1517
481
4
1
274
Cat. No. | Product Name | ||
---|---|---|---|
L3800 | NF-κB 通路分子库 | 729 compounds | |
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L8600 | 泛素化化合物库 | 210 compounds | |
210 种泛素化相关的小分子,用于高通量和高内涵筛选; | |||
L1710 | 抗COVID-19化合物库 | 1133 compounds | |
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0005 |
Cell Counting Kit-8 (CCK-8)
Cell Counting Kit-8 (CCK-8) |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21708L |
Angiotensin 1/2 + A (2 - 8) Acetate
Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base) |
Others | Others |
Angiotensin 1/2 + A (2 - 8) Acetate 是一种血管收缩剂。 | |||
TP1385 |
Neurokinin A(4-10) TFA(97559-35-8 free base)
Neurokinin A(4-10) TFA |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Neurokinin A(4-10) TFA(97559-35-8 free base) 是一种速激肽 NK2 受体激动剂。 | |||
T9553 |
8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid
|
Others | Others |
8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car 是一种 H+/K+ ATPase 抑制剂,IC50=0.38μM。 | |||
TP1745L |
Ceratotoxin A acetate
Ceratotoxin A acetate(150671-04-8 Free base) |
Antibacterial | Microbiology/Virology |
Ceratotoxin A acetate 是从副腺分泌液中分离出来的,具有抗菌作用。 | |||
T20403 |
Dynorphin A (1-8)
PH-8P,Dynorphin (1-8) |
||
Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin. | |||
T6747 |
8-Bromo-cAMP sodium salt
8-Br-Camp sodium salt,8-溴腺苷-3',5'-环单磷酸钠,8-Bromo-cAMP(sodium salt),8-Bromo-cAMP |
PKA | Tyrosine Kinase/Adaptors |
8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) 是一种环 AMP 依赖性蛋白激酶 (PKA) 激活剂,是一种环 AMP 类似物。 | |||
TP1644 |
Influenza A NP(366-374) Strain A/PR/8/35
|
||
This peptide is an H2-Db-restricted epitope from the Influenza A/PR/8/34 nucleoprotein. | |||
T7774 |
A2793
2-[(5-氯-8-喹啉基)氧基]乙酸乙酯 |
Potassium Channel | Membrane transporter/Ion channel |
A2793 是 TWIK 相关酸敏感 K+通道 1(TASK-1)/TRESK 的双重抑制剂,对 mTRESK 的 IC50为 6.8 μM。它对 TRESK 选择性更好, 对 TREK-1 和 TALK-1 相对弱一些。 | |||
T8793 |
CBS1117
|
Influenza Virus | Microbiology/Virology |
CBS1117 是一种病毒进入抑制剂,对甲型流感病毒 A/Puerto Rico/8/34 的 IC50为 70 nM。它干扰血凝素介导的融合过程。 | |||
T35450 |
α-GalCer analog 8
α-GalCer analog 8,α-Galactosylceramide analog 8 |
||
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicati... | |||
TP1514 |
α-Neoendorphin (1-8)
α-Neoendorphin 1-8 |
||
α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin. α-Neoendorphin is an endogenous opioid peptide and is a part for the neoendorphins which are a group of endogenous opioid peptides derived from the proteolytic c | |||
T83798 |
8-bromo NAD+ sodium
8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+ |
||
8-bromo NAD+ 作为循环ADP-核糖(cADPR)抑制剂8-bromo cADPR的前药形式,通过CD38转化为8-bromo-cADPR。在1 mM浓度下,8-bromo NAD+ 阻止由N-formyl-Met-Leu-Phe (fMLP) 在分离的小鼠骨髓衍生的中性粒细胞内引起的细胞内钙水平增加和趋化作用。同时,在100 µM浓度下使用,减少了小鼠原代小胶质细胞中LPS诱导的亚硝酸盐产生以及TNF-α和IL-2的分泌。 | |||
T31173 |
Daaccal
2-Cys-5-cys-7-mearg-8-leu-dynorphin A (1-9)-NH2 |
||
Daaccal 可用于生命科学领域的相关研究。其产品编号为 T31173,CAS号为 103614-06-8。 | |||
TP1134 |
HCGRP-(8-37)
Human α-CGRP (8-37) |
||
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist | |||
T37369 |
Amyloid-β (1-8, A2V) Peptide
Amyloid-β (1-8, A2V) Peptide |
||
Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V). An Aβ (1-40) (Aβ40) A2V peptide increases the production of Aβ and the rate and amount of amyloid fibril formation in vitro, effects that can be reduced by coincubation with wild-type Aβ40. Aβ40 and Aβ42 levels are increased in CHO ... | |||
TP1100 |
[bAla8]-Neurokinin A(4-10)
MEN 10210 |
||
[bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist. | |||
T125496 |
Junipediol A 8-glucoside
|
||
Junipediol A 8-glucoside 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125496,CAS号为 188894-18-0。 | |||
T36157 |
8-iso Prostaglandin A1
8-iso Prostaglandin A1 |
||
8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane and a member in a large family of prostanoids of non-cyclooxygenase origin. It occurs as a common minor impurity in most commercial preparations of PGE1. The biological activity of 8-iso PGA1 has not been studied in depth or reported in the literature. | |||
T1906 |
Molibresib
GSK 525762A,GSK525762,(4S)-6-(4-氯苯基)-N-乙基-8-甲氧基-1-甲基-4H-[1,2,4]三唑并[4,3-a][1,4]苯并二氮杂卓-4-乙酰胺,I-BET 762 |
Epigenetic Reader Domain | Chromatin/Epigenetic |
Molibresib (GSK525762) 是一种 BET 溴结构域抑制剂,IC50为32.5在42.5 nM 之间。 | |||
T74762 |
Influenza A virus-IN-8
|
||
Influenza A virus-IN-8 (S5) 为一种大环肽,无细胞毒性,并作为甲型流感病毒 (IAV) 的有效抑制剂,显示出较好的蛋白酶稳定性。其对 H1 和 H5 变体的IC50值分别低至 6.7 nM 和 6.6 nM。此外,Influenza A virus-IN-8 能够与 HA 茎的一个保守区域结合,特别是对 H1 变体展现出 1.0 nM 的高亲和性Kd 值。 | |||
T83220 |
a-Bag Cell Peptide (1-8)
|
||
α-Bag Cell Peptide (1-8)为α-bag cell peptide的NH2末端片段,能够抑制左上象限(LUQ)神经元活动,并防止袋细胞去极化。 | |||
T76631 |
(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
|
||
(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) (E-2078) 是一种稳定的 Dynorphin A (1-8) 类似物,是 kappa 阿片受体 (KOR) 激动剂。 | |||
T66942 |
Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
|
||
Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66942,CAS号为 131666-45-0。 | |||
T65994 |
(6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
|
||
Wnt signaling is required for direct multiple biological processes and also plays key roles in the pathogenesis of various diseases. Cyclic AMP response element-binding protein (CREB) is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation... | |||
T6458 |
CYC-116
噻氯匹定 |
VEGFR; FLT; CDK; S6 Kinase; Aurora Kinase | Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
CYC116是一种有效的极光激酶 A 和 B 的抑制剂,Ki 值分别为8和9 nM。 | |||
T39669 |
TLR7/8/9-IN-1
TLR7/8/9-IN-1 |
TLR | Immunology/Inflammation |
TLR7/8/9-IN-1 是具有口服活性的Toll 样受体7/8/9小分子拮抗剂,IC50为43 nM。 | |||
T5561 |
TLR7/8 agonist 1 dihydrochloride
TLR7/8 agonist-5d,二盐酸TLR7/8 agonist 1 |
TLR | Immunology/Inflammation |
TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) 是 toll 样受体TLR7/TLR8的双重激动剂。 | |||
T22534 |
8-Hydroxy-DPAT hydrobromide
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-OH-DPAT hydrobromide |
5-HT Receptor | GPCR/G Protein; Neuroscience |
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一种选择性5-HT1A 激动剂,pIC50为 8.19。它对 5-HT1结合位点的亚型有近 1000 倍的选择性。 | |||
T13167 |
TLR7/8 agonist 3
|
TLR | Immunology/Inflammation |
TLR7/8 agonist 3 是TLR7/8激动剂。 | |||
T7617 |
Neurotensin(8-13)
神经降压素(8-13),Neurotensin(8-13)(3TFA) |
Neurotensin Receptor | GPCR/G Protein |
Neurotensin(8-13) 是神经降压素的活性片段,可导致细胞表面 NT1 受体 (NTR1) 密度降低。 | |||
T9160 |
4-Chloroquinolin-8-ol
|
Others | Others |
4-Chloroquinolin-8-ol 是一个组成部分。 | |||
T10746 |
CDK9-IN-8
|
CDK | Cell Cycle/Checkpoint |
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM). | |||
T4018 |
WST-8
WST8 |
Others | Others |
WST-8 是水溶性的四唑染料,WTS-8测定法的灵敏度比常规MTS 检测高。 | |||
T2290 |
8-Hydroxyquinoline-2-carboxaldehyde
|
Others | Others |
8-Hydroxyquinoline-2-carboxaldehyde 用作医药中间体。 | |||
T9938 |
RA371
EX-A4742 |
Others | Others |
RA371 (EX-A4742) 是 PTP1B-IN-8 的衍生物,PTP1B-IN-8 是 PTP1B 的抑制剂。 | |||
T7617L |
Neurotensin(8-13) 3TFA(60482-95-3(free base))
|
Neurotensin Receptor | GPCR/G Protein |
Neurotensin(8-13) 3TFA(60482-95-3(free base)) 是神经降压素 (NT) 片段,神经降压素 (8-13) 导致细胞表面 NT1 受体 (NTR1) 密度降低。 | |||
T36333 |
Z-IETD-AFC
|
||
Z-IETD-AFC 是 caspase-8 和颗粒酶 B 的荧光底物,可用于定量半胱天冬酶-8 或颗粒酶 B 的活性。 | |||
T0404 |
8-Hydroxyquinoline
Hydroxyquinoline,8-Quinolinol,羟基喹啉,Oxine,8-羟基喹啉,8-Oxychinolin |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
8-Hydroxyquinoline (8-Quinolinol) 是单质子二齿螯合剂, 也是转录抑制剂,防腐剂,消毒剂和杀虫剂。 | |||
T10199 |
GNF-PF-3777
8-Nitrotryptanthrin |
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
GNF-PF-3777 (8-Nitrotryptanthrin) 是人吲哚胺2,3-双加氧酶 2 (hIDO2) 抑制剂,能够降低IDO2活性,Ki=为 0.97 μM。 | |||
TP1914L1 |
BAM (8-22) acetate
BAM (8-22) acetate(412961-36-5 free base) |
Others | Others |
BAM (8-22) acetate 是脑啡肽原 A 的蛋白水解产物。BAM (8-22) acetate 可激活 Mas 相关的 G 蛋白偶联受体 (Mrgprs)、MrgprC11 和 hMrgprX1,并以 Mrgpr 依赖性方式诱导小鼠抓挠。 | |||
T14064 |
8-Bromo-cGMP sodium
|
Calcium Channel; PKA | Membrane transporter/Ion channel; Metabolism; Tyrosine Kinase/Adaptors |
8-Bromo-cGMP sodium 是一种 PKG 激活剂, 是 cGMP 的膜渗透性类似物。8-Bromo-cGMP sodium 具有缓解疼痛和血管舒张作用,可显着抑制 Ca2+ 宏观电流,抑制高 K+ 刺激的胰岛素释放。 | |||
T18629 |
PEG3-O-CH2COOH
PROTAC Linker 8,三聚乙二醇-乙酸 |
Others; PROTAC Linker | Others; PROTAC |
PEG3-O-CH2COOH (PROTAC Linker 8) 是一种属于 PEG 类的 PROTAC linker,可用于 SNIPER 分子的合成。 | |||
TQ0078 |
CDK-IN-2
CDK inhibitor II |
CDK | Cell Cycle/Checkpoint |
CDK-IN-2 (CDK inhibitor II) 是一种有效且特异性的 CDK9 抑制剂,IC50小于8 nM。 | |||
T40612 |
Manganese(salen) chloride
EUK-8 |
Others | Others |
Manganese(salen) chloride (EUK-8) 是超氧化物歧化酶和过氧化氢酶的一种模拟物,具有氧自由基清除性能。它可减轻内毒素血症猪的急性肺损伤。 | |||
T5187 |
MK-3903
MK 3903 |
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
MK-3903 是一种有选择性 AMP 激活的蛋白激酶 (AMPK) 激活剂,其EC50值为 8 nM。 | |||
T22832 |
H-8 hydrochloride
|
PKA | Tyrosine Kinase/Adaptors |
H-8 hydrochloride 是一种具有可逆性和 ATP 竞争性的 PKA 抑制剂。可用研究代谢疾病。 | |||
T77349 |
CCR1/5/8 activator 1
|
Phospholipase | Metabolism |
CCR1/5/8 activator 1 是胞质磷脂酶 A 抑制剂,具有抗真菌活性。 | |||
T11162 |
EGFR-IN-8
|
EGFR; c-Met/HGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
EGFR-IN-8 是 EGFR 和 c-Met 的双重抑制剂。 EGFR-IN-8可用于靶向 EGFR TKI 耐药的 NSCLC 的研究。 | |||
T22013 |
8-Aminoadenine
7H-purine-6,8-diamine,9H-Purine-6,8-diamine |
AChR | Neuroscience |
8-Aminoadenine (7H-purine-6,8-diamine) 是一种Adenine Receptor 的配体,Ki 为0.0341 μM。 | |||
T2364 |
Tucatinib
ARRY-380,Irbinitinib,ONT-380 |
EGFR; HER | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Tucatinib (ONT-380) 是可口服的选择性HER2抑制剂,IC50为8 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3284 |
8-Hydroxyodoroside A
|
Others | Others |
An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine and bisdeoxynarciclasine is provided, this antitumor agent has an advantage of having an excellent therapeutic effect of tumor and less side effects. | |||
TN7070 |
Ergostenol
delta8(14)-Ergostenol,alpha-Ergostenol,菜油甾醇,Ergost-8(14)-en-3beta-ol |
Others | Others |
Ergostenol (Ergost-8(14)-en-3beta-ol) 是一种生物前体和维生素 D2 的维生素原。 | |||
TN6908 |
Polyporusterone A
(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one |
||
Polyporusterone A 是一种从 P. umbellatus 的子实体中提取出来的三萜羧酸。Polyporusterone A 抑制自由基诱导的红细胞裂解 (溶血) ,可用于研究头发再生和牛皮癣。 | |||
TN6775 |
Acetylcytisine
1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,3-acetyl-1,2,3,4,5,6-hexahydro-, (1R)-,11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene |
Others | Others |
Acetylcytisine (11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene) 是 Genista tinctoria L. 草药的天然产物。 | |||
TN2830 |
26-Nor-8-oxo-alpha-onocerin
|
Others | Others |
26-Nor-8-oxo-alpha-onocerin can promote the osteoblast proliferation rate, the effect is time-dependent,concentration-dependent and differentiation state-dependent. | |||
T83257 |
7(8)-Dehydroschisandrol A
|
||
7(8)-Dehydroschisandrol A (Compound 4a)为从Schizandra chinensis Baill分离的木脂素,对激性胃溃疡表现出较弱抑制效果。 | |||
TN1142 |
8-Oxocoptisine
8-Oxycoptisine,8-氧黄连碱 |
Others | Others |
8-Oxocoptisine (8-Oxycoptisine) 是天然原小檗碱生物碱,具有抗癌作用。 | |||
T19165 |
8-Hydroxyguanine
8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine |
Endogenous Metabolite | Metabolism |
8-Hydroxyguanine (8 Hydroxyguanine)是由活性氧物质产生的主要诱变前损伤。 它导致G-T和A-C置换。8-Hydroxyguanine 是一种 RNA 氧化和 DNA 氧化损伤的生物标记物。8-Hydroxyguanine 具有致突变性和致癌性,常用于癌症实验中。 | |||
T8102 |
8-Aminooctanoic acid
|
Others | Others |
8-Aminooctanoic acid 是 ω-氨基脂肪酸,是在第 8 位带有一个氨基的辛酸,具有代谢活性。 | |||
T8343 |
8-Hydroxy-2'-deoxyguanosine
8-OHdG,8-Hydroxydeoxyguanosine,8-Hydroxy-2-Deoxyguanosine,2'-Deoxy-8-oxoguanosine,8 OHdG,8-Oxo-dG,8-OH-脱氧鸟嘌呤,8 Oxo dG,8-Oxo-2'-deoxyguanosine |
Endogenous Metabolite | Metabolism |
8-Hydroxy-2'-deoxyguanosine (8-OHdG) 是致癌反应和氧化应激的关键生物标志物。 | |||
TN3273 |
8-Deacetylyunaconitine
|
Others | Others |
8-Deacetylyunaconitine 是一种源自乌头的二萜生物碱。 | |||
TQ0154 |
8-Hydroxyguanosine
|
Others; Endogenous Metabolite | Metabolism; Others |
8-Hydroxyguanosine 是氧化应激的系统标记,也是氢氧自由基对 RNA 损伤的标记。 | |||
T6S1684 |
8-Gingerol
|
Antioxidant; Antibacterial; TRP/TRPV Channel | Membrane transporter/Ion channel; Microbiology/Virology; oxidation-reduction |
8-Gingerol 分离自姜的根状茎,是口服有效的 TRPV1激活剂,EC50值为5.0 µM。8-Gingerol 抑制 COX-2,还能抑制体外 H. pylori 的生长。 | |||
T6S2025 |
8-O-Acetylharpagide
8-O-乙酰哈巴苷,8-Acetylharpagide,3-Acetylharpagide,Acetylharpagide,8-O-Acetylharpagide |
Antibacterial | Microbiology/Virology |
8-O-Acetylharpagide 是从 Ajuga reptans 中分离得到的一种环烯醚萜,有抗肿瘤、抗病毒、抗菌和抗炎作用。它对豚鼠的离体平滑肌有生物活性。 | |||
TJS0312 |
7-hydroxy-4-methyl-8-nitrocoumarin
|
Others | Others |
7-Hydroxy-4-methyl-8-nitrocoumarin 是香豆素衍生物的一种。 | |||
T13701 |
Genistein 8-c-glucoside
G8CG |
Mitochondrial Metabolism | Metabolism |
Genistein 8-c-glucoside (G8CG) 诱导线粒体膜去极化从而导致细胞凋亡。Genistein 8-c-glucoside 是一种来源于 Lupinus luteus L.花中的天然葡萄糖苷。 | |||
TJP2865 |
7-methoxy-8-hydroxy-4-methylcoumarin
|
Others | Others |
7-methoxy-8-hydroxy-4-methylcoumarin 是分离自酸橙 (Citrus aurantium) 的一种化合物。 | |||
TN1017 |
Physion 8-O-β-D-glucoside
大黄素甲醚-8-o-β-D-葡萄糖苷,Physcion 1-O-beta-D-glucoside |
Others | Others |
Physion 8-O-β-D-glucoside 是一种 Fallopia multiflora 的活性成分,可用于头晕的研究。 | |||
T7993 |
8-Acetyl-7-Hydroxycoumarin
|
Antifungal | Microbiology/Virology |
8-Acetyl-7-Hydroxycoumarin 是一种天然化合物,具有抗真菌和抗菌活性。 | |||
TN7156 |
ochracin
8-hydroxy-3-methylisochroman-1-one,8-hydroxy-3-methyl-3,4-dihydroisochromen-1-one,3,4-Dihydro-8-hydroxy-3-methylisocoumarin,Ochracin |
Others | Others |
Ochracin (8-hydroxy-3-methyl-3,4-dihydroisochromen-1-one) 是一种海洋来源的天然产物,存在于Helicascus kanaloanus。 | |||
T5750 |
Oxyberberine
氧化小檗碱,Ketoberberine,Berlambine,8-Oxoberberine |
Others | Others |
Oxyberberine (8-Oxoberberine) 是天然的生物碱类物质。 | |||
T4715 |
2'-Deoxyguanosine monohydrate
2'-脱氧鸟苷一水合物,Guanine-2'-deoxyriboside |
Others; Endogenous Metabolite | Metabolism; Others |
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) 是内源性代谢产物的一种。 | |||
T3S1541 |
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan
rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-m,(7S,7'R)-双(3,4-亚甲二氧苯基)-rel-(8R,8'R)-二甲基四氢呋喃 |
Others | Others |
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan 为肉豆蔻果实中发现的化学成分。 | |||
T9503 |
PHYTOSPHINGOSINE
|
Apoptosis | Apoptosis |
Phytosphingosine 是具有抗癌作用的一种磷脂。在癌细胞中,它通过 caspase 8 的激活和 Bax 转位诱导细胞凋亡。 | |||
T2218 |
8-Azaguanine
Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337 |
Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others |
8-Azaguanine (SK 1150) 是一种具有潜在抗肿瘤活性的嘌呤类似物。它易于掺入核糖核酸中,干扰正常的生物合成途径,从而抑制细胞生长,可作为抗代谢药。 | |||
TN4674 |
Nortrachelogenin-8'-O-beta-glucoside
|
Others | Others |
Nortrachelogenin-8'-O-beta-glucoside 是一种具有二芳基羟基丁内酯骨架的木脂素,其分离自 Trachelospermum jasminoides (Lindl.) Lem 的叶和茎。 | |||
T7924 |
8-Bromoguanosine
|
Others | Others |
8-Bromoguanosine 是鸟苷的溴化衍生物。它是通过细胞内机制激活淋巴细胞发挥免疫刺激作用。 | |||
T9218 |
Andrograpanin
19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元 |
p38 MAPK | MAPK |
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) 是来自穿心莲的一种天然产物,具有抗炎和抗感染活性。 | |||
TN3120 |
5-Hydroxy-7-acetoxy-8-methoxyflavone
|
Histone Demethylase; Antiviral | Chromatin/Epigenetic; Immunology/Inflammation |
5-Hydroxy-7-acetoxy-8-methoxyflavone 是一种类黄酮化合物,可以抑制脂质过氧化,可能具有抗流感病毒活性。 | |||
TN2353 |
8-Hydroxyapigenin
Isoscutellarein |
Antioxidant; Influenza Virus | Microbiology/Virology; oxidation-reduction |
8-Hydroxyapigenin (Isoscutellarein) 是从植物黄芩中提取的黄铜类化合物,具有抗炎抗氧和抗流感病毒的活性。 | |||
T5430 |
[8]-Shogaol
8-SHOGAOL,8-姜烯酚 |
Apoptosis; COX | Apoptosis; Immunology/Inflammation; Neuroscience |
[8]-Shogaol 是生姜中的一种刺激性酚类天然产物,可诱导人白血病细胞凋亡,抑制 COX-2的IC50为17.5 μM,具有抗血小板活性,IC50为5 μM。 | |||
T12564 |
Prudomestin
3,5,7-Trihydroxy-4',8-dimethoxyflavone,3,5,7-三羟基-8,4'-二甲氧基黄酮 |
Xanthine Oxidase | Metabolism |
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) 是一种分离自 Prunus domestica 心材中,具有很强的黄嘌呤氧化酶(XO)抑制活性(IC50≈6 µM)。 | |||
T0908 |
Chlorquinaldol
5,7-Dichloro-8-hydroxy-2-methylquinoline,Chloquinan,氯喹那多 |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) 是一种抗菌剂, 有潜力研究局部皮肤病症和阴道感染。 | |||
T2845 |
Imperatorin
Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen |
TRP/TRPV Channel; AChR; AChE; NOD | Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB |
Imperatorin (8-Isopentenyloxypsoralene) 是NO synthesis 和BChE 的抑制剂,IC50分别为 9.2 μmol 和 31.4 μmol。它也是TRPV1的微弱激动剂,EC50为 12.6±3.2 μM。 | |||
T5582 |
β-Apo-8'-carotenal
ψ-胡萝卜醛,trans-β-apo-8'-carotenal,BETA-阿朴-8'-胡萝卜醛,Apocarotenal |
Others; P450 | Metabolism; Others |
β-Apo-8'-carotenal (Apocarotenal) 是一种存在于许多蔬菜、水果中的维生素原 A 类胡萝卜素,是大鼠CYP1A1和CYP1A2的诱导剂。 | |||
T3671 |
Vitexin-2"-O-rhamnoside
牡荆素鼠李糖苷,牡荆素-2-O-鼠李糖苷,2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside |
Others | Others |
Vitexin-2"-O-rhamnoside (Apigenin-8-C-glucoside) 是一种黄酮苷类化合物,存在于Cratagus pinnatifidaBge 中,对 H2O2介导的氧化应激损伤具有保护作用,可用于研究心血管系统疾病。 | |||
TN2023 |
8-Oxoepiberberine
氧化表小檗碱,Oxyepiberberine |
Others | Others |
8-Oxoepiberberine (Oxyepiberberine) 是口服左金方剂后血清中产生的生物碱代谢物。其中左金方剂是一种中药,可以用于胃肠道疾病的研究。 | |||
TN1146 |
8-Prenylnaringenin
8-Prenylnaringenin,8-异戊烯基柚皮素 |
Apoptosis; ROS | Apoptosis; Immunology/Inflammation |
8-prenylnaringenin 是一种从啤酒花穗中分离到的异戊烯类黄酮,具有细胞毒性。它能通过激活小鼠 Akt 磷酸化途径,使其从静止诱导的停用性肌肉萎缩中恢复。它能通过诱导内源性和外源性通路介导的凋亡,对 HCT-116 结肠癌细胞产生抗增殖活性。 | |||
TN1346 |
Oxypalmatine
8-Oxypalmatine |
Apoptosis | Apoptosis |
Oxypalmatine (8-Oxypalmatine) 是在 Phellodendron amurense 中分离出来的小檗碱型生物碱,通过抑制 PI3K/AKT 信号传导及其对乳腺癌类器官的功效来调节乳腺癌细胞的增殖和凋亡。 | |||
T3010 |
Xanthurenic Acid
8-Hydroxykynurenic acid,黄尿酸,4,8-Dihydroxyquinaldic acid,xanthurenate |
Apoptosis; Endogenous Metabolite; GluR | Apoptosis; Metabolism; Neuroscience |
Xanthurenic Acid (8-Hydroxykynurenic acid) 是通过 3-羟基犬尿氨酸转氨而由色氨酸代谢产生的分子,可激活 mGlu2/3 代谢型谷氨酸受体。在下丘脑的感觉传输过程中,它被认为是Group II 代谢型谷氨酸受体的激动剂。 | |||
TN2376 |
Fructo-oligosaccharide DP8/GF7
蔗果八糖,Fructo-oligosaccharide DP8 / GF7 |
Others | Others |
Fructo-oligosaccharide DP8/GF7 (Fructo-oligosaccharide DP8 / GF7) 是一种聚果糖,聚合度(DP=8)。Fructo-oligosaccharides 由 7 个果糖单元通过 (2→1)-β-糖苷键连接,并在非还原性末端具有 1 个 D-葡萄糖单元。 | |||
T7971 |
8-Amino-1-Naphthalenesulfonic Acid
|
Others | Others |
8-Amino-1-Naphthalenesulfonic Acid 是萘的衍生物,用作荧光染料和有机合成中的试剂。它是一种具有高Stokes 位移的高荧光化合物,使其成为广泛生物系统的理想荧光标记。 | |||
TN1341 |
8-Deoxygartanin
8-脱氧藤黄苷 |
Beta Amyloid; NF-κB; Parasite | Microbiology/Virology; Neuroscience; NF-κB |
8-Deoxygartanin 是山竹果中的异戊烯化呫吨酮。它是丁基胆碱酯酶选择性抑制剂,对阿尔茨海默病 (AD) 具有多功能活性,可能是有希望治疗 AD 的化合物。 | |||
TN1325 |
(2S)-6-Prenylnaringenin
(2S)-6-异戊烯基柚皮素,6-异戊二烯基柚皮素,6-Prenylnaringenin,6-PN |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
(2S)-6-Prenylnaringenin (6-Prenylnaringenin) 是强效植物雌激素 8-prenylnaringenin 的异构体,是前脑中最有效的化合物,在 α+β 结合位点上起GABAA 正变构调节剂的作用。 | |||
T5429 |
Theaflavin 3,3'-digallate
茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG |
Virus Protease; Antioxidant; HIV Protease; HSV | Microbiology/Virology; oxidation-reduction; Proteases/Proteasome |
Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂,IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制,可抑制 gp41 和 NS2B-3 蛋白酶的活性,并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚,有抗肿瘤作用。 | |||
T3924 |
Astragaloside II
黄芪皂苷 II,Astrasieversianin VIII |
TGF-beta/Smad | Stem Cells |
Astragaloside II (Astrasieversianin VIII) 是一种分离自黄芪中的天然化合物。 | |||
T5680 |
Aloin(mixture of A&B)
芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷 |
MMP; IL Receptor; Antibacterial; Antifungal | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
Aloin (mixture of A&B) 是一种从芦荟中分离出来的蒽醌衍生物。它是刺激性粒细胞基质金属蛋白酶的有效抑制剂。它具有多种生物活性,如抗炎、抗菌、抗真菌、抗氧化、抗肿瘤、抗糖尿病和免疫活性。 | |||
T5S2254 |
Swertianolin
Bellidifolin-8-O-Glucoside,当药醇苷 |
Others; HBV; Antibacterial; AChE | Microbiology/Virology; Neuroscience; Others |
Swertianolin (Bellidifolin-8-O-Glucoside) 是从Gentianella Acuta 分离得到的一种黄酮,具有抗 HBV 和抗菌活性,可抑制乙酰胆碱酯酶。 | |||
TN1861 |
Licoflavone C
4',5,7-Trihydroxy-8-prenylflavone |
Antioxidant; Antifungal | Microbiology/Virology; oxidation-reduction |
Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) 是从 Glycyrrhiza inflata 的根部分离出来的异戊二烯基黄酮化合物,具有抗氧化和抗真菌活性,在培养的人类外周淋巴细胞中,它对 DAU 或 MMC 诱导的染色体损伤具有保护作用。Licoflavone C 可用于研究真菌感染。 | |||
T3861 |
Isobavachalcone
Corylifolinin,Isobacachalcone,补骨脂乙素 |
Apoptosis; Others; Reactive Oxygen Species; Akt; Autophagy | Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Others; PI3K/Akt/mTOR signaling |
Isobavachalcone (Corylifolinin) 是来源于补骨脂的一种Akt 信号通路抑制剂,可诱导人类癌细胞凋亡,以IC50值为 7.92 μM 抑制 OVCAR-8 癌细胞生长,具有抗癌和抗增殖活性。它还能诱导 OVCAR-8 细胞中活性氧的产生。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00638 |
Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)
IFN-αB,IFN-alphaB,interferon, α8,... |
Human | HEK293 Cells |
Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is A0A7R8C381. | |||
TMPY-04337 |
Influenza A H1N1 (A/Puerto Rico/8/1934) Neuraminidase/NA Protein
NA Protein |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Puerto Rico/8/1934) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.1 kDa and the accession number is P03468.2. | |||
TMPY-01491 |
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin Protein (His)
Harvey rat sarcoma vir |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is P03452. | |||
TMPY-04537 |
PRL8A4 Protein, Rat, Recombinant (His)
Prlph,prolactin family 8, subf |
Rat | HEK293 Cells |
PRL8A4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5 kDa and the accession number is P33580. | |||
TMPY-01232 |
Angiotensinogen Protein, Human, Recombinant (His)
SERPINA8,angiotensinogen (serpin ... |
Human | HEK293 Cells |
Angiotensinogen Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.2 kDa and the accession number is B0ZBE2. | |||
TMPY-04501 |
Angiotensinogen Protein, Rat, Recombinant (His)
angiotensinogen (serpin peptidase inhibito... |
Rat | HEK293 Cells |
Angiotensinogen Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A6KJ10. | |||
TMPY-03637 |
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His)
Interferon α-B,interferon, alpha 8 |
Cynomolgus | HEK293 Cells |
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43 kDa and the accession number is G7PS89. | |||
TMPY-03620 |
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc)
Interferon α-B,interferon, alpha 8 |
Cynomolgus | HEK293 Cells |
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46 kDa and the accession number is G7PS89. | |||
TMPY-02160 |
Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His)
Integrin α8 β 1,integrin, α8,integrin, |
Human | HEK293 Cells |
Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 196 kDa and the accession number is P53708&P05556-1. | |||
TMPY-01501 |
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His)
Harvey rat sarcoma vir |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03452. | |||
TMPY-03663 |
FUT8 Protein, Hamster, Recombinant (aa 68-575, His)
FUT8,fucosyltransferase 8 |
Hamster | Baculovirus Insect Cells |
FUT8 Protein, Hamster, Recombinant (aa 68-575, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 63.8 kDa and the accession number is G3HCE4. | |||
TMPY-03648 |
Interferon alpha B/IFNA8 Protein, Human, Recombinant
IFN-αB,IFN-alphaB,interferon, alp... |
Human | HEK293 Cells |
Interferon alpha B/IFNA8 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38 kDa and the accession number is A0A7R8C381. | |||
TMPY-02219 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
NS1 Protein |
H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As... | |||
TMPY-02232 |
Angiotensinogen Protein, Mouse, Recombinant (His)
AngI,Serpina8,angiotensi... |
Mouse | HEK293 Cells |
Angiotensinogen Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is P11859. | |||
TMPY-02546 |
FUT8 Protein, Human, Recombinant (aa 68-575, His)
MGC26465,fucosyltransferase 8 ( |
Human | Baculovirus Insect Cells |
FUT8 Protein, Human, Recombinant (aa 68-575, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60 kDa and the accession number is Q9BYC5-1. | |||
TMPY-01382 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (I116M, His)
NP Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (I116M, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P03466. | |||
TMPY-02286 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His)
cholinergic receptor, muscarinic 1 |
H1N1 | E. coli |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.3 kDa and the accession number is B4UPA8. | |||
TMPJ-00404 |
EphA4 Protein, Human, Recombinant
Ephrin type-A receptor 4,TYRO1,HEK8,EK... |
Human | HEK293 Cells |
EphA4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 60-80 KDa and the accession number is P54764. | |||
TMPJ-00396 |
SEMA4D Protein, Human, Recombinant (aa 22-734, His)
A8,BB18,Semaphorin-4D,GR... |
Human | HEK293 Cells |
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/P... | |||
TMPJ-00405 |
EphA4 Protein, Human, Recombinant (hFc)
Ephrin type-A receptor 4,SEK,hEK8,TYRO1,Ty... |
Human | HEK293 Cells |
EphA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P54764. | |||
TMPJ-00991 |
S100A8 Protein, Rat, Recombinant (His)
Leukocyte L1 complex light chain,Migration... |
Rat | E. coli |
Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhi... | |||
TMPY-00256 |
ST8SIA1 Protein, Human, Recombinant (His)
SIAT8,SIAT8-A,G... |
Human | HEK293 Cells |
ST8SIA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.6 kDa and the accession number is Q92185-1. | |||
TMPY-03268 |
GABARAPL1 Protein, Human, Recombinant (His)
GEC1,APG8-LIKE,APG8L, |
Human | E. coli |
ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient deple... | |||
TMPY-03461 |
GABARAPL2 Protein, Human, Recombinant (His)
GATE16,ATG8,ATG8 |
Human | E. coli |
GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. | |||
TMPY-03416 |
TNFAIP8 Protein, Human, Recombinant (His)
GG2-1,tumor necrosis factor, alpha |
Human | E. coli |
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-alpha inducible anti-apoptotic protein with multiple roles in tumor growth and survival. by the creation of cellular autophagy events, TNFAIP8 promotes cell survival and drug resistance in prostate cancer cells. TNFAIP8 regulates Hippo pathway through interacting with LATS1 to prom... | |||
TMPJ-00187 |
CD300A Protein, Human, Recombinant (hFc & His)
CMRF35-like molecule 8,NK inhibitory receptor,CMRF-... |
Human | HEK293 Cells |
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granu... | |||
TMPJ-00406 |
EphA8 Protein, Human, Recombinant (His)
EPH- and ELK-related tyrosine kina |
Human | HEK293 Cells |
EphA8, also known as Hek3 and Eek, is a 120 kDa glycosylated member of the Eph family of transmembrane receptor tyrosine kinases. The A and B classes of Eph proteins are distinguished by Ephrin ligand binding preference but have a common structural organization. Eph-Ephrin interactions are widely involved in the regulation of cell migration, tissue morphogenesis, and cancer progression. Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent c... | |||
TMPJ-01382 |
HSPB8 Protein, Human, Recombinant (His)
Small stress protein-like protein HSP22,CRYA |
Human | E. coli |
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have bee... | |||
TMPY-06676 |
Cor a 8 Protein, Corylus avellana, Recombinant
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Corylus avellana | P. pastoris (Yeast) |
Cor a 8 Protein, Corylus avellana, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 9 kDa. | |||
TMPY-00056 |
Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma vir |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.9 kDa and the accession number is C7RWT2. | |||
TMPY-00273 |
Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma vir |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is C7RWT2. | |||
TMPY-00295 |
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma vir |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03452. | |||
TMPY-04592 |
Influenza A H4N2 (A/duck/Hunan/8-19/2009) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma vir |
H4N2 | HEK293 Cells |
Influenza A H4N2 (A/duck/Hunan/8-19/2009) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is E2JK05. | |||
TMPY-04893 |
Influenza A H4N2 (A/duck/Hunan/8-19/2009) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma vir |
H4N2 | Baculovirus Insect Cells |
Influenza A H4N2 (A/duck/Hunan/8-19/2009) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.8 kDa and the accession number is E2JK05. | |||
TMPY-02285 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein
NS2 Protein |
H1N1 | E. coli |
Non-structural protein 2 (NS2) plays a crucial role in the hepatitis C virus (HCV) assembly. NS2 was predicted to be composed of three transmembrane (TM) segments. Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a hydrophobic, transmembrane protein that is required not only for NS2-NS3 cleavage but also for infectious virus production.NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and ant... | |||
TMPY-06654 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (His)
NP Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.66 kDa and the accession number is AAM75159.1. | |||
TMPH-02348 |
Influenza A H1N1 (strain A/Puerto Rico/8/1934) Matrix protein 2 (His & Myc)
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H1N1 | E. coli |
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins ... | |||
TMPH-02354 |
Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO)
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H1N1 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPY-06140 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (I116M, His), Biotinylated
NP Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (I116M, His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P03466. | |||
TMPY-04060 |
Influenza A H3N2 (A/reassortant/IVR-155(Victoria/210/2009 x Puerto Rico/8/1934)) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma vir |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/reassortant/IVR-155(Victoria/210/2009 x Puerto Rico/8/1934)) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is D7SFH7. | |||
TMPY-01709 |
HIF-1 alpha Protein, Human, Recombinant (His)
bHLHe78,HIF-1 α,hypoxia inducible fa |
Human | E. coli |
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (HIF1). HIF1 is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has... | |||
TMPH-03419 |
Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His)
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RV-A | E. coli |
Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P03530. | |||
TMPY-03859 |
DHRS9 Protein, Human, Recombinant (His)
3α-HSD,RDHTBE,3ALPHA-HSD,RDH-E2,RETSDR... |
Human | E. coli |
Dehydrogenase/reductase (SDR family) member 9 (DHRS9) is aberrantly expressed in colorectal cancer (CRC), the decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in CRC. The human regulatory macrophage (Mreg) has emerged as a promising cell type for use as a cell-based adjunct immunosuppressive therapy in solid organ transplant recipients. DHRS9 is a specific and stable marker of human Mregs. | |||
TMPY-02820 |
SDF-1 Protein, Human, Recombinant (isoform a)
SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB12,T... |
Human | E. coli |
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2. | |||
TMPJ-00994 |
LTBR Protein, Mouse, Recombinant (hFc)
Tnfcr,Lymphotoxin-beta receptor,Tumor necrosis f |
Mouse | HEK293 Cells |
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs... | |||
TMPY-05717 |
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
Integrin alpha V β8,Integrin α V ... |
Human | HEK293 Cells |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This m... | |||
TMPY-04123 |
CEACAM1 Protein, Human, Recombinant (His & hFc)
CEACAM‑1,carcinoembryonic a |
Human | HEK293 Cells |
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8. | |||
TMPJ-00864 |
VEGF165 Protein, Human, Recombinant
Vascular Endothelial Growth F... |
Human | HEK293 Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul... | |||
TMPY-01085 |
VLDLR Protein, Human, Recombinant (His)
VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein ... |
Human | HEK293 Cells |
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ... | |||
TMPY-02287 |
Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)
KARP1,XRCC5 & XRCC6,KUB2,KU80,KAR... |
Human | Baculovirus Insect Cells |
X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repair protein XRCC5, Lupus Ku autoantigen protein p86, TLAA and XRCC5, is a nucleus and chromosome which belongs to the ku8 family. XRCC5 is a single-stranded DNA-dependent ATP-dependent helicase. XRCC5 has a role in chromosome translocation. X-ray repair cross-complementing protein... | |||
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