-5-furfural,2-Formyl-5-hydroxymethylfuran,5-Hydroxymethyl-2-furaldehyde,5-(Hydroxymethyl)furan-2-carbaldehyde

Target: Others, Antifungal

Isolinderalactone

Cat.No: T8213

Target: NOS, STAT

Cat.No: T1399

Synonym: Trichlorosucrose,三氯蔗糖,E955

Target: Others, Endogenous Metabolite

2-Methylbutyraldehyde

Cat.No: T5090

Synonym: 2-Ethylpropanal,RS)-2-Methylbutanal,2-甲基丁醛

Target: Others

Cat.No: T7921

Synonym: beta-Cyclocitral,β-环柠檬醛

Target: Others

Cat.No: T3S0289

Target: Calcium Channel

7-Methoxy-1-tetralone

Cat.No: Fr12275

Target: Others

Raloxifene hydrochloride

Cat.No: T1549

Synonym: LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl

Target: Estrogen Receptor/ERR, Others, MAO, Estrogen/progestogen Receptor, Autophagy

Cat.No: T2942

Synonym: Ficusin,Furocoumarin,补骨脂素,psoralene

Target: Apoptosis, Influenza Virus, HIV Protease, DNA/RNA Synthesis

Cat.No: T3399

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

Demethylzeylasteral

Cat.No: T3418

Synonym: 去甲泽拉木醛,Demethylzeylasteral (T-96)

Target: Apoptosis, UGT

Cat.No: T5657

Synonym: 3,4-Dimethoxybenzaldehyde,藜芦醛

Target: Antifungal

Cat.No: T5S1897

Target: Apoptosis, Others, JAK

Cat.No: T4S0290

Synonym: Chikusetsusaponin IV,竹节参皂苷IV

Target: RAAS, Fas/FasL

8-Geranyloxypsoralen

Cat.No: TN1343

Synonym: 8-香叶草氧基补骨脂素

Target: Anti-infection, P450, BACE

Furaltadone hydrochloride

Cat.No: T0896

Synonym: Furaltadone HCl,盐酸呋喃它酮

Target: Antibacterial, Antibiotic, Parasite

Coniferaldehyde

Cat.No: T2S1907

Synonym: Ferulaldehyde,Ferulyl aldehyde,4-HYDROXY-3-METHOXYCINNAMALDEHYDE,松柏醛,Coniferyl aldehyde,松柏醛；4-羟基-3-甲氧基肉桂醛

Target: Apoptosis, Antioxidant

DL-Glyceraldehyde

Cat.No: T4918

Synonym: Glyceric aldehyde,DL-甘油醛晶体

Target: Reductase

Coniferaldehyde

Cat.No: TN3694

Target: NOS, COX, Nrf2, PKC, Autophagy

5-Hydroxy-1-tetralone

Cat.No: T5662

Target: Others

Cat.No: T2826

Synonym: Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde,细辛醛

Target: COX

Cat.No: T3154

Synonym: Geranialdehyde,alpha-Citral,柠檬醛,geranial

Target: Others

Isopsoralenoside

Cat.No: TN1148

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Antibacterial

5-Methylfurfural

Cat.No: TCP2934

Synonym: 5-Methyl furfural,5-Methyl-2-furaldehyde,5-甲基呋喃醛

Target: Others

Cat.No: TN5229

Target: Antifection

Cat.No: TN4771

Cat.No: TN2403

Target: Others

Mevalonic acid 5-pyrophosphate tetralithium

Cat.No: T38478

Synonym: Mevalonicacid5-diphosphatetetralithium,Mevalonic acid 5-pyrophosphate tetralithium,5-Diphosphomevalonic acid tetralithium

Beta-Zearalanol

Cat.No: T14548

Target: Others

Kadsuralignan A

Cat.No: T79952

Cat.No: TN3557

Target: ATPase, Antifection

Cat.No: TN4591

Target: Others

Cabraleahydroxylactone

Cat.No: TN3559

Target: HSV

Cat.No: T82282

Cat.No: T67590

Cabraleadiol 3-acetate

Cat.No: TN3556

Target: Others

Cabralealactone

Cat.No: TN3560

Target: Antifection

8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen

Cat.No: TN3267

Target: Others

3-Epicabraleadiol

Cat.No: TN2925

Target: Others

Cat.No: T13577

Target: Others

8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen

Cat.No: TN3266

Target: Others

Walsuralactam A

Cat.No: TN5251

Target: Others

Cat.No: TN4128

Target: Others

Cat.No: TN4784

Target: SGLT

Cat.No: T13551

Target: Others

3-Epicabraleahydroxylactone

Cat.No: TN2926

Target: Others

Cat.No: T82278

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