153
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1
288
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0098 |
HER2 inhibitor kit
HER2 inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76787 |
Conatumumab
TRAIL-R2 mAb,AMG 655 |
TNF | Apoptosis |
Conatumumab (AMG 655) 是一种靶向人死亡受体 5 (DR5,TRAILR2) 的单克隆激动剂抗体 ,对长型 DR5 的 Kd 为 1 nM, 对短型 DR5 的 Kd 0.8 nM。Conatumumab 通过半胱天冬酶激活在多种肿瘤类型中诱导细胞凋亡。Conatumumab 可用于研究晚期实体肿瘤。 | |||
T24700 |
R243
R 243,R-243 |
CCR | Immunology/Inflammation; Microbiology/Virology |
R243 是选择性的CCR8拮抗剂,可抑制CCL1/CCR8的相互作用,以及CCR8信号传导和趋化性,具有抗伤害感受和抗炎作用。 | |||
T62204 |
NR2F6 modulator-1
|
Others | Others |
NR2F6 modulator-1 是一种核受体亚族 2,F 组第 6 号成员 (NR2F6) 的有效调节剂。NR2F6 modulator-1 能够用于研究免疫调节和肿瘤干细胞活性的调节。 | |||
T27682 |
CCR2 antagonist 5
JNJ-41443532,JNJ-41443532 Free Base,JNJ 41443532,JNJ41443532 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2 antagonist 5 (JNJ-41443532) 是一种具有选择性和口服活性的 hCCR2 抑制剂,具有良好的结合亲和力 (IC50=37 nM) 和有效的功能拮抗作用 (chemotaxis IC50=30 nM)。JNJ-41443532 对 mCCR2 结合的 Ki 为 9.6 µM, 可用于研究炎症性疾病和糖尿病。 | |||
T60000 |
STING (WT/R232) activity regulator 126
|
STING | Immunology/Inflammation |
STING (WT/R232) activity regulator 126 是一种具有抗菌和抗病毒作用的 STING 调节剂。 | |||
T11279 |
FGFR1/DDR2 inhibitor 1
|
Discoidin Domain Receptor (DDR); FGFR; Others | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
FGFR1/DDR2 inhibitor 1 是一种具有口服活性的成纤维细胞生长因子受体 1 和盘状蛋白域受体 2 的抑制剂,能够抑制 FGFR1 (IC50:31.1 nM) 和 DDR2 (IC50:3.2 nM),具有抗肿瘤作用。 | |||
T77523 |
ALR2-IN-1
|
Reductase | Endocrinology/Hormones; Metabolism |
ALR2-IN-1 是一种有效的且具有选择性的 ALR2 抑制剂 ,IC50值为1.42 μM。ALR2-IN-1 具有抗糖和抗氧化活性, 可用于研究糖尿病并发症。 | |||
T14688 |
BMS CCR2 22
|
CCR | Immunology/Inflammation; Microbiology/Virology |
BMS CCR2 22 是一种有效的选择性 CC 型趋化因子受体2拮抗剂,钙通量 IC50为 18 nM,趋化性 IC50为1 nM,结合 IC50为5.1 nM。 | |||
T13114 |
CCR2 antagonist 4
Teijin compound 1 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2 antagonist 4 (Teijin compound 1) 是高效的、特异性的CCR2拮抗剂,对 CCR2b 的IC50为 180 nM,抑制 MCP-1 诱导的趋化作用的 IC50为 24 nM。 | |||
T8763 |
PTGR2-IN-1
PTGR2-IN-22 |
Others | Others |
PTGR2-IN-1 是有效的 PTGR2抑制剂,IC50为 ~0.7 μM。它能够提高转染 PTGR2 的 HEK293T 细胞 15-keto-PGE2 依赖的 PPARγ 转录活性。 | |||
T14900 |
CCR2-RA-[R]
(5R)-4-乙酰基-1-(4-氯-2-氟苯基)-5-环己基-1,5-二氢-3-羟基-2H-吡咯-2-酮 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2-RA-[R] 是一种 C-C 趋化因子受体 2 型 (CCR2) 变构拮抗剂,IC50值为103 nM。 | |||
T9724 |
VEGFR2-IN-2
|
Others | Others |
VEGFR2-IN-2 具有抗炎和镇痛活性。 | |||
T61304 |
FGFR2-IN-1
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR2-IN-1是一种 FGFR 抑制剂,对 FGFR1、FGFR2和FGFR3具有抑制作用, IC50 分别为460、140和2200 nM。FGFR2-IN-1 可用于研究与 FGFR2 相关的癌症。 | |||
T61899 |
VEGFR2-IN-1
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
VEGFR2-IN-1 是一种具有选择性和高效性的 VEGFR2 抑制剂,具有抗肿瘤活性,可抑制细胞的增殖和迁移,可用于研究乳腺癌。 | |||
T3155 |
SMER28
|
Autophagy | Autophagy |
SMER28 是一种自噬小分子增强剂,通过不依赖于 mTOR 的机制诱导哺乳动物细胞中独立于雷帕霉素的自噬,并阻止淀粉样蛋白 β 肽的积累。 | |||
T7016 |
VR23
|
Apoptosis; Proteasome; Caspase | Apoptosis; Proteases/Proteasome; Ubiquitination |
VR23 是一种蛋白酶体抑制剂,对胰蛋白酶样蛋白酶体、糜蛋白酶样蛋白酶体和半胱天冬酶样蛋白酶体的 IC50 分别是1 nM、50-100 nM 和3 μM。 | |||
T22749 |
DR2313
DR 2313 |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
DR2313 是一种选择性,竞争性的和可透过血脑屏障的PARP 抑制剂,对PARP-1和PARP-2的IC50值分别为 0.20 和 0.24 μM。它在体内外均有对缺血性损伤的神经保护作用。 | |||
T11600 |
IBR2
Isoquinoline |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
IBR2(Isoquinoline)是一种针对RAD51的强效特异性抑制剂,通过干预RAD51多聚体形成,加速蛋白酶体介导的RAD51蛋白降解,抑制癌细胞生长并诱导凋亡。实验证明在抑制RAD51介导的DNA双链断裂修复方面有效。 | |||
T10712 |
CCR2 antagonist 3
AZD-2927,AZD2927 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2 antagonist 3 (AZD-2927) 是 CCR2的拮抗剂。 | |||
T5048 |
SSR240612
|
Bradykinin Receptor | GPCR/G Protein |
SSR240612 是口服有活性的非肽类缓激肽 B1 (bradykinin B1) 受体特异性拮抗剂。 | |||
T13112L1 |
Tat-NR2B9c acetate
Tat-NR2B9c acetate (500992-11-0 Free base),NA-1 acetate |
Others | Others |
Tat-NR2B9c acetate (NA-1 acetate) 是一种突触后密度 95 (PSD-95) 抑制剂,对 PSD-95d2 (PSD-95 PDZ domain 2) 和 PSD-95d1 的 EC50 值分别为 6.7 nM 和 670 nM。它破坏 PSD-95/NMDAR 相互作用,抑制 NR2A 和 NR2B 与 PSD-95 的结合,IC50 值分别为 0.5 μM 和 8 μM。它还抑制神经元一氧化氮合酶 (nNOS)/PSD-95 相互作用,并具有神经保护功效。 | |||
T22282 |
Brr2-IN-3
Brr2 Inhibitor 9,Brr2 Inhibitor C9 |
Others | Others |
Brr2-IN-3 (Brr2 Inhibitor C9) 是选择性 Brr2解旋酶变构抑制剂。它呈剂量依赖性地抑制解旋酶(IC50:1.3 μM)。 | |||
T60185 |
FGFR2-IN-3
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR2-IN-3 是一种具有口服活性的选择性 FGFR2抑制剂。 | |||
T13112 |
Tat-NR2B9c
Tat-NR2Bct,NA-1 |
NO Synthase; iGluR | Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience |
Tat-NR2B9c (NA-1) 是一种突触后密度-95(PSD-95)抑制剂,具有神经保护和抗癫痫作用。Tat-NR2B9c 可抑制PSD-95d2、 PSD-95d1 和 PSD-95,可阻止NMDA诱导的神经元NADPH氧化酶的激活,从而阻断超氧化物的产生,可减少中风后急性期的缺血性损伤。 | |||
T22752L |
(D-Ser2)-Leu-Enkephalin-Thr
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
(D-Ser2)-Leu-Enkephalin-Thr 是阿片受体的 delta 选择性药物,具有镇痛作用。 | |||
T10905 |
CXCR2-IN-1
|
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
CXCR2-IN-1是可渗透中枢神经系统的 CXCR2拮抗剂,pIC50值为9.3。 | |||
T16929 |
SR2211
|
ROR | Metabolism |
SR2211 是一种特异性调节剂和 RORγ 的反向激动剂(IC50 = 320 nM,Ki = 105 nM)。 | |||
T26332 |
WR23
WR 23,WR-23 |
||
WR23 is a piperidinylquinoxaline derivative and a phosphoinositide 3-kinase α (PI3Kα) inhibitor. | |||
T64253 | EGFR/HER2-IN-4 | ||
EGFR/HER2-IN-4 是一种不可逆的、口服具有活力的双重抑制剂,能够抑制 EGFR 的活性 (IC50: 0.6 nM)。EGFR/HER2-IN-4 对 L858R 和 T790M 突变显示出有效的 EGFR 激酶抑制活性。EGFR/HER2-IN-4 在体内表现出明显的抗肿瘤作用,能够用于研究肺癌。 | |||
T60896 | HER2-IN-11 | ||
HER2-IN-11 是能够诱导细胞凋亡的补骨脂素衍生物。HER2-IN-11 显示出光激活细胞毒性,并且具有抗乳腺癌活性。 | |||
T39983 | SPR206 acetate | ||
SPR206 acetate is a polymyxin analog that exhibits antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. By interacting with the outer membrane of the bacterium, SPR206 acetate effectively combats bacterial infections. Notably, SPR206 acetate demonstrates significant efficacy with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. | |||
T61272 | EGFR/HER2-IN-7 | ||
EGFR/HER2-IN-7 is a highly selective and potent anticancer compound specifically designed to target MCF-7 breast cancer cells. It functions as a dual inhibitor, targeting both EGFR/HER2 kinases and DHFR (dihydrofolate reductase). Its inhibitory activities are measured with IC50 values of 0.18 μM for EGFR, 0.146 μM for HER2, and 0.907 μM for DHFR [1]. | |||
T36443 |
(R,R)-CXCR2-IN-2
(R,R)-CXCR2-IN-2 |
||
(R,R)-CXCR2-IN-2, diastereoisomer of CXCR2-IN-2 (compound 68), is a brain penetrant CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively[1]. [1]. Lu H, et al. Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists. J Med Chem. 2018;61(6):2518-2532. | |||
TP1683 |
[pSer2, pSer5, pSer7]-CTD
|
||
[pSer2, pSer5, pSer7]-CTD is a substrate for CDK7(cyclin-dependent protein kinase), a phosphorylated polypeptide at ser2, ser5, and ser7 of RNA polymerase II carboxyl terminus (CTD). | |||
T79009 |
VEGFR2-IN-3
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
VEGFR2-IN-3 (compound 385)为高效VEGFR2抑制剂。 | |||
T73504 |
MR2938
|
||
MR2938 是一种有效的AChE 抑制剂,IC50为 5.04 μM。 MR2938 也明显抑制 NO 的产生 (IC50= 3.29 μM)。 MR2938 通过阻断MAPK/JNK 和NF-κB 信号通路抑制神经炎症。 MR2938 可用于阿尔茨海默病 (AD) 研究。 | |||
T37506 |
MCTR2
MCTR2 |
||
Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase then to MCTR2 by γ-glutamyl transferase. MCTR2 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR2 prior to E. coli administration reduces neutrophil infiltration, shor... | |||
T62776 |
EGFR/HER2-IN-2
|
||
EGFR/HER2-IN-2 (Compound ZINC35560729) 是一种 EGFR 和 HER2 双重抑制剂,作用于 EGFR (IC50: 5.02 μM) 和 HER2 (IC50: 0.83 μM)。 | |||
T72854 |
EGFR/HER2-IN-9
|
||
EGFR/HER2-IN-9 是一种 EGFR 和 HER2抑制剂,对 EGFR、EGFR T790M 和 HER2 的 IC50分别为 3.2、8.3 和 14 nM。 | |||
T62777 |
EGFR/HER2-IN-3
|
||
EGFR/HER2-IN-3 (Compound ZINC21942954) 是一种双重的 EGFR 和 HER2 抑制剂。 | |||
T63401 |
EGFR/HER2/TS-IN-1
|
||
EGFR/HER2/TS-IN-1 是 EGFR、HER2和TS (Thymidylate synthase)抑制剂,他们的IC50值分别为 0.203、0.088 和 0.168 μM,具有诱导 MCF7 细胞凋亡(apoptosis)的作用。 | |||
T63161 |
EGFR/HER2/CDK9-IN-3
|
||
EGFR/HER2/CDK9-IN-3 (Compound 10) 是一种有效的 EGFR (IC50: 191.08 nM)、HER2 (IC50: 132.65 nM) 和 CDK9 (IC50: 113.98 nM) 抑制剂。EGFR/HER2/CDK9-IN-3 表现出明显的抗肿瘤作用。 | |||
T35924 |
Tat-NR2Baa
Tat-NR2Baa |
||
Tat-NR2BAA is an inactive control peptide of Tat-NR2B9c. It shares a similar sequence with Tat-NR2B9c, but possesses a double-point mutation in the COOH terminal tSXV motif. This mutation renders Tat-NR2BAA unable to bind PSD-95. Tat-NR2B9c, on the other hand, is a membrane-permeable peptide that interferes with PSD-95/NMDAR binding. This interference leads to the decoupling of NR2B- and/or NR2A-type NMDARs from PSD-95[1][2]. | |||
T82492 |
EGFR/HER2/DHFR-IN-3
|
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
EGFR/HER2/DHFR-IN-3(compound 4c)是一种针对EGFR和HER2的高效双重抑制剂,其IC50分别为0.138 μM和0.092 μM。该化合物同时对DHFR具有抑制作用,IC50为0.193 M。在生物活性方面,EGFR/HER2/DHFR-IN-3能够导致MCF7乳腺癌细胞周期在S期发生阻滞,并进而诱导细胞凋亡。 | |||
T82175 |
HR2-18
|
||
HR2-18为具有生物活性的肽类化合物,能够抑制SARS-CoV渗入细胞。 | |||
TP1583L |
HER2/neu (654-662) GP2 acetate
|
HER | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
HER2/neu (654-662) GP2 acetate 来源于人表皮生长因子受体 2 (HER2-Neu, 654-662)。 HER2/neu (654-662) GP2 acetate 诱导对各种上皮癌有反应的 HLA-A2 限制性细胞毒性 T 淋巴细胞。 | |||
T83485 |
[Thr28, Nle31]-Cholecystokinin (25-33), sulfated
|
||
[Thr28, Nle31]-Cholecystokinin (25-33) 是一种具备CCK8所有生物活性的胆囊收缩素 (CCK) 类似物,表现出食欲抑制功效。它在胃肠道系统和中枢神经系统中担任激素和神经递质角色。此肽通过 Thr28 和 Nle31 的特殊替代,展现出在酸性条件下的高稳定性,并能抵抗空气氧化(防止蛋氨酸受损)。其主要构象特征为以Thr4为核心的γ转角和Gly5分隔的C末端螺旋片段。 | |||
T62640 | FPR2 agonist 2 | ||
FPR2 agonist 2 是一种具有血脑屏障通透性的、有效的 FPR2 激动剂 (EC50: 0.13 nM)。FPR2 agonist 2 对促炎细胞因子的产生和 caspase-3 的活性具有抑制作用,抵消线粒体功能的变化。 | |||
T61235 | CXCR2 antagonist 5 | ||
CXCR2 antagonist 5 (compound 25) 是一种有效的CXCR2拮抗剂。 CXCR2 antagonist 5 显示出有效的CXCR2结合亲和力 (IC50=0.013 μM) 和钙动员 (IC50=0.1 μM)。 | |||
T60395 | Nrf2-ARE/hMAO-B/QR2 modulator 1 | ||
Nrf2-ARE/hMAO-B/QR2 modulator 1是一种新的基于白藜芦醇的多靶点定向配体(MTDL),显示出良好的平衡 MTDL 特征:细胞激活 Nrf2-ARE 通路(CD = 9.83 μM),选择性抑制 hMAO-B 和 QR2 (IC50s = 8.05和0.57 μM),并具有较佳的促进海马神经发生的能力。Nrf2-ARE/hMAO-B/QR2调节剂1在急性和慢性阿尔茨海默症模型中使用海马组织发挥神经保护和抗氧化作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S1587 |
Notoginsenoside R2
三七皂苷R2,20(S)-Notoginsenoside R2,Ginsenoside Ng-R2 |
Others; Nrf2 | Immunology/Inflammation; Others |
Notoginsenoside R2 (20(S)-Notoginsenoside R2) 是一种新分离三七皂苷,表现出对6-OHDA 诱导的氧化应激及细胞凋亡的保护作用。 | |||
TN2454 |
Stipuleanoside R2
屏边三七苷R2 |
Others | Others |
Stipuleanoside R2 is a triterpenoid saponin. It has a role as a metabolite. | |||
T33165 |
Majonoside R2
Majonoside R 2 |
||
Majonoside R2 is a major saponin constituent of Vietnamese ginseng. | |||
TN1101 |
20(R)-Notoginsenoside R2
R-三七皂苷R2,20(R)-三七皂苷R |
Others | Others |
20(R)-Notoginsenoside R2 is a natural product with Promote blood circulation and improve myocardial ischemia | |||
T17280 |
(Z)-Guggulsterone
|
Apoptosis; VEGFR; Akt | Angiogenesis; Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
(Z)-Guggulsterone 是印度阿育吠陀药用植物Commiphora mukul 的成分,可通过引起细胞凋亡来抑制人前列腺癌细胞的生长,还可通过抑制VEGF-VEGF-R2-Akt 信号传导轴来抑制血管生成。 | |||
T14055 |
5Z-7-Oxozeaenol
FR148083,L783279,LL-Z 1640-2 |
VEGFR; FLT; MEK; MAPK; PDGFR; Antibiotic; Src | Angiogenesis; MAPK; Microbiology/Virology; Tyrosine Kinase/Adaptors |
5Z-7-Oxozeaenol (FR148083) 是一种天然抗原生动物抑制剂,不可逆的选择性抑制 TAK1和 VEGF-R2,IC50值分别为 8 nM 和 52 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01185 |
DR5/TRAIL R2 Protein, Human, Recombinant (His)
KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1. | |||
TMPY-01697 |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)
Tnfr-1,TNFR80,TNF-R-II,TNF-αR2,tumor necrosis facto... |
Mouse | HEK293 Cells |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P25119. | |||
TMPY-02030 |
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T... |
Human | HEK293 Cells |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... | |||
TMPY-05388 |
DR5/TRAIL R2 Protein, Human, Recombinant (hFc)
tumor necrosis factor receptor superfamily, member 10b,TRAIL... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is AAB67103.1. | |||
TMPK-00277 |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
TRAIL R2,TNFRSF10B,TRICK2,KILLER,DR5,TRAIL receptor... |
Human | HEK293 Cells |
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. | |||
TMPY-05477 |
DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated
DR5,tumor necrosis factor receptor superfamily, member 10b,T... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is O14763-1. | |||
TMPY-06835 |
DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated
TRICK2A,DR5,tumor necrosis factor receptor superfamily, memb... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.54 kDa and the accession number is NP_003833.4. | |||
TMPK-00276 |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
ZTNFR9,DR5TRICK2B,DR5,TRAIL receptor 2,TRICKB,TNFRSF10B,TRIC... |
Human | HEK293 Cells |
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. | |||
TMPJ-00276 |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His)
DR5,TRAILR2,TRICK2,TNFRSF10B,KILLER,TNF-Related Apo... |
Human | HEK293 Cells |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 49 KDa and the accession number is O14763. | |||
TMPJ-00430 |
TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His)
Death Receptor 5,TRAILR2,CD262,DR5,TNFRSF10B,TRAIL-... |
Cynomolgus | HEK293 Cells |
TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 22-30 KDa and the accession number is A0A2K5TXK0. | |||
TMPJ-01198 |
UBE2R2 Protein, Human, Recombinant (His)
UBC3B,Ubiquitin-Conjugating Enzyme E2-CDC34B,CDC34B,Ubiquiti... |
Human | E. coli |
Ubiquitin-Conjugating Enzyme E2 R2 (UBE2R2) is a modification enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2R2 is involved in cell growth and transformation. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2R2 catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. It may be involved in degradation of katenin. | |||
TMPJ-00275 |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated
DR5,Tumor Necrosis Factor Receptor Superfamily Member 10B,TR... |
Human | HEK293 Cells |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 18-25 KDa and the accession number is O14763. | |||
TMPY-01696 |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc)
TNF-αR2,TNF-R-II,Tnfr2,TNFalpha-R2 |
Mouse | HEK293 Cells |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is P25119. | |||
TMPK-00637 |
IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)
β receptor10,IFNbR2,IFN α/β R2,IFN-R,IFNA<... |
Cynomolgus | HEK293 Cells |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-... | |||
TMPK-00889 |
IFNAR2 Protein, Human, Recombinant (aa 27-243, His)
IFN-alpha/beta R2,IFNAR2,IFNbR2,I... |
Human | HEK293 Cells |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His t... | |||
TMPY-02909 |
ASGR2 Protein, Human, Recombinant (His)
HBXBP,ASGPR2,HL-2,asialoglycoprotein receptor 2,ASG... |
Human | HEK293 Cells |
ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is ... | |||
TMPH-03153 |
Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His)
|
Porphyromonas gingivalis | E. coli |
Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms. Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with C-10xHis tag. The predicted molecular weight is 57.1 kDa and the accession number is P95493. | |||
TMPY-01437 |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His)
TRAILR2,MK,TRICKB,TRICK2B,TRICK2A,Ly98,DR5,KILLER,t... |
Mouse | HEK293 Cells |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is Q9QZM4. | |||
TMPK-01382 |
TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)
p75TNFR,p75TBPII,CD120b,TNF-R75,TNFR1B,TNFR2,TNF- |
Cynomolgus | HEK293 Cells |
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects o... | |||
TMPY-01452 |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)
TRICK2B,DR5,tumor necrosis factor receptor superfamily, memb... |
Mouse | HEK293 Cells |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q9QZM4. | |||
TMPJ-00246 |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)
MK,CD262,Tnfrsf10b,Dr5,Tumor necrosis factor receptor superf... |
Mouse | HEK293 Cells |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-75 KDa and the accession number is Q9QZM4. | |||
TMPJ-00245 |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated
Dr5,CD262,Death receptor 5,Tnfrsf10b,Killer,MK,Tumor necrosi... |
Mouse | HEK293 Cells |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 20-40 KDa and the accession number is Q9QZM4. | |||
TMPJ-00288 |
TNF RII Protein, Human, Recombinant (mFc)
Tumor necrosis factor receptor 2,TNFRSF1B,p75,TNF-RII,TNF- |
Human | HEK293 Cells |
TNF RII Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60 KDa and the accession number is P20333. | |||
TMPJ-00157 |
CD82 Protein, Human, Recombinant (hFc)
Tetraspanin-27,KAI1,ST6,TSPAN27,TSPAN274F9,CD82 molecule,Tsp... |
Human | HEK293 Cells |
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1... | |||
TMPJ-00287 |
TNF RII Protein, Human, Recombinant (hFc)
TNF-R2,Tumor necrosis factor receptor superfamily m... |
Human | HEK293 Cells |
TNF RII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is P20333. | |||
TMPY-01944 |
HER2/ERBB2 Protein, Rat, Recombinant (His)
EGFR2,erb-b2 receptor tyrosine kinase 2 |
Rat | HEK293 Cells |
HER2/ERBB2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.2 kDa and the accession number is AAH61863.1. | |||
TMPY-00972 |
FGFR2 Protein, Human, Recombinant (His & hFc)
K-SAM,TK14,BBDS,fibroblast growth factor receptor 2,BFR-1,CD... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1. | |||
TMPY-05442 |
KIR2DL3 Protein, Human, Recombinant (hFc)
KIR-K7b,CU464054.1,killer cell immunoglobulin like receptor,... |
Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q32WE4. | |||
TMPY-01985 |
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
FCGR2,FCGR21,CD32A,FCG2,CDw32,CD32B,FcGR,F... |
Human | HEK293 Cells |
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2. | |||
TMPY-00423 |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
BFR-1,KGFR,TK25,JWS,ECT1,K-SAM,FGFR2 α(IIIb),CD332,... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17. | |||
TMPY-04684 |
HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)
HERVWENV,MLN 19,HERV7Q,HERVW,CD340,NGL,erb-b2 receptor tyros... |
Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is P04626-1. | |||
TMPY-02361 |
VEGFR2/KDR Protein, Human, Recombinant (His)
VEGFR2,kinase insert domain receptor,VEGFR,FLK1,Flk... |
Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession number is P35968-1. | |||
TMPY-02469 |
HER2/ERBB2 Protein, Mouse, Recombinant (hFc)
EGFR2,c-erbB2,l11Jus8,Erbb-2,mKIAA3023,Neu,erb-b2 r... |
Mouse | HEK293 Cells |
HER2/ERBB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.7 kDa and the accession number is P70424. | |||
TMPY-02794 |
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TIL4,CD282,toll-like receptor 2 |
Human | Baculovirus Insect Cells |
TLR2 Protein, Human, Recombinant (aa 1-587, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 65.5 kDa and the accession number is O60603-1. | |||
TMPY-00654 |
ACVR2B Protein, Human, Recombinant (hFc)
activin A receptor, type IIB,HTX4,ActR-IIB,ACTRIIB,Activin R... |
Human | HEK293 Cells |
ACVR2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.0 kDa and the accession number is Q13705-1. | |||
TMPJ-00335 |
TGFBR2 Protein, Mouse, Recombinant (His)
TGFR-2,TGF-beta type II receptor,Transforming growth factor-... |
Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2. | |||
TMPY-04799 |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
IFN-R,interferon (α, β and Ω) receptor 2,IFNABR,interferon (... |
Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPY-05394 |
ROR2 Protein, Human, Recombinant (His)
BDB,BDB1,NTRKR2,receptor tyrosine kinase-like orpha... |
Human | HEK293 Cells |
ROR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.8 kDa and the accession number is Q01974. | |||
TMPY-02314 |
HER2/ERBB2 Protein, Mouse, Recombinant (His)
HER2,c-erbB2,erb-b2 receptor tyrosine kinase 2,Neu,... |
Mouse | HEK293 Cells |
HER2/ERBB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is P70424. | |||
TMPY-01366 |
IL-1R2 Protein, Human, Recombinant (His)
IL1R2c,interleukin 1 receptor, type II,IL-1RT2,CD12... |
Human | HEK293 Cells |
IL-1R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is P27930-1. | |||
TMPY-03101 |
TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His)
tumor necrosis factor receptor superfamily, member 1b |
Cynomolgus,Rhesus | HEK293 Cells |
TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is XP_005544817.1&NP_001253134.1. | |||
TMPY-01744 |
ACVR2A Protein, Human, Recombinant (His)
activin A receptor, type IIA,ACVR2,ACTRII |
Human | HEK293 Cells |
ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1. | |||
TMPY-01621 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
TIMD-3,hepatitis A virus cellular receptor 2,HAVcr-2,Tim-3,T... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPY-01281 |
ACVR2B Protein, Mouse, Recombinant (His)
ActRIIB,activin A receptor, type IIB,4930516B21Rik |
Mouse | HEK293 Cells |
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1. | |||
TMPY-01137 |
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE... |
Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1. | |||
TMPY-05227 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
TIMD3,hepatitis A virus cellular receptor 2,CD366,KIM-3,TIMD... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPY-01059 |
BMPR2 Protein, Human, Recombinant (His)
POVD1,PPH1,BMPR3,BRK-3,BMPR-II,bone morphogenetic protein re... |
Human | HEK293 Cells |
BMPR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is Q13873. | |||
TMPY-03079 |
IL-1R2 Protein, Mouse, Recombinant (His)
interleukin 1 receptor, type II,Il1r-2,CD121b |
Mouse | HEK293 Cells |
IL-1R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P27931. | |||
TMPY-02237 |
KIR2DL3 Protein, Human, Recombinant (His)
NKAT2,MGC129943,KIR-K7c,NKAT2B,CU464054.1,NKAT,KIR-023GB,p58... |
Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.9 kDa and the accession number is Q32WE4. | |||
TMPY-00636 |
HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)
erb-b2 receptor tyrosine kinase 2,EGFR2 |
Cynomolgus | HEK293 Cells |
HER2/ERBB2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is G7PUM4. | |||
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