360
98
2
13
442
Cat. No. | Product Name | ||
---|---|---|---|
L6600 | 胃肠炎天然产物库 | 219 compounds | |
219 种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L9700 | 内质网应激化合物库 | 193 compounds | |
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0090 |
Mag Beads Streptavidin (1 μm)
链霉亲和素磁珠 (1 μm) |
||
C0051 |
Penicillin-Streptomycin Solution (100×), Sterile
青霉素-链霉素双抗溶液(100×),灭菌 |
Solution in bottle | |
C0045 |
RIPA Lysis Buffer (Strong)
RIPA裂解液(强) |
Solution in bottle | |
C0092 |
Mag Beads Streptavidin (2.8 μm)
链霉亲和素磁珠 (2.8 μm) |
||
CL0113 |
ER stress pathway inhibitor/inducer kit
ER stress pathway inhibitor/inducer kit |
||
C0091 |
Mag Beads Streptavidin (2 μm)
链霉亲和素磁珠 (2 μm) |
||
C0114 |
Magrose Beads Strep-Tactin
Strep-tag Ⅱ蛋白纯化磁珠 |
||
C0089 |
Mag Beads Streptavidin (300 nm)
链霉亲和素磁珠 (300 nm) |
||
C0093 |
Mag Beads Streptavidin (3 μm)
链霉亲和素磁珠 (3 μm) |
||
C0094 |
Mag Beads Streptavidin (5 μm)
链霉亲和素磁珠 (5 μm) |
||
C0095 |
Magrose Beads Streptavidin (Ultra-suspension)
琼脂糖链霉亲和素磁珠 |
||
C0052 |
Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile
青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌 |
Solution in bottle | |
CL0060 |
Estrogen Receptor inhibitor kit
Estrogen Receptor inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7592 |
Trifloxystrobin
CGA 279202,肟菌酯 |
Antifungal | Microbiology/Virology |
Trifloxystrobin (CGA 279202) 是一种杀菌剂,可抑制从甜菜作物中分离出的立枯病菌的生长。对大型水蚤新生儿和胚胎的 EC50 分别为 23.0 μg/L 和 1.7 μg/L。 | |||
TP2107L |
Histrelin acetate
Histrelin acetate(76712-82-8 free base),醋酸组氨瑞林 |
GNRH Receptor | GPCR/G Protein |
Histrelin acetate 是促性腺激素释放激素 (GnRH) 的九肽类似物,具有增加的效力。当存在于血流中时,它作用于称为促性腺激素的垂体特定细胞。 Histrelin 刺激这些细胞释放促黄体激素和促卵泡激素。因此,它被认为是促性腺激素释放激素激动剂或 GnRH 激动剂。 | |||
T13799 |
NQO1 substrate
|
NADPH | Metabolism |
NQO1 substrate 是一种高效的 NQO1 底物,具有潜在的抗肿瘤活性,可用于研究白血病。 | |||
T6533 |
Hexestrol
Bibenzyl,4,4'-(1,2-二乙基亚乙基)二苯酚,Hexanoestrol,meso-Hexestrol,Hexestrofen |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Hexestrol (Hexanoestrol) 是非甾体合成雌激素,对雌激素受体ERα和ERβ的Ki=均为 0.06 nM。它可增加牛的体重,也可用于雌激素缺乏引起的疾病的研究。 | |||
T11237 |
Camizestrant
Estrogen receptor antagonist 2 |
Estrogen Receptor/ERR | Endocrinology/Hormones |
Camizestrant (Estrogen receptor antagonist 2) 是一种雌激素受体拮抗剂,可用于 ER+ HER2 晚期乳腺癌的研究[1]。 | |||
T11399 |
Giredestrant
GDC-9545 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Giredestrant (GDC-9545) 是一种口服有效的、选择性的、非甾体的雌激素受体 (ER) 拮抗剂,具有抗肿瘤作用。它可以在 ER 配体结合域内与雌二醇 (Estradiol) 竞争结合并诱导构象变化。 | |||
T8761L |
[Leu15]-Gastrin I human acetate(39024-57-2 Free base)
|
||
[Leu15]-Gastrin I human acetate(39024-57-2 Free base) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T8761L。 | |||
TP2030 |
Gastrin I, human
Gastrin I (human) |
cholecystokinin | GPCR/G Protein |
Gastrin I, human (Gastrin I (human)) 是胃中产生的内源性肽,通过 CCK2 受体增加大鼠的胃蛋白酶原和酸分泌。 | |||
T0035 |
Dienestrol
Restrol,双烯雌酚,Dehydrostilbestrol,Dienoestrol,Cycladiene |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Dienestrol (Restrol) 是一种雌激素受体激动剂,是一种合成的非甾体类雌激素,用于对绝经期和绝经后症状的相关研究。 | |||
T6552 |
Istradefylline
伊曲茶碱,KW-6002 |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Istradefylline (KW-6002) 是选择性的可口服的腺苷 A2A 受体拮抗剂,可用于研究药物滥用、睡眠障碍、肝损伤、帕金森病和不安腿综合征等的治疗和基础科学的试验。 | |||
T0393 |
Anastrozole
阿那曲唑,ZD1033 |
Aromatase | Endocrinology/Hormones |
Anastrozole (ZD1033) 是芳香酶的选择性抑制剂,能够抑制胎盘芳香化酶(IC50:15 nM)。 | |||
T27287 |
Estredox
E 2CDS,E-2-CDS,IDR 90104,E-2CDS,IDR-90104,E 2 CDS |
||
Estredox, an estrogen receptor agonist, is used potentially for the treatment of vasomotor symptoms. | |||
TP1051L |
Protein Kinase C Peptide Substrate acetate
Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) |
Others | Others |
Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) 以依赖于第二信使和特定衔接蛋白的方式靶向特定细胞间隔物,以响应激活 g 蛋白偶联受体、酪氨酸激酶受体或酪氨酸激酶偶联受体的细胞外信号。 | |||
TP1705 |
Gastrin I (1-14), human
|
Others | Others |
Gastrin I (1-14), human 是人胃泌素 I 肽的 1-14 片段。其中Gastrin I 是内源性胃肠肽激素。Gastrin 是胃酸分泌的主要激素调节剂。 | |||
T9801 |
broparestrol
|
||
broparestrol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T9801,CAS号为 479-68-5。 | |||
T36802L |
Bisubstrate Inhibitor 78 HCl
Bisubstrate Inhibitor 78 HCl(2368247-39-4 Free base) |
Others | Others |
Bisubstrate Inhibitor 78 HCl 是一种 NNMT 抑制剂(IC50 = 1.41 μM),具有潜在的抗癌活性,在 100μM 时抑制HSC-2口腔癌细胞增殖。 | |||
TP1309 |
Gastric mucin
|
Antibacterial; Antibiotic | Microbiology/Virology |
Gastric mucin 是一种能保护胃肠道免受酸、蛋白酶、致病微生物和机械创伤影响的糖蛋白。 | |||
T63540 |
Astrophloxine
|
Beta Amyloid | Neuroscience |
Astrophloxine 是一种荧光成像探针,靶向反平行二聚体。Astrophloxine 能够用于检测阿尔茨海默症 (AD) 小鼠脑组织和脑脊液样本中聚集的 Aβ。 | |||
T28232 |
Oleoylestrone
Estrone 3-oleate,MP 101,MP-101,MP101 |
Antioxidant | oxidation-reduction |
Oleoylestrone (MP-101) 存在于血浆和脂肪组织中,具有潜在的抗氧化作用,可诱导大鼠体内脂肪的流失,可用于减肥。 | |||
T13675 |
Elacestrant dihydrochloride
RAD1901 dihydrochloride |
Estrogen/progestogen Receptor | Endocrinology/Hormones |
Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) 是一种具有口服活性的的选择性雌激素受体 (ER) 降解剂 (SERD),能够作用于 ERα (IC50:48 nM) 和 ERβ (IC50:870 nM)。 | |||
T1579 |
Mestranol
Devocin,Norquen,美雌醇,Menophase |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Mestranol (Devocin) 是一种雌激素受体激动剂,是一种非活性的前药,在转化为炔雌醇时具有生物活性。动物实验中,它可以与黄体酮联合使用,它可用于更年期激素或月经紊乱的研究。 | |||
TP1448L |
Astressin acetate
Astressin acetate (170809-51-5 Free base) |
CRFR | GPCR/G Protein |
Astressin acetate 是促肾上腺皮质激素释放因子 (CRF) 的拮抗剂,对 CRF 结合蛋白具有低亲和力,对克隆垂体受体具有高亲和力 (Ki = 2 nM)。 | |||
T23401 |
Strontium chloride
|
Others; CaSR | GPCR/G Protein; Others |
Strontium chloride 是钙敏感受体 (CaSR) 的激动剂,并可以直接影响 C 型神经纤维。 | |||
TP1787L |
PKG Substrate acetate(81187-14-6 free base)
|
PKA | Tyrosine Kinase/Adaptors |
PKG Substrate acetate(81187-14-6 free base) 是 cGMP 依赖性蛋白激酶 (PKG) 的选择性底物。PKG Substrate 是蛋白激酶 G (PKG) 的选择性底物,PKG Iα (Km = 59 µM) 优于 PKG II (Km = 305)微米)。 | |||
T38796L |
MBP MAPK Substrate acetate
MBP MAPK Substrate acetate(138028-00-9 free base) |
MAPK | MAPK |
MBP MAPK Substrate acetate 可用作 MAPK 的外源性底物。 | |||
T20681 |
Estramustine
NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275 |
Microtubule Associated | Cytoskeletal Signaling |
Estramustine (LEO-275) 是一种与雌二醇相连的氮芥,通常为磷酸盐。它已被用于治疗前列腺肿瘤;还具有防辐射功能。它被前列腺细胞选择性吸收,并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。 | |||
T2231 |
Estradiol dipropionate
17-Beta-Estradiol-3,17-Dipropionate,3,17-二丙酸-17-BETA-雌二酯,二丙酸雌二醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Progesterone Receptor | Endocrinology/Hormones; Others |
Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) 是雌激素-孕激素的组合物,可用作雌激素 (estrogen) 孕激素 (progesterone) 激动剂。 | |||
T13674 |
Elacestrant
依拉司群,RAD1901 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Elacestrant (RAD1901) 是一种具有口服活性的、选择性的雌激素受体 (ER) 降解剂 (SERD),能够作用于 ERα (IC50:48 nM)和 ERβ (IC50:870 nM)。 | |||
T11004 |
Desformylflustrabromine hydrochloride
dFBr hydrochloride,Deformylflustrabromine hydrochloride |
AChR | Neuroscience |
Desformylflustrabromine hydrochloride (dFBr hydrochloride) 是α4β2神经元中烟碱乙酰胆碱受体(nAChR)的选择性激动剂,pEC50为6.48。 | |||
T12832 |
Amcenestrant
SAR439859 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Amcenestrant (SAR439859) 是一种有效的 ER 拮抗剂,具有 ER 降解活性,EC50为 0.2 nM。它是一种具有口服活性,非甾体和选择性雌激素受体降解剂 (SERD)。它可在 ER+乳腺癌中表现出强大的抗肿瘤功效和有限的交叉耐药性。 | |||
T2211 |
Dihydrostreptomycin sulfate
Dihydrostreptomycin sesquisulfate,双氢链霉索 |
Antibacterial; Antibiotic | Microbiology/Virology |
Dihydrostreptomycin sulfate (Dihydrostreptomycin sesquisulfate) 是一种氨基糖苷类抗生素,可研究牛、猪和羊的细菌性疾病。 | |||
T9491 |
Pyraclostrobin
|
Antibacterial; Antifungal | Microbiology/Virology |
Pyraclostrobin 是一种球果苷杀菌剂,可诱导 3T3-L1 细胞内甘油三酯的积累,还可抑制真菌和哺乳动物细胞的线粒体复合物 III 。 | |||
T8395 |
Nomegestrol acetate
|
Others; Progesterone Receptor | Others |
Nomegestrol acetate 是一种孕酮受体的完全激动剂,是一种高选择性孕激素。 | |||
T0040 |
Quinestrol
W-3566,Ethinylestradiol 3-cyclopentyl ether,炔雌醇环戊醚,EE2CPE |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Quinestrol (Ethinylestradiol 3-cyclopentyl ether) 是合成的雌激素,用于乳腺癌和前列腺癌的相关研究的潜力。 | |||
T4451 |
Estramustine phosphate sodium
Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠 |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Estramustine phosphate sodium (Ro 21-8837/001) 是雌二醇类似物,是一种具有口服活性抗微管化疗剂,通过与微管相关蛋白和微管蛋白结合而使微管解聚。它可诱导前列腺癌细胞凋亡,可研究前列腺癌。 | |||
T77698 |
hCYP3A4 Fluorogenic substrate 1
|
Others | Others |
hCYP3A4 Fluorogenic substrate 1 是邻苯二甲酰亚胺衍生物,对 COX 表现出低活性。 | |||
TP1485L |
Calcineurin substrate acetate
|
Autophagy | Autophagy |
Calcineurin substrate acetate 来自 cAMP 依赖性蛋白激酶的调节 RII 亚基。 | |||
T4048 |
Monastrol
(±)-Monastrol |
Apoptosis; Kinesin | Apoptosis; Cytoskeletal Signaling |
Monastrol ((±)-Monastrol) 是一种具有高效性和细胞渗透性的有丝分裂驱动蛋白Eg5的抑制剂,IC50值为 14 μM。 | |||
T0168 |
Estradiol (cypionate)
Depofemin,环戊丙酸雌二醇,Estradiol cypionate |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Estradiol cypionate (Depofemin) 是一种 Estradiol 的 17β-环戊丙酸酯,能够作用于雌激素受体。抑制ET-1的合成。 | |||
T61864 |
Melengestrol acetate
|
Progesterone Receptor | Others |
Melengestrol acetate 是孕酮的衍生物,充当皮质类固醇激素。 Melengestrol acetate 可以促进月经活动和妊娠维持的子宫内膜增殖延迟。 | |||
T21275 |
Azoxystrobin
HSDB 7017,ICI-A 5504,Bankit,ICIA-5504,Amistar |
Antifungal | Microbiology/Virology |
Azoxystrobin (Bankit) 是一种广谱杀菌剂。 Azoxystrobin 通过阻断细胞色素 b 和 c1 之间的电子转移来诱导 ROS 产生、细胞凋亡和线粒体呼吸。 | |||
T13260 |
Gastrin/CCK antagonist 1
|
cholecystokinin | GPCR/G Protein |
Gastrin/CCK antagonist 1 是一种有效的 gastrin/CCK 拮抗剂,可用于研究代谢系统相关疾病。 | |||
T26629 |
Angstrom6
A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide |
PAI-1 | Metabolism |
Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽,它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性,能通过与 CD44 结合并调节 CD44 介导的细胞信号传导,抑制肿瘤细胞的迁移、侵袭和转移。 | |||
T15249 |
Estrogen receptor modulator 1
|
Estrogen Receptor/ERR | Endocrinology/Hormones |
Estrogen receptor modulator 1 是一种有效的、具有口服活性的、选择性雌激素受体(estrogen receptor)调节剂 (SERM),其 pIC50为 0.46。它能够诱导 Tamoxifen 耐药、激素非依赖性异种移植瘤的消退。 | |||
TP2030L1 |
Gastrin I (human) acetate
Gastrin I (human) acetate(10047-33-3 free base),Gastrin-17 acetate,Little gastrin I acetate,胃膜素醋酸盐 |
cholecystokinin | GPCR/G Protein |
Gastrin I (human) acetate (Gastrin-17 acetate) 是在胃中产生的内源性肽,通过胆囊收缩素 2 (CCK2) 受体增加胃酸分泌。 | |||
T2597 |
Norgestrel
甲基炔诺酮,SH-850,FH 122-A,炔诺孕酮,WY-3707,SH-70850 |
Estrogen/progestogen Receptor; Reactive Oxygen Species | Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB |
Norgestrel (WY-3707) 是一种孕酮的合成类似物,是一种口服避孕药中常见的化合物,也是一种神经保护性强抗氧化剂,能够防止光诱导的感光细胞中的ROS 的生成以及细胞死亡。 | |||
T5118 |
Brilanestrant
GDC0810,GDC 0810,GDC-0810,ARN-810,RG 6046 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Brilanestrant (GDC-0810) 是一种雌激素选择性降能器 (selective estrogen receptor degrader)(IC50:0.7 nM),口服具有活性。 | |||
T2567 |
Etonogestrel
3-Oxodesogestrel,3-keto-Desogestrel,依托孕烯,Nexplanon,Implanon |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism; Others |
Etonogestrel (Implanon) 是孕激素去氧孕烯的生物活性代谢物,与靶器官中的孕酮受体和雌激素受体高亲和力地结合,可诱导FKBP51mRNA 和蛋白表达。它是一种甾体孕激素,用作激素避孕药。 | |||
T1536 |
Promestriene
3-propyl ethyl,舒经劳,17B-methyl estradiol,Promestriano |
Estrogen/progestogen Receptor | Endocrinology/Hormones |
Promestriene (3-propyl ethyl) 是局部有效的雌激素,是合成的雌二醇二乙醚。它对阴道萎缩有作用,但吸收量小。 | |||
T37207L |
Cdk5 Substrate acetate
|
CDK | Cell Cycle/Checkpoint |
Cdk5 Substrate acetate 是一种丝氨酸/苏氨酸激酶,主要在神经元组织中具有活性。与 p25 或 p35 一起,Cdk5 磷酸化一系列蛋白质,包括组蛋白 H1 和 tau。 它是一种合成肽 (PKTPKKAKKL),对应于组蛋白 H1 的序列。它被 Cdk5 磷酸化,Km 值为 5 µM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1263 |
Levonorgestrel
左炔诺孕酮,D-Norgestrel |
Others; Estrogen/progestogen Receptor; Progesterone Receptor | Endocrinology/Hormones; Others |
Levonorgestrel (D-Norgestrel) 是一种合成孕激素,可作用于孕酮受体。它是一种宫内节育器,可以抑制卵子受精。 | |||
T2953 |
Ligustrazine hydrochloride
Tetramethylpyrazine hydrochloride,Tetramethylpyrazine HCl,Chuanxiongzine hydrochloride,Tetrapyrazine HCl,盐酸川芎嗪 |
Others | Others |
Ligustrazine hydrochloride (Chuanxiongzine hydrochloride) 是一种天然产物。 | |||
T5575 |
Cycloastragenol
环黄芪醇,Cyclogalegenol,Astramembrangenin |
Epigenetic Reader Domain; Telomerase | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Cycloastragenol (Astramembrangenin) 是一种三萜皂苷类化合物,是黄芪主要活性成分的水解产物,具有抗氧化、抗炎、抗衰老、抗凋亡和心血管保护作用。它是端粒酶激活剂,可以延长端粒,还能缓解与年龄相关的骨丢失,改善骨微结构和生物力学特性。 | |||
T2973 |
Astragaloside IV
AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV |
MMP; ERK; Estrogen/progestogen Receptor; JNK | Endocrinology/Hormones; MAPK; Proteases/Proteasome |
Astragaloside IV (AS-IV) 是从黄芪中分离得到的一种皂苷,抑制ERK1/2和JNK 激活,在乳腺癌细胞 MDA-MB-231 中,下调(MMP)-2和(MMP)-9的信号通路。 | |||
T3925 |
Astragaloside I
黄芪皂苷I,Cyclosieversioside B,Astrasieversianin IV |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
Astragaloside I (Cyclosieversioside B) 是从黄芪中分离得到天然产物。它可通过 Wnt/β-catenin 信号通路刺激成骨细胞分化,可用于成骨活性研究。 | |||
T5S0836 |
Isoastragaloside II
黄芪甲苷VII,Astrasieversianin VII |
Others | Others |
Isoastragaloside II (Astrasieversianin VII) 是一种是从黄芪毛状根培养分离得到的黄芪甲苷。 | |||
T3605 |
Gastrodenol
Bismuth tripotassium dicitrate,枸橼酸铋钾,Bismuth subcitrate |
Others | Others |
Gastrodenol (Bismuth tripotassium dicitrate) 是一种对溃疡和胃不适具有潜在的应用价值的药物。 | |||
TN2083 |
Pinostrobin chalcone
球松素查尔酮,2',3'-二羟基-4'-甲氧基查耳酮 |
||
Pinostrobin chalcone 是一种从豆科植物木豆中分离出的查尔酮类化合物,具有抗癌活性,对 MDA-MB-231 的 IC50 值为 20.42±2.23μg/mL,对 HT-29 结肠癌细胞株的IC50 值为 22.51±0.42 μg/mL。 | |||
T1679 |
Thiostrepton
Thiactin,Bryamycin,Alaninamide,硫链丝菌素 |
DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Thiostrepton (Alaninamide) 是一种选择性抑制FOXM1的抗生素。FOXM1会与 YAP/TEAD 复合物结合,形成YAP/TEAD/FOXM1 复合物。 | |||
T2220 |
2-Methoxyestradiol
2-甲氧雌二醇,二甲氧基雌二醇,NSC-659853,2-MeOE2,2-ME2 |
Apoptosis; Reactive Oxygen Species; Microtubule Associated; Endogenous Metabolite; HIF; Autophagy | Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB |
2-Methoxyestradiol (2-ME2) 是一种口服生物可利用的雌二醇代谢物,具有抗肿瘤活性。它通过减少内皮细胞增殖和诱导内皮细胞凋亡来抑制血管生成,也可破坏微管的稳定。它可诱导半胱天冬酶活化,导致细胞周期停滞在 G2 期、DNA 断裂和细胞凋亡。 | |||
T2722 |
Ligustrazine
川芎嗪,四甲基吡嗪,Tetramethylpyrazine |
Apoptosis; Antioxidant | Apoptosis; oxidation-reduction |
Ligustrazine (Tetramethylpyrazine) 是从Ligusticum wallichii 中提取的一种烷基吡嗪,常在薯条、面包、茶、乳制品、豆制品等食物中作为香精。它对大鼠具有潜在的抗神经和抗炎活性。 | |||
TN1773 |
Isoastragaloside IV
异黄芪皂苷 IV,异黄芪皂苷IV |
Others | Others |
Isoastragaloside IV 是一种天然三萜糖苷类产物,来源于黄芪中。 | |||
T1507 |
Streptozocin
STZ,Streptozotocin,链脲佐菌素,NSC-85998,链脲菌素,U 9889 |
DNA Alkylator/Crosslinker; DNA Alkylation; DNA/RNA Synthesis; Antibacterial; Antibiotic; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Streptozocin (NSC-85998) 是一种抗生素,可诱导 DNA 甲基化。Streptozocin 对产生胰岛素的胰岛 B 细胞具有毒性,常用于构建 1 型糖尿病的动物模型。该产品在溶液中不稳定,建议现配现用。 | |||
T8178 |
Acetagastrodin
乙酰天麻素,Acegastrodine |
Others | Others |
Acetagastrodin (Acegastrodine) 是一种抗氧化剂,也是合成 DBPG 的中间体。 | |||
T1424 |
Ethynyl estradiol
乙炔基雌二醇,17α-Ethynylestradiol,Ethinyl Estradiol,炔雌醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Ethynyl estradio 是一种高效的生物活性雌激素。 | |||
T1571 |
Estriol
NSC-12169,Oestriol,雌三醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite | Endocrinology/Hormones; Immunology/Inflammation; Metabolism |
Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。 | |||
T1048 |
Estradiol
雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Estradiol (E2) 是一种天然的类固醇性激素,对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。 | |||
T1009 |
Estrone
Oestrone,雌酮,Fluoroethyl,Aquacrine |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Estrone (Aquacrine) 是内源性雌激素的主要代表,由多种组织产生,尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。 | |||
T16338 |
Norgestimate metabolite Norelgestromin
17-Deacetyl norgestimate,17-Deacylnorgestimate,甲基孕酮 |
Drug Metabolite | Metabolism |
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) 是norgestimate 的一种活性代谢物。它是用于避孕贴片的甾体孕激素,与雌激素乙炔雌二醇结合使用。 | |||
T7299 |
β-Estradiol 17-acetate
β-雌二醇 17-乙酸酯,17-乙酸-17-BETA-雌二酯,beta-estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate |
Estrogen Receptor/ERR; Others | Endocrinology/Hormones; Others |
β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) 是一种雌二醇代谢物。 | |||
T7974 |
Lynestrenol
|
Progesterone Receptor | Others |
Lynestrenol 是孕烷 X 受体 (PXR) 激动剂,能够作用于 hPXR(EC50:41 µM) 和 zfPXR(EC50:0.23 µM)。它是合成的孕酮,具有免疫刺激作用。 | |||
TQ0171 |
Isoastragaloside I
|
Others | Others |
Isoastragaloside I 是一种中药黄芪的天然化合物,能够增强脂联素量活性。 | |||
TN5073 |
Strophanthidin
毒毛旋花子甙元,Strophanthidine,葡萄球菌素 |
ATPase; Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Strophanthidin (Strophanthidine) 是黄花夹竹桃中的一种类固醇,可增加舒张期和收缩期胞内 Ca2+浓度。它在 0.1 和 1 nmol/L 增加Na+/K+-ATPase 活性,1到100 μ mol/L 抑制Na+/K+-ATPase 活性,10 和 100 nmol/L 对Na+/K+-ATPase 活性无影响。 | |||
T5649 |
Estragole
4-烯丙基苯甲醚,Methyl chavicol,p-Allylanisole,4-Allylanisole,草蒿脑 |
Others | Others |
Estragole (4-Allylanisole) 是一种相对无毒的挥发性萜类醚,是许多植物精油的主要成分。它具有抗弓形虫作用。它剂量依赖性地阻断神经兴奋。 | |||
T3802 |
Ligustroflavone
女贞苷,Nuezhenoside |
Others; CaSR | GPCR/G Protein; Others |
Ligustroflavone (Nuezhenoside) 是一种潜在的钙敏感受体拮抗剂,提取自 Ligustrum lucidum,对糖尿病性骨质疏松症小鼠有保护作用。 | |||
T6395 |
Astragaloside A
Astragalin A,黄芪甲苷,Astramembrannin I |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Astragaloside A (Astramembrannin I) 是从黄芪中分离得到的初级纯皂苷,已广泛用于心血管疾病的治疗。 | |||
T3378 |
Alpha-Estradiol
α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol |
Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Alpha-Estradiol (Epiestradiol) 是一种雌性激素,可抑制5α-reductase,在雄原性脱发的研究中有潜力。 | |||
T0060 |
Streptomycin sulfate
Plantomycin,Estreptomicina,Phytomycin,硫酸链霉素 |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Streptomycin sulfate (Phytomycin) 是一种能抑制蛋白质合成的氨基糖苷类抗生素。 | |||
TN2239 |
Strictosamide
异长春花苷内酰胺 |
ATPase; Potassium Channel; Sodium Channel; Parasite; Antifungal | Membrane transporter/Ion channel; Microbiology/Virology |
Strictosamide 具有抗炎、抗疟原虫和抗真菌活性。 | |||
T1284 |
Megestrol acetate
SC10363,醋酸甲地孕酮,BDH1298 |
Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; HIV Protease; Autophagy | Autophagy; Endocrinology/Hormones; Microbiology/Virology; Others; Proteases/Proteasome |
Megestrol acetate (BDH1298) 是具有口服活性的合成孕激素。它还具有抗雄激素特性,可用于治疗厌食症和恶病质。 | |||
T2S0886 |
Terrestrosin D
|
Apoptosis; Others | Apoptosis; Others |
Terrestrosin D 是从刺蒺藜中提取得到一种的甾体皂苷,可诱导细胞周期阻滞和癌细胞凋亡,具有抗血管生成的活性。 | |||
T6S1101 |
Astragalin
Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,紫云英苷,Kaempferol 3-β-D-glucopyranoside |
Apoptosis; NF-κB | Apoptosis; NF-κB |
Astragalin (Kaempferol 3-O-glucoside) 是一种具有生物活性的天然黄酮类化合物。 它具有多种药理特性,包括抗氧化、抗炎、抗癌、神经保护和心脏保护特性。 | |||
T36857 |
Estrone sulfate sodium
雌酮3-硫酸钠,Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate |
Endogenous Metabolite | Metabolism |
Estrone sulfate sodium (17β-Estrone 3-sulfate) 是一种主要的循环血浆雌激素,无生物活性,通过类固醇硫酸酯酶(STS) 转化为生物活性雌激素雌酮。 | |||
T5S0833 |
Astragaloside III
|
Antioxidant | oxidation-reduction |
Astragaloside III 是一种分离自黄芪中的一种天然产物。 | |||
T3924 |
Astragaloside II
黄芪皂苷 II,Astrasieversianin VIII |
TGF-beta/Smad | Stem Cells |
Astragaloside II (Astrasieversianin VIII) 是一种分离自黄芪中的天然化合物。 | |||
T4082 |
Astragaloside
|
MMP; ERK; JNK | MAPK; Proteases/Proteasome |
Astragaloside 是黄芪中的主要活性成分之一。 | |||
TQ0295 |
Coumestrol
拟雌内酯,考迈斯托醇 |
Estrogen Receptor/ERR | Endocrinology/Hormones |
Coumestrol 是一种大豆产品中存在的植物雌激素。它抑制ES2细胞增殖的IC50值为50 μM。它可用于癌症,神经障碍和自身免疫疾病的研究。 | |||
T0345 |
Estropipate
雌酮硫酸酯哌嗪,Piperazine estrone sulfate,Pipestrone,Estrone sulfate piperazine salt |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Estropipate (Piperazine estrone sulfate) 是一种由硫酸雌酮和哌嗪组成的天然雌激素物质。 | |||
T2999 |
Gastrodin
天麻素,Gastrodine |
Others | Others |
Gastrodin (Gastrodine) 是中草药天麻的主要成分,具有抗炎活性,常用于研究头晕,癫痫,中风和痴呆症。 | |||
T73772 |
Estrone sulfate potassium
|
Endogenous Metabolite | Metabolism |
Estrone sulfate potassium 是一种雌激素酯和共轭物,是一种天然内源性类固醇。 | |||
TN7020 |
Astragenol
|
Others | Others |
Astragenol 是合成黄芪醇衍生物的中间体。它的衍生物具有抗炎作用,可用于前列腺癌的研究。 | |||
T2S0837 |
Astragalus Polysacharin
2-(Chloromethyl)-4-(4-nitrophenyl)thiazole,黄芪多糖,89250-26-0 |
TAM Receptor | Tyrosine Kinase/Adaptors |
2-(Chloromethyl)-4-(4-nitrophenyl)thiazole 是一种从黄芪 (Astragalus propinquus) 中提取得到的天然产物。2-(Chloromethyl)-4-(4-nitrophenyl)thiazole 具有抗癌活性,通过抑制肿瘤相关巨噬细胞 (TAM) 的 M2 极化在肝细胞癌 (HCC) 中显示除抗肿瘤活性。 | |||
TN2082 |
Pinostrobin
|
Beta Amyloid; IL Receptor; Serine/threonin kinase; TNF | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience |
Pinostrobin 是一种 PCSK9抑制剂,可抑制 PCSK9 的催化活性。它是能够在多种植物中发现的黄酮类化合物,并具有抗氧化,抗炎,抗癌和神经保护作用。它是有前景的胆固醇调节和脂质管理剂。 | |||
T13481 |
2-Methoxyestrone
|
Endogenous Metabolite | Metabolism |
2-Methoxyestrone 是甲氧基苯二酚雌激素,也是雌酮代谢物,其 pKa=10.81。 | |||
T9454 |
4-Hydroxyestrone
|
Estrogen Receptor/ERR; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
4-Hydroxyestrone 是一种内源性雌激素代谢物,可强烈保护神经元细胞免受氧化损伤。 | |||
T9455 |
4-hydroxyestrone-4-methyl ether
4-Methoxy Estrone,4-甲氧基雌酮 |
Estrogen Receptor/ERR; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
4-hydroxyestrone-4-methyl ether (4-Methoxy Estrone) 是由COMT 催化的4-OHE1的甲基化反应。 | |||
TN6109 |
5-Carboxystrictosidine
(5S)-5-Carboxystrictosidine |
||
5-Carboxystrictosidine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6109,CAS号为 34371-47-6。 | |||
T9456 |
4-Methoxy 17β-Estradiol
|
Others | Others |
4-Methoxy 17β-Estradiol 是雌激素代谢物之一,也是 4-羟基雌二醇的甲基化代谢物。 | |||
TN3481 |
12-Deoxywithastramonolide
Baimantuoluoside C |
Others | Others |
12-Deoxywithastramonolide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3481,CAS号为 60124-17-6。 | |||
TN1412 |
Astringin
trans-Astringin,白皮杉醇葡萄糖苷 |
IL Receptor; Others | Immunology/Inflammation; Others |
Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin in the ischemic and ischemic-reperfused hearts may be correlated with its antioxidant activity and upregulation of NO production. | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03971 |
Statherin Protein, Human, Recombinant (mFc)
statherin,STATH,STR |
Human | HEK293 Cells |
Statherin, also known as STATH, belongs to the histatin/statherin family. Statherin may play an important role in the maintenance of oral health. It prevents calcium phospate precipitation in saliva, so maintaining a high calcium level in saliva and preventing teeth from dissolving. Statherin also inhibits spontaneous precipitation of calcium phosphate salts. Thus, statherin and PRPs may prevent build-up of harmful deposits in the salivary glands and on the tooth surfaces. Statherin is a highly ... | |||
TMPH-03402 |
STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc)
|
Rauvolfia serpentina | E. coli |
Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is P68175. | |||
TMPY-02689 |
MMP-3 Protein, Human, Recombinant
STMY,MMP-3,matrix metallopeptidase 3,CHDS6,STMY1,SL-1,ST... |
Human | E. coli |
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This prot... | |||
TMPY-00065 |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His)
Matrix protein VP40 |
EBOV | E. coli |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.4 kDa and the accession number is B8XCM9. | |||
TMPY-06572 |
Vaccinia virus (VACV) (strain Copenhagen) Protein B5 (His)
|
VACV | HEK293 Cells |
Vaccinia virus (VACV) (strain Copenhagen) Protein B5 (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.53 kDa and the accession number is P21115. | |||
TMPY-04689 |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His)
E Protein, DENV |
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is AAC59274.1. | |||
TMPY-05346 |
CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)
SpyCas9 |
Streptococcus pyogenes | Baculovirus Insect Cells |
CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 163 kDa and the accession number is Q99ZW2. | |||
TMPY-04870 |
Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 protein (His)
|
ZIKV | HEK293 Cells |
Zika virus NS1 antigen is one of seven non-structural proteins. NS1 is involved in RNA replication. The possible effects of NS1 on hosts include: localizes to host cell surface and secreted extracellularly, modulates signalling of the innate immune system, has possible damages to platelets and endothelial cells through anti-NS1 antibodies. | |||
TMPY-02219 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
NS1 Protein |
H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As... | |||
TMPY-03236 |
Human respiratory syncytial virus (RSV) Fusion protein/RSV-F (Strain RSS-2) Protein (His)
F Protein,HRSVgp8 |
RSV | Baculovirus Insect Cells |
Human respiratory syncytial virus (RSV) Fusion protein/RSV-F (Strain RSS-2) Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.8 kDa and the accession number is P11209. | |||
TMPY-04903 |
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 Protein (His)
DENV-NS1 |
DENV | HEK293 Cells |
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is AAA99437.1. | |||
TMPY-04892 |
Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (His)
|
ZIKV | Baculovirus Insect Cells |
Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 45.5 kDa and the accession number is ALU33341.1. | |||
TMPY-00052 |
Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (His)
DENV-NS1 |
DENV | HEK293 Cells |
Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is AAC59275.1. | |||
TMPY-04865 |
Chikungunya virus (CHIKV) (strain SL-CK1) E2/Envelope 2 Protein (His)
|
CHIKV | Baculovirus Insect Cells |
Chikungunya virus (CHIKV) (strain SL-CK1) E2/Envelope 2 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.8 kDa and the accession number is A5Y7Y5. | |||
TMPY-04192 |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591. | |||
TMPY-05824 |
Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 247-675, His)
E Protein |
DENV | HEK293 Cells |
Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 247-675, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.79 kDa and the accession number is AAA99437.1. | |||
TMPY-01552 |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is B6DRA0. | |||
TMPY-02285 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein
NS2 Protein |
H1N1 | E. coli |
Non-structural protein 2 (NS2) plays a crucial role in the hepatitis C virus (HCV) assembly. NS2 was predicted to be composed of three transmembrane (TM) segments. Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a hydrophobic, transmembrane protein that is required not only for NS2-NS3 cleavage but also for infectious virus production.NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and ant... | |||
TMPH-00258 |
Bovine coronavirus (strain Quebec) Spike glycoprotein (His)
S,E2,Spike glycoprotein,S glycoprotein,Peplomer protein |
BCoV | P. pastoris (Yeast) |
Bovine coronavirus (strain Quebec) Spike glycoprotein (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 36.8 kDa and the accession number is P25193. | |||
TMPH-00255 |
Bovine coronavirus (strain LSU-94LSS-051) Protein I (His)
N internal ORF protein,Accessory protein N2,IORF,N,I,Protein... |
BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain LSU-94LSS-051) Protein I (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q9QAR0. | |||
TMPH-00253 |
Bovine coronavirus (strain 98TXSF-110-LUN) Protein I (His)
IORF,N,Protein in nucleocapsid ORF,N internal ORF protein,Ac... |
BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain 98TXSF-110-LUN) Protein I (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q8V431. | |||
TMPH-00252 |
Bovine coronavirus (strain Mebus) Protein I (His)
IORF,Protein in nucleocapsid ORF,N,I,Accessory protein N2,N ... |
BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain Mebus) Protein I (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 25.5 kDa and the accession number is P10525. | |||
TMPH-00240 |
Bovine coronavirus (strain LY-138) Non-structural Protein 2a (E. coli, His)
32 kDa accessory protein,Non-structural protein 2a,... |
BCoV | E. coli |
Bovine coronavirus (strain LY-138) Non-structural Protein 2a (E. coli, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is Q9QAS3. | |||
TMPH-00234 |
Bovine coronavirus (strain LSU-94LSS-051) Non-structural Protein 2a (E. coli, His)
2a,32 kDa accessory protein,Non-structural protein ... |
BCoV | E. coli |
Bovine coronavirus (strain LSU-94LSS-051) Non-structural Protein 2a (E. coli, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 33.1 kDa and the accession number is P0C2R3. | |||
TMPH-00244 |
Bovine coronavirus (strain OK-0514) Non-structural Protein 4b (His & SUMO)
4.8 kDa accessory protein,ns4.8,Non-structural prot... |
BCoV | E. coli |
Bovine coronavirus (strain OK-0514) Non-structural Protein 4b (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 17.9 kDa and the accession number is P0C2R8. | |||
TMPH-00412 |
BoNT/D Protein, Clostridium botulinum, Recombinant (B2M & His)
Bontoxilysin-D,Botulinum neurotoxin type D,BoNT/D,botD |
Clostridium botulinum | E. coli |
BoNT/D Protein, Clostridium botulinum, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 64.5 kDa and the accession number is P19321. | |||
TMPY-06023 |
IdeS Protein, Streptococcus pyogenes, Recombinant (His)
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Streptococcus pyogenes | E. coli |
IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus. IdeS Protein, Streptococcus pyogenes, Recombinant (His) is expressed in E. coli expression system with His t... | |||
TMPH-03734 |
Zaire ebolavirus (strain Mayinga-76) L Protein (His)
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ZEBOV | E. coli |
Zaire ebolavirus (strain Mayinga-76) L Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.9 kDa and the accession number is Q05318. | |||
TMPH-03079 |
Sialidase Protein, Paeniclostridium sordellii, Recombinant (His & Myc)
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Paeniclostridium sordellii | E. coli |
Sialidases have been suggested to be pathogenic factors in microbial infections. Sialidase Protein, Paeniclostridium sordellii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.2 kDa and the accession number is P15698. | |||
TMPY-00054 |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc)
Macaca fascicularis Cytωlovirus (CyCMV) (strain OT-... |
CyCMV | HEK293 Cells |
Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 102.5 kDa and the accession number is E7DB34. | |||
TMPH-03695 |
VSIV (strain 98COE North America) Matrix Protein (His & Myc)
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VSIV | E. coli |
VSIV (strain 98COE North America) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.5 kDa and the accession number is Q8B0I2. | |||
TMPY-06491 |
Influenza B (B/Austria/1359417/2021) Nucleoprotein/NP Protein (His)
Nucleoprotein,NP Protein |
Influenza B | Baculovirus Insect Cells |
Influenza B (B/Austria/1359417/2021) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 63 kDa. | |||
TMPH-00406 |
ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)
Butyrate--acetoacetate CoA-transferase subunit B,ctfB,Coat B... |
Clostridium acetobutylicum | E. coli |
Involved in solventogenic switch which allows C.acetobutylicum to uptake acid and produce solvents. Acts mainly to detoxify the medium by removing the acetate and butyrate excreted earlier in the fermentation. ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.6 kDa and the accession number is P23673. | |||
TMPH-03416 |
Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO)
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RVFV | E. coli |
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles. Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.... | |||
TMPH-00429 |
Con-ikot-ikot Protein, Conus striatus, Recombinant (His)
Con-ikot-ikot,CII |
Conus striatus | E. coli |
Con-ikot-ikot Protein, Conus striatus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is P0CB20. | |||
TMPH-03404 |
Reovirus type 3 (strain Dearing) Outer capsid protein sigma-3 (His)
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Reo-3 | E. coli |
Stimulates translation by blocking the activation of the dsRNA-dependent protein kinase EIF2AK2/PKR, thereby inhibiting the host interferon response. Sigma3 prevents the activation of EIF2AK2 by competing with the kinase for dsRNA-binding.; The viral outer shell polypeptides, of which sigma-3 is one, impose structural constraints that prevent elongation of nascent transcripts by the RNA-dependent RNA polymerase lambda-3. Reovirus type 3 (strain Dearing) Outer capsid protein sigma-3 (His) is expr... | |||
TMPH-00145 |
IBV (strain H52) Nucleoprotein/NP Protein (His)
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IBV | HEK293 Cells |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. IBV (strain H52) Nucleoprotein/NP Protein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 47.4 kDa and the accession number ... | |||
TMPH-00131 |
Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc)
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Aspergillus restrictus | E. coli |
This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.9 kDa and the accession number is P67876. | |||
TMPH-00540 |
Epstein-Barr virus (strain GD1) LMP1 Protein (His)
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EBV | P. pastoris (Yeast) |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... | |||
TMPH-00547 |
Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc)
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EBV | E. coli |
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. | |||
TMPH-03690 |
VEEV (strain 3880) P1234 Protein (His)
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VEEV | E. coli |
VEEV (strain 3880) P1234 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 55.7 kDa and the accession number is P36327. | |||
TMPH-03598 |
Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)
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Streptococcus pyogenes | E. coli |
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) is expressed in E. coli expression system with... | |||
TMPH-03667 |
Vaccinia virus (strain Copenhagen) OPG190 Protein (His)
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VACV | P. pastoris (Yeast) |
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracellular enveloped virions (IEV). Vaccinia virus (strain Copenhagen) OPG190 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is P21115. | |||
TMPH-02412 |
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc)
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LCMV | E. coli |
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.9 kDa and the accession number is P07399. | |||
TMPY-01558 |
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)
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HIV | HEK293 Cells |
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.4 kDa. | |||
TMPH-03732 |
Zaire ebolavirus (strain Kikwit-95) VP35 Protein (E. col, His & Myc)
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ZEBOV | E. coli |
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes. Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1. VP35-NP interaction controls the switch between RNA-bound NP and free NP and thus the switch between gen... | |||
TMPK-00696 |
PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)
MAPKAPK5,MK5,MAPKAP-K5,MK-5,MAPKAPK-5 |
Human | Baculovirus Insect Cells |
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway. | |||
TMPH-01452 |
Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc)
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HHV-6A | E. coli |
Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc) is expressed in E. coli. | |||
TMPY-04895 |
Zika virus (strain Zika SPH2015) E/Envelope protein (His)
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ZIKV | P. pastoris (Yeast) |
Zika virus (strain Zika SPH2015) E/Envelope protein (His) is expressed in yeast with His tag. The predicted molecular weight is 12.9 kDa and the accession number is ALU33341.1. | |||
TMPY-04196 |
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P18800. | |||
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