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594

抑制剂 & 化合物

40

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0202	Sulbentine Dibenzthione,舒苯汀	Antifungal	Microbiology/Virology
	Sulbentine (Dibenzthione) 是一种具有抑菌和杀真菌活性的唑类抗真菌试剂，可作为局部抗菌试剂。
T5051	Isopropamide Iodide	AChR	Neuroscience
	Isopropamide iodide 是长效季铵盐抗胆碱能药物。它用于研究消化性溃疡和其他胃肠道疾病，尤其是胃酸过多和运动过度。
T4985	Neticonazole Hydrochloride	Antifungal	Microbiology/Virology
	Neticonazole hydrochloride 是一种咪唑衍生物，具有抗感染和抗癌作用。它也是一种长效抗真菌剂。
T19862	Voxilaprevir 维昔普维,伏西瑞韦	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Voxilaprevir 是丙型肝炎病毒非结构蛋白 3/4A 蛋白酶的抑制剂，具有抗病毒活性。它抑制基因型 1b 和 3a 野生型 NS3 蛋白酶的 Ki 值分别为 0.038 nM 和 0.066 nM。
T0388	Cilnidipine FRC-8653,西尼地平	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cilnidipine (FRC-8653) 是二氢吡啶类Ca2+通道阻断剂，可作用于 L 和 N 型 Ca2+通道，具有抗高血压活性。
T1674	Nateglinide 那格列奈,A4166,Senaglinide	Potassium Channel; Proteasome; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome; Ubiquitination
	Nateglinide (Senaglinide) 是 D-苯丙氨酸的一种衍生物，是口服有效的、短效促胰岛素释放化合物，也是 DPP IV 抑制剂。 Nateglinide 抑制胰岛 β 细胞中 ATP 敏感的 K+通道。Nateglinide 在 2 型糖尿病中具有研究价值。
T7943	Fluphenazine decanoate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fluphenazine decanoate 是一种高度连续的多巴胺 D2受体阻滞剂，是一种长效吩噻嗪抗精神病药，用于精神分裂症的研究。
T3716	Rolapitant 罗拉吡坦,SCH619734,罗拉匹坦	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Rolapitant (SCH619734) 是一种高效选择性具有口服活性的神经激肽 1 受体抑制剂，Ki 值为0.66 nM。
T6504	Flupirtine maleate Katadolon maleate,氟吡啶马来酸,马来酸氟吡汀	Potassium Channel; NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Flupirtine maleate (Katadolon maleate) 是可透过血脑屏障的、具有口服活性的非阿片类化合物。它是间接 NMDAR 拮抗剂，可用于缓解疼痛的研究，具有神经保护特性。
T5159	Olodaterol hydrochloride BI-1744 HCl,盐酸奥达特罗,BI 1744 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Olodaterol hydrochloride (BI-1744 HCl) 是一种长效的、选择性 β2-adrenoceptor(β2-AR) 激动剂 (EC50=0.1 nM；pKi= 9.14 for human β2-adrenoceptor)，可用于慢性阻塞性肺疾病 (COPD) 和肺纤维化的研究。
T20720	Norethisterone enanthate NSC 9564,Norethindrone enanthate,LG-202,LG202,NSC9564,LG 202,炔诺酮庚酸酯,NSC-9564	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Norethisterone enanthate (NSC-9564) 是一种口服有效的长效的孕激素。
T0373	Erlotinib OSI-744,NSC 718781,CP358774,埃罗替尼,R1415	EGFR; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Erlotinib (NSC-718781) 是一种直接作用的EGFR 酪氨酸激酶抑制剂，用于治疗非小细胞肺癌，对人 EGFR 的IC50为 2 nM。它可降低完整肿瘤细胞的 EGFR 自磷酸化，IC50为 20 nM。
T2390	Cevimeline hydrochloride hemihydrate	AChR	Neuroscience
	Cevimeline hydrochloride hemihydrate 是乙酰胆碱的奎尼丁衍生物，也是选择性的和口服活性的毒蕈碱型M1和M3受体激动剂。它可穿过血脑屏障，刺激唾液腺分泌，用作口干症的催涎剂。
T31716	Etidocaine Hydrochloride W-19053,Duranest,W19053,W 19053	Sodium Channel	Membrane transporter/Ion channel
	Etidocaine Hydrochloride (W19053) 是一种长效麻醉剂和电压门控钠通道阻滞剂。
T0364L	Dibucaine hydrochloride Cinchocaine HCl,Dibucaine HCl,盐酸地布卡因,Cinchocaine hydrochloride	Sodium Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	Dibucaine hydrochloride (Cinchocaine hydrochloride) 是钠通道抑制剂和有效的 SChE 抑制剂。
T33386	Milveterol HCl Milveterol,GSK-159797,GSK 159797,GSK159797	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Milveterol HCl 是一种长效β（2）-肾上腺素能受体激动剂，可用于治疗慢性阻塞性肺病（COPD）。
T4548	Procaterol hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Procaterol hydrochloride 用于治疗哮喘的短效β2-肾上腺素受体激动剂。
T0749	Succinylsulfathiazole 琥珀酰磺胺噻唑,Succinylsulphathiazole	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Succinylsulfathiazole (Succinylsulphathiazole) 是一种超长效磺胺类药物。
T4499	Mequitazine Metaplexan,Virginan,Primalan,LM-209,美喹他嗪	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Mequitazine (Virginan) 是一种有效的、非镇静剂和长效组胺 H1 拮抗剂。
T4551	Acrivastine Acrivastin,阿伐斯汀,BW825C,Semprex	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Acrivastine (Acrivastin) 是一种短效组胺 1 受体拮抗剂，可用于研究过敏性鼻炎。
T68087	Inaperisone	Others	Others
	Inaperisone 是一种新型的中枢作用的肌肉松弛剂，对排尿反射有抑制作用。Inaperisone 可能通过间接作用于脑干的GABAB 受体来抑制排尿反射。
T6876	Liraglutide 利拉鲁肽,Liraglutidum,利拉糖肽,Victoza,Liraglutida,NN2211	Glucagon Receptor	GPCR/G Protein
	Liraglutide (Liraglutida) 是胰高血糖素样肽-1 受体激动剂，用于 2 型糖尿病的研究。
T28360	PF-00489791 PF-4634817,PF 4634817,PF00489791,PF 00489791,PF4634817	PDE	Metabolism
	PF-00489791 (PF4634817) 是一种长效 PDE5 抑制剂，具有降血压活性，可用于研究糖尿病肾病。
T11235	Estradiol 3-sulfamate 雌二醇 3-氨基磺酸,ES-J 995,E2MATE,BLE 00084	Others	Others
	.Estradiol 3-sulfamate inhibits estrone sulfatase with an IC50 of 251 nM and a Ki of 133 nM. Estradiol 3-sulfamate is a potent, long-acting, and orally active steroid sulfatase inhibitor.
T37069	Pyribencarb 吡菌苯威,ZINC43065336	Antifungal	Microbiology/Virology
	Pyribencarb (), a benzylcarbamate-type fungicide, exhibits broad-spectrum activity against various plant pathogenic fungi. Acting as a potent Qo inhibitor of cytochrome b, Pyribencarb demonstrates particular efficacy against Botrytis cinerea and Sclerotinia sclerotiorum.
T26939	Cadralazine ISF 2469,卡屈嗪,ISF-2469,ISF2469	Others	Others
	Cadralazine (ISF 2469) 是一种外周小动脉血管扩张剂，可用于作为抗高血压药物的研究。
T1239	Indacaterol maleate 马来酸茚达特罗,QAB149	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Indacaterol maleate (QAB149) 是一种超长效的 β-肾上腺素受体激动剂。
T34146	Propanidid FBA 1420,Epontol,Sombrevin,Fabontal,Fabantol	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Propanidid (Sombrevin) 是一种 γ-氨基丁酸 A 型受体 (GABAA) 激动剂，也是一种可快速发挥作用的静脉注射麻醉剂,可以降低动脉血压。
T0747	Sulfathiazole 2-Sulfanilamidothiazole,磺胺噻唑	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Sulfathiazole (2-Sulfanilamidothiazole) 是一种短效磺胺类抗生素。
T0015	Mephenesin Cresoxydiol,甲酚甘油醚,Memphenesin,Mephedan,Decontractyl	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Mephenesin (Cresoxydiol) 是 NMDA 受体拮抗剂，也是中枢性肌松弛剂。
T1629	Rifapentine MDL473,Rifapentina,Rifapentinum,DL 473,利福喷丁,Priftin,Cyclopentylrifampicin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifapentine (Rifapentinum) 是可用于肺结核的抗生素。
TP1351L	Kemptide TFA	Others	Others
	Kemptide TFA (65189-71-1 free base) 是一种合成七肽，可作为 cAMP 依赖性蛋白激酶 (PK) 的底物。
T23969	DCAI	Others	Others
	DCAI 是一种核苷酸交换和核苷酸释放的抑制剂，通过与 Ras-SOS 界面附近的口袋结合而起作用。
T2150	Guanfacine hydrochloride 盐酸胍法辛,Tenex,Intuniv,Guanfacine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Guanfacine hydrochloride (Intuniv) 是一种 α2A 肾上腺素受体激动剂，Kd=31 nM，具有抗高血压作用。
T6992	Sulfadiazine sodium Sulfadiazin-natrium,磺胺嘧啶钠,Sodium sulfadiazine	Others; Antibacterial; Antibiotic; Parasite	Microbiology/Virology; Others
	Sulfadiazine sodium (Sulfadiazin-natrium) 是一种磺胺类抗生素具有抗疟活性，可研究弓形虫病。
T0504	Cyclandelate 安脉生,BS 572,环扁桃酯,3,5,5-Trimethylcyclohexyl mandelate	Acyltransferase	Metabolism
	Cyclandelate (BS 572) 是直接作用的平滑肌松弛剂，用于扩张血管。
T19858	Brodimoprim	DHFR; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Brodimoprim 是甲氧苄啶的一种类似物，是口服有效的二氢叶酸还原酶抑制剂，对广谱革兰氏阴性和革兰氏阳性细菌具有高度的抑制作用。
T3288	Sulfisomidin Sulfisomidine,Sulfadimetine,磺胺二甲基异嘧啶,sulfamethin,磺胺二甲异嘧啶,Sulfaisodimidine	Antibacterial; Antibiotic	Microbiology/Virology
	Sulfisomidin (Sulfaisodimidine) 是一种具有口服活性的短效磺酰胺类抗菌剂。它可研究下尿路感染。
T20435L	Leuphasyl TFA	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Leuphasyl TFA 是一种酰胺肽，一种 δ-阿片受体激动剂，是一种抗降解的长效 Leu-脑啡肽类似物，用于研究 δ 阿片受体的信号通路。它是一种有效的长效 Leu-脑啡肽类似物，可抵抗酶促降解。
T0127	Glimepiride Glimperide,HOE-490,格列美脲	Potassium Channel	Membrane transporter/Ion channel
	Glimepiride (HOE-490) 是一种中长效的磺酰脲类抗糖尿病化合物，其 ED50=182 μg/k。
T16433	Pancopride LAS 30451	5-HT Receptor	GPCR/G Protein; Neuroscience
	Pancopride（LAS 30451）是一种可口服的新型有长效的选择性 5-HT3 受体拮抗剂，可阻断氮芥和达卡巴嗪诱导的呕吐。
T4119	Octreotide Acetate 醋酸奥曲肽,SMS 201995,Longastatin,Sandostatin,SMS 201-995 (acetate)	Somatostatin	GPCR/G Protein
	Octreotide Acetate (Sandostatin) 是一种长期有效的合成生长抑素八肽类似物，可抑制生长激素的分泌。
T7118	Dimethocaine 二甲卡因,Larocaine	Others; Dopamine Receptor	GPCR/G Protein; Neuroscience; Others
	Dimethocaine (Larocaine) 是一种局部麻醉剂，也对中枢神经系统起多巴胺再摄取抑制剂的作用。
T0748	Sulfameter 5-Methoxysulfadiazine,Sulfametoxydiazine,磺胺对甲氧嘧啶	DHFR; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Sulfameter (Sulfametoxydiazine) 是一种长效磺胺类抗生素，具有抗菌活性。它可研究尿路感染和麻风病。
T30785	Cefacetrile Cefacetrilum,Cefacetrilo,Celospor,Cephacetrile,Cefacetril	Antibiotic	Microbiology/Virology
	Cefacetrile (Cephacetrile) 是一种广谱的头孢类抗生素，具有抗菌活性，可用于研究革兰氏菌感染，作用与头孢噻吩作用。
T0651	N-Phenylbenzylamine Benzylaniline,Benzenemethanamine,N-苄基苯胺	Microtubule Associated	Cytoskeletal Signaling
	N-Phenylbenzylamine (Benzenemethanamine) 作为潜在的细胞毒性和抗有丝分裂剂，通过抑制微管蛋白聚合起作用。
T22508	3-CPMT Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1	Dopamine Receptor	GPCR/G Protein; Neuroscience
	3-CPMT (FC-1) 是一种多巴胺摄取抑制剂和一种有效的长效抗组胺剂。
T9124	Laninamivir octanoate 辛酸拉尼米韦,CS-8958	Influenza Virus	Microbiology/Virology
	Laninamivir octanoate (CS-8958) 是一种长效流感神经氨酸酶抑制剂，是Laninamivir 的前药，具有优异的抗流感病毒活性。
T6566	Levobupivacaine hydrochloride Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,盐酸左布比卡因,(S)-(-)-Bupivacaine monohydrochloride	Sodium Channel	Membrane transporter/Ion channel
	Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) 是有效的钠通道阻滞剂。
T1028	Moxonidine 莫索尼定,BDF5895,莫索尼啶	Imidazoline Receptor	Neuroscience
	Moxonidine (BDF5895) 是咪唑啉受体亚型 1 的选择性激动剂，用作抗高血压药物。

化合物

Cat.No: T0202

Synonym: Dibenzthione,舒苯汀

Target: Antifungal

Isopropamide Iodide

Cat.No: T5051

Target: AChR

Neticonazole Hydrochloride

Cat.No: T4985

Target: Antifungal

Cat.No: T19862

Synonym: 维昔普维,伏西瑞韦

Target: HCV Protease

Cat.No: T0388

Synonym: FRC-8653,西尼地平

Target: Calcium Channel

Cat.No: T1674

Synonym: 那格列奈,A4166,Senaglinide

Target: Potassium Channel, Proteasome, PPAR

Fluphenazine decanoate

Cat.No: T7943

Target: Dopamine Receptor

Cat.No: T3716

Synonym: 罗拉吡坦,SCH619734,罗拉匹坦

Target: Neurokinin receptor

Flupirtine maleate

Cat.No: T6504

Synonym: Katadolon maleate,氟吡啶马来酸,马来酸氟吡汀

Target: Potassium Channel, NMDAR, iGluR

Olodaterol hydrochloride

Cat.No: T5159

Synonym: BI-1744 HCl,盐酸奥达特罗,BI 1744 hydrochloride

Target: Adrenergic Receptor

Norethisterone enanthate

Cat.No: T20720

Synonym: NSC 9564,Norethindrone enanthate,LG-202,LG202,NSC9564,LG 202,炔诺酮庚酸酯,NSC-9564

Target: Estrogen/progestogen Receptor

Cat.No: T0373

Synonym: OSI-744,NSC 718781,CP358774,埃罗替尼,R1415

Target: EGFR, Autophagy

Cevimeline hydrochloride hemihydrate

Cat.No: T2390

Target: AChR

Etidocaine Hydrochloride

Cat.No: T31716

Synonym: W-19053,Duranest,W19053,W 19053

Target: Sodium Channel

Dibucaine hydrochloride

Cat.No: T0364L

Synonym: Cinchocaine HCl,Dibucaine HCl,盐酸地布卡因,Cinchocaine hydrochloride

Target: Sodium Channel, AChR

Cat.No: T33386

Synonym: Milveterol,GSK-159797,GSK 159797,GSK159797

Target: Adrenergic Receptor

Procaterol hydrochloride

Cat.No: T4548

Target: Adrenergic Receptor

Succinylsulfathiazole

Cat.No: T0749

Synonym: 琥珀酰磺胺噻唑,Succinylsulphathiazole

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T4499

Synonym: Metaplexan,Virginan,Primalan,LM-209,美喹他嗪

Target: Histamine Receptor

Cat.No: T4551

Synonym: Acrivastin,阿伐斯汀,BW825C,Semprex

Target: Histamine Receptor

Cat.No: T68087

Target: Others

Cat.No: T6876

Synonym: 利拉鲁肽,Liraglutidum,利拉糖肽,Victoza,Liraglutida,NN2211

Target: Glucagon Receptor

Cat.No: T28360

Synonym: PF-4634817,PF 4634817,PF00489791,PF 00489791,PF4634817

Target: PDE

Estradiol 3-sulfamate

Cat.No: T11235

Synonym: 雌二醇 3-氨基磺酸,ES-J 995,E2MATE,BLE 00084

Target: Others

Cat.No: T37069

Synonym: 吡菌苯威,ZINC43065336

Target: Antifungal

Cat.No: T26939

Synonym: ISF 2469,卡屈嗪,ISF-2469,ISF2469

Target: Others

Indacaterol maleate

Cat.No: T1239

Synonym: 马来酸茚达特罗,QAB149

Target: Adrenergic Receptor

Cat.No: T34146

Synonym: FBA 1420,Epontol,Sombrevin,Fabontal,Fabantol

Target: GABA Receptor

Cat.No: T0747

Synonym: 2-Sulfanilamidothiazole,磺胺噻唑

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T0015

Synonym: Cresoxydiol,甲酚甘油醚,Memphenesin,Mephedan,Decontractyl

Target: NMDAR, iGluR

Cat.No: T1629

Synonym: MDL473,Rifapentina,Rifapentinum,DL 473,利福喷丁,Priftin,Cyclopentylrifampicin

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: TP1351L

Target: Others

Cat.No: T23969

Target: Others

Guanfacine hydrochloride

Cat.No: T2150

Synonym: 盐酸胍法辛,Tenex,Intuniv,Guanfacine

Target: Adrenergic Receptor

Sulfadiazine sodium

Cat.No: T6992

Synonym: Sulfadiazin-natrium,磺胺嘧啶钠,Sodium sulfadiazine

Target: Others, Antibacterial, Antibiotic, Parasite

Cat.No: T0504

Synonym: 安脉生,BS 572,环扁桃酯,3,5,5-Trimethylcyclohexyl mandelate

Target: Acyltransferase

Cat.No: T19858

Target: DHFR, Antibacterial

Cat.No: T3288

Synonym: Sulfisomidine,Sulfadimetine,磺胺二甲基异嘧啶,sulfamethin,磺胺二甲异嘧啶,Sulfaisodimidine

Target: Antibacterial, Antibiotic

Cat.No: T20435L

Target: Opioid Receptor

Cat.No: T0127

Synonym: Glimperide,HOE-490,格列美脲

Target: Potassium Channel

Cat.No: T16433

Synonym: LAS 30451

Target: 5-HT Receptor

Octreotide Acetate

Cat.No: T4119

Synonym: 醋酸奥曲肽,SMS 201995,Longastatin,Sandostatin,SMS 201-995 (acetate)

Target: Somatostatin

Cat.No: T7118

Synonym: 二甲卡因,Larocaine

Target: Others, Dopamine Receptor

Cat.No: T0748

Synonym: 5-Methoxysulfadiazine,Sulfametoxydiazine,磺胺对甲氧嘧啶

Target: DHFR, Antibacterial, Antibiotic

Cat.No: T30785

Synonym: Cefacetrilum,Cefacetrilo,Celospor,Cephacetrile,Cefacetril

Target: Antibiotic

N-Phenylbenzylamine

Cat.No: T0651

Synonym: Benzylaniline,Benzenemethanamine,N-苄基苯胺

Target: Microtubule Associated

Cat.No: T22508

Synonym: Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1

Target: Dopamine Receptor

Laninamivir octanoate

Cat.No: T9124

Synonym: 辛酸拉尼米韦,CS-8958

Target: Influenza Virus

Levobupivacaine hydrochloride

Cat.No: T6566

Synonym: Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,盐酸左布比卡因,(S)-(-)-Bupivacaine monohydrochloride

Target: Sodium Channel

Cat.No: T1028

Synonym: 莫索尼定,BDF5895,莫索尼啶

Target: Imidazoline Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T3327	Artemotil SM-227,β-Arteether,Beta-Arteether,蒿乙醚,Arteether,(+)-Arteether	CXCR; CCR; Parasite	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology
	Artemotil (SM-227) 是一种新型的速效抗疟药，可研究耐Plasmodium falciparum 的恶性疟原虫疟疾，IC50值为 1.61 nM。
T0419	Testosterone propionate	Others; Androgen Receptor; Transferase	Endocrinology/Hormones; Metabolism; Others
	Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels.
TN1927	Methyl Kakuol 1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one	TRP/TRPV Channel	Membrane transporter/Ion channel
	Methyl Kakuol 是 TRPA1 的激动剂，EC50 为 0.27 µM，可用于作为 MBST 成分 Asiasari Radix 的活性成分的研究。
TN1128	Bruceine E	Others	Others
	Bruceine E 是从 B. javanica 种子中分离得到的，具有降血糖作用。 Bruceine E 可用于作为胰岛素促分泌剂的研究。
TN1372	Alpha-Amyrin alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol,α-香树脂醇	P450; Serine Protease; ROS	Immunology/Inflammation; Metabolism; Proteases/Proteasome
	Alpha-Amyrin (alpha-Amyrine) 是一种具有抗肿瘤作用的胰蛋白酶和糜蛋白酶抑制剂。 alpha-Amyrin 可用于作为肝调节剂的研究。
T0268	Lobeline hydrochloride 盐酸洛贝林,α-Lobeline hydrochloride,L-Lobeline hydrochloride	AChR	Neuroscience
	Lobeline hydrochloride (α-Lobeline hydrochloride) 是一种烟碱样受体激动剂，是神经元烟碱受体α3β2和α4β2拮抗剂。
TN2148	Retusin 5-Hydroxy-3,7,3',4'-tetramethoxyflavone,Quercetin-3,7,3',4'-tetramethyl ether	ATPase; Free radical scavengers; Tyrosinase	Membrane transporter/Ion channel; oxidation-reduction; Proteases/Proteasome
	Retusin 是从 Talinum triangulare 的叶子中提取的。 Retusin Retusin 可用于作为芽前和芽后除草剂的研究。
T2796	Coenzyme Q10 Ubiquinone-10,辅酶Q10,CoQ10	Ferroptosis; Reactive Oxygen Species; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Coenzyme Q10 (CoQ10)是来自藤仓赤霉菌的一种天然产物，在线粒体呼吸链中充当电子载体。
T0086	Galanthamine hydrobromide Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏	AChR; AChE	Neuroscience
	Galanthamine hydrobromide (Galantamine hydrobromide) 是一种长效的中枢活性 AChE 抑制剂，IC50为 410 nM。它是神经元烟碱型 ACh 受体的变构增强剂，IC50值为 0.35 µM，可用于阿尔茨海默症的研究。
T2983	3,4,5-Trimethoxycinnamic acid 3-(3,4,5-Trimethoxyphenyl)acrylic Acid,O-Methylsinapic acid,3,4,5-三甲氧基肉桂酸	GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) 是从远志中分离得到的苯丙素类天然产物，可延长动物的睡眠时间，增强 GAD65 和 GABAA 受体 γ 亚基，具有抗应激作用。
T3S2007	MRE-269 3-氧代-12-烯-28-乌苏酸,MRE 269,ACT-333679,MRE269	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	MRE-269 (ACT-333679) 是一种口服的长效前列环素受体激动剂前药，是 Selexipag 的活性代谢物，用于治疗肺动脉高压。
T0965	Histamine Ergamine,组胺	5-HT Receptor; Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Histamine (Ergamine) 是通过组胺的酶促脱羧衍生的胺。它是一种强大的胃分泌兴奋剂、支气管平滑肌的收缩剂、血管扩张剂以及中枢作用的神经递质。
T0012	Cinchonine LA40221,(8R,9S)-Cinchonine,奎宁树,辛可宁	Apoptosis; P-gp; Parasite	Apoptosis; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Cinchonine (LA40221) 是金鸡纳树皮中的一种天然产物。它可激活内质网应激诱导的人肝癌细胞凋亡。它是一种酰胺类局部麻醉剂。
T1261	Medroxyprogesterone Acetate Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,醋酸甲羟孕酮,Farlutin,安宫黄体酮,Medroxyprogesterone (acetate)	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; Androgen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; Others
	Medroxyprogesterone Acetate (Farlutin) 是广泛使用的合成类固醇，与雄激素，孕酮及糖皮质激素受体均有作用。
T11680	Isoasatone A	P450	Metabolism
	Isoasatone A 是一种具有抗虫作用的天然产物，分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶，产生抗S. litura 作用。
T6534	Histamine dihydrochloride 组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl	Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Histamine dihydrochloride (Ceplene) 是 Histamine 的二盐酸形式。Histamine 是一种有机氮化合物，是一种强效的胃分泌兴奋剂，支气管平滑肌收缩剂，血管舒张剂，也是一种中枢作用的神经递质。
TCS1704	Artemitin 艾黄素,Artemetin,Artemisetin,Erianthin	Antioxidant	oxidation-reduction
	Artemitin (Erianthin) 是一种存在于翼齿六棱菊中的天然黄酮，具有抗氧化、抗炎、抗病毒活性。
TN1202	(-)-α-Pinene 左旋-α-蒎烯,左旋-alpha-蒎烯,(1S)-(-)-Alpha-Pinene	Virus Protease; GABA Receptor; Endogenous Metabolite; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) 是一种单萜类化合物，通过延长 GABAergic 突触传递、作为 GABAA-BZD 受体的部分调节剂并直接与 GABAA 受体的 BZD 结合位点结合来增强 NREMS 的数量而不影响 NREMS 的强度。
T2S2108	Coixol 薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA	Others; Antibacterial	Microbiology/Virology; Others
	Coixol (MBOA) 是一种从薏苡仁中提取的多酚，有抗菌和抗肿瘤作用。
TN1413	Atranorin 荔枝素，巴美灵,荔枝素	Endogenous Metabolite; NO Synthase; Ras	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism
	Atranorin 是地衣的次生代谢产物，具有显着的抗伤害、抗炎和氧化还原活性，对 H(2)O(2) 诱导的氧化应激下的细胞具有细胞保护作用。
T8183	Deslanoside 洋地黄,去乙酰西地兰,Desacetyllanatoside C,Deacetyllanatoside C	ATPase; Drug Metabolite	Membrane transporter/Ion channel; Metabolism
	Deslanoside (Desacetyllanatoside C) 是一种快速作用的强心苷，可抑制Na-K-ATPase 膜泵，导致细胞内钠和钙浓度增加。它用于研究充血性心力衰竭和因折返机制引起的室上性心律失常，并在研究慢性心房颤动时控制心室率。
T3392	Sinapine thiocyanate	P-gp; AChE	Membrane transporter/Ion channel; Neuroscience
	Sinapine thiocyanate 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
T2520	Desloratadine Sch34117,地氯雷他定,NSC 675447	Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Desloratadine (Sch34117) 是非镇静H1抗组胺药 Loratadine 的主要口服代谢物，可减少对支气管平滑肌、毛细血管和胃肠道平滑肌中 H1 受体的典型组胺能作用，包括血管舒张、支气管收缩、血管通透性增加、疼痛、瘙痒和胃肠道平滑肌的痉挛性收缩。它是一种选择性H1受体拮抗剂，具有抗过敏和抗炎活性。
T3929	Kaurenoic acid Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid	Others	Others
	Kaurenoic acid (kaurenoate) 是一种二萜，来源于 Sphagneticola trilobata 中，可以抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路，并抑制炎症疼痛。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
T5287	N-Acetyl-L-aspartic acid AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-L-aspartic acid (AC-ASP-OH) 是天冬氨酸的衍生物，是由氨基酸天冬氨酸和乙酰辅酶 A 在神经元中合成的。
T31911	Ganodermic acid S Ganoderic acid R
	Ganodermic acid S, as a membrane acting agent isolated from the fungus Ganoderma lucidum, exerts multiple effects on human platelet function.
TN2120	Quassin	Others; Antifection	Microbiology/Virology; Others
	Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion.
TN2306	Wilfordine	ATPase; Potassium Channel; Sodium Channel	Membrane transporter/Ion channel
	Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
TN6565	Maculosidin
	Maculosidine affect the PS I electron acceptors on leaf discs, it can inhibit ATP synthesis, basal, phosphorylating and uncoupled electron transport acting as Hill reaction inhibitors on spinach chloroplasts.
TN2176	Sanggenol A	Influenza Virus; Antifection	Microbiology/Virology
	Sanggenol A 抑制甲型流感病毒和肺炎球菌神经氨酸酶，因此可作为双重作用的抗感染试剂。
T38497	(-)-Taxifolin (-)-二氢槲皮素,(-)-Dihydroquercetin
	(-)-Taxifolin is the less active enantiomer of Taxifolin, demonstrating vital anti-tyrosinase activity and notable inhibition against collagenase (IC50 = 193.3 μM). It is valued as an essential natural compound showing antifibrotic potential, while also acting as a capable free radical scavenger and possessing antioxidant capacity.
TN2050	Peonidin-3-O-glucoside chloride Peonidin 3-Glucoside Chloride	Free radical scavengers	oxidation-reduction
	Peonidin-3-O-glucoside chloride (Peonidin 3-Glucoside Chloride) 是一种具有自由基清除活性的花青素，可用于作为胰岛素促分泌剂的研究。
TN2222	Sotetsuflavone	Others	Others
	Sotetsuflavone is a potent inhibitor of DENV-NS5 RdRp (Dengue virus NS5 RNA-dependent RNA polymerase) with an IC50 of 0.16 μM, is the most active compound of this series.
TN3802	Dehydrodiconiferyl alcohol	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Dehydrodiconiferyl alcohol （DHCA）是一种从葫芦中分离出来的木脂素，通过作为雌激素受体激动剂抑制破骨细胞分化和卵巢切除术诱导的骨质流失。
T72459	3-Oxo-hop-22(29)-ene
	3-Oxo-hop-22(29)-ene 是一种yeast α-glucosidase 抑制剂。3-Oxo-hop-22(29)-ene 具有中等的抗克氏锥虫和抗墨西哥利什曼原虫活性。3-Oxo-hop-22(29)-ene 具有微弱的抗炎活性。
T73812	Phosphatidylinositol 4,5-bisphosphate
	Phosphatidylinositol 4,5-bisphosphate（L-alpha-Phosphatidylinositol-4,5-bisphosphate）为细胞膜磷脂成分，主要作为磷脂酶C（PLC）与磷酸肌醇3-激酶（PI3K）的底物，充当重要信使。
TN4185	Hautriwaic acid
	Hautriwaic acid shows anti-inflammatory activity in 12-O-tetradecanoylphorbol 13-acetate (TPA) mice ear edema models, it diminishes the joint edema induced by this mixture of polysaccharides (carrageenan), possibly by acting as immunomodulator of the infl
TN5280	(-)-Zeylenol Zeylenol	Apoptosis	Apoptosis
	(-)-Zeylenol (Zeylenol) 是一种从 Uvaria grandiflora 的茎中提取的天然产物，具有抗炎、拒食和抗肿瘤生物活性，通过抑制多种炎症介质的合成或释放发挥作用。 zezelenol 对油菜根系生长有抑制作用，具有诱导人乳腺癌 MDA-MB231细胞凋亡的潜力。
TC0022	Desoxypeganine Deoxypeganine	AChE	Neuroscience
	Desoxypeganine (Deoxypeganine) 是胆碱酯酶的抑制剂。它优先作用于丁酰胆碱酯酶，作为单胺氧化酶 A 而不是单胺氧化酶 B 的选择性抑制剂。它在酒精滥用的药理学治疗中的潜在用途，以减少酒精滥用者的渴望和抑郁，并且也可能有用作为戒烟辅助。

天然产物

Cat.No: T3327

Synonym: SM-227,β-Arteether,Beta-Arteether,蒿乙醚,Arteether,(+)-Arteether

Target: CXCR, CCR, Parasite

Testosterone propionate

Cat.No: T0419

Target: Others, Androgen Receptor, Transferase

Cat.No: TN1927

Synonym: 1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one

Target: TRP/TRPV Channel

Cat.No: TN1128

Target: Others

Cat.No: TN1372

Synonym: alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol,α-香树脂醇

Target: P450, Serine Protease, ROS

Lobeline hydrochloride

Cat.No: T0268

Synonym: 盐酸洛贝林,α-Lobeline hydrochloride,L-Lobeline hydrochloride

Target: AChR

Cat.No: TN2148

Synonym: 5-Hydroxy-3,7,3',4'-tetramethoxyflavone,Quercetin-3,7,3',4'-tetramethyl ether

Target: ATPase, Free radical scavengers, Tyrosinase

Cat.No: T2796

Synonym: Ubiquinone-10,辅酶Q10,CoQ10

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite

Galanthamine hydrobromide

Cat.No: T0086

Synonym: Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏

Target: AChR, AChE

3,4,5-Trimethoxycinnamic acid

Cat.No: T2983

Synonym: 3-(3,4,5-Trimethoxyphenyl)acrylic Acid,O-Methylsinapic acid,3,4,5-三甲氧基肉桂酸

Target: GABA Receptor, Endogenous Metabolite

Cat.No: T3S2007

Synonym: 3-氧代-12-烯-28-乌苏酸,MRE 269,ACT-333679,MRE269

Target: Prostaglandin Receptor

Cat.No: T0965

Synonym: Ergamine,组胺

Target: 5-HT Receptor, Endogenous Metabolite, Histamine Receptor

Cat.No: T0012

Synonym: LA40221,(8R,9S)-Cinchonine,奎宁树,辛可宁

Target: Apoptosis, P-gp, Parasite

Medroxyprogesterone Acetate

Cat.No: T1261

Synonym: Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,醋酸甲羟孕酮,Farlutin,安宫黄体酮,Medroxyprogesterone (acetate)

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, Androgen Receptor, Endogenous Metabolite

Cat.No: T11680

Target: P450

Histamine dihydrochloride

Cat.No: T6534

Synonym: 组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl

Target: Endogenous Metabolite, Histamine Receptor

Cat.No: TCS1704

Synonym: 艾黄素,Artemetin,Artemisetin,Erianthin

Target: Antioxidant

Cat.No: TN1202

Synonym: 左旋-α-蒎烯,左旋-alpha-蒎烯,(1S)-(-)-Alpha-Pinene

Target: Virus Protease, GABA Receptor, Endogenous Metabolite, Antibacterial

Cat.No: T2S2108

Synonym: 薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA

Target: Others, Antibacterial

Cat.No: TN1413

Synonym: 荔枝素，巴美灵,荔枝素

Target: Endogenous Metabolite, NO Synthase, Ras

Cat.No: T8183

Synonym: 洋地黄,去乙酰西地兰,Desacetyllanatoside C,Deacetyllanatoside C

Target: ATPase, Drug Metabolite

Sinapine thiocyanate

Cat.No: T3392

Target: P-gp, AChE

Cat.No: T2520

Synonym: Sch34117,地氯雷他定,NSC 675447

Target: Endogenous Metabolite, Histamine Receptor

Cat.No: T3929

Synonym: Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid

Target: Others

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

N-Acetyl-L-aspartic acid

Cat.No: T5287

Synonym: AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸

Target: Others, Endogenous Metabolite

Ganodermic acid S

Cat.No: T31911

Synonym: Ganoderic acid R

Cat.No: TN2120

Target: Others, Antifection

Cat.No: TN2306

Target: ATPase, Potassium Channel, Sodium Channel

Cat.No: TN6565

Cat.No: TN2176

Target: Influenza Virus, Antifection

Cat.No: T38497

Synonym: (-)-二氢槲皮素,(-)-Dihydroquercetin

Peonidin-3-O-glucoside chloride

Cat.No: TN2050

Synonym: Peonidin 3-Glucoside Chloride

Target: Free radical scavengers

Cat.No: TN2222

Target: Others

Dehydrodiconiferyl alcohol

Cat.No: TN3802

Target: Estrogen/progestogen Receptor

3-Oxo-hop-22(29)-ene

Cat.No: T72459

Phosphatidylinositol 4,5-bisphosphate

Cat.No: T73812

Hautriwaic acid

Cat.No: TN4185

Cat.No: TN5280

Synonym: Zeylenol

Target: Apoptosis

Cat.No: TC0022

Synonym: Deoxypeganine

Target: AChE

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