102
44
49
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3207 |
Briciclib
ON 014185 |
CDK; PERK; Autophagy | Apoptosis; Autophagy; Cell Cycle/Checkpoint |
Briciclib (ON 014185) 是一种 ON 013100 衍生物,是一种抑制 Y 细胞中 cyclin D1 积累的小分子。它可靶作用于eIF4E,有抑制实体瘤的潜力。 | |||
TP1143L |
Fibrinopeptide A, human acetate
Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate |
Others | Others |
Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate)(25422-31-5 free base) 是一种 16 个残基的短多肽,由凝血酶从纤维蛋白原上切割下来。纤维蛋白肽 A (FPA) 由纤维蛋白原蛋白的 N 末端 Aα 区域在被凝血酶切割后产生。 | |||
T1655 |
Ambrisentan
BSF-208075,BSF 208075,安倍生坦,LU 208075 |
Endothelin Receptor | GPCR/G Protein |
Ambrisentan (BSF 208075) 是 ET A 型受体选择性拮抗剂。 | |||
T2711 |
Chembridge-5861528
TCS 5861528 |
TRP/TRPV Channel | Membrane transporter/Ion channel |
Chembridge-5861528 (TCS 5861528) 是有效的 TRPA1离子通道阻断剂。 | |||
T6036 |
Brivanib
BMS-540215,布立尼布 |
EGFR; VEGFR; FGFR; Autophagy | Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Brivanib (BMS-540215) 是一种针对 VEGFR2 的 ATP 竞争性抑制剂,IC50 为 25 nM。它对 VEGFR-1 和 FGFR-1 具有中等效力,对 VEGFR2 的选择性是对 PDGFR-β 的 240 倍。 | |||
T7143 |
Alagebrium chloride
4,5-二甲基-3-(2-氧代-2-苯基乙基)噻唑氯化物,ALT711,阿拉氯胺 |
Others; Endogenous Metabolite | Metabolism; Others |
Alagebrium chloride (ALT711) 是晚期糖基化终产物(AGE) 抑制剂。 | |||
T0718 |
Brivudine
Bromovinyldeoxyuridine,BVDU,溴夫定 |
Others; HSV | Microbiology/Virology; Others |
Brivudine (BVDU) 是胸苷类似物,有抗病毒活性,用于早期急性带状疱疹的研究。 | |||
T2576 |
Brivanib (alaninate)
丙氨酸布立尼布,BMS-582664,Brivanib Alaninate |
VEGFR; FGFR; Autophagy | Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors |
Brivanib Alaninate (BMS-582664) 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐,IC50值为 25 nM,具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制,对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。 | |||
T6124 |
Mubritinib
木利替尼,TAK-165 |
EGFR; FGFR; JAK; PDGFR | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Mubritinib (TAK-165) 是选择性的EGFR2/HER2抑制剂,IC50值为6 nM。 | |||
T5118 |
Brilanestrant
GDC0810,GDC 0810,GDC-0810,ARN-810,RG 6046 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Brilanestrant (GDC-0810) 是一种雌激素选择性降能器 (selective estrogen receptor degrader)(IC50:0.7 nM),口服具有活性。 | |||
T11179 |
Elubrixin
SB-656933 |
IL Receptor; CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
Elubrixin (SB-656933) 是一种有效和特异性的 CXCR2 和 IL-8 受体拮抗剂。 Elubrixin 可用于炎症性疾病的研究,例如炎症性肠病和气道炎症。 | |||
T50003 |
Debrisoquin hydriodide
1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide |
Others | Others |
Debrisoquin hydriodide (1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide) 具有抗氧化、抗炎和神经保护特性,也被发现可以调节某些神经递质的活性,包括多巴胺和血清素,使其成为治疗帕金森病和抑郁症等神经疾病的有前途的候选药物。 | |||
TP1736L |
Fibrinogen-Binding Peptide 137235-80-4(fb-acetate)
|
Others | Others |
Fibrinogen-Binding Peptide 137235-80-4(fb-acetate) 是纤维蛋白原受体上玻连蛋白结合位点的推定肽模拟物。它结合纤维蛋白原并抑制血小板与纤维蛋白原的粘附和血小板聚集,还抑制血小板与玻连蛋白的粘附 | |||
T22280 |
BRITE-338733
BRITE338733 |
ATPase; Antibacterial | Membrane transporter/Ion channel; Microbiology/Virology |
BRITE-338733 是一种新型ATPase 抑制剂,抑制 RecA 在细菌中的表达,IC50 值为 4.7 µM,用于治疗细菌感染。 | |||
T61268 |
Vutiglabridin
HSG4112 |
Phosphatase | Metabolism |
Vutiglabridin (HSG4112) 是一种新型且安全的PON2调节剂,是一个外消旋化合物。Vutiglabridin 是Glabridin 的优化结构类似物,比Glabridin 在减重效果和化学稳定性方面更加优越。Vutiglabridin 通过靶向线粒体对氧磷酶-2改善mptp 诱导的帕金森病小鼠的神经变性。Vutiglabridin 是一种治疗肥胖的临床2期药物,在PD 模型中对对线粒体PON2具有治疗作用。Vutiglabridin 渗透到大脑,结合PON2,恢复1-甲基-4-苯基吡啶(MPP*)诱导的SH-SY5Y 神经母细胞瘤细胞线粒体功能障碍。Vutiglabridin 在小鼠实验中 显著减轻了1-甲基-4苯基-1,2,3,6-四氢吡啶(MPTP)诱导的PD 模型小鼠的运动障碍和多巴胺能神经元损伤。 | |||
T14782 |
Brilaroxazine
RP5063 |
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
Brilaroxazine (RP5063) 是一种有效的多模式多巴胺/5-HT 调节剂。 Brilaroxazine 是多巴胺 D2、D3 和 D4 受体、5-HT1A (Ki = 1.5 nM) 和 5-HT2A (Ki = 2.5 nM) 的部分激动剂,具有拮抗活性 5-HT2B 和 5-HT7 受体,Ki 分别为 0.19 nM 和 2.7 nM。 Brilaroxazine 可用于研究神经精神和神经系统疾病的认知障碍。 | |||
T20731 |
Brilliant blue G-250
酸性蓝 90,BBG,Acid blue 90, Coomassie Brilliant Blue G,Brilliant Blue G |
P2X Receptor | Membrane transporter/Ion channel; Neuroscience |
Brilliant blue G-250 (Acid blue 90, Coomassie Brilliant Blue G) 是一种可视化的染料,常用于 SDS-PAGE 分离蛋白质,染色过程简单,定量高。在 Bradford 蛋白质分析中,它能够与蛋白质结合,通过595 nm 处的吸光度确定蛋白质浓度。它也是一种安全的 P2×7R 选择性拮抗剂,有望使 NLRP3炎症体失活。 | |||
T7771 |
Brilliant Blue FCF
FD&C Blue No. 1,Erioglaucine disodium salt,Acid Blue 9,E133,食用色素亮蓝 |
Others | Others |
Brilliant Blue FCF (Erioglaucine disodium salt) 是一种从石油中生产的合成染料,是一种芳香族烃类,用于食品和其它物质的着色剂,溶液最大吸收在628 nm。 | |||
T3045 |
Salubrinal
|
Apoptosis; Phosphatase; PERK; Autophagy; HSV | Apoptosis; Autophagy; Metabolism; Microbiology/Virology |
Salubrinal 是一种磷酸酶抑制剂 ,对真核翻译起始因子 2 亚基 (eIF2α) 发挥作用。它作为双特异性磷酸酶 2 抑制剂,抑制抗胶原蛋白抗体诱导的关节炎。它具有抗HSV-1病毒的活性,并抑制由HSV-1蛋白 ICP34.5 介导的eIF2α的去磷酸化。 | |||
T18928 |
Brilliant Black BN
亮黑1,E 151 |
Others; Virus Protease | Microbiology/Virology; Others |
Brilliant Black BN (E 151) 是一种偶氮染料和一种食品着色剂。它抑制 EV71 与其细胞脱壳因子亲环蛋白 A 之间的相互作用,是一种很有前途的抗 EV71 感染的抗病毒药物。 | |||
T3621 |
Brigatinib
布格替尼,AP-26113 |
EGFR; FLT; ROS; IGF-1R; ALK | Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Brigatinib (AP-26113) 是一种有效,选择性的ALK 抑制剂 (IC50:0.6 nM)。 | |||
T78234 |
Brilliant Yellow
Direct Yellow 4 |
transporter | Metabolism |
Brilliant Yellow (Direct Yellow 4) 是一种具有有效性和选择性的的 VGLUT 抑制剂,是一种染料,可被光降解。 | |||
T1402 |
Fenofibric acid
非诺贝特酸,Trilipix,FNF acid,NSC 281318 |
MMP; COX; PPAR | DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome |
Fenofibric acid (FNF acid) 是 fenofibrate 的活性代谢物,是PPAR 激动剂,对 PPARα、PPARγ 和 PPARδ 的EC50值分别为 22.4、1.47 和 1.06 µM。它抑制COX-2的活性,IC50值为 48 nM。 | |||
T0061 |
Clofibric acid
Chlorofibrinic acid,氯贝酸 |
PPAR; Drug Metabolite | DNA Damage/DNA Repair; Metabolism |
Clofibric acid (Chlorofibrinic acid) 是一种脂质纤维调节剂 Clofibrate,Etofibrate 和 Etofyllinclofibrate 的活性代谢物,是 PPARα的激动剂,具有降血脂作用,也可作为除草剂。 | |||
T6422 |
Brimonidine Tartrate
AGN190342 tartrate,304 tartrate,酒石酸溴莫尼定,AGN190342 (tartrate),UK 14304 (tartrate),UK14304 tartrate |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Brimonidine Tartrate (AGN190342 tartrate) 是一种 alpha2 Adrenergic Receptor (alpha2-AR) 受体激动剂。 | |||
TQ0095 |
Brincidofovir
CMX001,HDP-CDV |
Others; Antiviral; HSV | Immunology/Inflammation; Microbiology/Virology; Others |
Brincidofovir (HDP-CDV) 是 Cidofovir 的一种具有口服活性的亲脂性形式的前体药物,是一种口服长效的抗病毒药物,有广泛的抗 DNA 病毒活性。 | |||
T20157 |
Brimonidine
AGN190342,溴莫尼定,Bromoxidine,AGN 190342,AGN-190342 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Brimonidine (Bromoxidine) 是一种完全的α2肾上腺素受体激动剂。 | |||
T0142 |
Brinzolamide
布林佐胺,AL-4862 |
Carbonic Anhydrase | Metabolism |
Brinzolamide (AL-4862) 是一种碳酸酐酶(carbonic anhydrase)II 抑制剂(IC50:3.19 nM)。 | |||
T37403 | O-desmethyl Brinzolamide (hydrochloride) | ||
O-desmethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1,2It inhibits CAII and CAIV (IC50s = 0.136 and 165 nM, respectively).1 1.Huang, Q., Rui, E.Y., Cobbs, M., et al.Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressureJ. Med. Chem.58(6)2821-2833(2015) 2.Lo Faro, A.F., Tini, A., Gottardi, M., et al.Development and validation of a fast ultra-high-performance liquid chromatography tand... | |||
T31272 |
Debrisoquin sulfate
Tendor,Isocaramidine,Debrisochinum,Debrisoquine,Debrisoquin,Debrisoquina |
||
Debrisoquine is an antihypertensive drug similar to guanethidine. | |||
T123932 | Rubrisandrin A | ||
Rubrisandrin A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T123932。 | |||
T27255 |
Elubrixin HCl
SB656933,SB-656933AAF,SB-656933-AAF,SB 656933,SB-656933 AAF,SB-656933 |
||
Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist. | |||
T77189 | Sudubrilimab | ||
Sudubrilimab (HS636) 是一种针对 PDL1的 Ig G1-kappa 单克隆抗体。Sudubrilimab 在重链的 C 末端与 TGF-β1受体 Ⅱ 胞外域 (TGFBR2-ECD) 融合,可在免疫抑制性肿瘤微环境中隔离 PD-1/PD-L1通路和 TGF-β 生物活性。 | |||
T75331 |
Brilliant green
|
||
Brilliant green, a cationic dye, is utilized for coloring silk and wool. Additionally, it halts the propagation of mold, intestinal parasites, and fungus, proving effective against Gram-positive bacteria [1] [2]. | |||
T20752 |
Biebrich scarlet
NSC-79710,NSC79710,NSC 79710 |
||
Biebrich scarlet is a scarlet dye, it has been used in Masson’s trichrome stain for the staining of collagen. It has also been used for the staining of eosinophil. | |||
T80193 |
Enterocin Hybrid 1
K1-EJ hybrid |
||
Enterocin Hybrid 1为抗菌剂,具有抗菌组合物特性,能抑制对万古霉素具耐药性的大肠杆菌、粪肠球菌及溶血葡萄球菌。 | |||
T28427 |
Plafibride
|
||
Plafibride is an antiplatelet and antilipidemic agent. | |||
T131021 |
Citreohybridonol
|
||
Citreohybridonol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131021。 | |||
T30977 |
Clofibride
|
||
Clofibrin is a kind of hypolipidemic drug, which can reduce Hypertriglyceride and hypercholesterolemia. | |||
T129680 |
Hellebrigenin-3-O-?-glucoside
|
||
Hellebrigenin-3-O-?-glucoside 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T129680。 | |||
T10931 |
d-Atabrine dihydrochloride
|
Others | Others |
d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity. | |||
T80682 |
γ-Fibrinogen 377-395 TFA
|
||
γ-Fibrinogen377-395 TFA 是纤维蛋白原衍生抑制肽,具有纤维蛋白原表位特性。该化合物能在体外抑制小胶质细胞激活、阻断纤维蛋白与Mac-1相互作用,并在小鼠体内抑制实验性自身免疫性脑脊髓炎(EAE)。该肽适用于多发性硬化症(MS)及其他血脑屏障损伤和小胶质细胞激活相关的神经炎症疾病研究。 | |||
T29025 |
Tylocrebrine
NSC-60387,NSC60387,NSC 60387,Tylocrebrinel |
||
Tylocrebrine is anticancer agent. | |||
T35713 | N-desethyl Brinzolamide (oxalate) | ||
N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1It inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively). 1.Kim, C.-Y., Whittington, D.A., Chang, J.S., et al.Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IVJ. Med. Chem.45(4)888-893(2002) | |||
T32853 |
Lombricine
L-Lombricine |
||
Lombricine, as a phosphodiester of 2-guanidinoethanol and D-serine in structure, is a phosphagen that is unique to earthworms. | |||
TP1143 |
Fibrinopeptide A, human
Human fibrinopeptide A |
||
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen protein, on cleavage by thrombin. | |||
T27982 |
MBRI-001
MBRI 001,MBRI001. BPI-2358-d,plinabulin-d,NPI-2358-d |
||
MBRI-001 is a deuterium-substituted plinabulin derivative and a potent anti-cancer agent with better pharmacokinetic characteristics tand lower toxicity. | |||
T41121 |
Elubrixin tosylate
SB-656933 tosylate,Elubrixin tosylate |
||
Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b (with an IC50 of 260.7 nM) and shape change (with an IC50 of 310.5 nM). This compound holds promise for the study of inflammatory diseases, including inflammatory bowel disease and airway inflammation. | |||
T128908 |
Abrisaponin D1
|
||
Abrisaponin D1 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T128908。 | |||
T34450 |
Rumbrin
|
||
Rumbrin is a cytoprotective compound produced by Auxarthron umbrinum. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5793 |
Britannin
|
Apoptosis; AMPK; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Britannin 是分离于旋覆花的一种倍半萜内酯,可通过激活由 ROS 调节的 AMPK 来诱导肝癌细胞凋亡和自噬,具有抗增殖和抗炎活性。 | |||
T2S1682 |
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside |
Amylase | Metabolism |
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside 可抑制 α-淀粉酶活性,IC50值为0.03 umol/ml。 | |||
T2992 |
Pinocembrin
乔松素,5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone,松属素 |
NF-κB; Reactive Oxygen Species; Antibacterial; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Pinocembrin (5,7-Dihydroxyflavanone) 是从蜂胶中得到的黄酮类物质,是一种竞争性组氨酸脱羧酶抑制剂,也是抗过敏剂,具有抗氧化、抗菌、抗炎的作用。 | |||
TN2078 |
Pinocembrin chalcone
2',4',6'-Trihydroxychalcone,Pinocembrinchalcone |
Calcium Channel; Tyrosinase; Antibacterial; Antifection | Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome |
Pinocembrin chalcone 是一种具有抗诱变作用的酪氨酸酶抑制剂。 Pinocembrin 查尔酮可用于预防胃溃疡的研究。 | |||
TQ0118 |
Britannilactone
Desacetylinulicin |
Others | Others |
Britannilactone (Desacetylinulicin) 是来自 Inula britannica 的倍半萜烯,具有抗炎抗肿瘤活性。Britannilactone 与这种抗黑色素活性有关,可用于研究皮肤美白。 | |||
TN1143 |
1-O-Acetyl britannilactone
|
Apoptosis; Antibiotic | Apoptosis; Microbiology/Virology |
1-O-Acetyl britannilactone 是一种农用杀菌剂,可诱导细胞凋亡,可用于研究肝损伤和癌症。 | |||
TN1012L |
Febrifugine dihydrochloride
ISF-2123,Propyldazine hydrochloride,Atensil,(+)-Febrifugine dihydrochloride,常山乙素二盐酸盐,Pildralazine dihydrochloride |
Parasite | Microbiology/Virology |
Febrifugine dihydrochloride (Propyldazine hydrochloride) 是存在于常山的根和叶中的一种喹唑啉酮类生物碱,具有治疗疟疾、癌症、纤维化和炎症性疾病的活性。 | |||
T5710 |
Pinocembrin-7-O-β-D-glucopyranoside
Pinocembrin 7-O-beta-D-glucoside,乔松素7-O-Β-D葡萄糖苷,乔松苷 |
Others | Others |
Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-beta-D-glucoside) 是黄酮类化合物,能够提高脂质过氧化。 | |||
T3403 |
Glabridin
光甘草定,Q-100692,KB-289522,LS-176045 |
Reactive Oxygen Species; Tyrosinase; GABA Receptor; Antibacterial; PPAR | DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome |
Glabridin (KB-289522) 能够结合并激活PPARγ,EC50值为 6115 nM,是一种从Glycyrrhiza glabra 中分到的异黄烷类天然产物。它具有抗炎、抗菌、抗肾炎、抗氧化、抗肿瘤、抗糖尿病、抗骨质疏松、保护神经、保护心血管、清除自由基等作用。 | |||
TN1145 |
Isofebrifugine
|
Parasite | Microbiology/Virology |
Isofebrifugine 是一种来自虎耳草科植物常山的生物碱,具有抗疟抗感染活性。 | |||
T13693 |
Fibrin
|
Others | Others |
Fibrin 是血凝块的主要成分,为一种不溶性蛋白质,对凝血过程至关重要。这种蛋白质从牛血中分离出来,特别是在出血时合成。 | |||
TN2077 |
(+/-)-Pinocembrin
NSC 43318,(±)-5,7-Dihydroxyflavanone |
GPR; Others | Endocrinology/Hormones; GPCR/G Protein; Others |
(+/-)-Pinocembrin (NSC-43318) 是一种来自腋松的天然产物,它是一种 GPR120 配体,能促进 HaCaT 细胞系的伤口愈合。 | |||
T5718 |
L-(+)-Abrine
L-(+)-红豆碱,L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE |
Others | Others |
L-(+)-Abrine (L-N-Methyltryptophan) 是一种致命白蛋白,发现于在 Abrus precatorius 种子中,是一种急性毒性生物碱,可用作化学标记物。 | |||
TN4250 | Imbricatolic acid | p53 | Apoptosis |
Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells. | |||
TN5787 |
Imbricatin
|
||
Imbricatin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5787,CAS号为 84504-71-2。 | |||
TN5509 |
(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside
(2S)-Pinocembrin 7-O-[cinnamoyl(1→5)-β-D-apiosyl(1→2)]-β-D-glucoside |
||
(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5509,CAS号为 773899-29-9。 | |||
TN1728 |
Hellebrigenin
|
PARP; Akt; CDK | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Hellebrigenin exhibites moderate to strong activity against human HL-60, SF-295, MDA-MB-435, and HCT-8 cancer cell strains without hemolysis of mouse erythrocytes. | |||
T75554 | 6-O-Isobutyrylbritannilactone | ||
6-O-Isobutyrylbritannilactone 是一种天然的黑素生成抑制剂。6-O-Isobutyrylbritannilactone 是一种倍半萜,可从英菊花中分离得到。6-O-Isobutyrylbritannilactone 抑制 IBMX 诱导 B16F10 细胞产生黑色素。6-O-Isobutyrylbritannilactone 也调控 ERK、PI3K/AKT 和 CREB,在斑马鱼胚胎模型中显示出抗黑色素原活性。 | |||
TN2555 |
1-O-Acetyl-6-O-isobutyrylbritannilactone
|
Others | Others |
1-O-Acetyl-6-O-isobutyrylbritannilactone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2555,CAS号为 1613152-34-3。 | |||
TN4231 |
Hybridaphniphylline A
|
Others | Others |
Hybridaphniphylline A is a natural product from Daphniphyllum longeracemosum. | |||
T74202 |
Hispaglabridin A
|
||
Hispaglabridin A 是一种抗氧化剂,可有效防止脂质过氧化。 | |||
TN2511 |
Britannilactone diacetate
1,6-O,O-Diacetylbritannilactone |
IL Receptor; PARP; ROS; MAPK; Caspase; JAK; JNK; STAT | Angiogenesis; Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; JAK/STAT signaling; MAPK; Proteases/Proteasome; Stem Cells |
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 pro | |||
TN3843 |
Dibritannilactone B
|
Others | Others |
Dibritannilactone B is a natural product from Inula britannica. | |||
T81248 |
Rubriflorin B
|
||
Rubriflorin B为木脂素类化合物,原自Schisandra rubriflora分离得到。 | |||
T83371 |
3,4-Didehydroglabridin
|
||
3,4-Didehydroglabridin 是甘草中的天然产物,具有对四氯化碳诱导的 HepG2 细胞损伤的保护作用,展现出在肝损伤研究中的应用潜力。 | |||
TN4792 | Pinocembrin diacetate | Others | Others |
Pinocembrin diacetate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4792,CAS号为 111441-88-4。 | |||
TN4232 | Hybridaphniphylline B | Others | Others |
Hybridaphniphylline B is a natural product from Daphniphyllum longeracemosum. | |||
TN6135 |
Methoxyimbricatin
|
||
Methoxyimbricatin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6135,CAS号为 233759-30-3。 | |||
T74201 |
3′-Hydroxy-4′-O-methylglabridin
|
||
3′-Hydroxy-4′-O-methylglabridin 是一种抗氧化剂,可有效防止 NADH 依赖的过氧化。 | |||
TN4791 |
Pinocembrin 7-acetate
|
Others | Others |
Pinocembrin 7-acetate has antitumor activity. | |||
T73857 |
Mesembrine
|
||
Mesembrine ((+)-Mesembrine) 一种主要的生物碱,具有芳基八氢吲哚骨架。Mesembrine 是一种5-HT 转运蛋白抑制剂,Ki 为 1.4 nM。Mesembrine 还抑制磷酸二酯酶 4B (PDE4B),IC50为 7.8 μM。 | |||
TN5304 |
Desglucohellebrin
Deglucohellebrin |
||
Desglucohellebrin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5304,CAS号为 20300-44-1。 | |||
T34440 | Rubricauloside | ||
Rubricauloside is a coumarin-glycoside extracted from the roots of Peucedanum rubricaule Shan et Shch. | |||
T28019 |
(-)-Mesembrine
Mesembrin,Mesembrine,Mesembranone |
||
Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4). | |||
T24225 |
Julibrine I
|
||
Julibrine I is a bioactive chemical. | |||
TN2556 |
1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone
|
Others | Others |
1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2556,CAS号为 1932687-71-2。 | |||
TN6800 |
Colubrinic acid
|
||
Colubrinic acid is a natural product. | |||
T83379 |
2-Hydroxypinocembrin
|
||
2-Hydroxypinocembrin 是一种具有 C-糖基转移酶活性的2-羟基黄烷酮类黄酮底物。 | |||
T72742 |
(-)-Pinocembrin
(-)-乔松素 |
||
(-)-Pinocembrin 对 H37Ra 结核分枝杆菌展示了抗菌活性,无论是休眠还是活跃期,其 IC50 值分别为1.11 mg/mL 和 1.21 mg/mL。作为一种抗增殖剂,(-)-Pinocembrin 对于 THP-1、A549、Panc-1、HeLa 和 MCF7 细胞系,IC50 值范围为 1.88 至 11.00 mg/mL。 | |||
T75684 | Monascorubrin | ||
Monascorubrin 是一种从红曲菌菌丝体中纯化获得的化合物,对枯草芽孢杆菌和拟假丝酵母显示出显著的抗生素活性。 | |||
T24226 |
Julibrine II
|
||
Julibrine II is a bioactive chemical. It also exhibits arrhythmic-inducing action. | |||
TN1729 |
Hellebrigenol
|
Others | Others |
Hellebrigenol 是从越南蟾蜍毒液中提取的丁二烯内酯 ,具有抗肿瘤活性。 | |||
T82058 |
Inubritannolide A
|
||
Inubritannolide A展示了对由多种诱导剂引起的神经细胞损伤具有微弱的保护作用,这些诱导剂包括H2O2、6-羟基多巴胺(6-OHDA)和脂多糖(LPS)。 | |||
TN1012 |
Febrifugine
|
IL Receptor; Anti-infection; Parasite | Immunology/Inflammation; Microbiology/Virology |
Febrifugine 是存在于常山的根和叶中的一种喹唑啉酮类生物碱,有抗疟活性。它是一种有效的抗球虫药,具有杀灭裂殖体的作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01398 |
ITM2B Protein, Human, Recombinant (His)
Transmembrane Protein BRI,Protein E25B,BRI... |
Human | HEK293 Cells |
Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervou... | |||
TMPK-00305 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,tβR-I,TGF-... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. | |||
TMPK-00306 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFbetaRI,TGFBR1,ALK-5,SKR4,LDS2A,TGFB1R1,LDS1A,AAT5,tbetaR-... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is... | |||
TMPJ-01178 |
TGFBR1 Protein, Mouse, Recombinant (hFc)
ALK-5,ALK-5ALK5,TGFβRI,tβR-I,LDS1A,TGFbetaRI,TGFB1R1,activin... |
Mouse | HEK293 Cells |
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Phosphorylated TGF-beta RI can then transiently bind and phosphorylate Smad2 and Smad3. TGF-beta functions as a tumor suppressor by inhibiting the cell cycle in the G1 phase. Administration of TGF-beta is able to protect against mammary tumor development in transgenic mouse models i... | |||
TMPY-06067 |
Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Protein (His)
NA Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa. | |||
TMPY-01134 |
Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is B0VX44. | |||
TMPY-05021 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA Protein
Harvey rat sarcoma viral oncogene homolog |
Influenza B | Baculovirus Insect Cells |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA Protein is expressed in Baculovirus insect cells. The predicted molecular weight is 61.7kDa and the accession number is C0LT35. | |||
TMPY-02343 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
Influenza B | HEK293 Cells |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.1 kDa and the accession number is C0LT38. | |||
TMPY-00957 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is A8W8K8. | |||
TMPY-05919 |
Influenza A H1N1 (A/Brisbane/02/2018) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Brisbane/02/2018) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa. | |||
TMPY-04848 |
Influenza B (B/Brisbane/60/2008) Neuraminidase/NA Protein
|
Influenza B | HEK293 Cells |
Influenza B (B/Brisbane/60/2008) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.1 kDa and the accession number is 4CPL_A. | |||
TMPY-04689 |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His)
E Protein, DENV |
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is AAC59274.1. | |||
TMPY-00954 |
Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is B0VX44. | |||
TMPY-02524 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
Influenza B | HEK293 Cells |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is C0LT35. | |||
TMPH-00014 |
Abrin-c Protein, Abrus precatorius, Recombinant (His & Myc)
|
Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis. Abrin-c Protein, Abrus precatorius, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight ... | |||
TMPH-03702 |
MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc)
|
Vibrio cholerae | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) is expressed in E. coli expression system wit... | |||
TMPY-06186 |
Influenza B (B/Brisbane/60/2008) Nucleoprotein/NP Protein (His)
Nucleoprotein,NP Protein |
Influenza B | Baculovirus Insect Cells |
Influenza B (B/Brisbane/60/2008) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 63.1 kDa. | |||
TMPH-02656 |
Fibrin Protein, Mouse, Recombinant (E. coli, His & Myc)
|
Mouse | E. coli |
N/A. Fibrin Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.6 kDa and the accession number is Q9CQS3. | |||
TMPY-04700 |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 578-680, His)
E Protein, DENV |
DENV | P. pastoris (Yeast) |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 578-680, His) is expressed in yeast with His tag. The predicted molecular weight is 13 kDa and the accession number is AAC59274.1. | |||
TMPH-00601 |
CS6 fimbrial subunit B Protein, E. coli, Recombinant (His & SUMO)
CS6 fimbrial subunit B,cssB |
E. coli | E. coli |
CS6 fimbrial subunit B Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-00527 |
Fibritin Protein, Enterobacteria phage T4, Recombinant (His & SUMO)
|
Enterobacteria phage T4 | E. coli |
Chaperone involved in tail fiber assembly and retraction. Acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. During phage assembly, twelve fibritin molecules attach to the phage neck via gp13: six molecules forming the collar and six molecules forming the whiskers. | |||
TMPH-03703 |
Zot Protein, Vibrio cholerae serotype O1, Recombinant (His)
|
Vibrio cholerae | E. coli |
Increases the permeability of the small intestine mucosa by affecting the structure of intercellular tight junctions (zonula occludens). Zot Protein, Vibrio cholerae serotype O1, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 48.4 kDa and the accession number is P38442. | |||
TMPY-04593 |
Influenza B (B/Brisbane/3/2007) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
Influenza B | HEK293 Cells |
Influenza B (B/Brisbane/3/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.9 kDa. | |||
TMPH-03722 |
Coagulase/fibrinolysin Protein, Yersinia pestis, Recombinant (His & Myc)
Plasminogen activator,Pla,Coagulase/fibrinolysin |
Yersinia pestis | E. coli |
Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (<30 degrees Celsius). Activates plasminogen by cleaving it. | |||
TMPY-01198 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is A8W8K8. | |||
TMPH-03704 |
Cytolysin Protein, Vibrio vulnificus, Recombinant (His & Myc)
Cytolysin,vvhA |
Vibrio vulnificus | E. coli |
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined. Cytolysin Protein, Vibrio vulnificus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 55.8 kDa and the accession number is P19247. | |||
TMPY-05311 |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 281-679, T76R,Q77E,W101R,L107R,His)
E Protein |
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 281-679, T76R,Q77E,W101R,L107R,His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is AAC59274.1. | |||
TMPH-00012 |
Abrin-a Protein, Abrus precatorius, Recombinant (E. coli, His)
|
Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis. Abrin-a Protein, Abrus precatorius, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 33.6... | |||
TMPH-02657 |
Fibrin Protein, Mouse, Recombinant (His & Myc)
|
Mouse | Baculovirus Insect Cells |
N/A. Fibrin Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 26.5 kDa and the accession number is Q9CQS3. | |||
TMPY-06166 |
Influenza A H1N1 (A/Brisbane/02/2018) Nucleoprotein/NP Protein (His)
NP Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Brisbane/02/2018) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.6 kDa. | |||
TMPY-05862 |
Influenza A H1N1 (A/swine/Cambridge/1939) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Cambridge/1939) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa. | |||
TMPH-03157 |
Fimbrillin Protein, Porphyromonas gingivalis, Recombinant (His & Myc)
|
Porphyromonas gingivalis | E. coli |
Fimbrillin Protein, Porphyromonas gingivalis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.9 kDa and the accession number is B2RH54. | |||
TMPJ-00744 |
Toxin B Protein, Vibriocholerae, Recombinant
Cholera enterotoxin γ chain,Choleragenoid,Cholera enterotoxi... |
Vibrio cholerae | E. coli |
Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself. | |||
TMPH-01334 |
Fibrinopeptide A Protein, Human, Recombinant (His)
|
Human | E. coli |
Fibrinopeptide A Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.1 kDa and the accession number is Q8WW76. | |||
TMPH-00620 |
F41 fimbrial Protein, E. coli, Recombinant (His & Myc)
|
E. coli | E. coli |
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. F41 fimbrial Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.4 kDa and the accession number is P11900. | |||
TMPH-00359 |
AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)
Alpha-ketoglutarate-dependent dioxygenase AlkB homolog,DNA o... |
Caulobacter vibrioides | E. coli |
AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is B8GWW6. | |||
TMPH-02467 |
Fimbrial protein Q Protein, Moraxella bovis, Recombinant (His)
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Moraxella bovis | E. coli |
Fimbrial protein Q Protein, Moraxella bovis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.9 kDa and the accession number is P07640. | |||
TMPH-00208 |
Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His)
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Bordetella pertussis | E. coli |
Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process. Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant ... | |||
TMPH-00829 |
Fibrinogen beta chain/FGB Protein, Horse, Recombinant
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Horse | E. coli |
Fibrinogen beta chain/FGB Protein, Horse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 53.2 kDa and the accession number is F6PH38. | |||
TMPH-00013 |
Abrin-a Protein, Abrus precatorius, Recombinant (Yeast, His)
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Abrus precatorius | P. pastoris (Yeast) |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis. Abrin-a Protein, Abrus precatorius, Recombinant (Yeast, His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 30.1 kDa and the accession ... | |||
TMPH-00015 |
Abrin-d Protein, Abrus precatorius, Recombinant (His & Myc)
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Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis. | |||
TMPH-00619 |
F17 fimbrial Protein, E. coli, Recombinant (His & SUMO)
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E. coli | E. coli |
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. F17 fimbrial Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.4 kDa and the accession number is P11312. | |||
TMPH-00031 |
Aerolysin Protein, Aeromonas sobria, Recombinant (His & Myc)
Hemolysin |
Aeromonas sobria | E. coli |
Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and cell death. The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter. | |||
TMPH-00642 |
K99 fimbrial Protein, E. coli, Recombinant (His & SUMO)
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E. coli | E. coli |
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.; FanC is the main component of the K99 fimbriae. K99 fimbrial Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.5 kDa and the accession number is P18103. | |||
TMPY-05067 |
Fibrinogen Gamma Chain Protein, Mouse, Recombinant
3010002H13Rik,fibrinogen γ chain,fibrinoge... |
Mouse | P. pastoris (Yeast) |
Loss of function mutations in FGG have been associated with fibrinogen deficiency. FGG mRNA was expressed abnormally in HCC and elevated plasma fibrinogen may serve as a useful predictor of clinical progression of HCC patients. Fibrinogen Gamma Chain Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 30.5 kDa and the accession number is Q3UEM7. | |||
TMPH-03705 |
NfuA Protein, Vibrio vulnificus, Recombinant
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Vibrio vulnificus | E. coli |
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, Vibrio vulnificus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.0 kDa and the accession number is Q8DDU2. | |||
TMPH-00643 |
K99 fimbrial Protein, E. coli, Recombinant
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E. coli | E. coli |
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.; FanC is the main component of the K99 fimbriae. | |||
TMPY-04732 |
Fibrinogen Gamma Chain Protein, Human, Recombinant
fibrinogen gamma chain,fibrinogen γ chain,... |
Human | P. pastoris (Yeast) |
Loss of function mutations in FGG have been associated with fibrinogen deficiency. FGG mRNA was expressed abnormally in HCC and elevated plasma fibrinogen may serve as a useful predictor of clinical progression of HCC patients. Fibrinogen Gamma Chain Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 32.2 kDa and the accession number is P02679-1. | |||
TMPH-01333 |
Fibrinogen beta chain Protein, Human, Recombinant (His)
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Human | E. coli |
Fibrinogen beta chain Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.8 kDa and the accession number is P02675. |