keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) 是下丘脑神经肽,在控制生殖功能中起关键作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 313 | 现货 | ||
5 mg | ¥ 727 | 现货 | ||
10 mg | ¥ 1,290 | 现货 | ||
25 mg | ¥ 2,620 | 现货 | ||
50 mg | ¥ 3,670 | 现货 | ||
100 mg | ¥ 5,150 | 现货 | ||
500 mg | ¥ 10,800 | 现货 |
产品描述 | Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) is hypothalamic neuropeptide which plays a key role in the control of reproductive functions. |
体外活性 | Luteinizing Hormone Releasing Hormone (LH-RH), also called gonadotropin-releasing hormone (GnRH), is the primary link between the brain, the pituitary and gonadal function, and has a key role in vertebrate reproduction. The endocrine actions of Luteinizing Hormone Releasing Hormone (LH-RH) and its analogs are mediated by high-affinity membrane receptors for LHRH on pituitary gonadotrophs. LHRH is expressed,together with its receptors,in hormonerelated tumors such as prostate cancer,to act as a local autocrine/paracrine growth inhibitory factor. In prostate cancer cells,the LHRH receptor is coupled to the Gi-cAMP pathway to inhibit cell proliferation. |
体内活性 | Luteinizing Hormone Releasing Hormone treatment advances the timing of vaginal opening by 5 days, which is used as an initial indicator for the time of puberty. |
动物实验 | Rat:Immature female Sprague-Dawley rats receive either 50 ng Luteinizing Hormone Releasing Hormone (LH-RH)/kg BW or 20 mg NMA/kg BW in a 10% dextrose, 0.9% NaCl solution, while controls receive only vehicle. After completion of the treatment, rats are examined daily for vaginal opening. |
别名 | 醋酸戈那瑞林, Luteinizing Hormone Releasing Hormone (LH-RH), Luteinizing Hormone Releasing Hormone (LH-RH), human, Gonadorelin Acetate |
分子量 | 1302.39 |
分子式 | C59H83N17O17 |
CAS No. | 71447-49-9 |
keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 0.7678 mL | 3.8391 mL | 7.6782 mL | 19.1955 mL |
5 mM | 0.1536 mL | 0.7678 mL | 1.5356 mL | 3.8391 mL | |
10 mM | 0.0768 mL | 0.3839 mL | 0.7678 mL | 1.9195 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Gonadorelin Acetate (33515-09-2 free base) 71447-49-9 Endocrinology/Hormones Metabolism Reductase Gonadorelin Acetate (33515092 free base) 醋酸戈那瑞林 Luteinizing Hormone Releasing Hormone (LH-RH) 33515-09-2 Luteinizing Hormone Releasing Hormone (LH-RH), human 33515-09-2 free base Gonadorelin Acetate (33515 09 2 free base) Luteinizing Hormone Releasing Hormone Gonadorelin Acetate LH-RH Inhibitor inhibitor inhibit