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70

抑制剂 & 化合物

61

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9331	Bemnifosbuvir hemisulfate AT-527	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Bemnifosbuvir hemisulfate (AT-527) 是一种 HCV 病毒复制抑制剂。
T7942	Tranylcypromine hemisulfate Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐	Histone Demethylase; MAO; Monoamine Oxidase	Chromatin/Epigenetic; Metabolism; Neuroscience
	Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂，可用于研究抑郁症和子宫内膜异位症。
T6652	Salbutamol hemisulfate Ventolin Sulfate,沙丁胺醇半硫酸盐,Albuterol,Salbutamol Sulfate,硫酸沙丁胺醇,Bronchospray,Albuterol Sulfate	Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Salbutamol hemisulfate (Albuterol Sulfate) 是一种短效的β2肾上腺素受体激动剂，IC50 为 8.93 μM。
T0438	Proflavine Hemisulfate 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate,硫酸原黄素	Others; Potassium Channel; DNA; Thrombin; Antibacterial; Autophagy	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Others; Proteases/Proteasome
	Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) 是一种 DNA 嵌入剂，也是一种吖啶染料。它是抗菌剂，也可作为 Kir3.2孔阻滞剂，可研究与 Kir3.2 相关的神经系统疾病。
T61107	Tilomisole Wy 18251	Others	Others
	Tilomisole (Wy 18251) 是一种可口服的苯并咪唑噻唑，具有抗炎活性和免疫调节活性。Tilomisole 可用于研究癌症和炎症。
T10305	Amiselimod hydrochloride MT-1303 hydrochloride	S1P Receptor; LPL Receptor	GPCR/G Protein
	Amiselimod hydrochloride (MT-1303 hydrochloride) 是一种鞘氨醇 1-磷酸受体 1 (S1P1) 调节剂。
T7165	Basmisanil RG1662,RO5186582,巴米沙尼	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Basmisanil (RG1662) 是高度选择性GABAAα5负调节剂，用于治疗与唐氏综合症相关的认知障碍。
T28437	Pomisartan BIBR-363,BIBR 363,BIBR363	RAAS	Endocrinology/Hormones
	Pomisartan (BIBR-363) 是一种小分子血管紧张素 1 型受体(AT1R)拮抗剂，可用于治疗心血管疾病，研究心脏衰竭和高血压。
T67509	Cholesteryl Hemisuccinate Cholesterol hydrogen succinate	Apoptosis; DNA/RNA Synthesis; Topoisomerase	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) 是一种经常使用在极性溶液中具有高溶解度的胆固醇类似物，具有保肝、抗癌和抑制肿瘤生长的作用。Cholesteryl Hemisuccinate 抑制对乙酰氨基酚的肝毒性，并防止 AAP 诱导的肝细胞凋亡和坏死。Cholesteryl Hemisuccinate 抑制 DNA 聚合酶和 DNA 拓扑异构酶，从而抑制 DNA 复制和修复以及细胞分裂。
T14324	Artemisone BAY 44-9585,Artemifone,青蒿酮	Others; Parasite	Microbiology/Virology; Others
	Artemisone (BAY 44-9585) 是一种半合成的有效抗疟疾剂，还是一种人CMV 的有效抑制剂，可抑制多种P. falciparum，平均IC50值为 0.83 nM。
T9604	beta-Estradiol 17-hemisuccinate	Estrogen Receptor/ERR	Endocrinology/Hormones
	beta-Estradiol 17-hemisuccinate 选择性染色富含雌激素受体 (ER) 的细胞。
T26375	(S)-Amisulpride Esamisulpride,(S) Amisulpride,SEP-4199,(S)-氨磺必利	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	(S)-Amisulpride ((S) Amisulpride) 是一种有效的多巴胺D2/D3受体拮抗剂，具有抗精神和抗抑郁作用。它是5-HT7受体的拮抗剂，KI 值为 900 nM。
T4602	Hydrocortisone hemisuccinate Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate	Glucocorticoid Receptor; Others; Interleukin	Endocrinology/Hormones; Immunology/Inflammation; Others
	Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素，是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性，可用于研究溃疡性结肠炎。
T21899	Misonidazole SR-1354,SR1354,Ro 7-0582	GPX	oxidation-reduction
	Misonidazole 是一种缺氧肿瘤细胞放射增敏剂，具有抗菌活性。
TF0106	Cholesteryl Hemisuccinate Tris Salt	Apoptosis	Apoptosis
	Cholesteryl Hemisuccinate Tris Salt 是一种具有保肝和抗癌活性的酸性胆固醇酯，是一种含有柴胡皂苷-d的二棕榈酰磷脂酰胆碱脂质体中的膜稳定剂，可增强顺铂的抗癌功效。Cholesteryl hemisuccinate 具有抗肿瘤活性，抑制肿瘤生长，抑制对乙酰氨基酚 (AAP) 的肝毒性，预防 AAP 诱导的肝细胞凋亡。Cholesteryl hemisuccinate 可保护啮齿动物免受对乙酰氨基酚、阿霉素、四氯化碳、氯仿和半乳糖胺的毒性作用。
T0294	6α-Methylprednisolone 21-hemisuccinate sodium salt Asmacortone,Methylprodnisolone Sodium Succinate,甲强龙琥珀酸钠,Metypresol,Methylprednisolone sodium succinate,Corticel,6-Methylprednisolone succinate sodium	Glucocorticoid Receptor; Glucagon Receptor	Endocrinology/Hormones; GPCR/G Protein
	6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone) 是一种糖皮质激素，是一种有效的抗炎剂，半衰期比 Prednisolone 长。
T26308	Lipoxamycin hemisulfate Lipoxamycin, sulfate (2:1),U-26146D,U26146D,U 26146D,Lipoxamycin	Antifungal	Microbiology/Virology
	Lipoxamycin hemisulfate (Lipoxamycin) 是一种丝氨酸棕榈酰转移酶抑制剂 (IC50 = 21 nM)，具有抗真菌活性。
T7887	8-Hydroxyquinoline hemisulfate 8-羟基喹啉硫酸盐,Oxyquinoline sulfate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	8-Hydroxyquinoline hemisulfate (Oxyquinoline sulfate) 是一种单质子双齿螯合剂，具有温和的抑菌、驱虫和杀螨作用。
T77507	(-)-Benzotetramisole
	(-)-Benzotetramisole 使一种高效且具有选择性的催化剂。(-)-Benzotetramisole 是抗蠕虫化合物四咪唑3 的苯annulated 衍生物，本身也是转化的有效催化剂。
T33836L	Oxamisole TFA Oxamisole TFA（99258-56-7 Free base)	Antiviral	Immunology/Inflammation
	Oxamisole TFA 是一种可口服且具有选择性的 T 细胞免疫调节剂，可用于研究病毒感染。
T28437L	Pomisartan 2HCl Pomisartan 2HCl(144702-17-0 Free base),BIBR363 2HCL	RAAS	Endocrinology/Hormones
	Pomisartan 2HCl（BIBR363 2HCl）是一种小分子AT1R拮抗剂，用于研究心力衰竭和高血压。
T1570	Telmisartan BIBR 277,替米沙坦	RAAS; Autophagy	Autophagy; Endocrinology/Hormones
	Telmisartan (BIBR 277) 是一种血管紧张素II 1型受体拮抗剂，能够抑制其活性，IC50值为 9.2 nM。
T6157	Devimistat CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis; Dehydrogenase; Mitochondrial Metabolism	Apoptosis; Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) 是一种线粒体代谢抑制剂，还是一种lipoic acid 拮抗剂，能阻断线粒体能量代谢，诱导多种癌细胞凋亡。
T0227	Bromisoval 2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,溴米那,BRN 1773255,Bromovalerylurea,溴米索伐,Bromaral	Others	Others
	Bromisoval (Isobromyl) 具有抗炎活性。
T6353	(-)-p-Bromotetramisole Oxalate (-)-对溴四咪唑草酸盐,L-p-Bromotetramisole oxalate,6-Bromolevamisole oxalate,(-)-p-Bromolevamisole oxalate	Phosphatase; Phosphorylase	Metabolism
	(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) 是一种强效的、非特异性碱性磷酸酶抑制剂。
T21967	MEG hemisulfate Mercaptoethylguanidine hemisulfate	NOS	Immunology/Inflammation
	MEG hemisulfate (Mercaptoethylguanidine hemisulfate) 是一种有效和选择性的诱导型 NO 合酶 (iNOS) 的抑制剂，在组织匀浆中抑制 iNOS，ecNOS 和 bNOS 的 EC50 值分别为 11.5，110 和 60 μM。MEG hemisulfate 也有效的过氧亚硝酸盐清除剂，可抑制过氧亚硝酸盐诱导的氧化过程。MEG hemisulfate 在许多炎症实验模型中具有保护作用，包括缺血/再灌注损伤，牙周炎，失血性休克，炎性肠病以及内毒素和败血性休克。
T0811	Amisulpride DAN 2163,氨磺必利,阿米舒必利	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Amisulpride (DAN 2163) 是多巴胺D2/D3受体拮抗剂，对于人多巴胺D2和D3的Ki 分别为 2.8 和 3.2 nM。
T0277	Metaproterenol hemisulfate Orciprenaline sulfate,Metaproterenol Sulfate,硫酸奥西那林	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Metaproterenol hemisulfate (Orciprenaline sulfate) 是一种 β2-肾上腺素能受体 (β2AR) 激动剂(IC50=68 nM)，是一种直接作用的拟交感神经药，具有抗炎活性。
T7348	Imisopasem manganese M40403,伊米帕锰	Others	Others
	Imisopasem manganese (M40403) is a manganese superoxide MnSOD non-peptidyl mimetic.
T31825	Fluoromisonidazole
	Fluoromisonidazole, a Radiation-Sensitizing Agent, can be used for imaging tumor hypoxia: imaging the microenvironment for personalized cancer therapy.
T74219	Maximiscin
	Maximiscin 是一种真菌代谢产物，可诱导DNA damage 损伤，并对一种三阴性乳腺癌亚型显示出选择性的细胞毒活性。
T124658	Phlomisionoside
	Phlomisionoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124658，CAS号为 558451-77-7。
T70595	Artemisinin B
	Artemisinin B is a drug which may improve spatial memory in dementia patients and alter the levels of inflammatory cytokines in the hippocampus and the cortex. Artemisinin B may inhibit neuroinflammation and exert neuroprotective effects on cognitive functions by modulating the TLR4-MyD88-NF-κB signaling pathway. Artemisinin B has shown potential in the treatment of neuroinflammatory diseases.
T124866	Pyrochamissanthin
	Pyrochamissanthin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124866。
T12047	Misoprostol acid	Others	Others
	Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers.
T124224	Angeloylgomisin P
	Angeloylgomisin P 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124224，CAS号为 77881-08-4。
T69224	Hemisurfen
	Hemisurfen is a small molecule, surfen derivative with heparan sulfate antagonist properties.
T61740	Esomeprazole hemistrontium
	Esomeprazole hemistrontium, also known as (S)-Omeprazole, is a potent and orally active proton pump inhibitor that effectively reduces acid secretion by inhibiting the H+, K+-ATPase in gastric parietal cells. This compound exhibits promising potential for research in symptomatic gastroesophageal reflux disease [1] [2] [3].
T27570	Ianthelliformisamine B TFA Ianthelliformisamine-B TFA,IanthelliformisamineB TFA,Ianthelliformisamine B TFA salt
	Ianthelliformisamine B TFA, an antibiotic enhancer, is used to against resistant Gram-negative bacteria.
T2573	Misoprostol	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Misoprostol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T2573，CAS号为 59122-46-2。
T72879	Misetionamide
	Misetionamide，一种恶噻嗪类口服化合物，作为甘油醛-3-磷酸脱氢酶 (GAPDH) 抑制剂，展现出抗肿瘤活性，适用于癌症研究。
T130879	Altamisic acid
	Altamisic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T130879。
T131541	Artemisinin (Arteannuin, Qinghaosu, Qing Hau Sau)
	Artemisinin (Arteannuin, Qinghaosu, Qing Hau Sau) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131541。
T126190	Vermisporin
	Vermisporin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126190。
T29995	Amisometradine Aminoisometradin,Aminoisometradine,Rolicton
	Amisometradine is a diuretic which may be used in the treatment of congestive heart failure.
T37288	Remisporine B
	Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 μg/ml, respectively).1 1.Liu, H., Chen, S., Liu, W., et al.Polyketides with immunosuppressive activities from mangrove endophytic fungus Penicillium sp. ZJ-SY2Mar. Drugs14(12)217(2016) 2.Kong, F., and Carter, G.T.Remisporine B, a novel dimeric chrom...
T33401	Missourin
	Missouri is a triterpenoid derived from the root of the Missouri iris. In addition, two known triterpenes, iso-iridogermanal, and zeorin, were isolated and identified.
T33396	Misakimycin
	Misakimycin is a mammalian cell growth stimulating substance produced by Streptomyces misakiensis BP-3621.
T33836	Oxamisole PR 879-317A,Oxamisol
	Oxamisole is an immunoregulator that has immunorestorative effects on T-cells.
T21276	Amisulbrom
	Amisulbrom is classified under the triazole group of fungicides.

化合物

Bemnifosbuvir hemisulfate

Cat.No: T9331

Synonym: AT-527

Target: HCV Protease, SARS-CoV

Tranylcypromine hemisulfate

Cat.No: T7942

Synonym: Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐

Target: Histone Demethylase, MAO, Monoamine Oxidase

Salbutamol hemisulfate

Cat.No: T6652

Synonym: Ventolin Sulfate,沙丁胺醇半硫酸盐,Albuterol,Salbutamol Sulfate,硫酸沙丁胺醇,Bronchospray,Albuterol Sulfate

Target: Adrenergic Receptor, Autophagy

Proflavine Hemisulfate

Cat.No: T0438

Synonym: 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate,硫酸原黄素

Target: Others, Potassium Channel, DNA, Thrombin, Antibacterial, Autophagy

Cat.No: T61107

Synonym: Wy 18251

Target: Others

Amiselimod hydrochloride

Cat.No: T10305

Synonym: MT-1303 hydrochloride

Target: S1P Receptor, LPL Receptor

Cat.No: T7165

Synonym: RG1662,RO5186582,巴米沙尼

Target: GABA Receptor

Cat.No: T28437

Synonym: BIBR-363,BIBR 363,BIBR363

Target: RAAS

Cholesteryl Hemisuccinate

Cat.No: T67509

Synonym: Cholesterol hydrogen succinate

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase

Cat.No: T14324

Synonym: BAY 44-9585,Artemifone,青蒿酮

Target: Others, Parasite

beta-Estradiol 17-hemisuccinate

Cat.No: T9604

Target: Estrogen Receptor/ERR

(S)-Amisulpride

Cat.No: T26375

Synonym: Esamisulpride,(S) Amisulpride,SEP-4199,(S)-氨磺必利

Target: Dopamine Receptor, 5-HT Receptor

Hydrocortisone hemisuccinate

Cat.No: T4602

Synonym: Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate

Target: Glucocorticoid Receptor, Others, Interleukin

Cat.No: T21899

Synonym: SR-1354,SR1354,Ro 7-0582

Target: GPX

Cholesteryl Hemisuccinate Tris Salt

Cat.No: TF0106

Target: Apoptosis

6α-Methylprednisolone 21-hemisuccinate sodium salt

Cat.No: T0294

Synonym: Asmacortone,Methylprodnisolone Sodium Succinate,甲强龙琥珀酸钠,Metypresol,Methylprednisolone sodium succinate,Corticel,6-Methylprednisolone succinate sodium

Target: Glucocorticoid Receptor, Glucagon Receptor

Lipoxamycin hemisulfate

Cat.No: T26308

Synonym: Lipoxamycin, sulfate (2:1),U-26146D,U26146D,U 26146D,Lipoxamycin

Target: Antifungal

8-Hydroxyquinoline hemisulfate

Cat.No: T7887

Synonym: 8-羟基喹啉硫酸盐,Oxyquinoline sulfate

Target: Others, Antibacterial, Antibiotic

(-)-Benzotetramisole

Cat.No: T77507

Cat.No: T33836L

Synonym: Oxamisole TFA（99258-56-7 Free base)

Target: Antiviral

Pomisartan 2HCl

Cat.No: T28437L

Synonym: Pomisartan 2HCl(144702-17-0 Free base),BIBR363 2HCL

Target: RAAS

Cat.No: T1570

Synonym: BIBR 277,替米沙坦

Target: RAAS, Autophagy

Cat.No: T6157

Synonym: CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism

Cat.No: T0227

Synonym: 2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,溴米那,BRN 1773255,Bromovalerylurea,溴米索伐,Bromaral

Target: Others

(-)-p-Bromotetramisole Oxalate

Cat.No: T6353

Synonym: (-)-对溴四咪唑草酸盐,L-p-Bromotetramisole oxalate,6-Bromolevamisole oxalate,(-)-p-Bromolevamisole oxalate

Target: Phosphatase, Phosphorylase

MEG hemisulfate

Cat.No: T21967

Synonym: Mercaptoethylguanidine hemisulfate

Target: NOS

Cat.No: T0811

Synonym: DAN 2163,氨磺必利,阿米舒必利

Target: Dopamine Receptor, 5-HT Receptor

Metaproterenol hemisulfate

Cat.No: T0277

Synonym: Orciprenaline sulfate,Metaproterenol Sulfate,硫酸奥西那林

Target: Adrenergic Receptor

Imisopasem manganese

Cat.No: T7348

Synonym: M40403,伊米帕锰

Target: Others

Fluoromisonidazole

Cat.No: T31825

Cat.No: T74219

Phlomisionoside

Cat.No: T124658

Cat.No: T70595

Pyrochamissanthin

Cat.No: T124866

Misoprostol acid

Cat.No: T12047

Target: Others

Angeloylgomisin P

Cat.No: T124224

Cat.No: T69224

Esomeprazole hemistrontium

Cat.No: T61740

Ianthelliformisamine B TFA

Cat.No: T27570

Synonym: Ianthelliformisamine-B TFA,IanthelliformisamineB TFA,Ianthelliformisamine B TFA salt

Cat.No: T2573

Target: Prostaglandin Receptor

Misetionamide

Cat.No: T72879

Cat.No: T130879

Artemisinin (Arteannuin, Qinghaosu, Qing Hau Sau)

Cat.No: T131541

Cat.No: T126190

Cat.No: T29995

Synonym: Aminoisometradin,Aminoisometradine,Rolicton

Cat.No: T37288

Cat.No: T33401

Cat.No: T33396

Cat.No: T33836

Synonym: PR 879-317A,Oxamisol

Cat.No: T21276

Cat. No.	Product Name	Target	Signaling Pathways
T5S0106	Peimisine 贝母辛,Ebeiensine	RAAS; AChR	Endocrinology/Hormones; Neuroscience
	Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体，抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放，促进一氧化氮释放，可舒张气管平滑肌，有平喘作用。
TN1036	Gomisin D 戈米辛 D,戈米辛D	Others	Others
	Gomisin D 是一种分离自五味子中的木脂素。它抑制 UDP-葡糖醛酸基转移酶活性，清除 ABTS(+) 自由基。它是生脉散和参芪降糖颗粒的质量标志物，具有成为抗糖尿病药和抗阿尔茨海默病药的潜力。
T21065	Artemisitene	Others	Others
	Artemisitene 是青蒿素的氧化形式，是一种抗疟药。青蒿素前体是青蒿素生物合成的重要基础物质，包括青蒿素 B、青蒿素、青蒿酸等。
T8297	Gomisin N	Apoptosis	Apoptosis
	Gomisin N 是从五味子中分离得到的一种天然产物，有镇静和催眠生物活性。它具有用于治疗过敏和抑制癌症增殖和诱导细胞凋亡的潜力。
T0392	Artemisinin Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine	HCV Protease; Ferroptosis; Akt; Parasite	Apoptosis; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Artemisinin (Qinghaosu) 是一种倍半萜烯内酯，是从青蒿植物的地上部分分离的一种抗疟疾药物。它有神经保护和抗癌作用。
T6369	Adenine hemisulfate 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hemisulfate (Diadenine sulphate) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
TN1568	Deoxyartemisinin 2-deoxyartemisinin
	Deoxyartemisinin (2-deoxyartemisinin) 是一种口服有效的抗炎和抗溃疡化合物，可从青蒿素青蒿中分离得到。
TN1709	Gomisin O 5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-5-ol,戈米辛 O	Others	Others
	Gomisin O (5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-5-ol) 是一种分离自五味子果实的物质。
TN2272	Tigloylgomisin H	Nrf2	Immunology/Inflammation
	Tigloylgomisin H 是分离自S. chinensis 果实中的木酚素。Tigloylgomisin H 能诱导小鼠肝癌细胞 Hepa1c1c7 中醌还原酶活性。Tigloylgomisin H 是单功能诱导剂，通过 Nrf2-ARE 途径特异性上调 II 期解毒酶 NQO1。Tigloylgomisin H 是潜在的肝癌预防剂。
TN1018	Angeloylgomisin H 当归酰戈米辛 H,当归酰戈米辛H	PPAR	DNA Damage/DNA Repair; Metabolism
	Angeloylgomisin H 是从五味子中提取的一种木脂素类天然产物。它通过激活PPAR-γ来改善胰岛素刺激的葡萄糖摄取潜力。
TN1390	Angeloylgomisin Q 当归酰基戈米辛Q,当归酰戈米辛Q	Others	Others
	Angeloylgomisin Q 是一种新二苯并环辛二烯类木脂素，提取自五味子茎中。它具有用于阿尔茨海默病研究的潜力。
T0607	Dihydroartemisinin 双氢青蒿素,β-Dihydroartemisinin,Dihydroqinghaosu,Artenimol,DHA	Apoptosis; NF-κB; Parasite; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; NF-κB
	Dihydroartemisinin (Artenimol) 是一种抗疟疾药物。
TQ0217	Gomisin G 戈米辛G,戈米辛 G	P450; HIV Protease	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Gomisin G 是一种有抗HIV 活性的天然产物。
TN3396	Alpinumisoflavone acetate 4'-O-Acetylalpinumisoflavone	Others	Others
	Alpinumisoflavone acetate (4'-O-Acetylalpinumisoflavone) 是一种新的alpinumisoflavone 衍生物。Alpinumisoflavone 在0.63 ug/disc 时强烈抑制生殖管生长。
T3904	Gomisin J	Calcium Channel; AMPK	Chromatin/Epigenetic; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
	Gomisin J 是在五味子中发现的小分子量木脂素，具有血管舒张活性，在非酒精性脂肪性肝病方面有研究潜力。它通过激活 AMPK、LKB1 和 Ca2+/钙调蛋白依赖性蛋白激酶 II 以及抑制 HepG2 细胞中的胎球蛋白 A 来调节脂肪生成酶和脂肪分解酶以及炎症分子的表达，从而抑制脂质积累。
TN1511	Cleomiscosin A	LDL; Antioxidant; TNF	Apoptosis; Metabolism; oxidation-reduction
	Cleomiscosin A 来源于 Acer okamotoanum 的叶和树枝，对小鼠腹腔巨噬细胞的 TNF-α 分泌具有抑制活性。 Cleomiscosin A 可用于预防动脉粥样硬化病变中 LDL 氧化的研究。
T4S1452	Artemisic acid (+)-Artemisinic Acid,青蒿酸,Artemisinic acid	Antibacterial	Microbiology/Virology
	Artemisic acid ((+)-Artemisinic Acid) 是黄花蒿中分离得到的一种倍半萜，具有多种药理活性，如抗疟、抗菌和抗肿瘤活性，以及解热、化感和抗脂肪生成作用。
T6564	Leupeptin Hemisulfate 亮肽素	Serine Protease; Cysteine Protease	Proteases/Proteasome
	Leupeptin hemisulfate 是一种蛋白酶抑制剂，具有细胞膜渗透性、可逆性、竞争性和口服活性。Leupeptin hemisulfate 可以抑制 Cathepsin B、Cathepsin H、Cathepsin L 的活性，阻断两性溶酶体的融合。Leupeptin hemisulfate 还具有抗炎活性。
TN3847	Dihydroalpinumisoflavone
	Dihydroalpinumisoflavone 是一种从 Crotalaria madurensis 的叶子和茎中提取的天然产品。
T7059	α-Dihydroartemisinin α-Artenimol,α-Dihydroqinghaosu	Parasite	Microbiology/Virology
	α-Dihydroartemisinin (α-Dihydroqinghaosu) 是青蒿素类抗疟化合物的中间体，具有良好的抗疟抗癌活性，可用于研究红斑狼疮。
THS1455	DihydroarteMisinic acid 双氢青蒿酸,Dihydro-Artmisinic Acid,二氢青蒿酸	Ferroptosis; Parasite	Apoptosis; Microbiology/Virology
	DihydroarteMisinic acid (Dihydro-Artmisinic Acid) 是青蒿的天然产物，是青蒿素的主要直接前体，青蒿素是一种广泛用于治疗疟疾的药草。
TN1609	Epigomisin O	Others	Others
	Epigomisin O is a natural product from Schizandra chinensis.
TN4294	Isogomisin O	Others	Others
	Isogomisin O是一种天然产物，属于五味子科五味子属，其产品编号为 TN4294，CAS号为 83916-76-1。Isogomisin O可用作对照参考。
TN3493	Benzoylgomisin H	Others	Others
	Benzoylgomisin H is a natural product from Schizandra chinensis.
TN1318	Benzoylgomisin O 苯甲酰戈米辛O,6-O-benzoylgomisin O	Others	Others
	6-O-benzoylgomisin O is a natural product from Schisandra sphenanthera.
TN3384	alpha-Epoxydihydroartemisinic acid	Others	Others
	alpha-Epoxydihydroartemisinic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3384，CAS号为 380487-65-0。
TN5401	R(+)-Gomisin M1 R(+)-戈米辛M1
	(+/-)-Gomisin M1 exhibits potent anti-HIV activity, with EC50 and therapeutic index (TI) values of <0.65 microM and >68, respectively.
TN4821	Pregomisin	PAFR	GPCR/G Protein
	Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M.
T72903	Artemisiane E
	Artemisiane E 是一种有效的PI3K/AKT 通路抑制剂，IC50为 8.9 μM。
TN3827	Demissidine	Others	Others
	Demissidine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3827，CAS号为 474-08-8。
TN3494	Benzoylgomisin P	Others	Others
	Benzoylgomisin P 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3494，CAS号为 129445-43-8。
T13614	Cimiside B	Others	Others
	Cimiside B is a glycoside alkaloid isolated from the rhizome of Cimicifuga dahurica.
TN6541	Cleomiscosin B
	Cleomiscosins A, B and C exhibit liver-protective properties. Cleomiscosin B shows the potent anti-HIV-1 activity in vitro and also has protective effects on MT4 cells infected by HIV-1(IIIB).
TN1389	Angeloylgomisin O 当归酰戈米辛O,当归酰戈米辛 O	Others	Others
	Angeloylgomisin O is a nartural product from Schisandra chinensis.
T38036	Lumisterol
	Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol. Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities[1]. [1]. Anyamanee Chaiprasongsuk, et al. Protective Effects of Novel Derivatives of Vitamin D 3 and Lumisterol Against UVB-induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms. Redox Biol. 2019 Jun;24:101206.
TN4154	Gomisin L1	Others	Others
	(-)-Gomisin L1 induces G2/M arrest and apoptosis in human ovarian cancer cells.
TN4155	Gomisin L2	Others	Others
	Gomisin L2 is a natural product from Schizandra chinensis BAILL.
TN1701	Glycosmisic acid	Others	Others
	Glycosmisic acid is a natural product from Nauclea officinalis.
T81524	Peimisine 3-O-β-D-glucopyranoside
	Peimisine 3-O-β-D-glucopyranoside (compound 1) 是一种从单苞贝母鳞茎中分离得到的甾体生物碱。该化合物对鱼藤酮诱导的PC12细胞系神经毒性展现出中等程度的保护效果。
TN4156	Gomisin U	Others	Others
	Gomisin U 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4156，CAS号为 135095-46-4。
TN6628	Tigloylgomisin O
	Tigloylgomisin O 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6628，CAS号为 130855-74-2。
TN3157	6-Demethoxy-9'-deoxycleomiscosin A	Others	Others
	6-Demethoxy-9'-deoxycleomiscosin A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3157，CAS号为 121587-18-6。
TN3675	Cleomiscosin C	LDL	Metabolism
	Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl ( IC50s of 23.6 and 3.9 microM, respectively), suggests that it could be beneficial in preventing LDL oxidation in atheroscl
TN1708	Gomisin M2 五味子脂素 M2	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Gomisin M2 is an anti-HIV agent.
TN1399	Arenobufagin 3-hemisuberate 沙蟾毒精 3-辛二酸单酯,沙蟾毒精3-辛二酸单酯	Others	Others
	Arenobufagin 3-hemisuberate is a natural product
TN3655	Cimiside E	ERK; TNF; ROS; Akt; PI3K; PKC; PPAR	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agen
TN4153	Gomisin K1	Others	Others
	Gomisin K1 is a natural product from Schizandra chinensis BAILL.
TN2449	Anhydro Dihydro Artemisinin	Others	Others
	Anhydro Dihydro Artemisinin is a natural product from Artemisia carvifolia Buch.-Ham. ex Roxb.
TN1974	Angeloyl-(+)-gomisin K3 Negsehisandrin G,当归酰基-(+)-戈米辛 K3	Others	Others
	Negsehisandrin G is a natural product
TN4152	Gomisin F	Others	Others
	Gomisin F是一种天然产物，属于五味子科五味子属，其产品编号为 TN4152，CAS号为 62956-47-2。Gomisin F可用作对照参考。
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天然产物

Cat.No: T5S0106

Synonym: 贝母辛,Ebeiensine

Target: RAAS, AChR

Cat.No: TN1036

Synonym: 戈米辛 D,戈米辛D

Target: Others

Cat.No: T21065

Target: Others

Cat.No: T8297

Target: Apoptosis

Cat.No: T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

Adenine hemisulfate

Cat.No: T6369

Synonym: 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐

Target: DNA/RNA Synthesis, Endogenous Metabolite

Deoxyartemisinin

Cat.No: TN1568

Synonym: 2-deoxyartemisinin

Cat.No: TN1709

Synonym: 5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-5-ol,戈米辛 O

Target: Others

Tigloylgomisin H

Cat.No: TN2272

Target: Nrf2

Angeloylgomisin H

Cat.No: TN1018

Synonym: 当归酰戈米辛 H,当归酰戈米辛H

Target: PPAR

Angeloylgomisin Q

Cat.No: TN1390

Synonym: 当归酰基戈米辛Q,当归酰戈米辛Q

Target: Others

Dihydroartemisinin

Cat.No: T0607

Synonym: 双氢青蒿素,β-Dihydroartemisinin,Dihydroqinghaosu,Artenimol,DHA

Target: Apoptosis, NF-κB, Parasite, Autophagy

Cat.No: TQ0217

Synonym: 戈米辛G,戈米辛 G

Target: P450, HIV Protease

Alpinumisoflavone acetate

Cat.No: TN3396

Synonym: 4'-O-Acetylalpinumisoflavone

Target: Others

Cat.No: T3904

Target: Calcium Channel, AMPK

Cat.No: TN1511

Target: LDL, Antioxidant, TNF

Cat.No: T4S1452

Synonym: (+)-Artemisinic Acid,青蒿酸,Artemisinic acid

Target: Antibacterial

Leupeptin Hemisulfate

Cat.No: T6564

Synonym: 亮肽素

Target: Serine Protease, Cysteine Protease

Dihydroalpinumisoflavone

Cat.No: TN3847

α-Dihydroartemisinin

Cat.No: T7059

Synonym: α-Artenimol,α-Dihydroqinghaosu

Target: Parasite

DihydroarteMisinic acid

Cat.No: THS1455

Synonym: 双氢青蒿酸,Dihydro-Artmisinic Acid,二氢青蒿酸

Target: Ferroptosis, Parasite

Cat.No: TN1609

Target: Others

Cat.No: TN4294

Target: Others

Benzoylgomisin H

Cat.No: TN3493

Target: Others

Benzoylgomisin O

Cat.No: TN1318

Synonym: 苯甲酰戈米辛O,6-O-benzoylgomisin O

Target: Others

alpha-Epoxydihydroartemisinic acid

Cat.No: TN3384

Target: Others

R(+)-Gomisin M1

Cat.No: TN5401

Synonym: R(+)-戈米辛M1

Cat.No: TN4821

Target: PAFR

Cat.No: T72903

Cat.No: TN3827

Target: Others

Benzoylgomisin P

Cat.No: TN3494

Target: Others

Cat.No: T13614

Target: Others

Cat.No: TN6541

Angeloylgomisin O

Cat.No: TN1389

Synonym: 当归酰戈米辛O,当归酰戈米辛 O

Target: Others

Cat.No: T38036

Cat.No: TN4154

Target: Others

Cat.No: TN4155

Target: Others

Glycosmisic acid

Cat.No: TN1701

Target: Others

Peimisine 3-O-β-D-glucopyranoside

Cat.No: T81524

Cat.No: TN4156

Target: Others

Tigloylgomisin O

Cat.No: TN6628

6-Demethoxy-9'-deoxycleomiscosin A

Cat.No: TN3157

Target: Others

Cat.No: TN3675

Target: LDL

Cat.No: TN1708

Synonym: 五味子脂素 M2

Target: HIV Protease

Arenobufagin 3-hemisuberate

Cat.No: TN1399

Synonym: 沙蟾毒精 3-辛二酸单酯,沙蟾毒精3-辛二酸单酯

Target: Others

Cat.No: TN3655

Target: ERK, TNF, ROS, Akt, PI3K, PKC, PPAR

Cat.No: TN4153

Target: Others

Anhydro Dihydro Artemisinin

Cat.No: TN2449

Target: Others

Angeloyl-(+)-gomisin K3

Cat.No: TN1974

Synonym: Negsehisandrin G,当归酰基-(+)-戈米辛 K3

Target: Others

Cat.No: TN4152

Target: Others

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