首页工具

登录

搜索结果

Search Results for " nad "

158

抑制剂 & 化合物

42

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T83675	Thio-NAD Thionicotinamide NAD,Thionicotinamide adenine dinucleotide
	Thio-NAD是一种经硫酮改造的信号分子和酶辅因子NAD+的衍生物。它能够在碱性磷酸酶(ALP)酶活性检测中替代NAD+作为辅因子。Thio-NAD被用作双酶循环ELISA的底物，以识别严重急性呼吸综合征冠状病毒2（SARS-CoV-2)刺突糖蛋白，亦称为表面糖蛋白，以及患者痰液中的活M. tuberculosis细菌。其在405 nm处表现出吸收，使其能够与其他辅因子区分开来。
T83799	6-alkyne NAD+ sodium β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD
	6-炔基NAD+是一种可点击的信号分子及酶辅因子NAD+形式。它与荧光标签联用，用于检测聚(ADP-核糖)聚合酶(PARP)蛋白质底物。
T36304	Fluorescein-NAD+
	Fluoroscein NAD+ is a substrate for ADP-ribosylation, providing a convenient non-isotopic alternative to radiolabelled NAD for use in PARP assays. Allows direct measurement of NAD-dependent enzymes, such as PARP, by fluorescence microscopy. This product is a replacement for R&D Systems product 4673-500-01 81 μg is supplied as 250 μl of a 0.25 mM solution in water.
T33565	NAAD sodium salt NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD
	NAAD sodium salt (NAAD Na salt) 是烟酰胺腺嘌呤二核苷酸合酶的底物，可用于研究底物的特异性和动力学。
T23050	NAD 299 hydrochloride	Others	Others
	Selective, high affinity 5-HT1A receptor antagonist
T38730	Ara-F-NAD+
	Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.
T83845	8-(4-azidophenacylthio) NAD+ sodium Click Tag™ 8-(4-azidophenacylthio) NAD+,8-(4-azidophenacylthio) Nicotinamide adenine dinucleotide
	8-(4-azidophenacylthio) NAD+ 是NAD+信号分子及酶辅因子的一种可点击形式。
T83844	8-(2-azidobenzylthio) NAD+ sodium 8-(2-azidobenzylthio) Nicotinamide adenine dinucleotide,Click Tag™ 8-(2-azidobenzylthio) NAD+
	8-(2-azidobenzylthio) NAD+ 是一种可点击形式的信号分子及酶辅因子NAD+。
T75289	NAD sodium
	NAD sodium（β-Nicotinamide Adenine Dinucleotide sodium）为NAD的同类物，能在有机底物氧化反应中被还原为β-烟酰胺腺嘌呤二核苷酸（NADH）。此外，NAD sodium转化成的NADH能传递至线粒体内，间接促进ATP的生成。
T24721	Robalzotan NAD-299,AZD 7371,AZD7371,NAD 299,AZD-7371
	Robalzotan is a selective 5-HT1A receptor antagonist.
T78408	Nicotinamide 1,N6-ethenoadenine dinucleotide ε-NAD
	Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) 是一种NAD的荧光类似物，它可作为底物参与细菌毒素催化的信号转导G蛋白G-ADP核糖基化反应。此外，ε-NAD还常用作ADP核糖基化反应研究的荧光底物。
T31261	Deaminocozymase Deamino-NAD,Deamino DPN,Nicotinamide-hypoxanthine dinucleotide,Deamino NAD,Desamino-DPN
	Deaminocozymase also known as Nicotinamide-hypoxanthine dinucleotide, is a biochemical.
T76159	Aldehyde dehydrogenase (NAD(P))
	Aldehyde dehydrogenaseNAD(P) (ALDH) 催化醛氧化成相应的羧酸，伴随辅因子 NAD(P) 还原成 NAD(P)H，常用于生化研究。Aldehyde dehydrogenaseNAD(P) 是人体用来缓解乙醛应激的许多酶系统之一。
T73616	Glutamate dehydrogenase (NAD(P))
	Glutamate dehydrogenase NAD(P) (GLDH)（谷氨酸脱氢酶 NAD(P)）是一种存在于肝细胞、肾组织、脑、肌肉和肠细胞的线粒体酶，主要应用于生化研究。作为尿素循环的一环，该酶催化谷氨酸的逆向氧化脱氨反应，生成α-酮戊二酸（α-KG）。
T83800	6-Biotin-17-NAD+ sodium 6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide
	6-Biotin-17-NAD+ 是信号分子及酶辅因子NAD+的生物素化衍生物，已应用于高通量筛选(HTS)中，用于测定线粒体复合物I（又称NADH脱氢酶）的活性。
T74032	Ara-F-NAD+ sodium
	Ara-F-NAD+ sodium 是一种 NAD+的 arabino 类似物。Ara-F-NAD+ sodium 是一种有效的、可逆的、缓慢结合的CD38NADase 抑制剂。
T83798	8-bromo NAD+ sodium 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+
	8-bromo NAD+ 作为循环ADP-核糖（cADPR）抑制剂8-bromo cADPR的前药形式，通过CD38转化为8-bromo-cADPR。在1 mM浓度下，8-bromo NAD+ 阻止由N-formyl-Met-Leu-Phe (fMLP) 在分离的小鼠骨髓衍生的中性粒细胞内引起的细胞内钙水平增加和趋化作用。同时，在100 µM浓度下使用，减少了小鼠原代小胶质细胞中LPS诱导的亚硝酸盐产生以及TNF-α和IL-2的分泌。
T38163	ML-148	Dehydrogenase	Metabolism
	ML-148 是 15-羟基前列腺素脱氢酶 (15-PGDH, IC50 = 56 nM) 的特异性抑制剂。 ML-148 可用于分析一组相关的脱氢酶或还原酶以及有关前列腺素信号通路的研究。
T6912	NU1025 NSC 696807	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	NU1025 (NSC-696807) 是一种PARP 的有效抑制剂，IC50为 400 nM，Ki 为 48 nM。它可增强电离辐射和抗癌药物的细胞毒性，有抗癌和神经保护的作用。
T12854	SBI-797812	NAMPT	Metabolism
	SBI-797812 是在结构上类似于活性位点定向的 NAMPT 抑制剂的化合物，能够阻断这些抑制剂与 NAMPT 的结合。它将 NAMPT 反应平衡转向 NMN 形成，提高 NAMPT 对 ATP 的亲和力，稳定 His247 处的磷酸化 NAMPT，增加焦磷酸盐副产物的消耗，并通过 NAD+钝化反馈抑制。
T77092	Nadecnemab REGN-5069	Others	Others
	Nadecnemab 是一种靶向胶质细胞源性神经营养因子家族受体 GFRA3 的 IgG4κ 抗体。Nadecnemab 可用于膝骨关节炎和神经系统疾病。
T31091	CRANAD-28 CRANAD28	Others	Others
	CRANAD-28 是一种血脑屏障（BBB）穿透型双光子成像探头，能够显示淀粉样蛋白斑块，可以标记斑块和脑淀粉样血管病。
T22276	Bis(maltolato)oxovanadium(IV) 双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)	Phosphatase; Others	Metabolism; Others
	Bis(maltolato)oxovanadium(IV) (BMOV) 是一种有效的胰岛素增敏剂，也是一种有效的、竞争性的、可逆的、口服具有活性的光谱蛋白酪氨酸磷酸酶 (PTP) 抑制剂。它抑制HCPTPA，PTP1B，HPTPβ和SHP2的IC50分别为 126 nM，109 nM，26 nM 和 201 nM。
T1470L	Fexofenadine hydrochloride	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Fexofenadine hydrochloride 是 terfenadine 的羧化代谢衍生物和长效选择性组胺 H1 受体拮抗剂，具有抗组胺活性。
T6618	Orphenadrine Citrate Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君	AChR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Orphenadrine Citrate (Flexon) 是NMDA 受体拮抗剂，Ki 为6.0μM，还是HERG 钾离子通道阻断剂。它是一种骨骼肌松弛剂，它作用于中枢神经系统以产生肌肉松弛作用。
T7092	NADPH tetrasodium salt	Others; Ferroptosis; Endogenous Metabolite	Apoptosis; Metabolism; Others
	NADPH tetrasodium salt 是电子受体烟酰胺腺嘌呤二核苷酸磷酸的还原形式，在各种生物反应中充当电子供体。NADPH tetrasodium salt 也是一种内源性铁死亡抑制剂。
T68599	Orphenadrine Orphenadrine (free base)	Sodium Channel; NMDAR; AChR	Membrane transporter/Ion channel; Neuroscience
	Orphenadrine 是一种非竞争性的 N-甲基-D-天冬氨酸（NMDA）受体拮抗剂，以浓度依赖性方式抑制克隆的 HERG 通道，在 HEK 细胞中产生0.85μM 的 IC。Orphenadrine 是中枢和外周毒蕈碱受体的拮抗剂，通过孔残基 Y652或 F656突变阻断衰减。 Orphenadrine 具有抗痉挛、镇痛和抗胆碱能活性，对在体外和体内对谷氨酸神经毒性具有保护作用。Orphenadrine 对钠离子通道具有抑制作用，可用来治疗帕金森。
T68127	Picenadol LY-150720,LY150720,LY 150720	Others	Others
	Picenadol (LY 150720) 是N-甲基-4-苯基哌啶衍生物的外消旋混合物，具有激动剂 - 拮抗剂阿片性质。Picenadol 具有中枢镇痛活性。
T28294	Panadiplon FG10571,FG-10571,FD-10571,PNU 78875,FG 10571,FD10571,FD 10571	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Panadiplon (FG 10571) 是一种具有选择性的γ-氨基丁酸受体激动剂和5GABAA 的部分激动剂，是一种苯二氮卓类受体，可用于治疗焦虑症。Panadiplon 对 5GABAA 受体与 1GABAA 受体表现出选择性。
T27627	Iroxanadine BRX005,BRX-235,BRX-005,BRX235,BRX 005,BRX 235	p38 MAPK	MAPK
	Iroxanadine (BRX-005) 是一种新型小分子MAPK p38 抑制剂，诱导p38 SAPK 的磷酸化，在用去氧肾上腺素预先收缩的豚鼠肺动脉制剂中诱导浓度依赖性松弛，可用于治疗动脉粥样硬化、糖尿病血管病，微血管心绞痛和外周动脉疾病等血管疾病。
T2189	Sodium orthovanadate Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate	ATPase; Phosphatase	Membrane transporter/Ion channel; Metabolism
	Sodium orthovanadate 是一种蛋白酪氨酸磷酸酶，碱性磷酸酶和一些ATP 酶的抑制剂，有可能充当磷酸盐类似物。它具有胰岛素样作用、对心室肌的正性肌力作用和其他代谢作用。
T16980	Taminadenant	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Taminadenant 是一种腺苷受体拮抗剂。
T5963	Menadione bisulfite sodium Sodium menadione bisulfite,亚硫酸氢钠甲萘醌,Menadione sodium bisulfite,Vitamin K3 sodium bisulfite	Others	Others
	Menadione bisulfite sodium (Vitamin K3 sodium bisulfite) 是可以诱导急性氧化应激的试剂，可用作植物防御活化剂，具有抵抗病菌的作用。
T12005	meta-Fexofenadine meta-MDL-16455,meta-Terfenadine carboxylate,Fexofenadine impurity B	Drug Metabolite	Metabolism
	meta-Fexofenadine (meta-MDL-16455) 是 Fexofenadine 的异构体。
T8833	2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid	Others	Others
	2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid 可用于合成多种有机化合物。
T22694	CRANAD 2	Others	Others
	CRANAD 2 是一种特异性近红外 (NIR) 荧光探针，可用于检测 Aβ 斑块。它可透过血脑屏障，且对 Aβ 聚集体有高亲和性，其 Kd=38 nM。
T21390	Fexofenadine Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Fexofenadine (Carboxyterfenadine) 是一种抗组胺药物，用于治疗过敏症状，如鼻塞、花粉热和荨麻疹。与第一代抗组胺药相比，它通过血脑屏障并引起镇静的能力较差。
T1308	Orphenadrine hydrochloride Mebedrol,Mephenamin,盐酸邻甲苯海拉明	Sodium Channel; NMDAR; Norepinephrine; iGluR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Orphenadrine hydrochloride (Mephenamin) 是一种非竞争性的NMDA 受体拮抗剂, Ki=6.0 ± 0.7 μM。
T2644	(E)-Daporinad Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈	NAMPT; Transferase; Autophagy	Autophagy; Metabolism
	(E)-Daporinad (FK866) 是一种烟酰胺磷酸核糖基转移酶的小分子抑制剂，具有潜在的抗肿瘤和抗血管生成活性，IC50为 0.09 nM。
T5015	Gonadorelin Acetate (33515-09-2 free base) 醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate	Reductase	Endocrinology/Hormones; Metabolism
	Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) 是下丘脑神经肽，在控制生殖功能中起关键作用。
T1470	Fexofenadine hydrochloride Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,盐酸非索非那定,Telfast,Fexofenadine HCl,Allegra,MDL 16455A	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) 是一种抗组胺药，用于治疗过敏性鼻炎、血管性水肿和慢性荨麻疹。
T67826	Alalevonadifloxacin	DNA gyrase; Topoisomerase; Antibacterial	DNA Damage/DNA Repair; Microbiology/Virology
	Alalevonadifloxacin 是一种DNA 回旋酶和DNA 拓扑异构酶抑制剂，是一种喹诺酮类针对Mrsa 的新型抗菌化合物。Alalevonadifloxacin 对治疗细菌性革兰氏阳性、革兰氏阴性和厌氧性感染有潜在作用。
T9430	Venadaparib NOV140101,IDX-1197	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Venadaparib (NOV140101) 是一种选择性和具有口服活性的 PARP 抑制剂，对 PARP1和 PARP2的 IC50分别为 1.4 和 1.0 nM。它可防止 DNA 单链断裂 (SSB) 的修复，可研究实体瘤。
T26254	Teglarinad chloride GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride	NAMPT	Metabolism
	Teglarinad chloride (GMX-1777 chloride) 是一种有效的 NAMPT 的抑制剂，是 GMX1778 的前体。Teglarinad chloride 具有抗肿瘤活性，通过干扰 DNA 修复和抑制血管生成来发挥作用。
T1266	Terfenadine (±)-Terfenadine,特非那定,MDL-991	Apoptosis; Potassium Channel; 5-HT Receptor; Caspase; Na+/Ca2+ Exchanger; HER; AChR; Histamine Receptor	Angiogenesis; Apoptosis; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Terfenadine ((±)-Terfenadine) 是一种hERG 开放通道抑制剂，IC50为 204 nM。它也是一种 H1 组胺受体拮抗剂，通过调节Ca2+稳态在黑素瘤细胞中起到有效的细胞凋亡诱导作用。 Terfenadine 诱导 ROS 依赖性细胞凋亡，同时激活Caspase-4，-2，-9。
T6851	NADP sodium salt Sodium NADP,三磷酸吡定核苷酸,辅酶Ⅱ(NADP 钠盐)	Others	Others
	NADP sodium salt (Sodium NADP) 是一种烟酰胺腺嘌呤二核苷酸，是一种氧化还原辅助因子。它是代谢中电子转移的关键辅因子，能够被交替氧化 (NADP+) 和还原 (NADPH)。
T1466	Nadifloxacin OPC7251,那氟沙星	Antibacterial; Antibiotic	Microbiology/Virology
	Nadifloxacin (OPC7251) 是一种对粉刺有效的广谱氟喹诺酮类抗生素。
T19467	NADPH tetracyclohexanamine 还原型辅酶II四钠,NADPH (tetracyclohexanamine)	Ferroptosis	Apoptosis
	NADPH tetracyclohexanamine (NADPH(tetracyclohexanamine)) 是一种辅助因子和生物还原剂。
T36066	NADP+ (sodium salt hydrate)
	NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the maintenance of redox status, and intracellular signaling. For example, binding of NADP+ to β-subunits of Kv channels activates ion transport, whereas NADPH stabilizes channel inactivation. NADP+ is biosynth...
T64752	2,2,3,3-Tetramethyl-4,7,10,13,16-pentaoxa-3-silanonadec-18-yne
	2,2,3,3-Tetramethyl-4,7,10,13,16-pentaoxa-3-silanonadec-18-yne 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64752。

化合物

Cat.No: T83675

Synonym: Thionicotinamide NAD,Thionicotinamide adenine dinucleotide

6-alkyne NAD+ sodium

Cat.No: T83799

Synonym: β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD

Fluorescein-NAD+

Cat.No: T36304

NAAD sodium salt

Cat.No: T33565

Synonym: NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD

NAD 299 hydrochloride

Cat.No: T23050

Target: Others

Cat.No: T38730

8-(4-azidophenacylthio) NAD+ sodium

Cat.No: T83845

Synonym: Click Tag™ 8-(4-azidophenacylthio) NAD+,8-(4-azidophenacylthio) Nicotinamide adenine dinucleotide

8-(2-azidobenzylthio) NAD+ sodium

Cat.No: T83844

Synonym: 8-(2-azidobenzylthio) Nicotinamide adenine dinucleotide,Click Tag™ 8-(2-azidobenzylthio) NAD+

Cat.No: T75289

Cat.No: T24721

Synonym: NAD-299,AZD 7371,AZD7371,NAD 299,AZD-7371

Nicotinamide 1,N6-ethenoadenine dinucleotide

Cat.No: T78408

Synonym: ε-NAD

Deaminocozymase

Cat.No: T31261

Synonym: Deamino-NAD,Deamino DPN,Nicotinamide-hypoxanthine dinucleotide,Deamino NAD,Desamino-DPN

Aldehyde dehydrogenase (NAD(P))

Cat.No: T76159

Glutamate dehydrogenase (NAD(P))

Cat.No: T73616

6-Biotin-17-NAD+ sodium

Cat.No: T83800

Synonym: 6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide

Ara-F-NAD+ sodium

Cat.No: T74032

8-bromo NAD+ sodium

Cat.No: T83798

Synonym: 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+

Cat.No: T38163

Target: Dehydrogenase

Cat.No: T6912

Synonym: NSC 696807

Target: PARP

Cat.No: T12854

Target: NAMPT

Cat.No: T77092

Synonym: REGN-5069

Target: Others

Cat.No: T31091

Synonym: CRANAD28

Target: Others

Bis(maltolato)oxovanadium(IV)

Cat.No: T22276

Synonym: 双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)

Target: Phosphatase, Others

Fexofenadine hydrochloride

Cat.No: T1470L

Target: Histamine Receptor

Orphenadrine Citrate

Cat.No: T6618

Synonym: Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君

Target: AChR, iGluR

NADPH tetrasodium salt

Cat.No: T7092

Target: Others, Ferroptosis, Endogenous Metabolite

Cat.No: T68599

Synonym: Orphenadrine (free base)

Target: Sodium Channel, NMDAR, AChR

Cat.No: T68127

Synonym: LY-150720,LY150720,LY 150720

Target: Others

Cat.No: T28294

Synonym: FG10571,FG-10571,FD-10571,PNU 78875,FG 10571,FD10571,FD 10571

Target: GABA Receptor

Cat.No: T27627

Synonym: BRX005,BRX-235,BRX-005,BRX235,BRX 005,BRX 235

Target: p38 MAPK

Sodium orthovanadate

Cat.No: T2189

Synonym: Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate

Target: ATPase, Phosphatase

Cat.No: T16980

Target: Adenosine Receptor

Menadione bisulfite sodium

Cat.No: T5963

Synonym: Sodium menadione bisulfite,亚硫酸氢钠甲萘醌,Menadione sodium bisulfite,Vitamin K3 sodium bisulfite

Target: Others

meta-Fexofenadine

Cat.No: T12005

Synonym: meta-MDL-16455,meta-Terfenadine carboxylate,Fexofenadine impurity B

Target: Drug Metabolite

2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid

Cat.No: T8833

Target: Others

Cat.No: T22694

Target: Others

Cat.No: T21390

Synonym: Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra

Target: Histamine Receptor

Orphenadrine hydrochloride

Cat.No: T1308

Synonym: Mebedrol,Mephenamin,盐酸邻甲苯海拉明

Target: Sodium Channel, NMDAR, Norepinephrine, iGluR, Histamine Receptor

Cat.No: T2644

Synonym: Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈

Target: NAMPT, Transferase, Autophagy

Gonadorelin Acetate (33515-09-2 free base)

Cat.No: T5015

Synonym: 醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate

Target: Reductase

Fexofenadine hydrochloride

Cat.No: T1470

Synonym: Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,盐酸非索非那定,Telfast,Fexofenadine HCl,Allegra,MDL 16455A

Target: Histamine Receptor

Alalevonadifloxacin

Cat.No: T67826

Target: DNA gyrase, Topoisomerase, Antibacterial

Cat.No: T9430

Synonym: NOV140101,IDX-1197

Target: PARP

Teglarinad chloride

Cat.No: T26254

Synonym: GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride

Target: NAMPT

Cat.No: T1266

Synonym: (±)-Terfenadine,特非那定,MDL-991

Target: Apoptosis, Potassium Channel, 5-HT Receptor, Caspase, Na+/Ca2+ Exchanger, HER, AChR, Histamine Receptor

NADP sodium salt

Cat.No: T6851

Synonym: Sodium NADP,三磷酸吡定核苷酸,辅酶Ⅱ(NADP 钠盐)

Target: Others

Cat.No: T1466

Synonym: OPC7251,那氟沙星

Target: Antibacterial, Antibiotic

NADPH tetracyclohexanamine

Cat.No: T19467

Synonym: 还原型辅酶II四钠,NADPH (tetracyclohexanamine)

Target: Ferroptosis

NADP+ (sodium salt hydrate)

Cat.No: T36066

2,2,3,3-Tetramethyl-4,7,10,13,16-pentaoxa-3-silanonadec-18-yne

Cat.No: T64752

Cat. No.	Product Name	Target	Signaling Pathways
T1609	NAD+ 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD	NADPH; Endogenous Metabolite	Metabolism
	NAD+ (β-Nicotinamide Adenine Dinucleotide) 即烟酰胺腺嘌呤二核苷酸，是转递氢离子的辅酶。
TN2252	Syrosingopine	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Syrosingopine 是 MCT1和 MCT4双重抑制剂，对 MCT4 的效力高 60 倍，可防止乳酸和 H+ 流出。它是可口服抗高血压药物，联合二甲双胍具有研究癌症疾病的潜力。
T13795	Nicotinamide riboside	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Nicotinamide riboside 是维生素 B3 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体，增加 NAD+水平并激活SIRT1和SIRT3，可用于研究阿尔茨海默氏病的认知退化。
T6220	Nicotinamide riboside chloride 烟酰胺核糖氯酸盐,烟酰胺核苷	Sirtuin; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nicotinamide riboside Chloride 是维生素 B3 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体，增加 NAD+水平并激活SIRT1和SIRT3，可用于研究阿尔茨海默氏病的认知退化。
T4721	β-Nicotinamide mononucleotide β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸	Others; Endogenous Metabolite	Metabolism; Others
	β-Nicotinamide mononucleotide (β-NM) 是烟酰胺磷酸核糖转移酶 (NAMPT) 反应的产物。β-nicotinamide mononucleotide 的作用包括其在细胞生化功能、心脏保护、糖尿病、肥胖相关并发症和阿尔茨海默病中的作用。
T8150	Nudifloramide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺	PARP; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) 是烟酰胺-腺嘌呤二核苷酸(NAD) 降解的一种最终产物，可显著抑制PARP-1活性。
T5283	NADH disodium salt Disodium NADH,NADH, disodium salt hydrate,beta-烟酰胺腺嘌呤二核苷二钠	Others; Endogenous Metabolite	Metabolism; Others
	NADH disodium salt (Disodium NADH) hydrate 是氧化还原酶的辅酶。NADH disodium salt hydrate 在分解代谢过程中起到再生电子供体的作用，包括糖酵解，柠檬酸循环和β-氧化。
T8067	Methyl Nonadecanoate Nonadecanoic Acid methyl ester,正十九酸甲酯	Others	Others
	Methyl Nonadecanoate (Nonadecanoic Acid methyl ester)是一种内标物，能够用于生物柴油中脂肪酸甲酯含量的测定。
T0449	Menadione 维生素K3,Vitamin K3,甲萘醌	Thrombin; Endogenous Metabolite	Metabolism; Proteases/Proteasome
	Menadione (Vitamin K3) 是合成的萘醌，能够在体内转化成活性维生素 K2。
TN6754	1-Nonadecanol	Others	Others
	1-Nonadecanol 是一种 Heracleum thomsonii 的超临界二氧化碳精油的成分，也是 Neotinea ustulata 的重要香气化合物。
TN7148	Mukanadin C 7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one	Others	Others
	Mukanadin C (7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one) 是一种海洋来源的天然产物，存在于 Stylissa carteri。
T8070	Nonadecanoic acid	Others	Others
	Nonadecanoic acid 是19 C 长的饱和脂肪酸，是白蚁防御时分泌的主要物质。
T3373	Columbianadin Zosimin,2-Butenoic acid,二氢欧山芹醇当归酸酯	Apoptosis	Apoptosis
	Columbianadin (Zosimin) 是来自当归的根的主要生物活性成分之一，是一种天然香豆素，具有抗炎和抗癌作用。
T22446	NADP disodium salt Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐	Others	Others
	NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子，是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子，可以被交替氧化 (NADP+) 和还原 (NADPH)。
T8271	10Z-Nonadecenoic acid	Endogenous Metabolite	Metabolism
	10Z-Nonadecenoic acid 是一种长链脂肪酸，具有抗肿瘤特性。
TN3253	7alpha-Hydroxy-4,11-cadinadiene-3,8-dione	Others	Others
	7alpha-Hydroxy-4,11-cadinadiene-3,8-dione 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3253，CAS号为 1423809-64-6。
T4448	NADP
	NADP，也称为烟酰胺腺嘌呤二核苷酸磷酸，是各种代谢过程中电子转移所必需的重要氧化还原辅因子。它在促进细胞能量产生和维持细胞内氧化还原平衡方面发挥着关键作用。
TN3308	9(11),12-Oleanadien-3-ol	Others	Others
	9(11),12-Oleanadien-3-ol is a natural product from Euonymus maackii.
TN4200	Hennadiol	Others	Others
	Hennadiol是一种天然产物，属于大戟科野桐属，其产品编号为 TN4200，CAS号为 20065-99-0。Hennadiol可用作对照参考。
T75459	Canadensolide
	Canadensolide 是一种 Penicillium canadense 的抗真菌代谢产物。
TN2916	3-Acetoxy-4,7(11)-cadinadien-8-one	Others	Others
	3-Acetoxy-4,7(11)-cadinadien-8-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2916，CAS号为 104975-02-2。
TN3574	Canadine	P450	Metabolism
	Canadine has antioxidant activity with low-toxic effect.
TN3108	5-Epicanadensene	Others	Others
	5-Epicanadensene is a natural product from Taxus sumatrana.
TN7037	(Z)-9-nonadecene 9-Nonadecene	Others	Others
	(Z)-9-nonadecene (9-Nonadecene) 首次在 T. melanocephalum 中被发现。它是下颌腺中的主要成分，而虹膜在尾腺中产生。
TN3129	5-Nonadecylresorcinol	Others	Others
	5-Nonadecylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells.
TQ0190	D-Xylulose	Others; Endogenous Metabolite	Metabolism; Others
	D-xylulose 通过葡萄糖醛酸途径中的酶 NAD+ 连接的木糖醇脱氢酶从木糖醇转化，葡萄糖醛酸途径是哺乳动物中重要的木糖醇处理代谢途径。
T0064	Adenine Vitamin B4,腺嘌呤,6-Aminopurine	DNA/RNA Synthesis; Endogenous Metabolite; AChR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Neuroscience
	Adenine (6-Aminopurine) 是一种嘌呤衍生物，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T0617	Nicotinamide N-oxide Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide	c-Myc; Endogenous Metabolite; CXCR; Drug Metabolite	Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; Immunology/Inflammation; Metabolism
	Nicotinamide N-oxide (Nicotinamide 1-oxide) 是生物体内烟酰胺分解代谢物，是高效选择性CXCR2受体拮抗剂。
T4728	4-Acetamidobutanoic acid N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸	GABA Receptor; Endogenous Metabolite; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) 可在血液、粪便和尿液以及人体前列腺组织中找到，也存在于从酵母到人类的所有真核生物中。它是GABA 衍生物，具有抗氧化和抗菌活性。
T0879	Niacin Vitamin B3,烟酸(维生素B3),Nicotinic acid	Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Niacin (Nicotinic acid)，也称为烟酸和维生素 B3，是一种水溶性必需的 B 族维生素，用于治疗维生素缺乏症以及高脂血症，血脂异常，高甘油三酯血症，并降低心肌梗塞的风险
T6369	Adenine hemisulfate 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hemisulfate (Diadenine sulphate) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T6225	Adenine hydrochloride Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T1353	DL-Mevalonolactone 甲瓦龙酸内酯,Mevalonolactone	Others; Endogenous Metabolite	Metabolism; Others
	DL-Mevalonolactone (Mevalonolactone)，一种人内源性代谢物，是甲羟戊酸的 δ-lactone 形式，甲羟戊酸途径的一个前体。它能够降低大脑中线粒体膜电位(∆Ψm)，Ca2+的保留能力和 NAD (P) H 的含量 , 而且还诱导线粒体肿胀。
T0809	Dicoumarol Dicumarol,双羟香豆素,双香豆素	Dehydrogenase; NADPH; PDK	Metabolism; PI3K/Akt/mTOR signaling
	Dicoumarol (Dicumarol) 是一种 NAD(P)H: 醌氧化还原酶 1 和PDK1的抑制剂，它们的IC50值分别为 0.37 和 19.42 μM。
T19477	Nicotinic acid mononucleotide	Others	Others
	Nicotinic acid mononucleotide is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+.
T13870	Riboflavine phosphate Riboflavine 5'-phosphate	Endogenous Metabolite	Metabolism
	Riboflavine phosphate （Flavin mononucleotide）是 Riboflavin 的衍生物。Riboflavin phosphate 可用于研究圆锥角膜、角膜扩张、不规则散光。Riboflavine phosphate 是一种高效经济的 NAD+ 回收剂。
T19253	Cyclic ADP-ribose cADPR	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release
T37687	Cyclic ADP-ribose ammonium
	Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-mediated release from the endoplasmic reticulum, while also facilitating extracellular influx through the opening of TRPM2 channels [1][2][3].
T0879L	Niacin hydrochloride
	Niacin hydrochloride is a water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is needed by the body for the formation of coenzymes NAD and NADP. It possesses PELLAGRA-curative, vasodilating, and antilipemic properties.
TN1208	2-Amino-3-carboxy-1,4-naphthoquinone	NADPH-oxidase	Immunology/Inflammation
	2-Amino-3-carboxy-1,4-naphthoquinone 是电子转移介质，可改变同型发酵乳酸菌的葡萄糖代谢，可作为双歧杆菌生长刺激剂，它通过NAD(P)H 介导的氧化作用影响双歧杆菌的终产物形态。
TN3806	Dehydroglyasperin C	ERK; IκB/IKK; p38 MAPK; TNF; NF-κB; Akt; COX; PI3K; NADPH; DNA/RNA Synthesis; Nrf2; JNK; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
	Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases
T37911	cis-Resveratrol 顺式白藜芦醇,(Z)-Resveratrol
	Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the &#181M range similar to that observed with trans-resveratrol. It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase ...

天然产物

Cat.No: T1609

Synonym: 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD

Target: NADPH, Endogenous Metabolite

Cat.No: TN2252

Target: Dopamine Receptor

Nicotinamide riboside

Cat.No: T13795

Target: Sirtuin

Nicotinamide riboside chloride

Cat.No: T6220

Synonym: 烟酰胺核糖氯酸盐,烟酰胺核苷

Target: Sirtuin, Endogenous Metabolite

β-Nicotinamide mononucleotide

Cat.No: T4721

Synonym: β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸

Target: Others, Endogenous Metabolite

Cat.No: T8150

Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺

Target: PARP, Endogenous Metabolite

NADH disodium salt

Cat.No: T5283

Synonym: Disodium NADH,NADH, disodium salt hydrate,beta-烟酰胺腺嘌呤二核苷二钠

Target: Others, Endogenous Metabolite

Methyl Nonadecanoate

Cat.No: T8067

Synonym: Nonadecanoic Acid methyl ester,正十九酸甲酯

Target: Others

Cat.No: T0449

Synonym: 维生素K3,Vitamin K3,甲萘醌

Target: Thrombin, Endogenous Metabolite

Cat.No: TN6754

Target: Others

Cat.No: TN7148

Synonym: 7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one

Target: Others

Nonadecanoic acid

Cat.No: T8070

Target: Others

Cat.No: T3373

Synonym: Zosimin,2-Butenoic acid,二氢欧山芹醇当归酸酯

Target: Apoptosis

NADP disodium salt

Cat.No: T22446

Synonym: Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐

Target: Others

10Z-Nonadecenoic acid

Cat.No: T8271

Target: Endogenous Metabolite

7alpha-Hydroxy-4,11-cadinadiene-3,8-dione

Cat.No: TN3253

Target: Others

Cat.No: T4448

9(11),12-Oleanadien-3-ol

Cat.No: TN3308

Target: Others

Cat.No: TN4200

Target: Others

Cat.No: T75459

3-Acetoxy-4,7(11)-cadinadien-8-one

Cat.No: TN2916

Target: Others

Cat.No: TN3574

Target: P450

5-Epicanadensene

Cat.No: TN3108

Target: Others

(Z)-9-nonadecene

Cat.No: TN7037

Synonym: 9-Nonadecene

Target: Others

5-Nonadecylresorcinol

Cat.No: TN3129

Target: Others

Cat.No: TQ0190

Target: Others, Endogenous Metabolite

Cat.No: T0064

Synonym: Vitamin B4,腺嘌呤,6-Aminopurine

Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR

Nicotinamide N-oxide

Cat.No: T0617

Synonym: Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide

Target: c-Myc, Endogenous Metabolite, CXCR, Drug Metabolite

4-Acetamidobutanoic acid

Cat.No: T4728

Synonym: N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸

Target: GABA Receptor, Endogenous Metabolite, Antibacterial

Cat.No: T0879

Synonym: Vitamin B3,烟酸(维生素B3),Nicotinic acid

Target: Endogenous Metabolite, Autophagy

Adenine hemisulfate

Cat.No: T6369

Synonym: 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐

Target: DNA/RNA Synthesis, Endogenous Metabolite

Adenine hydrochloride

Cat.No: T6225

Synonym: Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride

Target: DNA/RNA Synthesis, Endogenous Metabolite

DL-Mevalonolactone

Cat.No: T1353

Synonym: 甲瓦龙酸内酯,Mevalonolactone

Target: Others, Endogenous Metabolite

Cat.No: T0809

Synonym: Dicumarol,双羟香豆素,双香豆素

Target: Dehydrogenase, NADPH, PDK

Nicotinic acid mononucleotide

Cat.No: T19477

Target: Others

Riboflavine phosphate

Cat.No: T13870

Synonym: Riboflavine 5'-phosphate

Target: Endogenous Metabolite

Cyclic ADP-ribose

Cat.No: T19253

Synonym: cADPR

Target: Calcium Channel

Cyclic ADP-ribose ammonium

Cat.No: T37687

Niacin hydrochloride

Cat.No: T0879L

2-Amino-3-carboxy-1,4-naphthoquinone

Cat.No: TN1208

Target: NADPH-oxidase

Dehydroglyasperin C

Cat.No: TN3806

Target: ERK, IκB/IKK, p38 MAPK, TNF, NF-κB, Akt, COX, PI3K, NADPH, DNA/RNA Synthesis, Nrf2, JNK, Autophagy

cis-Resveratrol

Cat.No: T37911

Synonym: 顺式白藜芦醇,(Z)-Resveratrol

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼