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Search Results for " apa "

169

抑制剂 & 化合物

21

天然产物

1

TargetMol 试剂盒

21

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
C0074	Mag Beads COOH High capacity (2.8 μm) 羧基磁珠 (2.8 μm)

TargetMol 试剂盒

羧基磁珠 (2.8 μm)

Cat.No: C0074

Cat. No.	Product Name	Target	Signaling Pathways
T23745	APA-APA-MPO APA APA MPO,APAAPAMPO
	APA-APA-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.
T40191	17-GMB-APA-GA
	17-GMB-APA-GA, a potent HSP90 inhibitor, is an ADC cytotoxin commonly employed for studying latent T. gondii infection.
T23746	APA-H-MPO APAHMPO
	APA-H-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.
T10820L1	Ciraparantag acetate Ciraparantag acetate(1438492-26-2 Free base)	Others	Others
	Ciraparantag acetate 是一种抗凝逆转剂，是一种小分子，专门设计用于通过电荷-电荷相互作用与普通肝素和低分子量肝素非共价结合。它显示出与直接口服抗凝剂 (DOAC) 相似的结合特性。
T14301	Apararenone MT-3995	Glucocorticoid Receptor	Endocrinology/Hormones
	Apararenone (MT-3995) 是一种新型的、非甾体类盐皮质激素受体 (mineralocorticoid receptor) 拮抗剂，正在开发用于糖尿病性肾病和非酒精性脂肪性肝炎的研究。
T12064	Niraparib (R-enantiomer) MK 4827 (R-enantiomer),Niraparib R-enantiomer	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib R-enantiomer (MK 4827 R-enantiomer) 是一种 PARP1抑制剂，IC50为 2.4 nM。
T9497	Niraparib tosylate monohyrate	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib tosylate monohyrate 也称为 MK-4827，是一种聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂，具有潜在的抗肿瘤活性。 MK4827 抑制 PARP 活性，增强 DNA 链断裂的积累，促进基因组不稳定性和细胞凋亡。 PARP 蛋白家族通过碱基切除修复 (BER) 途径检测和修复单链 DNA 断裂。
T7587	Tenapanor RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722	Sodium Channel	Membrane transporter/Ion channel
	Tenapanor (RDX 5791) 是钠氢离子交换NHE3的有效抑制剂, 对人和大鼠NHE3的IC50分别是5和10 nM。
TQ0245	Sapacitabine CS682,CYC682	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sapacitabine (CS682) 是一种核苷类似物前体，具有抗癌活性，可用于研究白血病。
T11465	Lenacapavir GS-6207	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Lenacapavir (GS-6207) 是一种有效的靶向衣壳的 HIV 复制抑制剂。 Lenacapavir 在 MT-4 细胞中显示出抗 HIV 活性，EC50 为 100 pM。
T5819	Rapastinel Trifluoroacetate Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) 是一种 NMDA 受体调节剂，具有甘氨酸位点部分激动剂性质，有研究抑郁症的潜力。
T3015	Olaparib AZD2281,奥拉帕尼,KU0059436	Mitophagy; PARP; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Olaparib (KU0059436) 是 PARP1/PARP2 的小分子抑制剂 (IC50=5/1 nM)，对 PARP tankyrase-1 的抑制活性较弱 (IC50=1.5 μM)，具有选择性和口服活性。Olaparib 具有自噬和线粒体自噬激活活性。
T0078	Lapatinib GSK572016,GW572016,拉帕替尼	EGFR; Ferroptosis; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Lapatinib (GW572016) 是一种 ErbB2 和 EGFR 的抑制剂 (IC50=9.2/10.8 nM)，具有口服活性。Lapatinib 具有抗肿瘤活性，可以用于治疗 HER2 过表达的晚期或转移性乳腺癌。
T13154	Tiapamil hydrochloride Ro 11-1781 hydrochloride,ORE 5002 hydrochloride	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Tiapamil hydrochloride (Ro 11-1781 hydrochloride) 是一种钙通道阻滞剂，具有抗高血压活性，可用于研究心绞痛和心血管疾病。
T4463	Rucaparib AG-14447,PF-01367338,瑞卡帕布,AG014699	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Rucaparib (PF-01367338) 是一种口服有效的 PARP 蛋白抑制剂，对 PARP-1 的 Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂，有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T63971	Canocapavir ZM-H1505R	HBV	Microbiology/Virology
	Canocapavir (ZM-H1505R)是一种新型可口服的 HBV 衣壳蛋白调节剂，具有抗病毒活性，可诱导 HBV 核心蛋白连接子区域的构象变化，可用于治疗乙型肝炎病毒。
T26641L	Apadenoson TFA BAY 68-4986 TFA,Apadenoson TFA(250386-15-3 Free base),Discontinued TFA	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Apadenoson TFA 是一种有效的腺苷 A2A 受体（A2AR）激动剂,可用于提高SARS感染患者的存活率。
T6127	Rucaparib Phosphate AG-014699 phosphate,PF-01367338,芦卡帕利,AG-014699,瑞卡帕布磷酸盐,PF-01367338 phosphate	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Rucaparib Phosphate (PF-01367338 phosphate) 是一种口服有效的PARP 蛋白抑制剂，对 PARP-1 的Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂，有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T4460	Dapagliflozin ((2S)-1,2-propanediol, hydrate) BMS-512148 (2S)-1,2-propanediol, hydrate,达格列净 (2S)-1,2-丙二醇水合物,Dapagliflozin propanediol monohydrate	SGLT	GPCR/G Protein
	Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) 是 Dapagliflozin 1,2-propanediol, hydrate 的 S 型异构体，是竞争性葡萄糖协同转运蛋白2 抑制剂，可促进尿液中葡萄糖的排泄，可用于糖尿病的研究。它诱导 HIF1表达并减轻肾脏 IR 损伤。
T15273	Fedovapagon VA483,A106483	Vasopressin Receptor	GPCR/G Protein
	Fedovapagon (VA106483) 是一种具有选择性和高效性的加压素 V2 受体 (V2R) 激动剂，可抑制斑马鱼节间血管的生长。Fedovapagon 可用于研究膀胱过度活动症、夜尿症和膀胱疼痛综合征。
T3231	Niraparib 尼拉帕尼,MK-4827	Apoptosis; Others; PARP	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	Niraparib (MK-4827) 是一种 PARP 抑制剂，可以抑制 PARP1 和 PARP2 (IC50=3.8/2.1 nM)，具有选择性。Niraparib 具有抗肿瘤活性，可以抑制 DNA 损伤修复、诱导细胞凋亡。
T60097	Methyl (E)-sinapate	Others	Others
	methyl (E)-sinapate 从 Polygala sibirica L.var. megalopha Fr 中分离得到。
T2339	Apalutamide ARN-509	Androgen Receptor; GABA Receptor	Endocrinology/Hormones; Membrane transporter/Ion channel; Neuroscience
	Apalutamide (ARN-509) 是一种有效、竞争性的雄激素受体 (AR) 拮抗剂(IC50:16 nM)。
T2389	Dapagliflozin 达格列净,BMS-512148	SGLT; HIF	Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein
	Dapagliflozin (BMS-512148) 竞争性的葡萄糖协同转运蛋白2 (SGLT2) 抑制剂，可促进尿液中葡萄糖的排泄，在糖尿病 (DM) 研究中具有价值。Dapagliflozin 诱导 HIF1表达并减轻肾脏 IR 损伤。
T0113	Mebhydrolin napadisylate Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,美海屈林萘二磺酸盐,Omeril,Diazoline	5-HT Receptor; AChR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Mebhydrolin napadisylate (Incidal) 是一种抗组胺药，用于缓解组胺释放引起的过敏症状，如鼻过敏和过敏性皮肤病。
T9593	Senaparib IMP4297	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Senaparib (IMP4297) 是一种选择性和口服有效的PARP1/2抑制剂，具有强效的抗肿瘤活性。
T68055	Devapamil Devapamilo,Devapamilum	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Devapamil (Devapamilo) 是一种苯烷基胺，以使用依赖性方式阻断来自膜细胞内侧的 L 型钙电流。
T1010	Verapamil hydrochloride Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride	P450; Calcium Channel; P-gp	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Verapamil hydrochloride (Verapamil HCl) 是一种钙通道阻滞剂，是一种可口服的 P 糖蛋白 (P-gp) 抑制剂，可抑制CYP3A4，用于高血压、心律不齐和心绞痛的研究。
T6235	Lapatinib Ditosylate Lapatinib (GW-572016) Ditosylate,二甲苯磺酸拉帕替尼,二对甲苯磺酸拉帕替尼,GW-572016 ditosylate,Tykerb ditosylate	EGFR; Ferroptosis; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Lapatinib Ditosylate (Tykerb ditosylate) 是一种有效的 EGFR 和 ErbB2 抑制剂，对 EGFR 和 ErbB2的 IC50值分别为 10.8 和 9.2 nM。它用于治疗晚期乳腺癌和其他实体瘤。
T6892	Niraparib tosylate 尼拉帕利,MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate,尼拉帕尼对苯甲磺酸盐	Apoptosis; PARP	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib tosylate (MK-4827(tosylate)) 是一种高效的，具有生物口服利用度的PARP1和PARP2抑制剂，IC50分别为 3.8 和 2.1 nM。它抑制 DNA 损伤修复，诱导凋亡并具有抗肿瘤活性。
T16807	Rucaparib monocamsylate 瑞卡帕布樟脑磺酸盐,Rucaparib Camsylate	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Rucaparib monocamsylate (Rucaparib Camsylate) 是一种口服有效的 PARP 蛋白抑制剂，对 PARP-1 的Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂，有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T16339	Norverapamil hydrochloride (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米	Calcium Channel; P-gp; Drug Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Norverapamil hydrochloride (D591 hydrochloride) 是 Verapamil 的 N-去甲基代谢物，是 L 型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。
T7013	Vorapaxar SCH 530348,MK-5348,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar (MK-5348) 是抗血小板药物，是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它靠剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集。
TP1223L	Apamin acetate Apamine acetate,Apamin acetate(24345-16-2 Free base)	Potassium Channel	Membrane transporter/Ion channel
	Apamin acetate (Apamine acetate) 是一种具有选择性的 Ca2+ 激活的 K+ (SK) 通道的阻断剂，是在蜂毒素中发现的一种 18 个氨基酸的肽类神经毒素。Apamin acetate 可增强皮质神经元撕裂损伤后的神经突生长和再生。Apamin acetate 具有抗炎和抗纤维化的作用。
T11506	Guaiapate Mg 5454,Klamar	Others	Others
	Guaiapate 具有止咳镇静作用。
T3353	Niraparib hydrochloride 尼拉帕利盐酸盐,MK-4827 hydrochloride,MK-4827 (hydrochloride)	Apoptosis; Others; PARP	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	Niraparib hydrochloride (MK-4827 hydrochloride) 是一种具有口服活性的PARP1和PARP2抑制剂，IC50值分别为 3.8 nM 和 2.1 nM。它抑制 DNA 损伤修复，诱导凋亡并具有抗肿瘤活性。
TQ0125	Capadenoson BAY 68-4986,卡帕诺生	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Capadenoson (BAY 68-4986) 是 A1 腺苷受体的选择性激动剂。
T2480	Apabetalone RVX-208,RVX000222,阿帕他隆	Epigenetic Reader Domain; HIV Protease	Chromatin/Epigenetic; Microbiology/Virology; Proteases/Proteasome
	Apabetalone (RVX000222) 是一种 BET 溴结构域抑制剂，用于研究治疗糖尿病、动脉粥样硬化和冠状动脉疾病。
T6007	Birinapant TL32711,比瑞那帕	Apoptosis; IAP; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Birinapant (TL32711) 是一种二价 Smac 模拟物，是 XIAP 和 cIAP1的强效拮抗剂，Kd 值分别为 45 nM 和小于 1 nM。它靶向与 TRAF2 相关的 cIAP，并消除 TNF 诱导的 NF-κB 活化。
T6763	Xevinapant ARRY-334543,SM-406,AT406,Debio-1143	IAP	Apoptosis
	Xevinapant (Debio-1143) 是一种有效的 Smac 模拟物和 IAP 的拮抗剂，能够抑制 XIAP，cIAP1 和 cIAP2 蛋白，Ki 值分别为 66.4，1.9 和 5.1 nM。
T22323	Enoxaparin sodium	Thrombin	Proteases/Proteasome
	Enoxaparin sodium 是一种低分子量肝素 (LMWH)，已获得美国 FDA 批准，可用于医疗管理的 ST 段心肌梗死 (STEMI) 或 STEMI 及随后的经皮冠状动脉介入治疗 (PCI) 患者。它与抗凝血酶结合并增强其作用，并抑制凝血因子 XIa、IXa、Xa 和 IIa（凝血酶），从而防止血栓形成。
T3218	Napabucasin BBI608	STAT	JAK/STAT signaling; Stem Cells
	Napabucasin (BBI608) 是一种口服的 Stat3 和 Y 干细胞活性抑制剂。
T15052	Dapansutrile	NOD-like Receptor (NLR); NOD	Immunology/Inflammation; NF-κB
	Dapansutrile 是一种口服有活性的 NLRP3 炎性小体选择性抑制剂。它具有抗炎特性，可用于研究缓解疼痛。
T9430	Venadaparib NOV140101,IDX-1197	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Venadaparib (NOV140101) 是一种选择性和具有口服活性的 PARP 抑制剂，对 PARP1和 PARP2的 IC50分别为 1.4 和 1.0 nM。它可防止 DNA 单链断裂 (SSB) 的修复，可研究实体瘤。
T21521L	Papain Inhibitor acetate 乙氨酸-乙氨酸-酪氨酸-精氨酸,GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate （70195-20-9 free base)	Others	Others
	Papain Inhibitor acetate (Gly-Gly-Tyr-Arg) 是木瓜蛋白酶的亲和配体。
T16999	Tavapadon PF-6649751,CVL-751	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Tavapadon (CVL-751) 是一种具有口服活性，高选择性的多巴胺 D1/D5受体部分激动剂，它可有效促进运动并减少残疾，对帕金森氏病具有潜在的应用价值。
T74048	PAPA NONOate	Endogenous Metabolite; NO Synthase	Immunology/Inflammation; Metabolism
	PAPA NONOate 是一种依赖于 pH 调节的 NO 供体。PAPA NONOate 具有潜在的抗肿瘤活性，通过增加伤口部位的胶原合成率，可用于研究糖尿病伤口愈合障碍。
T4434	Tirapazamine Tirazone,Win59075,SR4233,替拉扎明,SR259075	Others	Others
	Tirapazamine (Win59075) 是抗癌剂，对实体瘤中的缺氧细胞具有选择性细胞毒性，促使 DNA 中的单链和双链断裂，碱基损伤和细胞死亡。
T4492	pocapavir SCH-48973,V-073	Virus Protease; Antiviral	Immunology/Inflammation; Microbiology/Virology
	Pocapavir (SCH-48973) 是一种具有口服活性的研究性肠道病毒衣壳抑制剂，可防止病毒粒子进入细胞后脱壳。
T3098	Vorapaxar sulfate SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar sulfate (Zontivity) 是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集，是抗血小板药物。

化合物

APA-APA-MPO

Cat.No: T23745

Synonym: APA APA MPO,APAAPAMPO

17-GMB-APA-GA

Cat.No: T40191

Cat.No: T23746

Synonym: APAHMPO

Ciraparantag acetate

Cat.No: T10820L1

Synonym: Ciraparantag acetate(1438492-26-2 Free base)

Target: Others

Cat.No: T14301

Synonym: MT-3995

Target: Glucocorticoid Receptor

Niraparib (R-enantiomer)

Cat.No: T12064

Synonym: MK 4827 (R-enantiomer),Niraparib R-enantiomer

Target: PARP

Niraparib tosylate monohyrate

Cat.No: T9497

Target: PARP

Cat.No: T7587

Synonym: RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722

Target: Sodium Channel

Cat.No: TQ0245

Synonym: CS682,CYC682

Target: Nucleoside Antimetabolite/Analog

Cat.No: T11465

Synonym: GS-6207

Target: Others, HIV Protease

Rapastinel Trifluoroacetate

Cat.No: T5819

Synonym: Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate

Target: NMDAR, iGluR

Cat.No: T3015

Synonym: AZD2281,奥拉帕尼,KU0059436

Target: Mitophagy, PARP, Autophagy

Cat.No: T0078

Synonym: GSK572016,GW572016,拉帕替尼

Target: EGFR, Ferroptosis, Autophagy

Tiapamil hydrochloride

Cat.No: T13154

Synonym: Ro 11-1781 hydrochloride,ORE 5002 hydrochloride

Target: Calcium Channel

Cat.No: T4463

Synonym: AG-14447,PF-01367338,瑞卡帕布,AG014699

Target: PARP

Cat.No: T63971

Synonym: ZM-H1505R

Target: HBV

Apadenoson TFA

Cat.No: T26641L

Synonym: BAY 68-4986 TFA,Apadenoson TFA(250386-15-3 Free base),Discontinued TFA

Target: Adenosine Receptor

Rucaparib Phosphate

Cat.No: T6127

Synonym: AG-014699 phosphate,PF-01367338,芦卡帕利,AG-014699,瑞卡帕布磷酸盐,PF-01367338 phosphate

Target: PARP

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Cat.No: T4460

Synonym: BMS-512148 (2S)-1,2-propanediol, hydrate,达格列净 (2S)-1,2-丙二醇水合物,Dapagliflozin propanediol monohydrate

Target: SGLT

Cat.No: T15273

Synonym: VA483,A106483

Target: Vasopressin Receptor

Cat.No: T3231

Synonym: 尼拉帕尼,MK-4827

Target: Apoptosis, Others, PARP

Methyl (E)-sinapate

Cat.No: T60097

Target: Others

Cat.No: T2339

Synonym: ARN-509

Target: Androgen Receptor, GABA Receptor

Cat.No: T2389

Synonym: 达格列净,BMS-512148

Target: SGLT, HIF

Mebhydrolin napadisylate

Cat.No: T0113

Synonym: Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,美海屈林萘二磺酸盐,Omeril,Diazoline

Target: 5-HT Receptor, AChR, Histamine Receptor

Cat.No: T9593

Synonym: IMP4297

Target: PARP

Cat.No: T68055

Synonym: Devapamilo,Devapamilum

Target: Calcium Channel

Verapamil hydrochloride

Cat.No: T1010

Synonym: Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride

Target: P450, Calcium Channel, P-gp

Lapatinib Ditosylate

Cat.No: T6235

Synonym: Lapatinib (GW-572016) Ditosylate,二甲苯磺酸拉帕替尼,二对甲苯磺酸拉帕替尼,GW-572016 ditosylate,Tykerb ditosylate

Target: EGFR, Ferroptosis, Autophagy

Niraparib tosylate

Cat.No: T6892

Synonym: 尼拉帕利,MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate,尼拉帕尼对苯甲磺酸盐

Target: Apoptosis, PARP

Rucaparib monocamsylate

Cat.No: T16807

Synonym: 瑞卡帕布樟脑磺酸盐,Rucaparib Camsylate

Target: PARP

Norverapamil hydrochloride

Cat.No: T16339

Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米

Target: Calcium Channel, P-gp, Drug Metabolite

Cat.No: T7013

Synonym: SCH 530348,MK-5348,沃拉帕沙

Target: Protease-activated Receptor

Apamin acetate

Cat.No: TP1223L

Synonym: Apamine acetate,Apamin acetate(24345-16-2 Free base)

Target: Potassium Channel

Cat.No: T11506

Synonym: Mg 5454,Klamar

Target: Others

Niraparib hydrochloride

Cat.No: T3353

Synonym: 尼拉帕利盐酸盐,MK-4827 hydrochloride,MK-4827 (hydrochloride)

Target: Apoptosis, Others, PARP

Cat.No: TQ0125

Synonym: BAY 68-4986,卡帕诺生

Target: Adenosine Receptor

Cat.No: T2480

Synonym: RVX-208,RVX000222,阿帕他隆

Target: Epigenetic Reader Domain, HIV Protease

Cat.No: T6007

Synonym: TL32711,比瑞那帕

Target: Apoptosis, IAP, HIV Protease

Cat.No: T6763

Synonym: ARRY-334543,SM-406,AT406,Debio-1143

Target: IAP

Enoxaparin sodium

Cat.No: T22323

Target: Thrombin

Cat.No: T3218

Synonym: BBI608

Target: STAT

Cat.No: T15052

Target: NOD-like Receptor (NLR), NOD

Cat.No: T9430

Synonym: NOV140101,IDX-1197

Target: PARP

Papain Inhibitor acetate

Cat.No: T21521L

Synonym: 乙氨酸-乙氨酸-酪氨酸-精氨酸,GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate （70195-20-9 free base)

Target: Others

Cat.No: T16999

Synonym: PF-6649751,CVL-751

Target: Dopamine Receptor

Cat.No: T74048

Target: Endogenous Metabolite, NO Synthase

Cat.No: T4434

Synonym: Tirazone,Win59075,SR4233,替拉扎明,SR259075

Target: Others

Cat.No: T4492

Synonym: SCH-48973,V-073

Target: Virus Protease, Antiviral

Vorapaxar sulfate

Cat.No: T3098

Synonym: SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙

Target: Protease-activated Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T9218	Andrograpanin 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元	p38 MAPK	MAPK
	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) 是来自穿心莲的一种天然产物，具有抗炎和抗感染活性。
T4136	Lapachol Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin	Others; Influenza Virus; Antibacterial; Parasite; Antifungal	Microbiology/Virology; Others
	Lapachol (CI75490) 是从Tabebuia avellanedae 中分离得到的一种萘醌。它具有具有抗菌、抗炎、镇痛、抗肿瘤和抗生素特性。
TN7058	Dihydrolapachenole 6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene	Others	Others
	Dihydrolapachenole (6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene) 可分离自T. chrysantha。
TN2281	Sinapaldehyde trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde,TRANS-3,5-二甲氧基-4-羟基肉桂醛,芥子醛	Antibacterial	Microbiology/Virology
	Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) 对耐甲氧西林的金黄色葡萄球菌和大肠杆菌有抗菌作用，MIC 值都为 128 μg/mL。
T6004	Tetrahydropapaverine hydrochloride Tetrahydropapaverine HCl,Norlaudanosine HCl,Tetrahydroalkali hydrochloride,四氢罂粟碱盐酸盐	Hydroxylase	Metabolism
	Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) 是一种四氢异喹啉类药物。它对多巴胺神经元有神经毒性作用。
TN4893	Rapanone 拉帕酮,2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone,2,5-Dihydroxy-3-tridecylcyclohexa-2,5-diene-1,4-dione,酸藤子醌	Apoptosis; Phospholipase; Antibacterial; Parasite	Apoptosis; Metabolism; Microbiology/Virology
	Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) 是一种具有广泛生物活性的天然苯醌，如抗肿瘤、抗氧化、抗炎、抗菌和抗寄生虫活性。它还是选择性人滑膜 PLA2抑制剂，IC50值为 2.6 μM。
TN1375	α-Lapachone ALPHA-拉杷醌,alpha-Lapachone	Topoisomerase; Antifection	DNA Damage/DNA Repair; Microbiology/Virology
	α-Lapachone 具有杀锥虫作用。
T19503	Papain	Others; Cysteine Protease	Others; Proteases/Proteasome
	Papain 是一种半胱氨酸蛋白酶，是肽酶 C1 家族中一员，在食品、医药、化妆品、纺织等具有广泛的应用。
T6407	β-Lapachone 3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮,Beta-Lapachone,NSC-26326,SL-11001,ARQ-501	IDO; Apoptosis; Topoisomerase; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism
	β-Lapachone (ARQ-501) 是一种萘醌类天然产物，是拓扑异构酶 I 抑制剂，通过抑制细胞周期进程来诱导细胞凋亡。
T1537	Rapamycin Sirolimus,AY 22989,雷帕霉素,NSC-2260804	Others; Endogenous Metabolite; Antibiotic; mTOR; Autophagy; Antifungal	Autophagy; Metabolism; Microbiology/Virology; Others; PI3K/Akt/mTOR signaling
	Rapamycin (AY 22989) 属于大环内酯类天然产物，是一种 mTOR 抑制剂，具有特异性（HEK293 细胞：IC50=0.1 nM）。Rapamycin 具有免疫抑制活性，并能诱导自噬。
TN1569	Deoxylapachol	Antifection; Antifungal	Microbiology/Virology
	Deoxylapachol 是新西兰褐藻Landsburgia quercifolia 的主要细胞毒性成分，有抗真菌和抗癌活性。
TN5027	Sinapaldehyde glucoside	Others	Others
	Sinapaldehyde glucoside是一种天然产物，属于芸香科黄柏属，其产品编号为 TN5027，CAS号为 154461-65-1。Sinapaldehyde glucoside可用作对照参考。
TN6365	3-Deoxy-11,13-dihydroisosecotanapartholide
	3-Deoxy-11,13-dihydroisosecotanapartholide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6365，CAS号为 572924-43-7。
TN3318	9-Hydroxy-alpha-lapachone	Antifection	Microbiology/Virology
	9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. It may have anti-inflammatory activity, it exhibits potent inhi
TN1929	Methyl sinapate 芥子酸甲酯	Others	Others
	Methyl sinapate can increase the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV.
TN3321	9-Methoxy-alpha-lapachone	Others	Others
	9-Methoxy-alpha-lapachone has antitumor-promoting effect, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein- Barr virus early antigen (EBV-EA) activation in Raji cells.
T25305	Demethoxyrapamycin AY 24668,AY24668,AY-24668
	Demethoxyrapamycin is a new antifungal antibiotic agent which is co-produced with rapamycin by Streptomyces hygroscopicus.
TN3019	4,9-Dihydroxy-alpha-lapachone	Others	Others
	4,9-Dihydroxy-alpha-lapachone has antitumor-promoting effects, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells. 4,9-Dihydroxy-alpha-l
T79984	Chaparrinone	Parasite	Microbiology/Virology
	Chaparrinone为苦木素类化合物，源自Eurycoma Harmandiana根部提取。该物质对Plasmodium falciparum和P-388细胞展示出抗疟及细胞毒效应，IC50值分别为0.037 μg/mL和0.34 μg/mL。
T65249	Hydroxylapatite
	Hydroxylapatite 是一种天然产物，可用于生命科学领域的相关研究，其产品编号为 T65249。
TN4269	Isocarapanaubine	Others	Others
	Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica.

天然产物

Cat.No: T9218

Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元

Target: p38 MAPK

Cat.No: T4136

Synonym: Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin

Target: Others, Influenza Virus, Antibacterial, Parasite, Antifungal

Dihydrolapachenole

Cat.No: TN7058

Synonym: 6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene

Target: Others

Cat.No: TN2281

Synonym: trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde,TRANS-3,5-二甲氧基-4-羟基肉桂醛,芥子醛

Target: Antibacterial

Tetrahydropapaverine hydrochloride

Cat.No: T6004

Synonym: Tetrahydropapaverine HCl,Norlaudanosine HCl,Tetrahydroalkali hydrochloride,四氢罂粟碱盐酸盐

Target: Hydroxylase

Cat.No: TN4893

Synonym: 拉帕酮,2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone,2,5-Dihydroxy-3-tridecylcyclohexa-2,5-diene-1,4-dione,酸藤子醌

Target: Apoptosis, Phospholipase, Antibacterial, Parasite

Cat.No: TN1375

Synonym: ALPHA-拉杷醌,alpha-Lapachone

Target: Topoisomerase, Antifection

Cat.No: T19503

Target: Others, Cysteine Protease

Cat.No: T6407

Synonym: 3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮,Beta-Lapachone,NSC-26326,SL-11001,ARQ-501

Target: IDO, Apoptosis, Topoisomerase, Autophagy

Cat.No: T1537

Synonym: Sirolimus,AY 22989,雷帕霉素,NSC-2260804

Target: Others, Endogenous Metabolite, Antibiotic, mTOR, Autophagy, Antifungal

Cat.No: TN1569

Target: Antifection, Antifungal

Sinapaldehyde glucoside

Cat.No: TN5027

Target: Others

3-Deoxy-11,13-dihydroisosecotanapartholide

Cat.No: TN6365

9-Hydroxy-alpha-lapachone

Cat.No: TN3318

Target: Antifection

Methyl sinapate

Cat.No: TN1929

Synonym: 芥子酸甲酯

Target: Others

9-Methoxy-alpha-lapachone

Cat.No: TN3321

Target: Others

Demethoxyrapamycin

Cat.No: T25305

Synonym: AY 24668,AY24668,AY-24668

4,9-Dihydroxy-alpha-lapachone

Cat.No: TN3019

Target: Others

Cat.No: T79984

Target: Parasite

Hydroxylapatite

Cat.No: T65249

Isocarapanaubine

Cat.No: TN4269

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00644	Aminopeptidase A Protein, Human, Recombinant (His) APA,glutamyl aminopeptidase,ENPEP,gp160,CD249	Human	Baculovirus Insect Cells
	Aminopeptidase A Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 107.2 kDa and the accession number is Q07075.
TMPY-02896	Aminopeptidase A Protein, Mouse, Recombinant (His) Ly-51,6030431M22Rik,ENPEP,APA,Bp-1/6C3,glutamyl ami...	Mouse	Baculovirus Insect Cells
	Aminopeptidase A Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P16406.
TMPH-02177	Tapasin Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). Tapasin Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.4 kDa and the accession number is O15533.
TMPH-00808	HBV-D subtype ayw (isolate Japan/JYW796/1988) Protein X (His)	HBV-D	E. coli
	HBV-D subtype ayw (isolate Japan/JYW796/1988) Protein X (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is Q9QMI3.
TMPH-00573	DAPA aminotransferase Protein, E. coli, Recombinant (His & Myc) DAPA AT,bioA,7,8-diaminononanoate synthase,DAPA...	E. coli	E. coli
	Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Complements a bioU deletion in Synechocystis PCC 6803.
TMPH-03650	Turnip mosaic virus (TuMV) (strain Japanese) Genome polyprotein (His & Myc)	TuMV	E. coli
	N/A. Turnip mosaic virus (TuMV) (strain Japanese) Genome polyprotein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 66.6 kDa and the accession number is Q9ICI2.
TMPY-01622	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is A0FFY3.
TMPH-00347	Papain Protein, Carica papaya, Recombinant (His)	Carica papaya	E. coli
	Papain Protein, Carica papaya, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is P00784.
TMPY-00567	Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H2N2	HEK293 Cells
	Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q6XU87.
TMPY-06031	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA1 Protein (His), Biotinylated Harvey rat sarcoma viral oncogene homolog	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA1 Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is A0FFY3.
TMPY-05682	SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His) is expressed in E. coli expression system. The predicted molecular weight is 36.79 kDa and the accession number is QVD65746.1.
TMPY-04894	SARS-CoV (strain WH20) Plpro/papain-like protease (His)	SARS	E. coli
	SARS-CoV (strain WH20) Plpro/papain-like protease (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 36.65 kDa and the accession number is AAX16193.1.
TMPY-06038	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA Protein (His), Biotinylated Harvey rat sarcoma viral oncogene homolog	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is A0FFY3.
TMPH-00714	SapA Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Not part of a putrescine export system. Very similar to a S.typhimurium protein implicated in antimicrobial peptide resistance, but the SapBCDF operon in E.coli is implicated in putrescine export. SapA Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 66.9 kDa and the accession number is Q47622.
TMPY-00254	Tapasin Protein, Human, Recombinant (His) TAP binding protein (tapasin),NGS17,TPN,TPSN,TA...	Human	HEK293 Cells
	Tapasin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is AAH80574.1.
TMPJ-01431	SARS-CoV-2 Papain-Like Protease Protein PLpro,PL-PRO,pp1a,Replicase polyprotein 1a,Papain-l...	SARS-CoV-2	E. coli
	Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV. PLpro is a cysteine protease located within the non-structural protein 3 (NS3) sect...
TMPK-01352	SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi) Plpro,PL2-PRO,pp1a,nsp1,Replicase polyprotein 1a,Papa	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS-CoV-2 PLpro/papain-like protease Pro...
TMPH-02364	Japanese encephalitis virus Genome polyprotein (His & SUMO)	JEV	E. coli
	Japanese encephalitis virus Genome polyprotein (His & SUMO) is expressed in E. coli.
TMPK-01384	SARS PLpro/papain-like protease Protein (His) Papain-like Protease,PL-PRO,Replicase polyprotein 1...	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS PLpro/papain-like protease Protein (...
TMPY-01500	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is A0FFY3.
TMPY-01135	Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H2N2	HEK293 Cells
	Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03451.

重组蛋白

Aminopeptidase A Protein, Human, Recombinant (His)

Cat.No: TMPY-00644

Species: Human

Expression System: Baculovirus Insect Cells

Aminopeptidase A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02896

Species: Mouse

Expression System: Baculovirus Insect Cells

Tapasin Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02177

Species: Human

Expression System: E. coli

HBV-D subtype ayw (isolate Japan/JYW796/1988) Protein X (His)

Cat.No: TMPH-00808

Species: HBV-D

Expression System: E. coli

DAPA aminotransferase Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00573

Species: E. coli

Expression System: E. coli

Turnip mosaic virus (TuMV) (strain Japanese) Genome polyprotein (His & Myc)

Cat.No: TMPH-03650

Species: TuMV

Expression System: E. coli

Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-01622

Species: H5N1

Expression System: HEK293 Cells

Papain Protein, Carica papaya, Recombinant (His)

Cat.No: TMPH-00347

Species: Carica papaya

Expression System: E. coli

Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-00567

Species: H2N2

Expression System: HEK293 Cells

Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA1 Protein (His), Biotinylated

Cat.No: TMPY-06031

Species: H5N1

Expression System: HEK293 Cells

SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His)

Cat.No: TMPY-05682

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV (strain WH20) Plpro/papain-like protease (His)

Cat.No: TMPY-04894

Species: SARS

Expression System: E. coli

Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA Protein (His), Biotinylated

Cat.No: TMPY-06038

Species: H5N1

Expression System: HEK293 Cells

SapA Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00714

Species: E. coli

Expression System: E. coli

Tapasin Protein, Human, Recombinant (His)

Cat.No: TMPY-00254

Species: Human

Expression System: HEK293 Cells

SARS-CoV-2 Papain-Like Protease Protein

Cat.No: TMPJ-01431

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi)

Cat.No: TMPK-01352

Species: SARS

Expression System: E. coli

Japanese encephalitis virus Genome polyprotein (His & SUMO)

Cat.No: TMPH-02364

Species: JEV

Expression System: E. coli

SARS PLpro/papain-like protease Protein (His)

Cat.No: TMPK-01384

Species: SARS

Expression System: E. coli

Influenza A H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-01500

Species: H5N1

Expression System: HEK293 Cells

Influenza A H2N2 (A/Japan/305/1957) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-01135

Species: H2N2

Expression System: HEK293 Cells

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上海市静安区江场三路238号8楼