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Targets Recommended: Apoptosis

178

抑制剂 & 化合物

47

天然产物

2

化合物库

46

重组蛋白

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Cat. No. Product Name
L2152 靶向治疗药物库

119 compounds
119 个肿瘤靶向治疗药物,可以用于高通量和高内涵筛选;
L2151 化疗药物库

48 compounds
48 个肿瘤化疗药物,可以用于高通量和高内涵筛选;

化合物库

靶向治疗药物库
Cat.No: L2152
Compounds: 119
化疗药物库
Cat.No: L2151
Compounds: 48
Cat. No. Product Name Target Signaling Pathways
T34262 RAPTA-C

Apoptosis Apoptosis
RAPTA-C 可通过线粒体和 p53-JNK 途径诱导 EAC 细胞周期停滞和凋亡,可用于研究乳腺癌和卵巢癌。
T20656 Verapamil

NSC 135784,维拉帕米,NSC-135784,CP-16533-1,(±)-Verapamil

P450; Calcium Channel; P-gp Membrane transporter/Ion channel; Metabolism; Neuroscience
Verapamil (CP-16533-1) 是一种钙通道阻滞剂,是一种口服有效的 P-gp 抑制剂。Verapamil 抑制 CYP3A4,可用于治疗高血压、心律失常和心绞痛的研究。
TP2498 Tetrapeptide-30 Acetate

Tetrapeptide-30 Acetate(1036207-61-0 Free base)

Others Others
Tetrapeptide-30 Acetate (Tetrapeptide-30 Acetate) 是一种合成肽,含有氨基酸脯氨酸、谷氨酸和赖氨酸。它作用于皮肤的特定目标并在特定目标内起作用,以减少导致变色和肤色不均出现的因素并中断通路。
T3407L Rapastinel acetate

Rapastinel acetate (117928-94-6 Free base)

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
Rapastinel acetate 是 N-甲基-D-天冬氨酸 (NMDA) 受体的调节剂和甘氨酸位点的部分激动剂,具有长效抗抑郁作用。
TP2363L Acetyl tetrapeptide-2 Acetate

Acetyl tetrapeptide-2 Acetate(757942-88-4 Free base)

Others Others
Acetyl tetrapeptide-2 Acetate 常用作皮肤调理剂。 Acetyl tetrapeptide-2 Acetate 是通过补偿皮肤中的激素损失来完成的,尤其是胶原蛋白,为皮肤提供了一些丰满的效果。
T38852L TRAP-6 amide acetate

Protease-activated Receptor GPCR/G Protein
TRAP-6 amide acetate 是一种 PAR-1 凝血酶受体激动剂肽。
T7820 Raphin1

Phosphatase Metabolism
Raphin1 是一种口服具有活力的、可透过血脑屏障的、选择性调节性磷酸酶 PPP1R15B(R15B) 抑制剂。它与 R15B-PP1c 全磷酸酶强烈结合 (Kd=33 nM),与 R15A-PP1c 相比,结合 R15B-PP1c 约为其 30 倍的选择性。它可减少蛋白质错误折叠疾病的小鼠模型中的生物和分子缺陷。
T38563 Raptinal

Caspase Apoptosis; Proteases/Proteasome
Raptinal 直接激活 caspase-3 并在多种细胞系中启动内在的 caspase 依赖性细胞凋亡途径。
T125901 14-Epiandrographolide

14-Epiandrographolide 是从穿心莲地上部分提取到的化合物,可诱导细胞分化,可用于研究多发性硬化症。
TP2313 Acetyl Tetrapeptide-5 acetate

Acetyl Tetrapeptide-5 acetate(820959-17-9 free base)

Others Others
Acetyl Tetrapeptide-5 acetate(820959-17-9 free base) 有助于减少眼部浮肿,改善皮肤弹性以及整体光滑度。
T1010 Verapamil hydrochloride

Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride

P450; Calcium Channel; P-gp Membrane transporter/Ion channel; Metabolism; Neuroscience
Verapamil hydrochloride (Verapamil HCl) 是一种钙通道阻滞剂,是一种可口服的 P 糖蛋白 (P-gp) 抑制剂,可抑制CYP3A4,用于高血压、心律不齐和心绞痛的研究。
T6892 Niraparib tosylate

尼拉帕利,MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate,尼拉帕尼对苯甲磺酸盐

Apoptosis; PARP Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
Niraparib tosylate (MK-4827(tosylate)) 是一种高效的,具有生物口服利用度的PARP1和PARP2抑制剂,IC50分别为 3.8 和 2.1 nM。它抑制 DNA 损伤修复,诱导凋亡并具有抗肿瘤活性。
T16339 Norverapamil hydrochloride

(±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米

Calcium Channel; P-gp; Drug Metabolite Membrane transporter/Ion channel; Metabolism; Neuroscience
Norverapamil hydrochloride (D591 hydrochloride) 是 Verapamil 的 N-去甲基代谢物,是 L 型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。
T7013 Vorapaxar

SCH 530348,MK-5348,沃拉帕沙

Protease-activated Receptor GPCR/G Protein
Vorapaxar (MK-5348) 是抗血小板药物,是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂,Ki 值为 8.1 nM。它靠剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集。
T2499 Torcetrapib

CP-529414,托彻普

CETP Metabolism
是胆固醇酯转移蛋白 (CETP) 选择性抑制剂。根据人血浆的抑制曲线,Torcetrapib (CP-529414) 对CETP 的最有效浓度为 37 nM。
TP2365L Acetyl tetrapeptide-9 Acetate

Acetyl tetrapeptide-9 Acetate(928006-50-2 Free base)

Others Others
Acetyl tetrapeptide-9 Acetate 在刺激基底膜多糖(lumican)和胶原蛋白 I 的合成中发挥作用。
T11221 ERAP1-IN-1

Others Others
ERAP1-in-1 是一种内质网氨基肽酶 1 (ERAP1) 抑制剂,能竞争性地抑制 ERAP1 对代表性生物底物九聚物肽的作用。
T3353 Niraparib hydrochloride

尼拉帕利盐酸盐,MK-4827 hydrochloride,MK-4827 (hydrochloride)

Apoptosis; Others; PARP Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
Niraparib hydrochloride (MK-4827 hydrochloride) 是一种具有口服活性的PARP1和PARP2抑制剂,IC50值分别为 3.8 nM 和 2.1 nM。它抑制 DNA 损伤修复,诱导凋亡并具有抗肿瘤活性。
T1595 Nevirapine

NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP

HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Nevirapine (NVP) 是一种 HIV-1逆转录酶非核苷抑制剂,Ki 值为 270 μM,可用于研究 HIV/AIDS。
T7744 Piperaquine tetraphosphate tetrahydrate

4,4'-(1,3-丙烷双-4,1-哌嗪基)双(7-氯喹啉)磷酸盐水合物,四磷酸哌喹四水合物

Parasite Microbiology/Virology
Piperaquine tetraphosphate tetrahydrate 是一种双喹啉抗寄生虫剂,可与青蒿素联用研究抗疟。
T7221 Satraplatin

BMS182751,JM216,顺式-二氯-反式-二乙酸-氨-环己胺合铂,BMY45594

DNA Alkylator/Crosslinker; DNA Alkylation DNA Damage/DNA Repair
Satraplatin (BMS182751) 是一种烷化剂 ,是一种口服的抗肿瘤铂 (IV) 复合物,具有广泛的抗肿瘤效果。
T10820L1 Ciraparantag acetate

Ciraparantag acetate(1438492-26-2 Free base)

Others Others
Ciraparantag acetate 是一种抗凝逆转剂,是一种小分子,专门设计用于通过电荷-电荷相互作用与普通肝素和低分子量肝素非共价结合。它显示出与直接口服抗凝剂 (DOAC) 相似的结合特性。
T12064 Niraparib (R-enantiomer)

MK 4827 (R-enantiomer),Niraparib R-enantiomer

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Niraparib R-enantiomer (MK 4827 R-enantiomer) 是一种 PARP1抑制剂,IC50为 2.4 nM。
T68165 Trapencaine

Trapencaine 是一种新合成的氨基甲酸型局部麻醉剂,诱导的肥大细胞膜上钠通道的构象变化。
T9497 Niraparib tosylate monohyrate

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Niraparib tosylate monohyrate 也称为 MK-4827,是一种聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂,具有潜在的抗肿瘤活性。 MK4827 抑制 PARP 活性,增强 DNA 链断裂的积累,促进基因组不稳定性和细胞凋亡。 PARP 蛋白家族通过碱基切除修复 (BER) 途径检测和修复单链 DNA 断裂。
T0165 Urapidil

Mediatensyl,乌拉地尔,Ebrantil,Eupressyl

5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Urapidil (Ebrantil) 是交感神经抗高血压药物,可作为 5-HT1A 受体激动剂和 α1-肾上腺素受体拮抗剂。
TP2364L Acetyl tetrapeptide-3 Acetate

Acetyl tetrapeptide-3 Acetate(827306-88-7 Free base)

Others Others
Acetyl tetrapeptide-3 Acetate 是一种仿生肽。
T5819 Rapastinel Trifluoroacetate

Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) 是一种 NMDA 受体调节剂,具有甘氨酸位点部分激动剂性质,有研究抑郁症的潜力。
TP2497 Myristoyl Tetrapeptide-12 Acetate

醋酸肉蔻酰四胜肽-12,Myristoyl Tetrapeptide-12 Acetate(959610-24-3 Free base)

Others Others
Myristoyl Tetrapeptide-12 Acetate (Myristoyl Tetrapeptide-12 Acetate (959610-24-3 Free base)) 是肉豆蔻酸和 Tetrapeptide-12 的反应产物,是一种刺激头发和睫毛生长并增强睫毛和/或眉毛外观的肽。 Myristoyl tetrapeptide-12 可以增加角质形成细胞的增殖,改善外观、紧致弹性和皮肤厚度。
T8519 Raphin1 acetate

Phosphatase Metabolism
Raphin1 acetate 是具有口服活性的、可透过血脑屏障的、选择性调节性磷酸酶PPP1R15B 抑制剂。它与 R15B-PP1c 全磷酸酶强烈结合 (Kd=33 nM),与 R15A-PP1c 相比,结合 R15B-PP1c 约为其 30 倍的选择性。它可减少蛋白质错误折叠疾病的小鼠模型中的生物和分子缺陷。
TP1042 Palmitoyl Tetrapeptide-3

Rigin,棕榈酰四肽-7/棕榈酰四肽-3

Others Others
Palmitoyl Tetrapeptide-3 (Rigin) 是一种具有刺激吞噬活性的合成多肽,对应人免疫球蛋白重链的第 341-344 氨基酸序列。
T0293 Metyrapone

美替拉酮,甲吡酮,NSC-25265,Su-4885

Others; P450; Dehydrogenase; Autophagy Autophagy; Metabolism; Others
Metyrapone (NSC-25265) 是 STEROID 11-BETA-MONOOXYGENASE 酶抑制剂。 它被用作库欣综合征诊断中下丘脑-垂体反馈机制的测试。
T11824LL Lanraplenib

GS-9876

Syk Angiogenesis; Tyrosine Kinase/Adaptors
Lanraplenib (GS-9876) 是高效的、选择性的、口服具有活力的 SYK 抑制剂 (IC50=9.5 nM) ,能够用于炎症性疾病的研究。它通过糖蛋白 VI (GPVI) 受体抑制血小板中的 SYK 活性,而不会延长猴子或人类的出血时间 (BT)。
T0088 Urapidil hydrochloride

Urapidil HCl,盐酸乌拉地尔

5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Urapidil hydrochloride (Urapidil HCl) 是α1-肾上腺素受体拮抗剂和5-HT1A 受体激动剂。
T69140 Burapitant

SSR 240600

Neurokinin receptor GPCR/G Protein; Neuroscience
Burapitant(SSR 240600)是一种新型非肽速激肽神经激肽 1 (NK) 受体拮抗剂,具有抗焦炉和抗抑郁活性。
T6262 Evacetrapib

LY2484595

CETP Metabolism
Evacetrapib (LY2484595) 是 CETP 的选择性抑制剂,在人血浆中,抑制人重组 CETP 蛋白 (IC50:5.5 nM) 和 CETP (IC50:36 nM) 活性。
T6048 Dalcetrapib

JTT-705,达塞曲匹,RO4607381

CETP Metabolism
Dalcetrapib (RO4607381) 是rhCETP 抑制剂(IC50:0.2 μM),具有增加血浆中HDL 胆固醇含量的作用。
TP2489 Tetrapeptide-21 Acetate

Tetrapeptide-21 Acetate(960608-17-7 Free base)

Others Others
Tetrapeptide-21 Acetate 是一种新型生物活性纯四肽,具有基于皮肤自身结构的抗衰老特性,可用于护肤配方。
T31204 Darapladib-impurity

Others Others
Darapladib-impurity 是 Darapladib 的杂质。Darapladib 对脂蛋白相关磷脂酶 A2 (Lp-PLA2)有抑制作用。
T4434 Tirapazamine

Tirazone,Win59075,SR4233,替拉扎明,SR259075

Others Others
Tirapazamine (Win59075) 是抗癌剂,对实体瘤中的缺氧细胞具有选择性细胞毒性,促使 DNA 中的单链和双链断裂,碱基损伤和细胞死亡。
T16697 Pyronaridine tetraphosphate

Topoisomerase DNA Damage/DNA Repair
Pyronaridine tetraphosphate 是一种具有口服活性的、含甘露醇的DNA 拓扑异构酶 2 的抑制剂和红细胞裂殖杀灭剂,具有抗疟活性和抗肿瘤活性。Pyronaridine tetraphosphate 可治疗 P. falciparum 和 Echinococcus granulosus感染,可减轻埃博拉病毒传播。
T3098 Vorapaxar sulfate

SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙

Protease-activated Receptor GPCR/G Protein
Vorapaxar sulfate (Zontivity) 是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂,Ki 值为 8.1 nM。它剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集,是抗血小板药物。
T1928 Anacetrapib

安塞曲匹,MK-0859

CETP Metabolism
Anacetrapib (MK-0859) 是 CETP 的抑制剂,能够抑制 rhCETP (IC50:7.9±2.5 nM) 和 C13S CETP 突变型 (IC50:11.8±1.9 nM) 的活性。
T0080 Trapidil

唑嘧胺,乐可安,Rocornal,Trapymine,Avantrin,Trapymin,AR-12008

PDGFR; PDE Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
Trapidil (Avantrin) 是一种抗血小板药物,是一种血管扩张剂,有特异性血小板衍生生长因子。
T28225 Obicetrapib

TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995

CETP Metabolism
Obicetrapib (AMG-899) 是胆固醇酯转移蛋白的抑制剂。
TQ0292 Grapiprant

AAT-007,RQ-00000007,CJ-023423

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Grapiprant (AAT-007) 是一种选择性EP4 受体拮抗剂,生理配体为前列腺素 E2(PGE2),有用于骨关节炎疼痛和炎症的研究潜力。它取代 [3H]-PGE2(1 nM) 与狗的重组EP4 受体结合,IC50为 35 nM,Ki 为 24 nM。
T7625 TRAP-6

PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)

Protease-activated Receptor GPCR/G Protein
TRAP-6 (Thrombin Receptor Activator Peptide 6) 是一种多肽片段,是选择性的蛋白酶激活受体 1 (PAR1) 激动剂,通过凝血酶受体激活人血小板。
T6109 Darapladib

达拉地,SB-480848

Phospholipase Metabolism
Darapladib (SB-480848) 是脂蛋白相关磷脂酶A2 (Lp-PLA2) 抑制剂,IC50=0.25 nM。
T20494L Acetyl tetrapeptide-15 Acetate

Skinasensyl Acetate,Acetyl tetrapeptide-15 Acetate (928007-64-1 Free base)

Acetyl tetrapeptide-15 Acetate (Skinasensyl Acetate) 是一种用于敏感皮肤的化妆品中的合成肽,是 endomorphin-2 衍生物, 通过内啡肽样通路扩大 μ-阿片受体中的神经元兴奋性阈值范围,可用于研究由皮肤高反应性产生的炎症性和神经性疼痛。
T3231 Niraparib

尼拉帕尼,MK-4827

Apoptosis; Others; PARP Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
Niraparib (MK-4827) 是一种 PARP 抑制剂,可以抑制 PARP1 和 PARP2 (IC50=3.8/2.1 nM),具有选择性。Niraparib 具有抗肿瘤活性,可以抑制 DNA 损伤修复、诱导细胞凋亡。

化合物

RAPTA-C
Cat.No: T34262
Synonym:
Target: Apoptosis
Verapamil
Cat.No: T20656
Synonym: NSC 135784,维拉帕米,NSC-135784,CP-16533-1,(±)-Verapamil
Target: P450, Calcium Channel, P-gp
Tetrapeptide-30 Acetate
Cat.No: TP2498
Synonym: Tetrapeptide-30 Acetate(1036207-61-0 Free base)
Target: Others
Rapastinel acetate
Cat.No: T3407L
Synonym: Rapastinel acetate (117928-94-6 Free base)
Target: NMDAR, iGluR
Acetyl tetrapeptide-2 Acetate
Cat.No: TP2363L
Synonym: Acetyl tetrapeptide-2 Acetate(757942-88-4 Free base)
Target: Others
TRAP-6 amide acetate
Cat.No: T38852L
Synonym:
Target: Protease-activated Receptor
Raphin1
Cat.No: T7820
Synonym:
Target: Phosphatase
Raptinal
Cat.No: T38563
Synonym:
Target: Caspase
14-Epiandrographolide
Cat.No: T125901
Synonym:
Target:
Acetyl Tetrapeptide-5 acetate
Cat.No: TP2313
Synonym: Acetyl Tetrapeptide-5 acetate(820959-17-9 free base)
Target: Others
Verapamil hydrochloride
Cat.No: T1010
Synonym: Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride
Target: P450, Calcium Channel, P-gp
Niraparib tosylate
Cat.No: T6892
Synonym: 尼拉帕利,MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate,尼拉帕尼对苯甲磺酸盐
Target: Apoptosis, PARP
Norverapamil hydrochloride
Cat.No: T16339
Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米
Target: Calcium Channel, P-gp, Drug Metabolite
Vorapaxar
Cat.No: T7013
Synonym: SCH 530348,MK-5348,沃拉帕沙
Target: Protease-activated Receptor
Torcetrapib
Cat.No: T2499
Synonym: CP-529414,托彻普
Target: CETP
Acetyl tetrapeptide-9 Acetate
Cat.No: TP2365L
Synonym: Acetyl tetrapeptide-9 Acetate(928006-50-2 Free base)
Target: Others
ERAP1-IN-1
Cat.No: T11221
Synonym:
Target: Others
Niraparib hydrochloride
Cat.No: T3353
Synonym: 尼拉帕利盐酸盐,MK-4827 hydrochloride,MK-4827 (hydrochloride)
Target: Apoptosis, Others, PARP
Nevirapine
Cat.No: T1595
Synonym: NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP
Target: HIV Protease, Reverse Transcriptase
Piperaquine tetraphosphate tetrahydrate
Cat.No: T7744
Synonym: 4,4'-(1,3-丙烷双-4,1-哌嗪基)双(7-氯喹啉)磷酸盐水合物,四磷酸哌喹四水合物
Target: Parasite
Satraplatin
Cat.No: T7221
Synonym: BMS182751,JM216,顺式-二氯-反式-二乙酸-氨-环己胺合铂,BMY45594
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Ciraparantag acetate
Cat.No: T10820L1
Synonym: Ciraparantag acetate(1438492-26-2 Free base)
Target: Others
Niraparib (R-enantiomer)
Cat.No: T12064
Synonym: MK 4827 (R-enantiomer),Niraparib R-enantiomer
Target: PARP
Trapencaine
Cat.No: T68165
Synonym:
Target:
Niraparib tosylate monohyrate
Cat.No: T9497
Synonym:
Target: PARP
Urapidil
Cat.No: T0165
Synonym: Mediatensyl,乌拉地尔,Ebrantil,Eupressyl
Target: 5-HT Receptor, Adrenergic Receptor
Acetyl tetrapeptide-3 Acetate
Cat.No: TP2364L
Synonym: Acetyl tetrapeptide-3 Acetate(827306-88-7 Free base)
Target: Others
Rapastinel Trifluoroacetate
Cat.No: T5819
Synonym: Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate
Target: NMDAR, iGluR
Myristoyl Tetrapeptide-12 Acetate
Cat.No: TP2497
Synonym: 醋酸肉蔻酰四胜肽-12,Myristoyl Tetrapeptide-12 Acetate(959610-24-3 Free base)
Target: Others
Raphin1 acetate
Cat.No: T8519
Synonym:
Target: Phosphatase
Palmitoyl Tetrapeptide-3
Cat.No: TP1042
Synonym: Rigin,棕榈酰四肽-7/棕榈酰四肽-3
Target: Others
Metyrapone
Cat.No: T0293
Synonym: 美替拉酮,甲吡酮,NSC-25265,Su-4885
Target: Others, P450, Dehydrogenase, Autophagy
Lanraplenib
Cat.No: T11824LL
Synonym: GS-9876
Target: Syk
Urapidil hydrochloride
Cat.No: T0088
Synonym: Urapidil HCl,盐酸乌拉地尔
Target: 5-HT Receptor, Adrenergic Receptor
Burapitant
Cat.No: T69140
Synonym: SSR 240600
Target: Neurokinin receptor
Evacetrapib
Cat.No: T6262
Synonym: LY2484595
Target: CETP
Dalcetrapib
Cat.No: T6048
Synonym: JTT-705,达塞曲匹,RO4607381
Target: CETP
Tetrapeptide-21 Acetate
Cat.No: TP2489
Synonym: Tetrapeptide-21 Acetate(960608-17-7 Free base)
Target: Others
Darapladib-impurity
Cat.No: T31204
Synonym:
Target: Others
Tirapazamine
Cat.No: T4434
Synonym: Tirazone,Win59075,SR4233,替拉扎明,SR259075
Target: Others
Pyronaridine tetraphosphate
Cat.No: T16697
Synonym:
Target: Topoisomerase
Vorapaxar sulfate
Cat.No: T3098
Synonym: SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙
Target: Protease-activated Receptor
Anacetrapib
Cat.No: T1928
Synonym: 安塞曲匹,MK-0859
Target: CETP
Trapidil
Cat.No: T0080
Synonym: 唑嘧胺,乐可安,Rocornal,Trapymine,Avantrin,Trapymin,AR-12008
Target: PDGFR, PDE
Obicetrapib
Cat.No: T28225
Synonym: TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995
Target: CETP
Grapiprant
Cat.No: TQ0292
Synonym: AAT-007,RQ-00000007,CJ-023423
Target: Prostaglandin Receptor
TRAP-6
Cat.No: T7625
Synonym: PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)
Target: Protease-activated Receptor
Darapladib
Cat.No: T6109
Synonym: 达拉地,SB-480848
Target: Phospholipase
Acetyl tetrapeptide-15 Acetate
Cat.No: T20494L
Synonym: Skinasensyl Acetate,Acetyl tetrapeptide-15 Acetate (928007-64-1 Free base)
Target:
Niraparib
Cat.No: T3231
Synonym: 尼拉帕尼,MK-4827
Target: Apoptosis, Others, PARP
Cat. No. Product Name Target Signaling Pathways
TL0016 Sulforaphene

油菜

Apoptosis; ERK; EGFR; NF-κB Angiogenesis; Apoptosis; JAK/STAT signaling; MAPK; NF-κB; Tyrosine Kinase/Adaptors
Sulforaphene 是从萝卜种子中分离出来的天然产物,对鹿茸幼苗的 ED50 约为 2 x 10 -4 M。它通过抑制 EGFR、p-ERK1/2、NF-κB 和其他信号促进癌细胞凋亡并抑制迁移。
TN1933 Mitraphylline

帽柱木菲碱,帽柱叶碱

IL Receptor; TNF; NF-κB Apoptosis; Immunology/Inflammation; NF-κB
Mitraphylline 是一种绒毛钩藤中主要的五环吲哚类生物碱,可阻碍脂多糖介导的原代人中性粒细胞活化。
T1537 Rapamycin

Sirolimus,AY 22989,雷帕霉素,NSC-2260804

Others; Endogenous Metabolite; Antibiotic; mTOR; Autophagy; Antifungal Autophagy; Metabolism; Microbiology/Virology; Others; PI3K/Akt/mTOR signaling
Rapamycin (AY 22989) 属于大环内酯类天然产物,是一种 mTOR 抑制剂,具有特异性(HEK293 细胞:IC50=0.1 nM)。Rapamycin 具有免疫抑制活性,并能诱导自噬。
TQ0212 Glucoraphanin

Antioxidant; Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
Glucoraphanin 是一种硫代葡萄糖苷,存在于十字花科蔬菜中,是 Nrf2 诱导剂 sulforaphane 的前体,sulforaphane 有抗氧化、抗炎、抗癌作用。
TQ0207 Sulforaphane

萝卜硫素

Apoptosis; Nrf2; HDAC Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation
Sulforaphane 是存在于多种蔬菜中的一种天然异硫氰酸酯。它可以激活Nrf2,并通过 AMPK 依赖性信号传导抑制高糖诱导的胰腺癌。它增加肿瘤抑制蛋白的转录并抑制组蛋白脱乙酰酶的活性,具有抗癌和抗炎活性。
TQ0185 14-Deoxy-11,12-didehydroandrographolide

AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide

NF-κB NF-κB
14-Deoxy-11,12-didehydroandrographolide (AP10) 是一种 Andrographolide 的类似物,能够抑制 NF-κB 活性。
T2S0257 Dehydroandrographolide succinate

Others; Influenza Virus Microbiology/Virology; Others
Dehydroandrographolide succinate 是从中药穿心莲中提取的一种天然产物,具有免疫刺激、抗感染和抗炎作用,有潜力研究病毒性肺炎和病毒性上呼吸道感染。
TN4893 Rapanone

拉帕酮,2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone,2,5-Dihydroxy-3-tridecylcyclohexa-2,5-diene-1,4-dione,酸藤子醌

Apoptosis; Phospholipase; Antibacterial; Parasite Apoptosis; Metabolism; Microbiology/Virology
Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) 是一种具有广泛生物活性的天然苯醌,如抗肿瘤、抗氧化、抗炎、抗菌和抗寄生虫活性。它还是选择性人滑膜 PLA2抑制剂,IC50值为 2.6 μM。
T8281 (R)-Sulforaphane

L-Sulforaphane,(R)-1-异硫氰酰-4-(甲基亚磺酰)丁烷

Nrf2 Immunology/Inflammation
(R)-Sulforaphane (L-Sulforaphane) 是高效的Keap1/Nrf2/ARE 途径诱导剂。与 S-异构体相比,它对大鼠肝脏和肺部的致癌解毒酶系统的诱导能力更强。
T3884 Neoandrographolide

Neoandrographiside,新穿心莲内酯

NOS; COX Immunology/Inflammation; Neuroscience
Neoandrographolide (Neoandrographiside) 是一种二萜类化合物,从穿心莲中分离得到。
T6520 Grape Seed Extract

Grape Seed P.E.,葡萄籽提取物

Apoptosis; Others Apoptosis; Others
Grape Seed Extract (Grape Seed P.E.) 是葡萄植物 Vitis vinifera 的种子分泌物,能诱导人类结肠直肠癌细胞凋亡,具有抗炎和抗增殖作用。它对脂肪代谢酶、胰脂肪酶和脂蛋白脂肪酶有抑制作用。
T4115 Auraptene

橙皮油内酯,7-geranyloxycoumarin,橙皮油素

MMP; BACE Neuroscience; Proteases/Proteasome
Auraptene 是一种丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子,包括 IL-6,IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5)的分泌。
T8288 14-Deoxyandrographolide

去氧穿心莲内酯,14-去氧穿心莲内酯

Apoptosis; Others Apoptosis; Others
14-Deoxyandrographolide 是穿心莲中的一种天然产物,是一种钙通道阻断剂,具有保肝功效。它通过诱导 TNFRSF1A 的释放,使肝细胞对 TNF-α 介导的凋亡脱敏。
T9218 Andrograpanin

19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元

p38 MAPK MAPK
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) 是来自穿心莲的一种天然产物,具有抗炎和抗感染活性。
T37009 Oxychlororaphine

吩嗪-1-甲酰胺,phenazine-1-carboxamide

Antibacterial Microbiology/Virology
Oxychlororaphine (phenazine-1-carboxamide) 强烈抑制 Streptomyces sp. 411 的生长。
T2898 Andrographolide

Andrographis,穿心莲内酯

SARS-CoV; Influenza Virus; NF-κB; Autophagy Autophagy; Microbiology/Virology; NF-κB
Andrographolide (Andrographis) 是 NF-κB 的不可逆拮抗剂,具有抗病毒、抗炎和抗血小板聚集活性和潜在的抗肿瘤作用。
T3667 Kalii Dehydrographolidi Succinas

Ddhads,穿琥宁,Dehydroandrographolide Succinate Potasium Salt

Others Others
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) 从中药穿心莲中提取得到,具有免疫刺激、抗感染和抗炎作用,对病毒性肺炎和病毒性上呼吸道感染具有潜在的研究价值。
TQ0218 Deoxyandrographolide

去氧穿心莲内酯,14-deoxyandrographolide

IL Receptor; TNF Apoptosis; Immunology/Inflammation
Deoxyandrographolide (14-deoxyandrographolide) 抑制 LPS 诱导的 iNOS mRNA 水平升高以及促炎症介质 TNF-α 和 IL-6 的产生。它增强 NGF 诱导的神经突起生长。
TN3530 Borapetoside B

Others Others
Borapetoside B是一种天然产物,属于防己科青牛胆属,其产品编号为 TN3530,CAS号为 104901-05-5。Borapetoside B可用作对照参考。
T72580 Isoandrographolide

Isoandrographolide 具有诱导细胞分化和保肝活性。Isoandrographolide 可抑制 NLRP3炎症小体激活并减轻小鼠矽肺。
TN6599 Andrographidine A

Andrographidine A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6599,CAS号为 113963-37-4。
TN2623 14-Deoxy-17-hydroxyandrographolide

Antifection Microbiology/Virology
14-Deoxy-17-hydroxyandrographolide是一种天然产物,属于爵床科穿心莲属,其产品编号为 TN2623,CAS号为 869384-82-7。14-Deoxy-17-hydroxyandrographolide可用作对照参考。
TN4895 Rauvotetraphylline A

Others Others
Rauvotetraphylline A is a natural product from Rauvolfia tetraphylla.
T2738 Dehydroandrographolide

NOS; Influenza Virus Immunology/Inflammation; Microbiology/Virology
Dehydroandrographolide 是从草药穿心莲中提取的一种天然产物。它通过使 iNOS 失活来降低 LPS 诱导的急性肺损伤中的氧化应激,有抗感染活性。
T13582 Bisandrographolide C

Others Others
Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury.
TN4311 Isomitraphylline

Others Others
Isomitraphylline and pteropodine are the most suitable for standardization of medical cat's claw preparations. Isomitraphylline can inhibit proliferation of acute lymphoblastic leukaemia cells.
T25305 Demethoxyrapamycin

AY 24668,AY24668,AY-24668

Demethoxyrapamycin is a new antifungal antibiotic agent which is co-produced with rapamycin by Streptomyces hygroscopicus.
TN3329 9-Oxoageraphorone

Others Others
9-Oxoageraphorone has strong acaricidal activity against P. cuniculi in vitro, it also exhibits high insecticidal effects.
TN5585 14-Deoxy-11-hydroxyandrographolide

14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.
TN6038 1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine

1,2-Methylenedioxy-3,10,11-trimethoxyaporphine exerts moderate vessel-relaxing activities with the IC 50 value from 16.50 to 32.81 microM at the test concentrations.
TN2622 14-Deoxy-11,12-didehydroandrographiside

Others Others
14-Deoxy-11,12-didehydroandrographiside是一种天然产物,属于爵床科穿心莲属,其产品编号为 TN2622,CAS号为 141973-41-3。14-Deoxy-11,12-didehydroandrographiside可用作对照参考。
TN4896 Rauvotetraphylline B

Others Others
Rauvotetraphylline B is a natural product from Rauvolfia tetraphylla.
TN3531 Borapetoside D

Others Others
Borapetoside D是一种天然产物,属于防己科青牛胆属,其产品编号为 TN3531,CAS号为 151200-48-5。Borapetoside D可用作对照参考。
TN3412 Andrographiside

Others Others
Andrographiside shows protective effects on hepatotoxicity induced in mice by carbon tetrachloride or tert-butylhydroperoxide (tBHP) intoxication, the effects could be due to its glucoside groups which may act as strong antioxidants.
TN3533 Borapetoside F

Others Others
Borapetoside F是一种天然产物,属于防己科青牛胆属,其产品编号为 TN3533,CAS号为 151200-50-9。Borapetoside F可用作对照参考。
TN3411 Andrographidine C

Others Others
Andrographidine C是一种天然产物,属于爵床科穿心莲属,其产品编号为 TN3411,CAS号为 113963-39-6。Andrographidine C可用作对照参考。
TN3518 Bisandrographolide A

Others Others
Bisandrographolide A activates TRPV4 channels, could play a role in some of the effects of Andrographis extract described in traditional medicine.
TN2463 14-Deoxy-11-oxoandrographolide

Others Others
14-Deoxy-11-oxoandrographolide is a natural product from Andrographis paniculata
TN6029 Rauvotetraphylline E

Rauvotetraphylline E is a natural product from Rauvolfia tetraphylla.
TN4897 Rauvotetraphylline C

Others Others
Rauvotetraphylline C is a natural product from Rauvolfia tetraphylla.
TN3795 Dehydroborapetoside B

Others Others
Dehydroborapetoside B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3795,CAS号为 1221178-16-0。
TN5636 Caraphenol A

Caraphenol A是一种天然产物,属于豆科锦鸡儿属,其产品编号为 TN5636,CAS号为 354553-35-8。Caraphenol A可用作对照参考。
TN5586 14-Deoxy-12-hydroxyandrographolide

14-Deoxy-12-hydroxyandrographolide是一种天然产物,属于爵床科穿心莲属,其产品编号为 TN5586,CAS号为 219721-33-2。14-Deoxy-12-hydroxyandrographolide可用作对照参考。
TN3532 Borapetoside E

Others Others
Borapetoside E has anti-hyperglycemic activity, it can significantly reduce serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice.
TN4269 Isocarapanaubine

Others Others
Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica.
TN1415 Auraptenol

酸橙素烯醇

5-HT Receptor GPCR/G Protein; Neuroscience
Auraptenol possesses robust antidepressant-like efficacy in mice.
TN5336 9-Oxo-10,11-dehydroageraphorone

4,7(11)-Cadinadiene-3,8-dione,DTD,7,11-Dehydro-8-oxoageraphorone,泽兰二酮

9-Oxo-10,11-dehydroageraphorone has acaricidal activity. It induces hepatotoxicity and cholestasis in rats. 9-Oxo-10,11-dehydroageraphorone also effectively inhibits the proliferation of HeLa cells by arresting the cell cycle transition from S to G2/M pha

天然产物

Sulforaphene
Cat.No: TL0016
Synonym: 油菜
Target: Apoptosis, ERK, EGFR, NF-κB
Mitraphylline
Cat.No: TN1933
Synonym: 帽柱木菲碱,帽柱叶碱
Target: IL Receptor, TNF, NF-κB
Rapamycin
Cat.No: T1537
Synonym: Sirolimus,AY 22989,雷帕霉素,NSC-2260804
Target: Others, Endogenous Metabolite, Antibiotic, mTOR, Autophagy, Antifungal
Glucoraphanin
Cat.No: TQ0212
Synonym:
Target: Antioxidant, Reactive Oxygen Species
Sulforaphane
Cat.No: TQ0207
Synonym: 萝卜硫素
Target: Apoptosis, Nrf2, HDAC
14-Deoxy-11,12-didehydroandrographolide
Cat.No: TQ0185
Synonym: AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide
Target: NF-κB
Dehydroandrographolide succinate
Cat.No: T2S0257
Synonym:
Target: Others, Influenza Virus
Rapanone
Cat.No: TN4893
Synonym: 拉帕酮,2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone,2,5-Dihydroxy-3-tridecylcyclohexa-2,5-diene-1,4-dione,酸藤子醌
Target: Apoptosis, Phospholipase, Antibacterial, Parasite
(R)-Sulforaphane
Cat.No: T8281
Synonym: L-Sulforaphane,(R)-1-异硫氰酰-4-(甲基亚磺酰)丁烷
Target: Nrf2
Neoandrographolide
Cat.No: T3884
Synonym: Neoandrographiside,新穿心莲内酯
Target: NOS, COX
Grape Seed Extract
Cat.No: T6520
Synonym: Grape Seed P.E.,葡萄籽提取物
Target: Apoptosis, Others
Auraptene
Cat.No: T4115
Synonym: 橙皮油内酯,7-geranyloxycoumarin,橙皮油素
Target: MMP, BACE
14-Deoxyandrographolide
Cat.No: T8288
Synonym: 去氧穿心莲内酯,14-去氧穿心莲内酯
Target: Apoptosis, Others
Andrograpanin
Cat.No: T9218
Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元
Target: p38 MAPK
Oxychlororaphine
Cat.No: T37009
Synonym: 吩嗪-1-甲酰胺,phenazine-1-carboxamide
Target: Antibacterial
Andrographolide
Cat.No: T2898
Synonym: Andrographis,穿心莲内酯
Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy
Kalii Dehydrographolidi Succinas
Cat.No: T3667
Synonym: Ddhads,穿琥宁,Dehydroandrographolide Succinate Potasium Salt
Target: Others
Deoxyandrographolide
Cat.No: TQ0218
Synonym: 去氧穿心莲内酯,14-deoxyandrographolide
Target: IL Receptor, TNF
Borapetoside B
Cat.No: TN3530
Synonym:
Target: Others
Isoandrographolide
Cat.No: T72580
Synonym:
Target:
Andrographidine A
Cat.No: TN6599
Synonym:
Target:
14-Deoxy-17-hydroxyandrographolide
Cat.No: TN2623
Synonym:
Target: Antifection
Rauvotetraphylline A
Cat.No: TN4895
Synonym:
Target: Others
Dehydroandrographolide
Cat.No: T2738
Synonym:
Target: NOS, Influenza Virus
Bisandrographolide C
Cat.No: T13582
Synonym:
Target: Others
Isomitraphylline
Cat.No: TN4311
Synonym:
Target: Others
Demethoxyrapamycin
Cat.No: T25305
Synonym: AY 24668,AY24668,AY-24668
Target:
9-Oxoageraphorone
Cat.No: TN3329
Synonym:
Target: Others
14-Deoxy-11-hydroxyandrographolide
Cat.No: TN5585
Synonym:
Target:
1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine
Cat.No: TN6038
Synonym:
Target:
14-Deoxy-11,12-didehydroandrographiside
Cat.No: TN2622
Synonym:
Target: Others
Rauvotetraphylline B
Cat.No: TN4896
Synonym:
Target: Others
Borapetoside D
Cat.No: TN3531
Synonym:
Target: Others
Andrographiside
Cat.No: TN3412
Synonym:
Target: Others
Borapetoside F
Cat.No: TN3533
Synonym:
Target: Others
Andrographidine C
Cat.No: TN3411
Synonym:
Target: Others
Bisandrographolide A
Cat.No: TN3518
Synonym:
Target: Others
14-Deoxy-11-oxoandrographolide
Cat.No: TN2463
Synonym:
Target: Others
Rauvotetraphylline E
Cat.No: TN6029
Synonym:
Target:
Rauvotetraphylline C
Cat.No: TN4897
Synonym:
Target: Others
Dehydroborapetoside B
Cat.No: TN3795
Synonym:
Target: Others
Caraphenol A
Cat.No: TN5636
Synonym:
Target:
14-Deoxy-12-hydroxyandrographolide
Cat.No: TN5586
Synonym:
Target:
Borapetoside E
Cat.No: TN3532
Synonym:
Target: Others
Isocarapanaubine
Cat.No: TN4269
Synonym:
Target: Others
Auraptenol
Cat.No: TN1415
Synonym: 酸橙素烯醇
Target: 5-HT Receptor
9-Oxo-10,11-dehydroageraphorone
Cat.No: TN5336
Synonym: 4,7(11)-Cadinadiene-3,8-dione,DTD,7,11-Dehydro-8-oxoageraphorone,泽兰二酮
Target:
Cat. No. Product Name Species Expression System
TMPY-00992 ERAP2 Protein, Human, Recombinant (His)

L-RAP,endoplasmic reticulum aminopeptidase 2,FLJ236...

Human HEK293 Cells
Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum (ER) processing antigenic peptides presented to major histocompatibility complex (MHC) class I molecules. It is a 96-amino acid protein with significant homology to placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase. LRAP preferentially hydrolyz...
TMPY-01732 LRPAP1 Protein, Mouse, Recombinant (His)

C77774,AU042172,RAP,AI790446,low density lipoprotei...

Mouse HEK293 Cells
LRPAP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.4 kDa and the accession number is P55302.
TMPY-01233 LRPAP1 Protein, Human, Recombinant (His)

HBP44,MYP23,low density lipoprotein receptor-related protein...

Human HEK293 Cells
LRPAP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is P30533.
TMPY-04580 IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)

AI255955,6430709H04Rik,IL-1RAcP,AV239853,interleukin 1 recep...

Mouse HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.7 kDa and the accession number is Q3UEL3.
TMPY-01446 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)

IL-18Rbeta,CD218b,IL-18R β/IL-18RAP,IL-18Rβ,ACPL,IL...

Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is O95256-1.
TMPY-05840 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)

interleukin 1 receptor accessory protein

Cynomolgus HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1.
TMPY-05593 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated

IL-1RAcP,interleukin 1 receptor accessory protein,C3orf13,IL...

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9NPH3-1.
TMPY-03102 IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)

interleukin 18 receptor accessory protein,IL-18R β/IL-18...

Rhesus HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.4 kDa and the accession number is XP_001108108.1.
TMPK-00514 IL-18RAP Protein, Cynomolgus, Recombinant (His)

IL-18RAcP,IL-1R7,IL-18R-β,IL-18Rbeta,IL18RAP,IL18RB...

Cynomolgus HEK293 Cells
IL-18RAP, also known as IL-18Rβ or IL-1R7, is component of IL-18 receptor complex and its interactions with IL-18R1 mediate signal transduction initiated by IL-18 although it does not directly bind IL-18 in vitro.
TMPJ-00344 IL-18RAP Protein, Human, Recombinant (hFc & His)

IL-1R accessory protein-like,Interleukin-18 receptor β,C,IL1...

Human HEK293 Cells
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
TMPY-05839 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (hFc)

interleukin 1 receptor accessory protein

Cynomolgus HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.84 kDa and the accession number is P59822-1.
TMPY-06750 IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)

interleukin 18 receptor accessory protein,IL-18R β/IL-18...

Rabbit HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.22 kDa and the accession number is G1SQ92.
TMPY-06761 IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His)

interleukin 18 receptor accessory protein,IL-18R β/IL-18...

Rat HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.28 kDa and the accession number is A0A0G2K2K7.
TMPK-00330 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi)

C3orf13,IL-1 R3,IL1RAP,IL-1RAP,IL-1 RAcP

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is Q9NPH3-1.
TMPY-00609 IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His)

interleukin 18 receptor accessory protein,AcPL,IL-18R β/IL-1...

Mouse Baculovirus Insect Cells
IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 40.1 kDa and the accession number is Q0VBK3.
TMPH-03316 IL-1RAP/IL-1RAcP Protein, Rat, Recombinant (His & Myc)

Rat E. coli
IL-1RAP/IL-1RAcP Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.5 kDa and the accession number is Q63621.
TMPJ-01346 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc & His)

IL-1RAcP,IL-1R3,IL1RAP,Interleukin-1 Receptor Acces...

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 80-100 KDa and the accession number is Q9NPH3-2.
TMPY-05392 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc)

C3orf13,IL1R3,interleukin 1 receptor accessory protein,IL-1R...

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.8 kDa and the accession number is Q9NPH3-1.
TMPY-01251 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His)

C3orf13,IL-1RAcP,interleukin 1 receptor accessory protein,IL...

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.7 kDa and the accession number is Q9NPH3-1.
TMPY-03103 IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His)

interleukin 18 receptor accessory protein,IL-18R β/IL-18...

Rhesus HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.85 kDa and the accession number is XP_001108108.1.
TMPY-04579 IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (hFc)

AI255955,IL-1RAcP,6430709H04Rik,AV239853,interleukin 1 recep...

Mouse HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q3UEL3.
TMPY-01200 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)

IL-1R-7,IL-1R7,interleukin 18 receptor accessory protein,IL-...

Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.2 kDa and the accession number is O95256-1.
TMPY-06312 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated

ACPL,CDw218b,IL-18RAcP,IL-18R-β,IL-1R-7,IL-1RAcPL,CD218b,IL-...

Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.76 kDa and the accession number is NP_003844.1.
TMPY-06316 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated

IL-18Rbeta,IL-18R β/IL-18RAP,IL-1R7,IL18RB,IL-18RAc...

Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 67.04 kDa and the accession number is NP_003844.1.
TMPK-00654 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His)

C3orf13,IL-1 RAcP,IL-1 R3,IL-1RAP,IL1RAP

Cynomolgus HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 40.49 kDa and the accession number is G7NYP7.
TMPJ-01347 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His)

IL1RAP,Interleukin-1 Receptor Accessory Protein,IL-...

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-70 KDa and the accession number is Q9NPH3-2.
TMPK-01029 IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)

C3orf13,IL1RAP,IL-1 R3,IL-1 RAcP

Mouse HEK293 Cells
Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disease pathogenesis. For example, in asthma, both IL-33 and IL-1 are of major importance, as are IL-36 and IL-1 in psoriasis.
TMPK-00331 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated

C3orf13,IL-1 R3,IL-1 RAcP,IL-1RAP,IL1RAP

Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is Q9NPH3-1.
TMPY-01036 IL-1RAPL1 Protein, Human, Recombinant (His)

MRX21,TIGIRR-2,MRX10,MRX34,IL1R8,IL1RAPL,OPHN4,inte...

Human HEK293 Cells
IL-1RAPL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is Q9NZN1.
TMPJ-00016 GABARAP Protein, Human, Recombinant (GST)

GABARAP,GABA(A) Receptor-Associated Protein,GABA

Human E. coli
GABARAP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37 KDa and the accession number is Q6IAW1.
TMPY-03048 PRAP1 Protein, Human, Recombinant (mFc)

UPA,proline-rich acidic protein 1,PRO1195

Human HEK293 Cells
PRAP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41.4 kDa and the accession number is AAL16670.1.
TMPH-00062 Icarapin Protein, Apis mellifera carnica, Recombinant (His & Myc)

Apis mellifera carnica E. coli
Icarapin Protein, Apis mellifera carnica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.7 kDa and the accession number is Q5EF78.
TMPJ-00015 GABARAP Protein, Human, Recombinant (His & hFc)

GABA(A) Receptor-Associated Protein,HCG1987397 Isoform CRA_b...

Human E. coli
GABARAP Protein, Human, Recombinant (His & hFc) is expressed in E. coli expression system with N-6xHis and C-Fc tag. The predicted molecular weight is 50 KDa and the accession number is Q6IAW1.
TMPH-01428 TRAP1 Protein, Human, Recombinant (GST)

Human E. coli
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. TRAP1 Protein, Human, Recombinant (GST) is expressed in E. coli expressi...
TMPY-03268 GABARAPL1 Protein, Human, Recombinant (His)

GEC1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GABA(A) receptor-assoc...

Human E. coli
ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient deple...
TMPY-00587 GABARAP Protein, Human, Recombinant (His & MBP)

GABARAP-a,GABA(A) receptor-associated protein,ATG8A...

Human E. coli
The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential...
TMPY-02117 Marapsin Protein, Human, Recombinant (His)

UNQ1884/PRO4327,protease, serine 27,CAPH2,MPN

Human HEK293 Cells
The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most stro...
TMPY-02547 IL-1RAPL1 Protein, Mouse, Recombinant (hFc)

6330532G10Rik,C030039N24,IL1RAPL,IL1R8,MRX34,OPHN4,...

Mouse HEK293 Cells
IL-1RAPL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is P59823.
TMPH-02267 AGTRAP Protein, Human, Recombinant (His & Myc & SUMO)

ATRAP,AT1 receptor-associated protein,Type-1 angiot...

Human E. coli
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
TMPH-03231 AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)

Cysteine-rich antifungal protein 2,Defensin-like protein 2,R...

Raphanus sativus E. coli
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P30230.
TMPH-00818 Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO)

Kappa-TRTX-Hm1a,Delta-TRTX-Hm1a,Heteroscodratoxin-1,Kappa-th...

Heteroscodra maculata E. coli
Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-Myc tag. The predicted molecular weight is 21.5 kDa and the accession number is P60992.
TMPY-03076 PRAP1 Protein, Human, Recombinant (His)

UPA,PRO1195,proline-rich acidic protein 1

Human HEK293 Cells
PRAP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is AAL16670.1.
TMPY-01117 MRAP Protein, Human, Recombinant (hFc)

FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2...

Human HEK293 Cells
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece...
TMPH-02819 Otoraplin Protein, Mouse, Recombinant (His)

Mouse P. pastoris (Yeast)
Otoraplin Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 14.0 kDa and the accession number is Q9JIE3.
TMPY-03461 GABARAPL2 Protein, Human, Recombinant (His)

GATE16,ATG8,ATG8C,GEF-2,GATE-16,GEF2,GABA(A) receptor-associ...

Human E. coli
GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
TMPY-00985 IL-1RAPL1 Protein, Human, Recombinant (hFc)

IL1R8,MRX21,interleukin 1 receptor accessory protein-like 1,...

Human HEK293 Cells
IL-1RAPL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q9NZN1.

重组蛋白

ERAP2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00992
Species: Human
Expression System: HEK293 Cells
LRPAP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01732
Species: Mouse
Expression System: HEK293 Cells
LRPAP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01233
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04580
Species: Mouse
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
Cat.No: TMPY-01446
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05840
Species: Cynomolgus
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05593
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03102
Species: Rhesus
Expression System: HEK293 Cells
IL-18RAP Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00514
Species: Cynomolgus
Expression System: HEK293 Cells
IL-18RAP Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00344
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-05839
Species: Cynomolgus
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-06750
Species: Rabbit
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His)
Cat.No: TMPY-06761
Species: Rat
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00330
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00609
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-1RAP/IL-1RAcP Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03316
Species: Rat
Expression System: E. coli
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-01346
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05392
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His)
Cat.No: TMPY-01251
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03103
Species: Rhesus
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04579
Species: Mouse
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01200
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06312
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06316
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His)
Cat.No: TMPK-00654
Species: Cynomolgus
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His)
Cat.No: TMPJ-01347
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)
Cat.No: TMPK-01029
Species: Mouse
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated
Cat.No: TMPK-00331
Species: Human
Expression System: HEK293 Cells
IL-1RAPL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01036
Species: Human
Expression System: HEK293 Cells
GABARAP Protein, Human, Recombinant (GST)
Cat.No: TMPJ-00016
Species: Human
Expression System: E. coli
PRAP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03048
Species: Human
Expression System: HEK293 Cells
Icarapin Protein, Apis mellifera carnica, Recombinant (His & Myc)
Cat.No: TMPH-00062
Species: Apis mellifera carnica
Expression System: E. coli
GABARAP Protein, Human, Recombinant (His & hFc)
Cat.No: TMPJ-00015
Species: Human
Expression System: E. coli
TRAP1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01428
Species: Human
Expression System: E. coli
GABARAPL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03268
Species: Human
Expression System: E. coli
GABARAP Protein, Human, Recombinant (His & MBP)
Cat.No: TMPY-00587
Species: Human
Expression System: E. coli
Marapsin Protein, Human, Recombinant (His)
Cat.No: TMPY-02117
Species: Human
Expression System: HEK293 Cells
IL-1RAPL1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02547
Species: Mouse
Expression System: HEK293 Cells
AGTRAP Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02267
Species: Human
Expression System: E. coli
AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)
Cat.No: TMPH-03231
Species: Raphanus sativus
Expression System: E. coli
Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00818
Species: Heteroscodra maculata
Expression System: E. coli
PRAP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03076
Species: Human
Expression System: HEK293 Cells
MRAP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01117
Species: Human
Expression System: HEK293 Cells
Otoraplin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02819
Species: Mouse
Expression System: P. pastoris (Yeast)
GABARAPL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03461
Species: Human
Expression System: E. coli
IL-1RAPL1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00985
Species: Human
Expression System: HEK293 Cells
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