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Search Results for " erbb "
Targets Recommended: EGFR

135

抑制剂 & 化合物

11

天然产物

88

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T21954 EGFR/ErbB-2/ErbB-4 inhibitor-2

EGFR/ErbB2 Inhibitor

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) 是EGFR 和ErbB 的抑制剂,对EGFR、ErbB2 和 ErbB4 的IC50分别为 0.017、0.08 和 1.91 μM。
T79861 EGFR/ErbB-2 inhibitor-1

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
EGFR/ErbB-2 inhibitor-1 是一种选择性的 ErbB2/HER2 抑制剂,能有效地阻断ErbB2和HER2的信号传导。
T76542 ErbB-2-binding peptide

ErbB-2-binding peptide (HER2-binding peptide)为具结合肿瘤功能的肽类,其在癌症研究中显示出应用潜力。
T2705 Mutant EGFR inhibitor

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Mutant EGFR inhibitor 是选择性EGFR 突变体抑制剂,可抑制EGFRL858R、EGFRExon 19 deletion 和EGFRT790M。
T11162 EGFR-IN-8

EGFR; c-Met/HGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
EGFR-IN-8 是 EGFR 和 c-Met 的双重抑制剂。 EGFR-IN-8可用于靶向 EGFR TKI 耐药的 NSCLC 的研究。
T11160 EGFR-IN-5

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
EGFR-IN-5 是 EGFR 的特异性抑制剂。 EGFR、EGFR(L858R)、EGFR(L858R/T790M) 和 EGFR(L858R/T790M/C797S) 的 IC50 分别为 10.4、1.1、34、7.2 nM。
T5410 PD158780

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PD158780是一种EGFR 家族抑制剂,对EGFR、ErbB2、ErbB3和ErbB4的IC50值分别为8 μM、49、52 和 52 nM。
T11569 HKI-357

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
HKI-357 是一种不可逆的 EGFR 和ERBB2双重抑制剂,IC50分别为 34 nM 和 33 nM。HKI-357 抑制 EGFR 自磷酸化 (Y1068位点),及 MAPK 和AKT 磷酸化。
T23176 PP 3

Src Angiogenesis; Tyrosine Kinase/Adaptors
PP 3 是 Src 激酶抑制剂 PP 2 的阴性对照
T7819 TAS0728

EGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
TAS0728 是一种 HER2 抑制剂,与HER2的 C805 位点共价结合,IC50值为 13 nM。它抑制 HER2、HER3 及其下游效应蛋白的磷酸化,具有抗肿瘤活性。
T6734 WZ8040

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
WZ8040 是一种新型突变选择性不可逆 EGFRT790M 抑制剂,可抑制EGFR 磷酸化。它对突变型EGFR 的活性是野生型EGFR 的100倍以上。
T17182 TX1-85-1

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
TX1-85-1 是不可逆 Her3 抑制剂,IC50值为 23 nM。它诱导 Her3 蛋白部分降解,并减弱 Her3 依赖性信号传导。它是选择性 Her3 配体,与位于 Her3 的 ATP 结合位点的 Cys721 形成共价键。
T2491 AZ-5104

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
AZ5104是 AZD 9291的活性去甲基化代谢物,是一种有效的 EGFR 抑制剂,抑制 EGFRL858R/T790M、EGFRL858R、EGFRL861Q、EGFR 和 ErbB4的 IC50值分别为1、6、1、25 和 7 nM。
T6824 EAI045

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
EAI045是突变体EGFR 的变构抑制剂,在10 μM ATP 时抑制EGFR、EGFRL858R、EGFRT790M 和 EGFRL858R/T790M 的IC50值分别为1.9、0.019、0.19 和 0.002 μM。
T16343 NRC-2694

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
NRC-2694 是表皮生长因子受体的有效拮抗剂,具抗增殖、有抗癌的活性。
T6238 WZ4002

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
WZ4002 是突变选择性 EGFR 抑制剂,对 EGFR(L858R) 和 EGFR(T790M) 的 IC50 为 2 和 8 nM。
T6733 WZ-3146

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
WZ3146是一种突变选择性EGFR 抑制剂,对EGFRL858R、EGFRL858R/T790M、EGFRE746_A750、EGFRE746_A750/T790M 和 EGFR 的IC50值分别为2、2、5、14 和 66 nM。
T10534 BI-4020

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
BI-4020 是一种第四代,口服有效,非共价的 EGFR 酪氨酸激酶抑制剂。BI-4020 表现出对三联突变的 EGFR del19 T790M C797S 突变体 ( BaF3 细胞系,IC50=0.2 nM),双重突变的 EGFR del19 T790M 以及单突变的 EGFR del19 (IC50=1 nM)的抑制剂活性。BI-4020 保留了抑制 EGFR wt 的活性 (IC50=190 nM)。BI-4020 具有高激酶组选择性和良好的 DMPK 性质。
T5437 Gefitinib-based PROTAC 3

EGFR; PROTACs Angiogenesis; JAK/STAT signaling; PROTAC; Tyrosine Kinase/Adaptors
Gefitinib-based PROTAC 3 通过 linker 将 EGFR 结合元件与 von Hippel-Lindau 配体结合,在 HCC827(外显子 19 del)和 H3255(L858R 突变)细胞中诱导 EGFR 降解,DC50 分别为 11.7 和 22.3 nM。
T9912 Trastuzumab

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Trastuzumab 是人源化单克隆抗体,以高亲和力与HER2选择性结合,可用于 HER2 阳性转移性乳腺癌和 HER2 阳性胃癌的研究。
T2034 AG1557

AG-1557,AG 1557

EGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
AG1557 (AG-1557) 是一种表皮生长因子受体(EGFR) 酪氨酸激酶抑制剂,pIC50值为 8.194。
T6092 Sapitinib

沙普替尼,AZD-8931

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Sapitinib (AZD-8931) 是可逆的 ATP 竞争型 EGFR 抑制剂,对 EGFR、ErbB2 和 ErbB3的IC50值分别为4、3 和 4 nM。
TQ0092 Naquotinib

ASP8273

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Naquotinib (ASP8273) 是一种口服的、突变体选择性和不可逆的 EGFR 抑制剂,对EGFR 突变体和EGFR 的IC50值分别为8-33和230 nM。
T6008 CNX-2006

CNX 2006,CNX2006

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
CNX-2006 是一种新型的不可逆突变选择性 EGFR 抑制剂,对 EGFRT790M 的IC50值小于 20 nM。
T3659 Zorifertinib

AZD3759

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Zorifertinib (AZD3759) 是一种可口服的中枢神经系统渗透性 EGFR 抑制剂,对 EGFRwt、EGFRL858R 和 EGFRexon 19Del,IC50分别为 0.3、0.2 和 0.2 nM。
T16369 O-Desmethyl gefitinib

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
O-Desmethyl gefitinib 是依赖于 CYP2D6 活性形成的,是 Gefitinib 在人血浆中的活性代谢产物。在亚细胞试验中,它抑制 EGFR,IC50为 36 nM。
T8431 JCN037

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
JCN037 是能透过血脑屏障的EGFR 共价抑制剂,对 EGFR、p-wtEGFR 和 pEGFRvⅢ 的IC50值分别为 2.49、3.95 和4.48 nM。
T3466 FIIN-3

EGFR; FGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
FIIN-3 是FGFR 的不可逆抑制剂,对FGFR1、FGFR2、FGFR3和FGFR4的IC50值分别为13.1、21、31.4和35.3 nM。
T11161 EGFR-IN-7

TQB3804

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
EGFR-IN-7 (TQB3804) 是一种有效选择性的EGFR 激酶抑制剂,对 EGFR (WT) 和 EGFR (mutant C797S/T790M/L858R) 的IC50值分别为 7.92 和 0.218 nM,具有抗肿瘤活性。
T13564 AZ7550

MLK; FAK; EGFR; FLT; Tyrosine Kinases; PYK2; MNK; IGF-1R; ACK; BTK; ALK; Drug Metabolite Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; Metabolism; Tyrosine Kinase/Adaptors
AZ7550 是 AZD9291 的活性代谢物,可抑制 IGF1R 活性,IC50为 1.6 μM。
T8534 Tyrphostin AG 112

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tyrphostin AG 112 是一种EGFR 磷酸化抑制剂。
T3108 CUDC-101

CUDC 101,CUDC101

EGFR; HER; HDAC Angiogenesis; Chromatin/Epigenetic; DNA Damage/DNA Repair; JAK/STAT signaling; Tyrosine Kinase/Adaptors
CUDC-101 是一种高效的EGFR、HDAC 和HER2抑制剂,对应的IC50值分别为 2.4、4.4 和 15.7 nM。
T5475 ZD-4190

EGFR; VEGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
ZD-4190 是血管内皮细胞生长因子受体 2 (VEGFR2) 和表皮生长因子受体 (EGFR) 信号传导的抑制剂,用于治疗癌症。
T9927 Panitumumab

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Panitumumab 是一种重组全人源 IgG2 单克隆抗体,可与表皮生长因子(EGFR)结合,具有抗肿瘤活性。
T22396 PF-6274484

PF 6274484

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PF-6274484 是一种EGFR 抑制剂,对于 EGFR-L858R/T790M 和 WT-EGFR 的 Ki 值分别为 0.14 和 0.18 nM。它在 H1975 肿瘤细胞和 A549 肿瘤细胞中抑制EGFR-L858R/T790M 自身磷酸化和EGFR-WT,IC50分别为6.6和 5.8 nM。
T6908 NSC 228155

NSC228155

EGFR; Epigenetic Reader Domain; DNA/RNA Synthesis; Histone Acetyltransferase Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; JAK/STAT signaling; Tyrosine Kinase/Adaptors
NSC 228155 是一种 EGFR 的激活剂,与 sEGFR 二聚化结构域 II 结合并调节 EGFR 酪氨酸磷酸化。
T6124 Mubritinib

木利替尼,TAK-165

EGFR; FGFR; JAK; PDGFR Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Mubritinib (TAK-165) 是选择性的EGFR2/HER2抑制剂,IC50值为6 nM。
T13088 Tarloxotinib bromide

TH-4000

EGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tarloxotinib bromide (TH-4000) 是一种不可逆的 EGFR/HER2 抑制剂。
T6932 PD168393

Apoptosis; EGFR; FGFR; IGF-1R; PDGFR; PKC; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PD168393 是一种细胞渗透性的选择性 EGFR 酪氨酸激酶和 ErbB2的抑制剂。它不可逆转地失活 EGF 受体,IC50值为 0.7 nM,但对胰岛素受体、PDGFR、FGFR 和 PKC 无作用。
T3024 Avitinib

AC0010,艾维替尼

EGFR; JAK; BTK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Avitinib (AC0010) 是一种不可逆的、突变体选择性的EGFR 抑制剂,可有效抑制非小细胞肺癌中EGFR T790M 耐药突变。阿比替尼也是一种新型BTK 抑制剂。
T21853 (E)-AG 556

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
(E)-AG 556 是有效的、选择性 EGFR 抑制剂。(E)-AG 556阻断 LPS 诱导的促炎因子 TNF-α 的产生。
T6039 TAK-285

TAK285,TAK 285

EGFR; MEK; HER; Aurora Kinase Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors
TAK-285 是一种新型 HER2 和 EGFR(HER1) 双重抑制剂,IC50 分别为 17 和 23 nM。它可穿过血脑屏障,有抗肿瘤活性,对 HER1/2 的选择性是 HER4 的 10 倍以上。
T3721 Avitinib maleate

艾维替尼马来酸盐,艾维替尼

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Avitinib maleate 是基于吡咯并嘧啶的不可逆的表皮生长因子受体抑制剂,IC50值为7.68 nM。
T10419 AV-412

MP412

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
AV-412 (MP412) 是一种EGFR 抑制剂,抑制EGFR、EGFRL858R、EGFRT790M、EGFRL858R/T790M 和 ErbB2 的IC50值分别为0.75、0.5、0.79、2.3 和 19 nM。
T39275 Befotertinib

D-0316,Befotertinib

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Befotertinib (D-0316) 是一种 EGFR 酪氨酸激酶抑制剂,可用于 EGFR T790M 阳性非小细胞肺癌的研究。
T8151 Mobocertinib

tak788

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Mobocertinib (tak788) 是可口服的EGFR 和HER2突变的抑制剂,具有抗肿瘤活性。
T4014 CP-724714

CP724714,CP 724714

Apoptosis; EGFR Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
CP-724714 (CP724714) 是一种高效、选择性口服活性的 ErbB2 (HER2)酪氨酸激酶抑制剂,IC50为 10 nM。它能抑制完整细胞中 ErbB2 受体的自磷酸化,具有抗肿瘤活性。它对 EGFR 激酶有明显的选择性,IC50值为6400 nM。
T16162 Mutated EGFR-IN-1

Osimertinib analog,AZD9291中间体1

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Mutated EGFR-IN-1 (Osimertinib analog) 是用于突变 EGFR 抑制剂设计的有用中间体,例如 L858R EGFR、Exon19 缺失激活突变体和 T790M 抗性突变体。
T2307 Icotinib Hydrochloride

埃克替尼盐酸盐,盐酸埃克替尼,BPI-2009H

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Icotinib Hydrochloride (BPI-2009H) 是一种口服的基于喹唑啉的表皮生长因子受体 (EGFR) 抑制剂,IC50值为5 nM,具有潜在的抗肿瘤活性。
T12594 Pyrotinib dimaleate

SHR-1258 dimaleate

EGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Pyrotinib dimaleate (SHR-1258 dimaleate) 是选择性的 EGFR/HER2双重抑制剂,IC50值分别为 13 和 38 nM。

化合物

EGFR/ErbB-2/ErbB-4 inhibitor-2
Cat.No: T21954
Synonym: EGFR/ErbB2 Inhibitor
Target: EGFR
EGFR/ErbB-2 inhibitor-1
Cat.No: T79861
Synonym:
Target: EGFR
ErbB-2-binding peptide
Cat.No: T76542
Synonym:
Target:
Mutant EGFR inhibitor
Cat.No: T2705
Synonym:
Target: EGFR
EGFR-IN-8
Cat.No: T11162
Synonym:
Target: EGFR, c-Met/HGFR
EGFR-IN-5
Cat.No: T11160
Synonym:
Target: EGFR
PD158780
Cat.No: T5410
Synonym:
Target: EGFR
HKI-357
Cat.No: T11569
Synonym:
Target: EGFR
PP 3
Cat.No: T23176
Synonym:
Target: Src
TAS0728
Cat.No: T7819
Synonym:
Target: EGFR, HER
WZ8040
Cat.No: T6734
Synonym:
Target: EGFR
TX1-85-1
Cat.No: T17182
Synonym:
Target: EGFR
AZ-5104
Cat.No: T2491
Synonym:
Target: EGFR
EAI045
Cat.No: T6824
Synonym:
Target: EGFR
NRC-2694
Cat.No: T16343
Synonym:
Target: EGFR
WZ4002
Cat.No: T6238
Synonym:
Target: EGFR
WZ-3146
Cat.No: T6733
Synonym:
Target: EGFR
BI-4020
Cat.No: T10534
Synonym:
Target: EGFR
Gefitinib-based PROTAC 3
Cat.No: T5437
Synonym:
Target: EGFR, PROTACs
Trastuzumab
Cat.No: T9912
Synonym:
Target: EGFR
AG1557
Cat.No: T2034
Synonym: AG-1557,AG 1557
Target: EGFR, HER
Sapitinib
Cat.No: T6092
Synonym: 沙普替尼,AZD-8931
Target: EGFR
Naquotinib
Cat.No: TQ0092
Synonym: ASP8273
Target: EGFR
CNX-2006
Cat.No: T6008
Synonym: CNX 2006,CNX2006
Target: EGFR
Zorifertinib
Cat.No: T3659
Synonym: AZD3759
Target: EGFR
O-Desmethyl gefitinib
Cat.No: T16369
Synonym:
Target: EGFR
JCN037
Cat.No: T8431
Synonym:
Target: EGFR
FIIN-3
Cat.No: T3466
Synonym:
Target: EGFR, FGFR
EGFR-IN-7
Cat.No: T11161
Synonym: TQB3804
Target: EGFR
AZ7550
Cat.No: T13564
Synonym:
Target: MLK, FAK, EGFR, FLT, Tyrosine Kinases, PYK2, MNK, IGF-1R, ACK, BTK, ALK, Drug Metabolite
Tyrphostin AG 112
Cat.No: T8534
Synonym:
Target: EGFR
CUDC-101
Cat.No: T3108
Synonym: CUDC 101,CUDC101
Target: EGFR, HER, HDAC
ZD-4190
Cat.No: T5475
Synonym:
Target: EGFR, VEGFR
Panitumumab
Cat.No: T9927
Synonym:
Target: EGFR
PF-6274484
Cat.No: T22396
Synonym: PF 6274484
Target: EGFR
NSC 228155
Cat.No: T6908
Synonym: NSC228155
Target: EGFR, Epigenetic Reader Domain, DNA/RNA Synthesis, Histone Acetyltransferase
Mubritinib
Cat.No: T6124
Synonym: 木利替尼,TAK-165
Target: EGFR, FGFR, JAK, PDGFR
Tarloxotinib bromide
Cat.No: T13088
Synonym: TH-4000
Target: EGFR, HER
PD168393
Cat.No: T6932
Synonym:
Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy
Avitinib
Cat.No: T3024
Synonym: AC0010,艾维替尼
Target: EGFR, JAK, BTK
(E)-AG 556
Cat.No: T21853
Synonym:
Target: EGFR
TAK-285
Cat.No: T6039
Synonym: TAK285,TAK 285
Target: EGFR, MEK, HER, Aurora Kinase
Avitinib maleate
Cat.No: T3721
Synonym: 艾维替尼马来酸盐,艾维替尼
Target: EGFR
AV-412
Cat.No: T10419
Synonym: MP412
Target: EGFR
Befotertinib
Cat.No: T39275
Synonym: D-0316,Befotertinib
Target: EGFR
Mobocertinib
Cat.No: T8151
Synonym: tak788
Target: EGFR
CP-724714
Cat.No: T4014
Synonym: CP724714,CP 724714
Target: Apoptosis, EGFR
Mutated EGFR-IN-1
Cat.No: T16162
Synonym: Osimertinib analog,AZD9291中间体1
Target: EGFR
Icotinib Hydrochloride
Cat.No: T2307
Synonym: 埃克替尼盐酸盐,盐酸埃克替尼,BPI-2009H
Target: EGFR
Pyrotinib dimaleate
Cat.No: T12594
Synonym: SHR-1258 dimaleate
Target: EGFR, HER
Cat. No. Product Name Target Signaling Pathways
T22974 Methyl 2,5-dihydroxycinnamate

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Methyl 2,5-dihydroxycinnamate 是 erbstatin 类似物,是一种高效、稳定的 EGF 受体相关酪氨酸激酶的抑制剂。
T3870 Cyasterone

杯苋甾酮,Cyasteron

Apoptosis; EGFR Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Cyasterone (Cyasteron) 是主要分离自金疮小草的一种天然 EGFR 抑制剂。它通过诱导细胞凋亡和细胞周期阻滞表现出抗增殖作用,可用于抗人类肿瘤的相关研究。
TL0016 Sulforaphene

油菜

Apoptosis; ERK; EGFR; NF-κB Angiogenesis; Apoptosis; JAK/STAT signaling; MAPK; NF-κB; Tyrosine Kinase/Adaptors
Sulforaphene 是从萝卜种子中分离出来的天然产物,对鹿茸幼苗的 ED50 约为 2 x 10 -4 M。它通过抑制 EGFR、p-ERK1/2、NF-κB 和其他信号促进癌细胞凋亡并抑制迁移。
T1431 Khellin

凯林,Amicardine,Methafrone,Visammin

EGFR; Others Angiogenesis; JAK/STAT signaling; Others; Tyrosine Kinase/Adaptors
Khellin (Methafrone) 是从阿米芹中提取得到的一种呋喃并色酮,是EGFR 抑制剂,IC50为 0.15 µM。它体外具有抗增殖活性,还具有抗痉挛和冠状动脉舒张作用。
T2995 Chrysophanol

大黄酚,3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Chrysophanol (Turkey Rhubarb) 是掌叶大黄中的一种蒽醌类天然产物,可抑制EGF-诱导的EGFR 磷酸化,且抑制AKT 和mTOR/p70S6K 激活。
T1737 Genistein

NPI 031L,三叶草,染料木素,金雀异黄酮

Apoptosis; EGFR; Endogenous Metabolite; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
Genistein (NPI 031L) 是一种大豆异黄酮,是一种多重的酪氨酸激酶抑制剂,通过改变细胞凋亡,细胞周期和血管生成以及抑制转移对多种癌症有化疗作用。
T6427 Butein

2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Apoptosis; EGFR; Others; PDE; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂,也是蛋白酪氨酸激酶抑制剂,还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路,靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
T1181 Gefitinib

ZD1839,吉非替尼

EGFR; Tyrosine Kinases; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Gefitinib (ZD1839) 是一种 EGFR 一代抑制剂,具有口服活性,抑制 EGFR 19 Del 和 L858R 突变。Gefitinib 具有抗肿瘤活性,用于治疗 EGFR 突变的非小细胞肺癌。Gefitinib 用药会产生 EGFR C797S 耐药突变。
T2851 Daphnetin

7,8-Dihydroxycoumarin,Daphnetol,瑞香素

EGFR; PKA; PKC; Parasite; Autophagy Angiogenesis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Daphnetin (7,8-Dihydroxycoumarin) 是从 Genus Daphne 中分离得到的香豆素衍生物,有抗氧化、抗炎、抗疟疾和解热作用,可用于凝血功能障碍、类风湿性关节炎等疾病的相关研究。
TN1440 Beta-Hydroxyisovalerylshikonin

EGFR; Tyrosine Kinases; Prostaglandin Receptor; Src; AMPK; Fatty Acid Synthase Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Beta-hydroxyisovalerylshikonin 是分离自Lithospermium radix 的天然产物,具有抑制PTK 的作用, 对 EGFR 和 v-Src 受体作用的IC50分别为 0.7 μM 和 1 μM。它对多种肿瘤细胞系均有抑制作用,可以高效诱导 NCI-H522 和 DMS114 细胞的死亡。
T4183 lavendustin A

RG-14355,NSC 678027,薰草菌素

EGFR; Tyrosinase Angiogenesis; JAK/STAT signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
lavendustin A (RG-14355) 是从链霉菌中分离得到的一种天然产物,是细胞渗透性表皮生长因子受体 (EGFR) 酪氨酸激酶抑制剂,能抑制血管内皮生长因子诱导的血管生成,阻断 LTPGABA-A 的诱导。

天然产物

Methyl 2,5-dihydroxycinnamate
Cat.No: T22974
Synonym:
Target: EGFR
Cyasterone
Cat.No: T3870
Synonym: 杯苋甾酮,Cyasteron
Target: Apoptosis, EGFR
Sulforaphene
Cat.No: TL0016
Synonym: 油菜
Target: Apoptosis, ERK, EGFR, NF-κB
Khellin
Cat.No: T1431
Synonym: 凯林,Amicardine,Methafrone,Visammin
Target: EGFR, Others
Chrysophanol
Cat.No: T2995
Synonym: 大黄酚,3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb
Target: EGFR
Genistein
Cat.No: T1737
Synonym: NPI 031L,三叶草,染料木素,金雀异黄酮
Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy
Butein
Cat.No: T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因
Target: Apoptosis, EGFR, Others, PDE, Autophagy
Gefitinib
Cat.No: T1181
Synonym: ZD1839,吉非替尼
Target: EGFR, Tyrosine Kinases, Autophagy
Daphnetin
Cat.No: T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol,瑞香素
Target: EGFR, PKA, PKC, Parasite, Autophagy
Beta-Hydroxyisovalerylshikonin
Cat.No: TN1440
Synonym:
Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase
lavendustin A
Cat.No: T4183
Synonym: RG-14355,NSC 678027,薰草菌素
Target: EGFR, Tyrosinase
Cat. No. Product Name Species Expression System
TMPY-02365 HER3/ERBB3 Protein, Mouse, Recombinant (His)

Erbb-3r,Erbb3r,erb-b2 receptor tyrosine ki...

Mouse HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70 kDa and the accession number is Q61526.
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant

LCCS2,c-erbB-3,HER3,p180-ErbB3,erbB

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1.
TMPY-04956 HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

MDA-BF-1,c-erbB-3,HER3,p85-sErbB3,LCCS2,p1...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
TMPY-01389 HER3/ERBB3 Protein, Human, Recombinant (His)

MDA-BF-1,EEBB3,erbB3-S,p45-sErbB3,ErbB...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
TMPY-02469 HER2/ERBB2 Protein, Mouse, Recombinant (hFc)

EGFR2,c-erbB2,l11Jus8,Erbb-2,mKIAA3023,Neu...

Mouse HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.7 kDa and the accession number is P70424.
TMPY-02314 HER2/ERBB2 Protein, Mouse, Recombinant (His)

HER2,c-erbB2,erb-b2 receptor tyrosine kinase 2,Neu,...

Mouse HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is P70424.
TMPJ-00778 HER2/ERBB2 Protein, Human, Recombinant (His)

TKR1,Metastatic lymph node gene 19 protein,ERBB2,Pr...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPY-00742 EGFR Protein, Human, Recombinant (His)

mENA,NISBD2,ERBB1,HER1,PIG61,ERBB,epiderma...

Human HEK293 Cells
EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-04529 EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)

epidermal growth factor receptor,PIG61,ERBB1,NISBD2...

Human Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPY-02676 EGFR Protein, Mouse, Recombinant (His)

Errp,AI552599,Errb1,9030024J15Rik,wa2,Erbb,wa-2,Wa5...

Mouse HEK293 Cells
EGFR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is Q01279.
TMPY-06658 HER3/ERBB3 Protein, Mouse, Recombinant (hFc)

Erbb3,C76256,Erbb-3,erb-b2 receptor tyrosi...

Mouse HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.23 kDa and the accession number is Q61526.
TMPY-03021 ErbB4 Protein, Mouse, Recombinant (His)

c-erbB-4,Her4,erb-b2 receptor tyrosine kinase 4

Mouse HEK293 Cells
ErbB4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.5 kDa and the accession number is Q99P91.
TMPY-06659 HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated

C76256,Her3,Erbb-3,Erbb3,Erbb3r,<...

Mouse HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.76 kDa and the accession number is Q61526.
TMPK-00453 HER3/ERBB3 Protein, Human, Recombinant (His & Avi)

p45-sErbB3,MDA-BF-1,ErbB-3,HER3c-erbB<...

Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.
TMPK-01280 HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

p85-sErbB3,HER3,LCCS2,p180-ErbB3,HER3c-

Cynomolgus,Rhesus HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number i...
TMPK-00452 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled

LCCS2,HER3c-erbB-3,p180-ErbB3,MGC88033,

Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession numbe...
TMPJ-00791 HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)

p185erbB2,Epidermal growth factor receptor-related ...

Rat E. coli
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB...
TMPY-00795 HER3/ERBB3 Protein, Human, Recombinant (hFc)

HER3,c-erbB-3,p180-ErbB3,ErbB-3,p...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
TMPY-05753 HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated

HER3,p180-ErbB3,MDA-BF-1,erbB3-S,p85-s...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
TMPY-03761 HER3/ERBB3 Protein, Human, Recombinant (mFc)

c-erbB-3,c-erbB3,HER3,erb-b2 receptor tyro...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 95 kDa and the accession number is P21860-1.
TMPY-06631 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated

c-erbB3,MDA-BF-1,ErbB-3,erbB3-S,c...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.93 kDa and the accession number is NP_001973.2.
TMPY-04541 HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST)

c-erbB3,ErbB-3,p45-sErbB3,LCCS2,p...

Human Baculovirus Insect Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65 kDa and the accession number is P21860-1.
TMPJ-00413 HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated

Proto-oncogene-like protein c-ErbB-3,HER3,ERBB<...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 90-120 KDa and the accession number is P21860.
TMPJ-00899 HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)

HER3,Proto-oncogene-like protein c-ErbB-3,ERBB<...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.
TMPJ-00648 EGFR vIII Protein, Human, Recombinant (His)

EGFR,Proto-oncogene c-ErbB-1,Epidermal growth facto...

Human HEK293 Cells
EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 61-75 Kda and the accession number is NP_001333870.
TMPJ-00776 HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Tyrosine kinase-type cell surface receptor HER2,NGL,EGFR2,TK...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-140 KDa and the accession number is P04626.
TMPJ-00647 EGFR vIII Protein, Human, Recombinant (hFc)

EGFR,Epidermal growth factor receptor,Proto-oncogene c-E...

Human HEK293 Cells
EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is NP_001333870.
TMPJ-00646 EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated

Epidermal growth factor receptor,EGFR,Proto-oncogene c-E...

Human HEK293 Cells
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is NP_001333870.
TMPJ-00777 HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)

TKR1,Proto-oncogene Neu,EGFR2,Tyrosine kinase-type cell surf...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and the accession number is P04626.
TMPY-06549 EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)

ERBB,epidermal growth factor receptor,HER1,mENA,

Human HEK293 Cells
EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.09 kDa and the accession number is NP_001333870.1.
TMPY-05612 EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated

mENA,PIG61,HER1,ERBB1,ERBB,NISBD2,epiderma...

Human HEK293 Cells
EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.9 kDa and the accession number is P00533-1.
TMPY-05258 EGFR Protein, Human, Recombinant (Isoform Viii, hFc)

NISBD2,epidermal growth factor receptor,ERBB,PIG61,...

Human Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (Isoform Viii, hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession number is NP_001333870.1.
TMPY-05211 EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)

NISBD2,PIG61,ERBB,mENA,epidermal growth factor rece...

Human Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is NP_001333870.1.
TMPY-01043 EGFR Protein, Human, Recombinant (hFc)

ERBB,mENA,HER1,ERBB1,PIG61,NISBD2,epiderma...

Human HEK293 Cells
EGFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95 kDa and the accession number is P00533-1.
TMPY-05637 EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated

epidermal growth factor receptor,HER1,mENA,ERBB1,

Human Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 41.8 kDa and the accession number is NP_001333870.1.
TMPY-06593 EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated

PIG61,ERBB1,ERBB,NISBD2,epidermal growth f...

Human HEK293 Cells
EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.90 kDa and the accession number is NP_001333870.1.
TMPK-00692 EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated

EC 2.7.10.1,PIG61,NISBD2,HER1,mENA,LEGFR,ErbB,EC 2....

Human HEK293 Cells
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated is exp...
TMPK-00691 EGFRVIII Protein, Human, Recombinant (His & Avi)

EGFR,ErbB,mENA,HER1,LEGFR,EC 2.7.10.1,PIG61,EC 2.7....

Human HEK293 Cells
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi) is expressed in HEK2...
TMPK-00425 EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled

EC 2.7.10.1,HER1,EGFR,PIG61,LEGFR,ErbB,ERBB

Human HEK293 Cells
EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPK-00426 EGFR Protein, Human, Recombinant (His & Avi)

PIG61,mENA,NISBD2,EC 2.7.10.1,HER1,EC 2.7.10,ERBB1,...

Human HEK293 Cells
EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPK-00689 EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled

EC 2.7.10.1,EC 2.7.10,ERBB1,EGFR,mENA,NISBD2,HER1,<...

Human HEK293 Cells
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled is expre...
TMPK-00427 EGFR Protein, Human, Recombinant (His & Avi), Biotinylated

PIG61,ERBB,LEGFR,mENA,EC 2.7.10.1,EGFR,EC 2.7.10,

Human HEK293 Cells
EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPK-00902 EGFR Protein, Rhesus macaque, Recombinant (His)

HER1,EC 2.7.10,EGFR,NISBD2,ErbB,PIG61,ERBB...

Rhesus HEK293 Cells
EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.8 kDa and the accession number is P55245.
TMPK-00690 EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled

LEGFR,ERBB1,EGFR,HER1,PIG61,NISBD2,EC 2.7.10,ER...

Human HEK293 Cells
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled is exp...
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-02675 EGFR Protein, Mouse, Recombinant (hFc)

Erbb,AI552599,wa-2,9030024J15Rik,Errp,wa2,Errb1,Wa5...

Mouse HEK293 Cells
EGFR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96 kDa and the accession number is Q01279.
TMPY-00246 HER3/ERBB3 Protein, Rhesus, Recombinant

erb-b2 receptor tyrosine kinase 3

Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.5 kDa and the accession number is XP_001113953.2.
TMPY-01944 HER2/ERBB2 Protein, Rat, Recombinant (His)

EGFR2,erb-b2 receptor tyrosine kinase 2

Rat HEK293 Cells
HER2/ERBB2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.2 kDa and the accession number is AAH61863.1.
TMPY-00636 HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)

erb-b2 receptor tyrosine kinase 2,EGFR2

Cynomolgus HEK293 Cells
HER2/ERBB2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is G7PUM4.
TMPY-02477 HER3/ERBB3 Protein, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 3

Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.1 kDa and the accession number is XP_005571238.1&XP_001113953.2.
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重组蛋白

HER3/ERBB3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02365
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant
Cat.No: TMPY-00399
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04956
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01389
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02469
Species: Mouse
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02314
Species: Mouse
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00778
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (His)
Cat.No: TMPY-00742
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)
Cat.No: TMPY-04529
Species: Human
Expression System: Baculovirus Insect Cells
EGFR Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02676
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-06658
Species: Mouse
Expression System: HEK293 Cells
ErbB4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03021
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06659
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00453
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-01280
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00452
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
Cat.No: TMPJ-00791
Species: Rat
Expression System: E. coli
HER3/ERBB3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00795
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05753
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03761
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06631
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST)
Cat.No: TMPY-04541
Species: Human
Expression System: Baculovirus Insect Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated
Cat.No: TMPJ-00413
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
Cat.No: TMPJ-00899
Species: Human
Expression System: HEK293 Cells
EGFR vIII Protein, Human, Recombinant (His)
Cat.No: TMPJ-00648
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPJ-00776
Species: Human
Expression System: HEK293 Cells
EGFR vIII Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00647
Species: Human
Expression System: HEK293 Cells
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00646
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
Cat.No: TMPJ-00777
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)
Cat.No: TMPY-06549
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated
Cat.No: TMPY-05612
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (Isoform Viii, hFc)
Cat.No: TMPY-05258
Species: Human
Expression System: Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)
Cat.No: TMPY-05211
Species: Human
Expression System: Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01043
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated
Cat.No: TMPY-05637
Species: Human
Expression System: Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated
Cat.No: TMPY-06593
Species: Human
Expression System: HEK293 Cells
EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00692
Species: Human
Expression System: HEK293 Cells
EGFRVIII Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00691
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00425
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00426
Species: Human
Expression System: HEK293 Cells
EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
Cat.No: TMPK-00689
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00427
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00902
Species: Rhesus
Expression System: HEK293 Cells
EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00690
Species: Human
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
EGFR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02675
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant
Cat.No: TMPY-00246
Species: Rhesus
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Rat, Recombinant (His)
Cat.No: TMPY-01944
Species: Rat
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-00636
Species: Cynomolgus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-02477
Species: Rhesus
Expression System: HEK293 Cells
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