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Search Results for " ca-1 "

Targets Recommended: HIV Protease

83

抑制剂 & 化合物

14

天然产物

1744

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10658	CA inhibitor 1 GS-6207 analog	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.
T10659	Ca2+ channel agonist 1	Calcium Channel; CDK	Cell Cycle/Checkpoint; Membrane transporter/Ion channel; Metabolism
	Ca2+channel agonist 1 是 N-型钙离子通道激动剂和Cdk2的抑制剂，EC50分别为 14.23 μM 和 3.34 μM，可用作运动神经末梢功能障碍的潜在治疗方法。
T9027	CA-4948 Emavusertib	IRAK; FLT	Angiogenesis; Immunology/Inflammation; NF-κB; Tyrosine Kinase/Adaptors
	CA-4948 (Emavusertib) 是一种IRAK4抑制剂，也是一种FLT3抑制剂，具有抗肿瘤作用。
T5354	IRAK4-IN-7 CA-4948	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂，口服有活性。它可用于研究癌症以及炎症疾病。
T10690	Cav 2.2 blocker 1	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cav 2.2 blocker 1 是一种N 型钙离子通道 (Cav 2.2) 的阻断剂，IC50值为 1 nM，可用于治疗疼痛。
T16873	SERCA2a activator 1	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	SERCA2a activator 1 是一种肌肉/内质网 Ca2+ 依赖性 ATPase 2a 激活剂。 SERCA2a activator 1 降低受磷蛋白抑制并增强心脏的收缩和舒张功能。
T12378L	CA-170 PD-1-IN-1	Others	Others
	PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.
T7334	NP118809 39-1B4,1-【4-(二苯甲基)-1-哌嗪基】-3,3-二苯基-1-丙酮	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	NP118809 (39-1B4) 是 N 型钙通道阻滞剂，IC50值为 0.11 μM。它较弱地抑制 L 型钙通道，IC50值为 12.2 μM。
T60012	HS-243	IRAK; MAPK; CDK	Cell Cycle/Checkpoint; Immunology/Inflammation; MAPK; NF-κB
	HS-243 是 IRAK-4 和 IRAK-1 的抑制剂，IC50 分别为 20 和 24 nM。 HS-243 显示出抗炎和抗癌活性。
T20656	Verapamil NSC 135784,维拉帕米,NSC-135784,CP-16533-1,(±)-Verapamil	P450; Calcium Channel; P-gp	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Verapamil (CP-16533-1) 是一种钙通道阻滞剂，是一种口服有效的 P-gp 抑制剂。Verapamil 抑制 CYP3A4，可用于治疗高血压、心律失常和心绞痛的研究。
TP1559L	Ziconotide Acetate (107452-89-1 free base) 醋酸齐考诺肽,Prialt,Ziconotide Acetate	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Ziconotide Acetate (107452-89-1 free base) (Prialt) 是一种镇痛剂，已用于治疗神经性和非神经性疼痛。 Ziconotide 通过与位于伤害感受通路初级传入神经元末端部分的 N 型钙通道结合起作用，因此通过有效的镇痛作用减少突触传递。
T62387	CA IX-IN-1
	CA IX-IN-1 (compound 12g) 是一种有效的、高度选择性的 hCA IX 抑制剂 (IC50: 7 nM)，表现出抗肿瘤作用。
T1824	TGR5 Receptor Agonist	GPCR19	GPCR/G Protein
	TGR5 Receptor Agonist 是一种TGR5(GPCR19)激动剂。
T2613	Almorexant 阿莫伦特,ACT 078573	OX Receptor	GPCR/G Protein; Neuroscience
	Almorexant (ACT 078573) 是一种有效的竞争性食欲素 1 受体 (OX1)/食欲素 2 受体 (OX2) 双重拮抗剂，OX1 和 OX2 的 Ki 值分别为 1.3 和 0.17 nM。
T7550	Barnidipine YM-09730-5(Free base),(4S)-2,6-二甲基-4-(间硝基苯基)-1,4-二氢吡啶-3,5-二羧酸 (3S)-1-苄基-3-吡咯烷基-甲基酯,Mepirodipine	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Barnidipine (YM-09730-5(Free base)) 是一种二氢吡啶类钙通道阻滞剂，对 CaA 受体具有选择性作用。它是一种抗高血压药物，通过减少其血管扩张作用继发的外周血管阻力起作用。
T16339	Norverapamil hydrochloride (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米	Calcium Channel; P-gp; Drug Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Norverapamil hydrochloride (D591 hydrochloride) 是 Verapamil 的 N-去甲基代谢物，是 L 型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。
T1010	Verapamil hydrochloride Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride	P450; Calcium Channel; P-gp	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Verapamil hydrochloride (Verapamil HCl) 是一种钙通道阻滞剂，是一种可口服的 P 糖蛋白 (P-gp) 抑制剂，可抑制CYP3A4，用于高血压、心律不齐和心绞痛的研究。
T1606	Fasudil HA-1077,AT877,法舒地尔	ROCK; Serine/threonin kinase; Calcium Channel; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil (HA-1077) 是一种非特异性 RhoA/ROCK 抑制剂，也是 Ca2+通道拮抗剂和血管扩张剂。它对蛋白激酶有抑制作用，ROCK1 的 Ki 值为 0.33 μM，ROCK2 和 PKA、PKC、PKG 的 IC50值分别 0.158 μM 和 4.58 μM、12.30 μM、1.650 μM。
T3060	Fasudil hydrochloride Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK; Serine/threonin kinase; Calcium Channel; HIV Protease; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil hydrochloride (HA-1077) 是一种非特异性RhoA/ROCK 抑制剂，也抑制蛋白激酶，对 ROCK1、PKA、PKC 和 MLCK 的 Ki 值分别为 0.33 μM、1.0 μM、9.3 μM 和 55 μM。
T6155	Almorexant hydrochloride ACT-078573 hydrochloride,Almorexant HCl	OX Receptor	GPCR/G Protein; Neuroscience
	Almorexant hydrochloride (ACT-078573 hydrochloride) 是一种有效的竞争性食欲素 1 受体(OX1)/食欲素 2 受体 (OX2) 双重拮抗剂，OX1 和 OX2 的 Ki 值分别为 1.3 和 0.17 nM。
T8590	4-(benzyloxy)benzene-1-sulfonamide	Others	Others
	4-(benzyloxy)benzene-1-sulfonamide 是人重组 CA-7 的抑制剂。
T67775	Enpp/Carbonic anhydrase-IN-1	PDE; Carbonic Anhydrase	Metabolism
	Enpp/Carbonic anhydrase-IN-1 (compound 1e) 是有效的 Enpp 和 carbonic anhydrase 抑制剂。Enpp/Carbonic anhydrase-IN-1抑制 NPP1、NPP2、NPP3、CA-II、CA-IX 的 IC50 值分别 1.36、1.35、3.00、0.88、1.02 µM。Enpp/Carbonic anhydrase-IN-1 选择性抑制癌细胞的增殖，对正常细胞毒性较低。
T21907	PACOCF3 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone	Phospholipase	Metabolism
	PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromethylketone) 是一种钙非依赖性的磷脂酶 A2 (phospholipase A2) 抑制剂，IC50为 3.8 μM。PACOCF3 改变肾小管细胞中的 Ca2+信号传导。
T20000	I-XW-053 4-(4,5-二苯基-1H-咪唑-2-基)苯甲酸	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	I-XW-053 是一种针对衣壳的 HIV-1 复制抑制剂，使用基于混合结构的方法以微摩尔亲和力阻断 CA N 末端结构域之间的界面（NTD-NTD 界面）。
T16500	PF-3450074 PF-74	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	PF-3450074 (PF-74)是 HIV-1 衣壳蛋白的特异性抑制剂，可广谱抑制 HIV 分离株。它在 HIV-1 感染的早期阶段起作用，通过与 CPSF6 和 NUP153 的结合直接竞争来抑制病毒复制，并阻断病毒生命周期的脱膜，组装和逆转录步骤。
T74978	DPP IV/hCA II-IN-1
	DPP IV/hCA II-IN-1 是一种有效的选择性二肽肽酶 IV (DPP IV) 和碳酸酐酶 (CA) 抑制剂，抑制 DPP IV 的 IC50值为 0.049 μM, 抑制 CA II、CA VB、CA VA、CA IX、CA I 和 CA IV 的 Ki 值分别为 0.0361、0.0428、0.0941、0.1328、0.2615 和 3.034 μM。
T60985	KCa2 channel modulator 1
	KCa2 channel modulator 1 (compound 2o) 是有效的亚型选择性的K/Ca 通道的正调节剂，其增强大鼠 KCa2.2 通道亚型的EC50值为 0.99 μM 和人KCa2.3 通道亚型的EC50值为 0.19 μM。
T83137	ALP/Carbonic anhydrase-IN-1	Carbonic Anhydrase	Metabolism
	ALP/Carbonic anhydrase-IN-1（Compound 1e）为碳酸酐酶（CA）与碱性磷酸酶（ALP）的双效抑制剂。对CA-II、CA-IX、CA-XII和ALP具有显著抑制活性，其IC50值分别为0.44 µM、1.61 µM、0.51 µM和0.107 µM。
T81865	MAPTAM
	MAPTAM是一种能够螯合细胞内Ca2+的化合物。
T72122	Carbonic anhydrase inhibitor 12	Carbonic Anhydrase	Metabolism
	碳酸酐酶抑制剂12是针对CA II具有高效抑制作用的化合物，其Kis值仅为1.72 nM，对CA I亦表现出有效抑制（Kis为271 nM）。此外，该化合物在多种肿瘤细胞系中显示出显著的抗癌活性。
T61292	CAII-IN-1
	CAII-IN-1 (compound 3n) is a thiosemicarbazide derivative that acts as a potent and selective inhibitor of carbonic anhydrase-II (CA-II), with an IC50 value of 10.3 μM for bovine CA-II. This compound (CAII-IN-1) finds utility in research pertaining to carbonic anhydrase-associated biological disorders [1].
T60986	KCa2 channel modulator 2
	KCa2 channel modulator 2 (compound 2q) 是有效的亚型选择性KCa2通道的正调节剂，对人KCa2.3 通道和大鼠 KCa2.2 通道亚型显示出相似的效力，EC50值分别为 0.6 μM 和 0.64 μM。
T61026	CaV1.3 antagonist-1
	CaV1.3 antagonist-1 是一种具有帕金森病研究潜力的环戊基衍生物。CaV1.3 antagonist-1 抑制 CaV1.3 LTCC 的效率比 CaV1.2 LTCC 高 600 多倍。CaV1.3 antagonist-1 是一种有效的、高度选择性的 CaV1.3L 型钙通道拮抗剂，IC50值为 1.7 μM。
T40895	Calmodulin antagonist-1
	Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.
T61340	CAII-IN-3
	CAII-IN-3 (compound 3h) is a thiosemicarbazone derivative known for its potent inhibition of carbonic anhydrase-II (CA-II). It exhibits an IC50 value of 13.4 μM [1].
T80449	ω-Conotoxin CVIE	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	ω-Conotoxin CVIE为电压门控钙离子通道(Cav2.2)的选择性抑制剂。
T80554	Myoregulin MLN peptide	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Myoregulin（MLN peptide）为调节蛋白家族成员，作用于肌肉性能调控，通过影响细胞内钙处理机制实现其功能。它直接与SERCA相互作用，抑制Ca2+进入肌浆网。
T75727	ω-Conotoxin GVIA TFA
	ω-Conotoxin GVIA TFA 是一种 N 型钙通道 (Ca2+channel) 抑制剂。
T80556	wt hMLN	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	wt hMLN为抑制SR Ca2+泵（SERCA）的微量蛋白，对骨骼肌钙稳态具有关键作用。
T60930	CAXII-IN-1
	CAXII-IN-1 (Compound 17) 具有抗肿瘤活性，它是 CA XII 的选择性抑制剂。CAXII-IN-1 对 hCA XII 和 hCA IX 的 Ki 值分别为 3.8 nM 和 56.0 nM。
T60515	CaMKIIα-IN-1
	CaMKIIα-IN-1 (Compound 4d) 是一种具有口服活性的 Ca 2+/钙调素依赖性蛋白激酶 II α (CaMKIIα) 抑制剂。CaMKIIα-IN-1对 CaMKIIα WT hub 的 Kd 值为 219 nM。CaMKIIα-IN-1 表现出良好的代谢稳定性。
T78413	ETZ C3-CA-DTZ
	ETZ (C3-CA-DTZ) 是一种具潜力的荧光素酶前体，能在体内经非特异性酯酶活化，促进荧光素在脑部的传输。
T63752	hCAII-IN-1
	hCAII-IN-1 (compound 7f) 是选择性的、有效的碳酸酐酶 (CA II/IX) 抑制剂，他们的 Kis 值分别为 1.2 和 113.6 nM。hCAII-IN-1 对癌症疾病表现出研究潜力。
T73030	hCAIX-IN-14
	hCAIX-IN-14 是一种有效的人类CA IX 抑制剂，Ki 值为 134.8 nM。
T63753	hCAIX-IN-3
	hCAII-IN-3 (compound 7e) 是选择性的、有效的碳酸酐酶 (CA II/IX) 抑制剂，他们的 Kis 值分别为 124.2 和 30.5 nM。hCAII-IN-1 对癌症疾病表现出研究潜力。
T79753	hCAIX/XII-IN-8	Carbonic Anhydrase	Metabolism
	hCAIX/XII-IN-8（compound 3g）是一种对人类（碳酸酐酶）CA IX和XII高效的抑制剂，Ki值分别为8.5和6.7 nM。该化合物对与肿瘤相关的膜结合异构体hCA IX和XII表现出显著的抑制作用，且相对于胞内异构体hCA I和II具有较高的选择性。
T23102	OBAA	Others	Others
	OBAA 是一种有效的磷脂酶 A2 (PLA2) 抑制剂(IC50= 70 nM)，并且在布氏锥虫中阻断 Melittin 诱导的 Ca2+流入(IC50= 0.4 μM)。
T37403	O-desmethyl Brinzolamide (hydrochloride)
	O-desmethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1,2It inhibits CAII and CAIV (IC50s = 0.136 and 165 nM, respectively).1 1.Huang, Q., Rui, E.Y., Cobbs, M., et al.Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressureJ. Med. Chem.58(6)2821-2833(2015) 2.Lo Faro, A.F., Tini, A., Gottardi, M., et al.Development and validation of a fast ultra-high-performance liquid chromatography tand...
T80170	Tamapin	Potassium Channel	Membrane transporter/Ion channel
	Tamapin为靶向小电导Ca(2+)激活的K(+) (SK)通道的毒液肽，尤以钾通道SK2为选择性阻断剂。该化合物能够抑制海马锥体神经元SK通道介导的电流，来源于印度红蝎(Mesobuthus tamulus)。
T61842	Carbonic anhydrase inhibitor 14
	Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibits CDK2 with an IC 50 of 20.3 μM. Furthermore, Carbonic anhydrase inhibitor 14 demonstrates significant antitumor activity [1].

化合物

Cat.No: T10658

Synonym: GS-6207 analog

Target: HIV Protease

Ca2+ channel agonist 1

Cat.No: T10659

Target: Calcium Channel, CDK

Cat.No: T9027

Synonym: Emavusertib

Target: IRAK, FLT

Cat.No: T5354

Synonym: CA-4948

Target: IRAK

Cav 2.2 blocker 1

Cat.No: T10690

Target: Calcium Channel

SERCA2a activator 1

Cat.No: T16873

Target: Calcium Channel

Cat.No: T12378L

Synonym: PD-1-IN-1

Target: Others

Cat.No: T7334

Synonym: 39-1B4,1-【4-(二苯甲基)-1-哌嗪基】-3,3-二苯基-1-丙酮

Target: Calcium Channel

Cat.No: T60012

Target: IRAK, MAPK, CDK

Cat.No: T20656

Synonym: NSC 135784,维拉帕米,NSC-135784,CP-16533-1,(±)-Verapamil

Target: P450, Calcium Channel, P-gp

Ziconotide Acetate (107452-89-1 free base)

Cat.No: TP1559L

Synonym: 醋酸齐考诺肽,Prialt,Ziconotide Acetate

Target: Calcium Channel

Cat.No: T62387

TGR5 Receptor Agonist

Cat.No: T1824

Target: GPCR19

Cat.No: T2613

Synonym: 阿莫伦特,ACT 078573

Target: OX Receptor

Cat.No: T7550

Synonym: YM-09730-5(Free base),(4S)-2,6-二甲基-4-(间硝基苯基)-1,4-二氢吡啶-3,5-二羧酸 (3S)-1-苄基-3-吡咯烷基-甲基酯,Mepirodipine

Target: Calcium Channel

Norverapamil hydrochloride

Cat.No: T16339

Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米

Target: Calcium Channel, P-gp, Drug Metabolite

Verapamil hydrochloride

Cat.No: T1010

Synonym: Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride

Target: P450, Calcium Channel, P-gp

Cat.No: T1606

Synonym: HA-1077,AT877,法舒地尔

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Fasudil hydrochloride

Cat.No: T3060

Synonym: Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Almorexant hydrochloride

Cat.No: T6155

Synonym: ACT-078573 hydrochloride,Almorexant HCl

Target: OX Receptor

4-(benzyloxy)benzene-1-sulfonamide

Cat.No: T8590

Target: Others

Enpp/Carbonic anhydrase-IN-1

Cat.No: T67775

Target: PDE, Carbonic Anhydrase

Cat.No: T21907

Synonym: 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone

Target: Phospholipase

Cat.No: T20000

Synonym: 4-(4,5-二苯基-1H-咪唑-2-基)苯甲酸

Target: HIV Protease

Cat.No: T16500

Synonym: PF-74

Target: HIV Protease

DPP IV/hCA II-IN-1

Cat.No: T74978

KCa2 channel modulator 1

Cat.No: T60985

ALP/Carbonic anhydrase-IN-1

Cat.No: T83137

Target: Carbonic Anhydrase

Cat.No: T81865

Carbonic anhydrase inhibitor 12

Cat.No: T72122

Target: Carbonic Anhydrase

Cat.No: T61292

KCa2 channel modulator 2

Cat.No: T60986

CaV1.3 antagonist-1

Cat.No: T61026

Calmodulin antagonist-1

Cat.No: T40895

Cat.No: T61340

ω-Conotoxin CVIE

Cat.No: T80449

Target: Calcium Channel

Cat.No: T80554

Synonym: MLN peptide

Target: Calcium Channel

ω-Conotoxin GVIA TFA

Cat.No: T75727

Cat.No: T80556

Target: Calcium Channel

Cat.No: T60930

Cat.No: T60515

Cat.No: T78413

Synonym: C3-CA-DTZ

Cat.No: T63752

Cat.No: T73030

Cat.No: T63753

Cat.No: T79753

Target: Carbonic Anhydrase

Cat.No: T23102

Target: Others

O-desmethyl Brinzolamide (hydrochloride)

Cat.No: T37403

Cat.No: T80170

Target: Potassium Channel

Carbonic anhydrase inhibitor 14

Cat.No: T61842

Cat. No.	Product Name	Target	Signaling Pathways
T10024	1-Octanol Octanol,正辛醇	Calcium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	1-Octanol (Octanol) 是一种饱和脂肪醇，是一种 T 型钙通道抑制剂，对天然 T 电流的IC50为 4 μM。它是一种具有类似柴油特性的极具吸引力的生物燃料。
T6856	Halofuginone 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110	Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Stem Cells
	Halofuginone (RU-19110) 是Febrifugine 的衍生物，是一种竞争性脯氨酰-tRNA 合成酶抑制剂。它也是肺血管扩张剂，可激活Kv 通道并阻断电压门控、受体操作和存储操作的钙离子通道。它具有抗炎、抗癌、抗疟疾和抗纤维化作用。
T3524	Halofuginone hydrobromide 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐	Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
	Halofuginone hydrobromid 是Febrifugine 的衍生物，是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂，并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。
T5782	Bevirimat YK FH312,MPC-4326,PA-457,贝韦立马	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Bevirimat (PA-457) 是一种 HIV-1 成熟抑制剂，可在病毒体成熟过程中阻断 Gag 衣壳 (CA) 前体 CA-SPI 裂解为成熟的 CA 蛋白。
T4S1419	(±)-Praeruptorin A Praeruptorin A,(±)-白花前胡甲素,白花前胡甲素,(-)-Praeruptorin A	p38 MAPK; Calcium Channel; Akt	Cytoskeletal Signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
	(±)-Praeruptorin A 是来自白花前胡的干燥根中的一种主要成分，用于研究伴有厚痰和呼吸困难的咳嗽，非天生性咳嗽和上呼吸道感染。它是顺式-内酯 (CKL) 的二酯化产物，可作为 Ca2+-反流阻滞剂，用于高血压的研究。
TN1727	Helichrysetin 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭	Apoptosis; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Helichrysetin 是从豆蔻果实中分离出的一种天然产物，是一种 DNA 结合抑制剂，可抑制原位导管癌DCIS 的形成。它抑制细胞生长，可诱导 A549 细胞凋亡。
T2S2215	Crebanine	Apoptosis; Others; Akt	Apoptosis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling
	Crebanine 是来自于韦诺萨千金藤的一种生物碱，通过抑制 MAPKs 和 Akt 信号通路表现出抗炎活性，还具有抗心律失常的作用。它可诱导人类癌细胞的 G1阻滞和凋亡。
T6S2140	β-Anhydroicaritin Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素	MMP; Others; TNF; Interleukin	Apoptosis; Immunology/Inflammation; Others; Proteases/Proteasome
	β-Anhydroicaritin 是从乳香提取的一种天然产物，具有重要的生物学和药理学作用，如抗骨质疏松症，雌激素调节和抗肿瘤特性。它改善牙周组织的降解，抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。它抑制细胞内 Ca2+的升高，并显著降低 iNOS 蛋白的表达。
T4S2326	Cornuside 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside	ERK; p38 MAPK; NF-κB; JNK	MAPK; NF-κB
	Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷，可用于炎症疾病的研究和促进血液循环。它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应，用于炎性过敏性疾病中的潜能。
TN2534	1-Hydroxy-2,3,5-trimethoxyxanthone	IκB/IKK; Calcium Channel; NOS; 5-HT Receptor; COX	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type voltage-operated Ca(2+) channels; a minor contribution to the effects of HM-1 may be related to inhibition of the protein kinase C-mediated release of intracellular Ca(2+) stores. HM-1,at the concentration of 1 ug/mL, can effectively inhibit the osteoclast differentiation in a co-c...
T75670	Lacto-N-fucopentaose II
	Lacto-N-fucopentaose II (LNFP II)作为人Lewis血型决定因子的半抗原，其单唾液神经节苷/糖脂以及唾液酰衍生物CA 19-9，都是胆胰恶性肿瘤中的分子肿瘤标记物(TM)。
T82764	Cd1a β-TRTX-cd1a,β-Theraphotoxin-cd1a
	Cd1a是从非洲蜘蛛Ceratogyrus darlingi中提取的β-毒素，具有调节钙离子通道的功能。它能够抑制人类的钙离子通道(Cav2.2)(IC50 2.6 μM)以及小鼠的钠离子通道(Nav1.7)，有望用于开发治疗外周疼痛的药物。
T75333	Quinine hemisulfate hydrate
	Quinine hemisulfate hydrate，一种从金鸡纳树皮提取的生物碱，具有抗疟疾效果。作为钾离子通道 (potassium channel) 抑制剂，它能够抑制由电压脉冲触发的MT mSlo3 (KCa5.1) 通道在+100 mV下的电流活动，其IC50值达169 μM。
T74193	(R)-IDHP
	(R)-IDHP为IDHP异构体，属于丹参代谢物。该化合物能通过抑制血管平滑肌细胞电压依赖性钙通道与受体操作钙通道的Ca2+释放和Ca2+内流，发挥血管松弛作用，适用于心脑血管疾病研究。

天然产物

Cat.No: T10024

Synonym: Octanol,正辛醇

Target: Calcium Channel, Endogenous Metabolite

Cat.No: T6856

Synonym: 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110

Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Halofuginone hydrobromide

Cat.No: T3524

Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Cat.No: T5782

Synonym: YK FH312,MPC-4326,PA-457,贝韦立马

Target: HIV Protease

(±)-Praeruptorin A

Cat.No: T4S1419

Synonym: Praeruptorin A,(±)-白花前胡甲素,白花前胡甲素,(-)-Praeruptorin A

Target: p38 MAPK, Calcium Channel, Akt

Cat.No: TN1727

Synonym: 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭

Target: Apoptosis, HIV Protease

Cat.No: T2S2215

Target: Apoptosis, Others, Akt

β-Anhydroicaritin

Cat.No: T6S2140

Synonym: Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素

Target: MMP, Others, TNF, Interleukin

Cat.No: T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

1-Hydroxy-2,3,5-trimethoxyxanthone

Cat.No: TN2534

Target: IκB/IKK, Calcium Channel, NOS, 5-HT Receptor, COX

Lacto-N-fucopentaose II

Cat.No: T75670

Cat.No: T82764

Synonym: β-TRTX-cd1a,β-Theraphotoxin-cd1a

Quinine hemisulfate hydrate

Cat.No: T75333

Cat.No: T74193

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00731	Carbonic Anhydrase 1 Protein, Human, Recombinant (His) Carbonic Anhydrase B,Carbonate Dehydratase...	Human	E. coli
	Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam...
TMPK-00283	CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) RCC,EC 4.2.1.1,CA9,P54/58N,MN,	Human	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The...
TMPK-00524	CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His) CAIX,CA9,P54/58N,RCC,G250,EC 4.2.1	Cynomolgus	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The pred...
TMPY-00519	Gastrokine 1 Protein, Human, Recombinant (His) UNQ489/PRO1005,CA11,fove...	Human	Baculovirus Insect Cells
	Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in gastric cancer. GKN1-mediated inhibition of APP processing might represent a new approach for the prevention and therapy of Alzheimer's disease (AD). In the presence of GKN2, GKN1 loses its ability to decrease cell proliferation, induce apoptosis, and inhibit epigenetic alterati...
TMPK-00828	Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc) PEMT,Episialin,Mucin1,PUM,KL-6,MUC-1,Mucin...	Human	HEK293 Cells
	MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.
TMPY-01926	S100A10 Protein, Human, Recombinant (His) ANX2L,S100 calcium binding protein A1<...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of int...
TMPH-03258	Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) Cyanamide hydratase CA1,CA-I,...	Rat	E. coli
	Reversible hydration of carbon dioxide. Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.2 kDa and the accession number is B0BNN3.
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated Polymorphic epithelial mucin,KL-6,Cancer antigen	Human	HEK293 Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1 exclusively located in the apical domain of the plasma membrane ...
TMPY-02025	CPLX2 Protein, Human, Recombinant (His) CPX-2,Hfb1,921-L,complexin 2,CPX2	Human	E. coli
	Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Complexins are unable to bind to monomeric SNARE proteins but bind with high affinity to ternary SNARE complexes and with lower affinity to target ...
TMPY-02131	Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) acid phosphatase 1, soluble,HAAP	Human	E. coli
	The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of important physiological functions, including stress resistance and synthesis of the polysaccharide capsule. ACP1/LMW-PTP is an enzyme involved in platelet-derived growth factor-induced mitogenesis and cytoskeleton rearrangement. LMW-PTP is able to specifically bind and dephosphoryl...
TMPY-04408	CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST) calcium/calmodulin-dependent protein kinas...	Human	Baculovirus Insect Cells
	Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in prostate cancer cells ability to escape apoptosis under androgen ablation and facilitate the progression of prostate cancer cells to an androgen independent state. As a multifunctional protein kinase, the loss of activity may play a critical role in initiating the changes leading to...
TMPH-03753	MYLK Protein, Human, Recombinant (His)	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPK-00383	ACE2/ACEH Protein, Human, Recombinant (His & Avi) ACE2,ACE-2,ACEH	Human	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-04346	PD-L2 Protein, Human, Recombinant (His) PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00861	IL-33 Protein, Human, Recombinant IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...	Human	E. coli
	IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His) FLK2,FLK-2,CD135,STK1,fms-related tyrosine...	Human	HEK293 Cells
	FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-01185	DR5/TRAIL R2 Protein, Human, Recombinant (His) KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His) thymic stromal lymphopoietin	Human	HEK293 Cells
	TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-06418	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) R-spondin 2,CRISTIN2	Human	HEK293 Cells
	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL	Human	E. coli
	FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant LAG-3,lymphocyte-activation gene 3,CD223	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc) WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and...	Human	HEK293 Cells
	TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-00947	VCAM-1 Protein, Human, Recombinant (hFc) INCAM-100,CD106,VCAM-	Human	HEK293 Cells
	VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-04165	FGFR3 Protein, Human, Recombinant (His) JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His) BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3	Human	HEK293 Cells
	BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-01949	CD19 Protein, Human, Recombinant (His) CD19 molecule,B4,CVID3	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-05208	PD-L1 Protein, Human, Recombinant CD274 molecule,PDCD1L1,PD-L1,PDL<...	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-03407	NQO1 Protein, Human, Recombinant (His) NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-00853	IL-1RA Protein, Human, Recombinant DIRA,IL1RA,interleukin 1 receptor antagoni...	Human	E. coli
	IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01862	IL-4 Protein, Human, Recombinant Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF	Human	E. coli
	IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-04826	LILRB5/CD85c Protein, Human, Recombinant (His) leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C	Human	HEK293 Cells
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc) leucine rich repeat containing 15,LIB	Human	HEK293 Cells
	LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-00203	LOXL2 Protein, Mouse, Recombinant (His) 1110004B06Rik,4930526G1<...	Mouse	HEK293 Cells
	Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S) Ighg1,IgG1 Fc	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-04104	LIF Protein, Human, Recombinant CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA	Human	HEK293 Cells
	LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-03290	HGF Protein, Mouse, Recombinant hepatocyte growth factor (hepapoietin A,NK1,sca...	Mouse	HEK293 Cells
	HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-02030	CD82 Protein, Human, Recombinant (His) CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) thyroid peroxidase,MSA,TPX,TDH2A	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-01894	SIGIRR Protein, Human, Recombinant (His) TIR8,single immunoglobulin and toll-interleukin 1 r...	Human	HEK293 Cells
	SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His) HHF5,CD220,insulin receptor	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E,tumor necrosis factor receptor sup...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His) W282,W264,CEA,CD66D,CGM1,MGC11987...	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-03531	PSGL-1/CD162 Protein, Human, Recombinant (His) selectin P ligand,PSGL-1,PSGL1,CD1	Human	HEK293 Cells
	PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-01147	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) RSPO,CRISTIN3,R-spondin 1	Human	HEK293 Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-02813	ErbB4 Protein, Human, Rhesus, Recombinant (His) erb-b2 receptor tyrosine kinase 4	Human,Rhesus	HEK293 Cells
	ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-01851	CD73 Protein, Human, Recombinant (His) eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CAL...	Human	HEK293 Cells
	CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
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重组蛋白

Carbonic Anhydrase 1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00731

Species: Human

Expression System: E. coli

CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00283

Species: Human

Expression System: HEK293 Cells

CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00524

Species: Cynomolgus

Expression System: HEK293 Cells

Gastrokine 1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00519

Species: Human

Expression System: Baculovirus Insect Cells

Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00828

Species: Human

Expression System: HEK293 Cells

S100A10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01926

Species: Human

Expression System: E. coli

Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03258

Species: Rat

Expression System: E. coli

Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated

Cat.No: TMPJ-00155

Species: Human

Expression System: HEK293 Cells

CPLX2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02025

Species: Human

Expression System: E. coli

Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02131

Species: Human

Expression System: E. coli

CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04408

Species: Human

Expression System: Baculovirus Insect Cells

MYLK Protein, Human, Recombinant (His)

Cat.No: TMPH-03753

Species: Human

Expression System: E. coli

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293 Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03745

Species: Human

Expression System: HEK293 Cells

ACE2/ACEH Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00383

Species: Human

Expression System: HEK293 Cells

PD-L2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04346

Species: Human

Expression System: HEK293 Cells

IL-33 Protein, Human, Recombinant

Cat.No: TMPY-00861

Species: Human

Expression System: E. coli

FLT3 Protein, Human, Recombinant (T227M, His)

Cat.No: TMPY-01247

Species: Human

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01185

Species: Human

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130S, His)

Cat.No: TMPY-05220

Species: Human

Expression System: HEK293 Cells

R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06418

Species: Human

Expression System: HEK293 Cells

FLT3 Ligand Protein, Human, Recombinant

Cat.No: TMPY-06873

Species: Human

Expression System: E. coli

LAG-3 Protein, Human, Recombinant

Cat.No: TMPY-04939

Species: Human

Expression System: HEK293 Cells

TIGIT Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04970

Species: Human

Expression System: HEK293 Cells

VCAM-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00947

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04165

Species: Human

Expression System: HEK293 Cells

BTN3A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03967

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (His)

Cat.No: TMPY-01949

Species: Human

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant

Cat.No: TMPY-05208

Species: Human

Expression System: HEK293 Cells

NQO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03407

Species: Human

Expression System: E. coli

IL-1RA Protein, Human, Recombinant

Cat.No: TMPY-00853

Species: Human

Expression System: E. coli

IL-4 Protein, Human, Recombinant

Cat.No: TMPY-01862

Species: Human

Expression System: E. coli

LILRB5/CD85c Protein, Human, Recombinant (His)

Cat.No: TMPY-04826

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04333

Species: Human

Expression System: HEK293 Cells

LOXL2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00203

Species: Mouse

Expression System: HEK293 Cells

IgG1 Fc Protein, Human, Recombinant (C103S)

Cat.No: TMPY-00820

Species: Human

Expression System: HEK293 Cells

LIF Protein, Human, Recombinant

Cat.No: TMPY-04104

Species: Human

Expression System: HEK293 Cells

HGF Protein, Mouse, Recombinant

Cat.No: TMPY-03290

Species: Mouse

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

Cat.No: TMPY-02030

Species: Human

Expression System: HEK293 Cells

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

Cat.No: TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

SIGIRR Protein, Human, Recombinant (His)

Cat.No: TMPY-01894

Species: Human

Expression System: HEK293 Cells

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

Cat.No: TMPY-01146

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01827

Species: Human

Expression System: HEK293 Cells

CEACAM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01850

Species: Human

Expression System: HEK293 Cells

PSGL-1/CD162 Protein, Human, Recombinant (His)

Cat.No: TMPY-03531

Species: Human

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01147

Species: Human

Expression System: HEK293 Cells

ErbB4 Protein, Human, Rhesus, Recombinant (His)

Cat.No: TMPY-02813

Species: Human,Rhesus

Expression System: HEK293 Cells

CD73 Protein, Human, Recombinant (His)

Cat.No: TMPY-01851

Species: Human

Expression System: HEK293 Cells

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